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Conserved domains on  [gi|763712377|gb|AJQ30573|]
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chromosomal replication initiator protein DnaA, partial [Leuconostoc mesenteroides]

Protein Classification

dnaA superfamily protein( domain architecture ID 1903222)

dnaA superfamily protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
dnaA super family cl42516
chromosomal replication initiator protein DnaA;
1-162 1.48e-95

chromosomal replication initiator protein DnaA;


The actual alignment was detected with superfamily member PRK00149:

Pssm-ID: 455861 [Multi-domain]  Cd Length: 401  Bit Score: 281.64  E-value: 1.48e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:PRK00149  66 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFV 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:PRK00149 146 NALR--NNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWG 223


                 ..
gi 763712377 161 IM 162
Cdd:PRK00149 224 LT 225
 
Name Accession Description Interval E-value
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-162 1.48e-95

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 281.64  E-value: 1.48e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:PRK00149  66 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFV 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:PRK00149 146 NALR--NNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWG 223


                 ..
gi 763712377 161 IM 162
Cdd:PRK00149 224 LT 225
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 1-162 5.20e-91

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 271.33  E-value: 5.20e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:TIGR00362 104 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFV 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:TIGR00362 184 NALR--NNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWG 261


                  ..
gi 763712377  161 IM 162
Cdd:TIGR00362 262 LV 263
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
1-160 1.91e-86

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 255.12  E-value: 1.91e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:COG0593    1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:COG0593   81 NAIR--NNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWG 158
Bac_DnaA pfam00308
Bacterial dnaA protein;
1-161 1.73e-79

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 234.53  E-value: 1.73e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:pfam00308  81 DAIR--DNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWG 158


                  .
gi 763712377  161 I 161
Cdd:pfam00308 159 L 159
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 15-160 1.85e-18

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 76.80  E-value: 1.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  15 GNENAYAVARAVADEPgqVYNPYLIYGGVGLGKTHLMQAIgnAYAVSTPSAHIKYATAEDFLNDFTESLRAGDGATAA-- 92
Cdd:cd00009    2 GQEEAIEALREALELP--PPKNLLLYGPPGTGKTTLARAI--ANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLlf 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 763712377  93 FKQEYRSVDLLLVDDIQFWS-GKEKVQEEFFNTFNVLTK---NGKQIVMTSDKLP-TEIVDLQTRLTSRFEAG 160
Cdd:cd00009   78 ELAEKAKPGVLFIDEIDSLSrGAQNALLRVLETLNDLRIdreNVRVIGATNRPLLgDLDRALYDRLDIRIVIP 150
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 35-158 2.97e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.06  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    35 NPYLIYGGVGLGKTHLMQAIGNAYAVstPSAHIKYATAEDFLNDFTESLRA------------GDGATAAFKQ-EYRSVD 101
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP--PGGGVIYIDGEDILEEVLDQLLLiivggkkasgsgELRLRLALALaRKLKPD 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 763712377   102 LLLVDDIQFWSGKEKVQEEFFNTFNVLTK-----NGKQIVMTSDKLPTEIvDLQTRLTSRFE 158
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLEELRLLLllkseKNLTVILTTNDEKDLG-PALLRRRFDRR 141
 
Name Accession Description Interval E-value
dnaA PRK00149
chromosomal replication initiator protein DnaA;
1-162 1.48e-95

chromosomal replication initiator protein DnaA;


Pssm-ID: 234667 [Multi-domain]  Cd Length: 401  Bit Score: 281.64  E-value: 1.48e-95
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:PRK00149  66 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNYILEKNPNAKVVYVTSEKFTNDFV 145

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:PRK00149 146 NALR--NNTMEEFKEKYRSVDVLLIDDIQFLAGKERTQEEFFHTFNALHEAGKQIVLTSDRPPKELPGLEERLRSRFEWG 223


                 ..
gi 763712377 161 IM 162
Cdd:PRK00149 224 LT 225
DnaA TIGR00362
chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; ...
 1-162 5.20e-91

chromosomal replication initiator protein DnaA; DnaA is involved in DNA biosynthesis; initiation of chromosome replication and can also be transcription regulator. The C-terminal of the family hits the pfam bacterial DnaA (bac_dnaA) domain family. For a review, see Kaguni (2006). [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 273037 [Multi-domain]  Cd Length: 437  Bit Score: 271.33  E-value: 5.20e-91
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:TIGR00362 104 LNPKYTFDNFVVGKSNRLAHAAALAVAENPGKAYNPLFIYGGVGLGKTHLLHAIGNEILENNPNAKVLYVSSEKFTNDFV 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:TIGR00362 184 NALR--NNKMEEFKEKYRSVDLLLIDDIQFLAGKERTQEEFFHTFNALHENNKQIVLTSDRPPKELPGLEDRLRSRFEWG 261


