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Conserved domains on  [gi|785766404|gb|AJZ94921|]
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chemotaxis sensory transducer [Pseudomonas simiae]

Protein Classification

methyl-accepting chemotaxis protein( domain architecture ID 11435591)

methyl-accepting chemotaxis protein (MCP) is a bacterial receptor that mediates chemotaxis to diverse signals, responding to changes in the concentration of attractants and repellents in the environment by altering swimming behavior

CATH:  1.10.287.950
Gene Ontology:  GO:0006935
PubMed:  18165013|20738376
SCOP:  4003862

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
9-541 2.31e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


:

Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 266.50  E-value: 2.31e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   9 GLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASWMPSIENIHDSAAIVASIRLEALRLATTDESRIRDNSKALI 88
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  89 TRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLTDMIT 168
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 169 FNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQL 248
Cdd:COG0840  161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 249 LTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQA 328
Cdd:COG0840  241 ADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 329 SDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAV 408
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 409 VADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAE 488
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|...
gi 785766404 489 QQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFVL 541
Cdd:COG0840  481 EQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
9-541 2.31e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 266.50  E-value: 2.31e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   9 GLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASWMPSIENIHDSAAIVASIRLEALRLATTDESRIRDNSKALI 88
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  89 TRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLTDMIT 168
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 169 FNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQL 248
Cdd:COG0840  161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 249 LTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQA 328
Cdd:COG0840  241 ADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 329 SDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAV 408
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 409 VADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAE 488
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|...
gi 785766404 489 QQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFVL 541
Cdd:COG0840  481 EQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 281-539 9.10e-60

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 198.66  E-value: 9.10e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   281 SSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNK 360
Cdd:smart00283   3 SEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   361 AESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQG 440
Cdd:smart00283  83 VEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNE 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   441 TVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSA 520
Cdd:smart00283 163 AVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISA 242

                          250
                   ....*....|....*....
gi 785766404   521 ASQELSRLAVDLNGLVARF 539
Cdd:smart00283 243 AAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 306-505 2.21e-45

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 158.17  E-value: 2.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 306 TEMSAAVDEVAGNAVSSAEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQT 385
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 386 NLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSA 465
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 785766404 466 LEKITAAISQISQRNLVIASAAEQQALVARDVDRSLVNIR 505
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
161-539 2.08e-37

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 145.48  E-value: 2.08e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 161 KSLTDMITFNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVS 240
Cdd:PRK15041 165 KQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKPIEVD 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 241 GKDEPAQLLTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAv 320
Cdd:PRK15041 245 GSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENA- 323

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 321 ssaeaSQASdedskHGHYQISETIRSIQNLVDEVLgasNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAG 400
Cdd:PRK15041 324 -----RQAS-----HLALSASETAQRGGKVVDNVV---QTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAG 390

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 401 EAGRGFAVVADEVRSLAQRTQDSTEEIEQMItgiqQGTQGTVEalnssaeqAGHTLqrANSAGSALEKITAAISQISQRN 480
Cdd:PRK15041 391 EQGRGFAVVAGEVRNLAQRSAQAAREIKSLI----EDSVGKVD--------VGSTL--VESAGETMAEIVSAVTRVTDIM 456

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 785766404 481 LVIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARF 539
Cdd:PRK15041 457 GEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVF 515
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 341-508 6.08e-31

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 118.30  E-value: 6.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  341 SETIRSIQNLVDEVLGASNKaesLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRT 420
Cdd:pfam00015   8 SEEAQDGGKEVANVVGQMEQ---IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  421 QDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAEQQALVARDVDRS 500
Cdd:pfam00015  85 AQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQA 164


                  ....*...
gi 785766404  501 LVNIRDLS 508
Cdd:pfam00015 165 VARMDQVT 172
 
Name Accession Description Interval E-value
Tar COG0840
Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];
9-541 2.31e-82

Methyl-accepting chemotaxis protein (MCP) [Signal transduction mechanisms];


