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Conserved domains on  [gi|756978273|ref|WP_042666366|]
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nucleotide sugar dehydrogenase [Haloferax sp. ATB1]

Protein Classification

nucleotide sugar dehydrogenase( domain architecture ID 11430796)

nucleotide sugar dehydrogenase such as UDP-N-acetylglucosamine 6-dehydrogenase, which catalyzes the C-6 dehydrogenation of UDP-D-GlcNAc to UDP-N-acetylglucosaminuronic acid (UDP-D-GlcNAcA)

CATH:  3.40.50.720
EC:  1.1.1.-
Gene Ontology:  GO:0051287|GO:0016628

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
WecC COG0677
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];
31-443 4.21e-161

UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 440441 [Multi-domain]  Cd Length: 413  Bit Score: 461.45  E-value: 4.21e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIvGEPGlDELVEELVEDGALVANTEPREVADeASIHV 110
Cdd:COG0677    2 IAVIGLGYVGLPLAVAFAKAGFRVIGFDINPERVEELNAGEDPI-LEPG-DELLAEAVAAGRLRATTDPEALAE-ADVVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGE-FGLAFCPERTSSGRA 189
Cdd:COG0677   79 IAVPTPLDEDKEPDLSYLESASETIAPHLKPGDLVVLESTVYPGTTEEVCVPILEKRSGLKAGEdFFLAYSPERINPGNK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 190 LKDIRgAYPKVVGGADDESTRAASLIYDQISSNEVITVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAI 269
Cdd:COG0677  159 LHELR-NIPKVVGGITPESAERAAALYGSVVTAGVVPVSSIKVAEAAKLIENTYRDVNIALANELALICDRLGIDVWEVI 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 270 DVANTQPFCEIHTPGAGVGGHCIPYYPQFLITQFETG---SPLMETARAVNDEMPHVTAQTALDRLAARGIDPEDATVLV 346
Cdd:COG0677  238 EAANTKPGFLIFYPGPGVGGHCIPVDPYYLTWKARELgyhPRLILAAREINDSMPEYVVERVVKALNEAGKSLKGARVLV 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 347 LGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVmrgvtsdDLSP-----DAIVLVTAHESFD 421
Cdd:COG0677  318 LGLAYKENVDDLRESPALDIIEELREYGAEVDVHDPYVDEEEVEGEYGELV-------DLEEalegaDAVVLAVDHDEFD 390

                        410       420
                 ....*....|....*....|..
gi 756978273 422 HLDVPAFADDDRPVVfVDGRQA 443
Cdd:COG0677  391 ELDPEELRLKGAKVV-VDTRGV 411
 
Name Accession Description Interval E-value
WecC COG0677
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];
31-443 4.21e-161

UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440441 [Multi-domain]  Cd Length: 413  Bit Score: 461.45  E-value: 4.21e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIvGEPGlDELVEELVEDGALVANTEPREVADeASIHV 110
Cdd:COG0677    2 IAVIGLGYVGLPLAVAFAKAGFRVIGFDINPERVEELNAGEDPI-LEPG-DELLAEAVAAGRLRATTDPEALAE-ADVVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGE-FGLAFCPERTSSGRA 189
Cdd:COG0677   79 IAVPTPLDEDKEPDLSYLESASETIAPHLKPGDLVVLESTVYPGTTEEVCVPILEKRSGLKAGEdFFLAYSPERINPGNK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 190 LKDIRgAYPKVVGGADDESTRAASLIYDQISSNEVITVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAI 269
Cdd:COG0677  159 LHELR-NIPKVVGGITPESAERAAALYGSVVTAGVVPVSSIKVAEAAKLIENTYRDVNIALANELALICDRLGIDVWEVI 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 270 DVANTQPFCEIHTPGAGVGGHCIPYYPQFLITQFETG---SPLMETARAVNDEMPHVTAQTALDRLAARGIDPEDATVLV 346
Cdd:COG0677  238 EAANTKPGFLIFYPGPGVGGHCIPVDPYYLTWKARELgyhPRLILAAREINDSMPEYVVERVVKALNEAGKSLKGARVLV 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 347 LGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVmrgvtsdDLSP-----DAIVLVTAHESFD 421
Cdd:COG0677  318 LGLAYKENVDDLRESPALDIIEELREYGAEVDVHDPYVDEEEVEGEYGELV-------DLEEalegaDAVVLAVDHDEFD 390

