|
Name |
Accession |
Description |
Interval |
E-value |
| Glyco_transf_8 |
pfam01501 |
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to ... |
77-335 |
3.48e-60 |
|
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase.
Pssm-ID: 279798 [Multi-domain] Cd Length: 252 Bit Score: 194.85 E-value: 3.48e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 77 HIAMTLDSEYLRGSMAAVHSVLKHASCPeNVFFHFIAAEFDPASPRVLSQLVRSTFPSLSFkVYIFREDTVINLISSSIR 156
Cdd:pfam01501 1 CIALALDKNYLLGASVSIKSLLKNNSDF-ALNFHIFTDDIPVENLDILNWLASSYKPVLPL-LESDIKIFEYFSKLKLRS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 157 QALENPLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSKLIGAPEychanfTKYFTDGFWSDPLLSRVF 236
Cdd:pfam01501 79 PKYWSLLNYLRLYLPDLFPK-LDKILYLDADIVVQGDLSPLWDIDL-GGKVLAAVE------DNYFQRYPNFSEPIILEN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 237 SARNPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNvRGSCR 316
Cdd:pfam01501 151 FGPPACYFNAGMLLFDLDAWRKENITERYIKWLNLNENRTLWKLGDQDPLNIVFYGKVKPLDPRWNVLGLGYYN-KKKSL 229
|
250
....*....|....*....
gi 802787796 317 SLHPGPVSLLHWSGKGKPW 335
Cdd:pfam01501 230 NEITENAAVIHYNGPTKPW 248
|
|
| RfaJ |
COG1442 |
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ... |
76-372 |
1.11e-34 |
|
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441051 [Multi-domain] Cd Length: 301 Bit Score: 129.71 E-value: 1.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDSEYLRGSMAAVHSVLKHASCpENVFFHFIAAEFDPASPRVLSQLVRSTFPSLSFkvYIFREDTVINL-ISSS 154
Cdd:COG1442 6 INIVFAIDDNYLPGLGVSIASLLENNPD-RPYDFHILTDGLSDENKERLEALAAKYNVSIEF--IDVDDELLKDLpVSKH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 155 IRQAlenplNYARNYLGDILDNCVDRVIYLDSDIVVVDDIHKLWNTTLVGSKLIGAPEYCHANFTKYFTDgfwsdpLLSR 234
Cdd:COG1442 83 ISKA-----TYYRLLIPELLPDDYDKVLYLDADTLVLGDLSELWDIDLGGNLLAAVRDGTVTGSQKKRAK------RLGL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 235 VFSARnpcYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYelgslpP---FL-LVFAGNVEGIDHRWN-QHGLGGD 309
Cdd:COG1442 152 PDDDG---YFNSGVLLINLKKWREENITEKALEFLKENPDKLKY------PdqdILnIVLGGKVKFLPPRYNyQYSLYYE 222
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 802787796 310 NVRGSCRSLHPG----PVsLLHWSGKGKPWvrlDAKKPCPLDHLWQPYDLYKGYENIKMKDLNLGYL 372
Cdd:COG1442 223 LKDKSNKKELLEarknPV-IIHYTGPTKPW---HKWCTHPYADLYWEYLKKTPWKDIPLKKALRYKQ 285
|
|
| GT8_like_1 |
cd06429 |
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of ... |
76-338 |
2.91e-32 |
|
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.
