|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
39-743 |
2.68e-74 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 253.98 E-value: 2.68e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 39 LDAVSVIGQGE-------TRQVQRITQQDIAVLPpGTSIQKLLNRMPGVNVQSNDAfganeESQTISLRGFNG--TRLGY 109
Cdd:COG1629 1 LEEVVVTATRTdeslqdvPGSVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAGG-----GAGQISIRGFGGggNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 110 TLDGLPLGDNAYGNYNglniSRALIAENFGGVELASGIGALgTASTSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRT 189
Cdd:COG1629 75 LVDGVPLNDPSGGDGG----LSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 190 FLRVDTGDyNGFSAYVSGINAEADMWTRPeSPTTTRQFNAKGVYQF-DGGKLTAFADTSRTSQADYAYLSKSGMARGlgw 268
Cdd:COG1629 150 SLSLSGGN-GKLAYRLSASYRDSDGYRDN-SDSDRYNLRAKLGYQLgDDTRLTLSASYSDSDQDSPGYLTLAALRPR--- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 269 dwnlyapdwnralaaaycapatrnaarcgfsGGVDNIDDAYYQSRALRDDDLFYVAGDFQP-NDAISLHTQVYHHENKGQ 347
Cdd:COG1629 225 -------------------------------GAMDDGTNPYSNDTDDNTRDRYSLSLEYEHlGDGLKLSASAYYRYDDTD 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 348 GHWWSPGQASNPGTpealpisIRSTNYWINRTGGIASLGWEL---GPHHLEAGLWYERNHHDVERNFYWITGPVSddkfl 424
Cdd:COG1629 274 LDSDFTPTPADGGT-------LEQTDFDNRTYGLELRLTYDLgfgGKHTLLVGLDYQRQDLDGSGYPLDLGSGSL----- 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 425 qNPNRRLFSQNYVITTRQFYVQGNFKFLDqRLSLDLGIKSPSTEMTARETPGVAVEAPVAtgslKASESVLPQIGLGYRL 504
Cdd:COG1629 342 -PTLTSGADDDGTTTSLALYAQDTYKLTD-KLTLTAGLRYDYVSYDVDDTVTGTDSASGS----RSYSAFSPSLGLTYQL 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 505 ADGQEVFASYAENIAAFQGGGAGGPLLVTQASFDASvgaLEPEKSRTLEAGYRV--VRDRFEASLVGYDVTFDNRLLSln 582
Cdd:COG1629 416 SPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPD---LKPETSTNYELGLRYrlLDGRLSLSLALFYSDVDNEILS-- 490
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 583 pcasIQQGTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNyvqNGVVIPTAGKYTVDTPKRMFA 662
Cdd:COG1629 491 ----VPLPNDSGFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKFDDD---TDGSADLDGNRLPGVPPLTAN 563
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 663 SELAFN-SGPWNLNLRGKYTGQRYYTYTNDQGF-GGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYASNLTAFAN 740
Cdd:COG1629 564 LGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGApGGYTLVDLGAGYRFG-----DNLTLSLGVDNLFDKKYATSLSVRAS 638
|
...
gi 780535845 741 TDP 743
Cdd:COG1629 639 NVR 641
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
53-766 |
4.96e-48 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 180.34 E-value: 4.96e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 53 VQRITQQDIAVLPPgTSIQKLLNRMPGVNVQSNDAFGAneesQTISLRGFNGTRLGYTLDGLPLGDNAYGNYNGLNIsra 132
Cdd:cd01347 2 VSVITAEDIEKQPA-TSLADLLRRIPGVSVTRGGGGGG----STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNT--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 133 LIAENFGGVELASGIGALGTAStSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTF-----LRVDTGDYNGFSAYVSG 207
Cdd:cd01347 74 IPPELIERVEVLKGPSSALYGS-GAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGgggfdVSGALADDGAFGARLYG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 208 INAEADMWTRPESPTTTRQFNAKGVYqfdgGKLTAFADTSRTSQADYAYLSksgmaRGLGWDWNLYAPDWNRALAAAYCA 287
Cdd:cd01347 153 AYRDGDGTIDGDGQADDSDEERYNVA----GKLDWRPDDDTRLTLDAGYQD-----QDADGPGGTLPANGTGSSLGGGPS 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 288 PATRNAARcgfsggvdniddayYQSRALRDDDLFYVAGDFQPNDAISLHTQVYHHENKGQGHW---WSPGQASNPGTPEA 364
Cdd:cd01347 224 SNTNGDRD--------------WDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPlilNGGNNAAGGDLGRS 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 365 LPISIRSTNYWINRTGGIASLGWELGPHHLEAGLWYERNHHDvernfywitgpvsddkflqnpnRRLFSqnyvittrqFY 444
Cdd:cd01347 290 GYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREELD----------------------EKQTA---------LY 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 445 VQGNFKFLDqRLSLDLGIKSPSTEMTARETPgvaveAPVATGSLKASEsVLPQIGLGYRLADGQEVFASYAENIAAFQGG 524
Cdd:cd01347 339 AQDTIELTD-DLTLTLGLRYDHYDQDSKDTI-----AGGTTAKKSYSH-WSPSLGLVYKLTDGLSLYASYSQGFRAPSLG 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 525 GAGgPLLVTQASFDASVGALEPEKSRTLEAGYRVVRD-RFEASLVGYDVTFDNRLlslnpcASIQQGTTPACTTRFFNVG 603
Cdd:cd01347 412 ELY-GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEI------VSTPTNTGLGLVTVYVNGG 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 604 SVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNYVQNGvviptaGKYTVDTPKRMFASELAFNSGP--WNLNLRGKYT 681
Cdd:cd01347 485 KARIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGATT------GNRLPGIPKHTANLGLDYELPDegLTAGGGVRYR 558
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 682 GQRYYTYTNDQGF---GGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYasnltaFANTDPNGRQLAFHASAPRQV 758
Cdd:cd01347 559 GKQYADTANGNNTvkvPGYTLVDLSASYQFT-----KNLTLRLGVNNLFDKDY------YTSLSVRGSGLYGYYGPGRTY 627
|
....*...
