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Conserved domains on  [gi|81622028|sp|Q9HUB1|]
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RecName: Full=Methyl-accepting chemotaxis protein McpK; AltName: Full=Methyl-accepting chemotaxis protein K

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
113-647 1.21e-85

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 278.06  E-value: 1.21e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 113 IEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAGDPQALQRSRAVADLHQQLLMVRYQ--VR 190
Cdd:COG0840   1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLalVV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 191 GYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMAR 270
Cdd:COG0840  81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 271 AGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDE 350
Cdd:COG0840 161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVR----IDVDSKDE 236

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 351 LGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQ 430
Cdd:COG0840 237 IGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAE 316

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 431 AARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGR 510
Cdd:COG0840 317 LAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGR 396

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 511 GFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIA 590
Cdd:COG0840 397 GFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIA 476

                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 81622028 591 TAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAASSGELARLGTQLQAQVGRFRL 647
Cdd:COG0840 477 AASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
113-647 1.21e-85

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 278.06  E-value: 1.21e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 113 IEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAGDPQALQRSRAVADLHQQLLMVRYQ--VR 190
Cdd:COG0840   1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLalVV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 191 GYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMAR 270
Cdd:COG0840  81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 271 AGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDE 350
Cdd:COG0840 161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVR----IDVDSKDE 236

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 351 LGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQ 430
Cdd:COG0840 237 IGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAE 316

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 431 AARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGR 510
Cdd:COG0840 317 LAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGR 396

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 511 GFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIA 590
Cdd:COG0840 397 GFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIA 476

                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 81622028 591 TAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAASSGELARLGTQLQAQVGRFRL 647
Cdd:COG0840 477 AASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 385-646 3.81e-66

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 217.92  E-value: 3.81e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    385 ELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSS 464
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    465 EAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGA 544
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    545 GEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQT 624
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 81622028    625 AASSGELARLGTQLQAQVGRFR 646
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 412-607 9.72e-50

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 171.65  E-value: 9.72e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 412 HEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQT 491
Cdd:cd11386   1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 492 NLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAA 571
Cdd:cd11386  81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 81622028 572 LDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSV 607
Cdd:cd11386 161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAV 196
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
307-647 3.21e-38

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 149.33  E-value: 3.21e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  307 VAGW-AINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEE 385
Cdd:PRK15041 208 FAVWfGIKASLVAPMNRLIDSIRHIAGGDLVKP----IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASE 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  386 LSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVtrierlasemdvssE 465
Cdd:PRK15041 284 IATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVV--------------Q 349

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  466 AMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQrlqqgag 545
Cdd:PRK15041 350 TMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIE------- 422

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  546 EAAERLENSRSLTAStvelarrAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTA 625
Cdd:PRK15041 423 DSVGKVDVGSTLVES-------AGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESA 495

                        330       340
                 ....*....|....*....|..
gi 81622028  626 ASSGELARLGTQLQAQVGRFRL 647
Cdd:PRK15041 496 AAAAALEEQASRLTEAVAVFRI 517
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 429-613 2.37e-37

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 136.79  E-value: 2.37e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   429 SQAARQADEEARQGDAVVDQAVTrierlasemdvsseAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDA 508
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVG--------------QMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   509 GRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQ 588
Cdd:pfam00015  67 GRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQE 146

                         170       180
                  ....*....|....*....|....*
gi 81622028   589 IATAAEQQSTVAEEINRSVLSVRDV 613
Cdd:pfam00015 147 IAAASDEQSAGIDQVNQAVARMDQV 171
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
113-647 1.21e-85

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 278.06  E-value: 1.21e-85
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 113 IEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAGDPQALQRSRAVADLHQQLLMVRYQ--VR 190
Cdd:COG0840   1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLalVV 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 191 GYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMAR 270
Cdd:COG0840  81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 271 AGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDE 350
Cdd:COG0840 161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVR----IDVDSKDE 236

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 351 LGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQ 430
Cdd:COG0840 237 IGQLADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAE 316