Pssm-ID: 133051 [Multi-domain] Cd Length: 257 Bit Score: 122.11 E-value: 2.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDsEYLRGSMAAVHSVlKHASCPENVFFHFI---------AAEFDpasprvLSQLVRSTFPSLSFKVYIFREDT 146
Cdd:cd06429 1 IHVVIFSD-NRLAAAVVINSSI-SNNKDPSNLVFHIVtdnqnygamRSWFD------LNPLKIATVKVLNFDDFKLLGKV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 147 VINLISSSIRQALEN-----------PLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSKLIGApeych 215
Cdd:cd06429 73 KVDSLMQLESEADTSnlkqrkpeyisLLNFARFYLPELFPK-LEKVIYLDDDVVVQKDLTELWNTDL-GGGVAGA----- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 216 anftkyFTDGfwsdpllsrvfsarnpcyFNTGVMVMDLVKWREGNYRRRIENWMELQRKR--RIYELGSLPPFLLVFAGN 293
Cdd:cd06429 146 ------VETS------------------WNPGVNVVNLTEWRRQNVTETYEKWMELNQEEevTLWKLITLPPGLIVFYGL 201
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 802787796 294 VEGIDHRWNQHGLGGDnvrGSCRSLHPGPVSLLHWSGKGKPWVRL 338
Cdd:cd06429 202 TSPLDPSWHVRGLGYN---YGIRPQDIKAAAVLHFNGNMKPWLRT 243
|
|
| PLN02829 |
PLN02829 |
Probable galacturonosyltransferase |
72-369 |
1.38e-25 |
|
Probable galacturonosyltransferase
Pssm-ID: 215443 [Multi-domain] Cd Length: 639 Bit Score: 108.40 E-value: 1.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAmtLDSEYLRGSMAAVHSVLKHASCPENVFFHFIAAEFDPASPR----------------------------- 122
Cdd:PLN02829 328 DPQLYHYA--LFSDNVLAAAVVVNSTVTNAKHPSKHVFHIVTDRLNYAAMRmwflvnppgkatiqvqnieeftwlnssys 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 123 -VLSQLvrstfPSLSFKVYIFREdtviNLISSSIRQALENP-----LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHK 196
Cdd:PLN02829 406 pVLKQL-----GSQSMIDYYFRA----HRANSDSNLKYRNPkylsiLNHLRFYLPEIFPK-LNKVLFLDDDIVVQKDLTG 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 197 LWNTTLVGsKLIGAPEYCHANFTKYFTDGFWSDPLLSRVFSARnPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRR 276
Cdd:PLN02829 476 LWSIDLKG-NVNGAVETCGESFHRFDRYLNFSNPLISKNFDPH-ACGWAYGMNVFDLDEWKRQNITEVYHSWQKLNHDRQ 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 277 IYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGdNVRGSCRSLHPGPVslLHWSGKGKPWVRLDAKKpcpLDHLWQPydlY 356
Cdd:PLN02829 554 LWKLGTLPPGLITFWKRTYPLDRSWHVLGLGY-NPNVNQRDIERAAV--IHYNGNMKPWLEIGIPK---YRNYWSK---Y 624
|
330
....*....|...
gi 802787796 357 KGYENIKMKDLNL 369
Cdd:PLN02829 625 VDYDQVYLRECNI 637
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| Glyco_transf_8 |
pfam01501 |
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to ... |
77-335 |
3.48e-60 |
|
Glycosyl transferase family 8; This family includes enzymes that transfer sugar residues to donor molecules. Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. This family includes Lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, and glycogenin glucosyltransferase.
Pssm-ID: 279798 [Multi-domain] Cd Length: 252 Bit Score: 194.85 E-value: 3.48e-60
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 77 HIAMTLDSEYLRGSMAAVHSVLKHASCPeNVFFHFIAAEFDPASPRVLSQLVRSTFPSLSFkVYIFREDTVINLISSSIR 156
Cdd:pfam01501 1 CIALALDKNYLLGASVSIKSLLKNNSDF-ALNFHIFTDDIPVENLDILNWLASSYKPVLPL-LESDIKIFEYFSKLKLRS 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 157 QALENPLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSKLIGAPEychanfTKYFTDGFWSDPLLSRVF 236
Cdd:pfam01501 79 PKYWSLLNYLRLYLPDLFPK-LDKILYLDADIVVQGDLSPLWDIDL-GGKVLAAVE------DNYFQRYPNFSEPIILEN 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 237 SARNPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNvRGSCR 316
Cdd:pfam01501 151 FGPPACYFNAGMLLFDLDAWRKENITERYIKWLNLNENRTLWKLGDQDPLNIVFYGKVKPLDPRWNVLGLGYYN-KKKSL 229
|
250
....*....|....*....
gi 802787796 317 SLHPGPVSLLHWSGKGKPW 335
Cdd:pfam01501 230 NEITENAAVIHYNGPTKPW 248
|
|
| RfaJ |
COG1442 |
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope ... |
76-372 |
1.11e-34 |
|
Lipopolysaccharide biosynthesis protein, LPS:glycosyltransferase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 441051 [Multi-domain] Cd Length: 301 Bit Score: 129.71 E-value: 1.11e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDSEYLRGSMAAVHSVLKHASCpENVFFHFIAAEFDPASPRVLSQLVRSTFPSLSFkvYIFREDTVINL-ISSS 154
Cdd:COG1442 6 INIVFAIDDNYLPGLGVSIASLLENNPD-RPYDFHILTDGLSDENKERLEALAAKYNVSIEF--IDVDDELLKDLpVSKH 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 155 IRQAlenplNYARNYLGDILDNCVDRVIYLDSDIVVVDDIHKLWNTTLVGSKLIGAPEYCHANFTKYFTDgfwsdpLLSR 234
Cdd:COG1442 83 ISKA-----TYYRLLIPELLPDDYDKVLYLDADTLVLGDLSELWDIDLGGNLLAAVRDGTVTGSQKKRAK------RLGL 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 235 VFSARnpcYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYelgslpP---FL-LVFAGNVEGIDHRWN-QHGLGGD 309
Cdd:COG1442 152 PDDDG---YFNSGVLLINLKKWREENITEKALEFLKENPDKLKY------PdqdILnIVLGGKVKFLPPRYNyQYSLYYE 222
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 802787796 310 NVRGSCRSLHPG----PVsLLHWSGKGKPWvrlDAKKPCPLDHLWQPYDLYKGYENIKMKDLNLGYL 372
Cdd:COG1442 223 LKDKSNKKELLEarknPV-IIHYTGPTKPW---HKWCTHPYADLYWEYLKKTPWKDIPLKKALRYKQ 285
|
|
| GT8_like_1 |
cd06429 |
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of ... |
76-338 |
2.91e-32 |
|
GT8_like_1 represents a subfamily of GT8 with unknown function; A subfamily of glycosyltransferase family 8 with unknown function: Glycosyltransferase family 8 comprises enzymes with a number of known activities; lipopolysaccharide galactosyltransferase lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase and inositol 1-alpha-galactosyltransferase. It is classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed.