gi 780535845 759 FLTLDAKF 766
Cdd:cd01347 628 YLSVSYKF 635
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
299-765 |
1.51e-29 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 122.96 E-value: 1.51e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 299 SGGVDNIDDAYYQSRALRDDDLFYVAGDFQPNDAISLHTQVYHHENKGQGHwwspGQASNPGTPEALPISIRSTNYWINR 378
Cdd:pfam00593 41 GGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLD----GDYTSNSSGLSGAGDYLSDDRLYGL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 379 TGGIASLGWELGphhLEAGLWYERNHHDVERNFYWITGPVSDDKFLQNPNRRlFSQNYVITTRQFYVQGNFKFLDqRLSL 458
Cdd:pfam00593 117 YGLDGDLELSLD---LSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSS-SYSDTTTDSYGLYLQDNIKLTD-RLTL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 459 DLGIKSPSTEMTARETPGVAveapvaTGSLKASESVLPQIGLGYRLADGQEVFASYAENIAA-FQGGGAGGPLLVTQASF 537
Cdd:pfam00593 192 TLGLRYDHYSTDGDDGNGGG------DNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRApSLGELYGSGSGGGGGAV 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 538 DASVGALEPEKSRTLEAGYRVVRDRFEASLVGYDVTFDNRLLSLNpcasiQQGTTPACTTRFFNVGSVSSRGGELTViwk 617
Cdd:pfam00593 266 AGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDP-----DGPGLGGTVYTYTNVGKARIRGVELEL--- 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 618 ptSYLQWYNSASINRSTYDDNYVQNGVVipTAGKYTVDTPKRMF--ASELAFNSGPWNLNLRGKYTGQ---RYYTYTNDQ 692
Cdd:pfam00593 338 --SGRLWGLGLSGGGYTYTDADDDADAD--DTGNPLPNVPRHTAnlGLTYDFPLGGWGARLGARYVGSgerRYGDAANTF 413
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 780535845 693 GFGGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYASnltafaNTDPNGRQLAFHASAPRQVFLTLDAK 765
Cdd:pfam00593 414 KTPGYTLVDLSAGYRLN-----KNLTLRLGVNNLFDKYYKR------YYSSGGGNLGGYPGPGRTFYLGLSYK 475
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
53-766 |
7.02e-28 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 119.82 E-value: 7.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 53 VQRITQQDIAvLPPGTSIQKLLNRMPGVNVQSNdafGANEESQTISLRGFNGT--RLGYTLDGLPLGdnaygnyngLNIS 130
Cdd:TIGR01783 6 VSVITRQELE-DQQAGSLSEALQRVPGVVVGGS---GGTTQFGNITIRGFGLEvdIDNVYLDGVPLL---------SRGN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 131 RALIA-ENFGGVELASGIGALgTASTSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTFLRVD--TGDYNGFSAYVSG 207
Cdd:TIGR01783 73 LAIVDpAMVERVEVLRGPASL-LYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGgpLGADGTFRGRLNG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 208 INAEADMWtrpesptttRQFNAKGVYqFDGGKLTAFADTSRTSQADYAYLSksGMARGLGWDWNLYAPDWNRALAAAYCA 287
Cdd:TIGR01783 152 ARQDGDSF---------YDGAGEETR-LGATATDWQLDDRTLLRLGAYYQK--ERDRGGYGGLPASGGTSGRDLSSDRYL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 288 PATRNAarcgfsggvdNIDDAYYQSRALRDDDLF------YVAGDFQPNDAISlhtqvyhhENKGQGHWWSPGQASNPgt 361
Cdd:TIGR01783 220 GTSSNR----------NYDDREYLSYGLSLEYQFndvwtgKQNLRYSYFDTDS--------NQVQASGYSSDGGLFGR-- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 362 pealpisiRSTNYWINRTGGIASLG----WELGP--HHLEAGLWYERNHHDVERNFYWITGPVsDDKFLQNPNRRLFSQN 435
Cdd:TIGR01783 280 --------SLTVVNVKQDRVQIDAGldgeFETGPieHDLLLGVSYGQRTTNRFNNTGYPSDNI-YSLTATSSARTDIGDS 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 436 YVI--TTRQFYVQGNF----KFLDQRLSLDLGIKSPSTEMTAreTPGVAVEapvaTGSLKASEsVLPQIGLGYRLADGQE 509
Cdd:TIGR01783 351 PKDraLSSTTKALNGValqrILLADKWTLTLGGRYDSVDVKS--NNGVAGS----TGKRDDSQ-FTPSLGVAYKPTDDWS 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 510 VFASYAENIAafqgggaggPLLVTQASFDASVGALEPEKSRTLEAGYRVVR-DRFEASLVGYDVTFDNRLLSLnpcasiq 588
Cdd:TIGR01783 424 LYASYAESFK---------PGGYYPKGAGNSGDILEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD------- 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 589 qgttPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRS-TYDDNYVQNGvviptaGKYTVDTPKRMFASELAF 667
Cdd:TIGR01783 488 ----PVNGTFSVNAGKTRNRGVELEARGYLTPGLSLSAGYTYTDAeFTEDTNGDTQ------GNTVPFVPKHTASLWASY 557
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 668 NSGPWNLNL----RGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGQVgvlQGLKLSLNVTNLTDKRY---ASNLTAFAN 740
Cdd:TIGR01783 558 APPVGDNGLtlggGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKK---KNLTLALNVNNLFDRDYytsGYRWGPSAY 634
|
730 740
....*....|....*....|....*.
