|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
1-531 |
3.87e-173 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 502.00 E-value: 3.87e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVGDESHLTFFEMLGNFSFGGYFKEEAIKYAKEFFEST---GLKIE--YVTVFAGDEKTPPDEESYKI 75
Cdd:PRK01584 62 DVQKCLRTGDIDEVGDLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTSPdylNIPKDklYVTVFEGDEEIPRDEETASV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 76 WQSLGIKD--IQKAGREDNFWGPTGKEGPCGPTTEIYVNSalrqaqGKPP--------------VEVWNIVFNEYYCLPN 139
Cdd:PRK01584 142 WESLGIPKdrIFYLSREHNWWGPVGETGPCGPDTEIFVDT------GKPKcsvncrptcscgkyFEIWNNVFMQYNKDED 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 140 GSFEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVISLLPK---------DLHKARKRIVADHLRASVFLLAD--G 208
Cdd:PRK01584 216 GNYEELKRKCVDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKisgkiygqnEEDDRSIRIIADHIRAACFILGDpfV 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 209 VRPSNKERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQL 288
Cdd:PRK01584 296 VLPSNVGQGYVLRRLIRRSIRHAKKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEF 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 289 EKLILEYPPDKFgrvrdngelpivnmpkIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAE 368
Cdd:PRK01584 376 IKLIPNLGSSKI----------------IPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKKGAD 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 369 KKFGghgivggivgaptsvvGGRS--SDKIAKLHTATHLLLAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTVEEIQ 446
Cdd:PRK01584 440 KVFK----------------GGLAdhSYETTKLHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIK 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 447 KVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKYGEKVKVYSIGVpstgsgplFSREICGGPHVKNTGEIGHFKI 526
Cdd:PRK01584 504 KVEDIVNLQIKNDLSVKKEVMSLEEAREKGAMALFGEKYEDIVKVYEIDG--------FSKEVCGGPHVENTGELGTFKI 575
|
....*
gi 818609396 527 TKEES 531
Cdd:PRK01584 576 QKEQS 580
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
1-532 |
5.30e-164 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 488.03 E-value: 5.30e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTS----DIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFfeSTG-LKIE----YVTVFAGDEktppde 70
Cdd:COG0013 63 TSQKCVRTGgkhnDLENVGyTARHHTFFEMLGNFSFGDYFKEEAIAWAWEL--LTEvLGLPkerlWVTVYEDDD------ 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 71 ESYKIWQSL-GIKD--IQKAGREDNFWgPTGKEGPCGPTTEIYVNsalR--QAQGKPP----------VEVWNIVFNEYY 135
Cdd:COG0013 135 EAYDIWKKEiGVPEerIIRLGKKDNFW-EMGDTGPCGPCSEIFYD---RgpEYGGGPPgspgedgdryIEIWNLVFMQFN 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 136 CLPNGSFEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVI---------SLLPKDLHKARKRIVADHLRASVFLLA 206
Cdd:COG0013 211 RDEDGTLTPLPKKNIDTGMGLERIAAVLQGVHSNYETDLFRPLIeaaaeltgvKYGADEEDDVSLRVIADHIRAVAFLIA 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 207 DGVRPSNKERGYIlrrllrralayeytqnvpL------------------EVFESVLNEIIKKYRNFYSEFDQNKDEIVS 268
Cdd:COG0013 291 DGVLPSNEGRGYV------------------LrrilrravrhgrllgikePFLYKLVPVVVEEMGDAYPELKEKQELIEK 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 269 EFKKEKEQFLKVLPKGLKQLEKLIleyppdkfGRVRDNGElpivnmPKIPGDAIFDLYQSYG----LTPEIFKEelanRG 344
Cdd:COG0013 353 VLKAEEERFLRTLERGLKLLDEAI--------AKLKAAGG------KVLSGEDAFKLYDTYGfpldLTEEIARE----RG 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 345 LAYDEKQFELVKKKHQEISRAGAEKK----FGGHGIVGGIVGAPTS---------------------------------V 387
Cdd:COG0013 415 LTVDEEGFEAAMEEQRERARAAAKFSgdaaVDGVWRELLEEGGPTEfvgydtleaeakvlalvkdgelvdsakageeveV 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 388 V----------GGRSSDK---------------------------------------------------IAKLHTATHLL 406
Cdd:COG0013 495 VldrtpfyaesGGQVGDTgtiegdggvfevtdtqkppgglivhigkveegelkvgdtvtaqvdaerrraIARNHSATHLL 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 407 LAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTVEEIQKVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKYG 486
Cdd:COG0013 575 HAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKALGAMALFGEKYG 654
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 818609396 487 EKVKVYSIGvpstgsgpLFSREICGGPHVKNTGEIGHFKITKEESV 532
Cdd:COG0013 655 DEVRVVSIG--------DFSRELCGGTHVSRTGDIGLFKIVSESSV 692