                  ..
gi 763712377  161 IM 162
Cdd:TIGR00362 262 LV 263
DnaA COG0593
Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];
1-160 1.91e-86

Chromosomal replication initiation ATPase DnaA [Replication, recombination and repair];


Pssm-ID: 440358 [Multi-domain]  Cd Length: 303  Bit Score: 255.12  E-value: 1.91e-86
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:COG0593    1 LNPRYTFDNFVVGPSNRLAHAAALAVAEWPGKAYNPLFLYGGVGLGKTHLLHAIGNEALENNPGARVVYLTAEEFTNDFI 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:COG0593   81 NAIR--NNTIEEFKEKYRSVDVLLIDDIQFLAGKEATQEEFFHTFNALREAGKQIVLTSDRPPKELPGLEERLRSRLEWG 158
Bac_DnaA pfam00308
Bacterial dnaA protein;
1-161 1.73e-79

Bacterial dnaA protein;


Pssm-ID: 278724 [Multi-domain]  Cd Length: 219  Bit Score: 234.53  E-value: 1.73e-79
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIKYATAEDFLNDFT 80
Cdd:pfam00308   1 LNPRYTFENFVIGPSNRFAHAAALTVAKAPGKAYNPLFIYGGVGLGKTHLLHAIGNYALQNAPNLRVVYLTAEEFLNDFV 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   81 ESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEAG 160
Cdd:pfam00308  81 DAIR--DNKTNQFKEKYRNVDVLLIDDIQFLAGKEGTQEEFFHTFNALHESGKQIVFSSDRPPKELEELEDRLRSRFQWG 158


                  .
gi 763712377  161 I 161
Cdd:pfam00308 159 L 159
dnaA PRK14086
chromosomal replication initiator protein DnaA;
1-162 1.86e-62

chromosomal replication initiator protein DnaA;


Pssm-ID: 237605 [Multi-domain]  Cd Length: 617  Bit Score: 202.36  E-value: 1.86e-62
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNaYAVST-PSAHIKYATAEDFLNDF 79
Cdd:PRK14086 281 LNPKYTFDTFVIGASNRFAHAAAVAVAEAPAKAYNPLFIYGESGLGKTHLLHAIGH-YARRLyPGTRVRYVSSEEFTNEF 359

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  80 TESLRagDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSRFEA 159
Cdd:PRK14086 360 INSIR--DGKGDSFRRRYREMDILLVDDIQFLEDKESTQEEFFHTFNTLHNANKQIVLSSDRPPKQLVTLEDRLRNRFEW 437


                 ...
gi 763712377 160 GIM 162
Cdd:PRK14086 438 GLI 440
PRK12422 PRK12422
chromosomal replication initiator protein DnaA;
1-163 4.71e-37

chromosomal replication initiator protein DnaA;


Pssm-ID: 183521 [Multi-domain]  Cd Length: 445  Bit Score: 131.88  E-value: 4.71e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGSGNENAYAVARAVADEP----GQVYNPYLIYGGVGLGKTHLMQAIgnAYAVSTPSAHIKYATAEDFL 76
Cdd:PRK12422 104 LDPLMTFANFLVTPENDLPHRILQEFTKVSeqgkGFPFNPIYLFGPEGSGKTHLMQAA--VHALRESGGKILYVRSELFT 181

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  77 NDFTESLRAGDgaTAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQTRLTSR 156
Cdd:PRK12422 182 EHLVSAIRSGE--MQRFRQFYRNVDALFIEDIEVFSGKGATQEEFFHTFNSLHTEGKLIVISSTCAPQDLKAMEERLISR 259


                 ....*..
gi 763712377 157 FEAGIMM 163
Cdd:PRK12422 260 FEWGIAI 266
AAA cd00009
The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily ...
 15-160 1.85e-18

The AAA+ (ATPases Associated with a wide variety of cellular Activities) superfamily represents an ancient group of ATPases belonging to the ASCE (for additional strand, catalytic E) division of the P-loop NTPase fold. The ASCE division also includes ABC, RecA-like, VirD4-like, PilT-like, and SF1/2 helicases. Members of the AAA+ ATPases function as molecular chaperons, ATPase subunits of proteases, helicases, or nucleic-acid stimulated ATPases. The AAA+ proteins contain several distinct features in addition to the conserved alpha-beta-alpha core domain structure and the Walker A and B motifs of the P-loop NTPases.


