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Conserved domains on  [gi|850990953|ref|WP_048061088|]
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MULTISPECIES: nitrogenase iron protein [Methanothermobacter]

Protein Classification

nitrogenase iron protein( domain architecture ID 10793759)

nitrogenase iron protein NifH is the component II of nitogenase, which is responsible for the biological nitrogen fixation (reduction of molecular nitrogen to ammonia) in an ATP-dependent process

Gene Ontology:  GO:0016163|GO:0009399
PubMed:  8990309|10903367|12823187|8226614|8286368

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
nifH PRK13233
nitrogenase iron protein;
1-275 0e+00

nitrogenase iron protein;


:

Pssm-ID: 183905  Cd Length: 275  Bit Score: 569.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYFHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVACTPDKVIETGF 80
Cdd:PRK13233   1 MTRKIAIYGKGGIGKSTTTQNTAAAMAYFHDKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGEEKVTPDKVIKTGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:PRK13233  81 KDIRCVESGGPEPGVGCAGRGVITAIDLMEENGAYTDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:PRK13233 161 ANNICKGLVKYAEQSGVRLGGIICNSRNVDGELELLEEFTDAIGTQMIHFVPRDNIVQKAEFNKKTVVEFDPDCNQAKEY 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:PRK13233 241 KELARKIIENKDFVIPKPLTMDELEEMVVKYGLMD 275
 
Name Accession Description Interval E-value
nifH PRK13233
nitrogenase iron protein;
1-275 0e+00

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 569.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYFHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVACTPDKVIETGF 80
Cdd:PRK13233   1 MTRKIAIYGKGGIGKSTTTQNTAAAMAYFHDKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGEEKVTPDKVIKTGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:PRK13233  81 KDIRCVESGGPEPGVGCAGRGVITAIDLMEENGAYTDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:PRK13233 161 ANNICKGLVKYAEQSGVRLGGIICNSRNVDGELELLEEFTDAIGTQMIHFVPRDNIVQKAEFNKKTVVEFDPDCNQAKEY 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:PRK13233 241 KELARKIIENKDFVIPKPLTMDELEEMVVKYGLMD 275
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-275 0e+00

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 539.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEvACTPDKVIETGF 80
Cdd:COG1348    1 MMRQIAIYGKGGIGKSTTSSNLSAALAE-MGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKGE-DVELEDIVFEGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:COG1348   79 GGVKCVEAGGPEPGVGCAGRGIITAIELLEELGAYEEDLDVVIYDVLGDVVCGGFAMPIREGYADEIYIVTSGEFMALYA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:COG1348  159 ANNICKGIKKYANRGGVRLGGIICNSRNVDGERELVEEFAERLGTQIIAFVPRSNIVQRAELNGKTVIEYAPDSEQADEY 238

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:COG1348  239 RELAKKILENKKLVIPKPLSDEELEELLLEYGILE 273
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 3-275 0e+00

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 498.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953    3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVACTPDKVIETGFGG 82
Cdd:TIGR01287   1 RQIAIYGKGGIGKSTTTQNIAAALAEM-GKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGAEDLELEDVIKEGFGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:TIGR01287  80 IRCVESGGPEPGVGCAGRGVITAINLLEELGAYEDDLDFVFYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMALYAAN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  163 NICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:TIGR01287 160 NICKGILKYAKSGGVRLGGLICNSRNVDDEKELIDEFAKKLGTQLIHFVPRSNIVQKAEIRKMTVIEYDPESEQANEYRE 239

                         250       260       270
                  ....*....|....*....|....*....|...
gi 850990953  243 LARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:TIGR01287 240 LAKKIYENTEFVIPTPLTMDELEEILMKFGIML 272
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 3-267 1.37e-175

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 484.32  E-value: 1.37e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVAcTPDKVIETGFGG 82
Cdd:cd02040    1 RQIAIYGKGGIGKSTTASNLSAALAEM-GKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKGEVE-ELEDVIKEGFNG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:cd02040   79 IKCVESGGPEPGVGCAGRGIITAINLLEELGAYEEDLDVVFYDVLGDVVCGGFAMPIREGYADEVYIVTSGEMMALYAAN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 163 NICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:cd02040  159 NIAKGIVKYAERGGVRLGGLICNSRNVDREEELVEEFAERLGTQIIHFVPRSNEVQEAELRGKTVIEYDPDSEQADEYRE 238

                        250       260
                 ....*....|....*....|....*
gi 850990953 243 LARKIIENKDFVIPEPMTMDEMEEL 267
Cdd:cd02040  239 LAKKILENKKLVIPKPLTMEELEEL 263
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 3-267 7.05e-148