gi 780535845 741 TDPNgrqlafhasAPRQVFLTLDAKF 766
Cdd:TIGR01783 635 IYPG---------APRTVGLSVSYDF 651
|
|
| PRK10044 |
PRK10044 |
ferrichrome outer membrane transporter; Provisional |
538-733 |
2.07e-06 |
|
ferrichrome outer membrane transporter; Provisional
Pssm-ID: 236643 [Multi-domain] Cd Length: 727 Bit Score: 51.30 E-value: 2.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 538 DASVGALEPEKSRTLEAGYRVV-RDR-FEASLVGYDVTFDNRLLS--LNPCASIQQGttpacttrffnvgSVSSRGGELt 613
Cdd:PRK10044 520 GKDGNIFAPSKGKQYEAGVKYVpKDRpIVVTGAVYQLTKTNNLTAdpENSFFSVQGG-------------EIRARGVEL- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 614 viwKPTSYLqwynSASINRS---TYddnyvqngvvipTAGKYTVDT----------PKRMFA--SELAFNSGPWN---LN 675
Cdd:PRK10044 586 ---EAKAAL----SANVNVTgsyTY------------TDAEYTTDTtykgntpaqvPKHMASlwADYTFFDGPLSgltLG 646
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 780535845 676 LRGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGQVGvLQGLKLSLNVTNLTDKRYAS 733
Cdd:PRK10044 647 TGGRYTGSSYGDPANSFKVGSYTVVDALVKYDLARFG-MAGSSVALNVNNLFDREYVA 703
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CirA |
COG1629 |
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism]; |
39-743 |
2.68e-74 |
|
Outer membrane receptor protein, Fe transport [Inorganic ion transport and metabolism];
Pssm-ID: 441236 [Multi-domain] Cd Length: 644 Bit Score: 253.98 E-value: 2.68e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 39 LDAVSVIGQGE-------TRQVQRITQQDIAVLPpGTSIQKLLNRMPGVNVQSNDAfganeESQTISLRGFNG--TRLGY 109
Cdd:COG1629 1 LEEVVVTATRTdeslqdvPGSVSVISREQLEDQP-ATDLGDLLRRVPGVSVTSAGG-----GAGQISIRGFGGggNRVLV 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 110 TLDGLPLGDNAYGNYNglniSRALIAENFGGVELASGIGALgTASTSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRT 189
Cdd:COG1629 75 LVDGVPLNDPSGGDGG----LSYIDPEDIERVEVLRGPSSA-LYGSGALGGVINIVTKKPKDGKGGEVSASYGSYGTYRA 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 190 FLRVDTGDyNGFSAYVSGINAEADMWTRPeSPTTTRQFNAKGVYQF-DGGKLTAFADTSRTSQADYAYLSKSGMARGlgw 268
Cdd:COG1629 150 SLSLSGGN-GKLAYRLSASYRDSDGYRDN-SDSDRYNLRAKLGYQLgDDTRLTLSASYSDSDQDSPGYLTLAALRPR--- 224
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 269 dwnlyapdwnralaaaycapatrnaarcgfsGGVDNIDDAYYQSRALRDDDLFYVAGDFQP-NDAISLHTQVYHHENKGQ 347
Cdd:COG1629 225 -------------------------------GAMDDGTNPYSNDTDDNTRDRYSLSLEYEHlGDGLKLSASAYYRYDDTD 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 348 GHWWSPGQASNPGTpealpisIRSTNYWINRTGGIASLGWEL---GPHHLEAGLWYERNHHDVERNFYWITGPVSddkfl 424
Cdd:COG1629 274 LDSDFTPTPADGGT-------LEQTDFDNRTYGLELRLTYDLgfgGKHTLLVGLDYQRQDLDGSGYPLDLGSGSL----- 341
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 425 qNPNRRLFSQNYVITTRQFYVQGNFKFLDqRLSLDLGIKSPSTEMTARETPGVAVEAPVAtgslKASESVLPQIGLGYRL 504
Cdd:COG1629 342 -PTLTSGADDDGTTTSLALYAQDTYKLTD-KLTLTAGLRYDYVSYDVDDTVTGTDSASGS----RSYSAFSPSLGLTYQL 415
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 505 ADGQEVFASYAENIAAFQGGGAGGPLLVTQASFDASvgaLEPEKSRTLEAGYRV--VRDRFEASLVGYDVTFDNRLLSln 582
Cdd:COG1629 416 SPNLSLYASYSRGFRAPTFGELYANGTDPYSVGNPD---LKPETSTNYELGLRYrlLDGRLSLSLALFYSDVDNEILS-- 490
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 583 pcasIQQGTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNyvqNGVVIPTAGKYTVDTPKRMFA 662
Cdd:COG1629 491 ----VPLPNDSGFSTYYTNAGKARSYGVELELSYQLTPGLSLNASYSYTDAKFDDD---TDGSADLDGNRLPGVPPLTAN 563
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 663 SELAFN-SGPWNLNLRGKYTGQRYYTYTNDQGF-GGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYASNLTAFAN 740
Cdd:COG1629 564 LGLTYEfPGGWSLGLGVRYVGDRYLDDANTQGApGGYTLVDLGAGYRFG-----DNLTLSLGVDNLFDKKYATSLSVRAS 638
|
...
gi 780535845 741 TDP 743
Cdd:COG1629 639 NVR 641
|
|
| FecA |
COG4772 |
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism]; |
29-766 |
1.36e-68 |
|
Outer membrane receptor for Fe3+-dicitrate [Inorganic ion transport and metabolism];
Pssm-ID: 443804 [Multi-domain] Cd Length: 681 Bit Score: 239.06 E-value: 1.36e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 29 SADTGATVQQLDAVSVIGQGETRQ--------VQRITQQDIAVLPPgTSIQKLLNRMPGVNVQSNDAFGaneESQTISLR 100
Cdd:COG4772 13 AAAAAEAATTLETVVVTGSRAAEArlkdvpgsVSVVDREELENQAA-TSLREVLRRVPGVNVQEEDGFG---LRPNIGIR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 101 GFNGTRL-GYTL--DGLPLGDNAYGnYNGLNISRALiaENFGGVELASGIGALgTASTSNLGGTIQYYSADPSSVFGGQV 177
Cdd:COG4772 89 GLGPRRSrGITLleDGIPIAPAPYG-DPAAYYFPDL--ERMERIEVLRGAAAL-RYGPQTVGGAINFVTRTIPTAFGGEL 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 178 SQTVGSDANRRTFLRVDtGDYNGFSAYVSGINAEADMWtRPESPTTTRQFNAKGVYQF-DGGKLTAFADTSRTSQADYAY 256
Cdd:COG4772 165 RVTGGSFGYRRTHASVG-GTVGNFGYLVEYSRKRGDGF-RDNSGFDINDFNAKLGYRLsDRQELTLKFQYYDEDANTPGG 242
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 257 LSKSgmarglgwdwnLYAPDWNRalaaaycapatRNAARcgfsggvdnidDAYYQSRalrddDLFYVAGDFQPNDAISLH 336
Cdd:COG4772 243 LTDA-----------QFDADPRQ-----------SYRPA-----------DQFDTRR-----TQLSLRYEHQLSDNTTLT 284
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 337 TQVYHHENKGQghWWSPGQASNPGTPeALPISIRSTNYWinrTGGI---ASLGWELG--PHHLEAGLWYernHHDVERNF 411
Cdd:COG4772 285 TTAYYNDFSRN--WYIRQNTADPNTP-GLGLRGNPRGYR---SYGIeprLTHRFELGgvPHTLEVGLRY---HREEEDRK 355
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 412 YWITGPVSDDKFLQNPNRRLFSQNYVittrQFYVQGNFKFLDqRLSLDLGIKSPSTEMTARETPGVAVeAPVATGSLKAS 491
Cdd:COG4772 356 QYVNTYGQGRSGAGLRRDRRFSADAL----AAYAQNRFELTG-RLTLTPGLRYEHIRRDRTDRYSTRT-GGDDSGSNSYS 429
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 492 EsVLPQIGLGYRLADGQEVFASYAENIaafqgggagGPLLVTQASF-DASVGALEPEKSRTLEAGYRV-VRDRFEASLVG 569
Cdd:COG4772 430 E-FLPGLGLLYQLTDNLQLYANVSRGF---------EPPTFGDLAYgNGGNPDLKPEKSWNYELGTRGrIGNGLSAEVAL 499
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 570 YDVTFDNRLLSLNpcasiqqgTTPACTTRFFNVGSVSSRGGELTVIWKP----TSYLQWYNSASINRSTYDDNYVQNgvv 645
Cdd:COG4772 500 FYIDYDNELGSCS--------AAGGDRSTFTNAGETRHQGLELALDYDLlkggGLGLPLFAAYTYTDAEFTSDFGPV--- 568
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 646 ipTAGKYTVDTPKRMFASELAFNSGPWNLNLRGKYTGQRYYTYTNDQGFG------GYTSFDAGGGYDFGqvgvlQGLKL 719
Cdd:COG4772 569 --FAGNRLPYVPRHQLTAGLGYEHGGWTANLNGRYVSEQFTDAANTVADGsfgkipSYTVLDLSASYDFG-----KNLSL 641
|
730 740 750 760
....*....|....*....|....*....|....*....|....*..