                        410       420
                 ....*....|....*....|..
gi 756978273 422 HLDVPAFADDDRPVVfVDGRQA 443
Cdd:COG0677  391 ELDPEELRLKGAKVV-VDTRGV 411
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 31-442 8.86e-116

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 345.75  E-value: 8.86e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVEDGALVANTEPREVADEASIHV 110
Cdd:TIGR03026   3 IAVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIY-EPGLDELLAKALKAGRLRATTDYEEAIRDADVII 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESeSGLSLGE-FGLAFCPERTSSGRA 189
Cdd:TIGR03026  82 ICVPTPLKEDGSPDLSYVESAAETIAKHLRKGATVVLESTVPPGTTEEVVKPILER-SGLKLGEdFYLAYNPEFLREGNA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  190 LKDIRGAyPKVVGGADDESTRAASLIYDQISSNEVItVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAI 269
Cdd:TIGR03026 161 VHDLLHP-DRIVGGETEEAGEAVAELYSPIIDGPVL-VTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVYEVI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  270 DVANTQPF--CEIHTPGAGVGGHCIPYYPQFLITQF-ETG--SPLMETARAVNDEMPHVTAQTALDRLaargIDPEDATV 344
Cdd:TIGR03026 239 EAAGTDPRigFNFLNPGPGVGGHCIPKDPLALIAKAkELGynPELIEAAREINDSQPDYVVEKIKDLL----GPLKGKTV 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  345 LVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVMRGVTSDdlsPDAIVLVTAHESFDHLD 424
Cdd:TIGR03026 315 LILGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLPSIDDLEEALKG---ADALVILTDHSEFKDLD 391

                         410
                  ....*....|....*....
gi 756978273  425 VPAFAD-DDRPVVfVDGRQ 442
Cdd:TIGR03026 392 LEKIKDlMKGKVV-VDTRN 409
wecC PRK11064
UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional
 31-382 3.39e-65

UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional


Pssm-ID: 182940 [Multi-domain]  Cd Length: 415  Bit Score: 215.62  E-value: 3.39e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVEDGALVANTEPrevaDEASIHV 110
Cdd:PRK11064   6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIV-EPDLDMVVKTAVEGGYLRATTTP----EPADAFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSL----GE---FGLAFCPER 183
Cdd:PRK11064  81 IAVPTPFKGDHEPDLTYVEAAAKSIAPVLKKGDLVILESTSPVGATEQMAEWLAEARPDLTFpqqaGEqadINIAYCPER 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 184 TSSGRALKDIRgAYPKVVGGADDESTRAASLIYDQISSNEVItVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEI 263
Cdd:PRK11064 161 VLPGQVMVELI-KNDRVIGGMTPVCSARASELYKIFLEGECV-VTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 264 DVTEAIDVANTQPFCEIHTPGAGVGGHCIPYYPQFLITQFETGSPLMETARAVNDEMPH-----VTAQTAlDRLAARGID 338
Cdd:PRK11064 239 NVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDGKPHwvidqVKAAVA-DCLAATDKR 317

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 756978273 339 PEDATVLVLGLTYRAGVEEIRKTPALPVVEHL-DEAGADVVATDP 382
Cdd:PRK11064 318 ASEVKIACFGLAFKPNIDDLRESPAMEIAELIaQWHSGETLVVEP 362
UDPG_MGDP_dh_N pfam03721
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ...
 31-212 4.53e-41

UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 397677 [Multi-domain]  Cd Length: 186  Bit Score: 144.70  E-value: 4.53e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVeDGALVANTEPREVADEASIHV 110
Cdd:pfam03721   3 ISVIGLGYVGLPTAACLAEIGHDVIGVDIDEEKVDKLNSGQIPIY-EPGLDELVKANV-SGRLSFTTDYSTAIEEADVIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  111 VIVPTLVDEAGR-PDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGEFGLAFCPERTSSGRA 189
Cdd:pfam03721  81 IAVGTPSKKGGGaADLKYVESAARSIAPHLKKGKVVVVKSTVPVGTTENLVKPIIEEGGKKVGVDFDVASNPEFLREGSA 160

