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penicillin binding transpeptidase domain protein [Burkholderia cepacia]
Protein Classification
peptidoglycan D,D-transpeptidase FtsI family protein ( domain architecture ID 11433609 )
peptidoglycan D,D-transpeptidase FtsI (penicillin-binding protein (PBP) 2) family protein is a membrane-associated enzyme that is most likely involved in the synthesis of cross-linked peptidoglycan
List of domain hits
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
22-566
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 623.38
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 22 L PMW R SK L VVFMLFMA F VA L AA R A F WI Q GPGNAF Y QKQG E SRYQ RT IEL PA T RG K I L DRNG L VLAT SL PV RAIW A I P DA V 101
Cdd:COG0768 9 L FRR R LL L LFLLVLLL F LL L VG R L F YL Q VVEGDE Y AELA E ENRI RT VPI PA P RG L I Y DRNG N VLAT NV PV YSLY A D P EE V 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 102 P D DLDA dk INQ L G KLLG MTSK ELR V KL SEDKG F - VY V KR QVPIDV A DKVA AL DI PG I Y QRN EYKR F YP E GE IT AH LI G FT 180
Cdd:COG0768 89 K D PEET -- AEK L A KLLG LDPE ELR K KL KKKSR F p VY L KR NLSPEE A ARIR AL KL PG V Y VEA EYKR Y YP Y GE LA AH VL G YV 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 181 NV ---- EDE G QE G V E LGDQKM L S GT S G M RRV IK D RM G HI I E D VA E QI PP HN G T D VD L S IDS KI Q Y IA YAN LK A AVE KF KA 256
Cdd:COG0768 167 GE ingg DGI G KS G L E KAYEDL L R GT P G K RRV EV D AR G RV I R D LG E EK PP VP G K D LV L T IDS DL Q K IA EEA LK K AVE EY KA 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 257 K A GA AM V V D VR TGE V LA LVN YP TYN PN DRSRMTG E Q LRNR IMTDVF EPGS IM KPFT VSL AL DLHRV TP N T LV e TGN G HFV 336
Cdd:COG0768 247 K S GA VV V M D PK TGE I LA MAS YP SFD PN LFVGGPD E P LRNR AVQGTY EPGS TF KPFT AAA AL EEGVI TP D T TF - DCP G YYR 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 337 LD G AP I T D -- DA G F GTLT VGGVIQ KSSN I G AT K I A MTMRPEEMWNMYTSI GLGQ APKVGF PG AVA G R L RPW K S W RRI E Q A 414
Cdd:COG0768 326 VG G RT I R D wd RG G H GTLT LTEALA KSSN V G FY K L A LRLGIDKLYDYLKKF GLGQ KTGIDL PG EAS G L L PSP K R W YPG E T A 405
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 415 TMS Y G Y GLSV SLF QLA R AY T AIA HD G E L MPVTIF K -- T DP N ------ Q P IAGTQ V FN P T TA RE VR AML E T VV - A PGGT SP 485
Cdd:COG0768 406 TMS I G Q GLSV TPL QLA Q AY A AIA NG G V L VKPHLV K ei V DP D gevvke E P EVLRR V IS P E TA ET VR EGM E G VV n E PGGT AR 485
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 486 D AA V PGYRV G GK S GTA YK --- HE G HG Y TRKYR ASFVG M AP MP NPR VVI AV S V DE P T a G SHF GG Q V SG PVF SA I AGDTM R A 562
Cdd:COG0768 486 R AA I PGYRV A GK T GTA QV vdi GN G GY Y KGRHI ASFVG F AP AD NPR YAV AV V V EN P G - G GAY GG T V AA PVF RE I MEAYL R L 564
....
gi 757910760 563 L NV P 566
Cdd:COG0768 565 L GP P 568
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
22-566
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 623.38
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 22 L PMW R SK L VVFMLFMA F VA L AA R A F WI Q GPGNAF Y QKQG E SRYQ RT IEL PA T RG K I L DRNG L VLAT SL PV RAIW A I P DA V 101
Cdd:COG0768 9 L FRR R LL L LFLLVLLL F LL L VG R L F YL Q VVEGDE Y AELA E ENRI RT VPI PA P RG L I Y DRNG N VLAT NV PV YSLY A D P EE V 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 102 P D DLDA dk INQ L G KLLG MTSK ELR V KL SEDKG F - VY V KR QVPIDV A DKVA AL DI PG I Y QRN EYKR F YP E GE IT AH LI G FT 180
Cdd:COG0768 89 K D PEET -- AEK L A KLLG LDPE ELR K KL KKKSR F p VY L KR NLSPEE A ARIR AL KL PG V Y VEA EYKR Y YP Y GE LA AH VL G YV 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 181 NV ---- EDE G QE G V E LGDQKM L S GT S G M RRV IK D RM G HI I E D VA E QI PP HN G T D VD L S IDS KI Q Y IA YAN LK A AVE KF KA 256