gi 780535845 720 SLNVTNLTDKRYAsnlTAFANTDPNGRQlafhASAPRQVFLTLDAKF 766
Cdd:COG4772 642 FAGVNNLFDKRYI---ASRAPNYAAGIR----PGPPRTVYAGLRLKF 681
|
|
| ligand_gated_channel |
cd01347 |
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) ... |
53-766 |
4.96e-48 |
|
TonB dependent/Ligand-Gated channels are created by a monomeric 22 strand (22,24) anti-parallel beta-barrel. Ligands apparently bind to the large extracellular loops. The N-terminal 150-200 residues form a plug from the periplasmic end of barrel. Energy (proton-motive force) and TonB-dependent conformational alteration of channel (parts of plug, and loops 7 and 8) allow passage of ligand. FepA residues 12-18 form the TonB box, which mediates the interaction with the TonB-containing inner membrane complex. TonB preferentially interacts with ligand-bound receptors. Transport thru the channel may resemble passage thru an air lock. In this model, ligand binding leads to closure of the extracellular end of pore, then a TonB-mediated signal facillitates opening of the interior side of pore, deforming the N-terminal plug and allowing passage of the ligand to the periplasm. Such a mechanism would prevent the free diffusion of small molecules thru the pore.
Pssm-ID: 238657 [Multi-domain] Cd Length: 635 Bit Score: 180.34 E-value: 4.96e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 53 VQRITQQDIAVLPPgTSIQKLLNRMPGVNVQSNDAFGAneesQTISLRGFNGTRLGYTLDGLPLGDNAYGNYNGLNIsra 132
Cdd:cd01347 2 VSVITAEDIEKQPA-TSLADLLRRIPGVSVTRGGGGGG----STISIRGFGPDRTLVLVDGLPLASSNYGRGVDLNT--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 133 LIAENFGGVELASGIGALGTAStSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTF-----LRVDTGDYNGFSAYVSG 207
Cdd:cd01347 74 IPPELIERVEVLKGPSSALYGS-GAIGGVVNIITKRPTDEFGGSVTAGYGSDNSGSSGgggfdVSGALADDGAFGARLYG 152
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 208 INAEADMWTRPESPTTTRQFNAKGVYqfdgGKLTAFADTSRTSQADYAYLSksgmaRGLGWDWNLYAPDWNRALAAAYCA 287
Cdd:cd01347 153 AYRDGDGTIDGDGQADDSDEERYNVA----GKLDWRPDDDTRLTLDAGYQD-----QDADGPGGTLPANGTGSSLGGGPS 223
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 288 PATRNAARcgfsggvdniddayYQSRALRDDDLFYVAGDFQPNDAISLHTQVYHHENKGQGHW---WSPGQASNPGTPEA 364
Cdd:cd01347 224 SNTNGDRD--------------WDYRDRYRKRASLGLEHDLNDTGWTLRANLSYSYTDNDGDPlilNGGNNAAGGDLGRS 289
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 365 LPISIRSTNYWINRTGGIASLGWELGPHHLEAGLWYERNHHDvernfywitgpvsddkflqnpnRRLFSqnyvittrqFY 444
Cdd:cd01347 290 GYSSERDTTQLGFDAGLNAPFGTGPVAHTLTLGVEYRREELD----------------------EKQTA---------LY 338
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 445 VQGNFKFLDqRLSLDLGIKSPSTEMTARETPgvaveAPVATGSLKASEsVLPQIGLGYRLADGQEVFASYAENIAAFQGG 524
Cdd:cd01347 339 AQDTIELTD-DLTLTLGLRYDHYDQDSKDTI-----AGGTTAKKSYSH-WSPSLGLVYKLTDGLSLYASYSQGFRAPSLG 411
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 525 GAGgPLLVTQASFDASVGALEPEKSRTLEAGYRVVRD-RFEASLVGYDVTFDNRLlslnpcASIQQGTTPACTTRFFNVG 603
Cdd:cd01347 412 ELY-GGGSHGGTAAVGNPNLKPEKSKQYELGLKYDPGdGLTLSAALFRIDIKNEI------VSTPTNTGLGLVTVYVNGG 484
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 604 SVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNYVQNGvviptaGKYTVDTPKRMFASELAFNSGP--WNLNLRGKYT 681
Cdd:cd01347 485 KARIRGVELEASYDLTDGLGLTGSYTYTDTEVKRTDGATT------GNRLPGIPKHTANLGLDYELPDegLTAGGGVRYR 558
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 682 GQRYYTYTNDQGF---GGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYasnltaFANTDPNGRQLAFHASAPRQV 758
Cdd:cd01347 559 GKQYADTANGNNTvkvPGYTLVDLSASYQFT-----KNLTLRLGVNNLFDKDY------YTSLSVRGSGLYGYYGPGRTY 627
|
....*...
