|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
36-853 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1479.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 36 GERIQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSA 115
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 116 IYDTLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFP 195
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 196 NLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLI 275
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELME----IIPGPDFPTGGIILGRSGIREAYRTGRGSI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 276 TMRAVVNTEEIKGRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDETSgRTGQRLVLVLKRDAVPKVVLNNLY 355
Cdd:PRK05560 238 VMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQ 435
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 436 GREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYGD 515
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 516 ERRTKILPYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFTN 595
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 596 KGRVYRLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAVR 675
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 676 LmtDENgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVWGDsDKDLL 755
Cdd:PRK05560 637 L--DEG----DELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVRED-SQEIL 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 756 VVTDEGFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLA 835
Cdd:PRK05560 708 TVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLI 787
|
810
....*....|....*...
gi 781870637 836 KPDKNDEIISIALNAEKD 853
Cdd:PRK05560 788 RLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
36-847 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1380.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 36 GERIQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSA 115
Cdd:COG0188 7 AERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDSA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 116 IYDTLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFP 195
Cdd:COG0188 87 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 196 NLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLdnliRIIKGPDFPTGATILGHKGIEQAYRTGRGLI 275
Cdd:COG0188 167 NLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELM----EYIPGPDFPTGGIIVGREGIREAYETGRGSI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 276 TMRAVVNTEEIK-GRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNL 354
Cdd:COG0188 243 RVRAKAEIEELKrGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDE-SDRDGMRIVIELKRDANPEVVLNQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 355 YKHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSS 434
Cdd:COG0188 322 YKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRAS 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 435 QGREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYG 514
Cdd:COG0188 402 KDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYG 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 515 DERRTKILPYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFT 594
Cdd:COG0188 482 DERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 595 NKGRVYRLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAV 674
Cdd:COG0188 562 NKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 675 RLmtDENgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVwgDSDKDL 754
Cdd:COG0188 642 NL--KEG----DELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVV--DEEDDL 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 755 LVVTDEGFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTL 834
Cdd:COG0188 712 LTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRL 791
|
810
....*....|...
gi 781870637 835 AKPDKNDEIISIA 847
Cdd:COG0188 792 IRLDEGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
43-851 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1169.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 43 DLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVR 122
Cdd:TIGR01063 5 NIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDTLVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 123 MAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGS 202
Cdd:TIGR01063 85 MAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 203 SGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVN 282
Cdd:TIGR01063 165 SGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLE----VIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 283 TEEI-KGRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQLQ 361
Cdd:TIGR01063 241 IEEDsKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 362 QTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQGREDAR 441
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 442 PKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYGDERRTKI 521
Cdd:TIGR01063 400 TRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 522 L-PYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFTNKGRVY 600
Cdd:TIGR01063 480 VyDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVY 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 601 RLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAVRLmtDE 680
Cdd:TIGR01063 560 WLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL--DD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 681 NgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVWGDSdkDLLVVTDE 760
Cdd:TIGR01063 638 G----DELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEES--YLLIVTEN 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 761 GFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLAKPDKN 840
Cdd:TIGR01063 710 GYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDED 789
|
810
....*....|.
gi 781870637 841 DEIISIALNAE 851
Cdd:TIGR01063 790 DKLVSVSKVAK 800
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
61-509 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 671.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 61 VDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVRMAQSWSMRYMLVDGQGNF 140
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 141 GSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPHNMRE 220
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 221 VAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVNTEEIKGRMCLVVTELPYQ 300
Cdd:cd00187 161 VIDALRALIDNPEASIDELME----IIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 301 VNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQLQQTFGANMLALV-DGVPRTL 379
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 380 SLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSqgrEDARPKLME---FLDIDQVQAD 456
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEeleKLGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 781870637 457 AILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEI 509
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
42-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 631.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 42 RDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLV 121
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 122 RMAQSWSMRYMLVDGQGNFGSPGD-DPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCN 200
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRLDgDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 201 GSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGieqayrtgrglITMRAV 280
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMM----IPWGPDFPTGGEIVGPGK-----------YVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 281 VNTEEIKGrmcLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDETSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQL 360
Cdd:smart00434 226 IEIEDDNT---IVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 361 QQTFGANMLALVD-GVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAE-ERDHILQGLLKALDAIEEVIKLIRSSQ-GR 437
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 781870637 438 EDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQR 499
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
63-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 613.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 63 RALPDVRDGMKPVHRRVVYAMYDGgYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVRMAQSWSMRYMLVDGQGNFGS 142
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 143 -PGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPHNMREV 221
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 222 AEGVHWALDHPEASReelldnLIRIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVNTEEikgRMCLVVTELPYQV 301
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 302 NPDRLVASIREAVRDGKIQGIADMRDETSgrTGQRLVLVLKRDAVPKVVLNNLYKHSQLQQTFGANMLALVDGVPRTLSL 381
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 382 DAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQGREDARPKLMEflDIDQVQADAILSM 461
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 781870637 462 QLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELD 507
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| PRK05560 |
PRK05560 |
DNA gyrase subunit A; Validated |
36-853 |
0e+00 |
|
DNA gyrase subunit A; Validated
Pssm-ID: 235502 [Multi-domain] Cd Length: 805 Bit Score: 1479.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 36 GERIQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSA 115
Cdd:PRK05560 2 GDRIIPVNIEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMNELGNTPDKPYKKSARIVGDVMGKYHPHGDSA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 116 IYDTLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFP 195
Cdd:PRK05560 82 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARMSKIAHELLADIDKETVDFVPNYDGSEQEPTVLPARFP 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 196 NLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLI 275
Cdd:PRK05560 162 NLLVNGSSGIAVGMATNIPPHNLGEVIDACLALIDNPDITIEELME----IIPGPDFPTGGIILGRSGIREAYRTGRGSI 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 276 TMRAVVNTEEIKGRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDETSgRTGQRLVLVLKRDAVPKVVLNNLY 355
Cdd:PRK05560 238 VMRAKAEIEEIKGREAIIVTEIPYQVNKARLIEKIAELVKEKKIEGISDLRDESD-RDGMRIVIELKRDAVPEVVLNNLY 316
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQ 435
Cdd:PRK05560 317 KHTQLQTSFGINMLALVDGQPKLLNLKEILEAFLEHRKEVITRRTRFELRKAEERAHILEGLLIALDNIDEVIALIRASP 396
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 436 GREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYGD 515
Cdd:PRK05560 397 TPAEAKEGLMERFGLSEIQAQAILDMRLQRLTGLERDKIEDEYKELLALIADLKDILASPERLLEIIKEELLEIKEKFGD 476
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 516 ERRTKILPYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFTN 595
Cdd:PRK05560 477 PRRTEIIEGEGDIDDEDLIPEEDVVVTLTHGGYIKRTPLDEYRAQRRGGKGVSGAKTKEDDFVEHLFVASTHDTLLFFTN 556
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 596 KGRVYRLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAVR 675
Cdd:PRK05560 557 RGRVYRLKVYEIPEASRTARGRPIVNLLPLEPGEKITAILPVREFDDDKYLFFATKNGTVKKTSLSEFSNIRSNGIIAIN 636
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 676 LmtDENgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVWGDsDKDLL 755
Cdd:PRK05560 637 L--DEG----DELIGVRLTDGDDDILLATKNGKAIRFPESD--VRPMGRTARGVRGIKLREGDEVVSMDVVRED-SQEIL 707
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 756 VVTDEGFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLA 835
Cdd:PRK05560 708 TVTENGYGKRTPVSEYRLQGRGGKGVITIKITEKNGKLVGALPVDDDDEIMLITDSGKLIRTRVSEISITGRNTQGVRLI 787
|
810
....*....|....*...