Pssm-ID: 133051 [Multi-domain] Cd Length: 257 Bit Score: 122.11 E-value: 2.91e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDsEYLRGSMAAVHSVlKHASCPENVFFHFI---------AAEFDpasprvLSQLVRSTFPSLSFKVYIFREDT 146
Cdd:cd06429 1 IHVVIFSD-NRLAAAVVINSSI-SNNKDPSNLVFHIVtdnqnygamRSWFD------LNPLKIATVKVLNFDDFKLLGKV 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 147 VINLISSSIRQALEN-----------PLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSKLIGApeych 215
Cdd:cd06429 73 KVDSLMQLESEADTSnlkqrkpeyisLLNFARFYLPELFPK-LEKVIYLDDDVVVQKDLTELWNTDL-GGGVAGA----- 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 216 anftkyFTDGfwsdpllsrvfsarnpcyFNTGVMVMDLVKWREGNYRRRIENWMELQRKR--RIYELGSLPPFLLVFAGN 293
Cdd:cd06429 146 ------VETS------------------WNPGVNVVNLTEWRRQNVTETYEKWMELNQEEevTLWKLITLPPGLIVFYGL 201
|
250 260 270 280
....*....|....*....|....*....|....*....|....*
gi 802787796 294 VEGIDHRWNQHGLGGDnvrGSCRSLHPGPVSLLHWSGKGKPWVRL 338
Cdd:cd06429 202 TSPLDPSWHVRGLGYN---YGIRPQDIKAAAVLHFNGNMKPWLRT 243
|
|
| GT8_A4GalT_like |
cd04194 |
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the ... |
76-335 |
1.14e-28 |
|
A4GalT_like proteins catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface; The members of this family of glycosyltransferases catalyze the addition of galactose or glucose residues to the lipooligosaccharide (LOS) or lipopolysaccharide (LPS) of the bacterial cell surface. The enzymes exhibit broad substrate specificities. The known functions found in this family include: Alpha-1,4-galactosyltransferase, LOS-alpha-1,3-D-galactosyltransferase, UDP-glucose:(galactosyl) LPS alpha1,2-glucosyltransferase, UDP-galactose: (glucosyl) LPS alpha1,2-galactosyltransferase, and UDP-glucose:(glucosyl) LPS alpha1,2-glucosyltransferase. Alpha-1,4-galactosyltransferase from N. meningitidis adds an alpha-galactose from UDP-Gal (the donor) to a terminal lactose (the acceptor) of the LOS structure of outer membrane. LOSs are virulence factors that enable the organism to evade the immune system of host cells. In E. coli, the three alpha-1,2-glycosyltransferases, that are involved in the synthesis of the outer core region of the LPS, are all members of this family. The three enzymes share 40 % of sequence identity, but have different sugar donor or acceptor specificities, representing the structural diversity of LPS.
Pssm-ID: 133037 [Multi-domain] Cd Length: 248 Bit Score: 111.92 E-value: 1.14e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDSEYLRGSMAAVHSVLKHAScPENVFFHFIAAEFDPASPRVLSQLVRSTFPSLSF-KVYIFRED---TVINLI 151
Cdd:cd04194 1 MNIVFAIDDNYAPYLAVTIKSILANNS-KRDYDFYILNDDISEENKKKLKELLKKYNSSIEFiKIDNDDFKffpATTDHI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 152 SSSIrqalenplnYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSKLIGA-PEYCHANFTKYFTDGFWSDP 230
Cdd:cd04194 80 SYAT---------YYRLLIPDLLPD-YDKVLYLDADIIVLGDLSELFDIDL-GDNLLAAvRDPFIEQEKKRKRRLGGYDD 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 231 LLsrvfsarnpcYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIY-ELGSLPpflLVFAGNVEGIDHRWN-QHGLGG 308
Cdd:cd04194 149 GS----------YFNSGVLLINLKKWREENITEKLLELIKEYGGRLIYpDQDILN---AVLKDKILYLPPRYNfQTGFYY 215
|
250 260 270
....*....|....*....|....*....|.