                         170       180
                  ....*....|....*....|...
gi 756978273  190 LKDIRGAyPKVVGGADDESTRAA 212
Cdd:pfam03721 161 VYDLFNP-DRVVIGVTEKCAEAA 182
UDPG_MGDP_dh_C smart00984
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ...
 345-441 3.22e-15

UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 214954 [Multi-domain]  Cd Length: 99  Bit Score: 71.00  E-value: 3.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   345 LVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDtaVFEEAGATVMRGVTSDDLSPDAIVLVTAHESFDHLD 424
Cdd:smart00984   1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYDPYAME--EAREYGLTYVSDLEEALKGADAVVIATEHDEFRSLD 78

                           90
                   ....*....|....*..
gi 756978273   425 VPAFADDDRPVVFVDGR 441
Cdd:smart00984  79 PEELKDLMKKPVVVDGR 95
 
Name Accession Description Interval E-value
WecC COG0677
UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];
31-443 4.21e-161

UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440441 [Multi-domain]  Cd Length: 413  Bit Score: 461.45  E-value: 4.21e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIvGEPGlDELVEELVEDGALVANTEPREVADeASIHV 110
Cdd:COG0677    2 IAVIGLGYVGLPLAVAFAKAGFRVIGFDINPERVEELNAGEDPI-LEPG-DELLAEAVAAGRLRATTDPEALAE-ADVVI 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGE-FGLAFCPERTSSGRA 189
Cdd:COG0677   79 IAVPTPLDEDKEPDLSYLESASETIAPHLKPGDLVVLESTVYPGTTEEVCVPILEKRSGLKAGEdFFLAYSPERINPGNK 158

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 190 LKDIRgAYPKVVGGADDESTRAASLIYDQISSNEVITVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAI 269
Cdd:COG0677  159 LHELR-NIPKVVGGITPESAERAAALYGSVVTAGVVPVSSIKVAEAAKLIENTYRDVNIALANELALICDRLGIDVWEVI 237

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 270 DVANTQPFCEIHTPGAGVGGHCIPYYPQFLITQFETG---SPLMETARAVNDEMPHVTAQTALDRLAARGIDPEDATVLV 346
Cdd:COG0677  238 EAANTKPGFLIFYPGPGVGGHCIPVDPYYLTWKARELgyhPRLILAAREINDSMPEYVVERVVKALNEAGKSLKGARVLV 317

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 347 LGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVmrgvtsdDLSP-----DAIVLVTAHESFD 421
Cdd:COG0677  318 LGLAYKENVDDLRESPALDIIEELREYGAEVDVHDPYVDEEEVEGEYGELV-------DLEEalegaDAVVLAVDHDEFD 390

                        410       420
                 ....*....|....*....|..
gi 756978273 422 HLDVPAFADDDRPVVfVDGRQA 443
Cdd:COG0677  391 ELDPEELRLKGAKVV-VDTRGV 411
NDP-sugDHase TIGR03026
nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent ...
 31-442 8.86e-116

nucleotide sugar dehydrogenase; Enzymes in this family catalyze the NAD-dependent alcohol-to-acid oxidation of nucleotide-linked sugars. Examples include UDP-glucose 6-dehydrogenase (1.1.1.22), GDP-mannose 6-dehydrogenase (1.1.1.132), UDP-N-acetylglucosamine 6-dehydrogenase (1.1.1.136), UDP-N-acetyl-D-galactosaminuronic acid dehydrogenase, and UDP-N-acetyl-D-mannosaminuronic acid dehydrogenase. These enzymes are most often involved in the biosynthesis of polysaccharides and are often found in operons devoted to that purpose. All of these enzymes contain three Pfam domains, pfam03721, pfam00984, and pfam03720 for the N-terminal, central, and C-terminal regions respectively.


