|
Name |
Accession |
Description |
Interval |
E-value |
| metN |
PRK11153 |
DL-methionine transporter ATP-binding subunit; Provisional |
1-343 |
0e+00 |
|
DL-methionine transporter ATP-binding subunit; Provisional
Pssm-ID: 236863 [Multi-domain] Cd Length: 343 Bit Score: 625.67 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:PRK11153 1 MIELKNISKVFPQGGRTIHALNNVSLHIPAGEIFGVIGASGAGKSTLIRCINLLERPTSGRVLVDGQDLTALSEKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:PRK11153 81 RRQIGMIFQHFNLLSSRTVFDNVALPLELAGTPKAEIKARVTELLELVGLSDKADRYPAQLSGGQKQRVAIARALASNPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDF 240
Cdd:PRK11153 161 VLLCDEATSALDPATTRSILELLKDINRELGLTIVLITHEMDVVKRICDRVAVIDAGRLVEQGTVSEVFSHPKHPLTREF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 241 IHSTIHLEVPQEYQDRLSAERVANSYPLVKLGFTGSTVDTPLISEASRRFNIDISILSADIEYAGGVKFGFLLAELFGDE 320
Cdd:PRK11153 241 IQSTLHLDLPEDYLARLQAEPTTGSGPLLRLEFTGESVDAPLLSETARRFGVDFNILSGQIDYIGGVKFGSLLVELTGDP 320
|
330 340
....*....|....*....|...
gi 754651031 321 AQCEATQQFLIDNHIQLEVMGYV 343
Cdd:PRK11153 321 GDIQAAIAYLQEHGVKVEVLGYV 343
|
|
| AbcC |
COG1135 |
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism]; |
1-341 |
0e+00 |
|
ABC-type methionine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440750 [Multi-domain] Cd Length: 339 Bit Score: 583.19 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG1135 1 MIELENLSKTFPTKGGPVTALDDVSLTIEKGEIFGIIGYSGAGKSTLIRCINLLERPTSGSVLVDGVDLTALSERELRAA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG1135 81 RRKIGMIFQHFNLLSSRTVAENVALPLEIAGVPKAEIRKRVAELLELVGLSDKADAYPSQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDF 240
Cdd:COG1135 161 VLLCDEATSALDPETTRSILDLLKDINRELGLTIVLITHEMDVVRRICDRVAVLENGRIVEQGPVLDVFANPQSELTRRF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 241 IHSTIHLEVPQEYQDRLSAErvANSYPLVKLGFTGSTVDTPLISEASRRFNIDISILSADIEYAGGVKFGFLLAELFGDE 320
Cdd:COG1135 241 LPTVLNDELPEELLARLREA--AGGGRLVRLTFVGESADEPLLSELARRFGVDVNILSGGIEEIQGTPVGRLIVELEGDD 318
|
330 340
....*....|....*....|.
gi 754651031 321 AQCEATQQFLIDNHIQLEVMG 341
Cdd:COG1135 319 AAIDAALAYLREQGVVVEVLG 339
|
|
| ABC_MetN |
TIGR02314 |
D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding ... |
1-343 |
0e+00 |
|
D-methionine ABC transporter, ATP-binding protein; Members of this family are the ATP-binding protein of the D-methionine ABC transporter complex. Known members belong to the Proteobacteria.
Pssm-ID: 131367 [Multi-domain] Cd Length: 343 Bit Score: 529.07 E-value: 0e+00
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:TIGR02314 1 MIKLSNITKVFHQGTKTIQALNNVSLHVPAGQIYGVIGASGAGKSTLIRCVNLLERPTSGSVIVDGQDLTTLSNSELTKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:TIGR02314 81 RRQIGMIFQHFNLLSSRTVFGNVALPLELDNTPKDEIKRKVTELLALVGLGDKHDSYPSNLSGGQKQRVAIARALASNPK 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDF 240
Cdd:TIGR02314 161 VLLCDEATSALDPATTQSILELLKEINRRLGLTILLITHEMDVVKRICDCVAVISNGELIEQGTVSEIFSHPKTPLAQKF 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 241 IHSTIHLEVPQEYQDRLSAERVANSYPLVKLGFTGSTVDTPLISEASRRFNIDISILSADIEYAGGVKFGFLLAELFGDE 320
Cdd:TIGR02314 241 IRSTLHLSIPEDYQERLQATPFADSVPMVRLEFTGQTVDAPLLSQTARRFNVDNSILSSQMDYAGGVKFGIMLAEMHGTQ 320
|
330 340
....*....|....*....|...
gi 754651031 321 AQCEATQQFLIDNHIQLEVMGYV 343
Cdd:TIGR02314 321 QDTQAAIAYLQEHNVKVEVLGYV 343
|
|
| ABC_MetN_methionine_transporter |
cd03258 |
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ... |
1-233 |
2.84e-148 |
|
ATP-binding cassette domain of methionine transporter; MetN (also known as YusC) is an ABC-type transporter encoded by metN of the metNPQ operon in Bacillus subtilis that is involved in methionine transport. Other members of this system include the MetP permease and the MetQ substrate binding protein. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213225 [Multi-domain] Cd Length: 233 Bit Score: 416.98 E-value: 2.84e-148
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:cd03258 1 MIELKNVSKVFGDTGGKVTALKDVSLSVPKGEIFGIIGRSGAGKSTLIRCINGLERPTSGSVLVDGTDLTLLSGKELRKA 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:cd03258 81 RRRIGMIFQHFNLLSSRTVFENVALPLEIAGVPKAEIEERVLELLELVGLEDKADAYPAQLSGGQKQRVGIARALANNPK 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:cd03258 161 VLLCDEATSALDPETTQSILALLRDINRELGLTIVLITHEMEVVKRICDRVAVMEKGEVVEEGTVEEVFANPQ 233
|
|
| LolD |
COG1136 |
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis]; |
1-222 |
1.29e-100 |
|
ABC-type lipoprotein export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440751 [Multi-domain] Cd Length: 227 Bit Score: 296.18 E-value: 1.29e-100
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG1136 4 LLELRNLTKSYGTGEGEVTALRGVSLSIEAGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVLIDGQDISSLSERELARL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQ-IGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:COG1136 84 RRRhIGFVFQFFNLLPELTALENVALPLLLAGVSRKERRERARELLERVGLGDRLDHRPSQLSGGQQQRVAIARALVNRP 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKgICDDVAIISDGSLIEQ 222
Cdd:COG1136 164 KLILADEPTGNLDSKTGEEVLELLRELNRELGTTIVMVTHDPELAA-RADRVIRLRDGRIVSD 225
|
|
| GlnQ |
COG1126 |
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and ... |
1-242 |
1.05e-99 |
|
ABC-type polar amino acid transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 440743 [Multi-domain] Cd Length: 239 Bit Score: 294.21 E-value: 1.05e-99
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPERELTLA 80
Cdd:COG1126 1 MIEIENLHKSFGD----LEVLKGISLDVEKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTITVDGED-LTDSKKDINKL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAF-PLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:COG1126 76 RRKVGMVFQQFNLFPHLTVLENVTLaPIKVKKMSKAEAEERAMELLERVGLADKADAYPAQLSGGQQQRVAIARALAMEP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARD 239
Cdd:COG1126 156 KVMLFDEPTSALDPELVGEVLDVMRDL-AKEGMTMVVVTHEMGFAREVADRVVFMDGGRIVEEGPPEEFFENPQHERTRA 234
|
...
gi 754651031 240 FIH 242
Cdd:COG1126 235 FLS 237
|
|
| MlaF |
COG1127 |
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall ... |
1-241 |
3.74e-93 |
|
ATPase subunit MlaF of the ABC-type intermembrane phospholipid transporter Mla [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440744 [Multi-domain] Cd Length: 241 Bit Score: 277.63 E-value: 3.74e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG1127 5 MIEVRNLTKSFGD----RVVLDGVSLDVPRGEILAIIGGSGSGKSVLLKLIIGLLRPDSGEILVDGQDITGLSEKELYEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPL-ELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:COG1127 81 RRRIGMLFQGGALFDSLTVFENVAFPLrEHTDLSEAEIRELVLEKLELVGLPGAADKMPSELSGGMRKRVALARALALDP 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFsNAKTQLARD 239
Cdd:COG1127 161 EILLYDEPTAGLDPITSAVIDELIRELRDELGLTSVVVTHDLDSAFAIADRVAVLADGKIIAEGTPEELL-ASDDPWVRQ 239
|
..
gi 754651031 240 FI 241
Cdd:COG1127 240 FL 241
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-238 |
7.32e-93 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 286.03 E-value: 7.32e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYG-KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTL 79
Cdd:COG1123 260 LLEVRNLSKRYPvRGKGGVRAVDDVSLTLRRGETLGLVGESGSGKSTLARLLLGLLRPTSGSILFDGKDLTKLSRRSLRE 339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQH-FNLLSSR-TVFANIAFPLELAGW-SKSQIRARVDELLALVGLEAR-AHAYPSELSGGQKQRVAIARAL 155
Cdd:COG1123 340 LRRRVQMVFQDpYSSLNPRmTVGDIIAEPLRLHGLlSRAERRERVAELLERVGLPPDlADRYPHELSGGQRQRVAIARAL 419
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQ 235
Cdd:COG1123 420 ALEPKLLILDEPTSALDVSVQAQILNLLRDLQRELGLTYLFISHDLAVVRYIADRVAVMYDGRIVEDGPTEEVFANPQHP 499
|
...
gi 754651031 236 LAR 238
Cdd:COG1123 500 YTR 502
|
|
| ABC_MJ0796_LolCDE_FtsE |
cd03255 |
ATP-binding cassette domain of the transporters involved in export of lipoprotein and ... |
2-219 |
9.82e-93 |
|
ATP-binding cassette domain of the transporters involved in export of lipoprotein and macrolide, and Cell division ATP-binding protein FtsE; This family is comprised of MJ0796 ATP-binding cassette, macrolide-specific ABC-type efflux carrier (MacAB), and proteins involved in cell division (FtsE), and release of lipoproteins from the cytoplasmic membrane (LolCDE). They are clustered together phylogenetically. MacAB is an exporter that confers resistance to macrolides, while the LolCDE system is not a transporter at all. The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages. The LolCDE complex catalyzes the release of lipoproteins from the cytoplasmic membrane prior to their targeting to the outer membrane.
Pssm-ID: 213222 [Multi-domain] Cd Length: 218 Bit Score: 275.52 E-value: 9.82e-93
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR 81
Cdd:cd03255 1 IELKNLSKTYGGGGEKVQALKGVSLSIEKGEFVAIVGPSGSGKSTLLNILGGLDRPTSGEVRVDGTDISKLSEKELAAFR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 R-QIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:cd03255 81 RrHIGFVFQSFNLLPDLTALENVELPLLLAGVPKKERRERAEELLERVGLGDRLNHYPSELSGGQQQRVAIARALANDPK 160
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKgICDDVAIISDGSL 219
Cdd:cd03255 161 IILADEPTGNLDSETGKEVMELLRELNKEAGTTIVVVTHDPELAE-YADRIIELRDGKI 218
|
|
| FtsE |
COG2884 |
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning]; |
1-224 |
1.73e-92 |
|
Cell division ATPase FtsE [Cell cycle control, cell division, chromosome partitioning];
Pssm-ID: 442130 [Multi-domain] Cd Length: 223 Bit Score: 275.39 E-value: 1.73e-92
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG2884 1 MIRFENVSKRYPGG---REALSDVSLEIEKGEFVFLTGPSGAGKSTLLKLLYGEERPTSGQVLVNGQDLSRLKRREIPYL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG2884 78 RRRIGVVFQDFRLLPDRTVYENVALPLRVTGKSRKEIRRRVREVLDLVGLSDKAKALPHELSGGEQQRVAIARALVNRPE 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:COG2884 158 LLLADEPTGNLDPETSWEIMELLEEIN-RRGTTVLIATHDLELVDRMPKRVLELEDGRLVRDEA 220
|
|
| ABC_HisP_GlnQ |
cd03262 |
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ... |
2-217 |
8.78e-83 |
|
ATP-binding cassette domain of the histidine and glutamine transporters; HisP and GlnQ are the ATP-binding components of the bacterial periplasmic histidine and glutamine permeases, respectively. Histidine permease is a multi-subunit complex containing the HisQ and HisM integral membrane subunits and two copies of HisP. HisP has properties intermediate between those of integral and peripheral membrane proteins and is accessible from both sides of the membrane, presumably by its interaction with HisQ and HisM. The two HisP subunits form a homodimer within the complex. The domain structure of the amino acid uptake systems is typical for prokaryotic extracellular solute binding protein-dependent uptake systems. All of the amino acid uptake systems also have at least one, and in a few cases, two extracellular solute binding proteins located in the periplasm of Gram-negative bacteria, or attached to the cell membrane of Gram-positive bacteria. The best-studied member of the PAAT (polar amino acid transport) family is the HisJQMP system of S. typhimurium, where HisJ is the extracellular solute binding proteins and HisP is the ABC protein.
Pssm-ID: 213229 [Multi-domain] Cd Length: 213 Bit Score: 250.14 E-value: 8.78e-83
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlPERELTLAR 81
Cdd:cd03262 1 IEIKNLHKSFGD----FHVLKGIDLTVKKGEVVVIIGPSGSGKSTLLRCINLLEEPDSGTIIIDGLKLTD-DKKNINELR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAF-PLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:cd03262 76 QKVGMVFQQFNLFPHLTVLENITLaPIKVKGMSKAEAEERALELLEKVGLADKADAYPAQLSGGQQQRVAIARALAMNPK 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd03262 156 VMLFDEPTSALDPELVGEVLDVMKDL-AEEGMTMVVVTHEMGFAREVADRVIFMDDG 211
|
|
| ABC_Carb_Solutes_like |
cd03259 |
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is ... |
2-223 |
1.09e-82 |
|
ATP-binding cassette domain of the carbohydrate and solute transporters-like; This family is comprised of proteins involved in the transport of apparently unrelated solutes and proteins specific for di- and oligosaccharides and polyols. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213226 [Multi-domain] Cd Length: 213 Bit Score: 249.74 E-value: 1.09e-82
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlaR 81
Cdd:cd03259 1 LELKGLSKTYGS----VRALDDLSLTVEPGEFLALLGPSGCGKTTLLRLIAGLERPDSGEILIDGRDVTGVPPE-----R 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03259 72 RNIGMVFQDYALFPHLTVAENIAFGLKLRGVPKAEIRARVRELLELVGLEGLLNRYPHELSGGQQQRVALARALAREPSL 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03259 152 LLLDEPLSALDAKLREELREELKELQRELGITTIYVTHDQEEALALADRIAVMNEGRIVQVG 213
|
|
| DppF |
COG1124 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-250 |
1.12e-81 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440741 [Multi-domain] Cd Length: 248 Bit Score: 248.56 E-value: 1.12e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtla 80
Cdd:COG1124 1 MLEVRNLSVSYGQGGRRVPVLKDVSLEVAPGESFGLVGESGSGKSTLLRALAGLERPWSGEVTFDGRPVTRRRRKAF--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFnlLSS----RTVFANIAFPLELAGwsKSQIRARVDELLALVGLEAR-AHAYPSELSGGQKQRVAIARAL 155
Cdd:COG1124 78 RRRVQMVFQDP--YASlhprHTVDRILAEPLRIHG--LPDREERIAELLEQVGLPPSfLDRYPHQLSGGQRQRVAIARAL 153
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQ 235
Cdd:COG1124 154 ILEPELLLLDEPTSALDVSVQAEILNLLKDLREERGLTYLFVSHDLAVVAHLCDRVAVMQNGRIVEELTVADLLAGPKHP 233
|
250
....*....|....*
gi 754651031 236 LARDFIHSTIHLEVP 250
Cdd:COG1124 234 YTRELLAASLAFERA 248
|
|
| EcfA2 |
COG1122 |
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and ... |
2-234 |
4.42e-81 |
|
Energy-coupling factor transporter ATP-binding protein EcfA2 [Inorganic ion transport and metabolism, General function prediction only];
Pssm-ID: 440739 [Multi-domain] Cd Length: 230 Bit Score: 246.48 E-value: 4.42e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:COG1122 1 IELENLSFSYPGG---TPALDDVSLSIEKGEFVAIIGPNGSGKSTLLRLLNGLLKPTSGEVLVDGKDITKKNLREL---R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG1122 75 RKVGLVFQNpDDQLFAPTVEEDVAFGPENLGLPREEIRERVEEALELVGLEHLADRPPHELSGGQKQRVAIAGVLAMEPE 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:COG1122 155 VLVLDEPTAGLDPRGRRELLELLKRLN-KEGKTVIIVTHDLDLVAELADRVIVLDDGRIVADGTPREVFSDYEL 227
|
|
| DppD |
COG0444 |
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid ... |
1-233 |
4.70e-81 |
|
ABC-type dipeptide/oligopeptide/nickel transport system, ATPase component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];
Pssm-ID: 440213 [Multi-domain] Cd Length: 320 Bit Score: 249.59 E-value: 4.70e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLERP--TEGQVIVDGQDLVALPEREL 77
Cdd:COG0444 1 LLEVRNLKVYFPTRRGVVKAVDGVSFDVRRGETLGLVGESGSGKSTLARAIlGLLPPPgiTSGEILFDGEDLLKLSEKEL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 78 TLAR-RQIGMIFQhfNLLSS----RTVFANIAFPLEL-AGWSKSQIRARVDELLALVGL---EARAHAYPSELSGGQKQR 148
Cdd:COG0444 81 RKIRgREIQMIFQ--DPMTSlnpvMTVGDQIAEPLRIhGGLSKAEARERAIELLERVGLpdpERRLDRYPHELSGGMRQR 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 149 VAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWF 228
Cdd:COG0444 159 VMIARALALEPKLLIADEPTTALDVTIQAQILNLLKDLQRELGLAILFITHDLGVVAEIADRVAVMYAGRIVEEGPVEEL 238
|
....*
gi 754651031 229 FSNAK 233
Cdd:COG0444 239 FENPR 243
|
|
| TauB |
COG1116 |
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion ... |
1-202 |
5.56e-81 |
|
ABC-type nitrate/sulfonate/bicarbonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440733 [Multi-domain] Cd Length: 260 Bit Score: 247.31 E-value: 5.56e-81
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGqdlvalpeRELTLA 80
Cdd:COG1116 7 ALELRGVSKRFPTGGGGVTALDDVSLTVAAGEFVALVGPSGCGKSTLLRLIAGLEKPTSGEVLVDG--------KPVTGP 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG1116 79 GPDRGVVFQEPALLPWLTVLDNVALGLELRGVPKAERRERARELLELVGLAGFEDAYPHQLSGGMRQRVAIARALANDPE 158
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD 202
Cdd:COG1116 159 VLLMDEPFGALDALTRERLQDELLRLWQETGKTVLFVTHDVD 200
|
|
| PhnC |
COG3638 |
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and ... |
1-220 |
1.42e-80 |
|
ABC-type phosphate/phosphonate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 442855 [Multi-domain] Cd Length: 249 Bit Score: 245.74 E-value: 1.42e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG3638 2 MLELRNLSKRYPGG---TPALDDVSLEIERGEFVALIGPSGAGKSTLLRCLNGLVEPTSGEILVDGQDVTALRGRALRRL 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANI--------AFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIA 152
Cdd:COG3638 79 RRRIGMIFQQFNLVPRLSVLTNVlagrlgrtSTWRSLLGLFPPEDRERALEALERVGLADKAYQRADQLSGGQQQRVAIA 158
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:COG3638 159 RALVQEPKLILADEPVASLDPKTARQVMDLLRRIAREDGITVVVNLHQVDLARRYADRIIGLRDGRVV 226
|
|
| ABC_NikE_OppD_transporters |
cd03257 |
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter ... |
1-223 |
1.87e-80 |
|
ATP-binding cassette domain of nickel/oligopeptides specific transporters; The ABC transporter subfamily specific for the transport of dipeptides, oligopeptides (OppD), and nickel (NikDE). The NikABCDE system of E. coli belongs to this family and is composed of the periplasmic binding protein NikA, two integral membrane components (NikB and NikC), and two ATPase (NikD and NikE). The NikABCDE transporter is synthesized under anaerobic conditions to meet the increased demand for nickel resulting from hydrogenase synthesis. The molecular mechanism of nickel uptake in many bacteria and most archaea is not known. Many other members of this ABC family are also involved in the uptake of dipeptides and oligopeptides. The oligopeptide transport system (Opp) is a five-component ABC transport composed of a membrane-anchored substrate binding proteins (SRP), OppA, two transmembrane proteins, OppB and OppC, and two ATP-binding domains, OppD and OppF.
Pssm-ID: 213224 [Multi-domain] Cd Length: 228 Bit Score: 244.72 E-value: 1.87e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:cd03257 1 LLEVKNLSVSFPTGGGSVKALDDVSFSIKKGETLGLVGESGSGKSTLARAILGLLKPTSGSIIFDGKDLLKLSRRLRKIR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQhfNLLSS----RTVFANIAFPLELAG--WSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIAR 153
Cdd:cd03257 81 RKEIQMVFQ--DPMSSlnprMTIGEQIAEPLRIHGklSKKEARKEAVLLLLVGVGLpEEVLNRYPHELSGGQRQRVAIAR 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 154 ALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03257 159 ALALNPKLLIADEPTSALDVSVQAQILDLLKKLQEELGLTLLFITHDLGVVAKIADRVAVMYAGKIVEEG 228
|
|
| PotA |
COG3842 |
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport ... |
1-222 |
2.26e-80 |
|
ABC-type Fe3+/spermidine/putrescine transport systems, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443052 [Multi-domain] Cd Length: 353 Bit Score: 248.86 E-value: 2.26e-80
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlA 80
Cdd:COG3842 5 ALELENVSKRYG----DVTALDDVSLSIEPGEFVALLGPSGCGKTTLLRMIAGFETPDSGRILLDGRDVTGLPP-----E 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG3842 76 KRNVGMVFQDYALFPHLTVAENVAFGLRMRGVPKAEIRARVAELLELVGLEGLADRYPHQLSGGQQQRVALARALAPEPR 155
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSlIEQ 222
Cdd:COG3842 156 VLLLDEPLSALDAKLREEMREELRRLQRELGITFIYVTHDQEEALALADRIAVMNDGR-IEQ 216
|
|
| ABC_Org_Solvent_Resistant |
cd03261 |
ATP-binding cassette transport system involved in resistance to organic solvents; ABC ... |
2-223 |
1.46e-79 |
|
ATP-binding cassette transport system involved in resistance to organic solvents; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213228 [Multi-domain] Cd Length: 235 Bit Score: 242.79 E-value: 1.46e-79
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR 81
Cdd:cd03261 1 IELRGLTKSFGGR----TVLKGVDLDVRRGEILAIIGPSGSGKSTLLRLIVGLLRPDSGEVLIDGEDISGLSEAELYRLR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPL-ELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:cd03261 77 RRMGMLFQSGALFDSLTVFENVAFPLrEHTRLSEEEIREIVLEKLEAVGLRGAEDLYPAELSGGMKKRVALARALALDPE 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03261 157 LLLYDEPTAGLDPIASGVIDDLIRSLKKELGLTSIMVTHDLDTAFAIADRIAVLYDGKIVAEG 219
|
|
| CcmA |
COG1131 |
ABC-type multidrug transport system, ATPase component [Defense mechanisms]; |
2-226 |
2.19e-77 |
|
ABC-type multidrug transport system, ATPase component [Defense mechanisms];
Pssm-ID: 440746 [Multi-domain] Cd Length: 236 Bit Score: 237.27 E-value: 2.19e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlAR 81
Cdd:COG1131 1 IEVRGLTKRYGD----KTALDGVSLTVEPGEIFGLLGPNGAGKTTTIRMLLGLLRPTSGEVRVLGEDVARDPAE----VR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:COG1131 73 RRIGYVPQEPALYPDLTVRENLRFFARLYGLPRKEARERIDELLELFGLTDAADRKVGTLSGGMKQRLGLALALLHDPEL 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG1131 153 LILDEPTSGLDPEARRELWELLRELA-AEGKTVLLSTHYLEEAERLCDRVAIIDKGRIVADGTPD 216
|
|
| ABC_NrtD_SsuB_transporters |
cd03293 |
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ... |
2-202 |
4.92e-77 |
|
ATP-binding cassette domain of the nitrate and sulfonate transporters; NrtD and SsuB are the ATP-binding subunits of the bacterial ABC-type nitrate and sulfonate transport systems, respectively. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213260 [Multi-domain] Cd Length: 220 Bit Score: 235.83 E-value: 4.92e-77
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlpereltlAR 81
Cdd:cd03293 1 LEVRNVSKTYGGGGGAVTALEDISLSVEEGEFVALVGPSGCGKSTLLRIIAGLERPTSGEVLVDGEPVTG--------PG 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03293 73 PDRGYVFQQDALLPWLTVLDNVALGLELQGVPKAEARERAEELLELVGLSGFENAYPHQLSGGMRQRVALARALAVDPDV 152
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD 202
Cdd:cd03293 153 LLLDEPFSALDALTREQLQEELLDIWRETGKTVLLVTHDID 193
|
|
| ABC_PhnC_transporter |
cd03256 |
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; ... |
2-217 |
3.41e-75 |
|
ATP-binding cassette domain of the binding protein-dependent phosphonate transport system; Phosphonates are a class of organophosphorus compounds characterized by a chemically stable carbon-to-phosphorus (C-P) bond. Phosphonates are widespread among naturally occurring compounds in all kingdoms of wildlife, but only prokaryotic microorganisms are able to cleave this bond. Certain bacteria such as E. coli can use alkylphosphonates as a phosphorus source. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213223 [Multi-domain] Cd Length: 241 Bit Score: 231.69 E-value: 3.41e-75
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR 81
Cdd:cd03256 1 IEVENLSKTYPNG---KKALKDVSLSINPGEFVALIGPSGAGKSTLLRCLNGLVEPTSGSVLIDGTDINKLKGKALRQLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPL--------ELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIAR 153
Cdd:cd03256 78 RQIGMIFQQFNLIERLSVLENVLSGRlgrrstwrSLFGLFPKEEKQRALAALERVGLLDKAYQRADQLSGGQQQRVAIAR 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 154 ALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd03256 158 ALMQQPKLILADEPVASLDPASSRQVMDLLKRINREEGITVIVSLHQVDLAREYADRIVGLKDG 221
|
|
| ABC_Pro_Gly_Betaine |
cd03294 |
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This ... |
2-241 |
1.73e-74 |
|
ATP-binding cassette domain of the osmoprotectant proline/glycine betaine uptake system; This family comprises the glycine betaine/L-proline ATP binding subunit in bacteria and its equivalents in archaea. This transport system belong to the larger ATP-Binding Cassette (ABC) transporter superfamily. The characteristic feature of these transporters is the obligatory coupling of ATP hydrolysis to substrate translocation. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213261 [Multi-domain] Cd Length: 269 Bit Score: 230.99 E-value: 1.73e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYG--------------------KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQ 61
Cdd:cd03294 1 IKIKGLYKIFGknpqkafkllakgkskeeilKKTGQTVGVNDVSLDVREGEIFVIMGLSGSGKSTLLRCINRLIEPTSGK 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 62 VIVDGQDLVALPERELT-LARRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSE 140
Cdd:cd03294 81 VLIDGQDIAAMSRKELReLRRKKISMVFQSFALLPHRTVLENVAFGLEVQGVPRAEREERAAEALELVGLEGWEHKYPDE 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 141 LSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:cd03294 161 LSGGMQQRVGLARALAVDPDILLMDEAFSALDPLIRREMQDELLRLQAELQKTIVFITHDLDEALRLGDRIAIMKDGRLV 240
|
250 260
....*....|....*....|.
gi 754651031 221 EQGEVAWFFSNAKTQLARDFI 241
Cdd:cd03294 241 QVGTPEEILTNPANDYVREFF 261
|
|
| ABC_cobalt_CbiO_domain1 |
cd03225 |
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ... |
3-217 |
9.40e-74 |
|
First domain of the ATP-binding cassette component of cobalt transport system; Domain I of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. This ABC transport system of the CbiMNQO family is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most of cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213192 [Multi-domain] Cd Length: 211 Bit Score: 226.96 E-value: 9.40e-74
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 3 KLNGLNKVYGKGSDAvhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRR 82
Cdd:cd03225 1 ELKNLSFSYPDGARP--ALDDISLTIKKGEFVLIVGPNGSGKSTLLRLLNGLLGPTSGEVLVDGKDLTKLSLKEL---RR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIGMIFQHFNL-LSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03225 76 KVGLVFQNPDDqFFGPTVEEEVAFGLENLGLPEEEIEERVEEALELVGLEGLRDRSPFTLSGGQKQRVAIAGVLAMDPDI 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd03225 156 LLLDEPTAGLDPAGRRELLELLKKLK-AEGKTIIIVTHDLDLLLELADRVIVLEDG 210
|
|
| GsiA |
COG1123 |
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain ... |
1-268 |
2.75e-73 |
|
ABC-type glutathione transport system ATPase component, contains duplicated ATPase domain [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 440740 [Multi-domain] Cd Length: 514 Bit Score: 235.57 E-value: 2.75e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPT---EGQVIVDGQDLVALPEREL 77
Cdd:COG1123 4 LLEVRDLSVRYPGG--DVPAVDGVSLTIAPGETVALVGESGSGKSTLALALMGLLPHGgriSGEVLLDGRDLLELSEALR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 78 tlaRRQIGMIFQHF-NLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:COG1123 82 ---GRRIGMVFQDPmTQLNPVTVGDQIAEALENLGLSRAEARARVLELLEAVGLERRLDRYPHQLSGGQRQRVAIAMALA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQL 236
Cdd:COG1123 159 LDPDLLIADEPTTALDVTTQAEILDLLRELQRERGTTVLLITHDLGVVAEIADRVVVMDDGRIVEDGPPEEILAAPQALA 238
|
250 260 270
....*....|....*....|....*....|....
gi 754651031 237 ARDFIHSTIHLEVPQEYQDR--LSAERVANSYPL 268
Cdd:COG1123 239 AVPRLGAARGRAAPAAAAAEplLEVRNLSKRYPV 272
|
|
| AppF |
COG4608 |
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism]; ... |
2-231 |
7.12e-73 |
|
ABC-type oligopeptide transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443658 [Multi-domain] Cd Length: 329 Bit Score: 228.85 E-value: 7.12e-73
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVY-------GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPE 74
Cdd:COG4608 8 LEVRDLKKHFpvrgglfGRTVGVVKAVDGVSFDIRRGETLGLVGESGCGKSTLGRLLLRLEEPTSGEILFDGQDITGLSG 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 75 RELTLARRQIGMIFQH-FNLLSSR-TVFANIAFPLELAG-WSKSQIRARVDELLALVGLEAR-AHAYPSELSGGQKQRVA 150
Cdd:COG4608 88 RELRPLRRRMQMVFQDpYASLNPRmTVGDIIAEPLRIHGlASKAERRERVAELLELVGLRPEhADRYPHEFSGGQRQRIG 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 151 IARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFS 230
Cdd:COG4608 168 IARALALNPKLIVCDEPVSALDVSIQAQVLNLLEDLQDELGLTYLFISHDLSVVRHISDRVAVMYLGKIVEIAPRDELYA 247
|
.
gi 754651031 231 N 231
Cdd:COG4608 248 R 248
|
|
| ABC_PstB_phosphate_transporter |
cd03260 |
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of ... |
2-225 |
3.35e-72 |
|
ATP-binding cassette domain of the phosphate transport system; Phosphate uptake is of fundamental importance in the cell physiology of bacteria because phosphate is required as a nutrient. The Pst system of E. coli comprises four distinct subunits encoded by the pstS, pstA, pstB, and pstC genes. The PstS protein is a phosphate-binding protein located in the periplasmic space. PstA and PstC are hydrophobic and they form the transmembrane portion of the Pst system. PstB is the catalytic subunit, which couples the energy of ATP hydrolysis to the import of phosphate across cellular membranes through the Pst system, often referred as ABC-protein. PstB belongs to one of the largest superfamilies of proteins characterized by a highly conserved adenosine triphosphate (ATP) binding cassette (ABC), which is also a nucleotide binding domain (NBD).
