|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-719 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 534.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 1 MS-SRQGDSRLYSFVILAVLSVTCGVFIAGMGIpfaalasdaagsASSSLNNV--TTQLTIPHQAENSQILLANGDVLAS 77
Cdd:COG0744 1 MAkPRRGKRLLRRLLGLLLLLLAVLVLAALAGL------------VALYVADLpdPEELEDLALPQTSTIYDRDGTLIAT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 78 FFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVV--GNSGGGSTLTQQYVKQVRIQiaqdngdt 155
Cdd:COG0744 69 LGDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTagGVVQGGSTITQQLVKNLFLS-------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 156 kaeqeaQAPTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKDLDLEQSA 235
Cdd:COG0744 141 ------NERTLSRKLKEALLALKLERKYSK---------DEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAA 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 236 MLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGTwftgspqLTSDQVQQAKDIGFdqsKVTENYSGCASSKYPF 315
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMV---EQGY-------ITQAEADAAKAEPL---TLVPPPNGAAAGKYPY 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 316 ICQYTENVLLSDqmssLGADrdarkrALYRGGLKIQTVVEPDAQDAAQSAITALVKPTDP--VVSVAVMTDPKTGLIKAM 393
Cdd:COG0744 273 FVDYVRRELEEL----LGED------DLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKPggLQAALVVVDPKTGEVLAM 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 394 AQskpvmgtNTDAGETYYNYAVGQdmggaeGYQAGSTFKAFVAAAAISEGFIPSQTYYNAPATKNWEGTTFKNCDGNFvf 473
Cdd:COG0744 343 VG-------GRDYGKSQFNRATQA------KRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFPGGGWSPKNYDGRY-- 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 474 ksgdgqgwtvsnswkTGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGMQladsntpmENYQNVPSFTLGALNVT 553
Cdd:COG0744 408 ---------------RGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT--------SPLDPNPSLALGTSEVS 464
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 554 PISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLkTGGTGVASKVPGnYDQAG 633
Cdd:COG0744 465 PLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVV-TSGTGRAARLPG-RPVAG 542
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 634 KTGTagsTETESAVWFNAYTPELEGVAmisvdpgntyWTGRQQTlTGLRTGSGAVLSGNsttesggIWKAMMSAQLPKTP 713
Cdd:COG0744 543 KTGT---TNDNRDAWFVGYTPQLVTAV----------WVGNDDN-SPMGYVTGGSLPAP-------IWRDFMEAALEGLP 601
|
....*.
gi 756352522 714 ATQFAP 719
Cdd:COG0744 602 VEDFPK 607
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
82-711 |
2.01e-111 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 347.71 E-value: 2.01e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 82 NREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVVGNS--GGGSTLTQQYVKqvriqiaqdNGDTKAEQ 159
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRvlEGGSTITQQLAK---------NLYLTNER 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 160 eaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKDLDLEQSAMLAG 239
Cdd:TIGR02074 72 -----TITRKIQEALLALKLEQKLSK---------DEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 240 LVQSPSDTDPVNHPDAAIARRNVVLEQMLKwdqEGTwftgspqLTSDQVQQAKDI---GFDQSKVTENYsgcassKYPFi 316
Cdd:TIGR02074 138 LPKAPSAYNPFKNPERAKDRRNLVLSNMVE---NGY-------ITAEEAEEAINEpiqLYLQTKKSEQY------KAPY- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 317 cqYTENVllsdqmsslgaDRDARKRA---LYRGGLKIQTVVEPDAQDAAQSAI-TALVKPT----DPVVSVAVMTDPKTG 388
Cdd:TIGR02074 201 --FVDYV-----------IQELEEEYgeeLYTGGLKIYTTLDLDAQKAAEKVLnTGLRVAGrrdgDDLQAALVAIDPDTG 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 389 LIKAMaqskpVMGTNTdaGETYYNYAVgQDMggaegYQAGSTFKAFVAAAAISEGFIPSQTYYNAPATknWEGTTF---K 465
Cdd:TIGR02074 268 AVRAL-----VGGRDY--GKSQFNRAT-QAK-----RQPGSTFKPFVYAAALEKGLTPATIVNDEPIT--YNGNGPwspK 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 466 NCDGNFvfksgdgqgwtvsnswkTGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGMQLADsntpmenyQNVPSF 545
Cdd:TIGR02074 333 NYGGGY-----------------RGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL--------DPVLSL 387
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 546 TLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLkTGGTGVASKV 625
Cdd:TIGR02074 388 ALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVV-ESGTGRSARL 466
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 626 PGnYDQAGKTGTagsTETESAVWFNAYTPELEGVAmisvdpgntyWTGRQQTLTGLRTGSGAVLSGNsttesggIWKAMM 705
Cdd:TIGR02074 467 PG-RPVAGKTGT---TQNWRDAWFVGYTPYYVTAV----------WVGYDDKKTLGKSGTGGGLAAP-------IWRDFM 525
|
....*.