Pssm-ID: 440602 [Multi-domain]  Cd Length: 533  Bit Score: 266.50  E-value: 2.31e-82
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   9 GLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASWMPSIENIHDSAAIVASIRLEALRLATTDESRIRDNSKALI 88
Cdd:COG0840    1 LLILLLLLALLLALLLLALSLLALLAAALLILLALLLAALTALALLLLLSLLALLLLLLLLALALLLVLLALLLLLALVV 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  89 TRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLTDMIT 168
Cdd:COG0840   81 LLALLLALLLLLLALLALALAALALLAALAALLALLELLLAALLAALAIALLALAALLALAALALALLALALLAAAAAAA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 169 FNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQL 248
Cdd:COG0840  161 AALAALLEAAALALAAAALALALLAAALLALVALAIILALLLSRSITRPLRELLEVLERIAEGDLTVRIDVDSKDEIGQL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 249 LTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQA 328
Cdd:COG0840  241 ADAFNRMIENLRELVGQVRESAEQVASASEELAASAEELAAGAEEQAASLEETAAAMEELSATVQEVAENAQQAAELAEE 320

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 329 SDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAV 408
Cdd:COG0840  321 ASELAEEGGEVVEEAVEGIEEIRESVEETAETIEELGESSQEIGEIVDVIDDIAEQTNLLALNAAIEAARAGEAGRGFAV 400

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 409 VADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAE 488
Cdd:COG0840  401 VADEVRKLAERSAEATKEIEELIEEIQSETEEAVEAMEEGSEEVEEGVELVEEAGEALEEIVEAVEEVSDLIQEIAAASE 480

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|...
gi 785766404 489 QQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFVL 541
Cdd:COG0840  481 EQSAGTEEVNQAIEQIAAAAQENAASVEEVAAAAEELAELAEELQELVSRFKL 533
MA smart00283
Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo ...
 281-539 9.10e-60

Methyl-accepting chemotaxis-like domains (chemotaxis sensory transducer); Thought to undergo reversible methylation in response to attractants or repellants during bacterial chemotaxis.


Pssm-ID: 214599 [Multi-domain]  Cd Length: 262  Bit Score: 198.66  E-value: 9.10e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   281 SSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNK 360
Cdd:smart00283   3 SEAVEEIAAGAEEQAEELEELAERMEELSASIEEVAANADEIAATAQSAAEAAEEGREAVEDAITAMDQIREVVEEAVSA 82

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   361 AESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQG 440
Cdd:smart00283  83 VEELEESSDEIGEIVSVIDDIADQTNLLALNAAIEAARAGEAGRGFAVVADEVRKLAERSAESAKEIESLIKEIQEETNE 162

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   441 TVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSA 520
Cdd:smart00283 163 AVAAMEESSSEVEEGVELVEETGDALEEIVDSVEEIADLVQEIAAATDEQAAGSEEVNAAIDEIAQVTQETAAMSEEISA 242

                          250
                   ....*....|....*....
gi 785766404   521 ASQELSRLAVDLNGLVARF 539
Cdd:smart00283 243 AAEELSGLAEELDELVERF 261
MCP_signal cd11386
Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis ...
 306-505 2.21e-45

Methyl-accepting chemotaxis protein (MCP), signaling domain; Methyl-accepting chemotaxis proteins (MCPs or chemotaxis receptors) are an integral part of the transmembrane protein complex that controls bacterial chemotaxis, together with the histidine kinase CheA, the receptor-coupling protein CheW, receptor-modification enzymes, and localized phosphatases. MCPs contain a four helix trans membrane region, an N-terminal periplasmic ligand binding domain, and a C-terminal HAMP domain followed by a cytoplasmic signaling domain. This C-terminal signaling domain dimerizes into a four-helix bundle and interacts with CheA through the adaptor protein CheW.


