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Conserved domains on  [gi|7715736|gb|AAF68161|]
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NADH dehydrogenase subunit 2, partial (mitochondrion) [Grallaria rufula]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 super family cl33352
NADH dehydrogenase subunit 2; Provisional
 1-167 6.77e-58

NADH dehydrogenase subunit 2; Provisional


The actual alignment was detected with superfamily member MTH00112:

Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 183.87  E-value: 6.77e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00112 179 MAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLT 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLWQINKSVNTLTTTLMALTLMLLPL 160
Cdd:MTH00112 259 GFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTTLSTLLLPL 338


                 ....*..
gi 7715736   161 SPMTYTI 167
Cdd:MTH00112 339 SPMILTI 345
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-167 6.77e-58

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 183.87  E-value: 6.77e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00112 179 MAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLT 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLWQINKSVNTLTTTLMALTLMLLPL 160
Cdd:MTH00112 259 GFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTTLSTLLLPL 338


                 ....*..
gi 7715736   161 SPMTYTI 167
Cdd:MTH00112 339 SPMILTI 345
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-120 2.13e-08

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 52.04  E-value: 2.13e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    1 LAFSSISHLGWMTTILIYNPKLTL--LTFYL--YWLMTTAIFLTlnttkILKLSTMMTAWTKI----------PSLTATL 66
Cdd:COG1007 297 LAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAV-----ILLLSRKGGEAEEIedlaglarrsPLLALAM 371

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 7715736   67 MLALLSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAY 120
Cdd:COG1007 372 TIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-119 1.32e-06

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 46.87  E-value: 1.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736      1 LAFSSISHLGWMTTILIYNPKLTL--LTFYL--YWLMTTAIFLTL------NTTKILKLSTMMTAWTKIPSLTATLMLAL 70
Cdd:TIGR01770 297 LAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFGVLsllrsyKDEWIEYISDFAGLFKTNPILAILILIFM 376

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 7715736     71 LSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLA 119
Cdd:TIGR01770 377 FSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-90 5.32e-05

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 41.92  E-value: 5.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736      1 LAFSSISHLGWMTTIL----IYNPKLTLLTFYLYWLMTTAIFL-----TLNTTKILKLSTMMTAWTKIPSLTATLMLALL 71
Cdd:pfam00361 175 LAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAKTMPILALVFLVAML 254

                          90
                  ....*....|....*....
gi 7715736     72 SLAGLPPLTGFLPKWLIIQ 90
Cdd:pfam00361 255 SLAGLPPTAGFLGKFLILA 273
 
Name Accession Description Interval E-value
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-167 6.77e-58

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 183.87  E-value: 6.77e-58
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00112 179 MAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTLNTTLMLTLLSLAGLPPLT 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLWQINKSVNTLTTTLMALTLMLLPL 160
Cdd:MTH00112 259 GFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPKKNTLTATLTTLSTLLLPL 338


                 ....*..
gi 7715736   161 SPMTYTI 167
Cdd:MTH00112 339 SPMILTI 345
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-137 8.68e-47

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 155.35  E-value: 8.68e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00135 178 LAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPALTALTPLILLSLGGLPPLT 257

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLW 137
Cdd:MTH00135 258 GFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPW 314
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-162 1.48e-41

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 141.98  E-value: 1.48e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00070 179 MAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTLTSMMMLTLLSLGGLPPTT 258

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLWQINKSVNTLTTTLMALTLMLLPL 160
Cdd:MTH00070 259 GFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRFKNKTNNLLSLTIILSLMLLPI 338


                 ..
gi 7715736   161 SP 162
Cdd:MTH00070 339 TP 340
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-138 1.91e-35

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 126.11  E-value: 1.91e-35
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00105 179 LAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLMTSLILLTLLSLGGLPPLT 258

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPnSINYMKL-WQ 138
Cdd:MTH00105 259 GFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFP-STNNMKMkWQ 316
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-137 2.55e-29

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 109.67  E-value: 2.55e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00200 179 LAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPILSMLLGLTLLSLGGLPPLT 258

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLW 137
Cdd:MTH00200 259 GFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSW 315
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-144 2.89e-21