Pssm-ID: 274399 [Multi-domain]  Cd Length: 409  Bit Score: 345.75  E-value: 8.86e-116
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVEDGALVANTEPREVADEASIHV 110
Cdd:TIGR03026   3 IAVIGLGYVGLPLAALLADLGHDVTGVDIDQEKVDKLNKGKSPIY-EPGLDELLAKALKAGRLRATTDYEEAIRDADVII 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESeSGLSLGE-FGLAFCPERTSSGRA 189
Cdd:TIGR03026  82 ICVPTPLKEDGSPDLSYVESAAETIAKHLRKGATVVLESTVPPGTTEEVVKPILER-SGLKLGEdFYLAYNPEFLREGNA 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  190 LKDIRGAyPKVVGGADDESTRAASLIYDQISSNEVItVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAI 269
Cdd:TIGR03026 161 VHDLLHP-DRIVGGETEEAGEAVAELYSPIIDGPVL-VTSIETAEMIKLAENTFRAVKIAFANELARICEALGIDVYEVI 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  270 DVANTQPF--CEIHTPGAGVGGHCIPYYPQFLITQF-ETG--SPLMETARAVNDEMPHVTAQTALDRLaargIDPEDATV 344
Cdd:TIGR03026 239 EAAGTDPRigFNFLNPGPGVGGHCIPKDPLALIAKAkELGynPELIEAAREINDSQPDYVVEKIKDLL----GPLKGKTV 314

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  345 LVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVMRGVTSDdlsPDAIVLVTAHESFDHLD 424
Cdd:TIGR03026 315 LILGLAFKPNTDDVRESPALDIIELLKEKGAKVKAYDPLVPEEEVKGLPSIDDLEEALKG---ADALVILTDHSEFKDLD 391

                         410
                  ....*....|....*....
gi 756978273  425 VPAFAD-DDRPVVfVDGRQ 442
Cdd:TIGR03026 392 LEKIKDlMKGKVV-VDTRN 409
wecC PRK11064
UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional
 31-382 3.39e-65

UDP-N-acetyl-D-mannosamine dehydrogenase; Provisional


Pssm-ID: 182940 [Multi-domain]  Cd Length: 415  Bit Score: 215.62  E-value: 3.39e-65
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVEDGALVANTEPrevaDEASIHV 110
Cdd:PRK11064   6 ISVIGLGYIGLPTAAAFASRQKQVIGVDINQHAVDTINRGEIHIV-EPDLDMVVKTAVEGGYLRATTTP----EPADAFL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSL----GE---FGLAFCPER 183
Cdd:PRK11064  81 IAVPTPFKGDHEPDLTYVEAAAKSIAPVLKKGDLVILESTSPVGATEQMAEWLAEARPDLTFpqqaGEqadINIAYCPER 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 184 TSSGRALKDIRgAYPKVVGGADDESTRAASLIYDQISSNEVItVSDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEI 263
Cdd:PRK11064 161 VLPGQVMVELI-KNDRVIGGMTPVCSARASELYKIFLEGECV-VTNSRTAEMCKLTENSFRDVNIAFANELSLICADQGI 238

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 264 DVTEAIDVANTQPFCEIHTPGAGVGGHCIPYYPQFLITQFETGSPLMETARAVNDEMPH-----VTAQTAlDRLAARGID 338
Cdd:PRK11064 239 NVWELIRLANRHPRVNILQPGPGVGGHCIAVDPWFIVAQNPQQARLIRTAREVNDGKPHwvidqVKAAVA-DCLAATDKR 317

                        330       340       350       360
                 ....*....|....*....|....*....|....*....|....*
gi 756978273 339 PEDATVLVLGLTYRAGVEEIRKTPALPVVEHL-DEAGADVVATDP 382
Cdd:PRK11064 318 ASEVKIACFGLAFKPNIDDLRESPAMEIAELIaQWHSGETLVVEP 362
Ugd COG1004
UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];
31-459 5.85e-50