Pssm-ID: 213227 [Multi-domain] Cd Length: 227 Bit Score: 223.60 E-value: 3.35e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL-----ERPTEGQVIVDGQDLVALPERE 76
Cdd:cd03260 1 IELRDLNVYYGDK----HALKDISLDIPKGEITALIGPSGCGKSTLLRLLNRLndlipGAPDEGEVLLDGKDIYDLDVDV 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLaRRQIGMIFQHFNLLSSrTVFANIAFPLELAG-WSKSQIRARVDELLALVGL--EARAHAYPSELSGGQKQRVAIAR 153
Cdd:cd03260 77 LEL-RRRVGMVFQKPNPFPG-SIYDNVAYGLRLHGiKLKEELDERVEEALRKAALwdEVKDRLHALGLSGGQQQRLCLAR 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 154 ALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlgLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:cd03260 155 ALANEPEVLLLDEPTSALDPISTAKIEELIAELKKE--YTIVIVTHNMQQAARVADRTAFLLNGRLVEFGPT 224
|
|
| CysA |
COG1118 |
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and ... |
2-224 |
4.85e-72 |
|
ABC-type sulfate/molybdate transport systems, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440735 [Multi-domain] Cd Length: 348 Bit Score: 227.34 E-value: 4.85e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDL-VALPEREltla 80
Cdd:COG1118 3 IEVRNISKRFG----SFTLLDDVSLEIASGELVALLGPSGSGKTTLLRIIAGLETPDSGRIVLNGRDLfTNLPPRE---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG1118 75 -RRVGFVFQHYALFPHMTVAENIAFGLRVRPPSKAEIRARVEELLELVQLEGLADRYPSQLSGGQRQRVALARALAVEPE 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:COG1118 154 VLLLDEPFGALDAKVRKELRRWLRRLHDELGGTTVFVTHDQEEALELADRVVVMNQGRIEQVGT 217
|
|
| ProV |
COG4175 |
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and ... |
1-223 |
8.20e-72 |
|
ABC-type proline/glycine betaine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443334 [Multi-domain] Cd Length: 389 Bit Score: 228.06 E-value: 8.20e-72
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHAL--------------------RDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEG 60
Cdd:COG4175 3 KIEVRNLYKIFGKRPERALKLldqgkskdeilektgqtvgvNDASFDVEEGEIFVIMGLSGSGKSTLVRCLNRLIEPTAG 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 61 QVIVDGQDLVALPERELT-LARRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPS 139
Cdd:COG4175 83 EVLIDGEDITKLSKKELReLRRKKMSMVFQHFALLPHRTVLENVAFGLEIQGVPKAERRERAREALELVGLAGWEDSYPD 162
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 140 ELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD-VVKgICDDVAIISDGS 218
Cdd:COG4175 163 ELSGGMQQRVGLARALATDPDILLMDEAFSALDPLIRREMQDELLELQAKLKKTIVFITHDLDeALR-LGDRIAIMKDGR 241
|
....*
gi 754651031 219 LIEQG 223
Cdd:COG4175 242 IVQIG 246
|
|
| ABC_phnC |
TIGR02315 |
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of ... |
1-223 |
7.02e-71 |
|
phosphonate ABC transporter, ATP-binding protein; Phosphonates are a class of phosphorus-containing organic compound with a stable direct C-P bond rather than a C-O-P linkage. A number of bacterial species have operons, typically about 14 genes in size, with genes for ATP-dependent transport of phosphonates, degradation, and regulation of the expression of the system. Members of this protein family are the ATP-binding cassette component of tripartite ABC transporters of phosphonates. [Transport and binding proteins, Anions]
Pssm-ID: 131368 [Multi-domain] Cd Length: 243 Bit Score: 221.02 E-value: 7.02e-71
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:TIGR02315 1 MLEVENLSKVYPNG---KQALKNINLNINPGEFVAIIGPSGAGKSTLLRCINRLVEPSSGSILLEGTDITKLRGKKLRKL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANI--------AFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIA 152
Cdd:TIGR02315 78 RRRIGMIFQHYNLIERLTVLENVlhgrlgykPTWRSLLGRFSEEDKERALSALERVGLADKAYQRADQLSGGQQQRVAIA 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:TIGR02315 158 RALAQQPDLILADEPIASLDPKTSKQVMDYLKRINKEDGITVIINLHQVDLAKKYADRIVGLKAGEIVFDG 228
|
|
| ABC_Class3 |
cd03229 |
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is ... |
2-217 |
5.56e-70 |
|
ATP-binding cassette domain of the binding protein-dependent transport systems; This class is comprised of all BPD (Binding Protein Dependent) systems that are largely represented in archaea and eubacteria and are primarily involved in scavenging solutes from the environment. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213196 [Multi-domain] Cd Length: 178 Bit Score: 216.28 E-value: 5.56e-70
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPERELTLAR 81
Cdd:cd03229 1 LELKNVSKRYGQ----KTVLNDVSLNIEAGEIVALLGPSGSGKSTLLRCIAGLEEPDSGSILIDGED-LTDLEDELPPLR 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPlelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPAPKV 161
Cdd:cd03229 76 RRIGMVFQDFALFPHLTVLENIALG----------------------------------LSGGQQQRVALARALAMDPDV 121
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd03229 122 LLLDEPTSALDPITRREVRALLKSLQAQLGITVVLVTHDLDEAARLADRVVVLRDG 177
|
|
| ECF_ATPase_2 |
TIGR04521 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-251 |
6.05e-69 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the downstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275314 [Multi-domain] Cd Length: 277 Bit Score: 216.93 E-value: 6.05e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:TIGR04521 1 IKLKNVSYIYQPGTPfEKKALDDVSLTIEDGEFVAIIGHTGSGKSTLIQHLNGLLKPTSGTVTIDGRDITAKKKKKLKDL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQhF--NLLSSRTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARALA 156
Cdd:TIGR04521 81 RKKVGLVFQ-FpeHQLFEETVYKDIAFgPKNL-GLSEEEAEERVKEALELVGLdEEYLERSPFELSGGQMRRVAIAGVLA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAktql 236
Cdd:TIGR04521 159 MEPEVLILDEPTAGLDPKGRKEILDLFKRLHKEKGLTVILVTHSMEDVAEYADRVIVMHKGKIVLDGTPREVFSDV---- 234
|
250
....*....|....*
gi 754651031 237 arDFIHStIHLEVPQ 251
Cdd:TIGR04521 235 --DELEK-IGLDVPE 246
|
|
| glnQ |
PRK09493 |
glutamine ABC transporter ATP-binding protein GlnQ; |
1-241 |
9.13e-69 |
|
glutamine ABC transporter ATP-binding protein GlnQ;
Pssm-ID: 181906 [Multi-domain] Cd Length: 240 Bit Score: 215.34 E-value: 9.13e-69
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPERELTLA 80
Cdd:PRK09493 1 MIEFKNVSKHFGP----TQVLHNIDLNIDQGEVVVIIGPSGSGKSTLLRCINKLEEITSGDLIVDGLK-VNDPKVDERLI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAF-PLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK09493 76 RQEAGMVFQQFYLFPHLTALENVMFgPLRVRGASKEEAEKQARELLAKVGLAERAHHYPSELSGGQQQRVAIARALAVKP 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARD 239
Cdd:PRK09493 156 KLMLFDEPTSALDPELRHEVLKVMQDL-AEEGMTMVIVTHEIGFAEKVASRLIFIDKGRIAEDGDPQVLIKNPPSQRLQE 234
|
..
gi 754651031 240 FI 241
Cdd:PRK09493 235 FL 236
|
|
| YbbA |
COG4181 |
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase ... |
1-221 |
5.50e-68 |
|
Predicted ABC-type transport system involved in lysophospholipase L1 biosynthesis, ATPase component [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443338 [Multi-domain] Cd Length: 233 Bit Score: 213.06 E-value: 5.50e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:COG4181 8 IIELRGLTKTVGTGAGELTILKGISLEVEAGESVAIVGASGSGKSTLLGLLAGLDRPTSGTVRLAGQDLFALDEDARARL 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQ-IGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARvdELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:COG4181 88 RARhVGFVFQSFQLLPTLTALENVMLPLELAGRRDARARAR--ALLERVGLGHRLDHYPAQLSGGEQQRVALARAFATEP 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIE 221
Cdd:COG4181 166 AILFADEPTGNLDAATGEQIIDLLFELNRERGTTLVLVTHDPALAAR-CDRVLRLRAGRLVE 226
|
|
| ABC_OpuCA_Osmoprotection |
cd03295 |
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding ... |
2-241 |
8.13e-68 |
|
ATP-binding cassette domain of the osmoprotectant transporter; OpuCA is a the ATP binding component of a bacterial solute transporter that serves a protective role to cells growing in a hyperosmolar environment. ABC (ATP-binding cassette) transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition, to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213262 [Multi-domain] Cd Length: 242 Bit Score: 212.93 E-value: 8.13e-68
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVhalRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:cd03295 1 IEFENVTKRYGGGKKAV---NNLNLEIAKGEFLVLIGPSGSGKTTTMKMINRLIEPTSGEIFIDGEDIREQDPVEL---R 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEAR--AHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:cd03295 75 RKIGYVIQQIGLFPHMTVEENIALVPKLLKWPKEKIRERADELLALVGLDPAefADRYPHELSGGQQQRVGVARALAADP 154
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARD 239
Cdd:cd03295 155 PLLLMDEPFGALDPITRDQLQEEFKRLQQELGKTIVFVTHDIDEAFRLADRIAIMKNGEIVQVGTPDEILRSPANDFVAE 234
|
..
gi 754651031 240 FI 241
Cdd:cd03295 235 FV 236
|
|
| ABC_PotA_N |
cd03300 |
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and ... |
2-222 |
3.54e-67 |
|
ATP-binding cassette domain of the polyamine transporter; PotA is an ABC-type transporter and the ATPase component of the spermidine/putrescine-preferential uptake system consisting of PotA, -B, -C, and -D. PotA has two domains with the N-terminal domain containing the ATPase activity and the residues required for homodimerization with PotA and heterdimerization with PotB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213267 [Multi-domain] Cd Length: 232 Bit Score: 210.94 E-value: 3.54e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlAR 81
Cdd:cd03300 1 IELENVSKFYGGF----VALDGVSLDIKEGEFFTLLGPSGCGKTTLLRLIAGFETPTSGEILLDGKDITNLPP-----HK 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03300 72 RPVNTVFQNYALFPHLTVFENIAFGLRLKKLPKAEIKERVAEALDLVQLEGYANRKPSQLSGGQQQRVAIARALVNEPKV 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSlIEQ 222
Cdd:cd03300 152 LLLDEPLGALDLKLRKDMQLELKRLQKELGITFVFVTHDQEEALTMSDRIAVMNKGK-IQQ 211
|
|
| HisP |
COG4598 |
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism]; |
1-246 |
7.74e-67 |
|
ABC-type histidine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443652 [Multi-domain] Cd Length: 259 Bit Score: 211.20 E-value: 7.74e-67
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ----------DLV 70
Cdd:COG4598 8 ALEVRDLHKSFG----DLEVLKGVSLTARKGDVISIIGSSGSGKSTFLRCINLLETPDSGEIRVGGEeirlkpdrdgELV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 71 ALPERELTLARRQIGMIFQHFNLLSSRTVFAN-IAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRV 149
Cdd:COG4598 84 PADRRQLQRIRTRLGMVFQSFNLWSHMTVLENvIEAPVHVLGRPKAEAIERAEALLAKVGLADKRDAYPAHLSGGQQQRA 163
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSIL----SLLKEinvklGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:COG4598 164 AIARALAMEPEVMLFDEPTSALDPELVGEVLkvmrDLAEE-----GRTMLVVTHEMGFARDVSSHVVFLHQGRIEEQGPP 238
|
250 260
....*....|....*....|.
gi 754651031 226 AWFFSNAKTQLARDFIHSTIH 246
Cdd:COG4598 239 AEVFGNPKSERLRQFLSSSLK 259
|
|
| ABC_FtsE |
cd03292 |
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where ... |
2-219 |
1.00e-66 |
|
Cell division ATP-binding protein FtsE; The FtsEX complex resembles an ABC transporter, where FtsE is the ATPase and the membrane subunit FtsX resembles a permease subunit. But rather than transporting any substrate, the complex acts in cell division by undergoing conformational changes that alter the activity of cell wall hydrolases located outside the plasma membrane. The complex is widely conserved in bacteria, but also extremely divergent in sequence between different lineages
Pssm-ID: 213259 [Multi-domain] Cd Length: 214 Bit Score: 209.19 E-value: 1.00e-66
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR 81
Cdd:cd03292 1 IEFINVTKTYPNG---TAALDGINISISAGEFVFLVGPSGAGKSTLLKLIYKEELPTSGTIRVNGQDVSDLRGRAIPYLR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03292 78 RKIGVVFQDFRLLPDRNVYENVAFALEVTGVPPREIRKRVPAALELVGLSHKHRALPAELSGGEQQRVAIARAIVNSPTI 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:cd03292 158 LIADEPTGNLDPDTTWEIMNLLKKIN-KAGTTVVVATHAKELVDTTRHRVIALERGKL 214
|
|
| MalK |
COG3839 |
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism]; ... |
1-222 |
1.44e-65 |
|
ABC-type sugar transport system, ATPase component MalK [Carbohydrate transport and metabolism];
Pssm-ID: 443050 [Multi-domain] Cd Length: 352 Bit Score: 210.70 E-value: 1.44e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltla 80
Cdd:COG3839 3 SLELENVSKSYGG----VEALKDIDLDIEDGEFLVLLGPSGCGKSTLLRMIAGLEDPTSGEILIGGRDVTDLPPKD---- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG3839 75 -RNIAMVFQSYALYPHMTVYENIAFPLKLRKVPKAEIDRRVREAAELLGLEDLLDRKPKQLSGGQRQRVALGRALVREPK 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 161 VLLCDEATSALDPQ---TTRsilSLLKEINVKLGLTILLITHE----MdvvkGICDDVAIISDGSlIEQ 222
Cdd:COG3839 154 VFLLDEPLSNLDAKlrvEMR---AEIKRLHRRLGTTTIYVTHDqveaM----TLADRIAVMNDGR-IQQ 214
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
12-234 |
3.30e-65 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 214.93 E-value: 3.30e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 12 GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLerPTEGQVIVDGQDLVALPERELTLARRQIGMIFQH 90
Cdd:COG4172 293 RRTVGHVKAVDGVSLTLRRGETLGLVGESGSGKSTLGLALlRLI--PSEGEIRFDGQDLDGLSRRALRPLRRRMQVVFQD 370
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 -FNLLSSR-TVFANIAFPLEL--AGWSKSQIRARVDELLALVGLEARA-HAYPSELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:COG4172 371 pFGSLSPRmTVGQIIAEGLRVhgPGLSAAERRARVAEALEEVGLDPAArHRYPHEFSGGQRQRIAIARALILEPKLLVLD 450
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 166 EATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:COG4172 451 EPTSALDVSVQAQILDLLRDLQREHGLAYLFISHDLAVVRALAHRVMVMKDGKVVEQGPTEQVFDAPQH 519
|
|
| NatA |
COG4555 |
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, ... |
1-226 |
5.91e-65 |
|
ABC-type Na+ transport system, ATPase component NatA [Energy production and conversion, Inorganic ion transport and metabolism];
Pssm-ID: 443618 [Multi-domain] Cd Length: 243 Bit Score: 205.48 E-value: 5.91e-65
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlA 80
Cdd:COG4555 1 MIEVENLSKKYGK----VPALKDVSFTAKDGEITGLLGPNGAGKTTLLRMLAGLLKPDSGSILIDGEDVRKEPRE----A 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG4555 73 RRQIGVLPDERGLYDRLTVRENIRYFAELYGLFDEELKKRIEELIELLGLEEFLDRRVGELSTGMKKKVALARALVHDPK 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG4555 153 VLLLDEPTNGLDVMARRLLREILRALK-KEGKTVLFSSHIMQEVEALCDRVVILHKGKVVAQGSLD 217
|
|
| ECF_ATPase_1 |
TIGR04520 |
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette ... |
2-254 |
4.03e-64 |
|
energy-coupling factor transporter ATPase; Members of this family are ATP-binding cassette (ABC) proteins by homology, but belong to energy coupling factor (ECF) transport systems. The architecture in general is two ATPase subunits (or a double-length fusion protein), a T component, and a substrate capture (S) component that is highly variable, and may be interchangeable in genomes with only one T component. This model identifies many but not examples of the upstream member of the pair of ECF ATPases in Firmicutes and Mollicutes. [Transport and binding proteins, Unknown substrate]
Pssm-ID: 275313 [Multi-domain] Cd Length: 268 Bit Score: 204.20 E-value: 4.03e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvaLPERELTLAR 81
Cdd:TIGR04520 1 IEVENVSFSYPESE--KPALKNVSLSIEKGEFVAIIGHNGSGKSTLAKLLNGLLLPTSGKVTVDGLDT--LDEENLWEIR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:TIGR04520 77 KKVGMVFQNpDNQFVGATVEDDVAFGLENLGVPREEMRKRVDEALKLVGMEDFRDREPHLLSGGQKQRVAIAGVLAMRPD 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD-VVKgiCDDVAIISDGSLIEQGEVAWFFSNaktqlaRD 239
Cdd:TIGR04520 157 IIILDEATSMLDPKGRKEVLETIRKLNKEEGITVISITHDMEeAVL--ADRVIVMNKGKIVAEGTPREIFSQ------VE 228
|
250
....*....|....*
gi 754651031 240 FIHStIHLEVPQEYQ 254
Cdd:TIGR04520 229 LLKE-IGLDVPFITE 242
|
|
| artP |
PRK11124 |
arginine transporter ATP-binding subunit; Provisional |
2-235 |
5.42e-64 |
|
arginine transporter ATP-binding subunit; Provisional
Pssm-ID: 182980 [Multi-domain] Cd Length: 242 Bit Score: 203.32 E-value: 5.42e-64
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ--DLVALP-ERELT 78
Cdd:PRK11124 3 IQLNGINCFYG----AHQALFDITLDCPQGETLVLLGPSGAGKSSLLRVLNLLEMPRSGTLNIAGNhfDFSKTPsDKAIR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 LARRQIGMIFQHFNLLSSRTVFAN-IAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:PRK11124 79 ELRRNVGMVFQQYNLWPHLTVQQNlIEAPCRVLGLSKDQALARAEKLLERLRLKPYADRFPLHLSGGQQQRVAIARALMM 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEvAWFFSNAKTQ 235
Cdd:PRK11124 159 EPQVLLFDEPTAALDPEITAQIVSIIRELA-ETGITQVIVTHEVEVARKTASRVVYMENGHIVEQGD-ASCFTQPQTE 234
|
|
| PstB |
COG1117 |
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
2-241 |
1.13e-63 |
|
ABC-type phosphate transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440734 [Multi-domain] Cd Length: 258 Bit Score: 202.96 E-value: 1.13e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL--ERP---TEGQVIVDGQDLVAlPERE 76
Cdd:COG1117 12 IEVRNLNVYYGD----KQALKDINLDIPENKVTALIGPSGCGKSTLLRCLNRMndLIPgarVEGEILLDGEDIYD-PDVD 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQHFNLLSSrTVFANIAFPLELAGW-SKSQIRARVDELLALVGL----EARAHAYPSELSGGQKQRVAI 151
Cdd:COG1117 87 VVELRRRVGMVFQKPNPFPK-SIYDNVAYGLRLHGIkSKSELDEIVEESLRKAALwdevKDRLKKSALGLSGGQQQRLCI 165
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 152 ARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSN 231
Cdd:COG1117 166 ARALAVEPEVLLMDEPTSALDPISTAKIEELILEL--KKDYTIVIVTHNMQQAARVSDYTAFFYLGELVEFGPTEQIFTN 243
|
250
....*....|
gi 754651031 232 AKTQLARDFI 241
Cdd:COG1117 244 PKDKRTEDYI 253
|
|
| ArtP |
COG4161 |
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism]; |
2-235 |
1.48e-63 |
|
ABC-type arginine transport system, ATPase component [Amino acid transport and metabolism];
Pssm-ID: 443326 [Multi-domain] Cd Length: 242 Bit Score: 202.17 E-value: 1.48e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ--DLVALP-ERELT 78
Cdd:COG4161 3 IQLKNINCFYGS----HQALFDINLECPSGETLVLLGPSGAGKSSLLRVLNLLETPDSGQLNIAGHqfDFSQKPsEKAIR 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 LARRQIGMIFQHFNLLSSRTVFAN-IAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:COG4161 79 LLRQKVGMVFQQYNLWPHLTVMENlIEAPCKVLGLSKEQAREKAMKLLARLRLTDKADRFPLHLSGGQQQRVAIARALMM 158
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEvAWFFSNAKTQ 235
Cdd:COG4161 159 EPQVLLFDEPTAALDPEITAQVVEIIRELS-QTGITQVIVTHEVEFARKVASQVVYMEKGRIIEQGD-ASHFTQPQTE 234
|
|
| LivG |
COG0411 |
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid ... |
1-226 |
5.16e-63 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivG [Amino acid transport and metabolism];
Pssm-ID: 440180 [Multi-domain] Cd Length: 257 Bit Score: 201.04 E-value: 5.16e-63
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlA 80
Cdd:COG0411 4 LLEVRGLTKRFG----GLVAVDDVSLEVERGEIVGLIGPNGAGKTTLFNLITGFYRPTSGRILFDGRDITGLPPHRI--A 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIA---------------FPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQ 145
Cdd:COG0411 78 RLGIARTFQNPRLFPELTVLENVLvaaharlgrgllaalLRLPRARREEREARERAEELLERVGLADRADEPAGNLSYGQ 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 146 KQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:COG0411 158 QRRLEIARALATEPKLLLLDEPAAGLNPEETEELAELIRRLRDERGITILLIEHDMDLVMGLADRIVVLDFGRVIAEGTP 237
|
.
gi 754651031 226 A 226
Cdd:COG0411 238 A 238
|
|
| YejF |
COG4172 |
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites ... |
1-279 |
7.02e-62 |
|
ABC-type microcin C transport system, duplicated ATPase component YejF [Secondary metabolites biosynthesis, transport and catabolism];
Pssm-ID: 443332 [Multi-domain] Cd Length: 533 Bit Score: 206.07 E-value: 7.02e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKS-TLIRCVNLLERP---TEGQVIVDGQDLVALPERE 76
Cdd:COG4172 6 LLSVEDLSVAFGQGGGTVEAVKGVSFDIAAGETLALVGESGSGKSvTALSILRLLPDPaahPSGSILFDGQDLLGLSERE 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLAR-RQIGMIFQ---------HfnllssrTVFANIAFPLEL-AGWSKSQIRARVDELLALVGL---EARAHAYPSELS 142
Cdd:COG4172 86 LRRIRgNRIAMIFQepmtslnplH-------TIGKQIAEVLRLhRGLSGAAARARALELLERVGIpdpERRLDAYPHQLS 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 143 GGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQ 222
Cdd:COG4172 159 GGQRQRVMIAMALANEPDLLIADEPTTALDVTVQAQILDLLKDLQRELGMALLLITHDLGVVRRFADRVAVMRQGEIVEQ 238
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 223 GEVAWFFSNAKTQLARDFIHSTIHLEVPQEYQDR---LSAERVANSYPlVKLGFTGSTVD 279
Cdd:COG4172 239 GPTAELFAAPQHPYTRKLLAAEPRGDPRPVPPDApplLEARDLKVWFP-IKRGLFRRTVG 297
|
|
| ABC_Mj1267_LivG_branched |
cd03219 |
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ... |
2-223 |
9.14e-62 |
|
ATP-binding cassette component of branched chain amino acids transport system; The Mj1267/LivG ABC transporter subfamily is involved in the transport of the hydrophobic amino acids leucine, isoleucine and valine. MJ1267 is a branched-chain amino acid transporter with 29% similarity to both the LivF and LivG components of the E. coli branched-chain amino acid transporter. MJ1267 contains an insertion from residues 114 to 123 characteristic of LivG (Leucine-Isoleucine-Valine) homologs. The branched-chain amino acid transporter from E. coli comprises a heterodimer of ABCs (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ).
