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Conserved domains on  [gi|756140999|ref|NP_001291849|]
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small ribosomal subunit protein eS8 [Ailuropoda melanoleuca]

Protein Classification

40S ribosomal protein S8( domain architecture ID 11488120)

40S ribosomal protein S8 is a component of the small ribosomal subunit (SSU) that binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules

Gene Ontology:  GO:0003735|GO:0006412|GO:0015935
PubMed:  24524803

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
PTZ00148 PTZ00148
40S ribosomal protein S8; Provisional
1-206 9.05e-116

40S ribosomal protein S8; Provisional


:

Pssm-ID: 240292 [Multi-domain]  Cd Length: 205  Bit Score: 328.10  E-value: 9.05e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   1 MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIID 80
Cdd:PTZ00148   1 MGISRDSRHKRRLTGGKMPIHRKKRKFELGRQPANTKLGSKRVRPVRCRGGNFKFRALRLDTGNFSWGSQGIAKKTRILD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  81 VVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKltPEEEEILNKKRSKKIQKKYDERKKNAKISS 160
Cdd:PTZ00148  81 VVYNASNNELVRTKTLVKNAIVQIDAAPFKQWYAKHYGIDLGKKKKYK--KEEENKKAKKKSESLVAKLEVRKKNHKIDK 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 756140999 161 LLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARK 206
Cdd:PTZ00148 159 ALLEQFQSGRLLARISSRPGQSGRADGYILEGKELEFYLKKLEKKK 204
 
Name Accession Description Interval E-value
PTZ00148 PTZ00148
40S ribosomal protein S8; Provisional
1-206 9.05e-116

40S ribosomal protein S8; Provisional


Pssm-ID: 240292 [Multi-domain]  Cd Length: 205  Bit Score: 328.10  E-value: 9.05e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   1 MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIID 80
Cdd:PTZ00148   1 MGISRDSRHKRRLTGGKMPIHRKKRKFELGRQPANTKLGSKRVRPVRCRGGNFKFRALRLDTGNFSWGSQGIAKKTRILD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  81 VVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKltPEEEEILNKKRSKKIQKKYDERKKNAKISS 160
Cdd:PTZ00148  81 VVYNASNNELVRTKTLVKNAIVQIDAAPFKQWYAKHYGIDLGKKKKYK--KEEENKKAKKKSESLVAKLEVRKKNHKIDK 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 756140999 161 LLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARK 206
Cdd:PTZ00148 159 ALLEQFQSGRLLARISSRPGQSGRADGYILEGKELEFYLKKLEKKK 204
Ribosomal_S8e pfam01201
Ribosomal protein S8e;
5-190 5.83e-72

Ribosomal protein S8e;


Pssm-ID: 460110  Cd Length: 133  Bit Score: 214.28  E-value: 5.83e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999    5 RDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYN 84
Cdd:pfam01201   1 RQGRHKRKLTGGKAKLFRKKRKYELGRQPANTKLGEERVKVVRVRGGNRKVRALRLKKANVTHPSEGVTKKLKILGVVYN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   85 ASNNELVRTKTLVKNCIVLIDSTPyrqwyeshyalplgrkkgakltpeeeeilnkkrskkiqkkyderkknakisslLEE 164
Cdd:pfam01201  81 PSNPEYVRRNILTKGAIIETDVGP-----------------------------------------------------LGL 107
                         170       180
                  ....*....|....*....|....*.
gi 756140999  165 QFQQGKLLACIASRPGQCGRADGYVL 190
Cdd:pfam01201 108 VFQGGKLYARVTSRPGQDGCVNAVLL 133
Ribosomal_S8e_like cd11380
Eukaryotic/archaeal ribosomal protein S8e and similar proteins; This family contains the ...
5-190 4.61e-63

Eukaryotic/archaeal ribosomal protein S8e and similar proteins; This family contains the eukaryotic/archaeal ribosomal protein S8, a component of the small ribosomal subunits, as well as the NSA2 gene product.


Pssm-ID: 211392  Cd Length: 138  Bit Score: 191.96  E-value: 4.61e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   5 RDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIG-PRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVY 83
Cdd:cd11380    1 PQGKHKRKATGGKFKVVRKKRKYELGRKPANTKLGgERFTRKVRVRGGNIKPRALRLDKANVSHPELGKTKKLKILGVKK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  84 NASNNELVRTKTLVKNCIVLIDSTPYRQWYeshyalplgrkkgakltpeeeeilnkkrskkiqkkyderkknakissllE 163
Cdd:cd11380   81 NPSNNEYVRRGVITKGTIIETDVSPLGLVT-------------------------------------------------E 111
                        170       180
                 ....*....|....*....|....*..
gi 756140999 164 EQFQQGKLLACIASRPGQCGRADGYVL 190
Cdd:cd11380  112 EGKVVWGGYAQVTSRPGQDGCVNAVLL 138
eS8 TIGR00307
ribosomal protein eS8; Archaeal and eukaryotic ribosomal protein S8. This model could easily ...
1-107 8.03e-34