gi 781870637 836 KPDKNDEIISIALNAEKD 853
Cdd:PRK05560 788 RLDEGDKVVSVARVAEEE 805
|
|
| GyrA |
COG0188 |
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair]; |
36-847 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A [Replication, recombination and repair];
Pssm-ID: 439958 [Multi-domain] Cd Length: 804 Bit Score: 1380.52 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 36 GERIQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSA 115
Cdd:COG0188 7 AERIIPVNLEDEMKRSYLDYAMSVIVGRALPDVRDGLKPVHRRILYAMHELGLTPDKPYKKSARVVGDVMGKYHPHGDSA 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 116 IYDTLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFP 195
Cdd:COG0188 87 VYDALVRMAQDFSMRYPLVDGQGNFGSIDGDPAAAMRYTEARLAKIAEELLADIDKDTVDFVPNYDGSEQEPTVLPARFP 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 196 NLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLdnliRIIKGPDFPTGATILGHKGIEQAYRTGRGLI 275
Cdd:COG0188 167 NLLVNGSSGIAVGMATNIPPHNLGEVIDACIALIDNPDATIEELM----EYIPGPDFPTGGIIVGREGIREAYETGRGSI 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 276 TMRAVVNTEEIK-GRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNL 354
Cdd:COG0188 243 RVRAKAEIEELKrGREQIVVTEIPYQVNKARLIEKIAELVKEKKIEGISDVRDE-SDRDGMRIVIELKRDANPEVVLNQL 321
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 355 YKHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSS 434
Cdd:COG0188 322 YKHTQLQTSFGINMLALVDGRPRVLNLKEILEAFLDHRREVVTRRTQFELRKAEERAHILEGLLIALDNIDEVIAIIRAS 401
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 435 QGREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYG 514
Cdd:COG0188 402 KDPDEAKEALMERFGLSEIQAEAILDMRLRRLTGLEREKIEDEYAELLKEIAELEDILASEERLLKIIKEELLEIKKKYG 481
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 515 DERRTKILPYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFT 594
Cdd:COG0188 482 DERRTEIEEAEGEIDIEDLIPDEDVVVTLSHKGYIKRTPLDTYRAQRRGGKGVSGMGTKEEDFVEHLFVASTHDTLLFFT 561
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 595 NKGRVYRLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAV 674
Cdd:COG0188 562 NKGRVYRLKVYELPEGSRTAKGKPIVNLLPLEPGEKITAVLPVKEFDEDKYLLFATKKGTVKKTPLSDFSNIRKNGIIAI 641
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 675 RLmtDENgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVwgDSDKDL 754
Cdd:COG0188 642 NL--KEG----DELVGVALTDGDDDVLLATSNGKAIRFPESD--VRPMGRTARGVRGIRLKEGDEVVGMAVV--DEEDDL 711
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 755 LVVTDEGFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTL 834
Cdd:COG0188 712 LTVTENGYGKRTPLSEYRLQGRGGKGVITIKLTEKNGKLVGALVVNDDDELMLITSSGQLIRTPVSDIRVTGRNTQGVRL 791
|
810
....*....|...
gi 781870637 835 AKPDKNDEIISIA 847
Cdd:COG0188 792 IRLDEGDKVVSVA 804
|
|
| gyrA |
TIGR01063 |
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). ... |
43-851 |
0e+00 |
|
DNA gyrase, A subunit; This model describes the common type II DNA topoisomerase (DNA gyrase). Two apparently independently arising families, one in the Proteobacteria and one in Gram-positive lineages, are both designated toposisomerase IV. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273423 [Multi-domain] Cd Length: 800 Bit Score: 1169.78 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 43 DLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVR 122
Cdd:TIGR01063 5 NIEEEMKRSYLDYAMSVIVSRALPDVRDGLKPVHRRILYAMYELGLTPDKPYKKSARIVGDVMGKYHPHGDSAIYDTLVR 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 123 MAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGS 202
Cdd:TIGR01063 85 MAQDFSLRYPLVDGQGNFGSIDGDPPAAMRYTEARLTKIAEELLRDIDKETVDFVPNYDGSEQEPTVLPSRFPNLLVNGS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 203 SGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVN 282
Cdd:TIGR01063 165 SGIAVGMATNIPPHNLGEIIDALLAYIDNPDISIQELLE----VIKGPDFPTGGIILGRSGIRSAYETGRGSIVIRARAE 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 283 TEEI-KGRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQLQ 361
Cdd:TIGR01063 241 IEEDsKGREAIIVTEIPYQVNKARLIEKIAELVREKKIEGISDIRDE-SDREGIRIVIELKRDAVAEVVLNNLYKQTQLQ 319
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 362 QTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQGREDAR 441
Cdd:TIGR01063 320 VSFGINMLALVKGLPKVLNLKELLEAFVEHRKDVITRRTIFELRKAEERAHILEGLLIALDNIDEVIALIRASQNTEEAK 399
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 442 PKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYGDERRTKI 521
Cdd:TIGR01063 400 TRLVERFSLSEIQAQAILDMRLQRLTGLEREKLQEEYKELLELIADLEDILASEERVLEIIREELEEIKEQFGDPRRTEI 479
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 522 L-PYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTSTHNWLLFFTNKGRVY 600
Cdd:TIGR01063 480 VyDESEDIDIEDLIARENVVVTLSHNGYVKRVPVSAYRLQKRGGKGVSGADMKDDDFIEQLLVASTHDYLLFFTNRGKVY 559
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 601 RLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSPRQGGLIAVRLmtDE 680
Cdd:TIGR01063 560 WLKVYQIPEASRTAKGKPIVNLLPLQPDERITAILSVKEFDDGLYLFFATKNGVVKKTSLTEFSNIRSNGIIAIKL--DD 637
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 681 NgenaDELIGAALCNADDDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVVWGDSdkDLLVVTDE 760
Cdd:TIGR01063 638 G----DELISVRLTSGEDEVMLGSKNGKAVRFPEED--VRPMGRAARGVRGIKLKNEDFVVSLLVVSEES--YLLIVTEN 709
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 761 GFAKRSAVSEYRLQGRNGYGVKALQLAEGRGSLVGALIVSEDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLAKPDKN 840
Cdd:TIGR01063 710 GYGKRTSIEEYRETSRGGKGVKSIKITDRNGQVVGAIAVDDDDELMLITSAGKLIRTSVQDVSEQGRNTQGVRLIRLDED 789
|
810
....*....|.