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 414.27  E-value: 7.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVacTPDKVIETGFGG 82
Cdd:NF033200   1 KQIAIYGKGGIGKSTTVSNLAAALSE-EGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENKNI--KEEDVVFEGYGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:NF033200  78 VRCVESGGPEPGVGCAGRGIIVAMQLLEKLGAFMEDLDVIIYDVLGDVVCGGFAVPLREGYADEVYIVTSGEYMSLYAAN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 163 NICKGMVKYARqsgvRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:NF033200 158 NICKGIKKLKG----RLGGIICNSRNIENEEEIVEEFAERIGSRLIGFIPRSELVQKSELEAKTVIEKAPDSEQAAVYRK 233

                        250       260
                 ....*....|....*....|....*
gi 850990953 243 LARKIIENKDFVIPEPMTMDEMEEL 267
Cdd:NF033200 234 LAKKIMENTDFVIPEPLEDEELEEL 258
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
3-274 4.07e-141

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 397.58  E-value: 4.07e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953    3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVA-CTPDKVIETGFG 81
Cdd:pfam00142   1 RQIAIYGKGGIGKSTTSQNLSAALAEM-GKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEdVEVEDVVYKGYG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   82 GIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEkDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAA 161
Cdd:pfam00142  80 GVKCVESGGPEPGVGCAGRGVITAINLLEELGAYD-DLDFVLYDVLGDVVCGGFAMPIREGKAQEIYIVTSNEMMALYAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  162 NNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYR 241
Cdd:pfam00142 159 NNIAKGIQKYAKSGGVRLGGIICNSRKVDDERELIDAFAEELGTQVLHFVPRDNIVRKAELRKQTVIEYAPDSEQAQEYR 238

                         250       260       270
                  ....*....|....*....|....*....|...
gi 850990953  242 ELARKIIENKDFVIPEPMTMDEMEELVVKYGVM 274
Cdd:pfam00142 239 ELARKILENPKGTIPTPLSMDELEALLEDFGLM 271
 
Name Accession Description Interval E-value
nifH PRK13233
nitrogenase iron protein;
1-275 0e+00

nitrogenase iron protein;


Pssm-ID: 183905  Cd Length: 275  Bit Score: 569.84  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYFHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVACTPDKVIETGF 80
Cdd:PRK13233   1 MTRKIAIYGKGGIGKSTTTQNTAAAMAYFHDKKVFIHGCDPKADSTRLILGGKPQTTMMDTLRELGEEKVTPDKVIKTGF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:PRK13233  81 KDIRCVESGGPEPGVGCAGRGVITAIDLMEENGAYTDDLDFVFFDVLGDVVCGGFAMPIRDGKAQEVYIVASGEMMAIYA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:PRK13233 161 ANNICKGLVKYAEQSGVRLGGIICNSRNVDGELELLEEFTDAIGTQMIHFVPRDNIVQKAEFNKKTVVEFDPDCNQAKEY 240

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:PRK13233 241 KELARKIIENKDFVIPKPLTMDELEEMVVKYGLMD 275
NifH/CfbC COG1348
Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport ...
 1-275 0e+00

Nitrogenase ATPase subunit NifH/coenzyme F430 biosynthesis subunit CfbC [Coenzyme transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440959  Cd Length: 276  Bit Score: 539.37  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEvACTPDKVIETGF 80
Cdd:COG1348    1 MMRQIAIYGKGGIGKSTTSSNLSAALAE-MGKKVMQIGCDPKADSTRLLLGGKRIPTVLDTLREKGE-DVELEDIVFEGF 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:COG1348   79 GGVKCVEAGGPEPGVGCAGRGIITAIELLEELGAYEEDLDVVIYDVLGDVVCGGFAMPIREGYADEIYIVTSGEFMALYA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:COG1348  159 ANNICKGIKKYANRGGVRLGGIICNSRNVDGERELVEEFAERLGTQIIAFVPRSNIVQRAELNGKTVIEYAPDSEQADEY 238

                        250       260       270
                 ....*....|....*....|....*....|....*
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:COG1348  239 RELAKKILENKKLVIPKPLSDEELEELLLEYGILE 273
nifH TIGR01287
nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also ...
 3-275 0e+00

nitrogenase iron protein; This model describes nitrogenase (EC 1.18.6.1) iron protein, also called nitrogenase reductase or nitrogenase component II. This model includes molybdenum-iron nitrogenase reductase (nifH), vanadium-iron nitrogenase reductase (vnfH), and iron-iron nitrogenase reductase (anfH). The model excludes the homologous protein from the light-independent protochlorophyllide reductase. [Central intermediary metabolism, Nitrogen fixation]