ribosomal protein eS8; Archaeal and eukaryotic ribosomal protein S8. This model could easily have been split into two models, one for eukaryotic S8 and one for archaeal S8; eukaryotic forms invariably have in insert of about 80 residues that archaeal forms of S8 do not. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 129407  Cd Length: 127  Bit Score: 117.25  E-value: 8.03e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999    1 MGISRDNwHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIID 80
Cdd:TIGR00307   1 MGIWQGR-SRRKPTGGKYRQARKKRKYELGREPAETKIGERRIKKVRTRGGNKKVRLLRDETANVSDPETGKVKKVEIAG 79
                          90       100
                  ....*....|....*....|....*..
gi 756140999   81 VVYNASNNELVRTKTLVKNCIVLIDST 107
Cdd:TIGR00307  80 VVENPANNHYVRRNVITKGAIVETDIG 106
RPS8A COG2007
Ribosomal protein S8E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S8E ...
10-102 6.04e-27

Ribosomal protein S8E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S8E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441610  Cd Length: 127  Bit Score: 99.49  E-value: 6.04e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  10 KRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNE 89
Cdd:COG2007    9 TRKPTGGRKRPARKKRKYELGREPTETKVGEEKRKIVRVRGGNTKVRLLRANYANVADPKTGKVKKAKILNVVENPANPN 88
                         90
                 ....*....|...
gi 756140999  90 LVRTKTLVKNCIV 102
Cdd:COG2007   89 YVRRNIITKGAII 101
 
Name Accession Description Interval E-value
PTZ00148 PTZ00148
40S ribosomal protein S8; Provisional
1-206 9.05e-116

40S ribosomal protein S8; Provisional


Pssm-ID: 240292 [Multi-domain]  Cd Length: 205  Bit Score: 328.10  E-value: 9.05e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   1 MGISRDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIID 80
Cdd:PTZ00148   1 MGISRDSRHKRRLTGGKMPIHRKKRKFELGRQPANTKLGSKRVRPVRCRGGNFKFRALRLDTGNFSWGSQGIAKKTRILD 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  81 VVYNASNNELVRTKTLVKNCIVLIDSTPYRQWYESHYALPLGRKKGAKltPEEEEILNKKRSKKIQKKYDERKKNAKISS 160
Cdd:PTZ00148  81 VVYNASNNELVRTKTLVKNAIVQIDAAPFKQWYAKHYGIDLGKKKKYK--KEEENKKAKKKSESLVAKLEVRKKNHKIDK 158
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 756140999 161 LLEEQFQQGKLLACIASRPGQCGRADGYVLEGKELEFYLRKIKARK 206
Cdd:PTZ00148 159 ALLEQFQSGRLLARISSRPGQSGRADGYILEGKELEFYLKKLEKKK 204
Ribosomal_S8e pfam01201
Ribosomal protein S8e;
5-190 5.83e-72

Ribosomal protein S8e;


Pssm-ID: 460110  Cd Length: 133  Bit Score: 214.28  E-value: 5.83e-72
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999    5 RDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYN 84
Cdd:pfam01201   1 RQGRHKRKLTGGKAKLFRKKRKYELGRQPANTKLGEERVKVVRVRGGNRKVRALRLKKANVTHPSEGVTKKLKILGVVYN 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   85 ASNNELVRTKTLVKNCIVLIDSTPyrqwyeshyalplgrkkgakltpeeeeilnkkrskkiqkkyderkknakisslLEE 164
Cdd:pfam01201  81 PSNPEYVRRNILTKGAIIETDVGP-----------------------------------------------------LGL 107
                         170       180
                  ....*....|....*....|....*.
gi 756140999  165 QFQQGKLLACIASRPGQCGRADGYVL 190
Cdd:pfam01201 108 VFQGGKLYARVTSRPGQDGCVNAVLL 133
Ribosomal_S8e_like cd11380
Eukaryotic/archaeal ribosomal protein S8e and similar proteins; This family contains the ...
5-190 4.61e-63

Eukaryotic/archaeal ribosomal protein S8e and similar proteins; This family contains the eukaryotic/archaeal ribosomal protein S8, a component of the small ribosomal subunits, as well as the NSA2 gene product.