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 88.06  E-value: 2.89e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00041 179 LAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPISAFLFILSILSLGGLPPLT 258

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPNSINYMKLWQINKSVN 144
Cdd:MTH00041 259 GFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQHSISLFSWRNSGNIT 322
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-142 3.25e-17

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 76.79  E-value: 3.25e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00160 171 LAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKIKFLLFLNLLSLGGLPPFL 250

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCAtITLPPNSINYMKLWQINKS 142
Cdd:MTH00160 251 GFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSS-LMLNYNKNKWNLKKKKNKF 311
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 1-132 1.26e-14

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 69.81  E-value: 1.26e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00011 175 LAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLSLGGLPPFT 254

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYcATITLPPNSIN 132
Cdd:MTH00011 255 GFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIF-NFMYLSPTFSS 305
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 1-120 1.14e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 67.00  E-value: 1.14e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLSTMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00197 164 LAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSLGGLPPLS 243

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAY 120
Cdd:MTH00197 244 GFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAY 283
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 1-124 2.90e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 66.06  E-value: 2.90e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLLTFYLYWLMTTAIFLTLNTTKILKLStMMTAWTKIPSLTATLMLALLSLAGLPPLT 80
Cdd:MTH00144 172 LAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMK-DLGSLKPSYKTGLSIISLLLSLGGLPPFL 250

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 7715736    81 GFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATI 124
Cdd:MTH00144 251 GFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFL 294
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 1-120 2.13e-08

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 52.04  E-value: 2.13e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    1 LAFSSISHLGWMTTILIYNPKLTL--LTFYL--YWLMTTAIFLTlnttkILKLSTMMTAWTKI----------PSLTATL 66
Cdd:COG1007 297 LAYSSIAHAGYLLLGLAAGTPLGVsaALFYLlaYLFMNLGAFAV-----ILLLSRKGGEAEEIedlaglarrsPLLALAM 371

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 7715736   67 MLALLSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAY 120
Cdd:COG1007 372 TIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
1-118 5.60e-07

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 47.89  E-value: 5.60e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTL--LTFYL--YWLMTTAIFLTL--------NTTKILKLSTMmtAWTKiPSLTATLML 68
Cdd:PRK05777 298 LAYSSIAHAGYLLVGLAAGTAEGYsaVLFYLlaYLFMTLGAFGVIsllrrkggEAESISDFAGL--SKRS-PLLAAVMTI 374

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 7715736    69 ALLSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRL 118
Cdd:PRK05777 375 FMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRV 424
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 1-118 8.39e-07

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 47.45  E-value: 8.39e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    1 LAFSSISHLGWMTT-ILIYNPKLTLLTFYLYW---LMTTAIFLT----LNTTKILKLSTMMTAWTKIPSLTATLMLALLS 72
Cdd:COG0651 300 LAYSSVSQIGYILLgLGLGTPLGLAGALFHLLnhaLAKALLFLAagaiERATGTRDLDKLGGLGKRMPLTAAAFLIGALA 379

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 7715736   73 LAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRL 118
Cdd:COG0651 380 LAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRI 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 1-119 1.32e-06

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 46.87  E-value: 1.32e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736      1 LAFSSISHLGWMTTILIYNPKLTL--LTFYL--YWLMTTAIFLTL------NTTKILKLSTMMTAWTKIPSLTATLMLAL 70
Cdd:TIGR01770 297 LAYSSISHVGYILIGLLAGTLEGIkaVLFYIfiYALMSLGAFGVLsllrsyKDEWIEYISDFAGLFKTNPILAILILIFM 376

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*....
gi 7715736     71 LSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLA 119
Cdd:TIGR01770 377 FSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 1-90 5.32e-05

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 41.92  E-value: 5.32e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736      1 LAFSSISHLGWMTTIL----IYNPKLTLLTFYLYWLMTTAIFL-----TLNTTKILKLSTMMTAWTKIPSLTATLMLALL 71
Cdd:pfam00361 175 LAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLcagsvIYRRVHTRNIRDYGGLAKTMPILALVFLVAML 254

