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Conserved domains on  [gi|767950614|ref|XP_011542724|]
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N-acetyltransferase ESCO2 isoform X2 [Homo sapiens]

Protein Classification

ECO family N-acetyltransferase( domain architecture ID 10620681)

ECO family N-acetyltransferase contains a C2H2 zinc finger, is required for the establishment of sister chromatid cohesion, and may acetylate components of the cohesin complex

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
529-591 1.80e-24

ESCO1/2 acetyl-transferase;


:

Pssm-ID: 464015  Cd Length: 69  Bit Score: 96.78  E-value: 1.80e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767950614  529 EPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDDCRRLNRYQET 591
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGT 63
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
374-413 4.47e-16

zinc-finger of acetyl-transferase ESCO;


:

Pssm-ID: 464013  Cd Length: 40  Bit Score: 71.88  E-value: 4.47e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 767950614  374 QLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHR 413
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
529-591 1.80e-24

ESCO1/2 acetyl-transferase;


Pssm-ID: 464015  Cd Length: 69  Bit Score: 96.78  E-value: 1.80e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767950614  529 EPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDDCRRLNRYQET 591
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGT 63
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
374-413 4.47e-16

zinc-finger of acetyl-transferase ESCO;


Pssm-ID: 464013  Cd Length: 40  Bit Score: 71.88  E-value: 4.47e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 767950614  374 QLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHR 413
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Name Accession Description Interval E-value
Acetyltransf_13 pfam13880
ESCO1/2 acetyl-transferase;
529-591 1.80e-24

ESCO1/2 acetyl-transferase;


Pssm-ID: 464015  Cd Length: 69  Bit Score: 96.78  E-value: 1.80e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 767950614  529 EPAVCGISRIWVFRLKRRKRIARRLVDTLRNCFMFGCFLSTDEIAFSDPTPDDCRRLNRYQET 591
Cdd:pfam13880   1 VPAKCGISRIWVSPSHRRKGIATRLLDAARSNFIYGYILEKDEIAFSQPTESGKAFARKYFGT 63
zf-C2H2_3 pfam13878
zinc-finger of acetyl-transferase ESCO;
374-413 4.47e-16

zinc-finger of acetyl-transferase ESCO;


Pssm-ID: 464013  Cd Length: 40  Bit Score: 71.88  E-value: 4.47e-16
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|
gi 767950614  374 QLIIDAGQKHFGATVCKSCGMIYTASNPEDEMQHVQHHHR 413
Cdd:pfam13878   1 QLILDLGQKSFGATQCKECGMVYNPGSPEDEKLHKKYHAR 40
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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