Pssm-ID: 211392  Cd Length: 138  Bit Score: 191.96  E-value: 4.61e-63
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   5 RDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIG-PRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVY 83
Cdd:cd11380    1 PQGKHKRKATGGKFKVVRKKRKYELGRKPANTKLGgERFTRKVRVRGGNIKPRALRLDKANVSHPELGKTKKLKILGVKK 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  84 NASNNELVRTKTLVKNCIVLIDSTPYRQWYeshyalplgrkkgakltpeeeeilnkkrskkiqkkyderkknakissllE 163
Cdd:cd11380   81 NPSNNEYVRRGVITKGTIIETDVSPLGLVT-------------------------------------------------E 111
                        170       180
                 ....*....|....*....|....*..
gi 756140999 164 EQFQQGKLLACIASRPGQCGRADGYVL 190
Cdd:cd11380  112 EGKVVWGGYAQVTSRPGQDGCVNAVLL 138
Ribosomal_S8e cd11382
Eukaryotic/archaeal ribosomal protein S8e (RPS8); The eukaryotic/archaeal ribosomal protein S8 ...
5-190 4.07e-60

Eukaryotic/archaeal ribosomal protein S8e (RPS8); The eukaryotic/archaeal ribosomal protein S8 is a component of the small (40S in eukaryotes, 30S in archaea) ribosomal subunits and interacts tightly with 18S rRNA (16S rRNA in archaea, presumably).


Pssm-ID: 211394  Cd Length: 122  Bit Score: 183.85  E-value: 4.07e-60
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999   5 RDNWHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYN 84
Cdd:cd11382    1 RQGRHKRKKTGGKRRPYRKKRKYELGRPPANTKLGERRVKTVRVRGGNTKVRALRLDTGNVSWPSEGKTKKVKILDVVYN 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  85 ASNNELVRTKTLVKNCIVLIDstpyrqwyeshyalplgrkkgakltpeeeeilnkkrskkiqkkyderkknakissllee 164
Cdd:cd11382   81 PANNELVRRNTLTKGAIIETD----------------------------------------------------------- 101
                        170       180
                 ....*....|....*....|....*.
gi 756140999 165 qfqqgKLLACIASRPGQCGRADGYVL 190
Cdd:cd11382  102 -----RGLARVTSRPGQDGVVNGVLL 122
eS8 TIGR00307
ribosomal protein eS8; Archaeal and eukaryotic ribosomal protein S8. This model could easily ...
1-107 8.03e-34

ribosomal protein eS8; Archaeal and eukaryotic ribosomal protein S8. This model could easily have been split into two models, one for eukaryotic S8 and one for archaeal S8; eukaryotic forms invariably have in insert of about 80 residues that archaeal forms of S8 do not. [Protein synthesis, Ribosomal proteins: synthesis and modification]


Pssm-ID: 129407  Cd Length: 127  Bit Score: 117.25  E-value: 8.03e-34
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999    1 MGISRDNwHKRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIID 80
Cdd:TIGR00307   1 MGIWQGR-SRRKPTGGKYRQARKKRKYELGREPAETKIGERRIKKVRTRGGNKKVRLLRDETANVSDPETGKVKKVEIAG 79
                          90       100
                  ....*....|....*....|....*..
gi 756140999   81 VVYNASNNELVRTKTLVKNCIVLIDST 107
Cdd:TIGR00307  80 VVENPANNHYVRRNVITKGAIVETDIG 106
RPS8A COG2007
Ribosomal protein S8E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S8E ...
10-102 6.04e-27

Ribosomal protein S8E [Translation, ribosomal structure and biogenesis]; Ribosomal protein S8E is part of the Pathway/BioSystem: Archaeal ribosomal proteins


Pssm-ID: 441610  Cd Length: 127  Bit Score: 99.49  E-value: 6.04e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  10 KRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNE 89
Cdd:COG2007    9 TRKPTGGRKRPARKKRKYELGREPTETKVGEEKRKIVRVRGGNTKVRLLRANYANVADPKTGKVKKAKILNVVENPANPN 88
                         90
                 ....*....|...
gi 756140999  90 LVRTKTLVKNCIV 102
Cdd:COG2007   89 YVRRNIITKGAII 101
PRK04049 PRK04049
30S ribosomal protein S8e; Validated
10-102 5.93e-25

30S ribosomal protein S8e; Validated


Pssm-ID: 235214  Cd Length: 127  Bit Score: 94.51  E-value: 5.93e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 756140999  10 KRRKTGGKRKPYHKKRKYELGRPAANTKIGPRRIHTVRVRGGNKKYRALRLDVGNFSWGSECCTRKTRIIDVVYNASNNE 89
Cdd:PRK04049   9 LRKPTGGRKRPARKKRKYELGREPTETTVGEDKRKIVRVRGGNRKVRLLRANYANVADPKTGKTKKVKILTVVENPANPH 88
                         90
                 ....*....|...
gi 756140999  90 LVRTKTLVKNCIV 102
Cdd:PRK04049  89 YARRNIITKGAII 101
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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