Pssm-ID: 206779 [Multi-domain]  Cd Length: 200  Bit Score: 158.17  E-value: 2.21e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 306 TEMSAAVDEVAGNAVSSAEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQT 385
Cdd:cd11386    1 EELSASIEEVAASADQVAETSQQAAELAEKGREAAEDAINQMNQIDESVDEAVSAVEELEESSAEIGEIVEVIDDIAEQT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 386 NLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSA 465
Cdd:cd11386   81 NLLALNAAIEAARAGEAGRGFAVVADEVRKLAEESAEAAKEIEELIEEIQEQTEEAVEAMEETSEEVEEGVELVEETGRA 160

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|
gi 785766404 466 LEKITAAISQISQRNLVIASAAEQQALVARDVDRSLVNIR 505
Cdd:cd11386  161 FEEIVASVEEVADGIQEISAATQEQSASTQEIAAAVEEIA 200
PRK15041 PRK15041
methyl-accepting chemotaxis protein;
161-539 2.08e-37

methyl-accepting chemotaxis protein;


Pssm-ID: 185001 [Multi-domain]  Cd Length: 554  Bit Score: 145.48  E-value: 2.08e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 161 KSLTDMITFNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVS 240
Cdd:PRK15041 165 KQYVAYMEQNDRLYDIAVSDNNASYSQAMWILVGVMIVVLAVIFAVWFGIKASLVAPMNRLIDSIRHIAGGDLVKPIEVD 244

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 241 GKDEPAQLLTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAv 320
Cdd:PRK15041 245 GSNEMGQLAESLRHMQGELMRTVGDVRNGANAIYSGASEIATGNNDLSSRTEQQAASLEETAASMEQLTATVKQNAENA- 323

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 321 ssaeaSQASdedskHGHYQISETIRSIQNLVDEVLgasNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAG 400
Cdd:PRK15041 324 -----RQAS-----HLALSASETAQRGGKVVDNVV---QTMRDISTSSQKIADIISVIDGIAFQTNILALNAAVEAARAG 390

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 401 EAGRGFAVVADEVRSLAQRTQDSTEEIEQMItgiqQGTQGTVEalnssaeqAGHTLqrANSAGSALEKITAAISQISQRN 480
Cdd:PRK15041 391 EQGRGFAVVAGEVRNLAQRSAQAAREIKSLI----EDSVGKVD--------VGSTL--VESAGETMAEIVSAVTRVTDIM 456

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 785766404 481 LVIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARF 539
Cdd:PRK15041 457 GEIASASDEQSRGIDQVGLAVAEMDRVTQQNAALVEESAAAAAALEEQASRLTEAVAVF 515
PRK09793 PRK09793
methyl-accepting chemotaxis protein IV;
174-541 7.19e-35

methyl-accepting chemotaxis protein IV;


Pssm-ID: 182079 [Multi-domain]  Cd Length: 533  Bit Score: 137.90  E-value: 7.19e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 174 VQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLdqALIVAR--TIASGDLSQPIAVSGKDEPAQLLTA 251
Cdd:PRK09793 174 LEAASAQSQRNYQISALVFISMIIVAAIYISSALWWTRKMIVQPL--AIIGSHfdSIAAGNLARPIAVYGRNEITAIFAS 251

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 252 LATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQASDE 331
Cdd:PRK09793 252 LKTMQQALRGTVSDVRKGSQEMHIGIAEIVAGNNDLSSRTEQQAASLAQTAASMEQLTATVGQNADNARQASELAKNAAT 331

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 332 DSKHGHYQISETIRSIQNLvdevlgasnkaeslAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVAD 411
Cdd:PRK09793 332 TAQAGGVQVSTMTHTMQEI--------------ATSSQKIGDIISVIDGIAFQTNILALNAAVEAARAGEQGRGFAVVAG 397

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 412 EVRSLAQRTQDSTEE----IEQMITGIQQGTqgtvealnssaeqaghtlQRANSAGSALEKITAAISQISQRNLVIASAA 487
Cdd:PRK09793 398 EVRNLASRSAQAAKEikglIEESVNRVQQGS------------------KLVNNAAATMTDIVSSVTRVNDIMGEIASAS 459