gi 756352522 706 SAQLPK 711
Cdd:TIGR02074 526 AEALKN 531
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
71-268 |
5.74e-74 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 237.03 E-value: 5.74e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 71 NGDVLASFFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVVGN--SGGGSTLTQQYVKqvriqi 148
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGriVQGGSTITQQLAK------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 149 aqdNGDTKAEQeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKD 228
Cdd:pfam00912 75 ---NLFLTPER-----TLTRKLKEAVLALKLERRYSK---------DEILEAYLNTVYFGRGAYGIEAAARAYFGKDASD 137
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 756352522 229 LDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQML 268
Cdd:pfam00912 138 LTLAEAALLAGLPQAPSRYNPLRNPERAKRRRNLVLDRMV 177
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
66-719 |
3.24e-42 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 164.92 E-value: 3.24e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 66 QILLANGDVLASFFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAA-LGQVVGN-SGGGSTLTQQYVKq 143
Cdd:PRK11636 49 QVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAAsVALFSGHaSQGASTITQQLAR- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 144 vriqiaqdNGDTKAEQeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFG 223
Cdd:PRK11636 128 --------NFFLSPER-----TLMRKIKEAFLAIRIEQLLTK---------DEILELYLNKIYLGYRAYGVGAAAQVYFG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 224 VNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGtwftgspQLTSDQVQQAKDigfdqSKVTE 303
Cdd:PRK11636 186 KTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRML---DEG-------YITQAQYDQARS-----EPIVA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 304 NYSGcasSKYPFICQYTENVLLSDQMSSLGADRdarkralYRGGLKIQTVVEPDAQDAAQSAITA--------------- 368
Cdd:PRK11636 251 NYHA---PEIAFSAPYLSEMVRQEMYNRYGENA-------YEDGYRVYTTITRKVQQAAQQAVRNnvldydmrhgyrgpa 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 369 --LVKPTDPVVSVAVMTD-----PKTG------LIKAMAQSKPVM---GTN---------------------------TD 405
Cdd:PRK11636 321 nvLWKVGESAWDNKKITDtlkalPTYGpllpavVTSANPQEATAMladGSSvalpmegvrwarpyrsdtqqgptprkvTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 406 ---AGETYYNYAVGQD------------------MGGA-----EGY---------------QAGSTFKAFVAAAAISEGF 444
Cdd:PRK11636 401 vvqTGQQIWVRQVDDAwwlaqvpdvnsalvsinpQNGAvmalvGGFdfnqskfnratqalrQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 445 IPSQTYYNAPATKnWEgttfkncdgnfvfkSGDGQGWTVSNSWKT--GNMNMLTGMGASVNNYFVALERDAGICSSIKMA 522
Cdd:PRK11636 481 TLASMLNDVPISR-WD--------------AGAGSDWRPKNSPPQyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYL 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 523 ETVGMqladsntPMENYQNVPSFTLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGNSL--------------- 587
Cdd:PRK11636 546 QRFGF-------PAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIfeakpkvacpecdip 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 588 -------------------------------------PVPPGNCKQVIDPTVADGV-----NLVMQQVLKTG-------- 617
Cdd:PRK11636 619 viygdtqksnvlenddvenvatsqeqqnssvpmpqleQANQALVAQNGAQEYAPHVintplAFLIKSALNTNifgepgwm 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 618 GTG-VASKVPGNYDQAGKTGTAGSTETesaVWFNAYTPELEGVAMISVDpgntywtGRQQTLtGLRTGSGAVLSGNSTTE 696
Cdd:PRK11636 699 GTGwRAGRDLKRRDIGGKTGTTNSSKD---AWFSGYGPGVVTSVWIGFD-------DHRRDL-GRTTASGAIKDQISGYE 767
|
810 820
....*....|....*....|....*...
gi 756352522 697 SGG-----IWKAMMSAQLPKTPATQFAP 719
Cdd:PRK11636 768 GGAksaqpAWDDYMKAALEGVPEQPLTP 795
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| MrcB |
COG0744 |
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall ... |
1-719 |
0e+00 |
|
Penicillin-binding protein 1B/1F, peptidoglycan transglycosylase/transpeptidase [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440507 [Multi-domain] Cd Length: 630 Bit Score: 534.50 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 1 MS-SRQGDSRLYSFVILAVLSVTCGVFIAGMGIpfaalasdaagsASSSLNNV--TTQLTIPHQAENSQILLANGDVLAS 77
Cdd:COG0744 1 MAkPRRGKRLLRRLLGLLLLLLAVLVLAALAGL------------VALYVADLpdPEELEDLALPQTSTIYDRDGTLIAT 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 78 FFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVV--GNSGGGSTLTQQYVKQVRIQiaqdngdt 155
Cdd:COG0744 69 LGDENREWVPLDQIPPHLKDAVVAIEDRRFYEHGGVDPKGIARALVANLTagGVVQGGSTITQQLVKNLFLS-------- 140
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 156 kaeqeaQAPTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKDLDLEQSA 235
Cdd:COG0744 141 ------NERTLSRKLKEALLALKLERKYSK---------DEILELYLNTVYFGRGAYGIEAAAQYYFGKSASDLTLAEAA 205
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 236 MLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGTwftgspqLTSDQVQQAKDIGFdqsKVTENYSGCASSKYPF 315
Cdd:COG0744 206 LLAGLVKAPSYYDPYRNPEAAKERRNLVLDRMV---EQGY-------ITQAEADAAKAEPL---TLVPPPNGAAAGKYPY 272
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 316 ICQYTENVLLSDqmssLGADrdarkrALYRGGLKIQTVVEPDAQDAAQSAITALVKPTDP--VVSVAVMTDPKTGLIKAM 393
Cdd:COG0744 273 FVDYVRRELEEL----LGED------DLYRGGLKIYTTLDPKLQKAAEKAVKNVLPEGKPggLQAALVVVDPKTGEVLAM 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 394 AQskpvmgtNTDAGETYYNYAVGQdmggaeGYQAGSTFKAFVAAAAISEGFIPSQTYYNAPATKNWEGTTFKNCDGNFvf 473
Cdd:COG0744 343 VG-------GRDYGKSQFNRATQA------KRQPGSTFKPFVYAAALEQGYTPATTVDDEPVTFPGGGWSPKNYDGRY-- 407
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 474 ksgdgqgwtvsnswkTGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGMQladsntpmENYQNVPSFTLGALNVT 553
Cdd:COG0744 408 ---------------RGPVTLREALANSLNTPAVRLAQEVGLDKVVDTARRLGIT--------SPLDPNPSLALGTSEVS 464
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 554 PISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLkTGGTGVASKVPGnYDQAG 633
Cdd:COG0744 465 PLEMASAYATFANGGVYVEPHAITKVTDADGKVLYEAKPKCEQVISPEVAYLMTDMLQDVV-TSGTGRAARLPG-RPVAG 542
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 634 KTGTagsTETESAVWFNAYTPELEGVAmisvdpgntyWTGRQQTlTGLRTGSGAVLSGNsttesggIWKAMMSAQLPKTP 713
Cdd:COG0744 543 KTGT---TNDNRDAWFVGYTPQLVTAV----------WVGNDDN-SPMGYVTGGSLPAP-------IWRDFMEAALEGLP 601
|
....*.