gi 781870637 841 DEIISIALNAE 851
Cdd:TIGR01063 790 DKLVSVSKVAK 800
|
|
| PRK05561 |
PRK05561 |
DNA topoisomerase 4 subunit A; |
33-768 |
0e+00 |
|
DNA topoisomerase 4 subunit A;
Pssm-ID: 235503 [Multi-domain] Cd Length: 742 Bit Score: 851.32 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 33 LMVGERIQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHG 112
Cdd:PRK05561 4 MSMLEGIEDLPLEEFLEERYLRYAMYVIMDRALPDVRDGLKPVQRRILYAMSELGLTPDAKFKKSARVVGDVLGKYHPHG 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 113 DSAIYDTLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPA 192
Cdd:PRK05561 84 DSSIYDAMVRMAQDFSYRYPLVDGQGNFGSIDGDPAAAMRYTEARLSPIAELLLEEIDEGTVDFVPNFDGTLKEPTVLPA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 193 RFPNLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLdnliRIIKGPDFPTGATIL-GHKGIEQAYRTG 271
Cdd:PRK05561 164 RFPNLLLNGATGIAVGMATDIPPHNLREVIDAAIHLIDNPDATLEELM----EFVPGPDFPTGGEIItGRDGIRKAYETG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 272 RGLITMRAVVNTEEIK-GRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQ-RLVLVLKRDAV-PK 348
Cdd:PRK05561 240 RGSIRVRARWEIEDLAgGRWQIVITELPYQVSKAKLIEQIAELMNAKKLPGIADVRDE-SDRENPvRIVIEPKSNRVdPE 318
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 349 VVLNNLYKHSQLQQTFGANMLAL-VDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEV 427
Cdd:PRK05561 319 ALMNHLFATTDLESSYRVNMNAIgLDGRPRVKGLKEILSEWLDHRREVVTRRSQFRLDKVEKRLHILEGLLIAFLNIDEV 398
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 428 IKLIRSSqgrEDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELD 507
Cdd:PRK05561 399 IRIIRES---DEPKANLMARFDLSEIQAEAILELRLRRLAKLEEIEIRKEQDELRKEIAELEAILASERKLRKLIKKELK 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 508 EIVAKYGDERRTKIL--PYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQhrggkgikGAKLREDDVVDHFFLTS 585
Cdd:PRK05561 476 ADAKKFGDPRRTPIEeaEEAIAIDEEALIPDEPVTVVLSKKGWVRRAKGHSIDAS--------GLSFKEGDSLLFAFEAR 547
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 586 THNWLLFFTNKGRVYRLKAYELPEGSRDskGQHVANLLQFGPDETIQTVLSipnYEVAKYLVLATRSGKVKKTALAEYDS 665
Cdd:PRK05561 548 TTDKLLLFTSTGRVYSLPVHELPSARGD--GEPLTGLVDLAPGEEIVHVLA---FDPDQKLLLASSAGYGFVVTLEDLVA 622
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 666 PRQGGLIAVRLmtdengENADELIGAALCNADDDIMLVSRKGMSLKFTAndEQLRPMGRqTAGVQGMKFRDGDELLAMDV 745
Cdd:PRK05561 623 RTRAGKAVINL------KDGDEVLPPVPVEDDDHLAAITSNGRLLVFPL--SELPELGK-GKGVKLINLPKDDDGLVDLR 693
|
730 740
....*....|....*....|...
gi 781870637 746 VWGDSDKDLLVVTDEGFAKRSAV 768
Cdd:PRK05561 694 VLNPEDGLVLLTAGKRKLKLKPS 716
|
|
| TOP4c |
cd00187 |
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), ... |
61-509 |
0e+00 |
|
DNA Topoisomerase, subtype IIA; domain A'; bacterial DNA topoisomerase IV (C subunit, ParC), bacterial DNA gyrases (A subunit, GyrA),mammalian DNA toposiomerases II. DNA topoisomerases are essential enzymes that regulate the conformational changes in DNA topology by catalysing the concerted breakage and rejoining of DNA strands during normal cellular growth.
Pssm-ID: 238111 [Multi-domain] Cd Length: 445 Bit Score: 671.97 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 61 VDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVRMAQSWSMRYMLVDGQGNF 140
Cdd:cd00187 1 NGRALPDVRDGLKPVQRRILYAMFKRGLTPDKPEKKVARLVGDVAGKYHPHGDSSLYDTIVRMAQDFSNNIPLLDPQGNF 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 141 GSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPHNMRE 220
Cdd:cd00187 81 GSRDGDDAAAMRYTETRLSPIARLLLPDIDDPTVDFVPNYDGQEVEPEVLPPIFPNLLVNGSSGIAVGMATNIPPHNLRE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 221 VAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVNTEEIKGRMCLVVTELPYQ 300
Cdd:cd00187 161 VIDALRALIDNPEASIDELME----IIKGPDFPTGGIIEGRAGIREAYETGRGRYIIRGKYEIEDDEGRNTIEITELPYQ 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 301 VNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQLQQTFGANMLALV-DGVPRTL 379
Cdd:cd00187 237 VNKAKLKEKIAELVKDKKIEGISDVRDE-SDREGIRFVIELKRGAMAEVVLNGLYKVTKLQTTFGINMVAFDpNGRPKKL 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 380 SLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSqgrEDARPKLME---FLDIDQVQAD 456
Cdd:cd00187 316 NLKEILQEFLDHRLEVYTRRKEYELGKAEARLHILEGLLKAILNIDEVINLIRSS---DEAKKALIEeleKLGFSEIQAD 392
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|...