gi 780535845 759 FLTLDAKF 766
Cdd:cd01347 628 YLSVSYKF 635
|
|
| FhuE |
COG4773 |
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion ... |
41-766 |
2.41e-42 |
|
Outer membrane receptor for ferric coprogen and ferric-rhodotorulic acid [Inorganic ion transport and metabolism];
Pssm-ID: 443805 [Multi-domain] Cd Length: 692 Bit Score: 164.30 E-value: 2.41e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 41 AVSVIGQgetrqvQRITQQDIavlppgTSIQKLLNRMPGVNVQSNDAFGANeesqTISLRGFNGTrlGYTLDGLPLGDNA 120
Cdd:COG4773 68 SVSVVTR------QLIEDQGA------TTLDDALRNVPGVTVSSYDGGGRD----SFSIRGFSID--NYLRDGLPLGGFG 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 121 YGNYNGLNISRaliaenfggVEL---ASGIgalgTASTSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTflrvdTGD 197
Cdd:COG4773 130 GGQPDTANLER---------VEVlkgPAGL----LYGAGSPGGLVNLVTKRPTAEPQGEVSLSAGSWDTYRA-----TAD 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 198 YNG-------FSAYVSGINAEADMWTRPESpttTRQFNAKGVYQFDGG---KLTAFADTSRTSQ-ADYAYLSKSGMARGL 266
Cdd:COG4773 192 VGGplnedgtLRYRLNAAYEDGDSFRDGVD---NRRTLIAPSLDWDLTddtTLTLGAEYQDDDStGDRGFLPLDGTLLDL 268
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 267 GWDWNlYAPDWNRALaaaycapatrnaarcgfsggvdniddayyqsralRDDDLFYVAGDFQPNDAISLHTQVYHHENKG 346
Cdd:COG4773 269 PRSTN-LGEPWDYYD----------------------------------TETTTLFAELEHRFNDDWSLRANARYSDSDR 313
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 347 QGHWWSPGQASNPGTPEALPISIRSTNYWINRTGGI-ASLGWELGP--HHLEAGLWYERNHHDVERNFYW---ITGPVSD 420
Cdd:COG4773 314 DGRSAYAYGAPDAATGTLTRYASARDGDSRSDSLDAnLNGKFETGGleHTLLVGADYSRYDSDSDSATAGtinIYNPVYG 393
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 421 DkfLQNPNRRLFSQNYVITTRQFYVQGNFKFLDqRLSLDLGIKSPSTEMTARETPGvaveapvATGSLKASESVLPQIGL 500
Cdd:COG4773 394 N--LPEPDFDASDTDTTTRQTGLYAQDQISLTD-RLSLLLGGRYDWYETDSTNRLG-------GSTTSYDDSAFTPRAGL 463
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 501 GYRLADGQEVFASYAENiaafqgggaggplLVTQASFDASVGALEPEKSRTLEAG--YRVVRDRFEASLVGYDVTFDNRL 578
Cdd:COG4773 464 VYDLTPGLSLYASYSES-------------FEPQSGADNNGNPLDPETGKQYEAGvkGELFDGRLNATLAVFDITQKNVA 530
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 579 LslnpcasiqqgTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNYVQNgvviptAGKYTVDTPK 658
Cdd:COG4773 531 T-----------TDPDNPNFYVQVGEVRSRGVELELSGELTPGLNLIAGYTYTDAKITKDADAL------EGKRLTNVPR 593
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 659 RMFA--SELAFNSGPWN---LNLRGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYAS 733
Cdd:COG4773 594 HTASlwTTYRFPSGALKglgLGGGVRYVGERYGDAANTFTLPSYTLVDAGARYDLG-----KNWTLQLNVNNLFDKKYYA 668
|
730 740 750
....*....|....*....|....*....|...
gi 780535845 734 NLTAFANTDPNgrqlafhasAPRQVFLTLDAKF 766
Cdd:COG4773 669 SSGSRGYVYYG---------APRNVRLSLSYKF 692
|
|
| Fiu |
COG4774 |
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism]; |
41-766 |
5.74e-41 |
|
Outer membrane receptor for monomeric catechols [Inorganic ion transport and metabolism];
Pssm-ID: 443806 [Multi-domain] Cd Length: 639 Bit Score: 159.66 E-value: 5.74e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 41 AVSVIgqgeTRQVqrITQQDIavlppgTSIQKLLNRMPGVNVQSndafGANEESQTISLRGFNgTRLGYTLDGLPlgDNA 120
Cdd:COG4774 12 SVTVV----TREL--IEDQGA------TSLADALRNVPGVTFGA----GEGGNGDSFSIRGFS-ASGDIYVDGLR--DPG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 121 YGNYNGLNISRaliaenfggVELASGIGAL--GTASTsnlGGTIQYYSADPSSVFGGQVSQTVGSDANRRTflrvdTGDY 198
Cdd:COG4774 73 QYRRDTFNLER---------VEVLKGPASVlyGRGSP---GGVINLVTKRPTDEPFTEVTLTYGSDGQRRA-----TLDV 135
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 199 NG-----FSAYVSGINAEADMWTrpeSPTTTRQFNAKGVYQFDGGkltafADTSRTSQADYAYlSKSGMARGLGWDWNLY 273
Cdd:COG4774 136 NGplgddLAYRLNGMYRDSDSYR---DGVDNDRWGIAPSLTWRLG-----DRTRLTLDYEYQD-DDRTPDYGVPAVANGR 206
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 274 APDWNRalaaaycapaTRNAarcgfsggvdNIDDAYYQSralrDDDLFYVAGDFQPNDAISLHTQVYHHENKGQGHWWSP 353
Cdd:COG4774 207 PVDVDR----------STFY----------GQPDDYSDS----ETDSATLRLEHDFNDNWTLRNALRYSDYDRDYRNTYP 262
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 354 GQASNPGTPEALPISIRSTN-YWINRTGGIASLgwELGP--HHLEAGLWYERNHHDVERNFYWITGPVSD------DKFL 424
Cdd:COG4774 263 TGGNATGTVTRSAYRRDQDNdTLSNQTDLTGKF--DTGGvkHTLLAGVEYSREDSDNARYSGGGTAPTVNlynpvyGAPV 340
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 425 QNPNRRLFSQNYVITTRQFYVQGNFKFLDqRLSLDLGIKSPSTEMTARETPgvaveAPVATGSLKASEsVLPQIGLGYRL 504
Cdd:COG4774 341 TGPTLGGADNDSRTDTTGLYLQDTISLTD-RWSLLAGLRYDRFDTDYTDRT-----TGATTSSYDDSA-FSPRAGLVYKP 413
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 505 ADGQEVFASYAENIAAFQgggaggpllvTQASFDASVGALEPEKSRTLEAG--YRVVRDRFEASLVGYDVTFDNRLLsln 582
Cdd:COG4774 414 TPNLSLYASYSTSFNPGG----------GAPSLSNAGQALDPEKSRQYEVGvkWDLLDGRLSLTAALFRIEKTNVRT--- 480
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 583 pcasiqqgTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNYVQNgvvipTAGKYTVDTPKRMFA 662
Cdd:COG4774 481 --------TDPANPGVYVQTGEQRSRGVELEATGELTPGWSVLAGYTYLDAEITKSANAA-----NVGNRLPNVPRHSAS 547
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 663 --SELAFNSGPWNLNLRGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYasnltaFAN 740
Cdd:COG4774 548 lwTTYDLPLPGLTLGGGVRYVGSRYADAANTVKLPSYTRFDAGASYRLN-----KNLTLRLNVNNLTDKRY------YAS 616
|
730 740
....*....|....*....|....*.