UDP-glucose 6-dehydrogenase [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440628 [Multi-domain]  Cd Length: 436  Bit Score: 175.60  E-value: 5.85e-50
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVEDGALVANTEPREVADEASIHV 110
Cdd:COG1004    3 IAVIGTGYVGLVTAACLAELGHEVTCVDIDEEKIEALNAGEIPIY-EPGLEELVARNVAAGRLRFTTDLAEAVAEADVVF 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 111 VIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCrDALLPLLESESGLSLGEFGLAFCPERTSSGRAL 190
Cdd:COG1004   82 IAVGTPSDEDGSADLSYVLAAARSIGEALKGYKVVVTKSTVPVGTA-DRVRAIIAEELRGAGVDFDVVSNPEFLREGSAV 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 191 KDIRgaYP-KVVGGADDEstRAASL---IYDQISSNEV-ITVSDTTTAEAVKVfegvyrDVN------IALANELATHAG 259
Cdd:COG1004  161 EDFL--RPdRIVIGVDSE--RAAEVlreLYAPFVRNGTpIIVTDLRSAELIKY------AANaflatkISFINEIANLCE 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 260 EFEIDVTEaidVANTqpfceIHT----------PGAGVGGHCIPYYPQFLI---TQFETGSPLMETARAVNDEMPHVTAQ 326
Cdd:COG1004  231 KVGADVEE---VARG-----IGLdsrigpkflyAGIGYGGSCFPKDVRALIataRELGYDLRLLEAVEEVNERQKRRLVE 302

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 327 TALDRLaarGIDPEDATVLVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDP--------ILDDTAVFEEAGATVM 398
Cdd:COG1004  303 KIREHL---GGDLKGKTIAVLGLAFKPNTDDMRESPALDIIEALLEAGARVRAYDPvamenarrLLPDDITYADDAYEAL 379

                        410       420       430       440       450       460
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 756978273 399 RGVtsddlspDAIVLVTAHESFDHLDVPAFADDDRPVVFVDGRQAateYrDHDRV-----DYEGIG 459
Cdd:COG1004  380 EGA-------DALVILTEWPEFRALDFARLKALMKGPVIFDGRNL---L-DPEELraagfTYYGIG 434
PRK15182 PRK15182
Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB;
24-431 3.53e-45

Vi polysaccharide biosynthesis UDP-N-acetylglucosamine C-6 dehydrogenase TviB;


Pssm-ID: 185104 [Multi-domain]  Cd Length: 425  Bit Score: 162.93  E-value: 3.53e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  24 FTSGDVPVGVYGLGKMGLPLASVYAETTgNVTGADIDTDVVREINAGRnhivgEPGLDELVEELVEDGALVANTEPREVa 103
Cdd:PRK15182   2 FGIDEVKIAIIGLGYVGLPLAVEFGKSR-QVVGFDVNKKRILELKNGV-----DVNLETTEEELREARYLKFTSEIEKI- 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 104 DEASIHVVIVPTLVDEAGRPDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGE-FGLAFCPE 182
Cdd:PRK15182  75 KECNFYIITVPTPINTYKQPDLTPLIKASETVGTVLNRGDIVVYESTVYPGCTEEECVPILARMSGMTFNQdFYVGYSPE 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 183 RTSSG---RALKDIRgaypKVVGGADDESTRAASLIYDQISSNEVITVSDTTTAEAVKVFEGVYRDVNIALANELATHAG 259
Cdd:PRK15182 155 RINPGdkkHRLTNIK----KITSGSTAQIAELIDEVYQQIISAGTYKAESIKVAEAAKVIENTQRDLNIALVNELAIIFN 230

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 260 EFEIDVTEAIDVANTQ----PFceihTPGAgVGGHCI---PYYPQFLITQFETGSPLMETARAVNDEMPHVTAQTALDRL 332
Cdd:PRK15182 231 RLNIDTEAVLRAAGSKwnflPF----RPGL-VGGHCIgvdPYYLTHKSQGIGYYPEIILAGRRLNDNMGNYVSEQLIKAM 305

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 333 AARGIDPEDATVLVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAGATVMRGVTSDDLspDAIV 412
Cdd:PRK15182 306 IKKGINVEGSSVLILGFTFKENCPDIRNTRIIDVVKELGKYSCKVDIFDPWVDAEEVRREYGIIPVSEVKSSHY--DAII 383

                        410       420
                 ....*....|....*....|..
gi 756978273 413 LVTAHESFDHL---DVPAFADD 431
Cdd:PRK15182 384 VAVGHQQFKQMgseDIRGFGKD 405
UDPG_MGDP_dh_N pfam03721
UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose ...
 31-212 4.53e-41