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 431 AARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGR 510
Cdd:COG0840 317 LAEEASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGR 396

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 511 GFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIA 590
Cdd:COG0840 397 GFAVVADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIA 476

                       490       500       510       520       530
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 81622028 591 TAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAASSGELARLGTQLQAQVGRFRL 647
Cdd:COG0840 477 AASEEQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 385-646 3.81e-66

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 217.92  E-value: 3.81e-66
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    385 ELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSS 464
Cdd:smart00283   1 DVSEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAV 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    465 EAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGA 544
Cdd:smart00283  81 SAVEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEET 160

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    545 GEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQT 624
Cdd:smart00283 161 NEAVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEI 240

                          250       260
                   ....*....|....*....|..
gi 81622028    625 AASSGELARLGTQLQAQVGRFR 646
Cdd:smart00283 241 SAAAEELSGLAEELDELVERFK 262
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 412-607 9.72e-50

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 171.65  E-value: 9.72e-50
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 412 HEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQT 491
Cdd:cd11386   1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 492 NLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAA 571
Cdd:cd11386  81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                       170       180       190
                ....*....|....*....|....*....|....*.
gi 81622028 572 LDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSV 607
Cdd:cd11386 161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAV 196
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
307-647 3.21e-38

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 149.33  E-value: 3.21e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  307 VAGW-AINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEE 385
Cdd:PRK15041 208 FAVWfGIKASLVAPMNRLIDSIRHIAGGDLVKP----IEVDGSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASE 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  386 LSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVtrierlasemdvssE 465
Cdd:PRK15041 284 IATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENARQASHLALSASETAQRGGKVVDNVV--------------Q 349

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  466 AMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQrlqqgag 545
Cdd:PRK15041 350 TMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLAQRSAQAAREIKSLIE------- 422

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  546 EAAERLENSRSLTAStvelarrAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTA 625
Cdd:PRK15041 423 DSVGKVDVGSTLVES-------AGETMAEIVSAVTRVTDIMGEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESA 495

                        330       340
                 ....*....|....*....|..
gi 81622028  626 ASSGELARLGTQLQAQVGRFRL 647
Cdd:PRK15041 496 AAAAALEEQASRLTEAVAVFRI 517
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 429-613 2.37e-37

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 136.79  E-value: 2.37e-37
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   429 SQAARQADEEARQGDAVVDQAVTrierlasemdvsseAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDA 508
Cdd:pfam00015   1 SDLAQLASEEAQDGGKEVANVVG--------------QMEQIAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQ 66

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   509 GRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQ 588
Cdd:pfam00015  67 GRGFAVVADEVRKLAERSAQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQE 146

                         170       180
                  ....*....|....*....|....*
gi 81622028   589 IATAAEQQSTVAEEINRSVLSVRDV 613
Cdd:pfam00015 147 IAAASDEQSAGIDQVNQAVARMDQV 171
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 307-647 9.98e-37

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 144.76  E-value: 9.98e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  307 VAGWAINRQIVRPLDEALAQAEAIAAGDLgkrpQNPLTLQRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEEL 386
Cdd:PRK15048 207 VAWYGIRRMLLTPLAKIIAHIREIAGGNL----ANTLTIDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREI 282

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  387 SAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVtrierlasemdvssEA 466
Cdd:PRK15048 283 AAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADNARQASQLAQSASDTAQHGGKVVDGVV--------------KT 348

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  467 MARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIqrlqqgage 546
Cdd:PRK15048 349 MHEIADSSKKIADIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKALI--------- 419

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  547 aaerlENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAA 626
Cdd:PRK15048 420 -----EDSVSRVDTGSVLVESAGETMNNIVNAVTRVTDIMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAA 494

                        330       340
                 ....*....|....*....|.
gi 81622028  627 SSGELARLGTQLQAQVGRFRL 647
Cdd:PRK15048 495 AAAALEEQASRLTQAVSAFRL 515
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
310-647 6.19e-34