gi 802787796 309 --DNVRGSCRSLHPG--PVSLLHWSGKGKPW 335
Cdd:cd04194 216 llKKKSKEEQELEEArkNPVIIHYTGSDKPW 246
|
|
| PLN02829 |
PLN02829 |
Probable galacturonosyltransferase |
72-369 |
1.38e-25 |
|
Probable galacturonosyltransferase
Pssm-ID: 215443 [Multi-domain] Cd Length: 639 Bit Score: 108.40 E-value: 1.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAmtLDSEYLRGSMAAVHSVLKHASCPENVFFHFIAAEFDPASPR----------------------------- 122
Cdd:PLN02829 328 DPQLYHYA--LFSDNVLAAAVVVNSTVTNAKHPSKHVFHIVTDRLNYAAMRmwflvnppgkatiqvqnieeftwlnssys 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 123 -VLSQLvrstfPSLSFKVYIFREdtviNLISSSIRQALENP-----LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHK 196
Cdd:PLN02829 406 pVLKQL-----GSQSMIDYYFRA----HRANSDSNLKYRNPkylsiLNHLRFYLPEIFPK-LNKVLFLDDDIVVQKDLTG 475
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 197 LWNTTLVGsKLIGAPEYCHANFTKYFTDGFWSDPLLSRVFSARnPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRR 276
Cdd:PLN02829 476 LWSIDLKG-NVNGAVETCGESFHRFDRYLNFSNPLISKNFDPH-ACGWAYGMNVFDLDEWKRQNITEVYHSWQKLNHDRQ 553
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 277 IYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGdNVRGSCRSLHPGPVslLHWSGKGKPWVRLDAKKpcpLDHLWQPydlY 356
Cdd:PLN02829 554 LWKLGTLPPGLITFWKRTYPLDRSWHVLGLGY-NPNVNQRDIERAAV--IHYNGNMKPWLEIGIPK---YRNYWSK---Y 624
|
330
....*....|...
gi 802787796 357 KGYENIKMKDLNL 369
Cdd:PLN02829 625 VDYDQVYLRECNI 637
|
|
| Glyco_transf_8 |
cd00505 |
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis ... |
83-337 |
4.15e-25 |
|
Members of glycosyltransferase family 8 (GT-8) are involved in lipopolysaccharide biosynthesis and glycogen synthesis; Members of this family are involved in lipopolysaccharide biosynthesis and glycogen synthesis. GT-8 comprises enzymes with a number of known activities: lipopolysaccharide galactosyltransferase, lipopolysaccharide glucosyltransferase 1, glycogenin glucosyltransferase, and N-acetylglucosaminyltransferase. GT-8 enzymes contains a conserved DXD motif which is essential in the coordination of a catalytic divalent cation, most commonly Mn2+.
Pssm-ID: 132996 [Multi-domain] Cd Length: 246 Bit Score: 102.52 E-value: 4.15e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 83 DSEYLRGSMAAVHSVLKHAscPENVFFHFIAAEfdpasprvLSQLVRSTFPSLSFK---VYIFREDTVINLISSSIRQAL 159
Cdd:cd00505 9 GDEYLRGAIVLMKSVLRHR--TKPLRFHVLTNP--------LSDTFKAALDNLRKLynfNYELIPVDILDSVDSEHLKRP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 160 ENPLNYARNYLGDILDNCvDRVIYLDSDIVVVDDIHKLWNTTLVGSKLIGAPEYCHANFTKYFtdGFWSDPllsrvfsAR 239
Cdd:cd00505 79 IKIVTLTKLHLPNLVPDY-DKILYVDADILVLTDIDELWDTPLGGQELAAAPDPGDRREGKYY--RQKRSH-------LA 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 240 NPCYFNTGVMVMDLVKWREG-NYRRRIENWMELQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDnvRGS-CRS 317
Cdd:cd00505 149 GPDYFNSGVFVVNLSKERRNqLLKVALEKWLQSLSSLSGGDQDLLNTFFKQVPFIVKSLPCIWNVRLTGCY--RSLnCFK 226
|
250 260
....*....|....*....|
gi 802787796 318 LHPGPVSLLHWSGKGKPWVR 337