Pssm-ID: 99707 [Multi-domain]  Cd Length: 151  Bit Score: 76.80  E-value: 1.85e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  15 GNENAYAVARAVADEPgqVYNPYLIYGGVGLGKTHLMQAIgnAYAVSTPSAHIKYATAEDFLNDFTESLRAGDGATAA-- 92
Cdd:cd00009    2 GQEEAIEALREALELP--PPKNLLLYGPPGTGKTTLARAI--ANELFRPGAPFLYLNASDLLEGLVVAELFGHFLVRLlf 77

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 763712377  93 FKQEYRSVDLLLVDDIQFWS-GKEKVQEEFFNTFNVLTK---NGKQIVMTSDKLP-TEIVDLQTRLTSRFEAG 160
Cdd:cd00009   78 ELAEKAKPGVLFIDEIDSLSrGAQNALLRVLETLNDLRIdreNVRVIGATNRPLLgDLDRALYDRLDIRIVIP 150
DnaA_homol_Hda TIGR03420
DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). ...
 1-155 1.89e-18

DnaA regulatory inactivator Hda; Members of this protein family are Hda (Homologous to DnaA). These proteins are about half the length of DnaA and homologous over length of Hda. In the model species Escherichia coli, the initiation of DNA replication requires DnaA bound to ATP rather than ADP; Hda helps facilitate the conversion of DnaA-ATP to DnaA-ADP. [DNA metabolism, DNA replication, recombination, and repair]


Pssm-ID: 274571 [Multi-domain]  Cd Length: 226  Bit Score: 78.77  E-value: 1.89e-18
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    1 LNPDFTFEKFvIGSGNENAYAVARAVADEPGQvyNPYLIYGGVGLGKTHLMQAIGNAYA-VSTPSAHIKYATAEDFLNDF 79
Cdd:TIGR03420   8 LPDDPTFDNF-YAGGNAELLAALRQLAAGKGD--RFLYLWGESGSGKSHLLQAACAAAEeRGKSAIYLPLAELAQADPEV 84

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   80 TESLRAgdgataafkqeyrsVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEIV----DLQTRLTS 155
Cdd:TIGR03420  85 LEGLEQ--------------ADLVCLDDVEAIAGQPEWQEALFHLYNRVREAGGRLLIAGRAAPAQLPlrlpDLRTRLAW 150
PRK08116 PRK08116
hypothetical protein; Validated
 6-156 4.25e-11

hypothetical protein; Validated


Pssm-ID: 236153 [Multi-domain]  Cd Length: 268  Bit Score: 59.26  E-value: 4.25e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   6 TFEKFVIGSGNENAYAVARAVADEPGQVYN---PYLIYGGVGLGKTHLMQAIGNAY--------AVSTPSahikyataed 74
Cdd:PRK08116  83 TFENFLFDKGSEKAYKIARKYVKKFEEMKKenvGLLLWGSVGTGKTYLAACIANELiekgvpviFVNFPQ---------- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  75 FLNDFTESLR-AGDGATAAFKQEYRSVDLLLVDDIQFWSGKEKVQEEFFNTFNVLTKNGKQIVMTSDKLPTEivdLQTRL 153
Cdd:PRK08116 153 LLNRIKSTYKsSGKEDENEIIRSLVNADLLILDDLGAERDTEWAREKVYNIIDSRYRKGLPTIVTTNLSLEE---LKNQY 229


                 ...
gi 763712377 154 TSR 156
Cdd:PRK08116 230 GKR 232
DnaC COG1484
DNA replication protein DnaC [Replication, recombination and repair];
38-108 5.85e-11

DNA replication protein DnaC [Replication, recombination and repair];


Pssm-ID: 441093 [Multi-domain]  Cd Length: 242  Bit Score: 58.64  E-value: 5.85e-11
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 763712377  38 LIYGGVGLGKTHLMQAIGNA-----YAVstpsahiKYATAEDFLNDFTESLraGDGATAAFKQEYRSVDLLLVDDI 108
Cdd:COG1484  103 ILLGPPGTGKTHLAIALGHEacragYRV-------RFTTAPDLVNELKEAR--ADGRLERLLKRLAKVDLLILDEL 169
PRK08903 PRK08903
DnaA regulatory inactivator Hda; Validated
 6-153 4.65e-09

DnaA regulatory inactivator Hda; Validated


Pssm-ID: 236347 [Multi-domain]  Cd Length: 227  Bit Score: 53.44  E-value: 4.65e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   6 TFEKFVIGSgneNAYAVARAVADEPGQVYNPYL-IYGGVGLGKTHLMQAIGNAYAVSTPSAHikYATAedflndfteslr 84
Cdd:PRK08903  16 TFDNFVAGE---NAELVARLRELAAGPVADRFFyLWGEAGSGRSHLLQALVADASYGGRNAR--YLDA------------ 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 763712377  85 AGDGATAAFKqeyRSVDLLLVDDIQFWSGKEkvQEEFFNTFNVLTKNGK-QIVMTSDKLPTEIV---DLQTRL 153
Cdd:PRK08903  79 ASPLLAFDFD---PEAELYAVDDVERLDDAQ--QIALFNLFNRVRAHGQgALLVAGPAAPLALPlreDLRTRL 146
PRK06835 PRK06835
DNA replication protein DnaC; Validated
 38-156 1.16e-08