Pssm-ID: 213186 [Multi-domain] Cd Length: 236 Bit Score: 197.27 E-value: 9.14e-62
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlAR 81
Cdd:cd03219 1 LEVRGLTKRFG----GLVALDDVSFSVRPGEIHGLIGPNGAGKTTLFNLISGFLRPTSGSVLFDGEDITGLPPHEI--AR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIA--------FPLELAGWSKS--QIRARVDELLALVGLEARAHAYPSELSGGQKQRVAI 151
Cdd:cd03219 75 LGIGRTFQIPRLFPELTVLENVMvaaqartgSGLLLARARREerEARERAEELLERVGLADLADRPAGELSYGQQRRLEI 154
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 152 ARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03219 155 ARALATDPKLLLLDEPAAGLNPEETEELAELIRELR-ERGITVLLVEHDMDVVMSLADRVTVLDQGRVIAEG 225
|
|
| ABC_CysA_sulfate_importer |
cd03296 |
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex ... |
2-222 |
4.77e-61 |
|
ATP-binding cassette domain of the sulfate transporter; Part of the ABC transporter complex cysAWTP involved in sulfate import. Responsible for energy coupling to the transport system. The complex is composed of two ATP-binding proteins (cysA), two transmembrane proteins (cysT and cysW), and a solute-binding protein (cysP). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213263 [Multi-domain] Cd Length: 239 Bit Score: 195.64 E-value: 4.77e-61
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlar 81
Cdd:cd03296 3 IEVRNVSKRFG----DFVALDDVSLDIPSGELVALLGPSGSGKTTLLRLIAGLERPDSGTILFGGEDATDVPVQE----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLEL----AGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:cd03296 74 RNVGFVFQHYALFRHMTVFDNVAFGLRVkprsERPPEAEIRAKVHELLKLVQLDWLADRYPAQLSGGQRQRVALARALAV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSlIEQ 222
Cdd:cd03296 154 EPKVLLLDEPFGALDAKVRKELRRWLRRLHDELHVTTVFVTHDQEEALEVADRVVVMNKGR-IEQ 217
|
|
| ABC_MalK_N |
cd03301 |
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) ... |
2-222 |
2.68e-57 |
|
The N-terminal ATPase domain of the maltose transporter, MalK; ATP binding cassette (ABC) proteins function from bacteria to human, mediating the translocation of substances into and out of cells or organelles. ABC transporters contain two transmembrane-spanning domains (TMDs) or subunits and two nucleotide binding domains (NBDs) or subunits that couple transport to the hydrolysis of ATP. In the maltose transport system, the periplasmic maltose binding protein (MBP) stimulates the ATPase activity of the membrane-associated transporter, which consists of two transmembrane subunits, MalF and MalG, and two copies of the ATP binding subunit, MalK, and becomes tightly bound to the transporter in the catalytic transition state, ensuring that maltose is passed to the transporter as ATP is hydrolyzed.
Pssm-ID: 213268 [Multi-domain] Cd Length: 213 Bit Score: 185.15 E-value: 2.68e-57
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlar 81
Cdd:cd03301 1 VELENVTKRFGN----VTALDDLNLDIADGEFVVLLGPSGCGKTTTLRMIAGLEEPTSGRIYIGGRDVTDLPPKD----- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03301 72 RDIAMVFQNYALYPHMTVYDNIAFGLKLRKVPKDEIDERVREVAELLQIEHLLDRKPKQLSGGQRQRVALGRAIVREPKV 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSlIEQ 222
Cdd:cd03301 152 FLMDEPLSNLDAKLRVQMRAELKRLQQRLGTTTIYVTHDQVEAMTMADRIAVMNDGQ-IQQ 211
|
|
| PRK10619 |
PRK10619 |
histidine ABC transporter ATP-binding protein HisP; |
7-245 |
2.72e-56 |
|
histidine ABC transporter ATP-binding protein HisP;
Pssm-ID: 182592 [Multi-domain] Cd Length: 257 Bit Score: 184.02 E-value: 2.72e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 7 LNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQD----------LVALPERE 76
Cdd:PRK10619 11 LHKRYGEH----EVLKGVSLQANAGDVISIIGSSGSGKSTFLRCINFLEKPSEGSIVVNGQTinlvrdkdgqLKVADKNQ 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQHFNLLSSRTVFANI-AFPLELAGWSKSQIRARVDELLALVGLEARAHA-YPSELSGGQKQRVAIARA 154
Cdd:PRK10619 87 LRLLRTRLTMVFQHFNLWSHMTVLENVmEAPIQVLGLSKQEARERAVKYLAKVGIDERAQGkYPVHLSGGQQQRVSIARA 166
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:PRK10619 167 LAMEPEVLLFDEPTSALDPELVGEVLRIMQQL-AEEGKTMVVVTHEMGFARHVSSHVIFLHQGKIEEEGAPEQLFGNPQS 245
|
250
....*....|.
gi 754651031 235 QLARDFIHSTI 245
Cdd:PRK10619 246 PRLQQFLKGSL 256
|
|
| ABC_DR_subfamily_A |
cd03230 |
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily ... |
2-219 |
2.82e-56 |
|
ATP-binding cassette domain of the drug resistance transporter and related proteins, subfamily A; This family of ATP-binding proteins belongs to a multi-subunit transporter involved in drug resistance (BcrA and DrrA), nodulation, lipid transport, and lantibiotic immunity. In bacteria and archaea, these transporters usually include an ATP-binding protein and one or two integral membrane proteins. Eukaryotic systems of the ABCA subfamily display ABC domains that are quite similar to this family. The ATP-binding domain shows the highest similarity between all members of the ABC transporter family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213197 [Multi-domain] Cd Length: 173 Bit Score: 181.06 E-value: 2.82e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlAR 81
Cdd:cd03230 1 IEVRNLSKRYGKK----TALDDISLTVEKGEIYGLLGPNGAGKTTLIKIILGLLKPDSGEIKVLGKDIKKEPEE----VK 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIafplelagwsksqirarvdellalvglearahaypsELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03230 73 RRIGYLPEEPSLYENLTVRENL------------------------------------KLSGGMKQRLALAQALLHDPEL 116
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:cd03230 117 LILDEPTSGLDPESRREFWELLRELK-KEGKTILLSSHILEEAERLCDRVAILNNGRI 173
|
|
| FepC |
COG1120 |
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion ... |
1-226 |
3.71e-56 |
|
ABC-type cobalamin/Fe3+-siderophores transport system, ATPase component [Inorganic ion transport and metabolism, Coenzyme transport and metabolism];
Pssm-ID: 440737 [Multi-domain] Cd Length: 254 Bit Score: 183.32 E-value: 3.71e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtla 80
Cdd:COG1120 1 MLEAENLSVGYGG----RPVLDDVSLSLPPGEVTALLGPNGSGKSTLLRALAGLLKPSSGEVLLDGRDLASLSRREL--- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIA---FP-LELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:COG1120 74 ARRIAYVPQEPPAPFGLTVRELVAlgrYPhLGLFGRPSAEDREAVEEALERTGLEHLADRPVDELSGGERQRVLIARALA 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG1120 154 QEPPLLLLDEPTSHLDLAHQLEVLELLRRLARERGRTVVMVLHDLNLAARYADRLVLLKDGRIVAQGPPE 223
|
|
| ABC_subfamily_A |
cd03263 |
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily ... |
2-223 |
6.62e-56 |
|
ATP-binding cassette domain of the lipid transporters, subfamily A; The ABCA subfamily mediates the transport of a variety of lipid compounds. Mutations of members of ABCA subfamily are associated with human genetic diseases, such as, familial high-density lipoprotein (HDL) deficiency, neonatal surfactant deficiency, degenerative retinopathies, and congenital keratinization disorders. The ABCA1 protein is involved in disorders of cholesterol transport and high-density lipoprotein (HDL) biosynthesis. The ABCA4 (ABCR) protein transports vitamin A derivatives in the outer segments of photoreceptor cells, and therefore, performs a crucial step in the visual cycle. The ABCA genes are not present in yeast. However, evolutionary studies of ABCA genes indicate that they arose as transporters that subsequently duplicated and that certain sets of ABCA genes were lost in different eukaryotic lineages.
Pssm-ID: 213230 [Multi-domain] Cd Length: 220 Bit Score: 181.55 E-value: 6.62e-56
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValpeRELTLAR 81
Cdd:cd03263 1 LQIRNLTKTYKKGT--KPAVDDLSLNVYKGEIFGLLGHNGAGKTTTLKMLTGELRPTSGTAYINGYSIR----TDRKAAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03263 75 QSLGYCPQFDALFDELTVREHLRFYARLKGLPKSEIKEEVELLLRVLGLTDKANKRARTLSGGMKRKLSLAIALIGGPSV 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEinVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03263 155 LLLDEPTSGLDPASRRAIWDLILE--VRKGRSIILTTHSMDEAEALCDRIAIMSDGKLRCIG 214
|
|
| ZnuC |
COG1121 |
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism]; ... |
1-230 |
1.03e-55 |
|
ABC-type Mn2+/Zn2+ transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 440738 [Multi-domain] Cd Length: 245 Bit Score: 181.83 E-value: 1.03e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalperelTLA 80
Cdd:COG1121 6 AIELENLTVSYGG----RPVLEDVSLTIPPGEFVAIVGPNGAGKSTLLKAILGLLPPTSGTVRLFGKPP--------RRA 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLlssrtvfaNIAFPL---ELA-----------GWSKSQIRARVDELLALVGLEARAHAYPSELSGGQK 146
Cdd:COG1121 74 RRRIGYVPQRAEV--------DWDFPItvrDVVlmgrygrrglfRRPSRADREAVDEALERVGLEDLADRPIGELSGGQQ 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 147 QRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIIsDGSLIEQGEVA 226
Cdd:COG1121 146 QRVLLARALAQDPDLLLLDEPFAGVDAATEEALYELLRELR-REGKTILVVTHDLGAVREYFDRVLLL-NRGLVAHGPPE 223
|
....
gi 754651031 227 WFFS 230
Cdd:COG1121 224 EVLT 227
|
|
| PRK11264 |
PRK11264 |
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional |
1-241 |
5.05e-55 |
|
putative amino-acid ABC transporter ATP-binding protein YecC; Provisional
Pssm-ID: 183063 [Multi-domain] Cd Length: 250 Bit Score: 180.33 E-value: 5.05e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYgKGSDAVHAlrdVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIV-----DGQDLVALPER 75
Cdd:PRK11264 3 AIEVKNLVKKF-HGQTVLHG---IDLEVKPGEVVAIIGPSGSGKTTLLRCINLLEQPEAGTIRVgditiDTARSLSQQKG 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 76 ELTLARRQIGMIFQHFNLLSSRTVFAN-IAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:PRK11264 79 LIRQLRQHVGFVFQNFNLFPHRTVLENiIEGPVIVKGEPKEEATARARELLAKVGLAGKETSYPRRLSGGQQQRVAIARA 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:PRK11264 159 LAMRPEVILFDEPTSALDPELVGEVLNTIRQL-AQEKRTMVIVTHEMSFARDVADRAIFMDQGRIVEQGPAKALFADPQQ 237
|
....*..
gi 754651031 235 QLARDFI 241
Cdd:PRK11264 238 PRTRQFL 244
|
|
| ThiQ |
COG3840 |
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism]; |
1-241 |
7.65e-55 |
|
ABC-type thiamine transport system, ATPase component ThiQ [Coenzyme transport and metabolism];
Pssm-ID: 443051 [Multi-domain] Cd Length: 232 Bit Score: 179.18 E-value: 7.65e-55
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlA 80
Cdd:COG3840 1 MLRLDDLTYRYG------DFPLRFDLTIAAGERVAILGPSGAGKSTLLNLIAGFLPPDSGRILWNGQDLTALPP-----A 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAF---P-LELagwSKSQiRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:COG3840 70 ERPVSMLFQENNLFPHLTVAQNIGLglrPgLKL---TAEQ-RAQVEQALERVGLAGLLDRLPGQLSGGQRQRVALARCLV 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQL 236
Cdd:COG3840 146 RKRPILLLDEPFSALDPALRQEMLDLVDELCRERGLTVLMVTHDPEDAARIADRVLLVADGRIAADGPTAALLDGEPPPA 225
|
....*
gi 754651031 237 ARDFI 241
Cdd:COG3840 226 LAAYL 230
|
|
| ABC_ModC_like |
cd03299 |
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely ... |
2-241 |
1.17e-53 |
|
ATP-binding cassette domain similar to the molybdate transporter; Archaeal protein closely related to ModC. ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213266 [Multi-domain] Cd Length: 235 Bit Score: 176.37 E-value: 1.17e-53
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdavhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlaR 81
Cdd:cd03299 1 LKVENLSKDWKEFK-----LKNVSLEVERGDYFVILGPTGSGKSVLLETIAGFIKPDSGKILLNGKDITNLPPE-----K 70
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03299 71 RDISYVPQNYALFPHMTVYKNIAYGLKKRKVDKKEIERKVLEIAEMLGIDHLLNRKPETLSGGEQQRVAIARALVVNPKI 150
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFI 241
Cdd:cd03299 151 LLLDEPFSALDVRTKEKLREELKKIRKEFGVTVLHVTHDFEEAWALADKVAIMLNGKLIQVGKPEEVFKKPKNEFVAEFL 230
|
|
| potG |
PRK11607 |
putrescine ABC transporter ATP-binding subunit PotG; |
13-243 |
1.77e-52 |
|
putrescine ABC transporter ATP-binding subunit PotG;
Pssm-ID: 183226 [Multi-domain] Cd Length: 377 Bit Score: 177.72 E-value: 1.77e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 13 KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlaRRQIGMIFQHFN 92
Cdd:PRK11607 27 KSFDGQHAVDDVSLTIYKGEIFALLGASGCGKSTLLRMLAGFEQPTAGQIMLDGVDLSHVPPY-----QRPINMMFQSYA 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 LLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK11607 102 LFPHMTVEQNIAFGLKQDKLPKAEIASRVNEMLGLVHMQEFAKRKPHQLSGGQRQRVALARSLAKRPKLLLLDEPMGALD 181
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 173 PQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHS 243
Cdd:PRK11607 182 KKLRDRMQLEVVDILERVGVTCVMVTHDQEEAMTMAGRIAIMNRGKFVQIGEPEEIYEHPTTRYSAEFIGS 252
|
|
| PRK10908 |
PRK10908 |
cell division ATP-binding protein FtsE; |
1-219 |
1.82e-52 |
|
cell division ATP-binding protein FtsE;
Pssm-ID: 182829 [Multi-domain] Cd Length: 222 Bit Score: 172.75 E-value: 1.82e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:PRK10908 1 MIRFEHVSKAYLGGR---QALQGVTFHMRPGEMAFLTGHSGAGKSTLLKLICGIERPSAGKIWFSGHDITRLKNREVPFL 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:PRK10908 78 RRQIGMIFQDHHLLMDRTVYDNVAIPLIIAGASGDDIRRRVSAALDKVGLLDKAKNFPIQLSGGEQQRVGIARAVVNKPA 157
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:PRK10908 158 VLLADEPTGNLDDALSEGILRLFEEFN-RVGVTVLMATHDIGLISRRSYRMLTLSDGHL 215
|
|
| ABC_DrrA |
cd03265 |
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein ... |
2-223 |
2.10e-52 |
|
Daunorubicin/doxorubicin resistance ATP-binding protein; DrrA is the ATP-binding protein component of a bacterial exporter complex that confers resistance to the antibiotics daunorubicin and doxorubicin. In addition to DrrA, the complex includes an integral membrane protein called DrrB. DrrA belongs to the ABC family of transporters and shares sequence and functional similarities with a protein found in cancer cells called P-glycoprotein. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213232 [Multi-domain] Cd Length: 220 Bit Score: 172.55 E-value: 2.10e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValpeRELTLAR 81
Cdd:cd03265 1 IEVENLVKKYGD----FEAVRGVSFRVRRGEIFGLLGPNGAGKTTTIKMLTTLLKPTSGRATVAGHDVV----REPREVR 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03265 73 RRIGIVFQDLSVDDELTGWENLYIHARLYGVPGAERRERIDELLDFVGLLEAADRLVKTYSGGMRRRLEIARSLVHRPEV 152
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03265 153 LFLDEPTIGLDPQTRAHVWEYIEKLKEEFGMTILLTTHYMEEAEQLCDRVAIIDHGRIIAEG 214
|
|
| TauB |
COG4525 |
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism]; |
1-202 |
8.18e-52 |
|
ABC-type taurine transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443596 [Multi-domain] Cd Length: 262 Bit Score: 172.35 E-value: 8.18e-52
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPEreltlA 80
Cdd:COG4525 3 MLTVRHVSVRYPGGGQPQPALQDVSLTIESGEFVVALGASGCGKTTLLNLIAGFLAPSSGEITLDGVP-VTGPG-----A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRqiGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG4525 77 DR--GVVFQKDALLPWLNVLDNVAFGLRLRGVPKAERRARAEELLALVGLADFARRRIWQLSGGMRQRVGIARALAADPR 154
|
170 180 190 200
....*....|....*....|....*....|....*....|..
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD 202
Cdd:COG4525 155 FLLMDEPFGALDALTREQMQELLLDVWQRTGKGVFLITHSVE 196
|
|
| dppF |
PRK11308 |
dipeptide transporter ATP-binding subunit; Provisional |
6-231 |
1.61e-51 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 236898 [Multi-domain] Cd Length: 327 Bit Score: 173.61 E-value: 1.61e-51
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 6 GLNKVY------GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTL 79
Cdd:PRK11308 10 DLKKHYpvkrglFKPERLVKALDGVSFTLERGKTLAVVGESGCGKSTLARLLTMIETPTGGELYYQGQDLLKADPEAQKL 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQH-FNLLSSR-TVFANIAFPLEL-AGWSKSQIRARVDELLALVGLEAR-AHAYPSELSGGQKQRVAIARAL 155
Cdd:PRK11308 90 LRQKIQIVFQNpYGSLNPRkKVGQILEEPLLInTSLSAAERREKALAMMAKVGLRPEhYDRYPHMFSGGQRQRIAIARAL 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSN 231
Cdd:PRK11308 170 MLDPDVVVADEPVSALDVSVQAQVLNLMMDLQQELGLSYVFISHDLSVVEHIADEVMVMYLGRCVEKGTKEQIFNN 245
|
|
| cbiO |
PRK13637 |
energy-coupling factor transporter ATPase; |
2-251 |
1.27e-50 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237455 [Multi-domain] Cd Length: 287 Bit Score: 170.23 E-value: 1.27e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlPERELTLA 80
Cdd:PRK13637 3 IKIENLTHIYMEGTPfEKKALDNVNIEIEDGEFVGLIGHTGSGKSTLIQHLNGLLKPTSGKIIIDGVDITD-KKVKLSDI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNL-LSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGL--EARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:PRK13637 82 RKKVGLVFQYPEYqLFEETIEKDIAFGPINLGLSEEEIENRVKRAMNIVGLdyEDYKDKSPFELSGGQKRRVAIAGVVAM 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQla 237
Cdd:PRK13637 162 EPKILILDEPTAGLDPKGRDEILNKIKELHKEYNMTIILVSHSMEDVAKLADRIIVMNKGKCELQGTPREVFKEVETL-- 239
|
250
....*....|....
gi 754651031 238 rdfihSTIHLEVPQ 251
Cdd:PRK13637 240 -----ESIGLAVPQ 248
|
|
| ABC_ModC_molybdenum_transporter |
cd03297 |
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type ... |
23-223 |
1.29e-50 |
|
ATP-binding cassette domain of the molybdenum transport system; ModC is an ABC-type transporter and the ATPase component of a molybdate transport system that also includes the periplasmic binding protein ModA and the membrane protein ModB. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213264 [Multi-domain] Cd Length: 214 Bit Score: 167.86 E-value: 1.29e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIfGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDL------VALPEReltlaRRQIGMIFQHFNLLSS 96
Cdd:cd03297 16 KIDFDLNEEVT-GIFGASGAGKSTLLRCIAGLEKPDGGTIVLNGTVLfdsrkkINLPPQ-----QRKIGLVFQQYALFPH 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAFPLElaGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTT 176
Cdd:cd03297 90 LNVRENLAFGLK--RKRNREDRISVDELLDLLGLDHLLNRYPAQLSGGEKQRVALARALAAQPELLLLDEPFSALDRALR 167
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 754651031 177 RSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03297 168 LQLLPELKQIKKNLNIPVIFVTHDLSEAEYLADRIVVMEDGRLQYIG 214
|
|
| ABC_drug_resistance_like |
cd03264 |
ABC-type multidrug transport system, ATPase component; The biological function of this family ... |
2-223 |
1.46e-50 |
|
ABC-type multidrug transport system, ATPase component; The biological function of this family is not well characterized, but display ABC domains similar to members of ABCA subfamily. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213231 [Multi-domain] Cd Length: 211 Bit Score: 167.37 E-value: 1.46e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGkIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlAR 81
Cdd:cd03264 1 LQLENLTKRYGKK----RALDGVSLTLGPG-MYGLLGPNGAGKTTLMRILATLTPPSSGTIRIDGQDVLKQPQK----LR 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03264 72 RRIGYLPQEFGVYPNFTVREFLDYIAWLKGIPSKEVKARVDEVLELVNLGDRAKKKIGSLSGGMRRRVGIAQALVGDPSI 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03264 152 LIVDEPTAGLDPEERIRFRNLLSELGE--DRIVILSTHIVEDVESLCNQVAVLNKGKLVFEG 211
|
|
| lolD |
PRK11629 |
lipoprotein-releasing ABC transporter ATP-binding protein LolD; |
1-205 |
1.78e-50 |
|
lipoprotein-releasing ABC transporter ATP-binding protein LolD;
Pssm-ID: 183244 [Multi-domain] Cd Length: 233 Bit Score: 168.07 E-value: 1.78e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPER-ELTL 79
Cdd:PRK11629 5 LLQCDNLCKRYQEGSVQTDVLHNVSFSIGEGEMMAIVGSSGSGKSTLLHLLGGLDTPTSGDVIFNGQPMSKLSSAaKAEL 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK11629 85 RNQKLGFIYQFHHLLPDFTALENVAMPLLIGKKKPAEINSRALEMLAAVGLEHRANHRPSELSGGERQRVAIARALVNNP 164
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVK 205
Cdd:PRK11629 165 RLVLADEPTGNLDARNADSIFQLLGELNRLQGTAFLVVTHDLQLAK 210
|
|
| FetA |
COG4619 |
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism]; |
21-219 |
6.07e-50 |
|
ABC-type iron transporter FetAB, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443661 [Multi-domain] Cd Length: 209 Bit Score: 165.76 E-value: 6.07e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLSSrTVF 100
Cdd:COG4619 16 LSPVSLTLEAGECVAITGPSGSGKSTLLRALADLDPPTSGEIYLDGKPLSAMPPPEW---RRQVAYVPQEPALWGG-TVR 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPLELAGwsKSQIRARVDELLALVGLEARAHAYP-SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSI 179
Cdd:COG4619 92 DNLPFPFQLRE--RKFDRERALELLERLGLPPDILDKPvERLSGGERQRLALIRALLLQPDVLLLDEPTSALDPENTRRV 169
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 754651031 180 LSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:COG4619 170 EELLREYLAEEGRAVLWVSHDPEQIERVADRVLTLEAGRL 209
|
|
| PRK10851 |
PRK10851 |
sulfate/thiosulfate ABC transporter ATP-binding protein CysA; |
2-222 |
7.60e-50 |
|
sulfate/thiosulfate ABC transporter ATP-binding protein CysA;
Pssm-ID: 182778 [Multi-domain] Cd Length: 353 Bit Score: 170.26 E-value: 7.60e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlar 81
Cdd:PRK10851 3 IEIANIKKSFGR----TQVLNDISLDIPSGQMVALLGPSGSGKTTLLRIIAGLEHQTSGHIRFHGTDVSRLHARD----- 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGW----SKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:PRK10851 74 RKVGFVFQHYALFRHMTVFDNIAFGLTVLPRrerpNAAAIKAKVTQLLEMVQLAHLADRYPAQLSGGQKQRVALARALAV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSlIEQ 222
Cdd:PRK10851 154 EPQILLLDEPFGALDAQVRKELRRWLRQLHEELKFTSVFVTHDQEEAMEVADRVVVMSQGN-IEQ 217
|
|
| ABC_Metallic_Cations |
cd03235 |
ATP-binding cassette domain of the metal-type transporters; This family includes transporters ... |
16-214 |
9.79e-50 |
|
ATP-binding cassette domain of the metal-type transporters; This family includes transporters involved in the uptake of various metallic cations such as iron, manganese, and zinc. The ATPases of this group of transporters are very similar to members of iron-siderophore uptake family suggesting that they share a common ancestor. The best characterized metal-type ABC transporters are the YfeABCD system of Y. pestis, the SitABCD system of Salmonella enterica serovar Typhimurium, and the SitABCD transporter of Shigella flexneri. Moreover other uncharacterized homologs of these metal-type transporters are mainly found in pathogens like Haemophilus or enteroinvasive E. coli isolates.
Pssm-ID: 213202 [Multi-domain] Cd Length: 213 Bit Score: 165.40 E-value: 9.79e-50
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 16 DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalperelTLARRQIGMIFQHFNLLS 95
Cdd:cd03235 10 GGHPVLEDVSFEVKPGEFLAIVGPNGAGKSTLLKAILGLLKPTSGSIRVFGKPL--------EKERKRIGYVPQRRSIDR 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SR--TVFANIAFPL----ELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:cd03235 82 DFpiSVRDVVLMGLyghkGLFRRLSKADKAKVDEALERVGLSELADRQIGELSGGQQQRVLLARALVQDPDLLLLDEPFA 161
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 754651031 170 ALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAII 214
Cdd:cd03235 162 GVDPKTQEDIYELLRELR-REGMTILVVTHDLGLVLEYFDRVLLL 205
|
|
| cbiO |
PRK13635 |
energy-coupling factor ABC transporter ATP-binding protein; |
20-268 |
1.60e-49 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184195 [Multi-domain] Cd Length: 279 Bit Score: 167.11 E-value: 1.60e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERELTLARRQIGMIFQH-FNLLSSRT 98
Cdd:PRK13635 22 ALKDVSFSVYEGEWVAIVGHNGSGKSTLAKLLNGLLLPEAGTITVGGM---VLSEETVWDVRRQVGMVFQNpDNQFVGAT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:PRK13635 99 VQDDVAFGLENIGVPREEMVERVDQALRQVGMEDFLNREPHRLSGGQKQRVAIAGVLALQPDIIILDEATSMLDPRGRRE 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 179 ILSLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSNAkTQLARdfihstIHLEVPqeYQDRLS 258
Cdd:PRK13635 179 VLETVRQLKEQKGITVLSITHDLDEAAQ-ADRVIVMNKGEILEEGTPEEIFKSG-HMLQE------IGLDVP--FSVKLK 248
|
250
....*....|
gi 754651031 259 AERVANSYPL 268
Cdd:PRK13635 249 ELLKRNGILL 258
|
|
| ABC_tran |
pfam00005 |
ABC transporter; ABC transporters for a large family of proteins responsible for translocation ... |
21-169 |
1.87e-49 |
|
ABC transporter; ABC transporters for a large family of proteins responsible for translocation of a variety of compounds across biological membranes. ABC transporters are the largest family of proteins in many completely sequenced bacteria. ABC transporters are composed of two copies of this domain and two copies of a transmembrane domain pfam00664. These four domains may belong to a single polypeptide or belong in different polypeptide chains.