gi 756352522 714 ATQFAP 719
Cdd:COG0744 602 VEDFPK 607
|
|
| PBP_1a_fam |
TIGR02074 |
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan ... |
82-711 |
2.01e-111 |
|
penicillin-binding protein, 1A family; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of bifunctional transglycosylase/transpeptidase penicillin-binding proteins (PBP). In the Proteobacteria, this family includes PBP 1A but not the paralogous PBP 1B (TIGR02071). This family also includes related proteins, often designated PBP 1A, from other bacterial lineages. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273955 [Multi-domain] Cd Length: 531 Bit Score: 347.71 E-value: 2.01e-111
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 82 NREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVVGNS--GGGSTLTQQYVKqvriqiaqdNGDTKAEQ 159
Cdd:TIGR02074 1 RREYVPIDDIPENLINAFLAIEDRRFYDHFGIDLKGIGRAAVANITSGRvlEGGSTITQQLAK---------NLYLTNER 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 160 eaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKDLDLEQSAMLAG 239
Cdd:TIGR02074 72 -----TITRKIQEALLALKLEQKLSK---------DEILELYLNRIYFGNGAYGIEAAAQFYFGKSVNDLTLAEAAMLAG 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 240 LVQSPSDTDPVNHPDAAIARRNVVLEQMLKwdqEGTwftgspqLTSDQVQQAKDI---GFDQSKVTENYsgcassKYPFi 316
Cdd:TIGR02074 138 LPKAPSAYNPFKNPERAKDRRNLVLSNMVE---NGY-------ITAEEAEEAINEpiqLYLQTKKSEQY------KAPY- 200
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 317 cqYTENVllsdqmsslgaDRDARKRA---LYRGGLKIQTVVEPDAQDAAQSAI-TALVKPT----DPVVSVAVMTDPKTG 388
Cdd:TIGR02074 201 --FVDYV-----------IQELEEEYgeeLYTGGLKIYTTLDLDAQKAAEKVLnTGLRVAGrrdgDDLQAALVAIDPDTG 267
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 389 LIKAMaqskpVMGTNTdaGETYYNYAVgQDMggaegYQAGSTFKAFVAAAAISEGFIPSQTYYNAPATknWEGTTF---K 465
Cdd:TIGR02074 268 AVRAL-----VGGRDY--GKSQFNRAT-QAK-----RQPGSTFKPFVYAAALEKGLTPATIVNDEPIT--YNGNGPwspK 332
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 466 NCDGNFvfksgdgqgwtvsnswkTGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGMQLADsntpmenyQNVPSF 545
Cdd:TIGR02074 333 NYGGGY-----------------RGNVTLRQALAQSRNIPAVRLLQEVGLDKVVALAKRFGITSPL--------DPVLSL 387
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 546 TLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLkTGGTGVASKV 625
Cdd:TIGR02074 388 ALGTVEVSPLEMASAYAVFANGGKYVEPHGIRKIVDRDGKVIYENKPKTTQVISPATAYIMTDMLKGVV-ESGTGRSARL 466
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 626 PGnYDQAGKTGTagsTETESAVWFNAYTPELEGVAmisvdpgntyWTGRQQTLTGLRTGSGAVLSGNsttesggIWKAMM 705
Cdd:TIGR02074 467 PG-RPVAGKTGT---TQNWRDAWFVGYTPYYVTAV----------WVGYDDKKTLGKSGTGGGLAAP-------IWRDFM 525
|
....*.
gi 756352522 706 SAQLPK 711
Cdd:TIGR02074 526 AEALKN 531
|
|
| MrcA |
COG5009 |
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis]; |
65-719 |
1.94e-95 |
|
Membrane carboxypeptidase/penicillin-binding protein [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 444033 [Multi-domain] Cd Length: 785 Bit Score: 313.25 E-value: 1.94e-95
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 65 SQILLANGDVLASFFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVV--GNSGGGSTLTQQYVK 142
Cdd:COG5009 48 SRVYSADGKLIAEFGEERRIPVPIEEIPPLLINAFLAAEDKRFYEHPGVDPIGIARAAVVNLRtgRRVQGGSTITQQVAK 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 143 QVRIQiaqdngdtkAEQeaqapTMSRKILEMRYAVALEQELTKQKgslkaakdaILENYLNIAYYGDGAYGVQAAAKHYF 222
Cdd:COG5009 128 NFLLS---------PER-----TLTRKIKEAILALRIEQELSKDE---------ILELYLNKIYLGHRAYGVAAAAQTYF 184
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 223 GVNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLKwdqEGtwFtgspqLTSDQVQQAKdigfdQSKVT 302
Cdd:COG5009 185 GKSLDELTLAEAAMLAGLPKAPSRYNPIRNPERALERRNYVLGRMLE---LG--Y-----ITQAEYEAAK-----AEPLT 249
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 303 ENYSGcasSKYPFICQY-TENV--LLSDQmssLGADrdarkrALYRGGLKIQTVVEPDAQDAAQSA-------------- 365
Cdd:COG5009 250 ARYHG---ASAEVDAPYfAEMVrrELVER---YGED------ALYTGGLKVYTTLDPRLQEAAEKAlrdgllaydrrhgy 317
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 366 ---------------------------ITALV------------------------------------------------ 370
Cdd:COG5009 318 rgpeahldlaeedwdealaevpdvgdlRPAVVlevddksarvglrdgetgtlpleglkwarpyindnrrgpapksasdvl 397
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 371 KPTD-----------------PVVSVAVMT-DPKTGLIKAM------AQSKpvmgtntdagetyYNYAVgqdmggaegyQ 426
Cdd:COG5009 398 KPGDvirvrpvadggwrlrqiPEVQGALVAlDPHTGAVLALvggfdfEQSK-------------FNRAT----------Q 454
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 427 A----GSTFKAFVAAAAISEGFIPSQTYYNAPatknwegttfkncdgnFVFKSGDGQG-WTVSNSWKT--GNMNMLTGMG 499
Cdd:COG5009 455 AkrqpGSSFKPFVYAAALDNGYTPATIINDAP----------------IVFDDGGGGGvWRPKNYSGKfyGPTTLREALE 518
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 500 ASVNNYFVALERDAGICSSIKMAETVGMQladsntpmENYQNVPSFTLGALNVTPISMAEAYATFANRGIHCDPVILASA 579
Cdd:COG5009 519 KSRNLVTVRLLQDVGIDYVIDYAERFGIY--------SKLPPNLSLALGSGEVTPLEMARAYAVFANGGYRVEPYLIDRI 590
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 580 KTADGN---------------------SLPVPPGNCKQVIDPTVADGVNLVMQQVLKtGGTGVASKVPGnYDQAGKTGTa 638
Cdd:COG5009 591 EDRNGKviyradparacedcdaaewdgAEPRLPDPAEQVIDPRTAYQMTSMLRGVVQ-RGTGRRARALG-RDIAGKTGT- 667
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 639 gsTETESAVWFNAYTPELegVAmisvdpgnTYWTG--RQQTLTGLRTGSGAVLsgnsttesgGIWKAMMSAQLPKTPATQ 716
Cdd:COG5009 668 --TNDSKDAWFVGFTPDL--VA--------GVWVGfdDPRSLGRGETGGRAAL---------PIWIDFMKAALKDKPEKP 726
|
...
gi 756352522 717 FAP 719
Cdd:COG5009 727 FPV 729
|
|
| Transgly |
pfam00912 |
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of ... |
71-268 |
5.74e-74 |
|
Transglycosylase; The penicillin-binding proteins are bifunctional proteins consisting of transglycosylase and transpeptidase in the N- and C-terminus respectively. The transglycosylase domain catalyzes the polymerization of murein glycan chains.