Pssm-ID: 273538  Cd Length: 275  Bit Score: 498.84  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953    3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVACTPDKVIETGFGG 82
Cdd:TIGR01287   1 RQIAIYGKGGIGKSTTTQNIAAALAEM-GKKVMIVGCDPKADSTRLLLGGKAQPTVLDVLREKGAEDLELEDVIKEGFGG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:TIGR01287  80 IRCVESGGPEPGVGCAGRGVITAINLLEELGAYEDDLDFVFYDVLGDVVCGGFAMPIREGKAQEIYIVTSGEMMALYAAN 159

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  163 NICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:TIGR01287 160 NICKGILKYAKSGGVRLGGLICNSRNVDDEKELIDEFAKKLGTQLIHFVPRSNIVQKAEIRKMTVIEYDPESEQANEYRE 239

                         250       260       270
                  ....*....|....*....|....*....|...
gi 850990953  243 LARKIIENKDFVIPEPMTMDEMEELVVKYGVMD 275
Cdd:TIGR01287 240 LAKKIYENTEFVIPTPLTMDELEEILMKFGIML 272
NifH cd02040
nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. ...
 3-267 1.37e-175

nitrogenase component II NifH; NifH gene encodes component II (iron protein) of nitrogenase. Nitrogenase is responsible for the biological nitrogen fixation, i.e. reduction of molecular nitrogen to ammonia. NifH consists of two oxygen-sensitive metallosulfur proteins: the mollybdenum-iron (alternatively, vanadium-iron or iron-iron) protein (commonly referred to as component 1), and the iron protein (commonly referred to as component 2). The iron protein is a homodimer, with an Fe4S4 cluster bound between the subunits and two ATP-binding domains. It supplies energy by ATP hydrolysis, and transfers electrons from reduced ferredoxin or flavodoxin to component 1 for the reduction of molecular nitrogen to ammonia.


Pssm-ID: 349759  Cd Length: 265  Bit Score: 484.32  E-value: 1.37e-175
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVAcTPDKVIETGFGG 82
Cdd:cd02040    1 RQIAIYGKGGIGKSTTASNLSAALAEM-GKKVLHVGCDPKADSTRLLLGGKAIPTVLDTLREKGEVE-ELEDVIKEGFNG 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:cd02040   79 IKCVESGGPEPGVGCAGRGIITAINLLEELGAYEEDLDVVFYDVLGDVVCGGFAMPIREGYADEVYIVTSGEMMALYAAN 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 163 NICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:cd02040  159 NIAKGIVKYAERGGVRLGGLICNSRNVDREEELVEEFAERLGTQIIHFVPRSNEVQEAELRGKTVIEYDPDSEQADEYRE 238

                        250       260
                 ....*....|....*....|....*
gi 850990953 243 LARKIIENKDFVIPEPMTMDEMEEL 267
Cdd:cd02040  239 LAKKILENKKLVIPKPLTMEELEEL 263
F430_CfbC NF033200
Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, ...
 3-267 7.05e-148

Ni-sirohydrochlorin a,c-diamide reductive cyclase ATP-dependent reductase subunit; This family, very closely related to the nitrogenase iron protein, was identified as a subunit involved in biosynthesis of coenzyme F430 in archaeal methanogens and archaeal anaerobic methanotrophs.


Pssm-ID: 380202  Cd Length: 260  Bit Score: 414.27  E-value: 7.05e-148
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVacTPDKVIETGFGG 82
Cdd:NF033200   1 KQIAIYGKGGIGKSTTVSNLAAALSE-EGKKVMVIGCDPKADSTRTLMGGRRIPTILDLLRENKNI--KEEDVVFEGYGG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  83 IKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAAN 162
Cdd:NF033200  78 VRCVESGGPEPGVGCAGRGIIVAMQLLEKLGAFMEDLDVIIYDVLGDVVCGGFAVPLREGYADEVYIVTSGEYMSLYAAN 157

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 163 NICKGMVKYARqsgvRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRE 242
Cdd:NF033200 158 NICKGIKKLKG----RLGGIICNSRNIENEEEIVEEFAERIGSRLIGFIPRSELVQKSELEAKTVIEKAPDSEQAAVYRK 233

                        250       260
                 ....*....|....*....|....*
gi 850990953 243 LARKIIENKDFVIPEPMTMDEMEEL 267
Cdd:NF033200 234 LAKKIMENTDFVIPEPLEDEELEEL 258
Fer4_NifH pfam00142
4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;
3-274 4.07e-141

4Fe-4S iron sulfur cluster binding proteins, NifH/frxC family;