Cdd:COG0768 167 GE ingg DGI G KS G L E KAYEDL L R GT P G K RRV EV D AR G RV I R D LG E EK PP VP G K D LV L T IDS DL Q K IA EEA LK K AVE EY KA 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 257 K A GA AM V V D VR TGE V LA LVN YP TYN PN DRSRMTG E Q LRNR IMTDVF EPGS IM KPFT VSL AL DLHRV TP N T LV e TGN G HFV 336
Cdd:COG0768 247 K S GA VV V M D PK TGE I LA MAS YP SFD PN LFVGGPD E P LRNR AVQGTY EPGS TF KPFT AAA AL EEGVI TP D T TF - DCP G YYR 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 337 LD G AP I T D -- DA G F GTLT VGGVIQ KSSN I G AT K I A MTMRPEEMWNMYTSI GLGQ APKVGF PG AVA G R L RPW K S W RRI E Q A 414
Cdd:COG0768 326 VG G RT I R D wd RG G H GTLT LTEALA KSSN V G FY K L A LRLGIDKLYDYLKKF GLGQ KTGIDL PG EAS G L L PSP K R W YPG E T A 405
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 415 TMS Y G Y GLSV SLF QLA R AY T AIA HD G E L MPVTIF K -- T DP N ------ Q P IAGTQ V FN P T TA RE VR AML E T VV - A PGGT SP 485
Cdd:COG0768 406 TMS I G Q GLSV TPL QLA Q AY A AIA NG G V L VKPHLV K ei V DP D gevvke E P EVLRR V IS P E TA ET VR EGM E G VV n E PGGT AR 485
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 486 D AA V PGYRV G GK S GTA YK --- HE G HG Y TRKYR ASFVG M AP MP NPR VVI AV S V DE P T a G SHF GG Q V SG PVF SA I AGDTM R A 562
Cdd:COG0768 486 R AA I PGYRV A GK T GTA QV vdi GN G GY Y KGRHI ASFVG F AP AD NPR YAV AV V V EN P G - G GAY GG T V AA PVF RE I MEAYL R L 564
....
gi 757910760 563 L NV P 566
Cdd:COG0768 565 L GP P 568
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
25-568
3.62e-148
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 440.41
E-value: 3.62e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 25 WR SK L VVFMLFM A F V A L AA R AF W I Q GPGNAFYQKQ G ES R YQ R TI E LPAT RG K I L DR N G LV LA T S L PV R AIWA I P DA V P D - 103
Cdd:PRK15105 21 WR FA L LCGCILL A L V F L LG R VA W L Q VINPDMLVRE G DM R SL R VQ E VSTS RG M I T DR S G RP LA V S V PV K AIWA D P KE V H D a 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 104 -- DLDA D KINQ L GKL L GMTSKE L RVKLSED - KG - F V Y VK RQV PI D V AD KVAA L DI PGI YQ R N E YK R F YP E GE I TAHLIGF 179
Cdd:PRK15105 101 gg ISVD D RWKA L ADA L NIPLDQ L SARINAN p KG r F I Y LA RQV NP D M AD YIKK L KL PGI HL R E E SR R Y YP S GE V TAHLIGF 180
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 180 TNV EDE G Q EGVE LGDQ K M L S G TS G M R R V I KDR M G HI IED VA -- EQIPP HN gtd VD LSID SKI Q YIA Y AN L KA AV EKF KA K 257
Cdd:PRK15105 181 TNV DSQ G I EGVE KSFD K W L T G QP G E R I V R KDR Y G RV IED IS st DSQAA HN --- LA LSID ERL Q ALV Y RE L NN AV AFN KA E 257
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 258 A G A A MV VDV R TGEVLA LV N Y P T YNPN DR S RMTGEQL RNR IM TDVFEPGS IM KP FT V SL AL DLHR V TP N TLVE T GN gh FVL 337
Cdd:PRK15105 258 S G S A VL VDV N TGEVLA MA N S P S YNPN NL S GTPKDAM RNR AI TDVFEPGS TV KP MV V MT AL QRGV V KE N SVLN T VP -- YRI 335
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 338 D G AP I T D D A GFGT LT VG GV I QKSSN I G AT K I A MT M RPEEMWNM Y TSI GLG Q A PKV G FP G AVA G r L R P W K S - W RR IE Q AT M 416
Cdd:PRK15105 336 N G HE I K D V A RYSE LT LT GV L QKSSN V G VS K L A LA M PSSALVDT Y SRF GLG K A TNL G LV G ERS G - L Y P Q K Q r W SD IE R AT F 414
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 417 S Y GYGL S V SLF QLAR A Y TA I AHD G ELM P VT I F K T DP nq P IA G TQ VF NPTTA R E V RA M L E T V VA PGG TSPD AA VP GYR VGG 496
Cdd:PRK15105 415 S F GYGL M V TPL QLAR V Y AT I GSY G IYR P LS I T K V DP -- P VP G ER VF PESIV R T V VH M M E S V AL PGG GGVK AA IK GYR IAI 492
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757910760 497 K S GTA Y K HEGH G - Y TR KY R A SFV G M AP MPN PR VVIA V SVDE P T AG SHF GG Q VS G PVF S AI A G DTM R AL N VP P N 568
Cdd:PRK15105 493 K T GTA K K VGPD G r Y IN KY I A YTA G V AP ASQ PR FALV V VIND P Q AG KYY GG A VS A PVF G AI M G GVL R TM N IE P D 565
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
26-555
2.53e-95
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 304.06