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|....
gi 785766404 488 EQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFVL 541
Cdd:PRK09793 460 EEQRRGIEQVAQAVSQMDQVTQQNASLVEEAAVATEQLANQADHLSSRVAVFTL 513
PRK15048 PRK15048
methyl-accepting chemotaxis protein II; Provisional
 159-541 8.80e-34

methyl-accepting chemotaxis protein II; Provisional


Pssm-ID: 185008 [Multi-domain]  Cd Length: 553  Bit Score: 134.75  E-value: 8.80e-34
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 159 LNKSLTDMITFNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIA 238
Cdd:PRK15048 161 MGEAFAQYALSSEKLYRDIVTDNADDYRFAQWQLAVIALVVVLILLVAWYGIRRMLLTPLAKIIAHIREIAGGNLANTLT 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 239 VSGKDEPAQLLTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGN 318
Cdd:PRK15048 241 IDGRSEMGDLAQSVSHMQRSLTDTVTHVREGSDAIYAGTREIAAGNTDLSSRTEQQASALEETAASMEQLTATVKQNADN 320

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 319 AVSSAEASQASDEDSKHGHYQISETIRSIQNLVDevlgasnkaeslavQAQDISKVLEVIRGIAGQTNLLALNAAIEAAR 398
Cdd:PRK15048 321 ARQASQLAQSASDTAQHGGKVVDGVVKTMHEIAD--------------SSKKIADIISVIDGIAFQTNILALNAAVEAAR 386

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 399 AGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMItgiqqgtQGTVEALNSsaeqaGHTLqrANSAGSALEKITAAISQISQ 478
Cdd:PRK15048 387 AGEQGRGFAVVAGEVRNLASRSAQAAKEIKALI-------EDSVSRVDT-----GSVL--VESAGETMNNIVNAVTRVTD 452

                        330       340       350       360       370       380
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 785766404 479 RNLVIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFVL 541
Cdd:PRK15048 453 IMGEIASASDEQSRGIDQVALAVSEMDRVTQQNASLVQESAAAAAALEEQASRLTQAVSAFRL 515
MCPsignal pfam00015
Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to ...
 341-508 6.08e-31

Methyl-accepting chemotaxis protein (MCP) signalling domain; This domain is thought to transduce the signal to CheA since it is highly conserved in very diverse MCPs.


Pssm-ID: 333767 [Multi-domain]  Cd Length: 172  Bit Score: 118.30  E-value: 6.08e-31
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  341 SETIRSIQNLVDEVLGASNKaesLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRT 420
Cdd:pfam00015   8 SEEAQDGGKEVANVVGQMEQ---IAQSSKKISDIISVIDEIAFQTNLLALNAAIEAARAGEQGRGFAVVADEVRKLAERS 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  421 QDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAEQQALVARDVDRS 500
Cdd:pfam00015  85 AQAAKEIEALIIEIQKQTNDSTASIESTRQRVEVGSTIVESTGEALKEIVDAVAEIADIVQEIAAASDEQSAGIDQVNQA 164


                  ....*...
gi 785766404  501 LVNIRDLS 508
Cdd:pfam00015 165 VARMDQVT 172
4HB_MCP_1 pfam12729
Four helix bundle sensory module for signal transduction; This family is a four helix bundle ...
 5-185 1.94e-17

Four helix bundle sensory module for signal transduction; This family is a four helix bundle that operates as a ubiquitous sensory module in prokaryotic signal-transduction. The 4HB_MCP is always found between two predicted transmembrane helices indicating that it detects only extracellular signals. In many cases the domain is associated with a cytoplasmic HAMP domain suggesting that most proteins carrying the bundle might share the mechanism of transmembrane signalling which is well-characterized in E coli chemoreceptors. This domain recognizes citrate and TCA cycle intermediates, cis-aconitate, boric acid, Phenanthrene, pyrene and benzopyrene (Matilla et el., FEMS Microbiology Reviews, fuab043, 45, 2021, 1. https://doi.org/10.1093/femsre/fuab043).