Pssm-ID: 395090  Cd Length: 271  Bit Score: 397.58  E-value: 4.07e-141
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953    3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEVA-CTPDKVIETGFG 81
Cdd:pfam00142   1 RQIAIYGKGGIGKSTTSQNLSAALAEM-GKKVLVVGCDPKADSTRLLLGGKLQPTVLDTAREKGYVEdVEVEDVVYKGYG 79

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   82 GIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEkDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAA 161
Cdd:pfam00142  80 GVKCVESGGPEPGVGCAGRGVITAINLLEELGAYD-DLDFVLYDVLGDVVCGGFAMPIREGKAQEIYIVTSNEMMALYAA 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  162 NNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYR 241
Cdd:pfam00142 159 NNIAKGIQKYAKSGGVRLGGIICNSRKVDDERELIDAFAEELGTQVLHFVPRDNIVRKAELRKQTVIEYAPDSEQAQEYR 238

                         250       260       270
                  ....*....|....*....|....*....|...
gi 850990953  242 ELARKIIENKDFVIPEPMTMDEMEELVVKYGVM 274
Cdd:pfam00142 239 ELARKILENPKGTIPTPLSMDELEALLEDFGLM 271
NifH-like cd02117
NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) ...
 3-267 2.59e-113

NifH family; This family contains the NifH (iron protein) of nitrogenase, L subunit (BchL/ChlL) of the protochlorophyllide reductase, and the BchX subunit of the Chlorophyllide reductase. Members of this family use energy from ATP hydrolysis and transfer electrons through a Fe4-S4 cluster to other subunit for substrate reduction


Pssm-ID: 349761  Cd Length: 266  Bit Score: 327.01  E-value: 2.59e-113
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRELGEV-ACTPDKVIETGFG 81
Cdd:cd02117    1 ESIVVYGKGGIGKSTTASNLSAALAEG-GKKVLHVGCDPKHDSTLLLTGGKVPPTIDEMLTEDGTAeELRREDLLFSGFN 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  82 GIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAA 161
Cdd:cd02117   80 GVDCVEAGGPEPGVGCGGRGIGTMLELLEEHGLLDDDYDVVIFDVLGDVVCGGFAAPLRRGFAQKVVIVVSEELMSLYAA 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 162 NNICKGMVKYARQsGVRLGGIICNSRNvDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYR 241
Cdd:cd02117  160 NNIVKAVENYSKN-GVRLAGLVANLRD-PAGTEEIQAFAAAVGTKILAVIPRDPAVRRAELARVTVFEHDPVSPAASEFA 237

                        250       260
                 ....*....|....*....|....*..
gi 850990953 242 ELARKIIENKDFVI-PEPMTMDEMEEL 267
Cdd:cd02117  238 RLAAKIADAVPPVPgPRPLSDRELFAL 264
PRK13230 PRK13230
nitrogenase reductase-like protein; Reviewed
 2-267 4.24e-107

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183903  Cd Length: 279  Bit Score: 311.71  E-value: 4.24e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   2 VRKIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMqTTMMDTLRELGEVACTPDKVIETGFG 81
Cdd:PRK13230   1 MRKFCFYGKGGIGKSTTVCNIAAALAE-SGKKVLVVGCDPKADCTRNLVGEKI-PTVLDVLREKGIDNLGLEDIIYEGFN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  82 GIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEK-DLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:PRK13230  79 GIYCVESGGPEPGYGCAGRGVITAIDLLKKLGVFEElGPDVVIYDILGDVVCGGFAMPLQKGLADDVYIVTTCDPMAIYA 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARQSGVRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:PRK13230 159 ANNICKGIKRFAKRGKSALGGIIYNGRSVIDAPDIVEEFAKKIGTNVIGKIPMSNIITEAEIYGKTVIEYAPDSEISNIF 238

                        250       260
                 ....*....|....*....|....*..
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEEL 267
Cdd:PRK13230 239 RELAEAIYENNTGTIPNPLEEEEIDQI 265
PRK13231 PRK13231
nitrogenase reductase-like protein; Reviewed
 1-271 5.65e-105

nitrogenase reductase-like protein; Reviewed


Pssm-ID: 183904  Cd Length: 264  Bit Score: 305.57  E-value: 5.65e-105
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYFHgkNVMIHGCDPKADSTRlILGGKMQTTMMDTLRELGEVACtpDKVIETGF 80
Cdd:PRK13231   1 VMKKIAIYGKGGIGKSTTVSNMAAAYSNDH--RVLVIGCDPKADTTR-TLCGKRIPTVLDTLKDNRKPEL--EDIIHEGF 75