E-value: 2.53e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 26 R SKLVVFMLFMA F VA LAAR A F WI Q GPGNAF Y QKQG E SRYQ R TIEL P AT RG K ILDRNG LV LA TSL P VRAIWAI P DA V p DDL 105
Cdd:TIGR03423 2 R ALVLGGLVLAL F GV LAAR L F YL Q VIRGEE Y ATLS E DNRI R LVPI P PP RG L ILDRNG VL LA DNR P SFSLEIV P EK V - DDL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 106 DA d KINQ L G KLL GMTSKELRVK L S E D K --- G F -- VYV K RQVPIDVADKV A A -- LDI PG IYQRNEY KR F YP E GE IT AH LI G 178
Cdd:TIGR03423 81 DA - TLDR L A KLL DLDPEDIARF L K E L K rsr R F ep IPL K SDLTEEEVARF A V nq YRL PG VEIEARL KR Y YP Y GE LA AH VL G 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 179 FTN --------- V E DE -------- G QE G V E LGDQKM L S G TS G M R R V IKDRM G HI I EDV a EQI PP HN G T D VD L S ID SKI Q y 241
Cdd:TIGR03423 160 YVG eineedler L E PA nyaggdyi G KS G I E KYYEDE L R G KP G Y R E V EVNAR G RV I RTL - SRV PP VP G K D LV L T ID ARL Q - 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 242 iayanl K AA VEKFKAKA GA AM V V D V RTGE V LA L V NY P TYN PN DRSR - MTGEQ ----------- L R NR IMTD V FE PGS IM K 309
Cdd:TIGR03423 238 ------ Q AA EKALGGRR GA VV V M D P RTGE I LA M V ST P SFD PN LFVD g ISSKD ykallndpdrp L L NR AIQG V YP PGS TF K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 310 P FTVSL AL DLHRV TP N T LV e TGN G H F V L D G APITDD -- A G F G TLTVGGV I QK S SNIGATKI A MTMRPEEMWNMYTSI G L G 387
Cdd:TIGR03423 312 P VVALA AL EEGVI TP E T RI - YCP G Y F Q L G G RRFRCW kr G G H G RVDLRKA I EE S CDVYFYQL A LRLGIDKIAEYAKRF G F G 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 388 Q APKVGF PG AVA G RL -- R P WK ------ S W RRIE qa T MSYGY G --- LS V SLF QLA R A YT A I A HD G E L MPVTIF K -- T DP N - 453
Cdd:TIGR03423 391 Q KTGIDL PG EKS G LV ps R E WK rkrfgq P W YPGD -- T LNVSI G qgy VL V TPL QLA V A TA A L A NG G K L YKPHLV K si E DP D g 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 454 ------- QPIAGTQVFN P TTARE VR - A M LET V VA PGGT SPD A AVP - G Y RVG GK S GTA ---------- Y KH E GHGYTRKYR 514
Cdd:TIGR03423 469 gvvrrte PEVLRPLPIS P ENLDV VR e G M RDV V NG PGGT ARR A RLG l P Y KMA GK T GTA qvvslkqgek Y DA E QIPERLRDH 548
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 757910760 515 A S FV GM AP MP NP RVVI AV S V D ept A G SH f G GQVSG P VFSA I 555
Cdd:TIGR03423 549 A L FV AF AP YD NP KIAV AV I V E --- H G GG - G SSAAA P IARK I 585
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
259-555
1.98e-72
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 234.62
E-value: 1.98e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 259 G A A M V V D VR TGEVLA L V NY P T Y N PN DR srmt GEQ LRNR IM T DVF EPGS IM KPFT VSL ALD LHRVT P NTLVETGN G HFV l D 338
Cdd:pfam00905 1 G S A V V L D PK TGEVLA M V GK P S Y D PN GF ---- IGP LRNR AV T SRY EPGS TF KPFT ALA ALD NGVLK P DETIFDWP G KQQ - G 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 339 G AP I ---- T D DA G F GTL T vg GVIQK SSN IGAT K I A MTMRPEEMWNMYTSI G L G QAPKV G F PG AV AG R L R P wk S W rr I E Q A 414
Cdd:pfam00905 76 G KS I gdwn Q D QV G I GTL R -- QALEY SSN WYMQ K L A QKLGADKLRSYLKKF G Y G NKTGI G L PG EN AG Y L T P -- Y W -- L E G A 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 415 T M S Y G Y GL SVSLF Q L A R AY T AIA HD G E L M P VTIF K TDP --- NQPIAGTQVFNPT TA RE V RA ML ET VV AP G GTSPD AAVPG 491
Cdd:pfam00905 150 T A S F G I GL TITPL Q Q A Q AY A AIA NG G K L V P PHLV K SIE dkv DPKVLNKLPISKS TA EK V KD ML RL VV ND G TGTGT AAVPG 229
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757910760 492 Y R V G GK S GTA --- YKHE G HG Y TRKYRAS FVG M AP MP NP RVVI AV SV D E P TAG sh F GG Q V SG P V F SA I 555
Cdd:pfam00905 230 Y K V A GK T GTA qva GPKG G GY Y DGAQIGW FVG Y AP AD NP KYAF AV LI D D P KRY -- Y GG K V AA P I F KD I 294
Name
Accession
Description
Interval
E-value
FtsI
COG0768 Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ...