UDP-glucose/GDP-mannose dehydrogenase family, NAD binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 397677 [Multi-domain]  Cd Length: 186  Bit Score: 144.70  E-value: 4.53e-41
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRNHIVgEPGLDELVEELVeDGALVANTEPREVADEASIHV 110
Cdd:pfam03721   3 ISVIGLGYVGLPTAACLAEIGHDVIGVDIDEEKVDKLNSGQIPIY-EPGLDELVKANV-SGRLSFTTDYSTAIEEADVIF 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  111 VIVPTLVDEAGR-PDLSVIEAVARDIAKGLDEGDLVVFESTLPPRSCRDALLPLLESESGLSLGEFGLAFCPERTSSGRA 189
Cdd:pfam03721  81 IAVGTPSKKGGGaADLKYVESAARSIAPHLKKGKVVVVKSTVPVGTTENLVKPIIEEGGKKVGVDFDVASNPEFLREGSA 160

                         170       180
                  ....*....|....*....|...
gi 756978273  190 LKDIRGAyPKVVGGADDESTRAA 212
Cdd:pfam03721 161 VYDLFNP-DRVVIGVTEKCAEAA 182
UDPG_MGDP_dh pfam00984
UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose ...
 232-318 4.37e-25

UDP-glucose/GDP-mannose dehydrogenase family, central domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 460015 [Multi-domain]  Cd Length: 92  Bit Score: 98.60  E-value: 4.37e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  232 TAEAVKVFEGVYRDVNIALANELATHAGEFEIDVTEAIDVANTQPF--CEIHTPGAGVGGHCIPYYPQFLITQFET---G 306
Cdd:pfam00984   1 SAELIKLAENAFLAVKISFINELANLCEALGADVWEVIEAAGTDPRigPKFLYPGPGVGGSCLPKDPRALIYLARElgvP 80

                          90
                  ....*....|..
gi 756978273  307 SPLMETARAVND 318
Cdd:pfam00984  81 ARLLEAAREVNE 92
UDPG_MGDP_dh_C pfam03720
UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose ...
 345-441 8.31e-17

UDP-glucose/GDP-mannose dehydrogenase family, UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenaseses are a small group of enzymes which possesses the ability to catalyze the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 427462 [Multi-domain]  Cd Length: 103  Bit Score: 75.69  E-value: 8.31e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  345 LVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVFEEAgatvMRGVTSDDL-----SPDAIVLVTAHES 419
Cdd:pfam03720   1 AVLGLAFKPNTDDLRESPALDIIELLLEEGAEVKVYDPYVPEEAIEALG----DGVTLVDDLeealkGADAIVILTDHDE 76

                          90       100
                  ....*....|....*....|..
gi 756978273  420 FDHLDVPAFADDDRPVVFVDGR 441
Cdd:pfam03720  77 FKSLDWEKLKKLMKPPVVFDGR 98
UDPG_MGDP_dh_C smart00984
UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes ...
 345-441 3.22e-15

UDP binding domain; The UDP-glucose/GDP-mannose dehydrogenases are a small group of enzymes which possesses the ability to catalyse the NAD-dependent 2-fold oxidation of an alcohol to an acid without the release of an aldehyde intermediate.


Pssm-ID: 214954 [Multi-domain]  Cd Length: 99  Bit Score: 71.00  E-value: 3.22e-15
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   345 LVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDtaVFEEAGATVMRGVTSDDLSPDAIVLVTAHESFDHLD 424
Cdd:smart00984   1 AVLGLAFKPNTDDLRESPALDIIEELLEAGAEVVVYDPYAME--EAREYGLTYVSDLEEALKGADAVVIATEHDEFRSLD 78

                           90
                   ....*....|....*..
gi 756978273   425 VPAFADDDRPVVFVDGR 441
Cdd:smart00984  79 PEELKDLMKKPVVVDGR 95
PRK15057 PRK15057
UDP-glucose 6-dehydrogenase; Provisional
 31-390 9.26e-13