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
3-532 |
2.83e-128 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 394.82 E-value: 2.83e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 3 QKCFRTSDIDEVGDES-HLTFFEMLGNFSFGGYFKEEAIKYAKEFFEST-GLKIE--YVTVFagdektPPDEESYKIWQS 78
Cdd:TIGR00344 60 QPCIRLNDLENVGRTArHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVlGLDKErlYVTVY------EDDEEAYKIWEK 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 79 LGIKD--IQKAGREDNFWgpTGKEGPCGPTTEIYVN-----SALRQAQGKPPVEVWNIVFNEYYCLPNGSFEKLPNPGVD 151
Cdd:TIGR00344 134 IGIPAdrIIKCDAKDNFW--DMGDGPCGPCTEIYYDfvggkPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNID 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 152 TGMGLERLVMVMQGKNNIFETDLFSEVISLL-----------------PKDLHKARK-RIVADHLRASVFLLADGVRPSN 213
Cdd:TIGR00344 212 TGMGLERFVAVLQGVPTNYDTDIFLPLIEKIeeitgvkydsnnagimdEKRVEDLRSlRVIADHTRAIAFMLADGVVPSN 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 214 KERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQLEKLIl 293
Cdd:TIGR00344 292 EGRGYVLRRLIRRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLL- 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 294 EYPPDKfgrvrdngelpivnmpKIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAE----- 368
Cdd:TIGR00344 371 KKTGKK----------------ELDGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQfqeqe 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 369 ------------------------KKFGGHGIVGGIVGAPTSVV------------GGRSSDK----------------- 395
Cdd:TIGR00344 435 ialvnvypateflgyddlefeakvIGLFDDGYLVEQALAGQSVYvildqtpfyaesGGQIGDTgyliandgkfrvvdvqk 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 396 ---------------------------------IAKLHTATHLLLAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTV 442
Cdd:TIGR00344 515 pngvvfhfgeveggslkvgdkviavidekrrfrIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTR 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 443 EEIQKVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKY--GEKVKVYSIGVpstgsgplFSREICGGPHVKNTGE 520
Cdd:TIGR00344 595 EELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGD--------FSVELCGGTHVRNTGE 666
|
650
....*....|..
gi 818609396 521 IGHFKITKEESV 532
Cdd:TIGR00344 667 IGLFKIVKESGI 678
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
1-370 |
1.79e-91 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 290.33 E-value: 1.79e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFF-ESTGLKIE--YVTVFAGDEktppdeESYKIW 76
Cdd:pfam01411 59 NSQKCIRAGDLENVGrTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLtKELGLPPErlYVTVFEWDD------EAGPIW 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 77 QSL-GIKD--IQKAGREDNFW--GPTGkegPCGPTTEIYVNSAL----RQAQGKPP------VEVWNIVFNEYYCLPNGS 141
Cdd:pfam01411 133 EKIvGGPEerILRFGDKDNFWemGDTG---PCGPCSEIDYDRGEeiggWDSGGTPTadddrfLEIWNLVFMQFNRENDGT 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 142 FEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVISLL---------PKDLHKARKRIVADHLRASVFLLADGVRPS 212
Cdd:pfam01411 210 LKPLPKKSIDTGMGLERLVAVLQDVRSNYDTDVFIPVIELIeeisgaryyTVDETDEAYRVIADHTRALTFALADGVVPS 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 213 NKERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQLEKLI 292
Cdd:pfam01411 290 NEGRGYVLRRILRRAVRHAKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI 369
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 818609396 293 LEYPPDKfgrvrdngelpivnmPKIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAEKK 370
Cdd:pfam01411 370 AKLKKGK---------------KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEK 432
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
1-166 |
5.27e-56 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 187.57 E-value: 5.27e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFF-ESTGLKIE--YVTVFAGDektppDEESYKIW 76
Cdd:cd00673 60 NSQKCIRAGDIDNVGkTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLtEVLGLPKDrlYVSVFEGD-----DEEEAIWW 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 77 QSLGIK--DIQKAGREDNFWGPTGkEGPCGPTTEIYV-------NSALRQAQGKPPVEVWNIVFNEYYCLPNGSFEKLPN 147
Cdd:cd00673 135 WKIGLPgiRIERIGFKDNFWEMGG-NGPCGPCSEIFYdrgeerdAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPK 213
|
170
....*....|....*....