gi 781870637 457 AILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEI 509
Cdd:cd00187 393 AILDMRLRRLTKLEREKLLKELKELEAEIEDLEKILASEERPKDLWKEELDEF 445
|
|
| TOP4c |
smart00434 |
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC |
42-499 |
0e+00 |
|
DNA Topoisomerase IV; Bacterial DNA topoisomerase IV, GyrA, ParC
Pssm-ID: 214660 [Multi-domain] Cd Length: 444 Bit Score: 631.14 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 42 RDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLV 121
Cdd:smart00434 1 IDIEDFINKEYLDYSMSVINGRAIPDVRDGLKPVQRRILYAMFKRGLTPDEPKVKSARGVGDVMGKYHPHGDSSLYDTIV 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 122 RMAQSWSMRYMLVDGQGNFGSPGD-DPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCN 200
Cdd:smart00434 81 RMAQDFSNNYPLLDGQGNFGSRLDgDDAAAMRYTETRLSPLARLLLPDIDKDTVDFVPNYDGQEIEPTVLPPIIPNLLVN 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 201 GSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDnlirIIKGPDFPTGATILGHKGieqayrtgrglITMRAV 280
Cdd:smart00434 161 GSSGIAVGMATNIPPHNLREVIDAVRRLIDNPDASIDELMM----IPWGPDFPTGGEIVGPGK-----------YVVRGK 225
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 281 VNTEEIKGrmcLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDETSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQL 360
Cdd:smart00434 226 IEIEDDNT---IVITELPYQVNTADLIEKIAELVKDKKIEGIIDVRDESHDRTGVRIVIELKRGAMAEVVLNGLYKLTKL 302
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 361 QQTFGANMLALVD-GVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAE-ERDHILQGLLKALDAIEEVIKLIRSSQ-GR 437
Cdd:smart00434 303 QTTFSINMLALFDnGRPKKYNLKEILKEFLDHRLEVYTRRKEYLLGKLEaERLHILEGLFIALSIIDEIIVLIRSSKdLA 382
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 781870637 438 EDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQR 499
Cdd:smart00434 383 KEAKEKLMERFELSEIQADAILDMRLRRLTKLEVEKLEKELKELEKEIEDLEKILASEEWLN 444
|
|
| PRK13979 |
PRK13979 |
DNA topoisomerase IV subunit A; Provisional |
44-849 |
0e+00 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 237576 [Multi-domain] Cd Length: 957 Bit Score: 620.20 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 44 LQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVRM 123
Cdd:PRK13979 18 LEEAMPENYLPYAVEVAKDRALPDVRDGLKPVHRRILYGAYMLKAFPDKPYYKSARIVGDILGKYHPHGDSSVYDAMVIL 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 124 AQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSS 203
Cdd:PRK13979 98 AQDFTTRMPLIDGHGNWGSIDGDSAAAMRYTEARLTPIAMEMLRDIDKDVVNMVDNYSDSEKEPEVLPARYPNLLVNGAF 177
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 204 GIAVGMATNIPPHNMREVAEGVHWALDHPEASREELLDNliriIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVNT 283
Cdd:PRK13979 178 GIAVGLATNIPPHNLKEVIDGTLAYIDNNEITTKELMNY----IKGPDLPTGGILIGKKSLLSAYETGEGKVTLRAKTKI 253
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 284 EEI-KGRMCLVVTELPYQVNPDRLVASIREAVRDGK----IQGIADMRDEtSGRTGQRLVLVLKRDAVPKV---VLNNLY 355
Cdd:PRK13979 254 EKLeNGRLGIVITEFPYRRNKAKLLQTISEMTADKKhskaLENISDIRDE-SDRNGIRAVIEFKKSADEDVaekVLKYLY 332
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTaylKRE---AEERDHILQGLLKALDAIEEVIKLIR 432
Cdd:PRK13979 333 KKTDLQCNISFNMVALADGKPETMGLKTMLKHYVEHQKEVVTRRT---KKEleiAEKRFHIVEGFIKAIGIMDEIIKTIR 409
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 433 SSQGREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAK 512
Cdd:PRK13979 410 SSKSKKDASENLIEKFGFTDEQAEAILELMLYRLTGLEIVAFEKEYKELEKLIKKLTKILSSEKELLKVIKKELKEVKEK 489
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 513 YGDERRTKILPYSGE--MNVEDLIPEENVVVTVTHSGFIKRTKADEYraqHRGGKGIKGAKLREDDVVDHFFLTSTHNWL 590
Cdd:PRK13979 490 YGDERRTSIIEDDEKakIDVEELIVVEDVVITLSNEGFIKRIPLKSY---NRSNSNVEDIEYREGDFNKFLIQSNTKDTL 566
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 591 LFFTNKGRVYRLKAYELPEGSRDSKGQHVANLLQfGPD---ETIQTVLSIPNYEVAKYLVLATRSGKVKKTALAEYDSpR 667
Cdd:PRK13979 567 LIFTDKGNMYQIKGINIPEFKWKEKGERLDEIIK-GIDlesEKIIEAYSIEDFTPQKDFIFITDSGGIKKTSLDKFVT-N 644
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 668 QGGLIAVRLMTDEngenadELIGAAL--CNADDDIMLVSRKgMSLKFTANDEQLRPMGRQTAGVQGMKFRDGDELLAMDV 745
Cdd:PRK13979 645 YTKLMALKLKKGE------KLIKVKLvdRTREEKFIKIKTK-KGLSFTVEEPELEPVDRNIIGYQLFDLLPNDSIKKVDF 717
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 746 -------------------------------VWGDSDKDLLVVTDEGFAKRsaVSEYRLQGRNGYGVKALQLAEGRGS-- 792
Cdd:PRK13979 718 cdnyeykefyvninkkgiikisdkdnkssisVFTNSSKNLLIFSDEGKVYK--IPAFMLQNIKNEGINISALTGDFEKde 795
|
810 820 830 840 850 860
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 781870637 793 -LVGALIVS---EDDQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLAkpDKNDEIISIALN 849
Cdd:PRK13979 796 kIIKIISIFefeEDLSIYFFSKKGLVKKTLLNEFKGEGNSTQAYKFK--HKEDELVNVDIK 854
|
|
| DNA_topoisoIV |
pfam00521 |
DNA gyrase/topoisomerase IV, subunit A; |
63-507 |
0e+00 |
|
DNA gyrase/topoisomerase IV, subunit A;
Pssm-ID: 459843 [Multi-domain] Cd Length: 432 Bit Score: 613.02 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 63 RALPDVRDGMKPVHRRVVYAMYDGgYRPDRGYSKCARVVGEVMGKYHPHGDSAIYDTLVRMAQSWSMRYMLVDGQGNFGS 142
Cdd:pfam00521 1 RAIPDVRDGLKPVQRRILYAMFEL-LNLDKPYKKVARLVGDVMGKYHPHGDASLYDAIVRMAQDFVGNIPLLDGQGNFGS 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 143 -PGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPHNMREV 221
Cdd:pfam00521 80 rIDGDKDAAMRYTETRLSKIARELFPDIDDDTVDYVPNYDGTEVEPTVLPPIIPNLLVNGAEGIAVGMATNIPPHNLREI 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 222 AEGVHWALDHPEASReelldnLIRIIKGPDFPTGATILGHKGIEQAYRTGRGLITMRAVVNTEEikgRMCLVVTELPYQV 301
Cdd:pfam00521 160 IDALIALLDGPEATL------LMKYIMGPDFPTGGGIIGKGGIKEAYKTGRGKITVRAKVEIED---RKTIVITELPYGV 230
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 302 NPDRLVASIREAVRDGKIQGIADMRDETSgrTGQRLVLVLKRDAVPKVVLNNLYKHSQLQQTFGANMLALVDGVPRTLSL 381
Cdd:pfam00521 231 WTSDLIEKIEELVKNGKIKGISDIRDESD--RGVRIVIELKRGADPEVVLNDLYKKTKLQTSFSTNNLVLFDGGPKYLGL 308
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 382 DAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQGREDARPKLMEflDIDQVQADAILSM 461
Cdd:pfam00521 309 KEILKEFLDHRLEVYERRKEYLLEKLEERLHILEGLLIALNNIDFVIEIIRGSIDRKKAKKNLIE--ELSEIQADYLLDM 386
|
410 420 430 440
....*....|....*....|....*....|....*....|....*.