22-566
0e+00
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain]
Cd Length: 568
Bit Score: 623.38
E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 22 L PMW R SK L VVFMLFMA F VA L AA R A F WI Q GPGNAF Y QKQG E SRYQ RT IEL PA T RG K I L DRNG L VLAT SL PV RAIW A I P DA V 101
Cdd:COG0768 9 L FRR R LL L LFLLVLLL F LL L VG R L F YL Q VVEGDE Y AELA E ENRI RT VPI PA P RG L I Y DRNG N VLAT NV PV YSLY A D P EE V 88
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 102 P D DLDA dk INQ L G KLLG MTSK ELR V KL SEDKG F - VY V KR QVPIDV A DKVA AL DI PG I Y QRN EYKR F YP E GE IT AH LI G FT 180
Cdd:COG0768 89 K D PEET -- AEK L A KLLG LDPE ELR K KL KKKSR F p VY L KR NLSPEE A ARIR AL KL PG V Y VEA EYKR Y YP Y GE LA AH VL G YV 166
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 181 NV ---- EDE G QE G V E LGDQKM L S GT S G M RRV IK D RM G HI I E D VA E QI PP HN G T D VD L S IDS KI Q Y IA YAN LK A AVE KF KA 256
Cdd:COG0768 167 GE ingg DGI G KS G L E KAYEDL L R GT P G K RRV EV D AR G RV I R D LG E EK PP VP G K D LV L T IDS DL Q K IA EEA LK K AVE EY KA 246
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 257 K A GA AM V V D VR TGE V LA LVN YP TYN PN DRSRMTG E Q LRNR IMTDVF EPGS IM KPFT VSL AL DLHRV TP N T LV e TGN G HFV 336
Cdd:COG0768 247 K S GA VV V M D PK TGE I LA MAS YP SFD PN LFVGGPD E P LRNR AVQGTY EPGS TF KPFT AAA AL EEGVI TP D T TF - DCP G YYR 325
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 337 LD G AP I T D -- DA G F GTLT VGGVIQ KSSN I G AT K I A MTMRPEEMWNMYTSI GLGQ APKVGF PG AVA G R L RPW K S W RRI E Q A 414
Cdd:COG0768 326 VG G RT I R D wd RG G H GTLT LTEALA KSSN V G FY K L A LRLGIDKLYDYLKKF GLGQ KTGIDL PG EAS G L L PSP K R W YPG E T A 405
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 415 TMS Y G Y GLSV SLF QLA R AY T AIA HD G E L MPVTIF K -- T DP N ------ Q P IAGTQ V FN P T TA RE VR AML E T VV - A PGGT SP 485
Cdd:COG0768 406 TMS I G Q GLSV TPL QLA Q AY A AIA NG G V L VKPHLV K ei V DP D gevvke E P EVLRR V IS P E TA ET VR EGM E G VV n E PGGT AR 485
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 486 D AA V PGYRV G GK S GTA YK --- HE G HG Y TRKYR ASFVG M AP MP NPR VVI AV S V DE P T a G SHF GG Q V SG PVF SA I AGDTM R A 562
Cdd:COG0768 486 R AA I PGYRV A GK T GTA QV vdi GN G GY Y KGRHI ASFVG F AP AD NPR YAV AV V V EN P G - G GAY GG T V AA PVF RE I MEAYL R L 564
....
gi 757910760 563 L NV P 566
Cdd:COG0768 565 L GP P 568
PRK15105
PRK15105 peptidoglycan synthase FtsI; Provisional
25-568
3.62e-148
peptidoglycan synthase FtsI; Provisional
Pssm-ID: 185060 [Multi-domain]
Cd Length: 578
Bit Score: 440.41
E-value: 3.62e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 25 WR SK L VVFMLFM A F V A L AA R AF W I Q GPGNAFYQKQ G ES R YQ R TI E LPAT RG K I L DR N G LV LA T S L PV R AIWA I P DA V P D - 103
Cdd:PRK15105 21 WR FA L LCGCILL A L V F L LG R VA W L Q VINPDMLVRE G DM R SL R VQ E VSTS RG M I T DR S G RP LA V S V PV K AIWA D P KE V H D a 100
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 104 -- DLDA D KINQ L GKL L GMTSKE L RVKLSED - KG - F V Y VK RQV PI D V AD KVAA L DI PGI YQ R N E YK R F YP E GE I TAHLIGF 179
Cdd:PRK15105 101 gg ISVD D RWKA L ADA L NIPLDQ L SARINAN p KG r F I Y LA RQV NP D M AD YIKK L KL PGI HL R E E SR R Y YP S GE V TAHLIGF 180
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 180 TNV EDE G Q EGVE LGDQ K M L S G TS G M R R V I KDR M G HI IED VA -- EQIPP HN gtd VD LSID SKI Q YIA Y AN L KA AV EKF KA K 257
Cdd:PRK15105 181 TNV DSQ G I EGVE KSFD K W L T G QP G E R I V R KDR Y G RV IED IS st DSQAA HN --- LA LSID ERL Q ALV Y RE L NN AV AFN KA E 257
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 258 A G A A MV VDV R TGEVLA LV N Y P T YNPN DR S RMTGEQL RNR IM TDVFEPGS IM KP FT V SL AL DLHR V TP N TLVE T GN gh FVL 337
Cdd:PRK15105 258 S G S A VL VDV N TGEVLA MA N S P S YNPN NL S GTPKDAM RNR AI TDVFEPGS TV KP MV V MT AL QRGV V KE N SVLN T VP -- YRI 335
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 338 D G AP I T D D A GFGT LT VG GV I QKSSN I G AT K I A MT M RPEEMWNM Y TSI GLG Q A PKV G FP G AVA G r L R P W K S - W RR IE Q AT M 416
Cdd:PRK15105 336 N G HE I K D V A RYSE LT LT GV L QKSSN V G VS K L A LA M PSSALVDT Y SRF GLG K A TNL G LV G ERS G - L Y P Q K Q r W SD IE R AT F 414
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 417 S Y GYGL S V SLF QLAR A Y TA I AHD G ELM P VT I F K T DP nq P IA G TQ VF NPTTA R E V RA M L E T V VA PGG TSPD AA VP GYR VGG 496
Cdd:PRK15105 415 S F GYGL M V TPL QLAR V Y AT I GSY G IYR P LS I T K V DP -- P VP G ER VF PESIV R T V VH M M E S V AL PGG GGVK AA IK GYR IAI 492
490 500 510 520 530 540 550
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 757910760 497 K S GTA Y K HEGH G - Y TR KY R A SFV G M AP MPN PR VVIA V SVDE P T AG SHF GG Q VS G PVF S AI A G DTM R AL N VP P N 568
Cdd:PRK15105 493 K T GTA K K VGPD G r Y IN KY I A YTA G V AP ASQ PR FALV V VIND P Q AG KYY GG A VS A PVF G AI M G GVL R TM N IE P D 565
pbp2_mrdA
TIGR03423 penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ...