Pssm-ID: 459993 [Multi-domain] Cd Length: 177 Bit Score: 237.03 E-value: 5.74e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 71 NGDVLASFFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVVGN--SGGGSTLTQQYVKqvriqi 148
Cdd:pfam00912 1 DGTLLAELGEENREYVPLDDIPPALKNAVLAIEDRRFYEHGGVDPKGIARALLSNLRSGriVQGGSTITQQLAK------ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 149 aqdNGDTKAEQeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGVNAKD 228
Cdd:pfam00912 75 ---NLFLTPER-----TLTRKLKEAVLALKLERRYSK---------DEILEAYLNTVYFGRGAYGIEAAARAYFGKDASD 137
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 756352522 229 LDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQML 268
Cdd:pfam00912 138 LTLAEAALLAGLPQAPSRYNPLRNPERAKRRRNLVLDRMV 177
|
|
| PBP_1b |
TIGR02071 |
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) ... |
81-712 |
7.75e-53 |
|
penicillin-binding protein 1B; Bacterial that synthesize a cell wall of peptidoglycan (murein) generally have several transglycosylases and transpeptidases for the task. This family consists of a particular bifunctional transglycosylase/transpeptidase in E. coli and other Proteobacteria, designated penicillin-binding protein 1B. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273952 [Multi-domain] Cd Length: 730 Bit Score: 195.32 E-value: 7.75e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 81 QNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAAL-----GQVVGnsgGGSTLTQQYVKQVRIQIAQdngdt 155
Cdd:TIGR02071 145 EQRLFVPRDQFPELLVDTLLATEDRDFYEHDGISLYSIGRAVWvnltaGRTVQ---GGSTLTQQLVKNLFLSNER----- 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 156 kaeqeaqapTMSRKILEMRYAVALEqeltkqkgsLKAAKDAILENYLNIAYYG-DGA---YGVQAAAKHYFGVNAKDLDL 231
Cdd:TIGR02071 217 ---------SLWRKANEAYMALILD---------ARYSKDRILELYLNEVYLGqSGDdaiHGFPLASQYYFGRPLGELSL 278
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 232 EQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLKWDqegtwftgspQLTSDQVQQAKDIGFDQSKvtenySGCASS 311
Cdd:TIGR02071 279 DQVALLVGMVKGPSYYNPWRNPDRALERRNLVLRLLQEQK----------IIDDEEYDMLSARPLGVQK-----KGGIIS 343
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 312 KYPFICQytenvLLSDQMSslgadRDARKRALYRGGLKIQTVVEPDAQDAAQSAIT------ALVKPTDPVVSVAVMTDP 385
Cdd:TIGR02071 344 RQPAFLQ-----LVRRELR-----QKLGDKVKDLSGLRIFTTLDPVSQSAAEQAVQetipalKKKKKLPDLEAAMVVTDR 413
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 386 KTGLIKAMAQSKpvmgtntDAGETYYNYAVGQDMggaegyQAGSTFKAFVAAAAISEgfiPSQTYYNAPATknwegttfk 465
Cdd:TIGR02071 414 FTGEVRAMVGGS-------DPQFAGFNRALQARR------QIGSLVKPAVYLTALSQ---PDKYRLNTWIE--------- 468
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 466 ncDGNFVFKSGDGQGWTVSNSWK--TGNMNMLTGMGASVNNYFVALERDAGICssiKMAETVGmQLADSNTPMEnyqNVP 543
Cdd:TIGR02071 469 --DQPLSIKLSNGQVWSPQNYDRrySGTVMLYDALAHSLNIPTVNLGMKVGLP---KVSQTWN-KLGINKDEIP---PVP 539
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 544 SFTLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLKTGGTGVAS 623
Cdd:TIGR02071 540 SMLLGAINLTPYEVAQLYQTIASGGNRAPLSAVRSVLDEDGKVLYQSDPQAEQAVPSQAAYLTLYAMQQVVQRGTARSLG 619
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 624 KVPGNYDQAGKTGTagsTETESAVWFNAYTPELEGVAmisvdpgntyWTGRQQT-LTGLRTGSGAVlsgnsttesgGIWK 702
Cdd:TIGR02071 620 ADFPSLSLAGKTGT---TNDNRDSWFAGIDGKEVTII----------WLGRDDNgPTKLTGASGAL----------QVYA 676
|
650
....*....|
gi 756352522 703 AMMSAQLPKT 712
Cdd:TIGR02071 677 RYLSYQTPEP 686
|
|
| PbpC |
COG4953 |
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope ... |
61-637 |
7.08e-47 |
|
Membrane carboxypeptidase/penicillin-binding protein PbpC [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 443980 [Multi-domain] Cd Length: 773 Bit Score: 178.49 E-value: 7.08e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 61 QAENSQILLA-NGDVLASFFDQN---REPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAAL-----GQVVgnSG 131
Cdd:COG4953 39 AVPYSTVVLDrDGTLLRAFLAADgqwRLPVPLDEVSPRYLQALLAYEDRRFYYHPGVNPLALLRAAWqnlrsGRIV--SG 116
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 132 GgSTLTQQyVkqVRIQiaqdngdtkaeqEAQAPTMSRKILEMRYAVALEQELTKQKgslkaakdaILENYLNIAYYGDGA 211
Cdd:COG4953 117 G-STLTMQ-V--ARLL------------EPRPRTLSGKLRQILRALQLERRYSKDE---------ILELYLNLAPYGGNI 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 212 YGVQAAAKHYFGVNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGTWftgspqlTSDQVQQA 291
Cdd:COG4953 172 EGVEAASLAYFGKPPSRLSLAEAALLAVLPQAPSRRRPDRNPERARAARDRVLARLA---EAGVI-------DAEEAALA 241
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 292 KdigfdQSKVTEnysgcASSKYPFICQytenvLLSDQMsslgadrdarkRALYRGGLKIQTVVEPDAQ----DAAQSAIT 367
Cdd:COG4953 242 L-----LEPVPA-----RRRPLPQLAP-----HLARRL-----------LRQLPGGTRIRTTLDAGLQrrleRLVRRYVR 295
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 368 ALVKPtdPVVSVAVM-TDPKTGLIKAMaqskpvMGtNTDagetYYNyavgQDMGGA-EGYQA----GSTFKAFVAAAAIS 441
Cdd:COG4953 296 RLKQN--GIHNAAVLvVDNRTGEVLAY------VG-SAD----FFD----ASRQGQvDMVRAlrspGSTLKPFLYGLALD 358
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 442 EGFIPSQTY-YNAPAtkNWEGTTFKNCDGNFvfksgdgQGwTVS------NSwktgnMN-----MLTGMGASVnnyFVAL 509
Cdd:COG4953 359 QGLIHPETLlADVPT--SFGGYRPENFDGTF-------QG-PVSarealaRS-----LNipavrLLEALGPAR---FYAR 420
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 510 ERDAGICSSIKMAETVGMQLAdsntpmenyqnvpsftLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGnslpv 589
Cdd:COG4953 421 LRRAGLRLLLPPAEHYGLSLI----------------LGGAEVTLEELVGLYAALARGGEARPLRLLAGEPASPG----- 479
|
570 580 590 600
....*....|....*....|....*....|....*....|....*...