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 136.35  E-value: 6.19e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  310 WAINRQIVRPLDEALAQAEAIAAGDLGKrpqnPLTLQRRDELGQLQRVMQRMGDSLRELVGRISDG-------VSQLASS 382
Cdd:PRK09793 208 WWTRKMIVQPLAIIGSHFDSIAAGNLAR----PIAVYGRNEITAIFASLKTMQQALRGTVSDVRKGsqemhigIAEIVAG 283

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  383 AEELSAVTEQtragvnsQKVETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEmdv 462
Cdd:PRK09793 284 NNDLSSRTEQ-------QAASLAQTAASMEQLTATVGQNADNARQASELAKNAATTAQAGGVQVSTMTHTMQEIATS--- 353

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  463 sseamarlkneSEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQ---- 538
Cdd:PRK09793 354 -----------SQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAGEVRNLASRSAQAAKEIKGLIEesvn 422

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  539 RLQQGAGeaaerlensrsltastveLARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSA 618
Cdd:PRK09793 423 RVQQGSK------------------LVNNAAATMTDIVSSVTRVNDIMGEIASASEEQRRGIEQVAQAVSQMDQVTQQNA 484

                        330       340
                 ....*....|....*....|....*....
gi 81622028  619 AASEQTAASSGELARLGTQLQAQVGRFRL 647
Cdd:PRK09793 485 SLVEEAAVATEQLANQADHLSSRVAVFTL 513
HBM pfam16591
Helical bimodular sensor domain; The HBM sensor domain has been identified primarily in ...
 47-287 2.43e-29

Helical bimodular sensor domain; The HBM sensor domain has been identified primarily in bacterial chemoreceptors but is also present on histidine kinases. characteriztic features of this domain are its size of approximately 250 amino acids and its location in the bacterial periplasm. The McpS chemoreceptor of Pseudomonas putida KT2440 was found to possess an HBM sensor domain and its 3D structure in complex with physiologically relevant ligands has been reported. This domain is composed of 2 long and 4 short helices that form two modules each composed of a 4-helix bundle. The McpS chemoreceptor mediates chemotaxis towards a number of organic acids. Both modules of the McpS HBM domain contain a ligand binding site. Chemo-attractants binds to each of these sites and their binding was shown to trigger a chemotactic response. This domain is primarily found in different proteobacteria but also in archaea. Interestingly, amino acids in both ligand binding sites showed a high degree of conservation suggesting that members of this family sense similar ligands. This domain recognizes Multiple TCA cycle intermediates, citrate and alpha-ketoglutarate (Matilla et.al., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 435446 [Multi-domain]  Cd Length: 246  Bit Score: 116.73  E-value: 2.43e-29
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028    47 SEQLAEVASLMEQTQQAEQGRLAFE-AGSDPRQAEQVRQTLAGMLQRLQALRDSELDPAALAH---QVEAIEAYRKAFDD 122
Cdd:pfam16591   5 SDRMTDISQLNDTLTDLRIARLQYMlSNGDATAAQAVQKKLDELKQQLQQLKTTFTSPENVRLlqeQLQLIQAYRKSFNE 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   123 LAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQqagDPQALQRSRAVADLHQQLLMVRYQVRGYVFERSDKAEQ 202
Cdd:pfam16591  85 LRAAYESRNASRQVMDSAAERALEAIDQLEAEVLQTPEA---DSRRAAQYQAISELKRQVQMARYQVRGYTFTPNEDSEQ 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028   203 AAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMARAGRTLTEAGRQL 282
Cdd:pfam16591 162 AAYQQLDAALASLDQLRQALAGDPGAALQQLTSALQGYRDALDTFKAAVAAIEQARQEMTSQGDEIVRISDELYQNQTEQ 241


                  ....*
gi 81622028   283 RESTA 287
Cdd:pfam16591 242 RDSEA 246
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
83-642 5.57e-05

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 46.26  E-value: 5.57e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  83 RQTLAGMLQRLQALRDSELDPAALAHQVEAIEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQ 162
Cdd:COG2770   3 LLLLALLLLLLLLLLLLLLAGALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLL 82