26-555
2.53e-95
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain]
Cd Length: 592
Bit Score: 304.06
E-value: 2.53e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 26 R SKLVVFMLFMA F VA LAAR A F WI Q GPGNAF Y QKQG E SRYQ R TIEL P AT RG K ILDRNG LV LA TSL P VRAIWAI P DA V p DDL 105
Cdd:TIGR03423 2 R ALVLGGLVLAL F GV LAAR L F YL Q VIRGEE Y ATLS E DNRI R LVPI P PP RG L ILDRNG VL LA DNR P SFSLEIV P EK V - DDL 80
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 106 DA d KINQ L G KLL GMTSKELRVK L S E D K --- G F -- VYV K RQVPIDVADKV A A -- LDI PG IYQRNEY KR F YP E GE IT AH LI G 178
Cdd:TIGR03423 81 DA - TLDR L A KLL DLDPEDIARF L K E L K rsr R F ep IPL K SDLTEEEVARF A V nq YRL PG VEIEARL KR Y YP Y GE LA AH VL G 159
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 179 FTN --------- V E DE -------- G QE G V E LGDQKM L S G TS G M R R V IKDRM G HI I EDV a EQI PP HN G T D VD L S ID SKI Q y 241
Cdd:TIGR03423 160 YVG eineedler L E PA nyaggdyi G KS G I E KYYEDE L R G KP G Y R E V EVNAR G RV I RTL - SRV PP VP G K D LV L T ID ARL Q - 237
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 242 iayanl K AA VEKFKAKA GA AM V V D V RTGE V LA L V NY P TYN PN DRSR - MTGEQ ----------- L R NR IMTD V FE PGS IM K 309
Cdd:TIGR03423 238 ------ Q AA EKALGGRR GA VV V M D P RTGE I LA M V ST P SFD PN LFVD g ISSKD ykallndpdrp L L NR AIQG V YP PGS TF K 311
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 310 P FTVSL AL DLHRV TP N T LV e TGN G H F V L D G APITDD -- A G F G TLTVGGV I QK S SNIGATKI A MTMRPEEMWNMYTSI G L G 387
Cdd:TIGR03423 312 P VVALA AL EEGVI TP E T RI - YCP G Y F Q L G G RRFRCW kr G G H G RVDLRKA I EE S CDVYFYQL A LRLGIDKIAEYAKRF G F G 390
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 388 Q APKVGF PG AVA G RL -- R P WK ------ S W RRIE qa T MSYGY G --- LS V SLF QLA R A YT A I A HD G E L MPVTIF K -- T DP N - 453
Cdd:TIGR03423 391 Q KTGIDL PG EKS G LV ps R E WK rkrfgq P W YPGD -- T LNVSI G qgy VL V TPL QLA V A TA A L A NG G K L YKPHLV K si E DP D g 468
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 454 ------- QPIAGTQVFN P TTARE VR - A M LET V VA PGGT SPD A AVP - G Y RVG GK S GTA ---------- Y KH E GHGYTRKYR 514
Cdd:TIGR03423 469 gvvrrte PEVLRPLPIS P ENLDV VR e G M RDV V NG PGGT ARR A RLG l P Y KMA GK T GTA qvvslkqgek Y DA E QIPERLRDH 548
570 580 590 600
....*....|....*....|....*....|....*....|.
gi 757910760 515 A S FV GM AP MP NP RVVI AV S V D ept A G SH f G GQVSG P VFSA I 555
Cdd:TIGR03423 549 A L FV AF AP YD NP KIAV AV I V E --- H G GG - G SSAAA P IARK I 585
Transpeptidase
pfam00905 Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ...