gi 756352522 590 ppgncKQVIDPTVADGVNLVMQQVLKTGGTGVASKVPGNYDQAGKTGT 637
Cdd:COG4953 480 -----RRLLSPGAAWLVRDILSDVPRPDGAFGWRALDSPPPIAWKTGT 522
|
|
| mrcA |
PRK11636 |
penicillin-binding protein 1a; Provisional |
66-719 |
3.24e-42 |
|
penicillin-binding protein 1a; Provisional
Pssm-ID: 183248 [Multi-domain] Cd Length: 850 Bit Score: 164.92 E-value: 3.24e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 66 QILLANGDVLASFFDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAA-LGQVVGN-SGGGSTLTQQYVKq 143
Cdd:PRK11636 49 QVYSADGELIAQYGEKRRIPLTLDQIPPEMVKAFIATEDSRFYEHHGVDPVGIFRAAsVALFSGHaSQGASTITQQLAR- 127
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 144 vriqiaqdNGDTKAEQeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFG 223
Cdd:PRK11636 128 --------NFFLSPER-----TLMRKIKEAFLAIRIEQLLTK---------DEILELYLNKIYLGYRAYGVGAAAQVYFG 185
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 224 VNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGtwftgspQLTSDQVQQAKDigfdqSKVTE 303
Cdd:PRK11636 186 KTVDQLTLSEMAVIAGLPKAPSTFNPLYSMDRAVARRNVVLSRML---DEG-------YITQAQYDQARS-----EPIVA 250
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 304 NYSGcasSKYPFICQYTENVLLSDQMSSLGADRdarkralYRGGLKIQTVVEPDAQDAAQSAITA--------------- 368
Cdd:PRK11636 251 NYHA---PEIAFSAPYLSEMVRQEMYNRYGENA-------YEDGYRVYTTITRKVQQAAQQAVRNnvldydmrhgyrgpa 320
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 369 --LVKPTDPVVSVAVMTD-----PKTG------LIKAMAQSKPVM---GTN---------------------------TD 405
Cdd:PRK11636 321 nvLWKVGESAWDNKKITDtlkalPTYGpllpavVTSANPQEATAMladGSSvalpmegvrwarpyrsdtqqgptprkvTD 400
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 406 ---AGETYYNYAVGQD------------------MGGA-----EGY---------------QAGSTFKAFVAAAAISEGF 444
Cdd:PRK11636 401 vvqTGQQIWVRQVDDAwwlaqvpdvnsalvsinpQNGAvmalvGGFdfnqskfnratqalrQVGSNIKPFLYTAAMDKGL 480
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 445 IPSQTYYNAPATKnWEgttfkncdgnfvfkSGDGQGWTVSNSWKT--GNMNMLTGMGASVNNYFVALERDAGICSSIKMA 522
Cdd:PRK11636 481 TLASMLNDVPISR-WD--------------AGAGSDWRPKNSPPQyaGPIRLRQGLGQSKNVVMVRAMRAMGVDYAAEYL 545
|
570 580 590 600 610 620 630 640
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 523 ETVGMqladsntPMENYQNVPSFTLGALNVTPISMAEAYATFANRGIHCDPVILASAKTADGNSL--------------- 587
Cdd:PRK11636 546 QRFGF-------PAQNIVHTESLALGSASFTPMQVARGYAVMANGGFLVDPYFISKIENDQGGVIfeakpkvacpecdip 618
|
650 660 670 680 690 700 710 720
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 588 -------------------------------------PVPPGNCKQVIDPTVADGV-----NLVMQQVLKTG-------- 617
Cdd:PRK11636 619 viygdtqksnvlenddvenvatsqeqqnssvpmpqleQANQALVAQNGAQEYAPHVintplAFLIKSALNTNifgepgwm 698
|
730 740 750 760 770 780 790 800
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 618 GTG-VASKVPGNYDQAGKTGTAGSTETesaVWFNAYTPELEGVAMISVDpgntywtGRQQTLtGLRTGSGAVLSGNSTTE 696
Cdd:PRK11636 699 GTGwRAGRDLKRRDIGGKTGTTNSSKD---AWFSGYGPGVVTSVWIGFD-------DHRRDL-GRTTASGAIKDQISGYE 767
|
810 820
....*....|....*....|....*...