gi 818609396 148 PGVDTGMGLERLVMVMQGK 166
Cdd:cd00673 214 KIVDTGMGLERLVWVLQGV 232
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
489-533 |
2.08e-14 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 67.02 E-value: 2.08e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 818609396 489 VKVYSIGVpstgsgplFSREICGGPHVKNTGEIGHFKITKEESVY 533
Cdd:smart00863 1 VRVVSIGD--------FSVELCGGTHVPNTGEIGAFKILSVSGAY 37
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK01584 |
PRK01584 |
alanyl-tRNA synthetase; Provisional |
1-531 |
3.87e-173 |
|
alanyl-tRNA synthetase; Provisional
Pssm-ID: 234962 [Multi-domain] Cd Length: 594 Bit Score: 502.00 E-value: 3.87e-173
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVGDESHLTFFEMLGNFSFGGYFKEEAIKYAKEFFEST---GLKIE--YVTVFAGDEKTPPDEESYKI 75
Cdd:PRK01584 62 DVQKCLRTGDIDEVGDLSHLTFFEMLGNWSLGAYFKEESIKYSFEFLTSPdylNIPKDklYVTVFEGDEEIPRDEETASV 141
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 76 WQSLGIKD--IQKAGREDNFWGPTGKEGPCGPTTEIYVNSalrqaqGKPP--------------VEVWNIVFNEYYCLPN 139
Cdd:PRK01584 142 WESLGIPKdrIFYLSREHNWWGPVGETGPCGPDTEIFVDT------GKPKcsvncrptcscgkyFEIWNNVFMQYNKDED 215
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 140 GSFEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVISLLPK---------DLHKARKRIVADHLRASVFLLAD--G 208
Cdd:PRK01584 216 GNYEELKRKCVDTGMGIERTIAFLQGKSSVYDTEAFTPIIKRIEKisgkiygqnEEDDRSIRIIADHIRAACFILGDpfV 295
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 209 VRPSNKERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQL 288
Cdd:PRK01584 296 VLPSNVGQGYVLRRLIRRSIRHAKKLGIESHFLADLVDSVEEIYGSFYPELTEKKDFIKEELNKEEEKFFKTLRKGEQEF 375
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 289 EKLILEYPPDKFgrvrdngelpivnmpkIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAE 368
Cdd:PRK01584 376 IKLIPNLGSSKI----------------IPGDIAFKLYDTYGFPYEITEELASEYGFTVDREGFDEHFKKHQKVSKKGAD 439
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 369 KKFGghgivggivgaptsvvGGRS--SDKIAKLHTATHLLLAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTVEEIQ 446
Cdd:PRK01584 440 KVFK----------------GGLAdhSYETTKLHTATHLLHKALRLVLGDHVRQKGSNITAERLRFDFSHPEKMTDDEIK 503
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 447 KVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKYGEKVKVYSIGVpstgsgplFSREICGGPHVKNTGEIGHFKI 526
Cdd:PRK01584 504 KVEDIVNLQIKNDLSVKKEVMSLEEAREKGAMALFGEKYEDIVKVYEIDG--------FSKEVCGGPHVENTGELGTFKI 575
|
....*
gi 818609396 527 TKEES 531
Cdd:PRK01584 576 QKEQS 580
|
|
| AlaS |
COG0013 |
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA ... |
1-532 |
5.30e-164 |
|
Alanyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Alanyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 439784 [Multi-domain] Cd Length: 880 Bit Score: 488.03 E-value: 5.30e-164
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTS----DIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFfeSTG-LKIE----YVTVFAGDEktppde 70
Cdd:COG0013 63 TSQKCVRTGgkhnDLENVGyTARHHTFFEMLGNFSFGDYFKEEAIAWAWEL--LTEvLGLPkerlWVTVYEDDD------ 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 71 ESYKIWQSL-GIKD--IQKAGREDNFWgPTGKEGPCGPTTEIYVNsalR--QAQGKPP----------VEVWNIVFNEYY 135
Cdd:COG0013 135 EAYDIWKKEiGVPEerIIRLGKKDNFW-EMGDTGPCGPCSEIFYD---RgpEYGGGPPgspgedgdryIEIWNLVFMQFN 210
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 136 CLPNGSFEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVI---------SLLPKDLHKARKRIVADHLRASVFLLA 206