Pssm-ID: 432749 [Multi-domain]  Cd Length: 181  Bit Score: 80.37  E-value: 1.94e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404    5 NMRIGLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASWMPSIENIHDSAAIVASIRLEALRLATTDESRIRDNS 84
Cdd:pfam12729   1 NLKIRTKLILLFLLLALLLIIVGVVGLYSLKQINDNLDTMYEDRLLPIKWLGDIRANLLELRANLLELILTTDPAERDEL 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   85 KALITRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLT 164
Cdd:pfam12729  81 LKDIEELRAEIDKLLEKYEKTILTDEEKKLFAEFKENLNAYRAVRNKVLELAKAGNKDEAYQLYKTEGRPAREAMIEALE 160

                         170       180
                  ....*....|....*....|.
gi 785766404  165 DMITFNQSGVQTAVDSAAQTY 185
Cdd:pfam12729 161 ELVDYNLKVAKEAYKDNKASY 181
HAMP COG2770
HAMP domain [Signal transduction mechanisms];
2-540 1.49e-06

HAMP domain [Signal transduction mechanisms];


Pssm-ID: 442051 [Multi-domain]  Cd Length: 631  Bit Score: 50.88  E-value: 1.49e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   2 SLRNMRIGLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASWMPSIENIHDSAAIVASIRLEALRLATTDESRIR 81
Cdd:COG2770   24 ALLVLALISLRLLLALLLLLLLLLALLLLLLLLLLLLLAALVLLALLLAAALLLLLLLLSLVALAALLLALLLLLLLALL 103

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  82 DNSKALITRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNK 161
Cdd:COG2770  104 LLLAALLLLLLLAALALLLLLLLLLAALLALLLALALLALLLGLAAARLLLAALLALAAALALALGAGELLLLADLAAAI 183

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 162 SLTDMITFNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSG 241
Cdd:COG2770  184 AALLAALLLLLLGGLLLVVLLEAALAALLLLLLLALLALLLALLLALLLARRITRPLRRLAEAARRIAAGDLDVRIPVSR 263

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 242 KDEPAQLLTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVS 321
Cdd:COG2770  264 KDEIGELARAFNRMADSLRESIEEAEEEEELAEAELARLLEALLELLLALLLLLLALLLLAAAALLLELLLLLLLALLLL 343

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 322 SAEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGE 401
Cdd:COG2770  344 LLLAADLLLALALAALLLLLALELLLEAELLVLLALEALALEAELAAVLALLAALAAALLLLELALEELVLALLALALLA 423

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 402 AGRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNL 481
Cdd:COG2770  424 LAAAAAAAEAAAAALELAAAAIAAAAAAEAEGGLAELEAEELVAAAEALLLLAALLLLAALGALELLLLEEEEEAGAAAE 503

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 785766404 482 VIASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLVARFV 540
Cdd:COG2770  504 ELAEELLLLEGLLLLLLLEAEALEVAEELLELEEAALLLAAAAELAALLALLLALAAVE 562
HAMP smart00304
HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;
212-264 3.62e-06

HAMP (Histidine kinases, Adenylyl cyclases, Methyl binding proteins, Phosphatases) domain;


Pssm-ID: 197640 [Multi-domain]  Cd Length: 53  Bit Score: 44.16  E-value: 3.62e-06
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|...
gi 785766404   212 RSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQLLTALATMQAQLQGTLR 264
Cdd:smart00304   1 RRLLRPLRRLAEAAQRIADGDLTVRLPVDGRDEIGELARAFNEMADRLEETIA 53
HAMP pfam00672
HAMP domain;
212-260 5.72e-06

HAMP domain;


Pssm-ID: 459898 [Multi-domain]  Cd Length: 53  Bit Score: 43.77  E-value: 5.72e-06
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....*....
gi 785766404  212 RSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQLLTALATMQAQLQ 260
Cdd:pfam00672   4 RRILRPLRRLAEAARRIASGDLDVRLPVSGRDEIGELARAFNQMAERLR 52
HAMP cd06225
Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; ...
 215-259 8.34e-06

Histidine kinase, Adenylyl cyclase, Methyl-accepting protein, and Phosphatase (HAMP) domain; HAMP is a signaling domain which occurs in a wide variety of signaling proteins, many of which are bacterial. The HAMP domain consists of two alpha helices connected by an extended linker. The structure of the Af1503 HAMP dimer from Archaeoglobus fulgidus has been solved using nuclear magnetic resonance, revealing a parallel four-helix bundle; this structure has been confirmed by cross-linking analysis of HAMP domains from the Escherichia coli aerotaxis receptor Aer. It has been suggested that the four-helix arrangement can rotate between the unusually packed conformation observed in the NMR structure and a canonical coiled-coil arrangement. Such rotation may coincide with signal transduction, but a common mechanism by which HAMP domains relay a variety of input signals has yet to be established.