gi 756352522 697 SGG-----IWKAMMSAQLPKTPATQFAP 719
Cdd:PRK11636 768 GGAksaqpAWDDYMKAALEGVPEQPLTP 795
|
|
| PBP_1c |
TIGR02073 |
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the ... |
67-637 |
2.53e-38 |
|
penicillin-binding protein 1C; This subfamily of the penicillin binding proteins includes the member from E. coli designated penicillin-binding protein 1C. Members have both transglycosylase and transpeptidase domains and are involved in forming cross-links in the late stages of peptidoglycan biosynthesis. All members of this subfamily are presumed to have the same basic function. [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273954 [Multi-domain] Cd Length: 727 Bit Score: 152.19 E-value: 2.53e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 67 ILLANGDVLASFF---DQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVVGNS--GGGSTLTQQYV 141
Cdd:TIGR02073 14 VLDRHGTLLRALLandGQWRLPVPLEDISPKFLQALLLYEDKRFYWHPGVNPLALLRAAWQNLTNGRrvSGGSTLTMQLA 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 142 KQVriqiaqDNGDTKaeqeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHY 221
Cdd:TIGR02073 94 RLL------DPELSR--------TLTGKLRQMWRAIQLEARYSK---------REILEAYLNLAPYGGNLEGLRAASLIY 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 222 FGVNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLkwdQEGTWftgspqltsDQVQQAKDIgfdqskv 301
Cdd:TIGR02073 151 FGKEPSSLSLAEAALLAALPQAPSARRLDRLPKAAKAARDRLLDRMV---EQGPD---------DSEQVALAA------- 211
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 302 tENYSGCASSKYPFICQYtenvlLSDQMsslgadRDARKRALYrgglKIQTVVEPDAQ----DAAQSAITALvkPTDPVV 377
Cdd:TIGR02073 212 -LEPLPALPEPLPQLAPH-----FALKL------LRARPEIAS----VIVSTLDADLQrrleELARRYLSAL--RPRGIS 273
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 378 SVAVMT-DPKTGLIKAMAQSkpvmgtntdaGETYYNYAVGQ-DMGGAEgYQAGSTFKAFVAAAAISEGFIPSQTYY-NAP 454
Cdd:TIGR02073 274 NLAILVvDNRSGAVLAYVGS----------ADFFDDSNSGQvDGVRAP-RSPGSTLKPFLYALALDDGLLHPDSLLkDVP 342
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 455 AtkNWEGTTFKNCDGNFvfksgdgqgwtvsnswkTGNMNMLTGMGASVNnyfvalerdagiCSSIKMAETVG-------M 527
Cdd:TIGR02073 343 L--RFGDYAPENFDKTF-----------------HGPVPAREALARSLN------------IPAVRLLERVGpprfadfL 391
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 528 QLADSNTPMENyQNVP--SFTLGALNVTPISMAEAYATFANRGIhcdpvilASAKTADGNSLPVPPGncKQVIDPTVADG 605
Cdd:TIGR02073 392 RQAGLNLLKPK-SDYYglSLALGGAEITLQDLANLYAMLANQGL-------SGPLRFLQTDAKRPER--ERLLSPGAAWI 461
|
570 580 590
....*....|....*....|....*....|..
gi 756352522 606 VNLVMQQVLKTGGTGVASKVPGNYDQAGKTGT 637
Cdd:TIGR02073 462 VLDILKDRPRPDDTLPLSALPTRLPLAWKTGT 493
|
|
| FtsI |
COG0768 |
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell ... |
357-654 |
3.76e-31 |
|
Cell division protein FtsI, peptidoglycan transpeptidase (Penicillin-binding protein 2) [Cell cycle control, cell division, chromosome partitioning, Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440531 [Multi-domain] Cd Length: 568 Bit Score: 128.79 E-value: 3.76e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 357 DAQDAAQSAITALVKPTDPVVSVAVMTDPKTGLIKAMAqSKPVMGTNT---DAGETYYNYAVgQDMggaegYQAGSTFKA 433
Cdd:COG0768 228 DLQKIAEEALKKAVEEYKAKSGAVVVMDPKTGEILAMA-SYPSFDPNLfvgGPDEPLRNRAV-QGT-----YEPGSTFKP 300
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 434 FVAAAAISEGFIPSQTYYNAPATKNWEGTTFKNcdgnfvfksgdgqgwtvSNSWKTGNMNMLTGMGASVNNYFVALERDA 513
Cdd:COG0768 301 FTAAAALEEGVITPDTTFDCPGYYRVGGRTIRD-----------------WDRGGHGTLTLTEALAKSSNVGFYKLALRL 363
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 514 GICSSIKMAETVGM-QLADSNTPMENYQNVPS---------FTLG---ALNVTPISMAEAYATFANRGIHCDPVILASAK 580
Cdd:COG0768 364 GIDKLYDYLKKFGLgQKTGIDLPGEASGLLPSpkrwypgetATMSigqGLSVTPLQLAQAYAAIANGGVLVKPHLVKEIV 443
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 581 TADGNSLPVPPGNCKQVIDPTVADGVNLVMQQV-LKTGGTGVASKVPGnYDQAGKTGTA--------GSTETESAVWFNA 651
Cdd:COG0768 444 DPDGEVVKEEPEVLRRVISPETAETVREGMEGVvNEPGGTARRAAIPG-YRVAGKTGTAqvvdigngGYYKGRHIASFVG 522
|
...
gi 756352522 652 YTP 654
Cdd:COG0768 523 FAP 525
|
|
| mrcB |
PRK09506 |
bifunctional glycosyl transferase/transpeptidase; Reviewed |
100-637 |
3.43e-28 |
|
bifunctional glycosyl transferase/transpeptidase; Reviewed
Pssm-ID: 236544 [Multi-domain] Cd Length: 830 Bit Score: 121.42 E-value: 3.43e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 100 MAIEDHRFYDHGAVDAQGILRAALGQVVGNSG--GGSTLTQQYVKQVRIqiaqdngdtkaeqeAQAPTMSRKILEMRYAV 177
Cdd:PRK09506 228 LATEDRHFYEHDGISLYSIGRAVLANLTAGRTvqGGSTLTQQLVKNLFL--------------SNERSLWRKANEAYMAL 293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 178 ALEQeltkqkgslKAAKDAILENYLNIAYYG----DGAYGVQAAAKHYFGVNAKDLDLEQSAMLAGLVQSPSDTDPVNHP 253
Cdd:PRK09506 294 IMDA---------RYSKDRILELYLNEVYLGqsgdDQIRGFPLASLYYFGRPVEELSLDQQALLVGMVKGASLYNPWRNP 364