Cdd:COG0013 211 RDEDGTLTPLPKKNIDTGMGLERIAAVLQGVHSNYETDLFRPLIeaaaeltgvKYGADEEDDVSLRVIADHIRAVAFLIA 290
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 207 DGVRPSNKERGYIlrrllrralayeytqnvpL------------------EVFESVLNEIIKKYRNFYSEFDQNKDEIVS 268
Cdd:COG0013 291 DGVLPSNEGRGYV------------------LrrilrravrhgrllgikePFLYKLVPVVVEEMGDAYPELKEKQELIEK 352
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 269 EFKKEKEQFLKVLPKGLKQLEKLIleyppdkfGRVRDNGElpivnmPKIPGDAIFDLYQSYG----LTPEIFKEelanRG 344
Cdd:COG0013 353 VLKAEEERFLRTLERGLKLLDEAI--------AKLKAAGG------KVLSGEDAFKLYDTYGfpldLTEEIARE----RG 414
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 345 LAYDEKQFELVKKKHQEISRAGAEKK----FGGHGIVGGIVGAPTS---------------------------------V 387
Cdd:COG0013 415 LTVDEEGFEAAMEEQRERARAAAKFSgdaaVDGVWRELLEEGGPTEfvgydtleaeakvlalvkdgelvdsakageeveV 494
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 388 V----------GGRSSDK---------------------------------------------------IAKLHTATHLL 406
Cdd:COG0013 495 VldrtpfyaesGGQVGDTgtiegdggvfevtdtqkppgglivhigkveegelkvgdtvtaqvdaerrraIARNHSATHLL 574
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 407 LAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTVEEIQKVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKYG 486
Cdd:COG0013 575 HAALREVLGEHVTQAGSLVAPDRLRFDFSHFEALTPEELAEIEDLVNEKIRENLPVETREMPLDEAKALGAMALFGEKYG 654
|
650 660 670 680
....*....|....*....|....*....|....*....|....*.
gi 818609396 487 EKVKVYSIGvpstgsgpLFSREICGGPHVKNTGEIGHFKITKEESV 532
Cdd:COG0013 655 DEVRVVSIG--------DFSRELCGGTHVSRTGDIGLFKIVSESSV 692
|
|
| alaS |
TIGR00344 |
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the ... |
3-532 |
2.83e-128 |
|
alanine--tRNA ligase; The model describes alanine--tRNA ligase. This enzyme catalyzes the reaction (tRNAala + L-alanine + ATP = L-alanyl-tRNAala + pyrophosphate + AMP). [Protein synthesis, tRNA aminoacylation]
Pssm-ID: 273026 [Multi-domain] Cd Length: 845 Bit Score: 394.82 E-value: 2.83e-128
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 3 QKCFRTSDIDEVGDES-HLTFFEMLGNFSFGGYFKEEAIKYAKEFFEST-GLKIE--YVTVFagdektPPDEESYKIWQS 78
Cdd:TIGR00344 60 QPCIRLNDLENVGRTArHHTLFEMLGNFSFGDYFKEEAIAFAWELLTEVlGLDKErlYVTVY------EDDEEAYKIWEK 133
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 79 LGIKD--IQKAGREDNFWgpTGKEGPCGPTTEIYVN-----SALRQAQGKPPVEVWNIVFNEYYCLPNGSFEKLPNPGVD 151
Cdd:TIGR00344 134 IGIPAdrIIKCDAKDNFW--DMGDGPCGPCTEIYYDfvggkPGEPLEENDRYLEVWNLVFMQFNRDPDGNYTPLPKKNID 211
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 152 TGMGLERLVMVMQGKNNIFETDLFSEVISLL-----------------PKDLHKARK-RIVADHLRASVFLLADGVRPSN 213
Cdd:TIGR00344 212 TGMGLERFVAVLQGVPTNYDTDIFLPLIEKIeeitgvkydsnnagimdEKRVEDLRSlRVIADHTRAIAFMLADGVVPSN 291
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 214 KERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQLEKLIl 293
Cdd:TIGR00344 292 EGRGYVLRRLIRRALRHGKKLGLKEAFLYKLVPTLIEVLGDYYPELKEKQEFVEQILELEEERFAKTLERGLRLFEKLL- 370
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 294 EYPPDKfgrvrdngelpivnmpKIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAE----- 368
Cdd:TIGR00344 371 KKTGKK----------------ELDGEDAFKLYDTYGFPVELTKEIAEERGLTVDMPGFEALMAEQRERSKQNSQfqeqe 434
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 369 ------------------------KKFGGHGIVGGIVGAPTSVV------------GGRSSDK----------------- 395