Cdd:cd00505 227 AFVKNAKVIHFNGPTKPWNK 246
|
|
| PLN02742 |
PLN02742 |
Probable galacturonosyltransferase |
159-353 |
8.17e-25 |
|
Probable galacturonosyltransferase
Pssm-ID: 215395 [Multi-domain] Cd Length: 534 Bit Score: 106.01 E-value: 8.17e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 159 LENP-----LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLVGSkLIGAPEYCHANFTKYFTDGFWSDPLLS 233
Cdd:PLN02742 330 FRNPkylsmLNHLRFYIPEIYPA-LEKVVFLDDDVVVQKDLTPLFSIDLHGN-VNGAVETCLETFHRYHKYLNFSHPLIS 407
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 234 RVFSArNPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGD-NVr 312
Cdd:PLN02742 408 SHFDP-DACGWAFGMNVFDLVAWRKANVTAIYHYWQEQNVDRTLWKLGTLPPGLLTFYGLTEPLDRRWHVLGLGYDtNI- 485
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 802787796 313 gSCRSLHPGPVslLHWSGKGKPWVRLDAKKPCPldhLWQPY 353
Cdd:PLN02742 486 -DPRLIESAAV--LHFNGNMKPWLKLAIERYKP---LWERY 520
|
|
| PLN02910 |
PLN02910 |
polygalacturonate 4-alpha-galacturonosyltransferase |
72-356 |
6.86e-24 |
|
polygalacturonate 4-alpha-galacturonosyltransferase
Pssm-ID: 215493 [Multi-domain] Cd Length: 657 Bit Score: 103.49 E-value: 6.86e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAMTLDSeyLRGSMAAVHSVLKHASCPENVFFHFIAAEFDPASPR----------------------------- 122
Cdd:PLN02910 342 DPSLYHYAIFSDN--VLATSVVVNSTVLHAKEPQKHVFHIVTDKLNFAAMKmwfiinppakatiqveniddfkwlnssyc 419
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 123 -VLSQLvrstfPSLSFKVYIFREDTVINLISSSIRQALENP-----LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHK 196
Cdd:PLN02910 420 sVLRQL-----ESARIKEYYFKANHPSSLSAGADNLKYRNPkylsmLNHLRFYLPEVYPK-LEKILFLDDDIVVQKDLTP 493
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 197 LWNTTLVGsKLIGAPEYCHANFTKYFTDGFWSDPLLSRVFSArNPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRR 276
Cdd:PLN02910 494 LWSIDMQG-MVNGAVETCKESFHRFDKYLNFSNPKISENFDP-NACGWAFGMNMFDLKEWRKRNITGIYHYWQDLNEDRT 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 277 IYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNvrgscrSLHPGPV---SLLHWSGKGKPWVRLDAKKPCPldhLWQPY 353
Cdd:PLN02910 572 LWKLGSLPPGLITFYNLTYPLDRSWHVLGLGYDP------ALNQTEIenaAVVHYNGNYKPWLDLAIAKYKP---YWSRY 642
|
...
gi 802787796 354 DLY 356
Cdd:PLN02910 643 VQY 645
|
|
| PLN02870 |
PLN02870 |
Probable galacturonosyltransferase |
163-361 |
1.20e-23 |
|
Probable galacturonosyltransferase
Pssm-ID: 215468 [Multi-domain] Cd Length: 533 Bit Score: 102.32 E-value: 1.20e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 163 LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLVGsKLIGAPEYCHAN----FTKYFTDGF-WSDPLLSRVFS 237
Cdd:PLN02870 329 LNHLRIYLPELFPN-LDKVVFLDDDVVIQRDLSPLWDIDLGG-KVNGAVETCRGEdewvMSKRFRNYFnFSHPLIAKNLD 406
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 238 ArNPCYFNTGVMVMDLVKWREGNYRRRIENWME--LQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNvRGSC 315
Cdd:PLN02870 407 P-EECAWAYGMNIFDLRAWRKTNIRETYHSWLKenLKSNLTMWKLGTLPPALIAFKGHVHPIDPSWHMLGLGYQS-KTNI 484