Pssm-ID: 381743 [Multi-domain]  Cd Length: 45  Bit Score: 42.82  E-value: 8.34e-06
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 785766404 215 TAPLDQALIVARTIASGDLSQPIAVSGKDEPAQLLTALATMQAQL 259
Cdd:cd06225    1 TRPLRRLTEAARRIAEGDLDVRVPVRSKDEIGELARAFNQMAERL 45
MCP2201-like_sensor cd19411
ligand-binding sensor domain of Comamonas testosteroni CNB-2 MCP2201 and similar ...
 48-181 1.01e-05

ligand-binding sensor domain of Comamonas testosteroni CNB-2 MCP2201 and similar chemoreceptors; This family includes the ligand-binding sensor domain of Comamonas testosteroni transmembrane chemoreceptor CNB-2 MCP2201 and similar chemoreceptors. The C. testosteroni methyl-accepting chemotaxis protein MCP2201 triggers chemotaxis towards tricarboxylic acid cycle intermediates such as citric acid and aromatic compounds. While the apo-form ligand binding domain (LBD) forms a typical four-helix bundle homodimer, similar to other chemoreceptors in the superfamily such as Escherichia coli Tar and Tsr, the citrate-bound LBD reveals a four-helix bundle homotrimer. This type of oligomerization has never been observed in other bacterial chemoreceptor LBD. Site-directed mutations of key amino acid residues have demonstrated the physiological importance of the homotrimer for chemotaxis.


Pssm-ID: 438629 [Multi-domain]  Cd Length: 138  Bit Score: 45.32  E-value: 1.01e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  48 WMPSIENIHDSAAIVASIRLEALRLATTDESRIRDNSKALITRQHTELQTLLDHHKTLLSGDEEREMLTQLEGNANAYLS 127
Cdd:cd19411    5 RYPKVRLANEWKDNVNANARRTRNLLLSTDPAERAKELARIAAARARITELLKKLEKLITSPEGKALLAAIAEARAAYLA 84

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 785766404 128 LVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLTDMITFNQSGVQTAVDSA 181
Cdd:cd19411   85 ARDKVLELKKAGDREEARALLLGELRPAQAAYLAALDALVDYQEELMDAAAAEA 138
CHASE3 COG5278
Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];
3-536 3.68e-04

Extracytoplasmic sensor domain CHASE3 (specificity unknown) [Signal transduction mechanisms];


Pssm-ID: 444089 [Multi-domain]  Cd Length: 530  Bit Score: 43.36  E-value: 3.68e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404   3 LRNMRIGLRASLSFGVLASLLVIVGMFGLGQMAKLRQSALVIEASwMPSIENIHDSAAIVASIRLEALRLATTDESRIRD 82
Cdd:COG5278    1 MKNLSIRRKLLLGFALALLLLLVLGVLSYLSLNRLREASEWVEHT-YEVLRALEELLSALLDAETGQRGYLLTGDESFLE 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404  83 NSKALITRQHTELQTLldhHKTLLSGDEEREMLTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKS 162
Cdd:COG5278   80 PYEEARAEIDELLAEL---RSLTADNPEQQARLDELEALIDQWLAELEQVIALRRAGGLEAALALVRSGEGKALMDEIRA 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 163 LTDMITFNQSGVQTAVDSAAQTYSSAQWIVGSIIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSGK 242
Cdd:COG5278  157 RLLLLALALAALLLAAAALLLLLLALAALLALAELLLLALARALAALLLLLLLEAELAAAAALLAAAAALAALAALELLA 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 243 DEPAQLLTALATMQAQLQGTLRGISESAQQLGCAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSS 322
Cdd:COG5278  237 ALALALALLLAALLLALLAALALAALLAAALLALAALLLALAAAAALAAAAALELAAAEALALAELELELLLAAAAAAAA 316