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYA 160
Cdd:PRK13231  76 NGILCVESGGPEPGVGCAGRGVIVAMNLLENLGVFDEDIDVVIYDVLGDVVCGGFSVPLREDYADEVYIVTSGEYMSLYA 155

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 161 ANNICKGMVKYARqsgvRLGGIICNSRNVDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEY 240
Cdd:PRK13231 156 ANNIARGIKKLKG----KLGGIICNCRGIDNEVEIVSEFASRIGSRIIGVIPRSNLVQESELDAKTVVETFPESEQASVY 231

                        250       260       270
                 ....*....|....*....|....*....|.
gi 850990953 241 RELARKIIENKDFVIPEPMTMDEMEELVVKY 271
Cdd:PRK13231 232 RKLANNIMNNTEFSTPEPMDDEEFEEFFKSF 262
chlL PRK13185
protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional
 1-268 2.91e-73

protochlorophyllide reductase iron-sulfur ATP-binding protein; Provisional


Pssm-ID: 237293  Cd Length: 270  Bit Score: 225.23  E-value: 2.91e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   1 MVRKIAIYGKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTrLILGGKMQTTMMDTLRELG----EVacTPDKVI 76
Cdd:PRK13185   1 MALVLAVYGKGGIGKSTTSSNLSAAFAKL-GKKVLQIGCDPKHDST-FTLTGKLVPTVIDILEEVDfhseEL--RPEDFV 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  77 ETGFGGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEkDLDFVFFDVLGDVVCGGFAMPVRdgKAEEIYIVASGEMM 156
Cdd:PRK13185  77 YEGYNGVDCVEAGGPPAGTGCGGYVVGETVKLLKEHHLLD-DYDVILFDVLGDVVCGGFAAPLQ--YADYALIVTANDFD 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 157 ALYAANNICKGMVKYARQSGVRLGGIICNSrnvDGEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQ 236
Cdd:PRK13185 154 SIFAANRIAAAIQAKAKNYKVRLAGVIANR---SAGTDLIDKFNEAVGLKVLAHVPDLDAIRRSRLKGKTLFEMEETDPG 230

                        250       260       270
                 ....*....|....*....|....*....|....*.
gi 850990953 237 ----SQEYRELARKIIENKDFVIPEPMTMDEMEELV 268
Cdd:PRK13185 231 leevQNEYLRLAEQLLAGPEPLVPKPLKDREIFELL 266
Bchl-like cd02032
L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. ...
 4-268 2.41e-71

L-subunit of protochlorophyllide reductase; This family of proteins contains BchL and ChlL. Protochlorophyllide reductase catalyzes the reductive formation of chlorophyllide from protochlorophyllide during biosynthesis of chlorophylls and bacteriochlorophylls. Three genes, bchL, bchN and bchB, are involved in light-independent protochlorophyllide reduction in bacteriochlorophyll biosynthesis. In cyanobacteria, algae, and gymnosperms, three similar genes, chlL, chlN and chlB are involved in protochlorophyllide reduction during chlorophylls biosynthesis. BchL/chlL, bchN/chlN and bchB/chlB exhibit significant sequence similarity to the nifH, nifD and nifK subunits of nitrogenase, respectively. Nitrogenase catalyzes the reductive formation of ammonia from dinitrogen.


Pssm-ID: 349752  Cd Length: 267  Bit Score: 220.25  E-value: 2.41e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   4 KIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTrLILGGKMQTTMMDTLRELG----EVacTPDKVIETG 79
Cdd:cd02032    2 VIAVYGKGGIGKSTTSSNLSAAFAK-RGKKVLQIGCDPKHDST-FTLTGFLIPTVIDVLQSVDfhyeEV--WPEDVIFTG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  80 FGGIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEkDLDFVFFDVLGDVVCGGFAMPVRdgKAEEIYIVASGEMMALY 159
Cdd:cd02032   78 YGGVDCVEAGGPPAGTGCGGYVVGETVKLLKELNAFD-EYDVILFDVLGDVVCGGFAAPLN--YADYCLIVTANDFDSLF 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 160 AANNICKGMVKYARQSGVRLGGIICN-SRNVDgekeLLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEFD---PECN 235
Cdd:cd02032  155 AANRIAAAVREKAKTYPVRLAGIIGNrTDKTD----LIDKFVEAVPMPVLEVLPLIEDIRRSRVKGKTLFEMEesePELN 230

                        250       260       270
                 ....*....|....*....|....*....|....
gi 850990953 236 Q-SQEYRELARKIIENKDFVIPEPMTMDEMEELV 268
Cdd:cd02032  231 YvCDEYLNIADQLLSDPEGVVPKPLPDREIFDLL 264
BchX cd02033
X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls ...
 5-264 9.00e-47

X-subunit of protochlorophyllide reductase; Chlorophyllide reductase converts chlorophylls into bacteriochlorophylls by reducing the chlorin B-ring. This family contains the X subunit of this three-subunit enzyme. Sequence and structure similarity between bchX, protochlorophyllide reductase L subunit (bchL and chlL) and nitrogenase Fe protein (nifH gene) suggest their functional similarity. Members of the BchX family serve as the unique electron donors to their respective catalytic subunits (bchN-bchB, bchY-bchZ and nitrogenase component 1). Mechanistically, they hydrolyze ATP and transfer electrons through a Fe4-S4 cluster.


