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Conserved domains on  [gi|767201008|gb|AJS79652|]
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Pse1p [Saccharomyces cerevisiae YJM1242]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Importin_rep_6 pfam18829
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 766-868 1.40e-24

Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.


:

Pssm-ID: 465881  Cd Length: 110  Bit Score: 99.48  E-value: 1.40e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   766 ITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDRHGD--GDEYNENIDEEEDFTDED---LLDEINK 840
Cdd:pfam18829    1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEErkDDDYDEEVEEDLEEEEETdeeLLSEINK 80

                           90       100
                   ....*....|....*....|....*...
gi 767201008   841 SIAAVLKTTNGHYLKNLENIWSMINTFL 868
Cdd:pfam18829   81 AIHAIFKTHKTAFLPYFEQLLPTVVAFL 108
Importin_rep_4 super family cl40101
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 274-365 1.84e-23

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.


The actual alignment was detected with superfamily member pfam18808:

Pssm-ID: 408579  Cd Length: 90  Bit Score: 95.61  E-value: 1.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   274 NKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVsiddDDAAEW-IESDDTDDEEEVTYDHARQAL 352
Cdd:pfam18808    1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEV----DDAEDWyTSDDLDDDDNEDNYVFGEQAL 76

                           90
                   ....*....|...
gi 767201008   353 DRVALKLGGEYLA 365
Cdd:pfam18808   77 DRLACRLGGKALL 89
Importin_rep_5 pfam18816
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 1001-1054 1.98e-16

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.


:

Pssm-ID: 465877  Cd Length: 52  Bit Score: 74.05  E-value: 1.98e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767201008  1001 DKEAASFNYQFLSQLIENNSPIVCaqSNISAVVDSVIQALNERSLTEREGQTVI 1054
Cdd:pfam18816    1 DEEAAPFAYRFLAELIEQNHPAVT--SQIPKVVDSVVQALEHKSLSGKTAERVV 52
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 381-435 1.00e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


:

Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.12  E-value: 1.00e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   381 WRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQI 435
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 403-475 2.49e-03

HEAT repeats; This family includes multiple HEAT repeats.


:

Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.09  E-value: 2.49e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   403 IGEI--PKILDMVIPLINDPHPRVQYGCCNVLGQISTdfspfiqrtahDRILPALISKLTSECTSRVQTHAAAAL 475
Cdd:pfam13646   24 LGRIgdPEAVPALLELLKDEDPAVRRAAAEALGKIGD-----------PEALPALLELLRDDDDDVVRAAAAEAL 87
 
Name Accession Description Interval E-value
Importin_rep_6 pfam18829
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 766-868 1.40e-24

Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.


Pssm-ID: 465881  Cd Length: 110  Bit Score: 99.48  E-value: 1.40e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   766 ITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDRHGD--GDEYNENIDEEEDFTDED---LLDEINK 840
Cdd:pfam18829    1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEErkDDDYDEEVEEDLEEEEETdeeLLSEINK 80

                           90       100
                   ....*....|....*....|....*...
gi 767201008   841 SIAAVLKTTNGHYLKNLENIWSMINTFL 868
Cdd:pfam18829   81 AIHAIFKTHKTAFLPYFEQLLPTVVAFL 108
Importin_rep_4 pfam18808
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 274-365 1.84e-23

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.


Pssm-ID: 408579  Cd Length: 90  Bit Score: 95.61  E-value: 1.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   274 NKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVsiddDDAAEW-IESDDTDDEEEVTYDHARQAL 352
Cdd:pfam18808    1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEV----DDAEDWyTSDDLDDDDNEDNYVFGEQAL 76

                           90
                   ....*....|...
gi 767201008   353 DRVALKLGGEYLA 365
Cdd:pfam18808   77 DRLACRLGGKALL 89
Importin_rep_5 pfam18816
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 1001-1054 1.98e-16

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.


Pssm-ID: 465877  Cd Length: 52  Bit Score: 74.05  E-value: 1.98e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767201008  1001 DKEAASFNYQFLSQLIENNSPIVCaqSNISAVVDSVIQALNERSLTEREGQTVI 1054
Cdd:pfam18816    1 DEEAAPFAYRFLAELIEQNHPAVT--SQIPKVVDSVVQALEHKSLSGKTAERVV 52
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 381-435 1.00e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.12  E-value: 1.00e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   381 WRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQI 435
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 403-475 2.49e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.09  E-value: 2.49e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   403 IGEI--PKILDMVIPLINDPHPRVQYGCCNVLGQISTdfspfiqrtahDRILPALISKLTSECTSRVQTHAAAAL 475
Cdd:pfam13646   24 LGRIgdPEAVPALLELLKDEDPAVRRAAAEALGKIGD-----------PEALPALLELLRDDDDDVVRAAAAEAL 87
HEAT COG1413
HEAT repeat [General function prediction only];
403-493 7.30e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.07  E-value: 7.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008  403 IGEI--PKILDMVIPLINDPHPRVQYGCCNVLGQIstdfspfiqrtAHDRILPALISKLTSEcTSRVQTHAAAALVNFSE 480
Cdd:COG1413     9 LGRLgdPAAVPALIAALADEDPDVRAAAARALGRL-----------GDPRAVPALLEALKDP-DPEVRAAAAEALGRIGD 76

                          90
                  ....*....|...
gi 767201008  481 FASKDILEPYLDS 493
Cdd:COG1413    77 PEAVPALIAALKD 89
 
Name Accession Description Interval E-value
Importin_rep_6 pfam18829
Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 766-868 1.40e-24

Importin repeat 6; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry represents two consecutive repeat units and includes sequences captured by pfam18808.