gi 780535845 741 TDPNGRqlaFHASAPRQVFLTLDAKF 766
Cdd:COG4774 617 AYGSGY---VTPGAPRTVLLSASYRF 639
|
|
| FepA |
COG4771 |
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and ... |
26-710 |
3.06e-33 |
|
Outer membrane receptor for ferrienterochelin and colicins [Inorganic ion transport and metabolism];
Pssm-ID: 443803 [Multi-domain] Cd Length: 612 Bit Score: 136.14 E-value: 3.06e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 26 LEVSADTGATVQQLDAVSVIGQGETRQVQR-------ITQQDIAVLPPgTSIQKLLNRMPGVNVQSNDAFGANeesQTIS 98
Cdd:COG4771 14 AQAADALAEDATELEEVVVTATRTEQSLSDapasvsvITAEEIEKLGA-TDLADALRLLPGVSVTRSGGRGGS---SGIS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 99 LRGFNGTRLGYTLDGLPLGDNAYGNYNGLN-ISRALIAEnfggVELASGIGAlgTASTSN-LGGTIQYYSADPSSVFGGQ 176
Cdd:COG4771 90 IRGLGGDRVLVLIDGVPVNNPALGGGGDLSyIPPDDIER----IEVIRGPAS--ALYGSDaIGGVINIITKKPTDELEGS 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 177 VSQTVGSDANRRTFLRVDTGD-YNGFSAYVSGINAEADMWT-------RPESPTTTRQFNAKGVYQF-DGGKLTAFADTS 247
Cdd:COG4771 164 VSLGYGSNGNGTYSGSLSLGGpGDKLSFLLSGSYRDRDGYLdyrnggfVGNSGYERYNLNAKLGYRLsDNHRLSLSGGYS 243
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 248 RtsqadyaylsksgmarglgwdwnlyapdwnralaaaycapatRNAARCGFSGGVDNIDDAYYQSRALRDDDLFYvAGDF 327
Cdd:COG4771 244 R------------------------------------------QDRDGGPPTLGDTEISSDNAGDRDTTTDRGNY-SLRY 280
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 328 QPNDAISLHTQVYHHENKGQGHWWSPGQASNPGTPealpisirstnYWINRTGGIASLGWELG-PHHLEAGLWYERNHHD 406
Cdd:COG4771 281 NGDLGDNLDLSLYYSRTDRDSTNGSLGGSTGSFSD-----------SDDTTYGLELDLTYPLGgNHTLTLGAEYRYDDLD 349
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 407 vernfywitgpvsDDKFLQNPNRRLFSQNyvittrqFYVQGNFKFLDqRLSLdlgikspstemtareTPGVAVEAPVATG 486
Cdd:COG4771 350 -------------SSSFLGGADASRDTYG-------LFAQDEWKLTD-KLTL---------------TAGLRYDYYSTFG 393
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 487 SlKASESVLPQIGLGYRLADGQEVFASYAE-----NIAAFQGGGAGGPLLVTQASFDasvgaLEPEKSRTLEAG--YRVV 559
Cdd:COG4771 394 A-SNYTAFSPRLGLRYDLSDNLTLRASYGRgfrapSLAELYGSGTGTPGRYVLGNPD-----LKPETSDNYELGleYRLG 467
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 560 RDRFEASLVGYDVTFDNRLlslnpcASIQQGTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRSTYDDNy 639
Cdd:COG4771 468 NGGLSLSLTGFYTDIKDLI------VLVPVGPGPGDVLQYENVGKARTYGLELELKYRLGKGLTLTASYTYLDSKIDDG- 540
|
650 660 670 680 690 700 710
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 780535845 640 vqngvvipTAGKYTVDTPKRMFASELAFNSGP-WNLNLRGKYTGQRYYTY---TNDQGFGGYTSFDAGGGYDFGQ 710
Cdd:COG4771 541 --------DTGEPLPNVPPHKANLGLDYRLPKwWLLLLLTRYYGGRYVTPpsgRLEGYTPGYTLLDLRASYKLTK 607
|
|
| TonB_dep_Rec |
pfam00593 |
TonB dependent receptor; This model now only covers the conserved part of the barrel structure. |
299-765 |
1.51e-29 |
|
TonB dependent receptor; This model now only covers the conserved part of the barrel structure.