Pssm-ID: 349753  Cd Length: 329  Bit Score: 159.23  E-value: 9.00e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   5 IAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTL---RELGEVACTPDKVIETGfg 81
Cdd:cd02033   34 IAIYGKGGIGKSFTLANLSYMMAQ-QGKRVLLIGCDPKSDTTSLLFGGKACPTIIETStrkKLAGEEVKIGDVCFKRG-- 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  82 GIKCVESGGPEPGVGCAGRGVITAITLMERHGVYEKDLDFVFFDVLGDVVCGGFAMPVRDGKAEEIYIVASGEMMALYAA 161
Cdd:cd02033  111 GVFAMELGGPEVGRGCGGRGIIHGFELLEKLGFHDWGFDYVLLDFLGDVVCGGFGLPIARDMCQKVIVVGSNDLQSLYVA 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 162 NNICKGmVKYARQSG--VRLGGIICNSRNVDGEKellEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIEfdPECNQSQE 239
Cdd:cd02033  191 NNVCSA-VEYFRKLGgnVGVAGIVINKDDGTGEA---QAFAKAAGIPVLAAIPADEDIRRKSANYQIVGR--PETQWGPL 264

                        250       260
                 ....*....|....*....|....*
gi 850990953 240 YRELARKIIENKDfVIPEPMTMDEM 264
Cdd:cd02033  265 FAELATNVAEAPP-MRPTPLSQDEL 288
chlL CHL00072
photochlorophyllide reductase subunit L
 4-256 2.12e-42

photochlorophyllide reductase subunit L


Pssm-ID: 177011  Cd Length: 290  Bit Score: 146.81  E-value: 2.12e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   4 KIAIYGKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTrLILGGKMQTTMMDTLRE----LGEVacTPDKVIETG 79
Cdd:CHL00072   2 KLAVYGKGGIGKSTTSCNISIALAR-RGKKVLQIGCDPKHDST-FTLTGFLIPTIIDTLQSkdyhYEDV--WPEDVIYKG 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  80 FGGIKCVESGGPEPGVGCAGRGV-ITAITLMERHGVYEKDLdfVFFDVLGDVVCGGFAMPVrdGKAEEIYIVASGEMMAL 158
Cdd:CHL00072  78 YGGVDCVEAGGPPAGAGCGGYVVgETVKLLKELNAFYEYDI--ILFDVLGDVVCGGFAAPL--NYADYCIIITDNGFDAL 153

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 159 YAANNICKGMVKYARQSGVRLGGIICNSRNvdgEKELLEEFCERIGTQMIHFVPRDNIVQKAEFNKKSVIE---FDPECN 235
Cdd:CHL00072 154 FAANRIAASVREKARTHPLRLAGLVGNRTS---KRDLIDKYVEACPMPVLEVLPLIEDIRVSRVKGKTLFEmveSEPSLN 230

                        250       260
                 ....*....|....*....|..
gi 850990953 236 QSQE-YRELARKIIENKDFVIP 256
Cdd:CHL00072 231 YVCDyYLNIADQLLSQPEGVVP 252
ParA COG1192
ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein ...
 3-249 1.85e-15

ParA-like ATPase involved in chromosome/plasmid partitioning or cellulose biosynthesis protein BcsQ [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440805 [Multi-domain]  Cd Length: 253  Bit Score: 73.74  E-value: 1.85e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIY-GKGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLiLGGKMQT---TMMDTLRELGEVActpDKVIET 78
Cdd:COG1192    2 KVIAVAnQKGGVGKTTTAVNLAAALAR-RGKRVLLIDLDPQGNLTSG-LGLDPDDldpTLYDLLLDDAPLE---DAIVPT 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  79 GFGGIKCVESGGPEPGVgcagrgvitAITLMERHGV----------YEKDLDFVFFDvlgdvvCGGF-------AMPVrd 141
Cdd:COG1192   77 EIPGLDLIPANIDLAGA---------EIELVSRPGRelrlkralapLADDYDYILID------CPPSlglltlnALAA-- 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 142 gkAEEIYIVASGEMMALYAANNICK--GMVKYARQSGVRLGGIICN---SRNVDgEKELLEEFCERIGTQMI-HFVPRDN 215
Cdd:COG1192  140 --ADSVLIPVQPEYLSLEGLAQLLEtiEEVREDLNPKLEILGILLTmvdPRTRL-SREVLEELREEFGDKVLdTVIPRSV 216