DNA replication protein DnaC; Validated


Pssm-ID: 235871 [Multi-domain]  Cd Length: 329  Bit Score: 52.59  E-value: 1.16e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  38 LIYGGVGLGKTHLMQAIGNA-----YAVstpsahIkYATAEDFLNDFTEsLRAGDGATAAFKQEY-RSVDLLLVDDIqfw 111
Cdd:PRK06835 187 LFYGNTGTGKTFLSNCIAKElldrgKSV------I-YRTADELIEILRE-IRFNNDKELEEVYDLlINCDLLIIDDL--- 255

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 763712377 112 sGKEKVQE----EFFNTFNVLTKNGKQIVMTSDKLPTEIVDLQT-RLTSR 156
Cdd:PRK06835 256 -GTEKITEfsksELFNLINKRLLRQKKMIISTNLSLEELLKTYSeRISSR 304
AAA smart00382
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ...
 35-158 2.97e-08

ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.


Pssm-ID: 214640 [Multi-domain]  Cd Length: 148  Bit Score: 50.06  E-value: 2.97e-08
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377    35 NPYLIYGGVGLGKTHLMQAIGNAYAVstPSAHIKYATAEDFLNDFTESLRA------------GDGATAAFKQ-EYRSVD 101
Cdd:smart00382   3 EVILIVGPPGSGKTTLARALARELGP--PGGGVIYIDGEDILEEVLDQLLLiivggkkasgsgELRLRLALALaRKLKPD 80

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 763712377   102 LLLVDDIQFWSGKEKVQEEFFNTFNVLTK-----NGKQIVMTSDKLPTEIvDLQTRLTSRFE 158
Cdd:smart00382  81 VLILDEITSLLDAEQEALLLLLEELRLLLllkseKNLTVILTTNDEKDLG-PALLRRRFDRR 141
PRK12377 PRK12377
putative replication protein; Provisional
 11-117 3.95e-07

putative replication protein; Provisional


Pssm-ID: 183482 [Multi-domain]  Cd Length: 248  Bit Score: 47.91  E-value: 3.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  11 VIGSGNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIkyATAEDFLNDFTESLRAGDgAT 90
Cdd:PRK12377  78 VQNDGQRYALSQAKSIADELMTGCTNFVFSGKPGTGKNHLAAAIGNRLLAKGRSVIV--VTVPDVMSRLHESYDNGQ-SG 154

                         90       100
                 ....*....|....*....|....*....
gi 763712377  91 AAFKQEYRSVDLLLVDDI--QFWSGKEKV 117
Cdd:PRK12377 155 EKFLQELCKVDLLVLDEIgiQRETKNEQV 183
PRK06921 PRK06921
hypothetical protein; Provisional
 31-156 2.42e-06

hypothetical protein; Provisional


Pssm-ID: 180750 [Multi-domain]  Cd Length: 266  Bit Score: 45.93  E-value: 2.42e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377  31 GQVYNPYLIYGGVGLGKTHLMQAIGNaYAVSTPSAHIKYATAEDFLNDFTESLRAGDGATAAFKQeyrsVDLLLVDDIqF 110
Cdd:PRK06921 114 ESRKNSIALLGQPGSGKTHLLTAAAN-ELMRKKGVPVLYFPFVEGFGDLKDDFDLLEAKLNRMKK----VEVLFIDDL-F 187

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 763712377 111 W--SGKEKVQE-EFFNTFNVLTK---NGKQIVMTSDKLPTEIVDLQTRLTSR 156
Cdd:PRK06921 188 KpvNGKPRATEwQIEQMYSVLNYrylNHKPILISSELTIDELLDIDEALGSR 239
PRK07952 PRK07952
DNA replication protein DnaC; Validated
 1-117 1.84e-05

DNA replication protein DnaC; Validated


Pssm-ID: 181180 [Multi-domain]  Cd Length: 244  Bit Score: 43.22  E-value: 1.84e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 763712377   1 LNPDFTFEKFVIGS-GNENAYAVARAVADEPGQVYNPYLIYGGVGLGKTHLMQAIGNAYAVSTPSAHIkyATAEDFLNDF 79
Cdd:PRK07952  65 LHQNCSFENYRVECeGQMNALSKARQYVEEFDGNIASFIFSGKPGTGKNHLAAAICNELLLRGKSVLI--ITVADIMSAM 142

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 763712377  80 TESLRAGDGATAAFKQEYRSVDLLLVDDI--QFWSGKEKV 117
Cdd:PRK07952 143 KDTFSNSETSEEQLLNDLSNVDLLVIDEIgvQTESRYEKV 182
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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