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Conserved domains on  [gi|78170166|gb|ABB27263|]
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conserved hypothetical protein [Synechococcus sp. CC9902]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Tic20 super family cl46717
Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein ...
 1-135 2.58e-30

Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein import [Energy production and conversion];


The actual alignment was detected with superfamily member COG5769:

Pssm-ID: 444479  Cd Length: 159  Bit Score: 106.51  E-value: 2.58e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78170166   1 MPFGLGmdgLFNQIPLLRLLIVPAIPFIQLQRVVPFGGLLLFFVLFLGVVRNPNVPYFLRFNALQALLTDIVVIVLSFAF 80
Cdd:COG5769  27 LPFGIF---LFRQFPLLQILYLPLLPLIQIYYGIPFAGLIIFFVLFLAVVRNEKISHFIRFNTMQAILLDILLILCGLVL 103

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 78170166  81 SILLRPIGGDTLLVGTLSSTVVIAVLAILVFAIVECLRGREPDLPGLSQAVRMQL 135
Cdd:COG5769 104 QILGQGIPGGGLLIETLSNTIFLGTLAAVVYSIVQSLRGRYAEIPTISEAVYMQV 158
 
Name Accession Description Interval E-value
Tic20 COG5769
Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein ...
 1-135 2.58e-30

Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein import [Energy production and conversion];


Pssm-ID: 444479  Cd Length: 159  Bit Score: 106.51  E-value: 2.58e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78170166   1 MPFGLGmdgLFNQIPLLRLLIVPAIPFIQLQRVVPFGGLLLFFVLFLGVVRNPNVPYFLRFNALQALLTDIVVIVLSFAF 80
Cdd:COG5769  27 LPFGIF---LFRQFPLLQILYLPLLPLIQIYYGIPFAGLIIFFVLFLAVVRNEKISHFIRFNTMQAILLDILLILCGLVL 103

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 78170166  81 SILLRPIGGDTLLVGTLSSTVVIAVLAILVFAIVECLRGREPDLPGLSQAVRMQL 135
Cdd:COG5769 104 QILGQGIPGGGLLIETLSNTIFLGTLAAVVYSIVQSLRGRYAEIPTISEAVYMQV 158
TIC20 pfam16166
Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear ...
 3-130 4.02e-07

Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.


Pssm-ID: 374405  Cd Length: 177  Bit Score: 46.63  E-value: 4.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78170166     3 FGLGMDGLFNQIPLLRLLIVPAIPFIQLQRVvpFGGLLLFFVLFLGVVRNPNVPYFLRFNALQALLTDIVVIVLSFAfSI 82
Cdd:pfam16166  52 TGYYLHPFLEQFPPFGLLIYPIPGAINRLPS--WFSMVYFFTLYFGVVRNKNLPHYFRFHVMMAMLLDVLLQVVLLT-SN 128

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 78170166    83 LLRPIGGDTLLVGTLSSTVVIAVLAILVFAIVECLRGREPDLPGLSQA 130
Cdd:pfam16166 129 FNPLIGFGGKFGMYYWTGVFLFYIFTLLYCIRCALAGMYPRIPFVSEA 176
 
Name Accession Description Interval E-value
Tic20 COG5769
Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein ...
 1-135 2.58e-30

Cyanobacterial/chloroplast membrane protein Tic20/Ycf60, involved in chloroplast protein import [Energy production and conversion];


Pssm-ID: 444479  Cd Length: 159  Bit Score: 106.51  E-value: 2.58e-30
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78170166   1 MPFGLGmdgLFNQIPLLRLLIVPAIPFIQLQRVVPFGGLLLFFVLFLGVVRNPNVPYFLRFNALQALLTDIVVIVLSFAF 80
Cdd:COG5769  27 LPFGIF---LFRQFPLLQILYLPLLPLIQIYYGIPFAGLIIFFVLFLAVVRNEKISHFIRFNTMQAILLDILLILCGLVL 103

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*
gi 78170166  81 SILLRPIGGDTLLVGTLSSTVVIAVLAILVFAIVECLRGREPDLPGLSQAVRMQL 135
Cdd:COG5769 104 QILGQGIPGGGLLIETLSNTIFLGTLAAVVYSIVQSLRGRYAEIPTISEAVYMQV 158
TIC20 pfam16166
Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear ...
 3-130 4.02e-07

Chloroplast import apparatus Tic20-like; Chloroplast function requires the import of nuclear encoded proteins from the cytoplasm across the chloroplast double membrane. This is accomplished by two protein complexes, the Toc complex located at the outer membrane and the Tic complex located at the inner membrane. The Toc complex recognizes specific proteins by a cleavable N-terminal sequence and is primarily responsible for translocation through the outer membrane, while the Tic complex translocates the protein through the inner membrane. This entry represents Tic20, a core member of the Tic complex. This protein is deeply embedded in the inner envelope membrane and is thought to function as a protein- conducting component of the Tic complex.


Pssm-ID: 374405  Cd Length: 177  Bit Score: 46.63  E-value: 4.02e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 78170166     3 FGLGMDGLFNQIPLLRLLIVPAIPFIQLQRVvpFGGLLLFFVLFLGVVRNPNVPYFLRFNALQALLTDIVVIVLSFAfSI 82
Cdd:pfam16166  52 TGYYLHPFLEQFPPFGLLIYPIPGAINRLPS--WFSMVYFFTLYFGVVRNKNLPHYFRFHVMMAMLLDVLLQVVLLT-SN 128

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 78170166    83 LLRPIGGDTLLVGTLSSTVVIAVLAILVFAIVECLRGREPDLPGLSQA 130
Cdd:pfam16166 129 FNPLIGFGGKFGMYYWTGVFLFYIFTLLYCIRCALAGMYPRIPFVSEA 176
COG4818 COG4818
Uncharacterized membrane protein MJ1443, UPF0132 family [Function unknown];
58-125 4.27e-03

Uncharacterized membrane protein MJ1443, UPF0132 family [Function unknown];


Pssm-ID: 443846  Cd Length: 105  Bit Score: 34.41  E-value: 4.27e-03
                        10        20        30        40        50        60
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 78170166  58 FLRFNALQALLTDIVVIVLSFAFSILLRPIGGdtllvGTLSSTVVIAVLAILVFAIVECLRGREPDLP 125
Cdd:COG4818  30 FVRFHAMQSLLLFLGLFVLSILLTLSFIPVLG-----WLISLLLGLASLVLWIVLMVKAYRGERYKLP 92
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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