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 802787796 316 RSLHPGPVslLHWSGKGKPWVRLDakkpcpLDHLWQPYDLYKGYEN 361
Cdd:PLN02870 485 ESVKKAAV--IHYNGQSKPWLEIG------FEHLRPFWTKYVNYSN 522
|
|
| PLN02659 |
PLN02659 |
Probable galacturonosyltransferase |
163-353 |
5.94e-22 |
|
Probable galacturonosyltransferase
Pssm-ID: 215356 [Multi-domain] Cd Length: 534 Bit Score: 97.41 E-value: 5.94e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 163 LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLVGsKLIGAPEYCHAN--------FTKYFTdgfWSDPLLSR 234
Cdd:PLN02659 330 MNHIRIHLPELFPS-LNKVVFLDDDIVVQTDLSPLWDIDMNG-KVNGAVETCRGEdkfvmskkLKSYLN---FSHPLIAK 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 235 VFSArNPCYFNTGVMVMDLVKWREGNYRRRIENWME--LQRKRRIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNVR 312
Cdd:PLN02659 405 NFDP-NECAWAYGMNIFDLEAWRKTNISSTYHHWLEenLKSDLSLWQLGTLPPGLIAFHGHVHVIDPFWHMLGLGYQENT 483
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 802787796 313 GSCRSLHPGpvsLLHWSGKGKPWvrLDAKKPcPLDHLWQPY 353
Cdd:PLN02659 484 SLADAESAG---VVHFNGRAKPW--LDIAFP-QLRPLWAKY 518
|
|
| PLN02718 |
PLN02718 |
Probable galacturonosyltransferase |
72-362 |
1.44e-20 |
|
Probable galacturonosyltransferase
Pssm-ID: 178320 [Multi-domain] Cd Length: 603 Bit Score: 93.42 E-value: 1.44e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAMTLDSeyLRGSMAAVHSVLKHASCPENVFFHFIAAEFD-PASPR--VLSQLVRSTFPSLS---FKVYIFRED 145
Cdd:PLN02718 310 DPDLYHYVVFSDN--VLACSVVVNSTISSSKEPEKIVFHVVTDSLNyPAISMwfLLNPPGKATIQILNiddMNVLPADYN 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 146 -TVINLISSSIRqaLENPLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLVGsKLIGAPEYCHANFTKYFT- 223
Cdd:PLN02718 388 sLLMKQNSHDPR--YISALNHARFYLPDIFPG-LNKIVLFDHDVVVQRDLSRLWSLDMKG-KVVGAVETCLEGEPSFRSm 463
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 224 DGF--WSDPLLSRVFSARnPCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYELGSLPPFLLVFAGNVEGIDHRW 301
Cdd:PLN02718 464 DTFinFSDPWVAKKFDPK-ACTWAFGMNLFDLEEWRRQKLTSVYHKYLQLGVKRPLWKAGSLPIGWLTFYNQTVALDKRW 542
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 802787796 302 NQHGLGGDNvrgSCRSLHPGPVSLLHWSGKGKPWVRLDAKKpcpldhlwqpydlYKGYENI 362
Cdd:PLN02718 543 HVLGLGHES---GVGASDIEQAAVIHYDGVMKPWLDIGIGK-------------YKRYWNI 587
|
|
| PLN02867 |
PLN02867 |
Probable galacturonosyltransferase |
163-338 |
4.17e-20 |
|
Probable galacturonosyltransferase
Pssm-ID: 178458 [Multi-domain] Cd Length: 535 Bit Score: 91.89 E-value: 4.17e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 163 LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLVGsKLIGA--PEYCHAN------FTKYFTdgfWSDPLLSR 234
Cdd:PLN02867 331 LNHLRIYIPELFPD-LNKIVFLDDDVVVQHDLSSLWELDLNG-KVVGAvvDSWCGDNccpgrkYKDYLN---FSHPLISS 405
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 235 VFSARNpCYFNTGVMVMDLVKWREGNYRRRIENWMELQRKR--RIYELGSLPPFLLVFAGNVEGIDHRWNQHGLGGDNVR 312
Cdd:PLN02867 406 NLDQER-CAWLYGMNVFDLKAWRRTNITEAYHKWLKLSLNSglQLWQPGALPPALLAFKGHVHPIDPSWHVAGLGSRPPE 484
|
170 180
....*....|....*....|....*.