Pssm-ID: 394964 [Multi-domain] Cd Length: 150 Bit Score: 162.43 E-value: 1.87e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlvaLPERELTLARRQIGMIFQHFNLLSSRTVF 100
Cdd:pfam00005 1 LKNVSLTLNPGEILALVGPNGAGKSTLLKLIAGLLSPTEGTILLDGQD---LTDDERKSLRKEIGYVFQDPQLFPRLTVR 77
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 101 ANIAFPLELAGWSKSQIRARVDELLALVGLEA----RAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:pfam00005 78 ENLRLGLLLKGLSKREKDARAEEALEKLGLGDladrPVGERPGTLSGGQRQRVAIARALLTKPKLLLLDEPTA 150
|
|
| PRK13633 |
PRK13633 |
energy-coupling factor transporter ATPase; |
1-251 |
4.26e-49 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237453 [Multi-domain] Cd Length: 280 Bit Score: 166.03 E-value: 4.26e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVH--ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlvALPERELT 78
Cdd:PRK13633 4 MIKCKNVSYKYESNEESTEklALDDVNLEVKKGEFLVILGRNGSGKSTIAKHMNALLIPSEGKVYVDGLD--TSDEENLW 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 LARRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGL-EARAHAyPSELSGGQKQRVAIARALA 156
Cdd:PRK13633 82 DIRNKAGMVFQNpDNQIVATIVEEDVAFGPENLGIPPEEIRERVDESLKKVGMyEYRRHA-PHLLSGGQKQRVAIAGILA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD-VVKGicDDVAIISDGSLIEQGEVAWFFSNAKTQ 235
Cdd:PRK13633 161 MRPECIIFDEPTAMLDPSGRREVVNTIKELNKKYGITIILITHYMEeAVEA--DRIIVMDSGKVVMEGTPKEIFKEVEMM 238
|
250
....*....|....*.
gi 754651031 236 lardfihSTIHLEVPQ 251
Cdd:PRK13633 239 -------KKIGLDVPQ 247
|
|
| ABC_TM1139_LivF_branched |
cd03224 |
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of ... |
2-226 |
4.80e-49 |
|
ATP-binding cassette domain of branched-chain amino acid transporter; LivF (TM1139) is part of the LIV-I bacterial ABC-type two-component transport system that imports neutral, branched-chain amino acids. The E. coli branched-chain amino acid transporter comprises a heterodimer of ABC transporters (LivF and LivG), a heterodimer of six-helix TM domains (LivM and LivH), and one of two alternative soluble periplasmic substrate binding proteins (LivK or LivJ). ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules.
Pssm-ID: 213191 [Multi-domain] Cd Length: 222 Bit Score: 163.76 E-value: 4.80e-49
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltLAR 81
Cdd:cd03224 1 LEVENLNAGYGK----SQILFGVSLTVPEGEIVALLGRNGAGKTTLLKTIMGLLPPRSGSIRFDGRDITGLPPHE--RAR 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANiafpLELAGW--SKSQIRARVDELLALV-GLEARAHAYPSELSGGQKQRVAIARALAPA 158
Cdd:cd03224 75 AGIGYVPEGRRIFPELTVEEN----LLLGAYarRRAKRKARLERVYELFpRLKERRKQLAGTLSGGEQQMLAIARALMSR 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 159 PKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:cd03224 151 PKLLLLDEPSEGLAPKIVEEIFEAIRELR-DEGVTILLVEQNARFALEIADRAYVLERGRVVLEGTAA 217
|
|
| YhaQ |
COG4152 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-292 |
2.25e-48 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443322 [Multi-domain] Cd Length: 298 Bit Score: 164.51 E-value: 2.25e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPereltla 80
Cdd:COG4152 1 MLELKGLTKRFGD----KTAVDDVSFTVPKGEIFGLLGPNGAGKTTTIRIILGILAPDSGEVLWDGEPLDPED------- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIG-----------MifqhfnllssrTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRV 149
Cdd:COG4152 70 RRRIGylpeerglypkM-----------KVGEQLVYLARLKGLSKAEAKRRADEWLERLGLGDRANKKVEELSKGNQQKV 138
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAwff 229
Cdd:COG4152 139 QLIAALLHDPELLILDEPFSGLDPVNVELLKDVIRELAAK-GTTVIFSSHQMELVEELCDRIVIINKGRKVLSGSVD--- 214
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 230 sNAKTQLARDFIHstIHLEVPQEYQDRLSAERVANSYPL-VKLGFTGSTVDTPLISEASRRFNI 292
Cdd:COG4152 215 -EIRRQFGRNTLR--LEADGDAGWLRALPGVTVVEEDGDgAELKLEDGADAQELLRALLARGPV 275
|
|
| PRK10070 |
PRK10070 |
proline/glycine betaine ABC transporter ATP-binding protein ProV; |
20-290 |
2.43e-48 |
|
proline/glycine betaine ABC transporter ATP-binding protein ProV;
Pssm-ID: 182221 [Multi-domain] Cd Length: 400 Bit Score: 167.52 E-value: 2.43e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQ-IGMIFQHFNLLSSRT 98
Cdd:PRK10070 43 GVKDASLAIEEGEIFVIMGLSGSGKSTMVRLLNRLIEPTRGQVLIDGVDIAKISDAELREVRRKkIAMVFQSFALMPHMT 122
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:PRK10070 123 VLDNTAFGMELAGINAEERREKALDALRQVGLENYAHSYPDELSGGMRQRVGLARALAINPDILLMDEAFSALDPLIRTE 202
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 179 ILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHStihLEVPQEYQDRLS 258
Cdd:PRK10070 203 MQDELVKLQAKHQRTIVFISHDLDEAMRIGDRIAIMQNGEVVQVGTPDEILNNPANDYVRTFFRG---VDISQVFSAKDI 279
|
250 260 270
....*....|....*....|....*....|..
gi 754651031 259 AERVANSYPLVKLGFtGSTVDTPLISEASRRF 290
Cdd:PRK10070 280 ARRTPNGLIRKTPGF-GPRSALKLLQDEDREY 310
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
1-226 |
3.32e-48 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 169.04 E-value: 3.32e-48
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlA 80
Cdd:COG1129 4 LLEMRGISKSFG----GVKALDGVSLELRPGEVHALLGENGAGKSTLMKILSGVYQPDSGEILLDGEPVRFRSPRD---A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQ-IGMIFQHFNLLSSRTVFANIAFPLELAGW---SKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:COG1129 77 QAAgIAIIHQELNLVPNLSVAENIFLGREPRRGgliDWRAMRRRARELLARLGLDIDPDTPVGDLSVAQQQLVEIARALS 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG1129 157 RDARVLILDEPTASLTEREVERLFRIIRRL-KAQGVAIIYISHRLDEVFEIADRVTVLRDGRLVGTGPVA 225
|
|
| cbiO |
PRK13650 |
energy-coupling factor transporter ATPase; |
1-217 |
1.75e-47 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184209 [Multi-domain] Cd Length: 279 Bit Score: 161.82 E-value: 1.75e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAvHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERELTLA 80
Cdd:PRK13650 4 IIEVKNLTFKYKEDQEK-YTLNDVSFHVKQGEWLSIIGHNGSGKSTTVRLIDGLLEAESGQIIIDGD---LLTEENVWDI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK13650 80 RHKIGMVFQNpDNQFVGATVEDDVAFGLENKGIPHEEMKERVNEALELVGMQDFKEREPARLSGGQKQRVAIAGAVAMRP 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVkGICDDVAIISDG 217
Cdd:PRK13650 160 KIIILDEATSMLDPEGRLELIKTIKGIRDDYQMTVISITHDLDEV-ALSDRVLVMKNG 216
|
|
| potA |
PRK09452 |
spermidine/putrescine ABC transporter ATP-binding protein PotA; |
2-222 |
3.53e-47 |
|
spermidine/putrescine ABC transporter ATP-binding protein PotA;
Pssm-ID: 236523 [Multi-domain] Cd Length: 375 Bit Score: 163.58 E-value: 3.53e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYgkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlaR 81
Cdd:PRK09452 15 VELRGISKSF----DGKEVISNLDLTINNGEFLTLLGPSGCGKTTVLRLIAGFETPDSGRIMLDGQDITHVPAE-----N 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:PRK09452 86 RHVNTVFQSYALFPHMTVFENVAFGLRMQKTPAAEITPRVMEALRMVQLEEFAQRKPHQLSGGQQQRVAIARAVVNKPKV 165
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGsLIEQ 222
Cdd:PRK09452 166 LLLDESLSALDYKLRKQMQNELKALQRKLGITFVFVTHDQEEALTMSDRIVVMRDG-RIEQ 225
|
|
| ModC |
COG4148 |
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and ... |
23-226 |
4.05e-47 |
|
ABC-type molybdate transport system, ATPase component ModC [Inorganic ion transport and metabolism]; ABC-type molybdate transport system, ATPase component ModC is part of the Pathway/BioSystem: Molybdopterin biosynthesis
Pssm-ID: 443319 [Multi-domain] Cd Length: 358 Bit Score: 162.96 E-value: 4.05e-47
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlPERELTLA--RRQIGMIFQHFNLLSSRTVF 100
Cdd:COG4148 17 DVDFTLPGRGVTALFGPSGSGKTTLLRAIAGLERPDSGRIRLGGEVLQD-SARGIFLPphRRRIGYVFQEARLFPHLSVR 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPLELAGwsKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSIL 180
Cdd:COG4148 96 GNLLYGRKRAP--RAERRISFDEVVELLGIGHLLDRRPATLSGGERQRVAIGRALLSSPRLLLMDEPLAALDLARKAEIL 173
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 754651031 181 SLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG4148 174 PYLERLRDELDIPILYVSHSLDEVARLADHVVLLEQGRVVASGPLA 219
|
|
| cbiO |
PRK13639 |
cobalt transporter ATP-binding subunit; Provisional |
16-234 |
1.44e-46 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184199 [Multi-domain] Cd Length: 275 Bit Score: 159.09 E-value: 1.44e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 16 DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvALPERELTLARRQIGMIFQHF-NLL 94
Cdd:PRK13639 13 DGTEALKGINFKAEKGEMVALLGPNGAGKSTLFLHFNGILKPTSGEVLIKGEPI-KYDKKSLLEVRKTVGIVFQNPdDQL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANIAF-PLELaGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:PRK13639 92 FAPTVEEDVAFgPLNL-GLSKEEVEKRVKEALKAVGMEGFENKPPHHLSGGQKKRVAIAGILAMKPEIIVLDEPTSGLDP 170
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 174 QTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:PRK13639 171 MGASQIMKLLYDLN-KEGITIIISTHDVDLVPVYADKVYVMSDGKIIKEGTPKEVFSDIET 230
|
|
| ABC_ATPase |
cd00267 |
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large ... |
3-217 |
2.20e-46 |
|
ATP-binding cassette transporter nucleotide-binding domain; ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213179 [Multi-domain] Cd Length: 157 Bit Score: 154.71 E-value: 2.20e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 3 KLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRR 82
Cdd:cd00267 1 EIENLSFRYGGR----TALDNVSLTLKAGEIVALVGPNGSGKSTLLRAIAGLLKPTSGEILIDGKDIAKLPLEEL---RR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIGMIFQhfnllssrtvfaniafplelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPAPKVL 162
Cdd:cd00267 74 RIGYVPQ---------------------------------------------------LSGGQRQRVALARALLLNPDLL 102
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 163 LCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd00267 103 LLDEPTSGLDPASRERLLELLRELAEE-GRTVIIVTHDPELAELAADRVIVLKDG 156
|
|
| cbiO |
PRK13632 |
cobalt transporter ATP-binding subunit; Provisional |
1-233 |
4.25e-46 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237452 [Multi-domain] Cd Length: 271 Bit Score: 157.85 E-value: 4.25e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGqdlVALPERELTLA 80
Cdd:PRK13632 7 MIKVENVSFSYPNSEN--NALKNVSFEINEGEYVAILGHNGSGKSTISKILTGLLKPQSGEIKIDG---ITISKENLKEI 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK13632 82 RKKIGIIFQNpDNQFIGATVEDDIAFGLENKKVPPKKMKDIIDDLAKKVGMEDYLDKEPQNLSGGQKQRVAIASVLALNP 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMD-VVKgiCDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:PRK13632 162 EIIIFDESTSMLDPKGKREIKKIMVDLRKTRKKTLISITHDMDeAIL--ADKVIVFSEGKLIAQGKPKEILNNKE 234
|
|
| ABC_NatA_sodium_exporter |
cd03266 |
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a ... |
1-223 |
6.87e-46 |
|
ATP-binding cassette domain of the Na+ transporter; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of a single ATP-binding protein and a single integral membrane protein.
Pssm-ID: 213233 [Multi-domain] Cd Length: 218 Bit Score: 155.60 E-value: 6.87e-46
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPeREltlA 80
Cdd:cd03266 1 MITADALTKRFRDVKKTVQAVDGVSFTVKPGEVTGLLGPNGAGKTTTLRMLAGLLEPDAGFATVDGFDVVKEP-AE---A 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:cd03266 77 RRRLGFVSDSTGLYDRLTARENLEYFAGLYGLKGDELTARLEELADRLGMEELLDRRVGGFSTGMRQKVAIARALVHDPP 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03266 157 VLLLDEPTTGLDVMATRALREFIRQLR-ALGKCILFSTHIMQEVERLCDRVVVLHRGRVVYEG 218
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
1-226 |
1.12e-45 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 162.50 E-value: 1.12e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvalperELTL- 79
Cdd:COG3845 5 ALELRGITKRFG----GVVANDDVSLTVRPGEIHALLGENGAGKSTLMKILYGLYQPDSGEILIDGK--------PVRIr 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ----ARRQ-IGMIFQHFNLLSSRTVFANIAF---PLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAI 151
Cdd:COG3845 73 sprdAIALgIGMVHQHFMLVPNLTVAENIVLglePTKGGRLDRKAARARIRELSERYGLDVDPDAKVEDLSVGEQQRVEI 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 152 ARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG3845 153 LKALYRGARILILDEPTAVLTPQEADELFEILRRL-AAEGKSIIFITHKLREVMAIADRVTVLRRGKVVGTVDTA 226
|
|
| fbpC |
PRK11432 |
ferric ABC transporter ATP-binding protein; |
4-223 |
1.42e-45 |
|
ferric ABC transporter ATP-binding protein;
Pssm-ID: 183133 [Multi-domain] Cd Length: 351 Bit Score: 158.73 E-value: 1.42e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValperELTLARRQ 83
Cdd:PRK11432 9 LKNITKRFGSNT----VIDNLNLTIKQGTMVTLLGPSGCGKTTVLRLVAGLEKPTEGQIFIDGEDVT-----HRSIQQRD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 84 IGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLL 163
Cdd:PRK11432 80 ICMVFQSYALFPHMSLGENVGYGLKMLGVPKEERKQRVKEALELVDLAGFEDRYVDQISGGQQQRVALARALILKPKVLL 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 164 CDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11432 160 FDEPLSNLDANLRRSMREKIRELQQQFNITSLYVTHDQSEAFAVSDTVIVMNKGKIMQIG 219
|
|
| ABC_Iron-Siderophores_B12_Hemin |
cd03214 |
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related ... |
3-223 |
1.64e-45 |
|
ATP-binding component of iron-siderophores, vitamin B12 and hemin transporters and related proteins; ABC transporters, involved in the uptake of siderophores, heme, and vitamin B12, are widely conserved in bacteria and archaea. Only very few species lack representatives of the siderophore family transporters. The E. coli BtuCD protein is an ABC transporter mediating vitamin B12 uptake. The two ATP-binding cassettes (BtuD) are in close contact with each other, as are the two membrane-spanning subunits (BtuC); this arrangement is distinct from that observed for the E. coli lipid flippase MsbA. The BtuC subunits provide 20 transmembrane helices grouped around a translocation pathway that is closed to the cytoplasm by a gate region, whereas the dimer arrangement of the BtuD subunits resembles the ATP-bound form of the Rad50 DNA repair enzyme. A prominent cytoplasmic loop of BtuC forms the contact region with the ATP-binding cassette and represent a conserved motif among the ABC transporters.
Pssm-ID: 213181 [Multi-domain] Cd Length: 180 Bit Score: 153.36 E-value: 1.64e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 3 KLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRR 82
Cdd:cd03214 1 EVENLSVGYGGR----TVLDDLSLSIEAGEIVGILGPNGAGKSTLLKTLAGLLKPSSGEILLDGKDLASLSPKEL---AR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIGMIFQhfnllssrtvfaniafplelagwsksqirarvdeLLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVL 162
Cdd:cd03214 74 KIAYVPQ----------------------------------ALELLGLAHLADRPFNELSGGERQRVLLARALAQEPPIL 119
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 163 LCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03214 120 LLDEPTSHLDIAHQIELLELLRRLARERGKTVVMVLHDLNLAARYADRVILLKDGRIVAQG 180
|
|
| ABC_BcrA_bacitracin_resist |
cd03268 |
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily ... |
2-223 |
2.52e-45 |
|
ATP-binding cassette domain of the bacitracin-resistance transporter; The BcrA subfamily represents ABC transporters involved in peptide antibiotic resistance. Bacitracin is a dodecapeptide antibiotic produced by B. licheniformis and B. subtilis. The synthesis of bacitracin is non-ribosomally catalyzed by a multi-enzyme complex BcrABC. Bacitracin has potent antibiotic activity against gram-positive bacteria. The inhibition of peptidoglycan biosynthesis is the best characterized bacterial effect of bacitracin. The bacitracin resistance of B. licheniformis is mediated by the ABC transporter Bcr which is composed of two identical BcrA ATP-binding subunits and one each of the integral membrane proteins, BcrB and BcrC. B. subtilis cells carrying bcr genes on high-copy number plasmids develop collateral detergent sensitivity, a similar phenomenon in human cells with overexpressed multi-drug resistance P-glycoprotein.
Pssm-ID: 213235 [Multi-domain] Cd Length: 208 Bit Score: 153.91 E-value: 2.52e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlAR 81
Cdd:cd03268 1 LKTNDLTKTYGKK----RVLDDISLHVKKGEIYGFLGPNGAGKTTTMKIILGLIKPDSGEITFDGKSYQKNIE-----AL 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSqiraRVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03268 72 RRIGALIEAPGFYPNLTARENLRLLARLLGIRKK----RIDEVLDVVGLKDSAKKKVKGFSLGMKQRLGIALALLGNPDL 147
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03268 148 LILDEPTNGLDPDGIKELRELILSLR-DQGITVLISSHLLSEIQKVADRIGIINKGKLIEEG 208
|
|
| SunT |
COG2274 |
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase ... |
2-223 |
5.74e-45 |
|
ABC-type bacteriocin/lantibiotic exporters, contain an N-terminal double-glycine peptidase domain [Defense mechanisms];
Pssm-ID: 441875 [Multi-domain] Cd Length: 711 Bit Score: 163.47 E-value: 5.74e-45
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:COG2274 474 IELENVSFRYPGDSPPV--LDNISLTIKPGERVAIVGRSGSGKSTLLKLLLGLYEPTSGRILIDGIDLRQIDPASL---R 548
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHfNLLSSRTVFANIAFplelagWSKSQIRARVDELLALVGLEARAHAYP-----------SELSGGQKQRVA 150
Cdd:COG2274 549 RQIGVVLQD-VFLFSGTIRENITL------GDPDATDEEIIEAARLAGLHDFIEALPmgydtvvgeggSNLSGGQRQRLA 621
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 151 IARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKgICDDVAIISDGSLIEQG 223
Cdd:COG2274 622 IARALLRNPRILILDEATSALDAETEAIILENLRRL--LKGRTVIIIAHRLSTIR-LADRIIVLDKGRIVEDG 691
|
|
| nikE |
PRK10419 |
nickel ABC transporter ATP-binding protein NikE; |
21-226 |
1.09e-44 |
|
nickel ABC transporter ATP-binding protein NikE;
Pssm-ID: 236689 [Multi-domain] Cd Length: 268 Bit Score: 154.07 E-value: 1.09e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQH----FNllSS 96
Cdd:PRK10419 28 LNNVSLSLKSGETVALLGRSGCGKSTLARLLVGLESPSQGNVSWRGEPLAKLNRAQRKAFRRDIQMVFQDsisaVN--PR 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAFPLE-LAGWSKSQIRARVDELLALVGLEAR-AHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQ 174
Cdd:PRK10419 106 KTVREIIREPLRhLLSLDKAERLARASEMLRAVDLDDSvLDKRPPQLSGGQLQRVCLARALAVEPKLLILDEAVSNLDLV 185
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 175 TTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:PRK10419 186 LQAGVIRLLKKLQQQFGTACLFITHDLRLVERFCQRVMVMDNGQIVETQPVG 237
|
|
| ABCC_MRP_Like |
cd03228 |
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP ... |
2-217 |
1.30e-44 |
|
ATP-binding cassette domain of multidrug resistance protein-like transporters; The MRP (Multidrug Resistance Protein)-like transporters are involved in drug, peptide, and lipid export. They belong to the subfamily C of the ATP-binding cassette (ABC) superfamily of transport proteins. The ABCC subfamily contains transporters with a diverse functional spectrum that includes ion transport, cell surface receptor, and toxin secretion activities. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains, each composed of six transmembrane (TM) helices, and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213195 [Multi-domain] Cd Length: 171 Bit Score: 150.61 E-value: 1.30e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLER---PTEGQVIVDGQDLVALPERELt 78
Cdd:cd03228 1 IEFKNVSFSYP--GRPKPVLKDVSLTIKPGEKVAIVGPSGSGKSTLL---KLLLRlydPTSGEILIDGVDLRDLDLESL- 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 laRRQIGMIFQHFNLLSsRTVFANIafplelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPA 158
Cdd:cd03228 75 --RKNIAYVPQDPFLFS-GTIRENI-------------------------------------LSGGQRQRIAIARALLRD 114
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 159 PKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKgICDDVAIISDG 217
Cdd:cd03228 115 PPILILDEATSALDPETEALILEALRAL--AKGKTVIVIAHRLSTIR-DADRIIVLDDG 170
|
|
| cbiO |
PRK13636 |
cobalt transporter ATP-binding subunit; Provisional |
1-238 |
2.26e-44 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184196 [Multi-domain] Cd Length: 283 Bit Score: 153.85 E-value: 2.26e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYgkgSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPERELTLA 80
Cdd:PRK13636 5 ILKVEELNYNY---SDGTHALKGININIKKGEVTAILGGNGAGKSTLFQNLNGILKPSSGRILFDGKP-IDYSRKGLMKL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK13636 81 RESVGMVFQDpDNQLFSASVYQDVSFGAVNLKLPEDEVRKRVDNALKRTGIEHLKDKPTHCLSFGQKKRVAIAGVLVMEP 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFsnAKTQLAR 238
Cdd:PRK13636 161 KVLVLDEPTAGLDPMGVSEIMKLLVEMQKELGLTIIIATHDIDIVPLYCDNVFVMKEGRVILQGNPKEVF--AEKEMLR 237
|
|
| MdlB |
COG1132 |
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms]; |
20-223 |
3.18e-44 |
|
ABC-type multidrug transport system, ATPase and permease component [Defense mechanisms];
Pssm-ID: 440747 [Multi-domain] Cd Length: 579 Bit Score: 159.95 E-value: 3.18e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQHFNLL 94
Cdd:COG1132 355 VLKDISLTIPPGETVALVGPSGSGKSTL---VNLLLRfydPTSGRILIDGVDI-----RDLTLEslRRQIGVVPQDTFLF 426
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SsRTVFANIAFPLELAGwsksqiRARVDELLALVGLEARAHAYP-----------SELSGGQKQRVAIARALAPAPKVLL 163
Cdd:COG1132 427 S-GTIRENIRYGRPDAT------DEEVEEAAKAAQAHEFIEALPdgydtvvgergVNLSGGQRQRIAIARALLKDPPILI 499
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 164 CDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:COG1132 500 LDEATSALDTETEALIQEALERLMK--GRTTIVIAHRLSTIRN-ADRILVLDDGRIVEQG 556
|
|
| PRK15079 |
PRK15079 |
oligopeptide ABC transporter ATP-binding protein OppF; Provisional |
20-233 |
4.11e-44 |
|
oligopeptide ABC transporter ATP-binding protein OppF; Provisional
Pssm-ID: 185037 [Multi-domain] Cd Length: 331 Bit Score: 154.48 E-value: 4.11e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQhfNLLSS--- 96
Cdd:PRK15079 36 AVDGVTLRLYEGETLGVVGESGCGKSTFARAIIGLVKATDGEVAWLGKDLLGMKDDEWRAVRSDIQMIFQ--DPLASlnp 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 -RTVFANIAFPLEL--AGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK15079 114 rMTIGEIIAEPLRTyhPKLSRQEVKDRVKAMMLKVGLlPNLINRYPHEFSGGQCQRIGIARALILEPKLIICDEPVSALD 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 173 PQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:PRK15079 194 VSIQAQVVNLLQQLQREMGLSLIFIAHDLAVVKHISDRVLVMYLGHAVELGTYDEVYHNPL 254
|
|
| LivF |
COG0410 |
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid ... |
1-226 |
4.41e-44 |
|
ABC-type branched-chain amino acid transport system, ATPase component LivF [Amino acid transport and metabolism];
Pssm-ID: 440179 [Multi-domain] Cd Length: 236 Bit Score: 151.67 E-value: 4.41e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltLA 80
Cdd:COG0410 3 MLEVENLHAGYGG----IHVLHGVSLEVEEGEIVALLGRNGAGKTTLLKAISGLLPPRSGSIRFDGEDITGLPPHR--IA 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANiafpLELAGW---SKSQIRARVDELLAL--VgLEARAHAYPSELSGGQKQRVAIARAL 155
Cdd:COG0410 77 RLGIGYVPEGRRIFPSLTVEEN----LLLGAYarrDRAEVRADLERVYELfpR-LKERRRQRAGTLSGGEQQMLAIGRAL 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG0410 152 MSRPKLLLLDEPSLGLAPLIVEEIFEIIRRLN-REGVTILLVEQNARFALEIADRAYVLERGRIVLEGTAA 221
|
|
| ntrCD |
TIGR01184 |
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits ... |
21-225 |
8.33e-44 |
|
nitrate transport ATP-binding subunits C and D; This model describes the ATP binding subunits of nitrate transport in bacteria and archaea. This protein belongs to the ATP-binding cassette (ABC) superfamily. It is thought that the two subunits encoded by ntrC and ntrD form the binding surface for interaction with ATP. This model is restricted in identifying ATP binding subunit associated with the nitrate transport. Nitrate assimilation is aided by other proteins derived from the operon which among others include products of ntrA - a regulatory protein; ntrB - a hydropbobic transmembrane permease and narB - a reductase. [Transport and binding proteins, Anions, Transport and binding proteins, Other]
Pssm-ID: 130252 [Multi-domain] Cd Length: 230 Bit Score: 150.69 E-value: 8.33e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAL-PERELtlarrqigmIFQHFNLLSSRTV 99
Cdd:TIGR01184 1 LKGVNLTIQQGEFISLIGHSGCGKSTLLNLISGLAQPTSGGVILEGKQITEPgPDRMV---------VFQNYSLLPWLTV 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLE--LAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTR 177
Cdd:TIGR01184 72 RENIALAVDrvLPDLSKSERRAIVEEHIALVGLTEAADKRPGQLSGGMKQRVAIARALSIRPKVLLLDEPFGALDALTRG 151
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 754651031 178 SILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:TIGR01184 152 NLQEELMQIWEEHRVTVLMVTHDVDEALLLSDRVVMLTNGPAANIGQI 199
|
|
| PRK10535 |
PRK10535 |
macrolide ABC transporter ATP-binding protein/permease MacB; |
1-220 |
8.71e-44 |
|
macrolide ABC transporter ATP-binding protein/permease MacB;
Pssm-ID: 182528 [Multi-domain] Cd Length: 648 Bit Score: 159.50 E-value: 8.71e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:PRK10535 4 LLELKDIRRSYPSGEEQVEVLKGISLDIYAGEMVAIVGASGSGKSTLMNILGCLDKPTSGTYRVAGQDVATLDADALAQL 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQ-IGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK10535 84 RREhFGFIFQRYHLLSHLTAAQNVEVPAVYAGLERKQRLLRAQELLQRLGLEDRVEYQPSQLSGGQQQRVSIARALMNGG 163
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGiCDDVAIISDGSLI 220
Cdd:PRK10535 164 QVILADEPTGALDSHSGEEVMAILHQLRDR-GHTVIIVTHDPQVAAQ-AERVIEIRDGEIV 222
|
|
| SapF |
COG4167 |
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms]; |
2-243 |
9.39e-44 |
|
ABC-type antimicrobial peptide export system, ATPase component SapF [Defense mechanisms];
Pssm-ID: 443328 [Multi-domain] Cd Length: 265 Bit Score: 151.53 E-value: 9.39e-44
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNK--VYGKG---SDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERE 76
Cdd:COG4167 5 LEVRNLSKtfKYRTGlfrRQQFEAVKPVSFTLEAGQTLAIIGENGSGKSTLAKMLAGIIEPTSGEILINGH---KLEYGD 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQHFNL-LSSRTvfaNIA----FPLELA-GWSKSQIRARVDELLALVGLEA-RAHAYPSELSGGQKQRV 149
Cdd:COG4167 82 YKYRCKHIRMIFQDPNTsLNPRL---NIGqileEPLRLNtDLTAEEREERIFATLRLVGLLPeHANFYPHMLSSGQKQRV 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPqTTRS-ILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWF 228
Cdd:COG4167 159 ALARALILQPKIIIADEALAALDM-SVRSqIINLMLELQEKLGISYIYVSQHLGIVKHISDKVLVMHQGEVVEYGKTAEV 237
|
250
....*....|....*
gi 754651031 229 FSNAKTQLARDFIHS 243
Cdd:COG4167 238 FANPQHEVTKRLIES 252
|
|
| PRK14267 |
PRK14267 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-241 |
7.70e-43 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184596 [Multi-domain] Cd Length: 253 Bit Score: 148.84 E-value: 7.70e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL-----ERPTEGQVIVDGQDLVAlPERE 76
Cdd:PRK14267 5 IETVNLRVYYGSN----HVIKGVDLKIPQNGVFALMGPSGCGKSTLLRTFNRLlelneEARVEGEVRLFGRNIYS-PDVD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQ--IRARVDELLALVGL----EARAHAYPSELSGGQKQRVA 150
Cdd:PRK14267 80 PIEVRREVGMVFQYPNPFPHLTIYDNVAIGVKLNGLVKSKkeLDERVEWALKKAALwdevKDRLNDYPSNLSGGQRQRLV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 151 IARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFS 230
Cdd:PRK14267 160 IARALAMKPKILLMDEPTANIDPVGTAKIEELLFEL--KKEYTIVLVTHSPAQAARVSDYVAFLYLGKLIEVGPTRKVFE 237
|
250
....*....|.