Cdd:TIGR00344 435 ialvnvypateflgyddlefeakvIGLFDDGYLVEQALAGQSVYvildqtpfyaesGGQIGDTgyliandgkfrvvdvqk 514
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 396 ---------------------------------IAKLHTATHLLLAALRKTLGKEIEQKGSDINDERARFDFNFPRKLTV 442
Cdd:TIGR00344 515 pngvvfhfgeveggslkvgdkviavidekrrfrIMRNHSATHLLHAALQKVLGNHVWQAGSLVSFKKLRFDFSHFRALTR 594
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 443 EEIQKVEELVNEKIREDLPVVCKEMTLEEAKQSGALGVFEHKY--GEKVKVYSIGVpstgsgplFSREICGGPHVKNTGE 520
Cdd:TIGR00344 595 EELEEIEDLANEQILANIPIKVIFMDLDEAKRKGAFALFGEKYvpGEKVRVVSVGD--------FSVELCGGTHVRNTGE 666
|
650
....*....|..
gi 818609396 521 IGHFKITKEESV 532
Cdd:TIGR00344 667 IGLFKIVKESGI 678
|
|
| PLN02900 |
PLN02900 |
alanyl-tRNA synthetase |
3-532 |
1.21e-120 |
|
alanyl-tRNA synthetase
Pssm-ID: 215487 [Multi-domain] Cd Length: 936 Bit Score: 377.05 E-value: 1.21e-120
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 3 QKCFRTS----DIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYA-----KEFfestGLKIE--YVTVFAGDEKTPPDE 70
Cdd:PLN02900 79 QKCIRAGgkhnDLDDVGkDTYHHTFFEMLGNWSFGDYFKKEAIGWAwelltKVY----GLPADrlYATYFGGDEKQAPDD 154
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 71 ESYKIW-QSLGIKDIQKAGREDNFW--GPTGkegPCGPTTEIYVN-------SALRQAQGKPPVEVWNIVFNEYYCLPNG 140
Cdd:PLN02900 155 EARAIWlDYLPEERVLPFGCKDNFWemGDTG---PCGPCSEIHYDrigerdaADLVNNDDPRFIEIWNLVFIQFNREADG 231
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 141 SFEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLF-------SEVISLLP---------KDLHKARKRIVADHLRASVFL 204
Cdd:PLN02900 232 SLKPLPAKHVDTGMGLERLASILQNKPSNYDTDLFmpifdaiQEATGARPyagkvgaedDDRVDMAYRVVADHIRTLSFA 311
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 205 LADGVRPSNKERGYILRRLLRRALAY-EYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPK 283
Cdd:PLN02900 312 IADGVVPSNEGRGYVLRRLLRRAVRYgRLLLGAEEGFFPALVEVVVELSGDVFPEVKKNEKRITEIIAEEELSFGKTLEK 391
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 284 GLKQLEKLIleyppdkfGRVRDNGElpivnmPKIPGDAIFDLYQSYGLTPEIfKEELA-NRGLAYDEKQFELVKKKHQEI 362
Cdd:PLN02900 392 GIEKFKKAL--------AAAKANGG------PVLSGKDAFLLYDTYGFPVDL-TELMAeERGVTVDMEGFEAAMEEARER 456
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 363 SRAG------------AEKKFGGHGIVGGI---------VGAPTSVV--------------------------------G 389
Cdd:PLN02900 457 SRAAhlkagggaielaAEATSWLQKQGVAAtddflkydwLSDHEAVVkailtgggfvesvsegdevgivldktsfyaesG 536
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 390 GRSSD---------------------------------------------------KIAKLHTATHLLLAALRKTLGKEI 418
Cdd:PLN02900 537 GQIGDtgvlegsggavvevsdvqkaggfvlhigtvtegsvsvgdavtckvdydrrrRIAPNHTATHLLNSALKEVLGDHV 616
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 419 EQKGSDINDERARFDFNFPRKLTVEEIQKVEELVNEKIREDLPVVCKEMTLEEAKQ-SGALGVFEHKYGEKVKVYSIgvp 497
Cdd:PLN02900 617 DQKGSLVAFEKLRFDFSHGKPMTPEELREVESLVNEWIGDALPVEAKEMPLADAKRiNGLRAVFGEKYPDPVRVVSV--- 693
|
650 660 670
....*....|....*....|....*....|....*
gi 818609396 498 stgsGPLFSREICGGPHVKNTGEIGHFKITKEESV 532
Cdd:PLN02900 694 ----GGVYSMELCGGTHVSNTAEAEAFKLLSEEGI 724
|
|
| tRNA-synt_2c |
pfam01411 |
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be ... |
1-370 |
1.79e-91 |
|
tRNA synthetases class II (A); Other tRNA synthetase sub-families are too dissimilar to be included. This family includes only alanyl-tRNA synthetases.