UDP-glucose 6-dehydrogenase; Provisional


Pssm-ID: 185017 [Multi-domain]  Cd Length: 388  Bit Score: 69.67  E-value: 9.26e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTgNVTGADIDTDVVREINagrNHIvgEPGLDELVEELVEDGAL--VANTEPREVADEASI 108
Cdd:PRK15057   3 ITISGTGYVGLSNGLLIAQNH-EVVALDILPSRVAMLN---DRI--SPIVDKEIQQFLQSDKIhfNATLDKNEAYRDADY 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 109 HVVIVPTLVD-EAGRPDLSVIEAVARDIAKgLDEGDLVVFESTLPPrSCRDALLPLLESESglslgefgLAFCPERTSSG 187
Cdd:PRK15057  77 VIIATPTDYDpKTNYFNTSSVESVIKDVVE-INPYAVMVIKSTVPV-GFTAAMHKKYRTEN--------IIFSPEFLREG 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 188 RALKDirGAYPK--VVGGADDESTRAASLIYDQISSNEVITV-SDTTTAEAVKVFEGVYRDVNIALANELATHAGEFEID 264
Cdd:PRK15057 147 KALYD--NLHPSriVIGERSERAERFAALLQEGAIKQNIPTLfTDSTEAEAIKLFANTYLAMRVAYFNELDSYAESLGLN 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 265 VTEAIDVANTQPFCEIH--TPGAGVGGHCIPYYPQFLITQFETG-----SPLMETARAVNDemphVTAQTALDRlaargi 337
Cdd:PRK15057 225 TRQIIEGVCLDPRIGNHynNPSFGYGGYCLPKDTKQLLANYQSVpnnliSAIVDANRTRKD----FIADAILSR------ 294

                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|...
gi 756978273 338 dpEDATVLVLGLTYRAGVEEIRKTPALPVVEHLDEAGADVVATDPILDDTAVF 390
Cdd:PRK15057 295 --KPQVVGIYRLIMKSGSDNFRASSIQGIMKRIKAKGVEVIIYEPVMKEDSFF 345
NAD_binding_2 pfam03446
NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of ...
 31-146 4.84e-05

NAD binding domain of 6-phosphogluconate dehydrogenase; The NAD binding domain of 6-phosphogluconate dehydrogenase adopts a Rossmann fold.


Pssm-ID: 427298 [Multi-domain]  Cd Length: 159  Bit Score: 43.61  E-value: 4.84e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273   31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVvreinagrnhivgepgldelVEELVEDGALVANTePREVADEASIHV 110
Cdd:pfam03446   2 IGFIGLGVMGSPMALNLLKAGYTVTVYNRTPEK--------------------VEELVAAGAIAAAS-PAEFVAGLDVVI 60

                          90       100       110
                  ....*....|....*....|....*....|....*.
gi 756978273  111 VIVPtlvdeAGRPDLSVIEavARDIAKGLDEGDLVV 146
Cdd:pfam03446  61 TMVP-----AGAAVDAVIF--GEGLLPGLKPGDIII 89
MmsB COG2084
3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport ...
 30-159 3.71e-04

3-hydroxyisobutyrate dehydrogenase or related beta-hydroxyacid dehydrogenase [Lipid transport and metabolism];


Pssm-ID: 441687 [Multi-domain]  Cd Length: 285  Bit Score: 42.41  E-value: 3.71e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  30 PVGVYGLGKMGLPLASVYAETTGNVTGADIDTDVvreinagrnhivgepgldelVEELVEDGALVANTePREVADEASIH 109
Cdd:COG2084    3 KVGFIGLGAMGAPMARNLLKAGHEVTVWNRTPAK--------------------AEALVAAGARVAAS-PAEAAAAADVV 61

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|..
gi 756978273 110 VVIVPTlvDEAgrpdlsVIEAVARD--IAKGLDEGDLVVFESTLPPRSCRDA 159
Cdd:COG2084   62 ITMLPD--DAA------VEEVLLGEdgLLAALRPGAVVVDMSTISPETAREL 105
PRK15461 PRK15461
sulfolactaldehyde 3-reductase;
35-276 1.31e-03

sulfolactaldehyde 3-reductase;