gi 754651031 231 NAKTQLARDFI 241
Cdd:PRK14267 238 NPEHELTEKYV 248
|
|
| ABC_ThiQ_thiamine_transporter |
cd03298 |
ATP-binding cassette domain of the thiamine transport system; Part of the ... |
2-223 |
1.39e-42 |
|
ATP-binding cassette domain of the thiamine transport system; Part of the binding-protein-dependent transport system tbpA-thiPQ for thiamine and TPP. Probably responsible for the translocation of thiamine across the membrane. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213265 [Multi-domain] Cd Length: 211 Bit Score: 146.87 E-value: 1.39e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlAR 81
Cdd:cd03298 1 VRLDKIRFSYG------EQPMHFDLTFAQGEITAIVGPSGSGKSTLLNLIAGFETPQSGRVLINGVDVTAAPP-----AD 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03298 70 RPVSMLFQENNLFAHLTVEQNVGLGLSPGLKLTAEDRQAIEVALARVGLAGLEKRLPGELSGGERQRVALARVLVRDKPV 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03298 150 LLLDEPFAALDPALRAEMLDLVLDLHAETKMTVLMVTHQPEDAKRLAQRVVFLDNGRIAAQG 211
|
|
| PhnL |
COG4778 |
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion ... |
1-218 |
2.44e-42 |
|
Alpha-D-ribose 1-methylphosphonate 5-triphosphate synthase subunit PhnL [Inorganic ion transport and metabolism];
Pssm-ID: 443809 [Multi-domain] Cd Length: 229 Bit Score: 146.81 E-value: 2.44e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNK---VYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ----DLVALP 73
Cdd:COG4778 4 LLEVENLSKtftLHLQGGKRLPVLDGVSFSVAAGECVALTGPSGAGKSTLLKCIYGNYLPDSGSILVRHDggwvDLAQAS 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 74 ERE-LTLARRQIGMIFQHFNLL---SSRTVFANiafPLELAGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQR 148
Cdd:COG4778 84 PREiLALRRRTIGYVSQFLRVIprvSALDVVAE---PLLERGVDREEARARARELLARLNLpERLWDLPPATFSGGEQQR 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 149 VAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGS 218
Cdd:COG4778 161 VNIARGFIADPPLLLLDEPTASLDAANRAVVVELIEEAKAR-GTAIIGIFHDEEVREAVADRVVDVTPFS 229
|
|
| PRK14247 |
PRK14247 |
phosphate ABC transporter ATP-binding protein; Provisional |
18-246 |
2.80e-42 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172735 [Multi-domain] Cd Length: 250 Bit Score: 147.37 E-value: 2.80e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL-----ERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFN 92
Cdd:PRK14247 16 VEVLDGVNLEIPDNTITALMGPSGSGKSTLLRVFNRLielypEARVSGEVYLDGQDIFKMDVIEL---RRRVQMVFQIPN 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 LLSSRTVFANIAFPLELAGW--SKSQIRARVDELLALVGL----EARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDE 166
Cdd:PRK14247 93 PIPNLSIFENVALGLKLNRLvkSKKELQERVRWALEKAQLwdevKDRLDAPAGKLSGGQQQRLCIARALAFQPEVLLADE 172
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 167 ATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHSTIH 246
Cdd:PRK14247 173 PTANLDPENTAKIESLFLEL--KKDMTIVLVTHFPQQAARISDYVAFLYKGQIVEWGPTREVFTNPRHELTEKYVTGRLY 250
|
|
| ABC_putative_ATPase |
cd03269 |
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the ... |
2-223 |
3.34e-42 |
|
ATP-binding cassette domain of an uncharacterized transporter; This subgroup is related to the subfamily A transporters involved in drug resistance, nodulation, lipid transport, and bacteriocin and lantibiotic immunity. In eubacteria and archaea, the typical organization consists of one ABC and one or two integral membranes. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region in addition to the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213236 [Multi-domain] Cd Length: 210 Bit Score: 145.89 E-value: 3.34e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlpereltLAR 81
Cdd:cd03269 1 LEVENVTKRFG----RVTALDDISFSVEKGEIFGLLGPNGAGKTTTIRMILGIILPDSGEVLFDGKPLDI-------AAR 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03269 70 NRIGYLPEERGLYPKMKVIDQLVYLAQLKGLKKEEARRRIDEWLERLELSEYANKRVEELSKGNQQKVQFIAAVIHDPEL 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03269 150 LILDEPFSGLDPVNVELLKDVIRELARA-GKTVILSTHQMELVEELCDRVLLLNKGRAVLYG 210
|
|
| LptB |
COG1137 |
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope ... |
1-223 |
4.29e-42 |
|
ABC-type lipopolysaccharide export system, ATPase component [Cell wall/membrane/envelope biogenesis];
Pssm-ID: 440752 [Multi-domain] Cd Length: 240 Bit Score: 146.33 E-value: 4.29e-42
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALP--ERelt 78
Cdd:COG1137 3 TLEAENLVKSYGK----RTVVKDVSLEVNQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGRIFLDGEDITHLPmhKR--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 lARRQIGM------IFQhfNLlssrTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIA 152
Cdd:COG1137 76 -ARLGIGYlpqeasIFR--KL----TVEDNILAVLELRKLSKKEREERLEELLEEFGITHLRKSKAYSLSGGERRRVEIA 148
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTT---RSILSLLKEinvkLGLTIlLIT-HEmdvVK---GICDDVAIISDGSLIEQG 223
Cdd:COG1137 149 RALATNPKFILLDEPFAGVDPIAVadiQKIIRHLKE----RGIGV-LITdHN---VRetlGICDRAYIISEGKVLAEG 218
|
|
| ABC_Carb_Monos_I |
cd03216 |
First domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
2-220 |
2.13e-41 |
|
First domain of the ATP-binding cassette component of monosaccharide transport system; This family represents the domain I of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. Pentoses include xylose, arabinose, and ribose. Important hexoses include glucose, galactose, and fructose. In members of the Carb_monos family, the single hydrophobic gene product forms a homodimer while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213183 [Multi-domain] Cd Length: 163 Bit Score: 142.18 E-value: 2.13e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlAR 81
Cdd:cd03216 1 LELRGITKRFG----GVKALDGVSLSVRRGEVHALLGENGAGKSTLMKILSGLYKPDSGEILVDGKEVSFASPRD---AR 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQ-IGMIFQhfnllssrtvfaniafplelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPAPK 160
Cdd:cd03216 74 RAgIAMVYQ---------------------------------------------------LSVGERQMVEIARALARNAR 102
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:cd03216 103 LLILDEPTAALTPAEVERLFKVIRRL-RAQGVAVIFISHRLDEVFEIADRVTVLRDGRVV 161
|
|
| PRK11831 |
PRK11831 |
phospholipid ABC transporter ATP-binding protein MlaF; |
23-253 |
4.04e-41 |
|
phospholipid ABC transporter ATP-binding protein MlaF;
Pssm-ID: 236997 [Multi-domain] Cd Length: 269 Bit Score: 144.91 E-value: 4.04e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQHFNLLSSRTVFAN 102
Cdd:PRK11831 25 NISLTVPRGKITAIMGPSGIGKTTLLRLIGGQIAPDHGEILFDGENIPAMSRSRLYTVRKRMSMLFQSGALFTDMNVFDN 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 103 IAFPL-ELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILS 181
Cdd:PRK11831 105 VAYPLrEHTQLPAPLLHSTVMMKLEAVGLRGAAKLMPSELSGGMARRAALARAIALEPDLIMFDEPFVGQDPITMGVLVK 184
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 182 LLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLaRDFIHSTIHLEVPQEY 253
Cdd:PRK11831 185 LISELNSALGVTCVVVSHDVPEVLSIADHAYIVADKKIVAHGSAQALQANPDPRV-RQFLDGIADGPVPFRY 255
|
|
| cbiO |
PRK13646 |
energy-coupling factor transporter ATPase; |
2-250 |
4.26e-41 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184205 [Multi-domain] Cd Length: 286 Bit Score: 145.31 E-value: 4.26e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVH-ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVA-LPERELTL 79
Cdd:PRK13646 3 IRFDNVSYTYQKGTPYEHqAIHDVNTEFEQGKYYAIVGQTGSGKSTLIQNINALLKPTTGTVTVDDITITHkTKDKYIRP 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQhF--NLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAY-PSELSGGQKQRVAIARALA 156
Cdd:PRK13646 83 VRKRIGMVFQ-FpeSQLFEDTVEREIIFGPKNFKMNLDEVKNYAHRLLMDLGFSRDVMSQsPFQMSGGQMRKIAIVSILA 161
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNaKTQL 236
Cdd:PRK13646 162 MNPDIIVLDEPTAGLDPQSKRQVMRLLKSLQTDENKTIILVSHDMNEVARYADEVIVMKEGSIVSQTSPKELFKD-KKKL 240
|
250
....*....|....
gi 754651031 237 ARdfihstIHLEVP 250
Cdd:PRK13646 241 AD------WHIGLP 248
|
|
| cbiO |
PRK13634 |
cobalt transporter ATP-binding subunit; Provisional |
20-223 |
6.03e-41 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237454 [Multi-domain] Cd Length: 290 Bit Score: 145.16 E-value: 6.03e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVA-LPERELTLARRQIGMIFQhF--NLLSS 96
Cdd:PRK13634 22 ALYDVNVSIPSGSYVAIIGHTGSGKSTLLQHLNGLLQPTSGTVTIGERVITAgKKNKKLKPLRKKVGIVFQ-FpeHQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQ 174
Cdd:PRK13634 101 ETVEKDICFgPMNF-GVSEEDAKQKAREMIELVGLpEELLARSPFELSGGQMRRVAIAGVLAMEPEVLVLDEPTAGLDPK 179
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 754651031 175 TTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK13634 180 GRKEMMEMFYKLHKEKGLTTVLVTHSMEDAARYADQIVVMHKGTVFLQG 228
|
|
| ABC_YhbG |
cd03218 |
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the ... |
2-233 |
9.20e-41 |
|
ATP-binding cassette component of YhbG transport system; The ABC transporters belonging to the YhbG family are similar to members of the Mj1267_LivG family, which is involved in the transport of branched-chain amino acids. The genes yhbG and yhbN are located in a single operon and may function together in cell envelope during biogenesis. YhbG is the putative ATP-binding cassette component and YhbN is the putative periplasmic-binding protein. Depletion of each gene product leads to growth arrest, irreversible cell damage and loss of viability in E. coli. The YhbG homolog (NtrA) is essential in Rhizobium meliloti, a symbiotic nitrogen-fixing bacterium.
Pssm-ID: 213185 [Multi-domain] Cd Length: 232 Bit Score: 142.68 E-value: 9.20e-41
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALP--EReltl 79
Cdd:cd03218 1 LRAENLSKRYGKR----KVVNGVSLSVKQGEIVGLLGPNGAGKTTTFYMIVGLVKPDSGKILLDGQDITKLPmhKR---- 72
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:cd03218 73 ARLGIGYLPQEASIFRKLTVEENILAVLEIRGLSKKEREEKLEELLEEFHITHLRKSKASSLSGGERRRVEIARALATNP 152
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:cd03218 153 KFLLLDEPFAGVDPIAVQDIQKIIKILKDR-GIGVLITDHNVRETLSITDRAYIIYEGKVLAEGTPEEIAANEL 225
|
|
| cbiO |
PRK13648 |
cobalt transporter ATP-binding subunit; Provisional |
15-233 |
3.31e-40 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184207 [Multi-domain] Cd Length: 269 Bit Score: 142.58 E-value: 3.31e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 15 SDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERELTLARRQIGMIFQH-FNL 93
Cdd:PRK13648 19 SDASFTLKDVSFNIPKGQWTSIVGHNGSGKSTIAKLMIGIEKVKSGEIFYNNQ---AITDDNFEKLRKHIGIVFQNpDNQ 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:PRK13648 96 FVGSIVKYDVAFGLENHAVPYDEMHRRVSEALKQVDMLERADYEPNALSGGQKQRVAIAGVLALNPSVIILDEATSMLDP 175
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 174 QTTRSILSLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:PRK13648 176 DARQNLLDLVRKVKSEHNITIISITHDLSEAME-ADHVIVMNKGTVYKEGTPTEIFDHAE 234
|
|
| cbiO |
PRK13649 |
energy-coupling factor transporter ATPase; |
20-251 |
4.78e-40 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184208 [Multi-domain] Cd Length: 280 Bit Score: 142.19 E-value: 4.78e-40
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPE-RELTLARRQIGMIFQhF--NLLSS 96
Cdd:PRK13649 22 ALFDVNLTIEDGSYTAFIGHTGSGKSTIMQLLNGLHVPTQGSVRVDDTLITSTSKnKDIKQIRKKVGLVFQ-FpeSQLFE 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAFPLELAGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:PRK13649 101 ETVLKDVAFGPQNFGVSQEEAEALAREKLALVGIsESLFEKNPFELSGGQMRRVAIAGILAMEPKILVLDEPTAGLDPKG 180
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 176 TRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAktqlarDFIHStIHLEVPQ 251
Cdd:PRK13649 181 RKELMTLFKKLH-QSGMTIVLVTHLMDDVANYADFVYVLEKGKLVLSGKPKDIFQDV------DFLEE-KQLGVPK 248
|
|
| ssuB |
PRK11247 |
aliphatic sulfonates transport ATP-binding subunit; Provisional |
4-217 |
1.73e-39 |
|
aliphatic sulfonates transport ATP-binding subunit; Provisional
Pssm-ID: 183055 [Multi-domain] Cd Length: 257 Bit Score: 140.20 E-value: 1.73e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlpereltlARRQ 83
Cdd:PRK11247 15 LNAVSKRYGERT----VLNQLDLHIPAGQFVAVVGRSGCGKSTLLRLLAGLETPSAGELLAGTAPLAE--------ARED 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 84 IGMIFQHFNLLSSRTVFANIAfpLELAG-WsksqiRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVL 162
Cdd:PRK11247 83 TRLMFQDARLLPWKKVIDNVG--LGLKGqW-----RDAALQALAAVGLADRANEWPAALSGGQKQRVALARALIHRPGLL 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 163 LCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:PRK11247 156 LLDEPLGALDALTRIEMQDLIESLWQQHGFTVLLVTHDVSEAVAMADRVLLIEEG 210
|
|
| ABC_MTABC3_MDL1_MDL2 |
cd03249 |
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 ... |
18-223 |
2.04e-39 |
|
ATP-binding cassette domain of a mitochondrial protein MTABC3 and related proteins; MTABC3 (also known as ABCB6) is a mitochondrial ATP-binding cassette protein involved in iron homeostasis and one of four ABC transporters expressed in the mitochondrial inner membrane, the other three being MDL1(ABC7), MDL2, and ATM1. In fact, the yeast MDL1 (multidrug resistance-like protein 1) and MDL2 (multidrug resistance-like protein 2) transporters are also included in this CD. MDL1 is an ATP-dependent permease that acts as a high-copy suppressor of ATM1 and is thought to have a role in resistance to oxidative stress. Interestingly, subfamily B is more closely related to the carboxyl-terminal component of subfamily C than the two halves of ABCC molecules are with one another.
Pssm-ID: 213216 [Multi-domain] Cd Length: 238 Bit Score: 139.60 E-value: 2.04e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTlirCVNLLER---PTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLL 94
Cdd:cd03249 16 VPILKGLSLTIPPGKTVALVGSSGCGKST---VVSLLERfydPTSGEILLDGVDIRDLNLRWL---RSQIGLVSQEPVLF 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 sSRTVFANIAFPLELAGWSKSQIRARVDELLALV-----GLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:cd03249 90 -DGTIAENIRYGKPDATDEEVEEAAKKANIHDFImslpdGYDTLVGERGSQLSGGQKQRIAIARALLRNPKILLLDEATS 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 754651031 170 ALDPQTTRSILSLLKeiNVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03249 169 ALDAESEKLVQEALD--RAMKGRTTIVIAHRLSTIRN-ADLIAVLQNGQVVEQG 219
|
|
| PRK14246 |
PRK14246 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-241 |
2.89e-39 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172734 [Multi-domain] Cd Length: 257 Bit Score: 139.80 E-value: 2.89e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL------ERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLL 94
Cdd:PRK14246 26 LKDITIKIPNNSIFGIMGPSGSGKSTLLKVLNRLieiydsKIKVDGKVLYFGKDIFQIDAIKL---RKEVGMVFQQPNPF 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANIAFPLELAGWS-KSQIRARVDELLALVGLEARAH----AYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:PRK14246 103 PHLSIYDNIAYPLKSHGIKeKREIKKIVEECLRKVGLWKEVYdrlnSPASQLSGGQQQRLTIARALALKPKVLLMDEPTS 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 170 ALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFI 241
Cdd:PRK14246 183 MIDIVNSQAIEKLITEL--KNEIAIVIVSHNPQQVARVADYVAFLYNGELVEWGSSNEIFTSPKNELTEKYV 252
|
|
| cbiO |
PRK13640 |
energy-coupling factor transporter ATPase; |
20-231 |
2.90e-39 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184200 [Multi-domain] Cd Length: 282 Bit Score: 140.32 E-value: 2.90e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERP---TEGQVIVDGqdlVALPERELTLARRQIGMIFQH-FNLLS 95
Cdd:PRK13640 22 ALNDISFSIPRGSWTALIGHNGSGKSTISKLINGLLLPddnPNSKITVDG---ITLTAKTVWDIREKVGIVFQNpDNQFV 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:PRK13640 99 GATVGDDVAFGLENRAVPRPEMIKIVRDVLADVGMLDYIDSEPANLSGGQKQRVAIAGILAVEPKIIILDESTSMLDPAG 178
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 176 TRSILSLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSN 231
Cdd:PRK13640 179 KEQILKLIRKLKKKNNLTVISITHDIDEANM-ADQVLVLDDGKLLAQGSPVEIFSK 233
|
|
| CcmA |
COG4133 |
ABC-type transport system involved in cytochrome c biogenesis, ATPase component ... |
1-200 |
3.25e-39 |
|
ABC-type transport system involved in cytochrome c biogenesis, ATPase component [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 443308 [Multi-domain] Cd Length: 206 Bit Score: 138.00 E-value: 3.25e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEReltlA 80
Cdd:COG4133 2 MLEAENLSCRRGE----RLLFSGLSFTLAAGEALALTGPNGSGKTTLLRILAGLLPPSAGEVLWNGEPIRDARED----Y 73
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSqiRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG4133 74 RRRLAYLGHADGLKPELTVRENLRFWAALYGLRAD--REAIDEALEAVGLAGLADLPVRQLSAGQKRRVALARLLLSPAP 151
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEiNVKLGLTILLITHE 200
Cdd:COG4133 152 LWLLDEPFTALDAAGVALLAELIAA-HLARGGAVLLTTHQ 190
|
|
| ABCC_MsbA |
cd03251 |
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; ... |
8-223 |
3.42e-39 |
|
ATP-binding cassette domain of the bacterial lipid flippase and related proteins, subfamily C; MsbA is an essential ABC transporter, closely related to eukaryotic MDR proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213218 [Multi-domain] Cd Length: 234 Bit Score: 138.90 E-value: 3.42e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 8 NKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLER---PTEGQVIVDGQDLvalpeRELTLA--RR 82
Cdd:cd03251 5 NVTFRYPGDGPPVLRDISLDIPAGETVALVGPSGSGKSTL---VNLIPRfydVDSGRILIDGHDV-----RDYTLAslRR 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIGMIFQHFNLLSSrTVFANIAFPLELAgwSKSQIR--ARVDELLALV-----GLEARAHAYPSELSGGQKQRVAIARAL 155
Cdd:cd03251 77 QIGLVSQDVFLFND-TVAENIAYGRPGA--TREEVEeaARAANAHEFImelpeGYDTVIGERGVKLSGGQRQRIAIARAL 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGIcDDVAIISDGSLIEQG 223
Cdd:cd03251 154 LKDPPILILDEATSALDTESERLVQAALERLMK--NRTTFVIAHRLSTIENA-DRIVVLEDGKIVERG 218
|
|
| ABCC_Hemolysin |
cd03252 |
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a ... |
14-223 |
3.68e-39 |
|
ATP-binding cassette domain of hemolysin B, subfamily C; The ABC-transporter hemolysin B is a central component of the secretion machinery that translocates the toxin, hemolysin A, in a Sec-independent fashion across both membranes of E. coli. The hemolysin A (HlyA) transport machinery is composed of the ATP-binding cassette (ABC) transporter HlyB located in the inner membrane, hemolysin D (HlyD), also anchored in the inner membrane, and TolC, which resides in the outer membrane. HlyD apparently forms a continuous channel that bridges the entire periplasm, interacting with TolC and HlyB. This arrangement prevents the appearance of periplasmic intermediates of HlyA during substrate transport. Little is known about the molecular details of HlyA transport, but it is evident that ATP-hydrolysis by the ABC-transporter HlyB is a necessary source of energy.
Pssm-ID: 213219 [Multi-domain] Cd Length: 237 Bit Score: 138.77 E-value: 3.68e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 14 GSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALperELTLARRQIGMIFQHfNL 93
Cdd:cd03252 11 KPDGPVILDNISLRIKPGEVVGIVGRSGSGKSTLTKLIQRFYVPENGRVLVDGHDLALA---DPAWLRRQVGVVLQE-NV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSRTVFANIAFPLELAGwsksqiRARVDELLALVGlearAHAYPSE---------------LSGGQKQRVAIARALAPA 158
Cdd:cd03252 87 LFNRSIRDNIALADPGMS------MERVIEAAKLAG----AHDFISElpegydtivgeqgagLSGGQRQRIAIARALIHN 156
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 159 PKVLLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03252 157 PRILIFDEATSALDYESEHAIMRNMHDICA--GRTVIIIAHRLSTVKN-ADRIIVMEKGRIVEQG 218
|
|
| cbiO |
PRK13652 |
cobalt transporter ATP-binding subunit; Provisional |
15-250 |
3.69e-39 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 172200 [Multi-domain] Cd Length: 277 Bit Score: 139.94 E-value: 3.69e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 15 SDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFN-L 93
Cdd:PRK13652 14 SGSKEALNNINFIAPRNSRIAVIGPNGAGKSTLFRHFNGILKPTSGSVLIRGEPITKENIREV---RKFVGLVFQNPDdQ 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSRTVFANIAF-PLELaGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK13652 91 IFSPTVEQDIAFgPINL-GLDEETVAHRVSSALHMLGLEELRDRVPHHLSGGEKKRVAIAGVIAMEPQVLVLDEPTAGLD 169
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 173 PQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSnaktqlaRDFIHSTIHLEVP 250
Cdd:PRK13652 170 PQGVKELIDFLNDLPETYGMTVIFSTHQLDLVPEMADYIYVMDKGRIVAYGTVEEIFL-------QPDLLARVHLDLP 240
|
|
| PRK14239 |
PRK14239 |
phosphate transporter ATP-binding protein; Provisional |
1-241 |
7.37e-39 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184585 [Multi-domain] Cd Length: 252 Bit Score: 138.37 E-value: 7.37e-39
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL-----ERPTEGQVIVDGQDLVAlPER 75
Cdd:PRK14239 5 ILQVSDLSVYYNKKK----ALNSVSLDFYPNEITALIGPSGSGKSTLLRSINRMndlnpEVTITGSIVYNGHNIYS-PRT 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 76 ELTLARRQIGMIFQHFNLLSSrTVFANIAFPLELAGWSKsqiRARVDELL--ALVG------LEARAHAYPSELSGGQKQ 147
Cdd:PRK14239 80 DTVDLRKEIGMVFQQPNPFPM-SIYENVVYGLRLKGIKD---KQVLDEAVekSLKGasiwdeVKDRLHDSALGLSGGQQQ 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 148 RVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLkeINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAW 227
Cdd:PRK14239 156 RVCIARVLATSPKIILLDEPTSALDPISAGKIEETL--LGLKDDYTMLLVTRSMQQASRISDRTGFFLDGDLIEYNDTKQ 233
|
250
....*....|....
gi 754651031 228 FFSNAKTQLARDFI 241
Cdd:PRK14239 234 MFMNPKHKETEDYI 247
|
|
| cbiO |
PRK13647 |
cobalt transporter ATP-binding subunit; Provisional |
16-257 |
1.13e-38 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237457 [Multi-domain] Cd Length: 274 Bit Score: 138.71 E-value: 1.13e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 16 DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQH-FNLL 94
Cdd:PRK13647 16 DGTKALKGLSLSIPEGSKTALLGPNGAGKSTLLLHLNGIYLPQRGRVKVMGREVNAENEKWV---RSKVGLVFQDpDDQV 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANIAF-PLELaGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:PRK13647 93 FSSTVWDDVAFgPVNM-GLDKDEVERRVEEALKAVRMWDFRDKPPYHLSYGQKKRVAIAGVLAMDPDVIVLDEPMAYLDP 171
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 174 QTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLA--RDFIHSTIHLEVPQ 251
Cdd:PRK13647 172 RGQETLMEILDRLH-NQGKTVIVATHDVDLAAEWADQVIVLKEGRVLAEGDKSLLTDEDIVEQAglRLPLVAQIFEDLPE 250
|
....*.