Pssm-ID: 279719 [Multi-domain] Cd Length: 548 Bit Score: 290.33 E-value: 1.79e-91
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFF-ESTGLKIE--YVTVFAGDEktppdeESYKIW 76
Cdd:pfam01411 59 NSQKCIRAGDLENVGrTGRHHTFFEMLGNFSFGDYFKEEAIEYAWELLtKELGLPPErlYVTVFEWDD------EAGPIW 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 77 QSL-GIKD--IQKAGREDNFW--GPTGkegPCGPTTEIYVNSAL----RQAQGKPP------VEVWNIVFNEYYCLPNGS 141
Cdd:pfam01411 133 EKIvGGPEerILRFGDKDNFWemGDTG---PCGPCSEIDYDRGEeiggWDSGGTPTadddrfLEIWNLVFMQFNRENDGT 209
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 142 FEKLPNPGVDTGMGLERLVMVMQGKNNIFETDLFSEVISLL---------PKDLHKARKRIVADHLRASVFLLADGVRPS 212
Cdd:pfam01411 210 LKPLPKKSIDTGMGLERLVAVLQDVRSNYDTDVFIPVIELIeeisgaryyTVDETDEAYRVIADHTRALTFALADGVVPS 289
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 213 NKERGYILRRLLRRALAYEYTQNVPLEVFESVLNEIIKKYRNFYSEFDQNKDEIVSEFKKEKEQFLKVLPKGLKQLEKLI 292
Cdd:pfam01411 290 NEGRGYVLRRILRRAVRHAKKLGLKEPFLYDLVPTVVEVLGDAYPELKEDEDFIQEILELEEERFAKTLERGLRLLERLI 369
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 818609396 293 LEYPPDKfgrvrdngelpivnmPKIPGDAIFDLYQSYGLTPEIFKEELANRGLAYDEKQFELVKKKHQEISRAGAEKK 370
Cdd:pfam01411 370 AKLKKGK---------------KTLPGEDAFKLYDTYGFPVDLTKEIAEERGLKVDMPGFEYAMVEQRERSKQAVKEK 432
|
|
| AlaRS_core |
cd00673 |
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is ... |
1-166 |
5.27e-56 |
|
Alanyl-tRNA synthetase (AlaRS) class II core catalytic domain. AlaRS is a homodimer. It is responsible for the attachment of alanine to the 3' OH group of ribose of the appropriate tRNA. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. Class II assignment is based upon its predicted structure and the presence of three characteristic sequence motifs.
Pssm-ID: 238360 [Multi-domain] Cd Length: 232 Bit Score: 187.57 E-value: 5.27e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 1 SIQKCFRTSDIDEVG-DESHLTFFEMLGNFSFGGYFKEEAIKYAKEFF-ESTGLKIE--YVTVFAGDektppDEESYKIW 76
Cdd:cd00673 60 NSQKCIRAGDIDNVGkTGRHHTFFEMLGNFSFGDYFKEEAIAFAWELLtEVLGLPKDrlYVSVFEGD-----DEEEAIWW 134
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 77 QSLGIK--DIQKAGREDNFWGPTGkEGPCGPTTEIYV-------NSALRQAQGKPPVEVWNIVFNEYYCLPNGSFEKLPN 147
Cdd:cd00673 135 WKIGLPgiRIERIGFKDNFWEMGG-NGPCGPCSEIFYdrgeerdAASLPNEDDDRYLEIWNLVFMQYNRDADGTYRPLPK 213
|
170
....*....|....*....