Pssm-ID: 185358 [Multi-domain]  Cd Length: 296  Bit Score: 40.61  E-value: 1.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  35 GLGKMGLPLASVYAETTGNVTGADIDTDVVReinagrnhivgepgldelveELVEDGALVANTePREVADEASIHVVIVP 114
Cdd:PRK15461   8 GLGQMGSPMASNLLKQGHQLQVFDVNPQAVD--------------------ALVDKGATPAAS-PAQAAAGAEFVITMLP 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 115 TlvdeaGRPDLSVIEAvARDIAKGLDEGDLVVFESTLPPRSCrDALLPLLESESglslgeFGLAFCPERTSSGRAlkdIR 194
Cdd:PRK15461  67 N-----GDLVRSVLFG-ENGVCEGLSRDALVIDMSTIHPLQT-DKLIADMQAKG------FSMMDVPVGRTSDNA---IT 130

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273 195 GAYPKVVGGADDESTRAASLIydQISSNEVITVSDTTTAEAVKVFEGvYRDVNI-ALANELATHAGEFEIDVTEAIDVAN 273
Cdd:PRK15461 131 GTLLLLAGGTAEQVERATPIL--MAMGNELINAGGPGMGIRVKLINN-YMSIALnALSAEAAVLCEALGLSFDVALKVMS 207


                 ...
gi 756978273 274 TQP 276
Cdd:PRK15461 208 GTA 210
YqeC COG1023
6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];
31-146 3.55e-03

6-phosphogluconate dehydrogenase (decarboxylating) [Carbohydrate transport and metabolism];


Pssm-ID: 440646 [Multi-domain]  Cd Length: 300  Bit Score: 39.30  E-value: 3.55e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAgrNHIVGEPGLDELVEELvedgalvanTEPREVAdeasihv 110
Cdd:COG1023    3 IGMIGLGKMGGNMARRLLRHGHEVVGYDRNPEAVAALAA--EGATGADSLEELVAKL---------PAPRVVW------- 64

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 756978273 111 VIVPtlvdeAGRPDLSVIEavarDIAKGLDEGDLVV 146
Cdd:COG1023   65 LMVP-----AGEITDQVIE----ELAPLLEPGDIVI 91
PRK09599 PRK09599
NADP-dependent phosphogluconate dehydrogenase;
31-146 7.94e-03

NADP-dependent phosphogluconate dehydrogenase;


Pssm-ID: 236582 [Multi-domain]  Cd Length: 301  Bit Score: 38.19  E-value: 7.94e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  31 VGVYGLGKMGLPLASVYAETTGNVTGADIDTDVVREINAGRnhIVGEPGLDELVEELvedgalvanTEPREVAdeasihv 110
Cdd:PRK09599   3 LGMIGLGRMGGNMARRLLRGGHEVVGYDRNPEAVEALAEEG--ATGADSLEELVAKL---------PAPRVVW------- 64

                         90       100       110
                 ....*....|....*....|....*....|....*.
gi 756978273 111 VIVPtlvdeAGRPdlsvIEAVARDIAKGLDEGDLVV 146
Cdd:PRK09599  65 LMVP-----AGEI----TDATIDELAPLLSPGDIVI 91
PLN02353 PLN02353
probable UDP-glucose 6-dehydrogenase
 77-212 9.52e-03

probable UDP-glucose 6-dehydrogenase


Pssm-ID: 177986 [Multi-domain]  Cd Length: 473  Bit Score: 38.12  E-value: 9.52e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756978273  77 EPGLDELVEELVEDGALVANTEPREVAdEASIHVVIVPTLVDE----AGR-PDLSVIEAVARDIAKGLDEGDLVVFESTL 151
Cdd:PLN02353  51 EPGLDEVVKQCRGKNLFFSTDVEKHVA-EADIVFVSVNTPTKTrglgAGKaADLTYWESAARMIADVSKSDKIVVEKSTV 129

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 756978273 152 PPRSCRDALLPLLESESGLslgEFGLAFCPERTSSGRALKDIRGAYPKVVGGADDESTRAA 212
Cdd:PLN02353 130 PVKTAEAIEKILTHNSKGI---NFQILSNPEFLAEGTAIEDLFKPDRVLIGGRETPEGQKA 187
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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