                        250       260       270
                 ....*....|....*....|....*....|....
gi 850990953 216 IVQKAEFNKKSVIEFDPECNQSQEYRELARKIIE 249
Cdd:COG1192  217 ALAEAPSAGKPVFEYDPKSKGAKAYRALAEELLE 250
FlhG COG0455
MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell ...
 21-249 3.19e-09

MinD-like ATPase FlhG/YlxH, activator of the FlhF-type GTPase [Cell cycle control, cell division, chromosome partitioning, Cell motility];


Pssm-ID: 440223 [Multi-domain]  Cd Length: 230  Bit Score: 55.67  E-value: 3.19e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  21 NTAAAMSYfHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRElgevACTPDKVIETGFGGIKCVeSGGPEPGVgcagr 100
Cdd:COG0455    5 NLAAALAR-LGKRVLLVDADLGLANLDVLLGLEPKATLADVLAG----EADLEDAIVQGPGGLDVL-PGGSGPAE----- 73

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 101 gvITAITLMER----HGVYEKDLDFVFFDV---LGDVVCGGFAMpvrdgkAEEIYIVASGEMMALYAAnnicKGMVKYAR 173
Cdd:COG0455   74 --LAELDPEERlirvLEELERFYDVVLVDTgagISDSVLLFLAA------ADEVVVVTTPEPTSITDA----YALLKLLR 141

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 174 QS-GVRLGGIICN-SRNVDGEKEL---LEEFCER---IGTQMIHFVPRDNIVQKAEFNKKSVIEFDPECNQSQEYRELAR 245
Cdd:COG0455  142 RRlGVRRAGVVVNrVRSEAEARDVferLEQVAERflgVRLRVLGVIPEDPAVREAVRRGRPLVLAAPDSPAARAIRELAA 221


                 ....
gi 850990953 246 KIIE 249
Cdd:COG0455  222 RLAG 225
FlhG-like cd02038
MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) ...
 3-233 1.58e-05

MinD-like ATPase FlhG; FlhG is a member of the SIMIBI superfamily. FlhG (also known as YlxH) is a major determinant for a variety of flagellation patterns. It effects location and number of bacterial flagella during C-ring assembly.


Pssm-ID: 349758 [Multi-domain]  Cd Length: 230  Bit Score: 44.87  E-value: 1.58e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   3 RKIAIY-GKGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADSTRLILGGKMQTTMMDTL---RELGEVAC-TPDKVie 77
Cdd:cd02038    1 RIIAVTsGKGGVGKTNVSANLALALSKL-GKRVLLLDADLGLANLDILLGLAPKKTLGDVLkgrVSLEDIIVeGPEGL-- 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  78 tgfggikCVESGGpepgvgcAGRGVITAIT------LMERHGVYEKDLDFVFFDvLGdvvcGGFAMPVRD--GKAEEIYI 149
Cdd:cd02038   78 -------DIIPGG-------SGMEELANLDpeqkakLIEELSSLESNYDYLLID-TG----AGISRNVLDflLAADEVIV 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953 150 VASGE---MMALYAannickgMVK--YARQSGVRLGGIICNSRNVDGEKELLEEF---CER---IGTQMIHFVPRDNIVQ 218
Cdd:cd02038  139 VTTPEptsITDAYA-------LIKvlSRRGGKKNFRLIVNMARSPKEGRATFERLkkvAKRfldINLDFVGFIPYDQSVR 211

                        250
                 ....*....|....*
gi 850990953 219 KAEFNKKSVIEFDPE 233
Cdd:cd02038  212 RAVRSQKPFVLLFPN 226
ParAB_family cd02042
partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved ...
 3-49 3.58e-05

partition proteins ParAB family; ParA and ParB of Caulobacter crescentus belong to a conserved family of bacterial proteins implicated in chromosome segregation. ParB binds to DNA sequences adjacent to the origin of replication and localizes to opposite cell poles shortly following the initiation of DNA replication. ParB regulates the ParA ATPase activity by promoting nucleotide exchange in a fashion reminiscent of the exchange factors of eukaryotic G proteins. ADP-bound ParA binds single-stranded DNA, whereas the ATP-bound form dissociates ParB from its DNA binding sites. Increasing the fraction of ParA-ADP in the cell inhibits cell division, suggesting that this simple nucleotide switch may regulate cytokinesis. ParA shares sequence similarity to a conserved and widespread family of ATPases which includes the repA protein of the repABC operon in Rhizobium etli symbiotic plasmid. This operon is involved in the plasmid replication and partition.