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 163 AGDPQALQRSRAVADLHQQLLMVRYQVRGYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRG 242
Cdd:COG2770  83 SLVALAALLLALLLLLLLALLLLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAA 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 243 GIEQFRAGVIRTRQAQQAMQSSTQDMARAGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRPLDE 322
Cdd:COG2770 163 ALALALGAGELLLLADLAAAIAALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRR 242

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 323 ALAQAEAIAAGDLGKRpqnpLTLQRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKV 402
Cdd:COG2770 243 LAEAARRIAAGDLDVR----IPVSRKDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLL 318

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 403 ETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLD 482
Cdd:COG2770 319 ALLLLAAAALLLELLLLLLLALLLLLLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAAL 398

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 483 VIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTV 562
Cdd:COG2770 399 AAALLLLELALEELVLALLALALLALAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAAL 478

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 563 ELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQTAASSGELARLGTQLQAQV 642
Cdd:COG2770 479 LLLAALGALELLLLEEEEEAGAAAEELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLAL 558
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 346-573 6.70e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 6.70e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 346 QRRDELGQLQRVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNA 425
Cdd:COG1196 271 ELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAE 350

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 426 ELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARA 505
Cdd:COG1196 351 EELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEAL 430

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 81622028 506 GDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSLTASTVELARRAGAALD 573
Cdd:COG1196 431 AELEEEEEEEEEALEEAAEEEAELEEEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLE 498
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 77-635 8.01e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 46.08  E-value: 8.01e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  77 RQAEQVRQTLAGMLQRLQALRDSELdpAALAHQVEAIEAYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMD 156
Cdd:COG1196 235 RELEAELEELEAELEELEAELEELE--AELAELEAELEELRLELEELELELEEAQAEEYELLAELARLEQDIARLEERRR 312

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 157 ASLAQQAGDPQALQRSRAVADLHQQLLmVRYQVRGYVFERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGS 236
Cdd:COG1196 313 ELEERLEELEEELAELEEELEELEEEL-EELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAEELLEA 391

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 237 LQGyrggIEQFRAgviRTRQAQQAMQSSTQDMARAGRTLTEAGRQLRESTASRDRASLWLIAALALAFGCVAgwAINRQI 316
Cdd:COG1196 392 LRA----AAELAA---QLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEE--EEEALL 462

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 317 VRPLDEALAQAEAIAAGDLGKRPQNPLTLQRRDELGQLQRVMQRMGDSLRELV----GRISDGVSQLASSAEELSAVTEQ 392
Cdd:COG1196 463 ELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLlaglRGLAGAVAVLIGVEAAYEAALEA 542

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 393 TRAGVNSQKV-ETDQVATAMHEMAATVQDVARNAELASQAARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLK 471
Cdd:COG1196 543 ALAAALQNIVvEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVLGDTL 622

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 472 NESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERL 551
Cdd:COG1196 623 LGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAE 702

                       490       500       510       520       530       540       550       560
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 552 ENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQSAAASEQtaassgEL 631
Cdd:COG1196 703 EEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELLEEEELLEEEALEELPEPPDLEELERELERLER------EI 776


                ....
gi 81622028 632 ARLG 635
Cdd:COG1196 777 EALG 780
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-557 8.88e-05

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 45.70  E-value: 8.88e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  38 RTLTHQTALSEQLAEVASLMEQTQQAEQGRLaFEAGSDPRQAEQVRQTLAGMLQRLQA--LRDSELDPAALAHQVEAIEA 115
Cdd:COG1196 260 AELAELEAELEELRLELEELELELEEAQAEE-YELLAELARLEQDIARLEERRRELEErlEELEEELAELEEELEELEEE 338

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 116 YRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAgdpQALQRSRAVADLHQQLlmvryqvrgyvfE 195
Cdd:COG1196 339 LEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEELEELAE---ELLEALRAAAELAAQL------------E 403

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 196 RSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMgslqgyrgGIEQFRAGVIRTRQAQQAMQSSTQDMARAGRTL 275
Cdd:COG1196 404 ELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEE--------ALEEAAEEEAELEEEEEALLELLAELLEEAALL 475