gi 754651031 252 EYQDRL 257
Cdd:PRK13647 251 LGQSKL 256
|
|
| PRK10584 |
PRK10584 |
putative ABC transporter ATP-binding protein YbbA; Provisional |
7-222 |
1.26e-38 |
|
putative ABC transporter ATP-binding protein YbbA; Provisional
Pssm-ID: 182569 [Multi-domain] Cd Length: 228 Bit Score: 137.22 E-value: 1.26e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 7 LNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR-RQIG 85
Cdd:PRK10584 12 LKKSVGQGEHELSILTGVELVVKRGETIALIGESGSGKSTLLAILAGLDDGSSGEVSLVGQPLHQMDEEARAKLRaKHVG 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 86 MIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:PRK10584 92 FVFQSFMLIPTLNALENVELPALLRGESSRQSRNGAKALLEQLGLGKRLDHLPAQLSGGEQQRVALARAFNGRPDVLFAD 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 166 EATSALDPQTTRSILSLLKEINVKLGLTILLITHEmDVVKGICDDVAIISDGSLIEQ 222
Cdd:PRK10584 172 EPTGNLDRQTGDKIADLLFSLNREHGTTLILVTHD-LQLAARCDRRLRLVNGQLQEE 227
|
|
| PhnK |
COG1101 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-201 |
1.55e-38 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 440718 [Multi-domain] Cd Length: 264 Bit Score: 137.91 E-value: 1.55e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGS-DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltl 79
Cdd:COG1101 1 MLELKNLSKTFNPGTvNEKRALDGLNLTIEEGDFVTVIGSNGAGKSTLLNAIAGSLPPDSGSILIDGKDVTKLPEYK--- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 aR-RQIGMIFQhfNLL----SSRTVFANIAfpleLA-------GWSKSQIRARVD---ELLALV--GLEARAHAYPSELS 142
Cdd:COG1101 78 -RaKYIGRVFQ--DPMmgtaPSMTIEENLA----LAyrrgkrrGLRRGLTKKRRElfrELLATLglGLENRLDTKVGLLS 150
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 143 GGQKQRVAIARA-LAPaPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEM 201
Cdd:COG1101 151 GGQRQALSLLMAtLTK-PKLLLLDEHTAALDPKTAALVLELTEKIVEENNLTTLMVTHNM 209
|
|
| YnjD |
COG4136 |
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function ... |
21-202 |
3.39e-38 |
|
ABC-type uncharacterized transport system YnjBCD, ATPase component [General function prediction only];
Pssm-ID: 443311 [Multi-domain] Cd Length: 211 Bit Score: 135.30 E-value: 3.39e-38
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVN-LLERP--TEGQVIVDGQDLVALPEReltlaRRQIGMIFQ------HF 91
Cdd:COG4136 17 LAPLSLTVAPGEILTLMGPSGSGKSTLLAAIAgTLSPAfsASGEVLLNGRRLTALPAE-----QRRIGILFQddllfpHL 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 NllssrtVFANIAFPLElAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSAL 171
Cdd:COG4136 92 S------VGENLAFALP-PTIGRAQRRARVEQALEEAGLAGFADRDPATLSGGQRARVALLRALLAEPRALLLDEPFSKL 164
|
170 180 190
....*....|....*....|....*....|.
gi 754651031 172 DPQTTRSILSLLKEINVKLGLTILLITHEMD 202
Cdd:COG4136 165 DAALRAQFREFVFEQIRQRGIPALLVTHDEE 195
|
|
| CydD |
COG4988 |
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease ... |
2-226 |
1.23e-37 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444012 [Multi-domain] Cd Length: 563 Bit Score: 141.43 E-value: 1.23e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:COG4988 337 IELEDVSFSYP---GGRPALDGLSLTIPPGERVALVGPSGAGKSTLLNLLLGFLPPYSGSILINGVDLSDLDPASW---R 410
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIAFPLELAgwSKSQI-----RARVDELLALV--GLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:COG4988 411 RQIAWVPQNPYLFAG-TIRENLRLGRPDA--SDEELeaaleAAGLDEFVAALpdGLDTPLGEGGRGLSGGQAQRLALARA 487
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKgICDDVAIISDGSLIEQGEVA 226
Cdd:COG4988 488 LLRDAPLLLLDEPTAHLDAETEAEILQALRRL--AKGRTVILITHRLALLA-QADRILVLDDGRIVEQGTHE 556
|
|
| cbiO |
PRK13644 |
energy-coupling factor transporter ATPase; |
1-235 |
1.81e-37 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 106587 [Multi-domain] Cd Length: 274 Bit Score: 135.50 E-value: 1.81e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYgkgSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlvALPERELTLA 80
Cdd:PRK13644 1 MIRLENVSYSY---PDGTPALENINLVIKKGEYIGIIGKNGSGKSTLALHLNGLLRPQKGKVLVSGID--TGDFSKLQGI 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNL-LSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK13644 76 RKLVGIVFQNPETqFVGRTVEEDLAFGPENLCLPPIEIRKRVDRALAEIGLEKYRHRSPKTLSGGQGQCVALAGILTMEP 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKgICDDVAIISDGSLIEQGEVAWFFSNAKTQ 235
Cdd:PRK13644 156 ECLIFDEVTSMLDPDSGIAVLERIKKLHEK-GKTIVYITHNLEELH-DADRIIVMDRGKIVLEGEPENVLSDVSLQ 229
|
|
| ABCC_ATM1_transporter |
cd03253 |
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC ... |
21-223 |
1.92e-37 |
|
ATP-binding cassette domain of iron-sulfur clusters transporter, subfamily C; ATM1 is an ABC transporter that is expressed in the mitochondria. Although the specific function of ATM1 is unknown, its disruption results in the accumulation of excess mitochondrial iron, loss of mitochondrial cytochromes, oxidative damage to mitochondrial DNA, and decreased levels of cytosolic heme proteins. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds, like sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213220 [Multi-domain] Cd Length: 236 Bit Score: 134.28 E-value: 1.92e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRcvnLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQH---FN 92
Cdd:cd03253 17 LKDVSFTIPAGKKVAIVGPSGSGKSTILR---LLFRfydVSSGSILIDGQDI-----REVTLDslRRAIGVVPQDtvlFN 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 llssRTVFANIAFPLELAgwSKSQIR-----ARVDELLalvglEARAHAYPSE-------LSGGQKQRVAIARALAPAPK 160
Cdd:cd03253 89 ----DTIGYNIRYGRPDA--TDEEVIeaakaAQIHDKI-----MRFPDGYDTIvgerglkLSGGEKQRVAIARAILKNPP 157
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03253 158 ILLLDEATSALDTHTEREIQAALRDVSK--GRTTIVIAHRLSTIVN-ADKIIVLKDGRIVERG 217
|
|
| cbiO |
PRK13645 |
energy-coupling factor transporter ATPase; |
2-254 |
2.25e-37 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184204 [Multi-domain] Cd Length: 289 Bit Score: 135.52 E-value: 2.25e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPER--ELT 78
Cdd:PRK13645 7 IILDNVSYTYAKKTPfEFKALNNTSLTFKKNKVTCVIGTTGSGKSTMIQLTNGLIISETGQTIVGDYAIPANLKKikEVK 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 LARRQIGMIFQ--HFNLLSSrTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARA 154
Cdd:PRK13645 87 RLRKEIGLVFQfpEYQLFQE-TIEKDIAFgPVNL-GENKQEAYKKVPELLKLVQLpEDYVKRSPFELSGGQKRRVALAGI 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKt 234
Cdd:PRK13645 165 IAMDGNTLVLDEPTGGLDPKGEEDFINLFERLNKEYKKRIIMVTHNMDQVLRIADEVIVMHEGKVISIGSPFEIFSNQE- 243
|
250 260
....*....|....*....|
gi 754651031 235 qlardfIHSTIHLEVPQEYQ 254
Cdd:PRK13645 244 ------LLTKIEIDPPKLYQ 257
|
|
| PRK14258 |
PRK14258 |
phosphate ABC transporter ATP-binding protein; Provisional |
2-245 |
2.51e-37 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 184593 [Multi-domain] Cd Length: 261 Bit Score: 134.78 E-value: 2.51e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYgkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL-----ERPTEGQVIVDGQDLValpERE 76
Cdd:PRK14258 8 IKVNNLSFYY----DTQKILEGVSMEIYQSKVTAIIGPSGCGKSTFLKCLNRMnelesEVRVEGRVEFFNQNIY---ERR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTL--ARRQIGMIFQHFNLLSsRTVFANIAFPLELAGW-SKSQIRARVDELLALVGL----EARAHAYPSELSGGQKQRV 149
Cdd:PRK14258 81 VNLnrLRRQVSMVHPKPNLFP-MSVYDNVAYGVKIVGWrPKLEIDDIVESALKDADLwdeiKHKIHKSALDLSGGQQQRL 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISD-----GSLIEQGE 224
Cdd:PRK14258 160 CIARALAVKPKVLLMDEPCFGLDPIASMKVESLIQSLRLRSELTMVIVSHNLHQVSRLSDFTAFFKGnenriGQLVEFGL 239
|
250 260
....*....|....*....|.
gi 754651031 225 VAWFFSNAKTQLARDFIHSTI 245
Cdd:PRK14258 240 TKKIFNSPHDSRTREYVLSRL 260
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
19-241 |
3.35e-37 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 139.84 E-value: 3.35e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKST----LIRCVNllerpTEGQVIVDGQDLVALPERELTLARRQIGMIFQHFN-L 93
Cdd:PRK15134 300 VVVKNISFTLRPGETLGLVGESGSGKSTtglaLLRLIN-----SQGEIWFDGQPLHNLNRRQLLPVRHRIQVVFQDPNsS 374
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSR-TVFANIAFPLEL--AGWSKSQIRARVDELLALVGLEARA-HAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:PRK15134 375 LNPRlNVLQIIEEGLRVhqPTLSAAQREQQVIAVMEEVGLDPETrHRYPAEFSGGQRQRIAIARALILKPSLIILDEPTS 454
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 170 ALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFI 241
Cdd:PRK15134 455 SLDKTVQAQILALLKSLQQKHQLAYLFISHDLHVVRALCHQVIVLRQGEVVEQGDCERVFAAPQQEYTRQLL 526
|
|
| modC_ABC |
TIGR02142 |
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding ... |
23-226 |
3.43e-37 |
|
molybdenum ABC transporter, ATP-binding protein; This model represents the ATP-binding cassette (ABC) protein of the three subunit molybdate ABC transporter. The three proteins of this complex are homologous to proteins of the sulfate ABC transporter. Molybdenum may be used in nitrogenases of nitrogen-fixing bacteria and in molybdopterin cofactors. In some cases, molybdate may be transported by a sulfate transporter rather than by a specific molybdate transporter. [Transport and binding proteins, Anions]
Pssm-ID: 131197 [Multi-domain] Cd Length: 354 Bit Score: 136.78 E-value: 3.43e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPER-ELTLARRQIGMIFQHFNLLSSRTVFA 101
Cdd:TIGR02142 15 DADFTLPGQGVTAIFGRSGSGKTTLIRLIAGLTRPDEGEIVLNGRTLFDSRKGiFLPPEKRRIGYVFQEARLFPHLSVRG 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 102 NIAFPLELAgwSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILS 181
Cdd:TIGR02142 95 NLRYGMKRA--RPSERRISFERVIELLGIGHLLGRLPGRLSGGEKQRVAIGRALLSSPRLLLMDEPLAALDDPRKYEILP 172
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 754651031 182 LLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:TIGR02142 173 YLERLHAEFGIPILYVSHSLQEVLRLADRVVVLEDGRVAAAGPIA 217
|
|
| tauB |
PRK11248 |
taurine ABC transporter ATP-binding subunit; |
20-202 |
8.04e-37 |
|
taurine ABC transporter ATP-binding subunit;
Pssm-ID: 183056 [Multi-domain] Cd Length: 255 Bit Score: 133.29 E-value: 8.04e-37
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPERELtlarrqiGMIFQHFNLLSSRTV 99
Cdd:PRK11248 16 ALEDINLTLESGELLVVLGPSGCGKTTLLNLIAGFVPYQHGSITLDGKP-VEGPGAER-------GVVFQNEGLLPWRNV 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSI 179
Cdd:PRK11248 88 QDNVAFGLQLAGVEKMQRLEIAHQMLKKVGLEGAEKRYIWQLSGGQRQRVGIARALAANPQLLLLDEPFGALDAFTREQM 167
|
170 180
....*....|....*....|...
gi 754651031 180 LSLLKEINVKLGLTILLITHEMD 202
Cdd:PRK11248 168 QTLLLKLWQETGKQVLLITHDIE 190
|
|
| PRK13651 |
PRK13651 |
cobalt transporter ATP-binding subunit; Provisional |
2-224 |
1.59e-36 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 184210 [Multi-domain] Cd Length: 305 Bit Score: 133.67 E-value: 1.59e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQV---IVDGQDLVALPEREL 77
Cdd:PRK13651 3 IKVKNIVKIFNKKLPtELKALDNVSVEINQGEFIAIIGQTGSGKTTFIEHLNALLLPDTGTIewiFKDEKNKKKTKEKEK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 78 TLA------------------RRQIGMIFQ--HFNLLSSrTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAH 135
Cdd:PRK13651 83 VLEklviqktrfkkikkikeiRRRVGVVFQfaEYQLFEQ-TIEKDIIFgPVSM-GVSKEEAKKRAAKYIELVGLdESYLQ 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 136 AYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIIS 215
Cdd:PRK13651 161 RSPFELSGGQKRRVALAGILAMEPDFLVFDEPTAGLDPQGVKEILEIFDNLN-KQGKTIILVTHDLDNVLEWTKRTIFFK 239
|
....*....
gi 754651031 216 DGSLIEQGE 224
Cdd:PRK13651 240 DGKIIKDGD 248
|
|
| ATM1 |
COG5265 |
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components ... |
21-223 |
9.87e-36 |
|
ABC-type transport system involved in Fe-S cluster assembly, permease and ATPase components [Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444078 [Multi-domain] Cd Length: 605 Bit Score: 136.49 E-value: 9.87e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRcvnLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQH---FN 92
Cdd:COG5265 374 LKGVSFEVPAGKTVAIVGPSGAGKSTLAR---LLFRfydVTSGRILIDGQDI-----RDVTQAslRAAIGIVPQDtvlFN 445
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 llssRTVFANIAFPLELAgwSKSQIR-----ARVDELLA--------LVGlearahaypsE----LSGGQKQRVAIARAL 155
Cdd:COG5265 446 ----DTIAYNIAYGRPDA--SEEEVEaaaraAQIHDFIEslpdgydtRVG----------ErglkLSGGEKQRVAIARTL 509
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEinVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:COG5265 510 LKNPPILIFDEATSALDSRTERAIQAALRE--VARGRTTLVIAHRLSTIVD-ADEILVLEAGRIVERG 574
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
18-231 |
1.17e-35 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 136.52 E-value: 1.17e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQ--HFNLLS 95
Cdd:PRK10261 337 VHAVEKVSFDLWPGETLSLVGESGSGKSTTGRALLRLVESQGGEIIFNGQRIDTLSPGKLQALRRDIQFIFQdpYASLDP 416
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SRTVFANIAFPLELAGWSKSQ-IRARVDELLALVGLEARaHA--YPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK10261 417 RQTVGDSIMEPLRVHGLLPGKaAAARVAWLLERVGLLPE-HAwrYPHEFSGGQRQRICIARALALNPKVIIADEAVSALD 495
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 173 PQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSN 231
Cdd:PRK10261 496 VSIRGQIINLLLDLQRDFGIAYLFISHDMAVVERISHRVAVMYLGQIVEIGPRRAVFEN 554
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
1-224 |
1.92e-35 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 134.93 E-value: 1.92e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVY---GKGsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVD-GQDLVALPERE 76
Cdd:TIGR03269 279 IIKVRNVSKRYisvDRG--VVKAVDNVSLEVKEGEIFGIVGTSGAGKTTLSKIIAGVLEPTSGEVNVRvGDEWVDMTKPG 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTL---ARRQIGMIFQHFNLLSSRTVFAN------IAFPLELAgwsksqiRARVDELLALVGL-EARAHA----YPSELS 142
Cdd:TIGR03269 357 PDGrgrAKRYIGILHQEYDLYPHRTVLDNlteaigLELPDELA-------RMKAVITLKMVGFdEEKAEEildkYPDELS 429
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 143 GGQKQRVAIARALAPAPKVLLCDEATSALDPQT----TRSILSLLKEINVklglTILLITHEMDVVKGICDDVAIISDGS 218
Cdd:TIGR03269 430 EGERHRVALAQVLIKEPRIVILDEPTGTMDPITkvdvTHSILKAREEMEQ----TFIIVSHDMDFVLDVCDRAALMRDGK 505
|
....*.
gi 754651031 219 LIEQGE 224
Cdd:TIGR03269 506 IVKIGD 511
|
|
| PRK13537 |
PRK13537 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-261 |
2.80e-35 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237420 [Multi-domain] Cd Length: 306 Bit Score: 130.31 E-value: 2.80e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERElTLAR 81
Cdd:PRK13537 8 IDFRNVEKRYGDKL----VVDGLSFHVQRGECFGLLGPNGAGKTTTLRMLLGLTHPDAGSISLCGE---PVPSRA-RHAR 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:PRK13537 80 QRVGVVPQFDNLDPDFTVRENLLVFGRYFGLSAAAARALVPPLLEFAKLENKADAKVGELSGGMKRRLTLARALVNDPDV 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEvawffsnaktqlARDFI 241
Cdd:PRK13537 160 LVLDEPTTGLDPQARHLMWERLRSL-LARGKTILLTTHFMEEAERLCDRLCVIEEGRKIAEGA------------PHALI 226
|
250 260
....*....|....*....|
gi 754651031 242 HSTIHLEVPQEYQDRLSAER 261
Cdd:PRK13537 227 ESEIGCDVIEIYGPDPVALR 246
|
|
| CeuD |
COG4604 |
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and ... |
1-226 |
3.03e-35 |
|
ABC-type enterochelin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443654 [Multi-domain] Cd Length: 252 Bit Score: 128.66 E-value: 3.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltLA 80
Cdd:COG4604 1 MIEIKNVSKRYG--GKVV--LDDVSLTIPKGGITALIGPNGAGKSTLLSMISRLLPPDSGEVLVDGLDVATTPSRE--LA 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRqIGMIFQHfNLLSSR-TVFANIAF---PlelagWSKSQI----RARVDELLALVGLEARAHAYPSELSGGQKQRVAIA 152
Cdd:COG4604 75 KR-LAILRQE-NHINSRlTVRELVAFgrfP-----YSKGRLtaedREIIDEAIAYLDLEDLADRYLDELSGGQRQRAFIA 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG4604 148 MVLAQDTDYVLLDEPLNNLDMKHSVQMMKLLRRLADELGKTVVIVLHDINFASCYADHIVAMKDGRVVAQGTPE 221
|
|
| PRK14243 |
PRK14243 |
phosphate transporter ATP-binding protein; Provisional |
2-241 |
4.52e-35 |
|
phosphate transporter ATP-binding protein; Provisional
Pssm-ID: 184588 [Multi-domain] Cd Length: 264 Bit Score: 128.75 E-value: 4.52e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLER--PT---EGQVIVDGQDLVAlPERE 76
Cdd:PRK14243 11 LRTENLNVYYGSFL----AVKNVWLDIPKNQITAFIGPSGCGKSTILRCFNRLNDliPGfrvEGKVTFHGKNLYA-PDVD 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQHFNLLSsRTVFANIAFPLELAGWsksqiRARVDELL------ALVGLEARAHAYPS--ELSGGQKQR 148
Cdd:PRK14243 86 PVEVRRRIGMVFQKPNPFP-KSIYDNIAYGARINGY-----KGDMDELVerslrqAALWDEVKDKLKQSglSLSGGQQQR 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 149 VAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGICDDVAIIS---------DGSL 219
Cdd:PRK14243 160 LCIARAIAVQPEVILMDEPCSALDPISTLRIEELMHEL--KEQYTIIIVTHNMQQAARVSDMTAFFNveltegggrYGYL 237
|
250 260
....*....|....*....|..
gi 754651031 220 IEQGEVAWFFSNAKTQLARDFI 241
Cdd:PRK14243 238 VEFDRTEKIFNSPQQQATRDYV 259
|
|
| MsbA_lipidA |
TIGR02203 |
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide ... |
14-223 |
5.03e-35 |
|
lipid A export permease/ATP-binding protein MsbA; This family consists of a single polypeptide chain transporter in the ATP-binding cassette (ABC) transporter family, MsbA, which exports lipid A. It may also act in multidrug resistance. Lipid A, a part of lipopolysaccharide, is found in the outer leaflet of the outer membrane of most Gram-negative bacteria. Members of this family are restricted to the Proteobacteria (although lipid A is more broadly distributed) and often are clustered with lipid A biosynthesis genes. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides, Transport and binding proteins, Other]
Pssm-ID: 131258 [Multi-domain] Cd Length: 571 Bit Score: 134.46 E-value: 5.03e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 14 GSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIF 88
Cdd:TIGR02203 341 PGRDRPALDSISLVIEPGETVALVGRSGSGKSTL---VNLIPRfyePDSGQILLDGHDL-----ADYTLAslRRQVALVS 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 89 QHFNLLSSrTVFANIAFPlELAGWSKSQIR--ARVDELLALV-----GLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:TIGR02203 413 QDVVLFND-TIANNIAYG-RTEQADRAEIEraLAAAYAQDFVdklplGLDTPIGENGVLLSGGQRQRLAIARALLKDAPI 490
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEinVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:TIGR02203 491 LILDEATSALDNESERLVQAALER--LMQGRTTLVIAHRLSTIEK-ADRIVVMDDGRIVERG 549
|
|
| urea_trans_UrtE |
TIGR03410 |
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC ... |
3-226 |
5.11e-35 |
|
urea ABC transporter, ATP-binding protein UrtE; Members of this protein family are ABC transporter ATP-binding subunits associated with urea transport and metabolism. This protein is found in a conserved five-gene transport operon typically found adjacent to urease genes. It was shown in Cyanobacteria that disruption leads to the loss of high-affinity urea transport activity. [Transport and binding proteins, Amino acids, peptides and amines]
Pssm-ID: 274567 [Multi-domain] Cd Length: 230 Bit Score: 127.64 E-value: 5.11e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 3 KLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlARR 82
Cdd:TIGR03410 2 EVSNLNVYYG----QSHILRGVSLEVPKGEVTCVLGRNGVGKTTLLKTLMGLLPVKSGSIRLDGEDITKLPPHER--ARA 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIG------MIFQHFnllssrTVFANIAFPLELAGWSKSQIRARVDELLALvgLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:TIGR03410 76 GIAyvpqgrEIFPRL------TVEENLLTGLAALPRRSRKIPDEIYELFPV--LKEMLGRRGGDLSGGQQQQLAIARALV 147
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:TIGR03410 148 TRPKLLLLDEPTEGIQPSIIKDIGRVIRRLRAEGGMAILLVEQYLDFARELADRYYVMERGRVVASGAGD 217
|
|
| thiQ |
PRK10771 |
thiamine ABC transporter ATP-binding protein ThiQ; |
1-227 |
7.70e-35 |
|
thiamine ABC transporter ATP-binding protein ThiQ;
Pssm-ID: 182716 [Multi-domain] Cd Length: 232 Bit Score: 127.39 E-value: 7.70e-35
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlA 80
Cdd:PRK10771 1 MLKLTDITWLYH------HLPMRFDLTVERGERVAILGPSGAGKSTLLNLIAGFLTPASGSLTLNGQDHTTTPP-----S 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:PRK10771 70 RRPVSMLFQENNLFSHLTVAQNIGLGLNPGLKLNAAQREKLHAIARQMGIEDLLARLPGQLSGGQRQRVALARCLVREQP 149
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMdvvkgicDDVAIISDGSL-IEQGEVAW 227
Cdd:PRK10771 150 ILLLDEPFSALDPALRQEMLTLVSQVCQERQLTLLMVSHSL-------EDAARIAPRSLvVADGRIAW 210
|
|
| CydC |
COG4987 |
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease ... |
20-223 |
2.97e-34 |
|
ABC-type transport system involved in cytochrome bd biosynthesis, fused ATPase and permease components [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];
Pssm-ID: 444011 [Multi-domain] Cd Length: 569 Bit Score: 132.20 E-value: 2.97e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLER---PTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLSS 96
Cdd:COG4987 350 VLDGLSLTLPPGERVAIVGPSGSGKSTL---LALLLRfldPQSGSITLGGVDLRDLDEDDL---RRRIAVVPQRPHLFDT 423
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 rTVFANIAFPLELAGwsksqiRARVDELLALVGLEARAHAYP-----------SELSGGQKQRVAIARA-LAPAPkVLLC 164
Cdd:COG4987 424 -TLRENLRLARPDAT------DEELWAALERVGLGDWLAALPdgldtwlgeggRRLSGGERRRLALARAlLRDAP-ILLL 495
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 165 DEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVkGICDDVAIISDGSLIEQG 223
Cdd:COG4987 496 DEPTEGLDAATEQALLADLLEALA--GRTVLLITHRLAGL-ERMDRILVLEDGRIVEQG 551
|
|
| cbiO |
PRK13643 |
energy-coupling factor transporter ATPase; |
1-274 |
3.70e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184203 [Multi-domain] Cd Length: 288 Bit Score: 127.16 E-value: 3.70e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDgqDLVALP---ERE 76
Cdd:PRK13643 1 MIKFEKVNYTYQPNSPfASRALFDIDLEVKKGSYTALIGHTGSGKSTLLQHLNGLLQPTEGKVTVG--DIVVSStskQKE 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 LTLARRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARA-HAYPSELSGGQKQRVAIARA 154
Cdd:PRK13643 79 IKPVRKKVGVVFQFpESQLFEETVLKDVAFGPQNFGIPKEKAEKIAAEKLEMVGLADEFwEKSPFELSGGQMRRVAIAGI 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAkt 234
Cdd:PRK13643 159 LAMEPEVLVLDEPTAGLDPKARIEMMQLFESIH-QSGQTVVLVTHLMDDVADYADYVYLLEKGHIISCGTPSDVFQEV-- 235
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 754651031 235 qlarDFIHSTiHLEVPQ--EYQDRLSAERVansYPLVKLGFT 274
Cdd:PRK13643 236 ----DFLKAH-ELGVPKatHFADQLQKTGA---VTFEKLPIT 269
|
|
| NHLM_micro_ABC2 |
TIGR03797 |
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family ... |
2-223 |
5.78e-34 |
|
NHLM bacteriocin system ABC transporter, ATP-binding protein; Members of this protein family are ABC transporter ATP-binding subunits, part of a three-gene putative bacteriocin transport operon. The other subunits include another ATP-binding subunit (TIGR03796), which has an N-terminal leader sequence cleavage domain, and an HlyD homolog (TIGR03794). In a number of genomes, members of protein families related to nitrile hydratase alpha subunit or to nif11 have undergone paralogous family expansions, with members possessing a putative bacteriocin cleavage region ending with a classic Gly-Gly motif. Those sets of putative bacteriocins, members of this protein family and its partners TIGR03794 and TIGR03796, and cyclodehydratase/docking scaffold fusion proteins of thiazole/oxazole biosynthesis frequently show correlated species distribution and co-clustering within many of those genomes. [Transport and binding proteins, Amino acids, peptides and amines, Cellular processes, Biosynthesis of natural products]
Pssm-ID: 274789 [Multi-domain] Cd Length: 686 Bit Score: 132.00 E-value: 5.78e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:TIGR03797 452 IEVDRVTFRYRPDGPLI--LDDVSLQIEPGEFVAIVGPSGSGKSTLLRLLLGFETPESGSVFYDGQDLAGLDVQAV---R 526
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIA----FPLELAgWsksqirarvdELLALVGLEA--RA-----HAYPSE----LSGGQK 146
Cdd:TIGR03797 527 RQLGVVLQNGRLMSG-SIFENIAggapLTLDEA-W----------EAARMAGLAEdiRAmpmgmHTVISEgggtLSGGQR 594
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 147 QRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVklglTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:TIGR03797 595 QRLLIARALVRKPRILLFDEATSALDNRTQAIVSESLERLKV----TRIVIAHRLSTIRN-ADRIYVLDAGRVVQQG 666
|
|
| ABC_cobalt_CbiO_domain2 |
cd03226 |
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of ... |
11-220 |
6.55e-34 |
|
Second domain of the ATP-binding cassette component of cobalt transport system; Domain II of the ABC component of a cobalt transport family found in bacteria, archaea, and eukaryota. The transition metal cobalt is an essential component of many enzymes and must be transported into cells in appropriate amounts when needed. The CbiMNQO family ABC transport system is involved in cobalt transport in association with the cobalamin (vitamin B12) biosynthetic pathways. Most cobalt (Cbi) transport systems possess a separate CbiN component, the cobalt-binding periplasmic protein, and they are encoded by the conserved gene cluster cbiMNQO. Both the CbiM and CbiQ proteins are integral cytoplasmic membrane proteins, and the CbiO protein has the linker peptide and the Walker A and B motifs commonly found in the ATPase components of the ABC-type transport systems.