gi 781870637 462 QLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELD 507
Cdd:pfam00521 387 RLRRLTKEEVDKLLEEIDELEKEIAELEKLLASEKKLNDLWIEELD 432
|
|
| parC_Gpos |
TIGR01061 |
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II ... |
39-786 |
0e+00 |
|
DNA topoisomerase IV, A subunit, Gram-positive; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273422 [Multi-domain] Cd Length: 738 Bit Score: 604.10 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 39 IQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYD 118
Cdd:TIGR01061 1 IFNKPLEEVFGESFGKYAKYIIQDRALPDIRDGLKPVQRRILYAMFQDGNTFDKPYKKSARTVGEIMGKYHPHGDSSIYD 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 119 TLVRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNLL 198
Cdd:TIGR01061 81 AMVRMSQDWKNNWTLVEMHGNNGSIDGDNAAAMRYTEARLSLIASELLKDIDKKTVSFIPNFDDSEKEPTVLPALFPNLL 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 199 CNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASreelLDNLIRIIKGPDFPTGATILGHKGIEQAYRTGRGLITMR 278
Cdd:TIGR01061 161 INGATGIAAGYATNIPPHNLNEVIDALIYRIDHPNCS----VDKLMEIVKGPDFPTGGIIQGEDGISKAYETGKGKFIIR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 279 AVVNTEEIK-GRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtSGRTGQRLVLVLKRDAVPKVVLNNLYKH 357
Cdd:TIGR01061 237 AKIEIEVNKnGLNQIVITEIPYETNKANIVKKIEEIIFDNKVAGIEEVRDE-SDRNGIRIIIELKKDANAEKILNFLFKH 315
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 358 SQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSSQGR 437
Cdd:TIGR01061 316 TDLQINYNFNMVAIANRTPIQVGLLSYLDAYIKHCHEVIINRSKYELEKASKRLEIVEGLIKAISIIDEIIKLIRSSEDK 395
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 438 EDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYGDER 517
Cdd:TIGR01061 396 SDAKENLIDNFKFTENQAEAIVSLRLYRLTNTDIFELKEEQNELEKKIISLEQIIASEKARNKLLKKQLEEYKKQFAQQR 475
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 518 RTKILPY--SGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAQHrggkgIKGAKLREDDVVDHFFLTSTHNWLLFFTN 595
Cdd:TIGR01061 476 RSQIEDFinQIKINESELIENEDYYVLITKAGYIKRTSNRSFASSK-----YTDFGSKDDDILFAQTIANTTDQILIFTS 550
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 596 KGRVYRLKAYELPEGSRDSKGQHVANLLQFGPDETIQTVLSIPNYEV-AKYLVLATRSGKVKKTALAEYDSPRQGGLIAV 674
Cdd:TIGR01061 551 LGNIINIPVHKLADIRWKDLGEHLSNKITFDENETIVFVGTMNEFDVdQPILVLASKLGMVKRIELTELNIKRNSKATLC 630
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 675 RLMTDEngenaDELIGAALCNADDDIMLVSRKGMSLKFtaNDEQLRPMGRQTAGVQGMKFRDGDELLAmdVVWGDSDKDL 754
Cdd:TIGR01061 631 IKLKDK-----DHLISAFLQQKDKLICLVSDLGYALVF--HTNEIPVVGAKAAGVKGMKLKEDDQVKS--GVIFEANESL 701
|
730 740 750
....*....|....*....|....*....|..
gi 781870637 755 LVVTDEGFAKRSAVSEYRLQGRNGYGVKALQL 786
Cdd:TIGR01061 702 VLLTQRGSVKRLSISELVVTSRAATGKKLLPL 733
|
|
| parC_Gneg |
TIGR01062 |
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II ... |
39-654 |
3.72e-166 |
|
DNA topoisomerase IV, A subunit, proteobacterial; Operationally, topoisomerase IV is a type II topoisomerase required for the decatenation of chromosome segregation. Not every bacterium has both a topo II and a topo IV. The topo IV families of the Gram-positive bacteria and the Gram-negative bacteria appear not to represent a single clade among the type II topoisomerases, and are represented by separate models for this reason. [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 130134 [Multi-domain] Cd Length: 735 Bit Score: 501.75 E-value: 3.72e-166
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 39 IQVRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEVMGKYHPHGDSAIYD 118
Cdd:TIGR01062 1 IENIDLGNFTEEAYLNYSMYVIMDRALPFIGDGLKPVQRRIVYAMSELGLNANAKYKKSARTVGDVLGKYHPHGDSACYE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 119 TLVRMAQSWSMRYMLVDGQGNFGSPGD-DPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLPNYDGKTQEPTVLPARFPNL 197
Cdd:TIGR01062 81 AMVLMAQPFSYRYPLVDGQGNWGAPDDpKSFAAMRYTESRLSKISELLLEELGQGTVDFRPNFDGTLLEPVILPARLPNI 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 198 LCNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASreelLDNLIRIIKGPDFPTGATILGHKG-IEQAYRTGRGLIT 276
Cdd:TIGR01062 161 LLNGTTGIAVGMATDIPPHNLHELADAALYLIDNPKAG----LDDILNIVQGPDFPTEAEIIDKAEeIRKIYETGRGSFR 236
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 277 MRAVVNTEEIKgrmcLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDETSGRTGQRLVLVLKRDAV-PKVVLNNLY 355
Cdd:TIGR01062 237 MRARWKKEDGQ----IVISALPHQISKSKVIEQIAIQMKDKKLPMISDIRDESDHENPIRVVIVPRSNRVdPDIVMEHLF 312