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 276 TEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIvrpldealaQAEAIAAGDLGKRPQNPLTLQRRDELGQLQ 355
Cdd:COG1196 476 EAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAALLL---------AGLRGLAGAVAVLIGVEAAYEAALEAALAA 546

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 356 RVMQRMGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAgvnsqKVETDQVATAMHEMAATVQDVARNAELASQAARQA 435
Cdd:COG1196 547 ALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARA-----ALAAALARGAIGAAVDLVASDLREADARYYVLGDT 621

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 436 DEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGsvldvIKSVAEQTNLLALNAAIEAARAGDAGRGFAVV 515
Cdd:COG1196 622 LLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSLTG-----GSRRELLAALLEAEAELEELAERLAEEELELE 696

                       490       500       510       520
                ....*....|....*....|....*....|....*....|..
gi 81622028 516 ADEVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLENSRSL 557
Cdd:COG1196 697 EALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELL 738
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 43-553 7.63e-04

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.62  E-value: 7.63e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  43 QTALSEQLAEVASLMEQTQQAEQGRLAFEAGSdpRQAEQVRQTLAgmLQRLQALRDSELDPAALAHQVEAIEAYRKAFDD 122
Cdd:COG1196 280 ELELEEAQAEEYELLAELARLEQDIARLEERR--RELEERLEELE--EELAELEEELEELEEELEELEEELEEAEEELEE 355

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 123 LAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAGDPQALQRSRAVADLHQQLLMVRYQVRGYVFERSDKAEQ 202
Cdd:COG1196 356 AEAELAEAEEALLEAEAELAEAEEELEELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEE 435

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 203 AAFAAFDALRQAATTLRGQLpgEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQDMARAGRTLTEAGRQL 282
Cdd:COG1196 436 EEEEEEEALEEAAEEEAELE--EEEEALLELLAELLEEAALLEAALAELLEELAEAAARLLLLLEAEADYEGFLEGVKAA 513

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 283 RESTASRD-----RASLWLIAALALAFGCVAGWAINRQIVRPLDEALAQAEAIAAGDLGKRPQNPLTLQRRDELGQLQRv 357
Cdd:COG1196 514 LLLAGLRGlagavAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKAAKAGRATFLPLDKIRARAALAAAL- 592

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 358 mqrmgdslreLVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQAARQADE 437
Cdd:COG1196 593 ----------ARGAIGAAVDLVASDLREADARYYVLGDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEGEGGSAGGSL 662

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 438 EARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVAD 517
Cdd:COG1196 663 TGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAEREELLEELL 742

                       490       500       510
                ....*....|....*....|....*....|....*.
gi 81622028 518 EVRGLAQRTQQSTAEIEGLIQRLQQGAGEAAERLEN 553
Cdd:COG1196 743 EEEELLEEEALEELPEPPDLEELERELERLEREIEA 778
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 38-480 1.24e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 42.23  E-value: 1.24e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028  38 RTLTHQTALSEQLAEVASLMEQTQQAEQGRLAFEAGSDPRQAE--QVRQTLAGMLQRLQALRDSELDPA-ALAHQVEAIE 114
Cdd:COG1196 338 ELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEleELAEELLEALRAAAELAAQLEELEeAEEALLERLE 417

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 115 AYRKAFDDLAAADQQRSAARGVLVGTAQQALDSFARLEELMDASLAQQAgDPQALQRSRAVADLHQQLLMVRYQVRGYVF 194
Cdd:COG1196 418 RLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEALLELLA-ELLEEAALLEAALAELLEELAEAAARLLLL 496

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 195 ERSDKAEQAAFAAFDALRQAATTLRGQLPGEADAALEQAMGSLQGYRGGIEQFRAGVIRTRQAQQAMQSSTQdmARAGRT 274
Cdd:COG1196 497 LEAEADYEGFLEGVKAALLLAGLRGLAGAVAVLIGVEAAYEAALEAALAAALQNIVVEDDEVAAAAIEYLKA--AKAGRA 574

