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Conserved domains on  [gi|86171546|ref|XP_966233|]
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sphingomyelin synthase 1, putative [Plasmodium falciparum 3D7]

Protein Classification

sphingomyelin synthase family protein( domain architecture ID 10627211)

sphingomyelin synthase family protein belonging to the type 2 phosphatidic acid phosphatase (PAP2) superfamily, similar to phosphatidylinositol:ceramide inositolphosphotransferase that is capable of converting phosphatidylinositol (PI) and ceramide to inositol-phosphorylceramide (IPC) and diacylglycerol (DAG) and vice versa

CATH:  1.20.144.10
EC:  2.7.8.-
Gene Ontology:  GO:0016780|GO:0016310
PubMed:  9122162|14685263
SCOP:  3001110

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 266-336 2.04e-14

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


:

Pssm-ID: 464150  Cd Length: 74  Bit Score: 68.00  E-value: 2.04e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86171546   266 CTDLVISGHTAFTTLLTFFWFFYERNIY--VKTTIFLYSIYIYIIIIISRFHYTVDVLMGYVFGGSVFLFYHY 336
Cdd:pfam14360   2 CGDLIFSGHTVFTTLFVLFIWEYSPRRLwiLKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYHT 74
 
Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 266-336 2.04e-14

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


Pssm-ID: 464150  Cd Length: 74  Bit Score: 68.00  E-value: 2.04e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86171546   266 CTDLVISGHTAFTTLLTFFWFFYERNIY--VKTTIFLYSIYIYIIIIISRFHYTVDVLMGYVFGGSVFLFYHY 336
Cdd:pfam14360   2 CGDLIFSGHTVFTTLFVLFIWEYSPRRLwiLKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYHT 74
 
Name Accession Description Interval E-value
PAP2_C pfam14360
PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.
 266-336 2.04e-14

PAP2 superfamily C-terminal; This family is closely related to the C-terminal a region of PAP2.


Pssm-ID: 464150  Cd Length: 74  Bit Score: 68.00  E-value: 2.04e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 86171546   266 CTDLVISGHTAFTTLLTFFWFFYERNIY--VKTTIFLYSIYIYIIIIISRFHYTVDVLMGYVFGGSVFLFYHY 336
Cdd:pfam14360   2 CGDLIFSGHTVFTTLFVLFIWEYSPRRLwiLKVILWLLAAIGYFLIIASRKHYTVDVLLGYYITTLVFLLYHT 74
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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