Pssm-ID: 213193 [Multi-domain] Cd Length: 205 Bit Score: 123.91 E-value: 6.55e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDAvhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalPERELtlaRRQIGMIFQH 90
Cdd:cd03226 9 YKKGTEI---LDDLSLDLYAGEIIALTGKNGAGKTTLAKILAGLIKESSGSILLNGKPI---KAKER---RKSIGYVMQD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 FNL-LSSRTVFANIAFPLELAGWSKSQIRarvdELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:cd03226 80 VDYqLFTDSVREELLLGLKELDAGNEQAE----TVLKDLDLYALKERHPLSLSGGQKQRLAIAAALLSGKDLLIFDEPTS 155
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 754651031 170 ALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:cd03226 156 GLDYKNMERVGELIREL-AAQGKAVIVITHDYEFLAKVCDRVLLLANGAIV 205
|
|
| cbiO |
PRK13642 |
energy-coupling factor transporter ATPase; |
11-250 |
6.61e-34 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 184202 [Multi-domain] Cd Length: 277 Bit Score: 125.98 E-value: 6.61e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlpERELTLaRRQIGMIFQH 90
Cdd:PRK13642 14 YEKESD-VNQLNGVSFSITKGEWVSIIGQNGSGKSTTARLIDGLFEEFEGKVKIDGELLTA--ENVWNL-RRKIGMVFQN 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 -FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:PRK13642 90 pDNQFVGATVEDDVAFGMENQGIPREEMIKRVDEALLAVNMLDFKTREPARLSGGQKQRVAVAGIIALRPEIIILDESTS 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 170 ALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSNAKTQLardfihsTIHLEV 249
Cdd:PRK13642 170 MLDPTGRQEIMRVIHEIKEKYQLTVLSITHDLDEAAS-SDRILVMKAGEIIKEAAPSELFATSEDMV-------EIGLDV 241
|
.
gi 754651031 250 P 250
Cdd:PRK13642 242 P 242
|
|
| COG4586 |
COG4586 |
ABC-type uncharacterized transport system, ATPase component [General function prediction only]; ... |
1-302 |
1.10e-33 |
|
ABC-type uncharacterized transport system, ATPase component [General function prediction only];
Pssm-ID: 443643 [Multi-domain] Cd Length: 323 Bit Score: 126.74 E-value: 1.10e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVY--------GKGS---------DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVI 63
Cdd:COG4586 1 IIEVENLSKTYrvyekepgLKGAlkglfrreyREVEAVDDISFTIEPGEIVGFIGPNGAGKSTTIKMLTGILVPTSGEVR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 64 VDGQDlvalP-ERELTLARrQIGMIFQH-------------FNLLSsrtvfaniafplELAGWSKSQIRARVDELLALVG 129
Cdd:COG4586 81 VLGYV----PfKRRKEFAR-RIGVVFGQrsqlwwdlpaidsFRLLK------------AIYRIPDAEYKKRLDELVELLD 143
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 130 LE------ARahaypsELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDV 203
Cdd:COG4586 144 LGelldtpVR------QLSLGQRMRCELAAALLHRPKILFLDEPTIGLDVVSKEAIREFLKEYNRERGTTILLTSHDMDD 217
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 204 VKGICDDVAIISDGSLIEQGEVAWFFSN--AKTQLARDFIHSTIHLEVPQEyqdrlsAERVANSYPLVKLGFTGSTVDTP 281
Cdd:COG4586 218 IEALCDRVIVIDHGRIIYDGSLEELKERfgPYKTIVLELAEPVPPLELPRG------GEVIEREGNRVRLEVDPRESLAE 291
|
330 340
....*....|....*....|..
gi 754651031 282 LISEASRRFNI-DISILSADIE 302
Cdd:COG4586 292 VLARLLARYPVrDLTIEEPPIE 313
|
|
| ABCC_Protease_Secretion |
cd03246 |
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of ... |
2-217 |
1.16e-33 |
|
ATP-binding cassette domain of PrtD, subfamily C; This family represents the ABC component of the protease secretion system PrtD, a 60-kDa integral membrane protein sharing 37% identity with HlyB, the ABC component of the alpha-hemolysin secretion pathway, in the C-terminal domain. They export degradative enzymes by using a type I protein secretion system and lack an N-terminal signal peptide, but contain a C-terminal secretion signal. The Type I secretion apparatus is made up of three components, an ABC transporter, a membrane fusion protein (MFP), and an outer membrane protein (OMP). For the HlyA transporter complex, HlyB (ABC transporter) and HlyD (MFP) reside in the inner membrane of E. coli. The OMP component is TolC, which is thought to interact with the MFP to form a continuous channel across the periplasm from the cytoplasm to the exterior. HlyB belongs to the family of ABC transporters, which are ubiquitous, ATP-dependent transmembrane pumps or channels. The spectrum of transport substrates ranges from inorganic ions, nutrients such as amino acids, sugars, or peptides, hydrophobic drugs, to large polypeptides, such as HlyA.
Pssm-ID: 213213 [Multi-domain] Cd Length: 173 Bit Score: 122.32 E-value: 1.16e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:cd03246 1 LEVENVSFRYPGAEPPV--LRNVSFSIEPGESLAIIGPSGSGKSTLARLILGLLRPTSGRVRLDGADISQWDPNEL---G 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIafplelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPAPKV 161
Cdd:cd03246 76 DHVGYLPQDDELFSG-SIAENI-------------------------------------LSGGQRQRLGLARALYGNPRI 117
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKgICDDVAIISDG 217
Cdd:cd03246 118 LVLDEPNSHLDVEGERALNQAIAALKAA-GATRIVIAHRPETLA-SADRILVLEDG 171
|
|
| PRK11000 |
PRK11000 |
maltose/maltodextrin ABC transporter ATP-binding protein MalK; |
2-200 |
1.26e-33 |
|
maltose/maltodextrin ABC transporter ATP-binding protein MalK;
Pssm-ID: 182893 [Multi-domain] Cd Length: 369 Bit Score: 127.45 E-value: 1.26e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEreltlAR 81
Cdd:PRK11000 4 VTLRNVTKAYGD----VVISKDINLDIHEGEFVVFVGPSGCGKSTLLRMIAGLEDITSGDLFIGEKRMNDVPP-----AE 74
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:PRK11000 75 RGVGMVFQSYALYPHLSVAENMSFGLKLAGAKKEEINQRVNQVAEVLQLAHLLDRKPKALSGGQRQRVAIGRTLVAEPSV 154
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 754651031 162 LLCDEATSALDP----QTTRSILSLLKeinvKLGLTILLITHE 200
Cdd:PRK11000 155 FLLDEPLSNLDAalrvQMRIEISRLHK----RLGRTMIYVTHD 193
|
|
| hmuV |
PRK13548 |
hemin importer ATP-binding subunit; Provisional |
21-223 |
2.52e-33 |
|
hemin importer ATP-binding subunit; Provisional
Pssm-ID: 237422 [Multi-domain] Cd Length: 258 Bit Score: 124.11 E-value: 2.52e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRcvnLLE---RPTEGQVIVDGQDLVALPERELtlARRqIGMIFQHfnllssr 97
Cdd:PRK13548 18 LDDVSLTLRPGEVVAILGPNGAGKSTLLR---ALSgelSPDSGEVRLNGRPLADWSPAEL--ARR-RAVLPQH------- 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 tvfANIAFPLE--------LAGWSKSQIRAR--VDELLALVGLEARAH-AYPsELSGGQKQRVAIARALA------PAPK 160
Cdd:PRK13548 85 ---SSLSFPFTveevvamgRAPHGLSRAEDDalVAAALAQVDLAHLAGrDYP-QLSGGEQQRVQLARVLAqlwepdGPPR 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK13548 161 WLLLDEPTSALDLAHQHHVLRLARQLAHERGLAVIVVLHDLNLAARYADRIVLLHQGRLVADG 223
|
|
| oppD |
PRK09473 |
oligopeptide transporter ATP-binding component; Provisional |
18-225 |
3.90e-33 |
|
oligopeptide transporter ATP-binding component; Provisional
Pssm-ID: 181888 [Multi-domain] Cd Length: 330 Bit Score: 125.22 E-value: 3.90e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKS-TLIRCVNLLERP--TEGQVIVDGQDLVALPERELTLAR-RQIGMIFQhfNL 93
Cdd:PRK09473 29 VTAVNDLNFSLRAGETLGIVGESGSGKSqTAFALMGLLAANgrIGGSATFNGREILNLPEKELNKLRaEQISMIFQ--DP 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSRTVFANIAFPL-EL----AGWSKSQIRARVDELLALVGL-EARAH--AYPSELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:PRK09473 107 MTSLNPYMRVGEQLmEVlmlhKGMSKAEAFEESVRMLDAVKMpEARKRmkMYPHEFSGGMRQRVMIAMALLCRPKLLIAD 186
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 166 EATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:PRK09473 187 EPTTALDVTVQAQIMTLLNELKREFNTAIIMITHDLGVVAGICDKVLVMYAGRTMEYGNA 246
|
|
| met_CoM_red_A2 |
TIGR03269 |
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in ... |
2-224 |
4.79e-33 |
|
methyl coenzyme M reductase system, component A2; The enzyme that catalyzes the final step in methanogenesis, methyl coenzyme M reductase, contains alpha, beta, and gamma chains. In older literature, the complex of alpha, beta, and gamma chains was termed component C, while this single chain protein was termed methyl coenzyme M reductase system component A2. [Energy metabolism, Methanogenesis]
Pssm-ID: 132313 [Multi-domain] Cd Length: 520 Bit Score: 128.38 E-value: 4.79e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYgkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLE--RPTEGQVIV--------------- 64
Cdd:TIGR03269 1 IEVKNLTKKF----DGKEVLKNISFTIEEGEVLGILGRSGAGKSVLMHVLRGMDqyEPTSGRIIYhvalcekcgyverps 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 65 -DGQ--------------DLVALPERELTLARRQIGMIFQH-FNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALV 128
Cdd:TIGR03269 77 kVGEpcpvcggtlepeevDFWNLSDKLRRRIRKRIAIMLQRtFALYGDDTVLDNVLEALEEIGYEGKEAVGRAVDLIEMV 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 129 GLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGIC 208
Cdd:TIGR03269 157 QLSHRITHIARDLSGGEKQRVVLARQLAKEPFLFLADEPTGTLDPQTAKLVHNALEEAVKASGISMVLTSHWPEVIEDLS 236
|
250
....*....|....*.
gi 754651031 209 DDVAIISDGSLIEQGE 224
Cdd:TIGR03269 237 DKAIWLENGEIKEEGT 252
|
|
| ABCC_Glucan_exporter_like |
cd03254 |
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan ... |
2-223 |
9.49e-33 |
|
ATP-binding cassette domain of glucan transporter and related proteins, subfamily C; Glucan exporter ATP-binding protein. In A. tumefaciens cyclic beta-1, 2-glucan must be transported into the periplasmic space to exert its action as a virulence factor. This subfamily belongs to the MRP-like family and is involved in drug, peptide, and lipid export. The MRP-like family, similar to all ABC proteins, have a common four-domain core structure constituted by two membrane-spanning domains each composed of six transmembrane (TM) helices and two nucleotide-binding domains (NBD). ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213221 [Multi-domain] Cd Length: 229 Bit Score: 121.56 E-value: 9.49e-33
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLER---PTEGQVIVDGQDLVALPERELt 78
Cdd:cd03254 3 IEFENVNFSYDEK---KPVLKDINFSIKPGETVAIVGPTGAGKTTLI---NLLMRfydPQKGQILIDGIDIRDISRKSL- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 laRRQIGMIFQHfNLLSSRTVFANIAFPLELAGwsksqiRARVDELLALVG-------LEARAHAYPSE----LSGGQKQ 147
Cdd:cd03254 76 --RSMIGVVLQD-TFLFSGTIMENIRLGRPNAT------DEEVIEAAKEAGahdfimkLPNGYDTVLGEnggnLSQGERQ 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 148 RVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03254 147 LLAIARAMLRDPKILILDEATSNIDTETEKLIQEALEKLMK--GRTSIIIAHRLSTIKN-ADKILVLDDGKIIEEG 219
|
|
| ABC_NatA_like |
cd03267 |
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; ... |
18-223 |
1.47e-32 |
|
ATP-binding cassette domain of an uncharacterized transporter similar in sequence to NatA; NatA is the ATPase component of a bacterial ABC-type Na+ transport system called NatAB, which catalyzes ATP-dependent electrogenic Na+ extrusion without mechanically coupled to proton or K+ uptake. NatB possess six putative membrane spanning regions at its C-terminus. In B. subtilis, NatAB is inducible by agents such as ethanol and protonophores, which lower the proton-motive force across the membrane. The closest sequence similarity to NatA is exhibited by DrrA of the two-component daunorubicin- and doxorubicin-efflux system. Hence, the functional NatAB is presumably assembled with two copies of the single ATP-binding protein and the single integral membrane protein.
Pssm-ID: 213234 [Multi-domain] Cd Length: 236 Bit Score: 121.29 E-value: 1.47e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvaLPERELTLARRQIGMIF-QHFNL--- 93
Cdd:cd03267 34 VEALKGISFTIEKGEIVGFIGPNGAGKTTTLKILSGLLQPTSGEVRVAGL----VPWKRRKKFLRRIGVVFgQKTQLwwd 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 94 LSSRTVFANIAfplELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:cd03267 110 LPVIDSFYLLA---AIYDLPPARFKKRLDELSELLDLEELLDTPVRQLSLGQRMRAEIAAALLHEPEILFLDEPTIGLDV 186
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 754651031 174 QTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03267 187 VAQENIRNFLKEYNRERGTTVLLTSHYMKDIEALARRVLVIDKGRLLYDG 236
|
|
| nikD |
PRK10418 |
nickel transporter ATP-binding protein NikD; Provisional |
22-247 |
1.50e-32 |
|
nickel transporter ATP-binding protein NikD; Provisional
Pssm-ID: 236688 [Multi-domain] Cd Length: 254 Bit Score: 121.73 E-value: 1.50e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 22 RDVSLHVPQGKIFGVIGASGAGKStlIRCVNLLE------RPTEGQVIVDGQDLVALperelTLARRQIGMIFQH----F 91
Cdd:PRK10418 20 HGVSLTLQRGRVLALVGGSGSGKS--LTCAAALGilpagvRQTAGRVLLDGKPVAPC-----ALRGRKIATIMQNprsaF 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 NLLssRTVFANIAFPLELAGwsKSQIRARVDELLALVGLEARA---HAYPSELSGGQKQRVAIARAL-APAPkVLLCDEA 167
Cdd:PRK10418 93 NPL--HTMHTHARETCLALG--KPADDATLTAALEAVGLENAArvlKLYPFEMSGGMLQRMMIALALlCEAP-FIIADEP 167
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 168 TSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHStiHL 247
Cdd:PRK10418 168 TTDLDVVAQARILDLLESIVQKRALGMLLVTHDMGVVARLADDVAVMSHGRIVEQGDVETLFNAPKHAVTRSLVSA--HL 245
|
|
| COG4559 |
COG4559 |
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism]; |
21-226 |
1.98e-32 |
|
ABC-type hemin transport system, ATPase component [Inorganic ion transport and metabolism];
Pssm-ID: 443620 [Multi-domain] Cd Length: 258 Bit Score: 121.38 E-value: 1.98e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlARRqigmifqhfnllssRTVF 100
Cdd:COG4559 17 LDDVSLTLRPGELTAIIGPNGAGKSTLLKLLTGELTPSSGEVRLNGRPLAAWSPWEL--ARR--------------RAVL 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ---ANIAFPLE--------LAGW--SKSQIRARVDELLALVGLEARAH-AYPsELSGGQKQRVAIARALA-------PAP 159
Cdd:COG4559 81 pqhSSLAFPFTveevvalgRAPHgsSAAQDRQIVREALALVGLAHLAGrSYQ-TLSGGEQQRVQLARVLAqlwepvdGGP 159
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG4559 160 RWLFLDEPTSALDLAHQHAVLRLARQL-ARRGGGVVAVLHDLNLAAQYADRILLLHQGRLVAQGTPE 225
|
|
| PRK13536 |
PRK13536 |
nodulation factor ABC transporter ATP-binding protein NodI; |
2-223 |
2.15e-32 |
|
nodulation factor ABC transporter ATP-binding protein NodI;
Pssm-ID: 237419 [Multi-domain] Cd Length: 340 Bit Score: 123.40 E-value: 2.15e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsDAVhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGqdlVALPERElTLAR 81
Cdd:PRK13536 42 IDLAGVSKSYG---DKA-VVNGLSFTVASGECFGLLGPNGAGKSTIARMILGMTSPDAGKITVLG---VPVPARA-RLAR 113
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:PRK13536 114 ARIGVVPQFDNLDLEFTVRENLLVFGRYFGMSTREIEAVIPSLLEFARLESKADARVSDLSGGMKRRLTLARALINDPQL 193
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK13536 194 LILDEPTTGLDPHARHLIWERLRSL-LARGKTILLTTHFMEEAERLCDRLCVLEAGRKIAEG 254
|
|
| cbiO |
PRK13641 |
energy-coupling factor transporter ATPase; |
2-233 |
2.30e-32 |
|
energy-coupling factor transporter ATPase;
Pssm-ID: 237456 [Multi-domain] Cd Length: 287 Bit Score: 122.25 E-value: 2.30e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSD-AVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVA-LPERELTL 79
Cdd:PRK13641 3 IKFENVDYIYSPGTPmEKKGLDNISFELEEGSFVALVGHTGSGKSTLMQHFNALLKPSSGTITIAGYHITPeTGNKNLKK 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQhF--NLLSSRTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAHAYPSELSGGQKQRVAIARAL 155
Cdd:PRK13641 83 LRKKVSLVFQ-FpeAQLFENTVLKDVEFgPKNF-GFSEDEAKEKALKWLKKVGLsEDLISKSPFELSGGQMRRVAIAGVM 160
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:PRK13641 161 AYEPEILCLDEPAAGLDPEGRKEMMQLFKDYQ-KAGHTVILVTHNMDDVAEYADDVLVLEHGKLIKHASPKEIFSDKE 237
|
|
| cbiO |
PRK13631 |
cobalt transporter ATP-binding subunit; Provisional |
1-250 |
2.36e-32 |
|
cobalt transporter ATP-binding subunit; Provisional
Pssm-ID: 237451 [Multi-domain] Cd Length: 320 Bit Score: 123.04 E-value: 2.36e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYG-KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQV----IVDGQDLVALPER 75
Cdd:PRK13631 21 ILRVKNLYCVFDeKQENELVALNNISYTFEKNKIYFIIGNSGSGKSTLVTHFNGLIKSKYGTIqvgdIYIGDKKNNHELI 100
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 76 ELTLA---------RRQIGMIFQ--HFNLLSSrTVFANIAF-PLELaGWSKSQIRARVDELLALVGL-EARAHAYPSELS 142
Cdd:PRK13631 101 TNPYSkkiknfkelRRRVSMVFQfpEYQLFKD-TIEKDIMFgPVAL-GVKKSEAKKLAKFYLNKMGLdDSYLERSPFGLS 178
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 143 GGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQ 222
Cdd:PRK13631 179 GGQKRRVAIAGILAIQPEILIFDEPTAGLDPKGEHEMMQLILDAK-ANNKTVFVITHTMEHVLEVADEVIVMDKGKILKT 257
|
250 260
....*....|....*....|....*...
gi 754651031 223 GEVAWFFSNaktqlaRDFIHSTiHLEVP 250
Cdd:PRK13631 258 GTPYEIFTD------QHIINST-SIQVP 278
|
|
| PRK09984 |
PRK09984 |
phosphonate ABC transporter ATP-binding protein; |
1-223 |
2.96e-32 |
|
phosphonate ABC transporter ATP-binding protein;
Pssm-ID: 182182 [Multi-domain] Cd Length: 262 Bit Score: 121.27 E-value: 2.96e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgSDAVHAlrdVSLHVPQGKIFGVIGASGAGKSTLIRCVNLL---ERPTEGQVIVDGQDLvalpEREL 77
Cdd:PRK09984 4 IIRVEKLAKTFNQ-HQALHA---VDLNIHHGEMVALLGPSGSGKSTLLRHLSGLitgDKSAGSHIELLGRTV----QREG 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 78 TLA------RRQIGMIFQHFNLLSSRTVFANI--------AFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSG 143
Cdd:PRK09984 76 RLArdirksRANTGYIFQQFNLVNRLSVLENVligalgstPFWRTCFSWFTREQKQRALQALTRVGMVHFAHQRVSTLSG 155
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 144 GQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK09984 156 GQQQRVAIARALMQQAKVILADEPIASLDPESARIVMDTLRDINQNDGITVVVTLHQVDYALRYCERIVALRQGHVFYDG 235
|
|
| ABCC_MRP_domain2 |
cd03244 |
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C ... |
2-223 |
4.39e-32 |
|
ATP-binding cassette domain 2 of multidrug resistance-associated protein; The ABC subfamily C is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resistance lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213211 [Multi-domain] Cd Length: 221 Bit Score: 119.52 E-value: 4.39e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:cd03244 3 IEFKNVSLRYRPNLPPV--LKNISFSIKPGEKVGIVGRTGSGKSSLLLALFRLVELSSGSILIDGVDISKIGLHDL---R 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIAfPLELAG----WS---KSQIRARVDELLAlvGLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:cd03244 78 SRISIIPQDPVLFSG-TIRSNLD-PFGEYSdeelWQaleRVGLKEFVESLPG--GLDTVVEEGGENLSVGQRQLLCLARA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEiNVKlGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03244 154 LLRKSKILVLDEATASVDPETDALIQKTIRE-AFK-DCTVLTIAHRLDTIID-SDRILVLDKGRVVEFD 219
|
|
| ugpC |
PRK11650 |
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC; |
1-172 |
5.68e-32 |
|
sn-glycerol-3-phosphate ABC transporter ATP-binding protein UgpC;
Pssm-ID: 236947 [Multi-domain] Cd Length: 356 Bit Score: 122.64 E-value: 5.68e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHalrDVSLHVPQGKiFGVI-GASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltl 79
Cdd:PRK11650 3 GLKLQAVRKSYDGKTQVIK---GIDLDVADGE-FIVLvGPSGCGKSTLLRMVAGLERITSGEIWIGGRVVNELEPAD--- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 arRQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK11650 76 --RDIAMVFQNYALYPHMSVRENMAYGLKIRGMPKAEIEERVAEAARILELEPLLDRKPRELSGGQRQRVAMGRAIVREP 153
|
170
....*....|...
gi 754651031 160 KVLLCDEATSALD 172
Cdd:PRK11650 154 AVFLFDEPLSNLD 166
|
|
| PRK11176 |
PRK11176 |
lipid A ABC transporter ATP-binding protein/permease MsbA; |
20-246 |
1.21e-31 |
|
lipid A ABC transporter ATP-binding protein/permease MsbA;
Pssm-ID: 183016 [Multi-domain] Cd Length: 582 Bit Score: 125.13 E-value: 1.21e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQHFNLL 94
Cdd:PRK11176 358 ALRNINFKIPAGKTVALVGRSGSGKSTI---ANLLTRfydIDEGEILLDGHDL-----RDYTLAslRNQVALVSQNVHLF 429
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSrTVFANIAFPLElAGWSKSQIRARVDELLALVGLEARAHAYPSE-------LSGGQKQRVAIARALAPAPKVLLCDEA 167
Cdd:PRK11176 430 ND-TIANNIAYART-EQYSREQIEEAARMAYAMDFINKMDNGLDTVigengvlLSGGQRQRIAIARALLRDSPILILDEA 507
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 168 TSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGevawffsNAKTQLARDFIHSTIH 246
Cdd:PRK11176 508 TSALDTESERAIQAALDEL--QKNRTSLVIAHRLSTIEK-ADEILVVEDGEIVERG-------THAELLAQNGVYAQLH 576
|
|
| TagH |
COG1134 |
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate ... |
1-226 |
1.30e-31 |
|
ABC-type polysaccharide/polyol phosphate transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440749 [Multi-domain] Cd Length: 245 Bit Score: 119.03 E-value: 1.30e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVY------------------GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQV 62
Cdd:COG1134 4 MIEVENVSKSYrlyhepsrslkelllrrrRTRREEFWALKDVSFEVERGESVGIIGRNGAGKSTLLKLIAGILEPTSGRV 83
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 63 IVDGQdLVALPEreltlarrqIGMIFQhfnllSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHA----YP 138
Cdd:COG1134 84 EVNGR-VSALLE---------LGAGFH-----PELTGRENIYLNGRLLGLSRKEIDEKFDEIVEFAELGDFIDQpvktYS 148
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 139 SelsgGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGS 218
Cdd:COG1134 149 S----GMRARLAFAVATAVDPDILLVDEVLAVGDAAFQKKCLARIREL-RESGRTVIFVSHSMGAVRRLCDRAIWLEKGR 223
|
....*...
gi 754651031 219 LIEQGEVA 226
Cdd:COG1134 224 LVMDGDPE 231
|
|
| galliderm_ABC |
TIGR03740 |
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 ... |
2-225 |
1.49e-31 |
|
gallidermin-class lantibiotic protection ABC transporter, ATP-binding subunit; Model TIGR03731 represents the family of all lantibiotics related to gallidermin, including epidermin, mutatin, and nisin. This protein family describes the ATP-binding subunit of a gallidermin/epidermin class lantibiotic protection transporter. It is largely restricted to gallidermin-family lantibiotic biosynthesis and export cassettes, but also occurs in orphan transporter cassettes in species that lack candidate lantibiotic precursor and synthetase genes.
Pssm-ID: 163452 [Multi-domain] Cd Length: 223 Bit Score: 118.27 E-value: 1.49e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValpERELtlar 81
Cdd:TIGR03740 1 LETKNLSKRFGKQ----TAVNNISLTVPKNSVYGLLGPNGAGKSTLLKMITGILRPTSGEIIFDGHPWT---RKDL---- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSRTVFANIAFPLELAGWSKSqiraRVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:TIGR03740 70 HKIGSLIESPPLYENLTARENLKVHTTLLGLPDS----RIDEVLNIVDLTNTGKKKAKQFSLGMKQRLGIAIALLNHPKL 145
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 162 LLCDEATSALDP---QTTRSILSLLKEinvkLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:TIGR03740 146 LILDEPTNGLDPigiQELRELIRSFPE----QGITVILSSHILSEVQQLADHIGIISEGVLGYQGKI 208
|
|
| 3a01208 |
TIGR00958 |
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other] |
21-223 |
3.91e-31 |
|
Conjugate Transporter-2 (CT2) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273363 [Multi-domain] Cd Length: 711 Bit Score: 124.06 E-value: 3.91e-31
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTlirCVNLLER---PTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHfNLLSSR 97
Cdd:TIGR00958 497 LKGLTFTLHPGEVVALVGPSGSGKST---VAALLQNlyqPTGGQVLLDGVPLVQYDHHYL---HRQVALVGQE-PVLFSG 569
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFPLElagwsksqiRARVDELLAlVGLEARAHAYPSE---------------LSGGQKQRVAIARALAPAPKVL 162
Cdd:TIGR00958 570 SVRENIAYGLT---------DTPDEEIMA-AAKAANAHDFIMEfpngydtevgekgsqLSGGQKQRIAIARALVRKPRVL 639
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 163 LCDEATSALDPQTTRsilsLLKEINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:TIGR00958 640 ILDEATSALDAECEQ----LLQESRSRASRTVLLIAHRLSTVER-ADQILVLKKGSVVEMG 695
|
|
| dppD |
PRK11022 |
dipeptide transporter ATP-binding subunit; Provisional |
1-230 |
4.87e-30 |
|
dipeptide transporter ATP-binding subunit; Provisional
Pssm-ID: 182906 [Multi-domain] Cd Length: 326 Bit Score: 116.76 E-value: 4.87e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKS-TLIRCVNLLERPteGQVIVD-----GQDLVALPE 74
Cdd:PRK11022 3 LLNVDKLSVHFGDESAPFRAVDRISYSVKQGEVVGIVGESGSGKSvSSLAIMGLIDYP--GRVMAEklefnGQDLQRISE 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 75 REltlaRRQI-----GMIFQH--FNLLSSRTVFANIAFPLEL-AGWSKSQIRARVDELLALVGL---EARAHAYPSELSG 143
Cdd:PRK11022 81 KE----RRNLvgaevAMIFQDpmTSLNPCYTVGFQIMEAIKVhQGGNKKTRRQRAIDLLNQVGIpdpASRLDVYPHQLSG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 144 GQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11022 157 GMSQRVMIAMAIACRPKLLIADEPTTALDVTIQAQIIELLLELQQKENMALVLITHDLALVAEAAHKIIVMYAGQVVETG 236
|
....*..
gi 754651031 224 EVAWFFS 230
Cdd:PRK11022 237 KAHDIFR 243
|
|
| fecE |
PRK11231 |
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE; |
1-223 |
5.34e-30 |
|
Fe(3+) dicitrate ABC transporter ATP-binding protein FecE;
Pssm-ID: 183044 [Multi-domain] Cd Length: 255 Bit Score: 115.11 E-value: 5.34e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTla 80
Cdd:PRK11231 2 TLRTENLTVGYGTKR----ILNDLSLSLPTGKITALIGPNGCGKSTLLKCFARLLTPQSGTVFLGDKPISMLSSRQLA-- 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rRQIGMIFQHFNLLSSRTVFANIAF---P-LELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:PRK11231 76 -RRLALLPQHHLTPEGITVRELVAYgrsPwLSLWGRLSAEDNARVNQAMEQTRINHLADRRLTDLSGGQRQRAFLAMVLA 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11231 155 QDTPVVLLDEPTTYLDINHQVELMRLMRELNTQ-GKTVVTVLHDLNQASRYCDHLVVLANGHVMAQG 220
|
|
| ABC_KpsT_Wzt |
cd03220 |
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC ... |
2-223 |
6.42e-30 |
|
ATP-binding cassette component of polysaccharide transport system; The KpsT/Wzt ABC transporter subfamily is involved in extracellular polysaccharide export. Among the variety of membrane-linked or extracellular polysaccharides excreted by bacteria, only capsular polysaccharides, lipopolysaccharides, and teichoic acids have been shown to be exported by ABC transporters. A typical system is made of a conserved integral membrane and an ABC. In addition to these proteins, capsular polysaccharide exporter systems require two 'accessory' proteins to perform their function: a periplasmic (E.coli) or a lipid-anchored outer membrane protein called OMA (Neisseria meningitidis and Haemophilus influenza) and a cytoplasmic membrane protein MPA2.