259-555
1.98e-72
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain]
Cd Length: 296
Bit Score: 234.62
E-value: 1.98e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 259 G A A M V V D VR TGEVLA L V NY P T Y N PN DR srmt GEQ LRNR IM T DVF EPGS IM KPFT VSL ALD LHRVT P NTLVETGN G HFV l D 338
Cdd:pfam00905 1 G S A V V L D PK TGEVLA M V GK P S Y D PN GF ---- IGP LRNR AV T SRY EPGS TF KPFT ALA ALD NGVLK P DETIFDWP G KQQ - G 75
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 339 G AP I ---- T D DA G F GTL T vg GVIQK SSN IGAT K I A MTMRPEEMWNMYTSI G L G QAPKV G F PG AV AG R L R P wk S W rr I E Q A 414
Cdd:pfam00905 76 G KS I gdwn Q D QV G I GTL R -- QALEY SSN WYMQ K L A QKLGADKLRSYLKKF G Y G NKTGI G L PG EN AG Y L T P -- Y W -- L E G A 149
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 415 T M S Y G Y GL SVSLF Q L A R AY T AIA HD G E L M P VTIF K TDP --- NQPIAGTQVFNPT TA RE V RA ML ET VV AP G GTSPD AAVPG 491
Cdd:pfam00905 150 T A S F G I GL TITPL Q Q A Q AY A AIA NG G K L V P PHLV K SIE dkv DPKVLNKLPISKS TA EK V KD ML RL VV ND G TGTGT AAVPG 229
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 757910760 492 Y R V G GK S GTA --- YKHE G HG Y TRKYRAS FVG M AP MP NP RVVI AV SV D E P TAG sh F GG Q V SG P V F SA I 555
Cdd:pfam00905 230 Y K V A GK T GTA qva GPKG G GY Y DGAQIGW FVG Y AP AD NP KYAF AV LI D D P KRY -- Y GG K V AA P I F KD I 294
MrcB
COG0744 Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ...
215-590
3.82e-31
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain]
Cd Length: 630
Bit Score: 128.50
E-value: 3.82e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 215 II E DVA E QIPPHN G TDVDLSI D S K I Q YI A YANL K AAVEKF K AKA -- G A AM VVD VR TGEVLA L V NYPT Y npndrsrmt G EQ 292
Cdd:COG0744 281 LE E LLG E DDLYRG G LKIYTTL D P K L Q KA A EKAV K NVLPEG K PGG lq A A LV VVD PK TGEVLA M V GGRD Y --------- G KS 351
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 293 LR NR IMTDVFE PGS IM KPF TVSL AL D l HRV TP N T L V ETGNGH F VLD G APIT -- D DAGF G TL T VGGVIQK S S N IG A TKI A M 370
Cdd:COG0744 352 QF NR ATQAKRQ PGS TF KPF VYAA AL E - QGY TP A T T V DDEPVT F PGG G WSPK ny D GRYR G PV T LREALAN S L N TP A VRL A Q 430
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 371 TMRPEEMWNMYTSI G L g QA P KVGF P GAVA G rlrpwkswrrieqatmsygy GLS VS LFQL A R AY TAI A HD G ELM - P VT I F K 449
Cdd:COG0744 431 EVGLDKVVDTARRL G I - TS P LDPN P SLAL G -------------------- TSE VS PLEM A S AY ATF A NG G VYV e P HA I T K 489
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 450 - TD PN ------ QPIAGT QV FN P TT A REVRA ML ET VV A p G GT SPD A AV PG YR V G GK S GT aykheghgy T RKY R AS - FVG M a 521
Cdd:COG0744 490 v TD AD gkvlye AKPKCE QV IS P EV A YLMTD ML QD VV T - S GT GRA A RL PG RP V A GK T GT --------- T NDN R DA w FVG Y - 558
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 757910760 522 pmp N P RV V I AV S V --- D EPTA G SHF GG QVSG P VFSAIAGDTMRA L N V PPNMPIKQL V VS D DSPES P AAKG P Q 590
Cdd:COG0744 559 --- T P QL V T AV W V gnd D NSPM G YVT GG SLPA P IWRDFMEAALEG L P V EDFPKPSGV V RI D EPSPT P SGTE P T 627
PRK10795
PRK10795 penicillin-binding protein 2; Provisional
56-570
1.38e-25
penicillin-binding protein 2; Provisional
Pssm-ID: 236761 [Multi-domain]
Cd Length: 634
Bit Score: 111.78
E-value: 1.38e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 56 YQ KQGESRYQRTIELPAT RG K I L DRNG LV LA TSLPVRAIWAI P DA V p D D L DA d KINQ L GKLLGM T SKEL --- R VKLSEDK 132
Cdd:PRK10795 51 YQ TRSNENRIKLVPIAPS RG I I Y DRNG TP LA LNRTIYQLEMM P EK V - D N L QQ - TLDA L RSVVDL T DDDI aaf R KERARSR 128
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 133 G F VYVKRQVPID --- VA D - K V AALDI PG I ---- YQR neyk R F YP E G EITA H L IG FT ------ N VE --------------- 183
Cdd:PRK10795 129 R F TSIPVKTNLT evq VA R f A V NQYRF PG V evkg YQR ---- R Y YP Y G SALT H V IG YV skindk D VE rldkegklanyaath 204
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 184 D E G QE G V E LGDQKM L S G TS G MRR V IKDRM G HI I EDVA EQ i PP HN G T D VD L SI D S K I Q - YI ayanlkaav E KFK A KAG AA M 262
Cdd:PRK10795 205 D I G KL G I E RYYEDV L H G KT G YEE V EVNNR G RV I RQLH EQ - PP QA G H D IY L TL D L K L Q q YI --------- E TLL A GSR AA V 274
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 263 VV - D V RTG EV LALV NY P T Y N PN --------- D R S RMTGEQL R --- NR IMTD V FE P G S IM KP FTVSL AL DLHRV T P NT - L V 328