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 275 LTEAGRQLRESTASRDRASLWLIAALALAFGCVAGWAINRQIVRpLDEALAQAEAIAAGDLGKRPQNPLTLQRRDELGQL 354
Cdd:COG1196 575 TFLPLDKIRARAALAAALARGAIGAAVDLVASDLREADARYYVL-GDTLLGRTLVAARLEAALRRAVTLAGRLREVTLEG 653

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 355 QRVMQR---MGDSLRELVGRISDGVSQLASSAEELSAVTEQTRAGVNSQKVETDQVATAMHEMAATVQDVARNAELASQA 431
Cdd:COG1196 654 EGGSAGgslTGGSRRELLAALLEAEAELEELAERLAEEELELEEALLAEEEEERELAEAEEERLEEELEEEALEEQLEAE 733

                       410       420       430       440
                ....*....|....*....|....*....|....*....|....*....
gi 81622028 432 ARQADEEARQGDAVVDQAVTRIERLASEMDVSSEAMARLKNESEQIGSV 480
Cdd:COG1196 734 REELLEELLEEEELLEEEALEELPEPPDLEELERELERLEREIEALGPV 782
Smc COG1196
Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning]; ...
 378-644 1.58e-03

Chromosome segregation ATPase Smc [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 440809 [Multi-domain]  Cd Length: 983  Bit Score: 41.85  E-value: 1.58e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 378 QLASSAEELSAVTEQTRAGVNSQKVETDQVATamhemaatvqdvarnAELASQAARQADEEARQGDAvvdQAVTRIERLA 457
Cdd:COG1196 240 ELEELEAELEELEAELEELEAELAELEAELEE---------------LRLELEELELELEEAQAEEY---ELLAELARLE 301

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 458 SEMDVSSEAMARLKNESEQIGSVLDVIKSVAEQTNLLALNAAIEAARAGDAGRGFAVVADEVRGLAQRTQQSTAEIEGLI 537
Cdd:COG1196 302 QDIARLEERRRELEERLEELEEELAELEEELEELEEELEELEEELEEAEEELEEAEAELAEAEEALLEAEAELAEAEEEL 381

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 538 QRLQQGAGEAAERLENSRSLTASTVELARRAGAALDSITRTVSDIQNMNLQIATAAEQQSTVAEEINRSVLSVRDVAEQS 617
Cdd:COG1196 382 EELAEELLEALRAAAELAAQLEELEEAEEALLERLERLEEELEELEEALAELEEEEEEEEEALEEAAEEEAELEEEEEAL 461

                       250       260
                ....*....|....*....|....*..
gi 81622028 618 AAASEQTAASSGELARLGTQLQAQVGR 644
Cdd:COG1196 462 LELLAELLEEAALLEAALAELLEELAE 488
NtrY COG5000
Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism ...
 307-397 3.11e-03

Signal transduction histidine kinase NtrY involved in nitrogen fixation and metabolism regulation [Signal transduction mechanisms];


Pssm-ID: 444024 [Multi-domain]  Cd Length: 422  Bit Score: 40.33  E-value: 3.11e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 81622028 307 VAGWAINRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDELGQLQRVMQRMGDSLRELvgrisdgVSQLASSAEEL 386
Cdd:COG5000  24 WLALLLARRLTRPLRRLAEATRAVAAGDLSVR----LPVTGDDEIGELARAFNRMTDQLKEQ-------REELEERRRYL 92

                        90
                ....*....|.
gi 81622028 387 SAVTEQTRAGV 397
Cdd:COG5000  93 ETILENLPAGV 103
HAMP pfam00672
HAMP domain;
312-367 7.28e-03

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 34.91  E-value: 7.28e-03
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*.
gi 81622028   312 INRQIVRPLDEALAQAEAIAAGDLGKRpqnpLTLQRRDELGQLQRVMQRMGDSLRE 367
Cdd:pfam00672   2 LARRILRPLRRLAEAARRIASGDLDVR----LPVSGRDEIGELARAFNQMAERLRE 53
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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