gi 802787796 313 GSCRSLhpGPVSLLHWSGKGKPWVRL 338
Cdd:PLN02867 485 VPREIL--ESAAVLHFSGPAKPWLEI 508
|
|
| PLN02523 |
PLN02523 |
galacturonosyltransferase |
72-353 |
4.54e-20 |
|
galacturonosyltransferase
Pssm-ID: 215286 [Multi-domain] Cd Length: 559 Bit Score: 91.86 E-value: 4.54e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAMTLDSeyLRGSMAAVHSVLKHASCPENVFFHFIAAEFDPASPRVLSQL------------------------ 127
Cdd:PLN02523 245 DPSLYHYAIFSDN--VIAASVVVNSAVKNAKEPWKHVFHVVTDRMNLAAMKVMFKMrdlngahvevkavedykflnssyv 322
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 128 -VRSTFPSLSFKVYIFrEDTVINLISSSIRQALENP-----LNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTT 201
Cdd:PLN02523 323 pVLRQLESANLQKFYF-ENKLENATKDSSNMKFRNPkylsmLNHLRFYLPEMYPK-LHRILFLDDDVVVQKDLTGLWKID 400
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 202 LVGsKLIGAPEYCHANFTKYFTDGFWSDPLLSRVFsarNP--CYFNTGVMVMDLVKWREGNYRRRIENWMELQRKRRIYE 279
Cdd:PLN02523 401 MDG-KVNGAVETCFGSFHRYAQYLNFSHPLIKEKF---NPkaCAWAYGMNIFDLDAWRREKCTEQYHYWQNLNENRTLWK 476
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 802787796 280 LGSLPPFLLVFAGNVEGIDHRWNQHGLgGDNVRGSCRSLHPGPVslLHWSGKGKPWvrLDAKKPcPLDHLWQPY 353
Cdd:PLN02523 477 LGTLPPGLITFYSTTKPLDKSWHVLGL-GYNPSISMDEIRNAAV--IHFNGNMKPW--LDIAMN-QFKPLWTKY 544
|
|
| PLN02769 |
PLN02769 |
Probable galacturonosyltransferase |
72-338 |
4.15e-16 |
|
Probable galacturonosyltransferase
Pssm-ID: 215412 [Multi-domain] Cd Length: 629 Bit Score: 79.74 E-value: 4.15e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 72 DPSLVHIAMtLDSEYLRGSMAaVHSVLKHASCPENVFFH--------------FIAAEFDPASPRVLS----QL------ 127
Cdd:PLN02769 327 DPSLRHYVI-FSKNVLAASVV-INSTVVHSRESGNIVFHvltdaqnyyamkhwFDRNSYKEAAVQVLNiedlILkdldkf 404
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 128 -VRSTFPSLSFKVYIfreDTVINLISSSIRQALENPLNYARNYLGDILDNcVDRVIYLDSDIVVVDDIHKLWNTTLvGSK 206
Cdd:PLN02769 405 aLKQLSLPEEFRVSF---RSVDNPSSKQMRTEYLSVFSHSHFLLPEIFKK-LKKVVVLDDDVVVQRDLSFLWNLDM-GGK 479
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 207 LIGAPEYCHANFTKYftdgfwsDPLLSRVFSARNPCYFNTGVMVMDLVKWREGNYrrrIENWMELQRKRRIYELGS---- 282
Cdd:PLN02769 480 VNGAVQFCGVRLGQL-------KNYLGDTNFDTNSCAWMSGLNVIDLDKWRELDV---TETYLKLLQKFSKDGEESlraa 549
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 283 -LPPFLLVFAGNVEGIDHRWNQHGLGGD---NVRGSCRSlhpgpvSLLHWSGKGKPWVRL 338
Cdd:PLN02769 550 aLPASLLTFQDLIYPLDDRWVLSGLGHDygiDEQAIKKA------AVLHYNGNMKPWLEL 603
|
|
| GT8_LARGE_C |
cd06431 |
LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in ... |
76-273 |
5.08e-06 |
|
LARGE catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis; The catalytic domain of LARGE is a putative glycosyltransferase. Mutations of LARGE in mouse and human cause dystroglycanopathies, a disease associated with hypoglycosylation of the membrane protein alpha-dystroglycan (alpha-DG) and consequent loss of extracellular ligand binding. LARGE needs to both physically interact with alpha-dystroglycan and function as a glycosyltransferase in order to stimulate alpha-dystroglycan hyperglycosylation. LARGE localizes to the Golgi apparatus and contains three conserved DxD motifs. While two of the motifs are indispensible for glycosylation function, one is important for localization of th eenzyme. LARGE was originally named because it covers approximately large trunck of genomic DNA, more than 600bp long. The predicted protein structure contains an N-terminal cytoplasmic domain, a transmembrane region, a coiled-coil motif, and two putative catalytic domains. This catalytic domain has closest homology to GT8 glycosyltransferase involved in lipooligosaccharide synthesis.