gi 818609396 148 PGVDTGMGLERLVMVMQGK 166
Cdd:cd00673 214 KIVDTGMGLERLVWVLQGV 232
|
|
| AlaX |
COG2872 |
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis] ... |
398-537 |
4.92e-23 |
|
Ser-tRNA(Ala) deacylase AlaX (editing enzyme) [Translation, ribosomal structure and biogenesis];
Pssm-ID: 442119 [Multi-domain] Cd Length: 238 Bit Score: 97.96 E-value: 4.92e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 398 KLHTATHLLLAALRKTLGKEIeqKGSDINDERARFDFNFPRkLTVEEIQKVEELVNEKIREDLPVVCKEMTLEEAkqsga 477
Cdd:COG2872 98 RLHTALHLLSAVVYREYGAPV--TGGQIGEDRARIDFDLPE-FDEEDLEEIEAEANELIAADLPVRIYWITREEL----- 169
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 818609396 478 lgvfeHKYGEKVKvYSIGVPSTGSGPLfsR--EI-------CGGPHVKNTGEIGHFKITKEESvylKSK 537
Cdd:COG2872 170 -----EAIPGLVR-TMSVLPPPGVGRV--RivEIggvdlqpCGGTHVANTGEIGRIKITKIEK---KGK 227
|
|
| tRNA_SAD |
smart00863 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of ... |
489-533 |
2.08e-14 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active form of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this SAD domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 197931 [Multi-domain] Cd Length: 43 Bit Score: 67.02 E-value: 2.08e-14
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 818609396 489 VKVYSIGVpstgsgplFSREICGGPHVKNTGEIGHFKITKEESVY 533
Cdd:smart00863 1 VRVVSIGD--------FSVELCGGTHVPNTGEIGAFKILSVSGAY 37
|
|
| tRNA_SAD |
pfam07973 |
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of ... |
489-532 |
1.86e-12 |
|
Threonyl and Alanyl tRNA synthetase second additional domain; The catalytically active from of threonyl/alanyl tRNA synthetase is a dimer. Within the tRNA synthetase class II dimer, the bound tRNA interacts with both monomers making specific interactions with the catalytic domain, the C-terminal domain, and this domain (the second additional domain). The second additional domain is comprised of a pair of perpendicularly orientated antiparallel beta sheets, of four and three strands, respectively, that surround a central alpha helix that forms the core of the domain.
Pssm-ID: 429764 [Multi-domain] Cd Length: 43 Bit Score: 61.69 E-value: 1.86e-12
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 818609396 489 VKVYSIGVpstgsgplFSREICGGPHVKNTGEIGHFKITKEESV 532
Cdd:pfam07973 1 VRVVSIGD--------FDVDLCGGTHVPNTGEIGAFKILKGESK 36
|
|
| ThrS |
COG0441 |
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA ... |
400-528 |
2.82e-11 |
|
Threonyl-tRNA synthetase [Translation, ribosomal structure and biogenesis]; Threonyl-tRNA synthetase is part of the Pathway/BioSystem: Aminoacyl-tRNA synthetases
Pssm-ID: 440210 [Multi-domain] Cd Length: 639 Bit Score: 66.21 E-value: 2.82e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 400 HTATHLLLAALRK-------TLGKEIEQkGsdinderarF--DFNFPRKLTVEEIQKVEELVNEKIREDLPVVCKEMTLE 470
Cdd:COG0441 73 HSAAHLLAQAVKRlypdaklTIGPVIEN-G---------FyyDFDLERPFTPEDLEKIEKEMKEIIKEDLPIEREEVSRE 142
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 818609396 471 EAKQsgalgVFEHK---Y----------GEKVKVYSIGvpstgsgplfsrE---ICGGPHVKNTGEIGHFKITK 528
Cdd:COG0441 143 EAIE-----LFKEKgepYkveliedipeDEEISLYRQG------------EfvdLCRGPHVPSTGKIKAFKLLS 199
|
|
| PRK12444 |
PRK12444 |
threonyl-tRNA synthetase; Reviewed |
400-533 |
1.80e-06 |
|
threonyl-tRNA synthetase; Reviewed