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLAL-VDGVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDAIEEVIKLIRSs 434
Cdd:TIGR01062 313 ATTDLEKSYRLNMNMIgLDNVPAVKNLLEILQEWLVFRRNTVIRRLTYRLNKVLQRLHILEGLRIAFLNIDEVIEIIRE- 391
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 435 qgREDARPKLMEFLDIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKPERQRRIVGDELDEIVAKYG 514
Cdd:TIGR01062 392 --EDEPKTILMERFKLSAIQAEAILNLRLRHLAKLEEHAIIDEQSELEKERAILEKILKSERELNQLVKKEIQADATKYG 469
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 515 DERRTKI--LPYSGEMNVEDLIPEENVVVTVTHSGFIKRTKADEYRAqhrggkgiKGAKLREDDVVDHFFLTSTHNWLLF 592
Cdd:TIGR01062 470 LARRSSLeeREEAKQVSEIDMIPKEPVTIILSKMGWVRSAKGHDIDL--------STLKYKAGDSEKAIIEGKSNQKVVF 541
|
570 580 590 600 610 620
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 781870637 593 FTNKGRVYRLKAYELPEGSrdSKGQHVANLLQFGPDETIQTVLSipnYEVAKYLVLATRSGK 654
Cdd:TIGR01062 542 IDSTGRSYALDPDNLPSAR--GQGEPLTGKLLLPIGATITNILM---YSPNQLLLMASDAGY 598
|
|
| PRK09631 |
PRK09631 |
DNA topoisomerase IV subunit A; Provisional |
43-521 |
3.82e-78 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 236598 [Multi-domain] Cd Length: 635 Bit Score: 266.57 E-value: 3.82e-78
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 43 DLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYA---MYDGGYRpdrgysKCARVVGEVMgKYHPHGDSAIYDT 119
Cdd:PRK09631 3 DIKTLFKDNFLQYASYVIKDRAIPDVIDGLKPVQRRILHSlfeMHDGKFH------KVANVVGNTM-KYHPHGDASIYEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 120 LVRMAQswsmRYMLVDGQGNFGSP-GDDPAAAMRYTECRMAPLAMEMVrdIDKDTVDFLPNYDGKTQEPTVLPARFPNLL 198
Cdd:PRK09631 76 LVNLAN----KDLFIDKQGNFGNLfTGDPASAARYIECRLTPLAKEVL--YNKEITEYEPSYDGRNNEPLCLPAKIPVIL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 199 CNGSSGIAVGMATNIPPHNMREVAegvhwaldhpEASREELLDNLIRIIkgPDFPTGatilghkGI--EQAYRTGRGLIT 276
Cdd:PRK09631 150 IQGAEGIAVGMATKILPHNFNEIL----------QAVKSELLGESFALY--PDFPTG-------GIvdVSEYADGNGKVL 210
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 277 MRAVVNTEEIKGrmcLVVTELPYQVNPDRLVASIREAVRDGKIQgIADMRDETSGRTgqRLVLVLKRDAVPKVVLNNLYK 356
Cdd:PRK09631 211 VRAKIETKDEKT---IVIREIPFGTTTESLIASIEKAARKGKIK-ISSINDYTAENV--EIEIKLPRGVYASEVIEALYA 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 357 HSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQidvvarrTAYLKREAE-ERDHILQGL-LKALDAI---EEVIKLI 431
Cdd:PRK09631 285 YTDCEVSISVNLLVIKDRYPVIYTVTDIIKFHAEHL-------QKVLKMELElERAKLLEKIfAKTLEQIfieERIYKRI 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 432 RSSQGREDARPKLMEFL---------DIDQVQADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILakperqRRIV 502
Cdd:PRK09631 358 ETISSEEDVISIVLSELkpfkeelsrDVTEEDIENLLKIPIRRISLFDIDKNQKEIRILNKELKSVEKNL------KSIK 431
|
490 500
....*....|....*....|....
gi 781870637 503 G---DELDEIVAKYGDE--RRTKI 521
Cdd:PRK09631 432 GyaiNFIDKLLAKYSKEypRKTEI 455
|
|
| PRK12758 |
PRK12758 |
DNA gyrase/topoisomerase IV subunit A; |
52-521 |
4.64e-55 |
|
DNA gyrase/topoisomerase IV subunit A;
Pssm-ID: 237192 [Multi-domain] Cd Length: 869 Bit Score: 205.62 E-value: 4.64e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 52 YLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYdggyRPDRG-YSKCARVVGEVMgKYHPHGDSAIYDTLVRMAQswsmR 130
Cdd:PRK12758 31 FLDYASYVILERAVPHIEDGLKPVQRRILHSMK----EMDDGrYNKVANVVGHTM-QYHPHGDASIGDALVQLGQ----K 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 131 YMLVDGQGNFGSP--GDDpAAAMRYTECRMAPLAMEMVrdIDKDTVDFLPNYDGKTQEPTVLPARFPNLLCNGSSGIAVG 208
Cdd:PRK12758 102 DLLIDTQGNWGNIltGDG-AAAPRYIEARLSKFALEVV--FNPKTTEWQLSYDGRKKEPVTLPVKFPLLLAQGAEGIAVG 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 209 MATNIPPHNMRevaegvhwaldhpeasreELLDNLIRIIKG------PDFPTGATI------LGHKGieqayrtgrGLIT 276
Cdd:PRK12758 179 LSTKILPHNFN------------------ELIDASIAYLKGkefklyPDFPTGGIIdvsnynDGERG---------GRVR 231
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 277 MRAVVNTEEIKgrmCLVVTELPYQVNPDRLVASIREAVRDGKIQgIADMRDETSGRTGqrlVLV-LKRDAVPKVVLNNLY 355
Cdd:PRK12758 232 VRAKIEKLDKK---TLVITEIPYGTTTSSLIDSILKANDKGKIK-IKKVEDNTAADVE---ILVhLAPGVSPDKTIDALY 304
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLALVDGVPRTLSLDAFIRHWINHQIDVvarrtayLKREAE-ERDHILQGLLKA-LDAI---EEVIKL 430
Cdd:PRK12758 305 AFTDCEVSISPNACVIIDNKPHFLGVSDILRRSTDHTVSL-------LKQELEiRLSELEEQWHFAsLEKIfieERIYKE 377
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 431 IRSSQGREDArpklMEFLD----------IDQVQADAIlsmqlVRLANMEAQKI----VDEHNELMRKIadyndilakpE 496
Cdd:PRK12758 378 IEEAETWEAV----IEAIDkglepfkkqfIREVTEDDI-----VRLTEIKIKRIskfdSDKADELIARL----------E 438
|
490 500 510
....*....|....*....|....*....|....*...