Pssm-ID: 395474 [Multi-domain] Cd Length: 475 Bit Score: 122.96 E-value: 1.51e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 299 SGGVDNIDDAYYQSRALRDDDLFYVAGDFQPNDAISLHTQVYHHENKGQGHwwspGQASNPGTPEALPISIRSTNYWINR 378
Cdd:pfam00593 41 GGYLGDRPLYYGRDYSDTDRKRLSLGYDYDLGDGLSWLSTLRLGLRYSSLD----GDYTSNSSGLSGAGDYLSDDRLYGL 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 379 TGGIASLGWELGphhLEAGLWYERNHHDVERNFYWITGPVSDDKFLQNPNRRlFSQNYVITTRQFYVQGNFKFLDqRLSL 458
Cdd:pfam00593 117 YGLDGDLELSLD---LSHDLLLGVELRTAGLDYRRLDDDAYDPYDPANPSSS-SYSDTTTDSYGLYLQDNIKLTD-RLTL 191
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 459 DLGIKSPSTEMTARETPGVAveapvaTGSLKASESVLPQIGLGYRLADGQEVFASYAENIAA-FQGGGAGGPLLVTQASF 537
Cdd:pfam00593 192 TLGLRYDHYSTDGDDGNGGG------DNFSRSYSAFSPRLGLVYKPTDNLSLYASYSRGFRApSLGELYGSGSGGGGGAV 265
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 538 DASVGALEPEKSRTLEAGYRVVRDRFEASLVGYDVTFDNRLLSLNpcasiQQGTTPACTTRFFNVGSVSSRGGELTViwk 617
Cdd:pfam00593 266 AGGNPDLKPETSDNYELGLKYDDGRLSLSLALFYIDIKNLITSDP-----DGPGLGGTVYTYTNVGKARIRGVELEL--- 337
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 618 ptSYLQWYNSASINRSTYDDNYVQNGVVipTAGKYTVDTPKRMF--ASELAFNSGPWNLNLRGKYTGQ---RYYTYTNDQ 692
Cdd:pfam00593 338 --SGRLWGLGLSGGGYTYTDADDDADAD--DTGNPLPNVPRHTAnlGLTYDFPLGGWGARLGARYVGSgerRYGDAANTF 413
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 780535845 693 GFGGYTSFDAGGGYDFGqvgvlQGLKLSLNVTNLTDKRYASnltafaNTDPNGRQLAFHASAPRQVFLTLDAK 765
Cdd:pfam00593 414 KTPGYTLVDLSAGYRLN-----KNLTLRLGVNNLFDKYYKR------YYSSGGGNLGGYPGPGRTFYLGLSYK 475
|
|
| TonB-siderophor |
TIGR01783 |
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of ... |
53-766 |
7.02e-28 |
|
TonB-dependent siderophore receptor; This subfamily model encompasses a wide variety of TonB-dependent outer membrane siderophore receptors. It has no overlap with TonB receptors known to transport other substances, but is likely incomplete due to lack of characterizations. It is likely that genuine siderophore receptors will be identified which score below the noise cutoff to this model at which point the model should be updated. [Transport and binding proteins, Cations and iron carrying compounds, Transport and binding proteins, Porins]
Pssm-ID: 273805 [Multi-domain] Cd Length: 651 Bit Score: 119.82 E-value: 7.02e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 53 VQRITQQDIAvLPPGTSIQKLLNRMPGVNVQSNdafGANEESQTISLRGFNGT--RLGYTLDGLPLGdnaygnyngLNIS 130
Cdd:TIGR01783 6 VSVITRQELE-DQQAGSLSEALQRVPGVVVGGS---GGTTQFGNITIRGFGLEvdIDNVYLDGVPLL---------SRGN 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 131 RALIA-ENFGGVELASGIGALgTASTSNLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTFLRVD--TGDYNGFSAYVSG 207
Cdd:TIGR01783 73 LAIVDpAMVERVEVLRGPASL-LYGGSAPGGVINIVTKRPQDEPKGSVTFGAGTRSGYRTAFDLGgpLGADGTFRGRLNG 151
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 208 INAEADMWtrpesptttRQFNAKGVYqFDGGKLTAFADTSRTSQADYAYLSksGMARGLGWDWNLYAPDWNRALAAAYCA 287
Cdd:TIGR01783 152 ARQDGDSF---------YDGAGEETR-LGATATDWQLDDRTLLRLGAYYQK--ERDRGGYGGLPASGGTSGRDLSSDRYL 219
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 288 PATRNAarcgfsggvdNIDDAYYQSRALRDDDLF------YVAGDFQPNDAISlhtqvyhhENKGQGHWWSPGQASNPgt 361
Cdd:TIGR01783 220 GTSSNR----------NYDDREYLSYGLSLEYQFndvwtgKQNLRYSYFDTDS--------NQVQASGYSSDGGLFGR-- 279
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 362 pealpisiRSTNYWINRTGGIASLG----WELGP--HHLEAGLWYERNHHDVERNFYWITGPVsDDKFLQNPNRRLFSQN 435
Cdd:TIGR01783 280 --------SLTVVNVKQDRVQIDAGldgeFETGPieHDLLLGVSYGQRTTNRFNNTGYPSDNI-YSLTATSSARTDIGDS 350
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 436 YVI--TTRQFYVQGNF----KFLDQRLSLDLGIKSPSTEMTAreTPGVAVEapvaTGSLKASEsVLPQIGLGYRLADGQE 509
Cdd:TIGR01783 351 PKDraLSSTTKALNGValqrILLADKWTLTLGGRYDSVDVKS--NNGVAGS----TGKRDDSQ-FTPSLGVAYKPTDDWS 423
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 510 VFASYAENIAafqgggaggPLLVTQASFDASVGALEPEKSRTLEAGYRVVR-DRFEASLVGYDVTFDNRLLSLnpcasiq 588
Cdd:TIGR01783 424 LYASYAESFK---------PGGYYPKGAGNSGDILEPEKGKNYELGVRYDLgDSLLATAALFRITKDNQLVQD------- 487
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 589 qgttPACTTRFFNVGSVSSRGGELTVIWKPTSYLQWYNSASINRS-TYDDNYVQNGvviptaGKYTVDTPKRMFASELAF 667
Cdd:TIGR01783 488 ----PVNGTFSVNAGKTRNRGVELEARGYLTPGLSLSAGYTYTDAeFTEDTNGDTQ------GNTVPFVPKHTASLWASY 557
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 668 NSGPWNLNL----RGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGQVgvlQGLKLSLNVTNLTDKRY---ASNLTAFAN 740
Cdd:TIGR01783 558 APPVGDNGLtlggGVQYTGKAYVDGGNTGKVPSYTVVDLSVRYDLTKK---KNLTLALNVNNLFDRDYytsGYRWGPSAY 634
|
730 740
....*....|....*....|....*.
gi 780535845 741 TDPNgrqlafhasAPRQVFLTLDAKF 766
Cdd:TIGR01783 635 IYPG---------APRTVGLSVSYDF 651
|
|
| BtuB |
COG4206 |
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism]; |
42-311 |
3.71e-16 |
|
Outer membrane cobalamin receptor protein BtuB [Coenzyme transport and metabolism];
Pssm-ID: 443355 [Multi-domain] Cd Length: 276 Bit Score: 79.53 E-value: 3.71e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 42 VSVIGQGETRQ-------VQRITQQDIAVLPPgTSIQKLLNRMPGVNVQSNDAFGANeesQTISLRGFNGTRLGYTLDGL 114
Cdd:COG4206 1 VVVTATRLEQSksdltgsVTVIDAEELERSGA-TSLADALRRVPGVQVSSSGGPGSA---ASISIRGLGSNQTLVLIDGV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 115 PLGDNAYGNYNGLNISRALIAEnfggVELASGIGAL--GTAStsnLGGTIQYYSADPSSVFGGQVSQTVGSDANRRTFLR 192
Cdd:COG4206 77 PLNDPSLGGVDLSLIPPDDIER----IEVLKGAASAlyGSDA---IGGVINITTKKGKKGFKGSVSASYGSFGTRRLSAS 149
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 193 V-DTGDYNGFSAYVSGINAE----ADMWTRPESPTTTRQFNAKGVYQF-DGGKLTAFA-DTSRTSQADYAYLSKSGMARG 265
Cdd:COG4206 150 LsGGAGKFSYSLSASYRRSDgyryNDPDLRNNDGYENTSLNARLGYKLgDNGSLSLSGgYSDSERGYPGAVGSDRNLRLS 229
|
250 260 270 280
....*....|....*....|....*....|....*....|....*.