Cdd:PRK10795 275 VV t D P RTG GI LALV ST P S Y D PN lfvdgissk D Y S GLLNDPN R pli NR ATQG V YP P A S TV KP YVAVS AL SAGVI T R NT s L F 354
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 329 ET G NGHFVLDGAPIT D -- DA G F G T L T V GGVIQK S SNIGATKI A MT M RPEEMWNMYTSI G L G QAPKVGFPGAVA G RL -- R P 404
Cdd:PRK10795 355 DP G WWQLPGSEKRYR D wk KW G H G R L N V TKSLEE S ADTFFYQV A YD M GIDRLSEWMGKF G Y G HYTGIDLAEERS G NM pt R E 434
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 405 WK S w R R IEQA ----- T MSY G Y G --- LSVSLF Q LAR A YTAIAH DG E ----- L MPV T I ------- FKTDPNQ P IAGTQVFNP 464
Cdd:PRK10795 435 WK Q - K R FKKP wyqgd T IPV G I G qgy WTATPI Q MSK A LMTLIN DG I vkvph L LMS T A edgkqvp WVQPHEP P VGDIHSGYW 513
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 465 TT A RE vr A M LETVVA P G GT SPD -- A AV P g Y RVGG KSGTA YKH e G HGYTRK Y R A S ----------- FVGM AP MP NP R V VI A 531
Cdd:PRK10795 514 EI A KD -- G M YGVANR P N GT AHK yf A SA P - Y KIAA KSGTA QVF - G LKANET Y N A H kiaerlrdhkl MTAF AP YN NP Q V AV A 589
570 580 590
....*....|....*....|....*....|....*....
gi 757910760 532 VSVDEPT AG SHF G GQVSGPVFSAIA GD TMRA L NVPPNMP 570
Cdd:PRK10795 590 IILENGG AG PAV G TIMRQILDHIML GD NNTD L PAENPAV 628
PBP_dimer
pfam03717 Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of ...
70-217
6.29e-22
Penicillin-binding Protein dimerization domain; This domain is found at the N terminus of Class B High Molecular Weight Penicillin-Binding Proteins. Its function has not been precisely defined, but is strongly implicated in PBP polymerization. The domain forms a largely disordered 'sugar tongs' structure.
Pssm-ID: 427460 [Multi-domain]
Cd Length: 178
Bit Score: 93.16
E-value: 6.29e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 70 L PA T RG K I L DRNG L VLAT SL PV RAIWAI P DAVPDDLDADKINQ L G KLL G ---- MTSKE L RVKLSEDKGF ----- V YV K RQ 140
Cdd:pfam03717 2 I PA P RG E I Y DRNG V VLAT NK PV YSLTIT P SKLKKADALKTALK L A KLL S nyed LDDED L TERFLKMNSY ksyyp V VI K KN 81
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 141 VPIDVADKVA -- A L DI PG IYQRNEYK R F YP E GE IT AHL I G FTNVED E ----------------- G QE G V E LGDQKM L S G T 201
Cdd:pfam03717 82 LSEEEVARIE en L L EL PG VSIETDPV R Y YP Y GE LA AHL L G YVGEIT E eelekyldkgysrgdlv G KS G L E KQYESV L R G K 161
170
....*....|....*.
gi 757910760 202 S G M R R V IK D RM G HI I E 217
Cdd:pfam03717 162 D G V R Q V EV D AL G RV I R 177
PBP_1c
TIGR02073 penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ...
214-594
4.71e-21
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain]
Cd Length: 727
Bit Score: 97.88
E-value: 4.71e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 214 H IIEDVAEQI P PHNGT d VDLSI D SKI Q YIAYANLKAAVEKFKAKA --- G A AM VVD V R T G E VLA L V NYPTYNPNDR S RMTG 290
Cdd:TIGR02073 228 H FALKLLRAR P EIASV - IVSTL D ADL Q RRLEELARRYLSALRPRG isn L A IL VVD N R S G A VLA Y V GSADFFDDSN S GQVD 306
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 291 EQLRN R imtdvf E PGS IM KPF TVS LALD LHRVT P NT L ----- VET G nghfvl D G AP ITD D AG F - G TLTVGGVIQK S S NI G 364
Cdd:TIGR02073 307 GVRAP R ------ S PGS TL KPF LYA LALD DGLLH P DS L lkdvp LRF G ------ D Y AP ENF D KT F h G PVPAREALAR S L NI P 374
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 365 A TK iamtmrpeemwnmytsiglgqapkvgfpga VAG R LR P WKSWRRIE QA TM ------ S YG YGLS ------- VS L FQ LA R 431
Cdd:TIGR02073 375 A VR ------------------------------ LLE R VG P PRFADFLR QA GL nllkpk S DY YGLS lalggae IT L QD LA N 424
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 432 A Y TAI A HD G ELM P VTIFK TD PNQ P IA g TQVFN P TT A RE V RAM L ETVVA P GG T S P DA A V P - GYRVGG K S GT A Y khegh G YT 510
Cdd:TIGR02073 425 L Y AML A NQ G LSG P LRFLQ TD AKR P ER - ERLLS P GA A WI V LDI L KDRPR P DD T L P LS A L P t RLPLAW K T GT S Y ----- G FR 498
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 511 RKYR A SF vgmapmp NP R VV I A V S V DEPTAGSH --- FG GQVSG P VFSA I AGDT - MRALNVP P N m P I K QLVVSDDSPES P AA 586
Cdd:TIGR02073 499 DAWA A GV ------- SG R YT I G V W V GNFDGKPN pgf FG AAAAA P LLFD I LDAL q ASEASTL P R - P L K EVPGCLVLGNL P IL 570
....*...
gi 757910760 587 KG P QKLAA 594
Cdd:TIGR02073 571 PC P EQIST 578
PbpC
COG4953 Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ...