gi 781870637 497 RQRRIVGDELDEIVA-----------KYGD--ERRTKI 521
Cdd:PRK12758 439 AEIAEVKHHLAHLTDyaiayftnlkkKYGKgrERKTEI 476
|
|
| PRK09630 |
PRK09630 |
DNA topoisomerase IV subunit A; Provisional |
41-525 |
3.68e-50 |
|
DNA topoisomerase IV subunit A; Provisional
Pssm-ID: 170022 Cd Length: 479 Bit Score: 184.33 E-value: 3.68e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 41 VRDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYdggyRPDRG-YSKCARVVGEVMGkYHPHGDSAIYDT 119
Cdd:PRK09630 1 MSDVSDLFKTHFMHYASYVILERAIPHILDGLKPVQRRLLWTLF----RMDDGkMHKVANIAGRTMA-LHPHGDAPIVEA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 120 LVRMAQswsmRYMLVDGQGNFGSP-GDDPAAAMRYTECRMAPLAMEMVrdIDKDTVDFLPNYDGKTQEPTVLPARFPNLL 198
Cdd:PRK09630 76 LVVLAN----KGYLIDTQGNFGNPlTGDPHAAARYIEARLSPLAKEVL--FNTDLMTFHDSYDGREKEPDILPAKLPLLL 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 199 CNGSSGIAVGMATNIPPHNMREVAEGVHWALDHPEASreeLLdnliriikgPDFPTGATILGHKgieqaYRTGRGLITMR 278
Cdd:PRK09630 150 LHGVDGIAVGMTTKIFPHNFCELLEAQIAILNDQPFT---LL---------PDFPSGGTMDASE-----YQDGLGSITLR 212
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 279 AVVNTEEIKgrmCLVVTELPYQVNPDRLVASIREAVRDG--KIQGIADMRDETSgrtgqRLVLVLKRDAVPKVVLNNLYK 356
Cdd:PRK09630 213 ASIDIINDK---TLLIKEICPSTTTETLIRSIENAAKRGiiKIDSIQDFSTDLP-----HIEIKLPKGIYAKDLLRPLFT 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 357 HSQLQQTFGANMLALVDGVPRTLSLDAFIRhwinHQIDVVarrTAYLKREAE------ERDHILQGL------LKALDAI 424
Cdd:PRK09630 285 HTECQVILTSRPTAIYQNKPVETSISEILR----LHTETL---QGYLKKELLiledslSREHYHKTLeyifikHKLYDTV 357
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 425 EEVIKLIRSSQGREDARPKLMEFLDIDQVQADAILSMQLV-RLANMEAQKIV--DEHNelmrkiadYNDILAKPERQRRI 501
Cdd:PRK09630 358 REMLSKRKTSPSSSDLHNAVLEALTPFLDTLPTPVDKQATaQLASLTIKKILcfNENS--------YTKELACIEKKQAA 429
|
490 500 510
....*....|....*....|....*....|....*..
gi 781870637 502 VGDELDEI-----------VAKYGD--ERRTKILPYS 525
Cdd:PRK09630 430 VQKDLSQLkkytvkylkglLETYGQlgHRKTQIAKFK 466
|
|
| 52 |
PHA02592 |
DNA topisomerase II medium subunit; Provisional |
42-481 |
1.23e-47 |
|
DNA topisomerase II medium subunit; Provisional
Pssm-ID: 222896 [Multi-domain] Cd Length: 439 Bit Score: 176.02 E-value: 1.23e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 42 RDLQTEMRESYLAYAMSVIVDRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEV-MGKYHpHGDSAIYDTL 120
Cdd:PHA02592 6 RSLKSIVNNEALEYAMYTVEERAIPNLIDGLKPVQRFVIHRALEYAKGNKEKFDKVAAIAGGVaDLGYH-HGETSAQDAG 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 121 VRMAQSWSMRYMLVDGQGNFGSPGDDPAAAMRYTECRMAPLamemVRDIDKDTvDFLPNYdgktQEPTVLPARF-----P 195
Cdd:PHA02592 85 ALMANTWNNNIPLLDGQGNFGSRLVQKAAAARYIFARVHDN----FRKIYKDE-DLAPVH----EDPEHIPPAFylpiiP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 196 NLLCNGSSGIAVGMATNIPPHNMREVAEGVHWALdhpeasREELLDNLIriikgPDFPtgatilGHKGieQAYRTGRGLI 275
Cdd:PHA02592 156 MVLLNGVSGIATGYATNILPHSPKSVIKAVLAAL------NGKDITEPK-----VQFP------EFKG--EVVEIEPGSY 216
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 276 TMRAvvnTEEIKGRMCLVVTELPYQVNPDRLVASIREAVRDGKIQGIADMRDEtsgrtGQRLVLVLKRDAVPKVVLNNLY 355
Cdd:PHA02592 217 EIRG---TYELNGKTKLHITEIPVKYDRETYVAVLDPLEEKGKIVSYDDCTED-----GFRFKVTLKREENEEATHEKIM 288
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 356 KHSQLQQTFGANMLALV-DGV------PRTLsldafIRHWINHQIDVVARRTAYLKREAEERdhiLQGLLKALDAIEEVI 428
Cdd:PHA02592 289 KDFGLIERVSQNITVINeNGKlkvyenAEDL-----IRDFVEIRKTYVQKRIQYEIKETEEA---FDLALAKAEFIKRVI 360
|
410 420 430 440 450
....*....|....*....|....*....|....*....|....*....|....*.
gi 781870637 429 KLIRSSQGREDArpKLMEFL---DIDQVQADAILSMQLVRLANMEAQKIVDEHNEL 481
Cdd:PHA02592 361 AGEIVLQGKTRS--ELTEELsdnKDFGEYADKLVAMNIYSMTSDEREKLQKEAEEL 414
|
|
| PTZ00108 |
PTZ00108 |
DNA topoisomerase 2-like protein; Provisional |
63-533 |
5.82e-20 |
|
DNA topoisomerase 2-like protein; Provisional
Pssm-ID: 240271 [Multi-domain] Cd Length: 1388 Bit Score: 95.88 E-value: 5.82e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 63 RALPDVRDGMKPVHRRVVYAMYDggyRPDRGYSKCARVVGEVMGK--YHpHGDSAIYDTLVRMAQSW----SMRYMLVDG 136
Cdd:PTZ00108 680 RSIPSLVDGLKPGQRKILFACFK---RNLKNEIKVAQLSGYVSEHsaYH-HGEQSLQQTIVGMAQNFvgsnNINLLYPCG 755
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 137 QgnFGSP---GDDPAAAmRYTECRMAPLAmemvRDIDKDTVDFLPNY---DGKTQEPTVLPARFPNLLCNGSSGIAVGMA 210
Cdd:PTZ00108 756 Q--FGSRlqgGKDHAAA-RYIFTKLSKIT----RYIFPEEDDPILDYledDGQSVEPFYYVPIIPMVLVNGAEGIGTGFS 828
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 211 TNIPPHNMREVaegvhwaldhpeasreelLDNLIRIIKGPDFPTgatiL-----GHKGIEQAYRTGRGLITMRAVVNTEE 285
Cdd:PTZ00108 829 TSIPNYNPLDI------------------IDNLRRRLNGEEVRP----LvpwyrGFKGTIERNPKGKFISKGIYEKVPDG 886
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 286 IkgrmcLVVTELPYQvnpdRLVASIREAVRDGKIQG---IADMRDETSGRTgQRLVLVLKRDAVPKVVLNNLYKHSQLQQ 362
Cdd:PTZ00108 887 T-----VEITELPIG----KWTEDYKEFLESETLKEkdvIVDYRDYSTANT-VHFTVKLNDGVLEQWEEEGIEKVFKLKS 956
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 363 TFGANMLALVD---GVPRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQGLLKALDA-IEEVIKLIRSSqgRE 438
Cdd:PTZ00108 957 TISTTNMVLFDengKIKKYSDALDILKEFYLVRLDLYKKRKEYLLGKLERELARLSNKVRFIKHvINGELVITNAK--KK 1034