gi 780535845 266 LGWDWNLYAPDWNRALAAAYCAPATRNAARCGFSGGVDNIDDAYYQ 311
Cdd:COG4206 230 LSLEYKLSDGWSLLLLAYYYYDRDYEDGGGDSAGTSNTDGARAGLS 275
|
|
| Plug |
pfam07715 |
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently ... |
53-134 |
1.56e-11 |
|
TonB-dependent Receptor Plug Domain; The Plug domain has been shown to be an independently folding subunit of the TonB-dependent receptors. It acts as the channel gate, blocking the pore until the channel is bound by ligand. At this point it under goes conformational changes opens the channel.
Pssm-ID: 462243 [Multi-domain] Cd Length: 107 Bit Score: 61.52 E-value: 1.56e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 53 VQRITQQDIAVLPpGTSIQKLLNRMPGVNVQSndafGANEESQTISLRGFNGTRLGYTLDGLPLGDNAYGNYNGLNISRA 132
Cdd:pfam07715 9 VSVVTAEDIEDQG-ATNLADALRGVPGVSVSS----GGGGGGSSISIRGFGSNRVLVLVDGVPLNSGGGGSVDLNSIDPE 83
|
..
gi 780535845 133 LI 134
Cdd:pfam07715 84 DI 85
|
|
| OMP_b-brl_3 |
pfam14905 |
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB ... |
544-742 |
3.51e-07 |
|
Outer membrane protein beta-barrel family; This family includes proteins annotated as TonB dependent receptors. But it is also likely to contain other membrane beta barrel proteins of other functions.
Pssm-ID: 434300 [Multi-domain] Cd Length: 407 Bit Score: 53.43 E-value: 3.51e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 544 LEPEKSRTLEAGYrVVRDRFEASLvGYDVTFDNRLLSlnpcaSIQQGTTPACTTRFFNVGSVSSRGGELTVIWKPTSYLQ 623
Cdd:pfam14905 212 LKPEYTNSFELGY-TYKWKLSLSL-SYRYTNDVIQQT-----FITDDNDNVTYTTYENLGKSNSYGLELSASFNPTKWWS 284
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 624 WYNSASINRSTYDDNYVQNGvviptagkyTVDTPKRMFASELAFN-SGPWNLNLRGKYTGQRYYTYTNDQGFGgytSFDA 702
Cdd:pfam14905 285 LNGNLNGYYNKYKIDGSLNS---------DFSNFGFNWNLNNTFTlPKGWSLQLNGNYRSPRVTGQGKIKPFY---SLDL 352
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 780535845 703 GGGYDFgqvgvLQG-LKLSLNVTNLTDKRYASNLTAFANTD 742
Cdd:pfam14905 353 GLSKSF-----LKKkLTLSLNVNDIFNTRKFRSTTNYDNGF 388
|
|
| PRK10044 |
PRK10044 |
ferrichrome outer membrane transporter; Provisional |
538-733 |
2.07e-06 |
|
ferrichrome outer membrane transporter; Provisional
Pssm-ID: 236643 [Multi-domain] Cd Length: 727 Bit Score: 51.30 E-value: 2.07e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 538 DASVGALEPEKSRTLEAGYRVV-RDR-FEASLVGYDVTFDNRLLS--LNPCASIQQGttpacttrffnvgSVSSRGGELt 613
Cdd:PRK10044 520 GKDGNIFAPSKGKQYEAGVKYVpKDRpIVVTGAVYQLTKTNNLTAdpENSFFSVQGG-------------EIRARGVEL- 585
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 614 viwKPTSYLqwynSASINRS---TYddnyvqngvvipTAGKYTVDT----------PKRMFA--SELAFNSGPWN---LN 675
Cdd:PRK10044 586 ---EAKAAL----SANVNVTgsyTY------------TDAEYTTDTtykgntpaqvPKHMASlwADYTFFDGPLSgltLG 646
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 780535845 676 LRGKYTGQRYYTYTNDQGFGGYTSFDAGGGYDFGQVGvLQGLKLSLNVTNLTDKRYAS 733
Cdd:PRK10044 647 TGGRYTGSSYGDPANSFKVGSYTVVDALVKYDLARFG-MAGSSVALNVNNLFDREYVA 703
|
|
| PRK13524 |
PRK13524 |
FepA family TonB-dependent siderophore receptor; |
27-101 |
4.94e-05 |
|
FepA family TonB-dependent siderophore receptor;
Pssm-ID: 237410 [Multi-domain] Cd Length: 744 Bit Score: 46.95 E-value: 4.94e-05
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 780535845 27 EVSADTGAtvQQLDAVSVIGQGETRQ---VQRITQQDIAVLPPGTSIQKLLNRMPGVNVQSNDAFGANEESQTISLRG 101
Cdd:PRK13524 28 AKTDDTPA--SHEDTIVVTAAEQNLQapgVSTITAEDIRKRPPANDVSEIIRTMPGVNLTGNSTSGQRGNNRQIDIRG 103
|
|
| PRK13528 |
PRK13528 |
outer membrane receptor FepA; Provisional |
26-101 |
6.15e-04 |
|
outer membrane receptor FepA; Provisional
Pssm-ID: 237413 [Multi-domain] Cd Length: 727 Bit Score: 43.21 E-value: 6.15e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 780535845 26 LEVSADTGATVQQLDAVSVIGQGET--RQ---VQRITQQDIAVLPPGTSIQKLLNRMPGVNVQSNDAFGANEESQTISLR 100
Cdd:PRK13528 21 SPVSAAESSDDDNGETMVVEATAEQelKQqpgVSIITAEDIKKRPPVNDLSDIIRKMPGVNLTGNSASGTRGNNRQIDIR 100
|
.
gi 780535845 101 G 101
Cdd:PRK13528 101 G 101
|
|
| |