Pssm-ID: 183530 [Multi-domain] Cd Length: 639 Bit Score: 50.52 E-value: 1.80e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 400 HTATHLLLAALRKTLGKEIEQKGSDINDErARFDFNFPRKLTVEEIQKVEELVNEKIREDLPVVCKEMTLEEAKQsgalg 479
Cdd:PRK12444 77 HSAAHILAQAVKRLYGDVNLGVGPVIENG-FYYDMDLPSSVNVEDLRKIEKEMKKIINENIKIERVEVSREEAAK----- 150
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 818609396 480 VFEHKyGEKVKVYSI-GVPSTGSGPLFSR----EICGGPHVKNTGEIGHFKITKEESVY 533
Cdd:PRK12444 151 LFQEM-NDRLKLELLeAIPSGESITLYKQgefvDLCRGPHLPSTGYLKAFQLTHVSGAY 208
|
|
| PLN02837 |
PLN02837 |
threonine-tRNA ligase |
392-532 |
7.72e-05 |
|
threonine-tRNA ligase
Pssm-ID: 215450 [Multi-domain] Cd Length: 614 Bit Score: 45.27 E-value: 7.72e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 392 SSDKIAKL-HTATHLLLAALRK-------TLGKEIEqKGsdinderarFDFNFPRK-LTVEEIQKVEELVNEKIREDLPV 462
Cdd:PLN02837 39 SSEKLLKIrHTCAHVMAMAVQKlfpdakvTIGPWIE-NG---------FYYDFDMEpLTDKDLKRIKKEMDRIISRNLPL 108
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 818609396 463 VCKEMTLEEAK-------QSGALGVFEHKYGEKVKVYSIGVPSTgsgplfsrEICGGPHVKNTGEIGHfKITKEESV 532
Cdd:PLN02837 109 VREEVSREEAQkrimainEPYKLEILEGIKEEPITIYHIGEEWW--------DLCAGPHVERTGKINK-KAVELESV 176
|
|
| PLN02961 |
PLN02961 |
alanine-tRNA ligase |
397-527 |
3.81e-04 |
|
alanine-tRNA ligase
Pssm-ID: 178546 [Multi-domain] Cd Length: 223 Bit Score: 41.99 E-value: 3.81e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 397 AKLHTATHLLLAALRKT-LGKEIEQKGsdinderarfdFNFPRKLTVE--------EIQKV----EELVNEKIREDLPVV 463
Cdd:PLN02961 83 SRLHSAGHLLDVCMARVgLGPLEPGKG-----------YHFPDGPFVEykgkipqgELDSKqdelEAEANELIAEGGKVS 151
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 818609396 464 CKEMTLEEAKQ--SGALGVFEHKygeKVKVYSIGVPSTGSGPlfsreiCGGPHVKNTGEIGHFKIT 527
Cdd:PLN02961 152 AAVLPYDEAAElcGGSLPDYIAK---DSTPRIVKIGDSPGCP------CGGTHVADVSEITSVKVT 208
|
|
| class_II_aaRS-like_core |
cd00768 |
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA ... |
2-159 |
7.30e-04 |
|
Class II tRNA amino-acyl synthetase-like catalytic core domain. Class II amino acyl-tRNA synthetases (aaRS) share a common fold and generally attach an amino acid to the 3' OH of ribose of the appropriate tRNA. PheRS is an exception in that it attaches the amino acid at the 2'-OH group, like class I aaRSs. These enzymes are usually homodimers. This domain is primarily responsible for ATP-dependent formation of the enzyme bound aminoacyl-adenylate. The substrate specificity of this reaction is further determined by additional domains. Intererestingly, this domain is also found is asparagine synthase A (AsnA), in the accessory subunit of mitochondrial polymerase gamma and in the bacterial ATP phosphoribosyltransferase regulatory subunit HisZ.
Pssm-ID: 238391 [Multi-domain] Cd Length: 211 Bit Score: 40.95 E-value: 7.30e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 2 IQKCFRtsdiDEVGDES--HLTFFEMLGNFSFGGYFKEeaikyAKEFFEStglkIEYVtvfagdektppdeesYKIWQSL 79
Cdd:cd00768 81 IGPAFR----NEGGRRGlrRVREFTQLEGEVFGEDGEE-----ASEFEEL----IELT---------------EELLRAL 132
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 818609396 80 GIKDiqKAGREDNFWGPTgKEGPCGPTTEIYVNSALRQAqgkppVEVWNIVF---------NEYYCLPNGSFEKLpnPGV 150
Cdd:cd00768 133 GIKL--DIVFVEKTPGEF-SPGGAGPGFEIEVDHPEGRG-----LEIGSGGYrqdeqaraaDLYFLDEALEYRYP--PTI 202
|
....*....
gi 818609396 151 DTGMGLERL 159
Cdd:cd00768 203 GFGLGLERL 211
|
|
| |