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 323 AEASQASDEDSKHGHYQISETIRSIQNLVDEVLGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEA 402
Cdd:COG5278  317 AAAAAAAALAALLALALATALAAAAAALALLAALLAEAAAAAAEEAEAAAEAAAAALAGLAEVEAEGAAEAVELEVLAIA 396

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 403 GRGFAVVADEVRSLAQRTQDSTEEIEQMITGIQQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLV 482
Cdd:COG5278  397 AAAAAAAAEAAAAAAAAAAASAAEALELAEALAEALALAEEEALALAAASSELAEAGAALALAAAEALAEELAAVAALAA 476

                        490       500       510       520       530
                 ....*....|....*....|....*....|....*....|....*....|....
gi 785766404 483 IASAAEQQALVARDVDRSLVNIRDLSTQTAAGATQTSAASQELSRLAVDLNGLV 536
Cdd:COG5278  477 LAAAAAALAEAEAAAALAAAAALSLALALAALLLAAAEAALAAALAAALASAEL 530
PRK10600 PRK10600
nitrate/nitrite two-component system sensor histidine kinase NarX;
212-296 1.77e-03

nitrate/nitrite two-component system sensor histidine kinase NarX;


Pssm-ID: 182581 [Multi-domain]  Cd Length: 569  Bit Score: 41.19  E-value: 1.77e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 212 RSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQLLTALATMQAQLQgtlrgisesaqqlgcaaeEMSSVMEQ----S 287
Cdd:PRK10600 147 RRLLQPWRQLLSMANAVSHRDFTQRANISGRDEMAMLGTALNNMSAELA------------------ESYAVLEQrvqeK 208


                 ....*....
gi 785766404 288 TRDLQAQND 296
Cdd:PRK10600 209 TAGLEQKNQ 217
NarQ COG3850
Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction ...
 115-520 3.71e-03

Signal transduction histidine kinase NarQ, nitrate/nitrite-specific [Signal transduction mechanisms];


Pssm-ID: 443059 [Multi-domain]  Cd Length: 448  Bit Score: 39.87  E-value: 3.71e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 115 LTQLEGNANAYLSLVRQIVALVDKDQQQDAIDLLNSRLAPQGVILNKSLTDMITFNQSGVQTAVDSAAQTYSSAQWIVGS 194
Cdd:COG3850   43 LRLLSLLASAGLLAALLAALLLLLSLGLLALLLALLLLLLLLLLAALLSLLLLLLLLLLLLLLLLLLLLAAAINRKLALL 122

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 195 IIVLALTATLLLAWLLTRSITAPLDQALIVARTIASGDLSQPIAVSGKDEPAQLLTALATMQAQLQGTLRGISESAQQLG 274
Cdd:COG3850  123 RLLLALLLALLLAYLLRRRIVRPLRRLTQAAERIARGDFDARVPVSGRDELGTLARAFNRMADELQELYAELEEEEELEA 202

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 275 CAAEEMSSVMEQSTRDLQAQNDEIEQAATAVTEMSAAVDEVAGNAVSSAEASQASDEDSKHGHYQISETIRSIQNLVDEV 354
Cdd:COG3850  203 ELELLALLDELLLLAALLLLLALLLALLLAALLAALLLLLLLQDALAESELLALNILAGLLELLLALLLLLLASALLLLE 282

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 355 LGASNKAESLAVQAQDISKVLEVIRGIAGQTNLLALNAAIEAARAGEAGRGFAVVADEVRSLAQRTQDSTEEIEQMITGI 434
Cdd:COG3850  283 LELLALLLELVELLALAAAEEALLLLVELAALLLLLLLQAIANASLLLIALASVVAALLELASILALQAALEAAAAGAAL 362

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 785766404 435 QQGTQGTVEALNSSAEQAGHTLQRANSAGSALEKITAAISQISQRNLVIASAAEQQALVARDVDRSLVNIRDLSTQTAAG 514
Cdd:COG3850  363 AAAAAAAGLARALAQAGADAAEALGLLAEASEGAAGQGAGLVDVEGGVAGEGGLVVLIVSIIAGGEAIARGEALAARGLA 442


                 ....*.
gi 785766404 515 ATQTSA 520
Cdd:COG3850  443 AAAALA 448
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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