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Conserved domains on  [gi|77798169|ref|NP_001030013|]
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inositol 1,4,5-trisphosphate receptor-interacting protein-like 2 precursor [Homo sapiens]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mab-21_C super family cl48430
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-453 8.32e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam20266:

Pssm-ID: 466416  Cd Length: 102  Bit Score: 53.01  E-value: 8.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   374 KCLQLLKALRDLGARGLDsaaatQWGRILSSYVLKTVLLAVLLRKGAPGQgWDEEHLGRCLEELVQFLRDClLRRHTLFH 453
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVK-----TELSKICSYHLKTLFLWECEKHPDDSD-WDKENLSDRFLGLLEELHKC-LRNGKLPH 76
Mab-21 super family cl03978
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 163-266 2.08e-03

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


The actual alignment was detected with superfamily member pfam03281:

Pssm-ID: 460873  Cd Length: 191  Bit Score: 39.33  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   163 YEQHKIRRPDSFDVLVPLRLPPLVALEprsLGEEPALAPAFRGCFLCALKAPPSpsgasgghWLRDCKPFadafcVDVRG 242
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMNDLII---VMGVPGYVVLKLTRWRYYLHNPVG--------RPESLSQW-----LEFTA 65

                          90       100
                  ....*....|....*....|....
gi 77798169   243 RRHLSATLVLRWFQSHLQRSLATV 266
Cdd:pfam03281  66 EGYLSAAKVLSRFQSLVEKALNTV 89
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-453 8.32e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 53.01  E-value: 8.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   374 KCLQLLKALRDLGARGLDsaaatQWGRILSSYVLKTVLLAVLLRKGAPGQgWDEEHLGRCLEELVQFLRDClLRRHTLFH 453
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVK-----TELSKICSYHLKTLFLWECEKHPDDSD-WDKENLSDRFLGLLEELHKC-LRNGKLPH 76
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 163-266 2.08e-03

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 39.33  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   163 YEQHKIRRPDSFDVLVPLRLPPLVALEprsLGEEPALAPAFRGCFLCALKAPPSpsgasgghWLRDCKPFadafcVDVRG 242
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMNDLII---VMGVPGYVVLKLTRWRYYLHNPVG--------RPESLSQW-----LEFTA 65

                          90       100
                  ....*....|....*....|....
gi 77798169   243 RRHLSATLVLRWFQSHLQRSLATV 266
Cdd:pfam03281  66 EGYLSAAKVLSRFQSLVEKALNTV 89
 
Name Accession Description Interval E-value
Mab-21_C pfam20266
Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In ...
 374-453 8.32e-09

Mab-21 protein HhH/H2TH-like domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 466416  Cd Length: 102  Bit Score: 53.01  E-value: 8.32e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   374 KCLQLLKALRDLGARGLDsaaatQWGRILSSYVLKTVLLAVLLRKGAPGQgWDEEHLGRCLEELVQFLRDClLRRHTLFH 453
Cdd:pfam20266   4 KCLRILKKLKEPGKRDVK-----TELSKICSYHLKTLFLWECEKHPDDSD-WDKENLSDRFLGLLEELHKC-LRNGKLPH 76
Mab-21 pfam03281
Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like ...
 163-266 2.08e-03

Mab-21 protein nucleotidyltransferase domain; This family contains Mab-21 and Mab-21 like proteins. In C. elegans these proteins are required for several aspects of embryonic development.


Pssm-ID: 460873  Cd Length: 191  Bit Score: 39.33  E-value: 2.08e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 77798169   163 YEQHKIRRPDSFDVLVPLRLPPLVALEprsLGEEPALAPAFRGCFLCALKAPPSpsgasgghWLRDCKPFadafcVDVRG 242
Cdd:pfam03281   2 YENLKVLSPDEFDVMLPLRGPMNDLII---VMGVPGYVVLKLTRWRYYLHNPVG--------RPESLSQW-----LEFTA 65

                          90       100
                  ....*....|....*....|....
gi 77798169   243 RRHLSATLVLRWFQSHLQRSLATV 266
Cdd:pfam03281  66 EGYLSAAKVLSRFQSLVEKALNTV 89
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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