Pssm-ID: 133053 Cd Length: 280 Bit Score: 47.47 E-value: 5.08e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 76 VHIAMTLDS-EYLRGSMAAVHSVLKHASCPenVFFHFIAaefDPASPRVLSQLVRS-TFPSLSFKVYIFRE-DTVINLIS 152
Cdd:cd06431 1 IHVAIVCAGyNASRDVVTLVKSVLFYRRNP--LHFHLIT---DEIARRILATLFQTwMVPAVEVSFYNAEElKSRVSWIP 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 153 SSirqalenplNYARNY------LGDILDNCVDRVIYLDSDIVVVDDIHKLWNT--TLVGSKLIGAPEychaNFTKYFTD 224
Cdd:cd06431 76 NK---------HYSGIYglmklvLTEALPSDLEKVIVLDTDITFATDIAELWKIfhKFTGQQVLGLVE----NQSDWYLG 142
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 802787796 225 GFWSD----PLLSRvfsarnpcYFNTGVMVMDLVKWREgnyrrriENWMELQR 273
Cdd:cd06431 143 NLWKNhrpwPALGR--------GFNTGVILLDLDKLRK-------MKWESMWR 180
|
|
| PRK15171 |
PRK15171 |
lipopolysaccharide 3-alpha-galactosyltransferase; |
71-357 |
1.49e-04 |
|
lipopolysaccharide 3-alpha-galactosyltransferase;
Pssm-ID: 185093 [Multi-domain] Cd Length: 334 Bit Score: 43.20 E-value: 1.49e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 71 CDPSLVHIAMTLDSEYLRGSMAAVHSVLKHAscPENVF-FHFIAAEFDPASPRVLSQLvrstfpSLSFKVYIfredtVIN 149
Cdd:PRK15171 21 ASKNSLDIAYGIDKNFLFGCGVSIASVLLNN--PDKSLvFHVFTDYISDADKQRFSAL------AKQYNTRI-----NIY 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 150 LISSSIRQALENPLN-----YARNYLGDILDNCVDRVIYLDSDIVVVDDIHKLWNTTLVGSKlIGApeychanftkYFTD 224
Cdd:PRK15171 88 LINCERLKSLPSTKNwtyatYFRFIIADYFIDKTDKVLYLDADIACKGSIKELIDLDFAENE-IAA----------VVAE 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 225 G---FWSDPLLSRVFSARNPCYFNTGVMVMDLVKWREGNYRRR-IENWMELQRKRRIYELGSlPPFLLVFAGNVEGIDHR 300
Cdd:PRK15171 157 GdaeWWSKRAQSLQTPGLASGYFNSGFLLINIPAWAQENISAKaIEMLADPEIVSRITHLDQ-DVLNILLAGKVKFIDAK 235
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 802787796 301 WN-QHGLG---GDNVrgscrslhPGPVS----LLHWSGKGKPWVR----------LDAKKPCPldhlWQPYDLYK 357
Cdd:PRK15171 236 YNtQFSLNyelKDSV--------INPVNdetvFIHYIGPTKPWHSwadypvsqyfLKAKEASP----WKNEALLK 298
|
|
| GT8_HUGT1_C_like |
cd06432 |
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain ... |
178-258 |
8.02e-04 |
|
The C-terminal domain of HUGT1-like is highly homologous to the GT 8 family; C-terminal domain of glycoprotein glucosyltransferase (UGT). UGT is a large glycoprotein whose C-terminus contains the catalytic activity. This catalytic C-terminal domain is highly homologous to Glycosyltransferase Family 8 (GT 8) and contains the DXD motif that coordinates donor sugar binding, characteristic for Family 8 glycosyltransferases. GT 8 proteins are retaining enzymes based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. The non-catalytic N-terminal portion of the human UTG1 (HUGT1) has been shown to monitor the protein folding status and activate its glucosyltransferase activity.
Pssm-ID: 133054 Cd Length: 248 Bit Score: 40.84 E-value: 8.02e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 802787796 178 VDRVIYLDSDIVVVDDIHKLWNTTLVGSKLIGAPeYCH-----ANFtKYFTDGFWSDPLLSRVfsarnpcYFNTGVMVMD 252
Cdd:cd06432 96 VDKVIFVDADQIVRTDLKELMDMDLKGAPYGYTP-FCDsrkemDGF-RFWKQGYWKSHLRGRP-------YHISALYVVD 166
|
....*.
gi 802787796 253 LVKWRE 258
Cdd:cd06432 167 LKRFRR 172
|
|
| GT8_Glycogenin |
cd02537 |
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; Glycogenin ... |
179-250 |
1.47e-03 |
|
Glycogenin belongs the GT 8 family and initiates the biosynthesis of glycogen; Glycogenin initiates the biosynthesis of glycogen by incorporating glucose residues through a self-glucosylation reaction at a Tyr residue, and then acts as substrate for chain elongation by glycogen synthase and branching enzyme. It contains a conserved DxD motif and an N-terminal beta-alpha-beta Rossmann-like fold that are common to the nucleotide-binding domains of most glycosyltransferases. The DxD motif is essential for coordination of the catalytic divalent cation, most commonly Mn2+. Glycogenin can be classified as a retaining glycosyltransferase, based on the relative anomeric stereochemistry of the substrate and product in the reaction catalyzed. It is placed in glycosyltransferase family 8 which includes lipopolysaccharide glucose and galactose transferases and galactinol synthases.
Pssm-ID: 133018 [Multi-domain] Cd Length: 240 Bit Score: 39.94 E-value: 1.47e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 802787796 179 DRVIYLDSDIVVVDDIHKLWNttlvgskligAPEYCHANFtkyftDGFWsdpllsrvfsarnPCYFNTGVMV 250
Cdd:cd02537 91 DKVVFLDADTLVLRNIDELFD----------LPGEFAAAP-----DCGW-------------PDLFNSGVFV 134
|
|
| |