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 254 DAAIARRNVVLEQMLKwdqegtwftgspQLTSDQ----VQQAKDIGFdQSKvtenysGCASSKYPFICQYTENVL---LS 326
Cdd:PRK09506 365 KLALERRNLVLRLLQQ------------QQIIDQelydMLSARPLGV-QPK------GGVISPQPAFMQMVRQELqakLG 425
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 327 DQMSSLgadrdarkralyrGGLKIQTVVEPDAQDAAQSA----ITALVKP--TDPVVSVAVMTDPKTGLIKAMaqskpVM 400
Cdd:PRK09506 426 DKVKDL-------------SGVKIFTTLDPVSQDAAEKAveegIPALKKQrkLSDLETAMVVVDRFSGEVRAM-----VG 487
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 401 GTNTD-AGetyYNYAVgqdmggaegyQA----GSTFKAFVAAAAISEgfiPSQTYYNAPATknwegttfkncDGNFVFKS 475
Cdd:PRK09506 488 GSEPQfAG---YNRAM----------QArrsiGSLAKPATYLTALSQ---PDKYRLNTWIA-----------DAPISLRQ 540
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 476 GDGQGWTVSNSWK--TGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGMqladsntPMENYQNVPSFTLGALNVT 553
Cdd:PRK09506 541 PNGQVWSPQNDDRrfSGRVMLVDALTRSMNVPTVNLGMALGLPAVTDTWIKLGV-------PKDQLNPVPAMLLGALNLT 613
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 554 PISMAEAYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLKTG-GTGVASKVPgNYDQA 632
Cdd:PRK09506 614 PIEVAQAFQTIASGGNRAPLSALRSVIAEDGKVLYQSFPQAERAVPAQAAYLTLYTMQQVVQRGtGRQLGAKYP-NLHLA 692
|
....*
gi 756352522 633 GKTGT 637
Cdd:PRK09506 693 GKTGT 697
|
|
| mono_pep_trsgly |
TIGR02070 |
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the ... |
86-267 |
1.30e-27 |
|
monofunctional biosynthetic peptidoglycan transglycosylase; This family is one of the transglycosylases involved in the late stages of peptidoglycan biosynthesis. Members tend to be small, about 240 amino acids in length, and consist almost entirely of a domain described by pfam00912 for transglycosylases. Species with this protein will have several other transglycosylases as well. All species with this protein are Proteobacteria that produce murein (peptidoglycan). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 273951 [Multi-domain] Cd Length: 224 Bit Score: 111.40 E-value: 1.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 86 VGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRA-----ALGQVVGnsgGGSTLTQQYVKQVRIQIAQdngdtkaeqe 160
Cdd:TIGR02070 58 RPYDQISPNLKRAVIASEDAKFVEHHGFDWEAIQDAlekneKSGKVVR---GGSTISQQLAKNLFLWSGR---------- 124
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 161 aqapTMSRKILEMRYAVALEQELTKQKgslkaakdaILENYLNIAYYGDGAYGVQAAAKHYFGVNAKDLDLEQSAMLAGL 240
Cdd:TIGR02070 125 ----SYLRKGLEAWATWMLETWWSKQR---------ILEVYLNSVEWGNGVFGAEAAARYYFKRSASNLTRGQAARLAAV 191
|
170 180
....*....|....*....|....*...
gi 756352522 241 VQSPSDTDpVNHPDAAIARR-NVVLEQM 267
Cdd:TIGR02070 192 LPNPKYYD-ENRPGPYVRRKaTWILKQM 218
|
|
| Transpeptidase |
pfam00905 |
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss: ... |
380-654 |
1.76e-25 |
|
Penicillin binding protein transpeptidase domain; The active site serine (residue 337 in Swiss:P14677) is conserved in all members of this family.
Pssm-ID: 425939 [Multi-domain] Cd Length: 296 Bit Score: 107.12 E-value: 1.76e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 380 AVMTDPKTGLIKAMAqSKPVMGTNTDAGeTYYNYAVgqdmggAEGYQAGSTFKAFVAAAAISEGFIPSQTYYNAPATKNW 459
Cdd:pfam00905 3 AVVLDPKTGEVLAMV-GKPSYDPNGFIG-PLRNRAV------TSRYEPGSTFKPFTALAALDNGVLKPDETIFDWPGKQQ 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 460 EGTTFKNcdgnfvfksgdgqgWTVSNswkTGNMNMLTGMGASVNNYFVALERDAGICSSIKMAETVGM-QLADSNTPMEN 538
Cdd:pfam00905 75 GGKSIGD--------------WNQDQ---VGIGTLRQALEYSSNWYMQKLAQKLGADKLRSYLKKFGYgNKTGIGLPGEN 137
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 539 YQNVPSFTLGA--------LNVTPISMAEAYATFANRGIHCDPVILASAKtadgNSLPVPPGNcKQVIDPTVADGVNLVM 610
Cdd:pfam00905 138 AGYLTPYWLEGatasfgigLTITPLQQAQAYAAIANGGKLVPPHLVKSIE----DKVDPKVLN-KLPISKSTAEKVKDML 212
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|..
gi 756352522 611 QQVLKTGGTGVASKVPGnYDQAGKTGTA--------GSTETESAVWFNAYTP 654
Cdd:pfam00905 213 RLVVNDGTGTGTAAVPG-YKVAGKTGTAqvagpkggGYYDGAQIGWFVGYAP 263
|
|
| PRK14850 |
PRK14850 |
penicillin-binding protein 1b; Provisional |
100-689 |
7.16e-25 |
|
penicillin-binding protein 1b; Provisional
Pssm-ID: 237835 [Multi-domain] Cd Length: 764 Bit Score: 110.71 E-value: 7.16e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 100 MAIEDHRFYDHGAVDAQGILRAALGQVV-GNS-GGGSTLTQQYVKQVRIqiaqdngdtkaeqeAQAPTMSRKILEMRYAV 177
Cdd:PRK14850 174 LAIEDKYFYEHDGIHLSSIGRAFLVNLMsGHTiQGGSTLTQQLVKNLFL--------------TNTRSLWRKINEIYMAL 239
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 178 ALEQELTKqkgslkaakDAILENYLNIAYYG----DGAYGVQAAAKHYFGVNAKDLDLEQSAMLAGLVQSPSDTDPVNHP 253
Cdd:PRK14850 240 ILDRFYSK---------DRILELYLNEVYLGqdgnEQIRGFPLASIYYFGRPINELNLDQYALLVGMVKGASLYNPWTNP 310
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 254 DAAIARRNVVLEQMlkwdqegtwftgspqltsdqvqqakdigFDQSKVTENYSGCASSKyPFICQYTENVLLSDQMSSLG 333