Pssm-ID: 465881  Cd Length: 110  Bit Score: 99.48  E-value: 1.40e-24
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   766 ITQVYHNSLVNGIKVMGDNCLSEDQLAAFTKGVSANLTDTYERMQDRHGD--GDEYNENIDEEEDFTDED---LLDEINK 840
Cdd:pfam18829    1 VLAEYYSSLAECIEVLGPNCLSDEQMEEFIKAINSNLTEYFERVKEREEErkDDDYDEEVEEDLEEEEETdeeLLSEINK 80

                           90       100
                   ....*....|....*....|....*...
gi 767201008   841 SIAAVLKTTNGHYLKNLENIWSMINTFL 868
Cdd:pfam18829   81 AIHAIFKTHKTAFLPYFEQLLPTVVAFL 108
Importin_rep_4 pfam18808
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 274-365 1.84e-23

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit.


Pssm-ID: 408579  Cd Length: 90  Bit Score: 95.61  E-value: 1.84e-23
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008   274 NKDLEPPARTTALELLTVFSENAPQMCKSNQNYGQTLVMVTLIMMTEVsiddDDAAEW-IESDDTDDEEEVTYDHARQAL 352
Cdd:pfam18808    1 NKDLDDAARQVALELLVTLAEAAPGMCRKQPQFTNALVPICLSMMTEV----DDAEDWyTSDDLDDDDNEDNYVFGEQAL 76

                           90
                   ....*....|...
gi 767201008   353 DRVALKLGGEYLA 365
Cdd:pfam18808   77 DRLACRLGGKALL 89
Importin_rep_5 pfam18816
Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem ...
 1001-1054 1.98e-16

Importin repeat; The importin subunit beta-3 has a superhelical structure composed of tandem repeats structurally similar to HEAT repeats. This Pfam entry includes a single repeat unit and includes sequences not captured by pfam18808.


Pssm-ID: 465877  Cd Length: 52  Bit Score: 74.05  E-value: 1.98e-16
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 767201008  1001 DKEAASFNYQFLSQLIENNSPIVCaqSNISAVVDSVIQALNERSLTEREGQTVI 1054
Cdd:pfam18816    1 DEEAAPFAYRFLAELIEQNHPAVT--SQIPKVVDSVVQALEHKSLSGKTAERVV 52
HEAT_EZ pfam13513
HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats ...
 381-435 1.00e-03

HEAT-like repeat; The HEAT repeat family is related to armadillo/beta-catenin-like repeats (see pfam00514). These EZ repeats are found in subunits of cyanobacterial phycocyanin lyase and other proteins and probably carry out a scaffolding role.


Pssm-ID: 463906 [Multi-domain]  Cd Length: 55  Bit Score: 38.12  E-value: 1.00e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   381 WRERFAAMMALSSAAEGCADVLIGEIPKILDMVIPLINDPHPRVQYGCCNVLGQI 435
Cdd:pfam13513    1 WRVREAAALALGSLAEGGPDLLAPAVPELLPALLPLLNDDSDLVREAAAWALGRL 55
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 403-475 2.49e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 38.09  E-value: 2.49e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 767201008   403 IGEI--PKILDMVIPLINDPHPRVQYGCCNVLGQISTdfspfiqrtahDRILPALISKLTSECTSRVQTHAAAAL 475
Cdd:pfam13646   24 LGRIgdPEAVPALLELLKDEDPAVRRAAAEALGKIGD-----------PEALPALLELLRDDDDDVVRAAAAEAL 87
HEAT COG1413
HEAT repeat [General function prediction only];
403-493 7.30e-03

HEAT repeat [General function prediction only];


Pssm-ID: 441023 [Multi-domain]  Cd Length: 137  Bit Score: 38.07  E-value: 7.30e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 767201008  403 IGEI--PKILDMVIPLINDPHPRVQYGCCNVLGQIstdfspfiqrtAHDRILPALISKLTSEcTSRVQTHAAAALVNFSE 480
Cdd:COG1413     9 LGRLgdPAAVPALIAALADEDPDVRAAAARALGRL-----------GDPRAVPALLEALKDP-DPEVRAAAAEALGRIGD 76

                          90
                  ....*....|...
gi 767201008  481 FASKDILEPYLDS 493
Cdd:COG1413    77 PEAVPALIAALKD 89
HEAT_2 pfam13646
HEAT repeats; This family includes multiple HEAT repeats.
 416-493 7.82e-03

HEAT repeats; This family includes multiple HEAT repeats.


Pssm-ID: 433376 [Multi-domain]  Cd Length: 88  Bit Score: 36.55  E-value: 7.82e-03
                           10        20        30        40        50        60        70
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 767201008   416 LINDPHPRVQYGCCNVLGQIstdfspfiqrtAHDRILPALISKLTSECtSRVQTHAAAALVNFSEFASKDILEPYLDS 493
Cdd:pfam13646    8 LLRDPDPEVRAAAIRALGRI-----------GDPEAVPALLELLKDED-PAVRRAAAEALGKIGDPEALPALLELLRD 73
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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