Pssm-ID: 349760 [Multi-domain]  Cd Length: 130  Bit Score: 42.53  E-value: 3.58e-05
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*...
gi 850990953   3 RKIAIYG-KGGIGKSTTQQNTAAAMSYfHGKNVMIHGCDPKADSTRLI 49
Cdd:cd02042    1 KVIAVANqKGGVGKTTLAVNLAAALAL-RGKRVLLIDLDPQGSLTSWL 47
Mrp COG0489
Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, ...
 2-194 3.82e-04

Fe-S cluster carrier ATPase, Mrp/ApbC/NBP35 family [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440255 [Multi-domain]  Cd Length: 289  Bit Score: 41.33  E-value: 3.82e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   2 VRKIAIY-GKGGIGKSTTQQNTAAAMSyFHGKNVMIHGCDPKADSTRLILGGKMQTTMMDTLRelGEVAcTPDKVIETGF 80
Cdd:COG0489   92 LEVIAVTsGKGGEGKSTVAANLALALA-QSGKRVLLIDADLRGPSLHRMLGLENRPGLSDVLA--GEAS-LEDVIQPTEV 167

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  81 GGIKCVESGG-PEPGVGCAGRGVITAitLMERhgvYEKDLDFVFFD---VLGDV-------VCGGFAMPVRDGKAEEIYI 149
Cdd:COG0489  168 EGLDVLPAGPlPPNPSELLASKRLKQ--LLEE---LRGRYDYVIIDtppGLGVAdatllasLVDGVLLVVRPGKTALDDV 242

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 850990953 150 VASGEMmalyaannickgmvkyARQSGVRLGGIICNSRNVDGEKE 194
Cdd:COG0489  243 RKALEM----------------LEKAGVPVLGVVLNMVCPKGERY 271
AAA_31 pfam13614
AAA domain; This family includes a wide variety of AAA domains including some that have lost ...
 3-46 3.89e-04

AAA domain; This family includes a wide variety of AAA domains including some that have lost essential nucleotide binding residues in the P-loop.


Pssm-ID: 433350 [Multi-domain]  Cd Length: 177  Bit Score: 40.26  E-value: 3.89e-04
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*
gi 850990953    3 RKIAIYG-KGGIGKSTTQQNTAAAMSYFhGKNVMIHGCDPKADST 46
Cdd:pfam13614   2 KVIAIANqKGGVGKTTTSVNLAAALAKK-GKKVLLIDLDPQGNAT 45
ParA pfam10609
NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid ...
 3-248 2.45e-03

NUBPL iron-transfer P-loop NTPase; This family contains ATPases involved in plasmid partitioning. It also contains the cytosolic Fe-S cluster assembling factor NBP35 which is required for biogenesis and export of both ribosomal subunits.


Pssm-ID: 431392 [Multi-domain]  Cd Length: 246  Bit Score: 38.59  E-value: 2.45e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953    3 RKIAIY-GKGGIGKSTTQQNTAAAMSYfHGKNVMIhgCDpkADSTrlilgGKMQTTMMDTLRELGEVacTPDKVIETGFG 81
Cdd:pfam10609   4 HVIAVAsGKGGVGKSTVAVNLALALAR-LGYKVGL--LD--ADIY-----GPSIPRMLGLEGERPEQ--SDGGIIPVEAH 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953   82 GIKCVESG--GPEPGVGCAGRG--VITAIT--LMErhgVYEKDLDFVFFDV---LGDVvcggfAMPV-----RDGkaeeI 147
Cdd:pfam10609  72 GIKVMSIGflLPDEDDAVIWRGpmKSGAIKqfLTD---VDWGELDYLIIDLppgTGDE-----QLTLaqllpLTG----A 139

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 850990953  148 YIVASGEMMALYAANnicKGmVKYARQSGVRLGGIICN-SRNV---DGEKELL------EEFCERIGTQMIHFVPRD-NI 216
Cdd:pfam10609 140 VIVTTPQDVALLDVR---KA-IDMFKKVNVPVLGVVENmSYFVcphCGEETYIfgkgggEKLAEELGVPFLGEIPLDpDI 215

                         250       260       270
                  ....*....|....*....|....*....|..
gi 850990953  217 VQKAEfNKKSVIEFDPECNQSQEYRELARKII 248
Cdd:pfam10609 216 REAGD-EGKPFVLADPDSPAAKAFLKIADKVA 246
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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