                          90
                  ....*....|....*....
gi 7715736     72 SLAGLPPLTGFLPKWLIIQ 90
Cdd:pfam00361 255 SLAGLPPTAGFLGKFLILA 273
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 1-129 1.27e-03

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 38.32  E-value: 1.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTILIYNPKLTLL--TFYLY---------WLMTTAIFLTLNTTKILKLSTMMTawtKIPSLTATLMLA 69
Cdd:PRK08375 299 LAYSTVSQMGYILLGLALLTPLALAagLLHLLhhalmkgalFLAAGAIEVTYGTRRLSELSGLGR---RMPLTAAAFAVA 375

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    70 LLSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAYCATITLPPN 129
Cdd:PRK08375 376 SLSLIGVPPTSGFVSKWYLVVGAVEAGQWLVLAVLLASSLLALLYFLRIWYRAFFGPPPP 435
PRK08668 PRK08668
NADH dehydrogenase subunit M; Validated
 1-120 1.46e-03

NADH dehydrogenase subunit M; Validated


Pssm-ID: 236332 [Multi-domain]  Cd Length: 610  Bit Score: 38.05  E-value: 1.46e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWmttILIYNPKLTLLTFY--------------LYWLMTTAIFLTLNTTKIlklSTMMTAWTKIPSLTATL 66
Cdd:PRK08668 300 IAYSSVANGGY---ILVGLGLGTSLGFAgglfhvfnhalfkgLFFLIFAAVIYRTGTTKI---SEMGGLIEKMPFTFAMY 373

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....
gi 7715736    67 MLALLSLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRLAY 120
Cdd:PRK08668 374 LVAIISLAGIPPMSGFASKWLIFEALISKGMPITAFMAFFGSIGSFLYVFRPLA 427
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 1-118 1.92e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 37.70  E-value: 1.92e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWMTTIL----IYNPKLTLLTFYLYWLMTTAIF---LTLNTTK--ILKLSTMMTawtKIPSLTATLMLALL 71
Cdd:MTH00196 180 LAYSGIGHMGFVLWGIeigsFESIQASLVYLFIYIIMSICVFsiiLALNVYKnlIIEFSGLSR---RLPILAITLALTFL 256

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 7715736    72 SLAGLPPLTGFLPKWLIIQELTKQEMTPAATIIALLSLLGLFFYLRL 118
Cdd:MTH00196 257 SIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRI 303
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 1-120 3.50e-03

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 37.05  E-value: 3.50e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736    1 LAFSSISHLGWMTTILiynpKLTLLTFYLYWLMTTAIF------------LTLNTTKILKLSTMmtaWTKIPSLTATLML 68
Cdd:COG1009 303 LAYSTVSQLGYMFLAL----GVGAYVAALFHLLTHAFFkallflgagsviHATGTRDIRKMGGL---RKKMPITAITFLI 375

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....
gi 7715736   69 ALLSLAGLPPLTGFLPKWLIIQE-LTKQEMTPAATIIALL-SLLGLFFYLRLAY 120
Cdd:COG1009 376 GALSLAGIPPFAGFFSKEAILEAaLEAGGLGPLLLAVALLgAFLTAFYSFRLFF 429
PRK12650 PRK12650
DUF4040 family protein;
1-126 6.96e-03

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 36.17  E-value: 6.96e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7715736     1 LAFSSISHLGWM-TTILIYNP-KLT--LLTFYLYWLMTTAIFLTLN-------TTKILKLSTMmtaWTKIPSLTATLMLA 69
Cdd:PRK12650 300 TAYSTVSQLGWIvATIGVGTPfALTaaVVHTLAHALFKSSLFMLIGvvdhqagTRDIRRLGSL---WRRMPFTFVSVTIA 376

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 7715736    70 LLSLAGLPPLTGFLPKWLIIQELTKQEMtPAATIIALLSLLGLFFYLRLAYCATITL 126
Cdd:PRK12650 377 ALSMAAVPPLFGFVSKEGMLTAFLEAPG-GNAGVVLLLVGAALGAVFTFAYSARLVL 432
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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