Cdd:PRK14850 311 NLTLKRRNLVLFLL----------------------------YKQKVITRKLYKDLCSR-PLNVQSKGNIISSHPAFIQL 361
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 334 ADRDARKRALYR----GGLKIQTVVEPDAQDAAQSAITALV-------KPTDPVVSVaVMTDPKTGLIKAM-AQSKPVMG 401
Cdd:PRK14850 362 VCEEFHKKIHYPfknfSGTKIFTTLDYISQNAAEQAVKIGIpilkrkkRLKDLEVAM-VIIDRFSGEVRALiGSSKPEFN 440
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 402 TntdagetyYNYAVGQDMggaegyQAGSTFKAFVAAAAISEgfiPSQTYYNapatkNWEGTTfkncdgNFVFKSGDGQGW 481
Cdd:PRK14850 441 G--------YNRALKARR------SIGSLSKPITYLTALSQ---PEKYHLN-----TWISDT------PISIKLDNGQYW 492
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 482 TVSNSWK--TGNMNMLTGMGASVNNYFVALERDAGIcssIKMAETVgMQLADSNTPMENYqnvPSFTLGALNVTPISMAE 559
Cdd:PRK14850 493 TPKNNNFsfSGKVMLIDALIHSINIPTVHLSINLGL---KKLVDSW-ILLGISSNYITPL---PSISLGAINLTPMEVAQ 565
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 560 AYATFANRGIHCDPVILASAKTADGNSLPVPPGNCKQVIDPTVADGVNLVMQQVLKTGGTGVASKVPGNYDQAGKTGTag 639
Cdd:PRK14850 566 VFQIIGSGGYKSSLSSIRSIISDDNKVLYQNFPQSKHVESSQASYLTLYAMQQVVKSGTAKSLGTIFKEFSLAGKTGT-- 643
|
570 580 590 600 610
....*....|....*....|....*....|....*....|....*....|
gi 756352522 640 sTETESAVWFNAytpeLEGVAMISVdpgntyWTGRQQTLTGLRTGSGAVL 689
Cdd:PRK14850 644 -TNNLVDSWFVG----IDGKQVVIT------WIGRDNNHTTKLYGSSGAM 682
|
|
| PRK13481 |
PRK13481 |
glycosyltransferase; Provisional |
70-269 |
2.78e-22 |
|
glycosyltransferase; Provisional
Pssm-ID: 184078 [Multi-domain] Cd Length: 232 Bit Score: 96.41 E-value: 2.78e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 70 ANGDVLASFfDQNREPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAALGQVV-GNSGGGSTLTQQYVKQVRIqi 148
Cdd:PRK13481 33 DNVDELRKI-ENKSSFVSADNMPEYVKGAFISMEDERFYKHHGFDLKGTTRALFSTISdRDVQGGSTITQQVVKNYFY-- 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 149 aqDNgdtkaEQeaqapTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDGAYGVQAAAKHYFGV---- 224
Cdd:PRK13481 110 --DN-----ER-----SFTRKVKELFVAHRVEKQYSK---------NEILSFYLNNIYFGDNQYTLEGAANHYFGTtvnk 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 756352522 225 ---NAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMLK 269
Cdd:PRK13481 169 nstTMSHITVLQSAILASKVNAPSVYNINDMSENFTQRVSTNLEKMKQ 216
|
|
| PRK11240 |
PRK11240 |
penicillin-binding protein 1C; Provisional |
60-293 |
2.08e-19 |
|
penicillin-binding protein 1C; Provisional
Pssm-ID: 183049 [Multi-domain] Cd Length: 772 Bit Score: 93.23 E-value: 2.08e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 60 HQAENSQILLA-NGDVLASFFDQN---REPVGLDQISPLMQKAQMAIEDHRFYDHGAVDAQGILRAAL-----GQVVGns 130
Cdd:PRK11240 35 HEVNPARVVVAeDGTPLWRFADADgiwRYPVTIEDVSPRYLEALINYEDRWFWKHPGVNPFSVARAAWqdltsGRVIS-- 112
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 131 gGGSTLTQQYVKQVriqiaqdngdtkaeqEAQAPTMSRKILEMRYAVALEQELTKqkgslkaakDAILENYLNIAYYGDG 210
Cdd:PRK11240 113 -GGSTLTMQVARLL---------------DPHPRTFGGKIRQLWRALQLEWHLSK---------REILTLYLNRAPFGGT 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 211 AYGVQAAAKHYFGVNAKDLDLEQSAMLAGLVQSPSDTDPVNHPDAAIARRNVVLEQMlkwDQEGTWftgspqlTSDQVQQ 290
Cdd:PRK11240 168 LQGIGAASWAYLGKSPANLSYAEAALLAVLPQAPSRLRPDRWPERAEAARNKVLERM---AEQGVW-------SAEQVKE 237
|
...
gi 756352522 291 AKD 293
Cdd:PRK11240 238 SRE 240
|
|
| pbp2_mrdA |
TIGR03423 |
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 ... |
380-638 |
6.79e-19 |
|
penicillin-binding protein 2; Members of this protein family are penicillin-binding protein 2 (PBP-2), a protein whose gene (designated pbpA or mrdA) generally is found next to the gene for RodA, a protein required for rod (bacillus) shape in many bacteria. PBP-2 acts as a transpeptidase for cell elongation (hence, rod-shape). [Cell envelope, Biosynthesis and degradation of murein sacculus and peptidoglycan]
Pssm-ID: 274573 [Multi-domain] Cd Length: 592 Bit Score: 91.05 E-value: 6.79e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 380 AVMTDPKTGLIKAMAqSKP-------VMGTNTdagETY-----------YNYAV-GQdmggaegYQAGSTFKAFVAAAAI 440
Cdd:TIGR03423 251 VVVMDPRTGEILAMV-STPsfdpnlfVDGISS---KDYkallndpdrplLNRAIqGV-------YPPGSTFKPVVALAAL 319
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 441 SEGFI-PSQTYYnapatknwegttfknCDGNFVFKsgdGQGWTVSNSWKTGNMNMLTGMGASVNNYFVALERDAGIcssI 519
Cdd:TIGR03423 320 EEGVItPETRIY---------------CPGYFQLG---GRRFRCWKRGGHGRVDLRKAIEESCDVYFYQLALRLGI---D 378
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756352522 520 KMAETVGM----QLADSNTPMENYQNVPS-------F--------TL------GALNVTPISMAEAYATFANRGIHCDPV 574
Cdd:TIGR03423 379 KIAEYAKRfgfgQKTGIDLPGEKSGLVPSrewkrkrFgqpwypgdTLnvsigqGYVLVTPLQLAVATAALANGGKLYKPH 458
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 756352522 575 ILASAKTADGNSLPVPPGNCKQV--IDPTVADGVNLVMQQVLKT-GGTGVASKVPGNYDQAGKTGTA 638
Cdd:TIGR03423 459 LVKSIEDPDGGVVRRTEPEVLRPlpISPENLDVVREGMRDVVNGpGGTARRARLGLPYKMAGKTGTA 525
|
|
| |