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 439 DARPKL--MEFLDIDQVQ--ADAILSMQLVRLANMEAQKIVDEHNELMRKIADYNDILAKP------ERQRRIVgDELDE 508
Cdd:PTZ00108 1035 DLVKELkkLGYVRFKDIIkkKSEKITAEEEEGAEEDDEADDEDDEEELGAAVSYDYLLSMPiwsltkEKVEKLN-AELEK 1113
|
490 500
....*....|....*....|....*
gi 781870637 509 IVAKYGDERRTKILpysgEMNVEDL 533
Cdd:PTZ00108 1114 KEKELEKLKNTTPK----DMWLEDL 1134
|
|
| PLN03128 |
PLN03128 |
DNA topoisomerase 2; Provisional |
62-497 |
8.00e-19 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215593 [Multi-domain] Cd Length: 1135 Bit Score: 92.08 E-value: 8.00e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 62 DRALPDVRDGMKPVHRRVVYAMYDGGYRPDRGYSKCARVVGEvMGKYHpHGDSAIYDTLVRMAQSW--SMRYMLVDGQGN 139
Cdd:PLN03128 672 ARSIPSMVDGLKPSQRKVLFACFKRNLKSEIKVAQLSGYVAE-HSAYH-HGEASLASTIIGMAQDFvgSNNINLLTPSGQ 749
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 140 FGSP---GDDPAAAmRYTECRMAPLAMEMVRDIDKDTVDFLpNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPH 216
Cdd:PLN03128 750 FGTRlqgGKDAASA-RYIFTRLSPITRALFPKDDDVLLNYL-NEDGQSIEPEWYCPIIPMVLVNGSEGIGTGWSTFIPNY 827
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 217 NMREVaegvhwaldhpeasreelLDNLIRIIKGPDF-PTGATILGHKG-IEQAYRTGRGLITMRAVVnteEIKGRMCLVV 294
Cdd:PLN03128 828 NPRDI------------------IANIRRLLRGEELePMHPWYRGFKGtITEVSTSRSGSYTVTGII---EQIGDTTIRI 886
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 295 TELPYQVNPDRLVASIREAVRDGKIQG--IADMRdETSGRTGQRLVLVLKRDAVPKVVLNNLYKHSQLQQTFG-ANMLAL 371
Cdd:PLN03128 887 TELPVRKWTQDYKEFLEALLTGTKKKEpeIKDFK-ENHTDTTVHFTVTLSEEKMARALAEGLEKKFKLSTTIStSNMHLF 965
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 372 -VDGV-PRTLSLDAFIRHWINHQIDVVARRTAYLKREAEERDHILQ----------------GLLKALDAIEEVIKLIRS 433
Cdd:PLN03128 966 dKDGKiKKYDSPEDILEEFFHLRLDLYVKRKEVLLENLEYELKKLDnkarfilavvkgeivvNNRKRAELLAELEEKGFD 1045
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 781870637 434 SQGREDARPKL------MEFLDIDQVQADAILSMQLVRLANMEAQKIVDEH-NELMRKIADYNDILAKPER 497
Cdd:PLN03128 1046 KFPKTAKISETnvvgdrDGEASEEEEASDNELAKSYDYLLGMPISSLTLEKvDELRAERAKKETEVEELKK 1116
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
63-230 |
4.76e-15 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 79.91 E-value: 4.76e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 63 RALPDVRDGMKPVHRRVVYAMYDGGYRPDrgySKCARVVGEV--MGKYHpHGDSAIYDTLVRMAQ----SWSMRYMLVDG 136
Cdd:PLN03237 698 RSIPSMVDGLKPGQRKILFCSFKRNFVKE---AKVAQLSGYVseHSAYH-HGEQSLASTIIGMAQdfvgSNNINLLLPNG 773
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 781870637 137 QGNFGSPGDDPAAAMRYTECRMAPLAMEMVRDIDKDTVDFLpNYDGKTQEPTVLPARFPNLLCNGSSGIAVGMATNIPPH 216
Cdd:PLN03237 774 QFGTRLQGGKDHASARYIFTRLSPITRFLFPKDDDILLDYL-NEDGQSIEPTWYMPIIPTVLVNGAEGIGTGWSTFIPNY 852
|
170
....*....|....
gi 781870637 217 NMREVAEGVHWALD 230
Cdd:PLN03237 853 NPRDIVANIRRLLN 866
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
540-585 |
5.99e-12 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 60.96 E-value: 5.99e-12
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 781870637 540 VVTVTHSGFIKRTKADEYRAQHRGGKGIKGAKLREDDVVDHFFLTS 585
Cdd:pfam03989 3 LLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
752-800 |
1.12e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 54.42 E-value: 1.12e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 781870637 752 KDLLVVTDEGFAKRSAVSEYRLQGRNGYGVKALQLAEGrGSLVGALIVS 800
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEG-DKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
698-746 |
3.66e-09 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 53.26 E-value: 3.66e-09
10 20 30 40
....*....|....*....|....*....|....*....|....*....
gi 781870637 698 DDIMLVSRKGMSLKFTANDeqLRPMGRQTAGVQGMKFRDGDELLAMDVV 746
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSE--IREQGRGAKGVKGINLKEGDKVVSVLVV 47
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
588-638 |
1.16e-08 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 51.72 E-value: 1.16e-08
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|.
gi 781870637 588 NWLLFFTNKGRVYRLKAYELPEGSRDSKGQHVANLlqfGPDETIQTVLSIP 638
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINL---KEGDKVVSVLVVN 48
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
803-848 |
1.01e-06 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 46.33 E-value: 1.01e-06
10 20 30 40
....*....|....*....|....*....|....*....|....*.
gi 781870637 803 DQVMAIMKSGKVIRSDVAEVKRTGRNTQGVTLAKPDKNDEIISIAL 848
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGAKGVKGINLKEGDKVVSVLV 46
|
|
| DNA_gyraseA_C |
pfam03989 |
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the ... |
644-695 |
1.83e-03 |
|
DNA gyrase C-terminal domain, beta-propeller; This repeat is found as 6 tandem copies at the C-termini of GyrA and ParC DNA gyrases. It is predicted to form 4 beta strands and to probably form a beta-propeller structure. This region has been shown to bind DNA non-specifically and may stabilize the DNA-topoisomerase complex.
Pssm-ID: 427633 [Multi-domain] Cd Length: 48 Bit Score: 37.08 E-value: 1.83e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....
gi 781870637 644 KYLVLATRSGKVKKTALAEYDSPRQG--GLIAVRLmtdengENADELIGAALCN 695
Cdd:pfam03989 1 DELLLITSKGYVKRTPLSEIREQGRGakGVKGINL------KEGDKVVSVLVVN 48
|
|
| |
