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Conserved domains on  [gi|7549742|ref|NP_036850|]
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cystatin-related protein 1 precursor [Rattus norvegicus]

Protein Classification

CY domain-containing protein( domain architecture ID 10036424)

CY domain-containing protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 41-135 1.71e-13

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


:

Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 63.26  E-value: 1.71e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7549742   41 IDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIW-GFGEIEMVKTKCRKIDSDFYKCSFQREFYNLKRTPGETMY 119
Cdd:cd00042   8 ANDPEVQELADFAVAEYNKKSNDKYLEFFKVLSAKSQVVaGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEEGKKKFCTA 87

                        90
                ....*....|....*.
gi 7549742  120 YISLPGSVRCRKLLSK 135
Cdd:cd00042  88 KVWEKPWENFKELLSF 103
 
Name Accession Description Interval E-value
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 41-135 1.71e-13

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 63.26  E-value: 1.71e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7549742   41 IDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIW-GFGEIEMVKTKCRKIDSDFYKCSFQREFYNLKRTPGETMY 119
Cdd:cd00042   8 ANDPEVQELADFAVAEYNKKSNDKYLEFFKVLSAKSQVVaGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEEGKKKFCTA 87

                        90
                ....*....|....*.
gi 7549742  120 YISLPGSVRCRKLLSK 135
Cdd:cd00042  88 KVWEKPWENFKELLSF 103
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 31-174 3.77e-13

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 62.45  E-value: 3.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7549742      31 RGMEIFEKNFIDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIWGFGEIEMVKTKCRKIDsdfykcsfqrefynl 110
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETN--------------- 65

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7549742     111 krtpgetmyyislpgsvrCRKLLSKLDNCPFEEQTEqlkrEICYFVVYPDYIEQNIHAVRFDCY 174
Cdd:smart00043  66 ------------------CKKLSVDLENCPFLDQGE----KFCTAKVWEKPWENKIKLVEFKCT 107
 
Name Accession Description Interval E-value
CY cd00042
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 41-135 1.71e-13

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 238002 [Multi-domain]  Cd Length: 105  Bit Score: 63.26  E-value: 1.71e-13
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7549742   41 IDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIW-GFGEIEMVKTKCRKIDSDFYKCSFQREFYNLKRTPGETMY 119
Cdd:cd00042   8 ANDPEVQELADFAVAEYNKKSNDKYLEFFKVLSAKSQVVaGTNYYITVEAGDTNCKKSSVPLDCPDCKLLEEGKKKFCTA 87

                        90
                ....*....|....*.
gi 7549742  120 YISLPGSVRCRKLLSK 135
Cdd:cd00042  88 KVWEKPWENFKELLSF 103
CY smart00043
Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly ...
 31-174 3.77e-13

Cystatin-like domain; Cystatins are a family of cysteine protease inhibitors that occur mainly as single domain proteins. However some extracellular proteins such as kininogen, His-rich glycoprotein and fetuin also contain these domains.


Pssm-ID: 214484  Cd Length: 107  Bit Score: 62.45  E-value: 3.77e-13
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7549742      31 RGMEIFEKNFIDKNKLKDVYDVFKYLYNTHSADTYLSNIKNESFTMNIWGFGEIEMVKTKCRKIDsdfykcsfqrefynl 110
Cdd:smart00043   1 LCLGGPSDVPPNDPEVQEAADFAVAEYNKKSNDKYELRVIKVVSAKSQVVAGTNYYLKVEVGETN--------------- 65

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7549742     111 krtpgetmyyislpgsvrCRKLLSKLDNCPFEEQTEqlkrEICYFVVYPDYIEQNIHAVRFDCY 174
Cdd:smart00043  66 ------------------CKKLSVDLENCPFLDQGE----KFCTAKVWEKPWENKIKLVEFKCT 107
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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