214-552
7.92e-20
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain]
Cd Length: 773
Bit Score: 93.74
E-value: 7.92e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 214 H IIEDVAE Q I P ph N GT DVDLSI D SKI Q YIAYANLKAA V EKF K AKA --- G A AM VVD V RTGEVLA L V NYPTYN pn D R SR --- 287
Cdd:COG4953 259 H LARRLLR Q L P -- G GT RIRTTL D AGL Q RRLERLVRRY V RRL K QNG ihn A A VL VVD N RTGEVLA Y V GSADFF -- D A SR qgq 334
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 288 -- M T g EQ LR N rimtdvfe PGS IM KPF TVS LALD LHRVT P N TL VE --- T GN G HF vldg A P ITD D AG F - G TLTVGGVIQK S S 361
Cdd:COG4953 335 vd M V - RA LR S -------- PGS TL KPF LYG LALD QGLIH P E TL LA dvp T SF G GY ---- R P ENF D GT F q G PVSAREALAR S L 401
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 362 NI G A TKIAMTMR P EEMWNM ytsig L GQ A pkv G FPG avag R L R P WKS wrrieqatmsyg YGLS ------- V S L FQ L ARA Y T 434
Cdd:COG4953 402 NI P A VRLLEALG P ARFYAR ----- L RR A --- G LRL ---- L L P P AEH ------------ YGLS lilggae V T L EE L VGL Y A 457
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 435 A I A HD GE LM P VTIFKTD P NQ P ia G TQVFN P TT A RE VR AM L ET V VA P G G TSPDA A VP - GYRVGG K S GT A Y khe G H ------ 507
Cdd:COG4953 458 A L A RG GE AR P LRLLAGE P AS P -- G RRLLS P GA A WL VR DI L SD V PR P D G AFGWR A LD s PPPIAW K T GT S Y --- G F rdawav 532
330 340 350 360
....*....|....*....|....*....|....*....|....*....
gi 757910760 508 G Y T RK Y rasfvgmapmpnprv VIA V S V --- D - E P TA G s HF G GQVSG P VF 552
Cdd:COG4953 533 G F T GR Y --------------- TVG V W V gnp D g T P VP G - LT G AEAAA P LL 565
PBP_1a_fam
TIGR02074 penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ...
215-555
1.49e-19
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain]
Cd Length: 531
Bit Score: 92.32
E-value: 1.49e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 215 I I EDVA E QIPPH --- N G TDVDLSI D SKI Q YI A YAN L KAAVEKFKAKA G ----- A AMVV D VR TG E V L ALV NYPT Y NPNDRS 286
Cdd:TIGR02074 205 V I QELE E EYGEE lyt G G LKIYTTL D LDA Q KA A EKV L NTGLRVAGRRD G ddlqa A LVAI D PD TG A V R ALV GGRD Y GKSQFN 284
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 287 R M T g EQL R nrimtdvf E PGS IM KPF TVSL AL DL h RV TP N T L V E ------ T GNG HF vldg A P ITDDA G F - G TL T VGGVIQK 359
Cdd:TIGR02074 285 R A T - QAK R -------- Q PGS TF KPF VYAA AL EK - GL TP A T I V N depity N GNG PW ---- S P KNYGG G Y r G NV T LRQALAQ 350
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 360 S S NI G A TKIAM tmrpeemwnmytsiglgqap K VG FPGA VA grlrpwk SWR R I ----- EQATM S YGY G - LS VS LFQL A R AY 433
Cdd:TIGR02074 351 S R NI P A VRLLQ -------------------- E VG LDKV VA ------- LAK R F gitsp LDPVL S LAL G t VE VS PLEM A S AY 403
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 757910760 434 TAI A HD G - ELM P VT I F K - T D PNQPI ------ AG TQV FN P T TA REVRA ML ET VV A p G GT SPD A AV PG YR V G GK S GT aykhe 505
Cdd:TIGR02074 404 AVF A NG G k YVE P HG I R K i V D RDGKV iyenkp KT TQV IS P A TA YIMTD ML KG VV E - S GT GRS A RL PG RP V A GK T GT ----- 477
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*
gi 757910760 506 ghgy T RKY R - A S FVG M apmp N P RV V I AV S V --- D EP T A G SHF - GG QVSG P VFSAI 555
Cdd:TIGR02074 478 ---- T QNW R d A W FVG Y ---- T P YY V T AV W V gyd D KK T L G KSG t GG GLAA P IWRDF 524
Blast search parameters
Data Source:
Precalculated data, version = cdd.v.3.21
Preset Options: Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