Pssm-ID: 213187 [Multi-domain] Cd Length: 224 Bit Score: 113.78 E-value: 6.42e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVY---GKGSDA---------------VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVI 63
Cdd:cd03220 1 IELENVSKSYptyKGGSSSlkklgilgrkgevgeFWALKDVSFEVPRGERIGLIGRNGAGKSTLLRLLAGIYPPDSGTVT 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 64 VDGQdLVALPEreltlarrqIGMIFQhfnllSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSG 143
Cdd:cd03220 81 VRGR-VSSLLG---------LGGGFN-----PELTGRENIYLNGRLLGLSRKEIDEKIDEIIEFSELGDFIDLPVKTYSS 145
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 144 GQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03220 146 GMKARLAFAIATALEPDILLIDEVLAVGDAAFQEKCQRRLREL-LKQGKTVILVSHDPSSIKRLCDRALVLEKGKIRFDG 224
|
|
| livG |
PRK11300 |
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional |
20-223 |
6.54e-30 |
|
leucine/isoleucine/valine transporter ATP-binding subunit; Provisional
Pssm-ID: 183080 [Multi-domain] Cd Length: 255 Bit Score: 114.70 E-value: 6.54e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlARRQIGMIFQHFNLLSSRTV 99
Cdd:PRK11300 20 AVNNVNLEVREQEIVSLIGPNGAGKTTVFNCLTGFYKPTGGTILLRGQHIEGLPGHQI--ARMGVVRTFQHVRLFREMTV 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FAN-------------IAFPLELAGWSKSQIRA--RVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLC 164
Cdd:PRK11300 98 IENllvaqhqqlktglFSGLLKTPAFRRAESEAldRAATWLERVGLLEHANRQAGNLAYGQQRRLEIARCMVTQPEILML 177
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 165 DEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11300 178 DEPAAGLNPKETKELDELIAELRNEHNVTVLLIEHDMKLVMGISDRIYVVNQGTPLANG 236
|
|
| PRK15134 |
PRK15134 |
microcin C ABC transporter ATP-binding protein YejF; Provisional |
23-279 |
1.24e-29 |
|
microcin C ABC transporter ATP-binding protein YejF; Provisional
Pssm-ID: 237917 [Multi-domain] Cd Length: 529 Bit Score: 118.65 E-value: 1.24e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKS-TLIRCVNLLERP----TEGQVIVDGQDLVALPERELTLAR-RQIGMIFQH--FNLL 94
Cdd:PRK15134 27 DVSLQIEAGETLALVGESGSGKSvTALSILRLLPSPpvvyPSGDIRFHGESLLHASEQTLRGVRgNKIAMIFQEpmVSLN 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANIAFPLEL-AGWSKSQIRARVDELLALVGLE---ARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSA 170
Cdd:PRK15134 107 PLHTLEKQLYEVLSLhRGMRREAARGEILNCLDRVGIRqaaKRLTDYPHQLSGGERQRVMIAMALLTRPELLIADEPTTA 186
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 171 LDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHSTIH---L 247
Cdd:PRK15134 187 LDVSVQAQILQLLRELQQELNMGLLFITHNLSIVRKLADRVAVMQNGRCVEQNRAATLFSAPTHPYTQKLLNSEPSgdpV 266
|
250 260 270
....*....|....*....|....*....|..
gi 754651031 248 EVPQEYQDRLSAERVANSYPlVKLGFTGSTVD 279
Cdd:PRK15134 267 PLPEPASPLLDVEQLQVAFP-IRKGILKRTVD 297
|
|
| cbiO |
PRK13638 |
energy-coupling factor ABC transporter ATP-binding protein; |
21-234 |
1.57e-29 |
|
energy-coupling factor ABC transporter ATP-binding protein;
Pssm-ID: 184198 [Multi-domain] Cd Length: 271 Bit Score: 114.33 E-value: 1.57e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvALPERELTLARRQIGMIFQHfnllSSRTVF 100
Cdd:PRK13638 17 LKGLNLDFSLSPVTGLVGANGCGKSTLFMNLSGLLRPQKGAVLWQGKPL-DYSKRGLLALRQQVATVFQD----PEQQIF 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 -----ANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:PRK13638 92 ytdidSDIAFSLRNLGVPEAEITRRVDEALTLVDAQHFRHQPIQCLSHGQKKRVAIAGALVLQARYLLLDEPTAGLDPAG 171
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 176 TRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKT 234
Cdd:PRK13638 172 RTQMIAIIRRI-VAQGNHVIISSHDIDLIYEISDAVYVLRQGQILTHGAPGEVFACTEA 229
|
|
| ABCC_bacteriocin_exporters |
cd03245 |
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic ... |
16-223 |
1.60e-29 |
|
ATP-binding cassette domain of bacteriocin exporters, subfamily C; Many non-lantibiotic bacteriocins of lactic acid bacteria are produced as precursors which have N-terminal leader peptides that share similarities in amino acid sequence and contain a conserved processing site of two glycine residues in positions -1 and -2. A dedicated ATP-binding cassette (ABC) transporter is responsible for the proteolytic cleavage of the leader peptides and subsequent translocation of the bacteriocins across the cytoplasmic membrane.
Pssm-ID: 213212 [Multi-domain] Cd Length: 220 Bit Score: 112.68 E-value: 1.60e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 16 DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLS 95
Cdd:cd03245 15 QEIPALDNVSLTIRAGEKVAIIGRVGSGKSTLLKLLAGLYKPTSGSVLLDGTDIRQLDPADL---RRNIGYVPQDVTLFY 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SrTVFANIAF------------PLELAGwsksqirarVDELLAL--VGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03245 92 G-TLRDNITLgapladderilrAAELAG---------VTDFVNKhpNGLDLQIGERGRGLSGGQRQAVALARALLNDPPI 161
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEinVKLGLTILLITHEMDVVKgICDDVAIISDGSLIEQG 223
Cdd:cd03245 162 LLLDEPTSAMDMNSEERLKERLRQ--LLGDKTLIIITHRPSLLD-LVDRIIVMDSGRIVADG 220
|
|
| SapD |
COG4170 |
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms]; |
18-224 |
1.99e-29 |
|
ABC-type antimicrobial peptide export system, ATPase component SapD [Defense mechanisms];
Pssm-ID: 443330 [Multi-domain] Cd Length: 331 Bit Score: 115.39 E-value: 1.99e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRC-VNLLE---RPTEGQVIVDGQDLVALPEREL-TLARRQIGMIFQHFN 92
Cdd:COG4170 20 VKAVDRVSLTLNEGEIRGLVGESGSGKSLIAKAiCGITKdnwHVTADRFRWNGIDLLKLSPRERrKIIGREIAMIFQEPS 99
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 --LLSSRTVFANIAFPL---ELAG--WSKSQIRA-RVDELLALVGLeaRAH-----AYPSELSGGQKQRVAIARALAPAP 159
Cdd:COG4170 100 scLDPSAKIGDQLIEAIpswTFKGkwWQRFKWRKkRAIELLHRVGI--KDHkdimnSYPHELTEGECQKVMIAMAIANQP 177
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:COG4170 178 RLLIADEPTNAMESTTQAQIFRLLARLNQLQGTSILLISHDLESISQWADTITVLYCGQTVESGP 242
|
|
| phnK |
PRK11701 |
phosphonate C-P lyase system protein PhnK; Provisional |
1-223 |
2.93e-29 |
|
phosphonate C-P lyase system protein PhnK; Provisional
Pssm-ID: 183280 [Multi-domain] Cd Length: 258 Bit Score: 113.10 E-value: 2.93e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ-----DLVALPER 75
Cdd:PRK11701 6 LLSVRGLTKLYG----PRKGCRDVSFDLYPGEVLGIVGESGSGKTTLLNALSARLAPDAGEVHYRMRdgqlrDLYALSEA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 76 EL-TLARRQIGMIFQH--FNLLSSRTVFANIAFPLELAGWSK-SQIRARVDELLALVGLEA-RAHAYPSELSGGQKQRVA 150
Cdd:PRK11701 82 ERrRLLRTEWGFVHQHprDGLRMQVSAGGNIGERLMAVGARHyGDIRATAGDWLERVEIDAaRIDDLPTTFSGGMQQRLQ 161
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 151 IARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11701 162 IARNLVTHPRLVFMDEPTGGLDVSVQARLLDLLRGLVRELGLAVVIVTHDLAVARLLAHRLLVMKQGRVVESG 234
|
|
| ABCG_EPDR |
cd03213 |
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette ... |
21-223 |
3.77e-29 |
|
Eye pigment and drug resistance transporter subfamily G of the ATP-binding cassette superfamily; ABCG transporters are involved in eye pigment (EP) precursor transport, regulation of lipid-trafficking mechanisms, and pleiotropic drug resistance (DR). DR is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. Compared to other members of the ABC transporter subfamilies, the ABCG transporter family is composed of proteins that have an ATP-binding cassette domain at the N-terminus and a TM (transmembrane) domain at the C-terminus.
Pssm-ID: 213180 [Multi-domain] Cd Length: 194 Bit Score: 111.10 E-value: 3.77e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVN--LLERPTEGQVIVDGQDlvaLPERELtlaRRQIGMIFQHFNLLSSRT 98
Cdd:cd03213 25 LKNVSGKAKPGELTAIMGPSGAGKSTLLNALAgrRTGLGVSGEVLINGRP---LDKRSF---RKIIGYVPQDDILHPTLT 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPLELAGwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:cd03213 99 VRETLMFAAKLRG-----------------------------LSGGERKRVSIALELVSNPSLLFLDEPTSGLDSSSALQ 149
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 754651031 179 ILSLLKEInVKLGLTILLITHE-MDVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03213 150 VMSLLRRL-ADTGRTIICSIHQpSSEIFELFDKLLLLSQGRVIYFG 194
|
|
| PRK15112 |
PRK15112 |
peptide ABC transporter ATP-binding protein SapF; |
18-243 |
7.22e-29 |
|
peptide ABC transporter ATP-binding protein SapF;
Pssm-ID: 185067 [Multi-domain] Cd Length: 267 Bit Score: 112.19 E-value: 7.22e-29
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlpeRELTLARRQIGMIFQH-FNLLSS 96
Cdd:PRK15112 26 VEAVKPLSFTLREGQTLAIIGENGSGKSTLAKMLAGMIEPTSGELLIDDHPLHF---GDYSYRSQRIRMIFQDpSTSLNP 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIA-FPLEL-AGWSKSQIRARVDELLALVGLEA-RAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:PRK15112 103 RQRISQILdFPLRLnTDLEPEQREKQIIETLRQVGLLPdHASYYPHMLAPGQKQRLGLARALILRPKVIIADEALASLDM 182
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 174 QTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLARDFIHS 243
Cdd:PRK15112 183 SMRSQLINLMLELQEKQGISYIYVTQHLGMMKHISDQVLVMHQGEVVERGSTADVLASPLHELTKRLIAG 252
|
|
| CydD |
TIGR02857 |
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family ... |
2-199 |
1.08e-28 |
|
thiol reductant ABC exporter, CydD subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex. Unfortunately, the gene symbol nomenclature adopted based on this operon in B. subtilis assigns cydC to the third gene in the operon where this gene is actually homologous to the E. coli cydD gene. We have chosen to name all homologs in this family in accordance with the precedence of publication of the E. coli name, CydD
Pssm-ID: 274323 [Multi-domain] Cd Length: 529 Bit Score: 116.23 E-value: 1.08e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:TIGR02857 322 LEFSGVSVAYP---GRRPALRPVSFTVPPGERVALVGPSGAGKSTLLNLLLGFVDPTEGSIAVNGVPLADADADSW---R 395
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIAF------PLELAGwskSQIRARVDELLALV--GLEARAHAYPSELSGGQKQRVAIAR 153
Cdd:TIGR02857 396 DQIAWVPQHPFLFAG-TIAENIRLarpdasDAEIRE---ALERAGLDEFVAALpqGLDTPIGEGGAGLSGGQAQRLALAR 471
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 754651031 154 ALAPAPKVLLCDEATSALDPQTTRSILSLLKEInvKLGLTILLITH 199
Cdd:TIGR02857 472 AFLRDAPLLLLDEPTAHLDAETEAEVLEALRAL--AQGRTVLLVTH 515
|
|
| PRK10575 |
PRK10575 |
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC; |
21-224 |
1.11e-28 |
|
Fe3+-hydroxamate ABC transporter ATP-binding protein FhuC;
Pssm-ID: 182561 [Multi-domain] Cd Length: 265 Bit Score: 111.80 E-value: 1.11e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTlarRQIGMIFQHFNLLSSRTVF 100
Cdd:PRK10575 27 LHPLSLTFPAGKVTGLIGHNGSGKSTLLKMLGRHQPPSEGEILLDAQPLESWSSKAFA---RKVAYLPQQLPAAEGMTVR 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIA---FPLELA-GWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTT 176
Cdd:PRK10575 104 ELVAigrYPWHGAlGRFGAADREKVEEAISLVGLKPLAHRLVDSLSGGERQRAWIAMLVAQDSRCLLLDEPTSALDIAHQ 183
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 754651031 177 RSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:PRK10575 184 VDVLALVHRLSQERGLTVIAVLHDINMAARYCDYLVALRGGEMIAQGT 231
|
|
| ABCG_White |
cd03234 |
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ... |
21-223 |
2.03e-28 |
|
White pigment protein homolog of ABCG transporter subfamily; The White subfamily represents ABC transporters homologous to the Drosophila white gene, which acts as a dimeric importer for eye pigment precursors. The eye pigmentation of Drosophila is developed from the synthesis and deposition in the cells of red pigments, which are synthesized from guanine, and brown pigments, which are synthesized from tryptophan. The pigment precursors are encoded by the white, brown, and scarlet genes, respectively. Evidence from genetic and biochemical studies suggest that the White and Brown proteins function as heterodimers to import guanine, while the White and Scarlet proteins function to import tryptophan. However, a recent study also suggests that White may be involved in the transport of a metabolite, such as 3-hydroxykynurenine, across intracellular membranes. Mammalian ABC transporters belonging to the White subfamily (ABCG1, ABCG5, and ABCG8) have been shown to be involved in the regulation of lipid-trafficking mechanisms in macrophages, hepatocytes, and intestinal mucosa cells. ABCG1 (ABC8), the human homolog of the Drosophila white gene is induced in monocyte-derived macrophages during cholesterol influx mediated by acetylated low-density lipoprotein. It is possible that human ABCG1 forms heterodimers with several heterologous partners.
Pssm-ID: 213201 [Multi-domain] Cd Length: 226 Bit Score: 110.05 E-value: 2.03e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLERP--TEGQVIVDGQdlvalpERELTLARRQIGMIFQHFNLLSSR 97
Cdd:cd03234 23 LNDVSLHVESGQVMAILGSSGSGKTTLLDAIsGRVEGGgtTSGQILFNGQ------PRKPDQFQKCVAYVRQDDILLPGL 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFPLELAG---WSKSQIRARV-DELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:cd03234 97 TVRETLTYTAILRLprkSSDAIRKKRVeDVLLRDLALTRIGGNLVKGISGGERRRVSIAVQLLWDPKVLILDEPTSGLDS 176
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 174 QTTRSILSLLKEINVKlGLTILLITHE--MDVVKgICDDVAIISDGSLIEQG 223
Cdd:cd03234 177 FTALNLVSTLSQLARR-NRIVILTIHQprSDLFR-LFDRILLLSSGEIVYSG 226
|
|
| modC |
PRK11144 |
molybdenum ABC transporter ATP-binding protein ModC; |
23-223 |
2.07e-28 |
|
molybdenum ABC transporter ATP-binding protein ModC;
Pssm-ID: 182993 [Multi-domain] Cd Length: 352 Bit Score: 113.05 E-value: 2.07e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALpERELTLA--RRQIGMIFQHFNLLSSRTVF 100
Cdd:PRK11144 16 TVNLTLPAQGITAIFGRSGAGKTSLINAISGLTRPQKGRIVLNGRVLFDA-EKGICLPpeKRRIGYVFQDARLFPHYKVR 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFplelaGWSKSQiRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSIL 180
Cdd:PRK11144 95 GNLRY-----GMAKSM-VAQFDKIVALLGIEPLLDRYPGSLSGGEKQRVAIGRALLTAPELLLMDEPLASLDLPRKRELL 168
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 754651031 181 SLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK11144 169 PYLERLAREINIPILYVSHSLDEILRLADRVVVLEQGKVKAFG 211
|
|
| ABCC_TAP |
cd03248 |
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; ... |
21-205 |
3.96e-28 |
|
ATP-binding cassette domain of the Transporter Associated with Antigen Processing, subfamily C; TAP (Transporter Associated with Antigen Processing) is essential for peptide delivery from the cytosol into the lumen of the endoplasmic reticulum (ER), where these peptides are loaded on major histocompatibility complex (MHC) I molecules. Loaded MHC I leave the ER and display their antigenic cargo on the cell surface to cytotoxic T cells. Subsequently, virus-infected or malignantly transformed cells can be eliminated. TAP belongs to the large family of ATP-binding cassette (ABC) transporters, which translocate a vast variety of solutes across membranes.
Pssm-ID: 213215 [Multi-domain] Cd Length: 226 Bit Score: 109.10 E-value: 3.96e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTlirCVNLLER---PTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHfNLLSSR 97
Cdd:cd03248 30 LQDVSFTLHPGEVTALVGPSGSGKST---VVALLENfyqPQGGQVLLDGKPISQYEHKYL---HSKVSLVGQE-PVLFAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFplELAGWSKSQIRARVDELLALVGLEARAHAYPSE-------LSGGQKQRVAIARALAPAPKVLLCDEATSA 170
Cdd:cd03248 103 SLQDNIAY--GLQSCSFECVKEAAQKAHAHSFISELASGYDTEvgekgsqLSGGQKQRVAIARALIRNPQVLILDEATSA 180
|
170 180 190
....*....|....*....|....*....|....*
gi 754651031 171 LDPQTTRSILSLLKEINVKlgLTILLITHEMDVVK 205
Cdd:cd03248 181 LDAESEQQVQQALYDWPER--RTVLVIAHRLSTVE 213
|
|
| ModF |
COG1119 |
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA ... |
1-226 |
5.27e-28 |
|
ABC-type molybdenum transport system, ATPase component ModF/photorepair protein PhrA [Inorganic ion transport and metabolism];
Pssm-ID: 440736 [Multi-domain] Cd Length: 250 Bit Score: 109.40 E-value: 5.27e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVI-VDGQDLVALPERELtl 79
Cdd:COG1119 3 LLELRNVTVRRGG----KTILDDISWTVKPGEHWAILGPNGAGKSTLLSLITGDLPPTYGNDVrLFGERRGGEDVWEL-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 aRRQIGMI--FQHFNLLSSRTV--------FANIAFPLELagwSKSQiRARVDELLALVGLEARAHAYPSELSGGQKQRV 149
Cdd:COG1119 77 -RKRIGLVspALQLRFPRDETVldvvlsgfFDSIGLYREP---TDEQ-RERARELLELLGLAHLADRPFGTLSQGEQRRV 151
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEM-DVVKGIcDDVAIISDGSLIEQGEVA 226
Cdd:COG1119 152 LIARALVKDPELLILDEPTAGLDLGARELLLALLDKLAAEGAPTLVLVTHHVeEIPPGI-THVLLLKDGRVVAAGPKE 228
|
|
| btuD |
PRK09536 |
corrinoid ABC transporter ATPase; Reviewed |
1-223 |
6.23e-28 |
|
corrinoid ABC transporter ATPase; Reviewed
Pssm-ID: 236554 [Multi-domain] Cd Length: 402 Bit Score: 112.63 E-value: 6.23e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTla 80
Cdd:PRK09536 3 MIDVSDLSVEFG----DTTVLDGVDLSVREGSLVGLVGPNGAGKTTLLRAINGTLTPTAGTVLVAGDDVEALSARAAS-- 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rRQIGMIFQHFNL---LSSRTVFANIAFP--LELAGWSKSQIRArVDELLALVGLEARAHAYPSELSGGQKQRVAIARAL 155
Cdd:PRK09536 77 -RRVASVPQDTSLsfeFDVRQVVEMGRTPhrSRFDTWTETDRAA-VERAMERTGVAQFADRPVTSLSGGERQRVLLARAL 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK09536 155 AQATPVLLLDEPTASLDINHQVRTLELVRRL-VDDGKTAVAAIHDLDLAARYCDELVLLADGRVRAAG 221
|
|
| ABC_Carb_Monos_II |
cd03215 |
Second domain of the ATP-binding cassette component of monosaccharide transport system; This ... |
20-219 |
8.04e-28 |
|
Second domain of the ATP-binding cassette component of monosaccharide transport system; This family represents domain II of the carbohydrate uptake proteins that transport only monosaccharides (Monos). The Carb_Monos family is involved in the uptake of monosaccharides, such as pentoses (such as xylose, arabinose, and ribose) and hexoses (such as xylose, arabinose, and ribose), that cannot be broken down to simple sugars by hydrolysis. In members of Carb_Monos family the single hydrophobic gene product forms a homodimer, while the ABC protein represents a fusion of two nucleotide-binding domains. However, it is assumed that two copies of the ABC domains are present in the assembled transporter.
Pssm-ID: 213182 [Multi-domain] Cd Length: 182 Bit Score: 107.13 E-value: 8.04e-28
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlaRRQIGMIF-----QHFNLL 94
Cdd:cd03215 15 AVRDVSFEVRAGEIVGIAGLVGNGQTELAEALFGLRPPASGEITLDGKPVTRRSPRD----AIRAGIAYvpedrKREGLV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANIAFPlelagwsksqirarvdellalvglearahaypSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQ 174
Cdd:cd03215 91 LDLSVAENIALS--------------------------------SLLSGGNQQKVVLARWLARDPRVLILDEPTRGVDVG 138
|
170 180 190 200
....*....|....*....|....*....|....*....|....*
gi 754651031 175 TTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:cd03215 139 AKAEIYRLIRELADA-GKAVLLISSELDELLGLCDRILVMYEGRI 182
|
|
| PRK10247 |
PRK10247 |
putative ABC transporter ATP-binding protein YbbL; Provisional |
7-211 |
3.97e-27 |
|
putative ABC transporter ATP-binding protein YbbL; Provisional
Pssm-ID: 182331 [Multi-domain] Cd Length: 225 Bit Score: 106.72 E-value: 3.97e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 7 LNKVyGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAL-PEReltlARRQIG 85
Cdd:PRK10247 10 LQNV-GYLAGDAKILNNISFSLRAGEFKLITGPSGCGKSTLLKIVASLISPTSGTLLFEGEDISTLkPEI----YRQQVS 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 86 MIFQHFNLLSSrTVFANIAFPLELAGwSKSQIRARVDEL----LALVGLEARAhaypSELSGGQKQRVAIARALAPAPKV 161
Cdd:PRK10247 85 YCAQTPTLFGD-TVYDNLIFPWQIRN-QQPDPAIFLDDLerfaLPDTILTKNI----AELSGGEKQRISLIRNLQFMPKV 158
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGiCDDV 211
Cdd:PRK10247 159 LLLDEITSALDESNKHNVNEIIHRYVREQNIAVLWVTHDKDEINH-ADKV 207
|
|
| PRK13657 |
PRK13657 |
glucan ABC transporter ATP-binding protein/ permease; |
20-223 |
7.30e-27 |
|
glucan ABC transporter ATP-binding protein/ permease;
Pssm-ID: 184214 [Multi-domain] Cd Length: 588 Bit Score: 111.21 E-value: 7.30e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLER---PTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQHfNLL 94
Cdd:PRK13657 350 GVEDVSFEAKPGQTVAIVGPTGAGKSTLI---NLLQRvfdPQSGRILIDGTDI-----RTVTRAslRRNIAVVFQD-AGL 420
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 95 SSRTVFANI------AFPLELAGWSKsqiRARVDELLA--LVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDE 166
Cdd:PRK13657 421 FNRSIEDNIrvgrpdATDEEMRAAAE---RAQAHDFIErkPDGYDTVVGERGRQLSGGERQRLAIARALLKDPPILILDE 497
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 167 ATSALDPQTTRSILSLLKEinVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:PRK13657 498 ATSALDVETEAKVKAALDE--LMKGRTTFIIAHRLSTVRN-ADRILVFDNGRVVESG 551
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
1-226 |
1.81e-26 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 109.49 E-value: 1.81e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERelTLA 80
Cdd:PRK09700 5 YISMAGIGKSFG----PVHALKSVNLTVYPGEIHALLGENGAGKSTLMKVLSGIHEPTKGTITINNINYNKLDHK--LAA 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANI---------AFPLELAGWSKSQIRARVdeLLALVGLEARAHAYPSELSGGQKQRVAI 151
Cdd:PRK09700 79 QLGIGIIYQELSVIDELTVLENLyigrhltkkVCGVNIIDWREMRVRAAM--MLLRVGLKVDLDEKVANLSISHKQMLEI 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 152 ARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:PRK09700 157 AKTLMLDAKVIIMDEPTSSLTNKEVDYLFLIMNQLR-KEGTAIVYISHKLAEIRRICDRYTVMKDGSSVCSGMVS 230
|
|
| PRK10895 |
PRK10895 |
lipopolysaccharide ABC transporter ATP-binding protein; Provisional |
7-223 |
3.68e-26 |
|
lipopolysaccharide ABC transporter ATP-binding protein; Provisional
Pssm-ID: 182817 [Multi-domain] Cd Length: 241 Bit Score: 104.59 E-value: 3.68e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 7 LNKVYgKGSDAVHalrDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlARRQIGM 86
Cdd:PRK10895 9 LAKAY-KGRRVVE---DVSLTVNSGEIVGLLGPNGAGKTTTFYMVVGIVPRDAGNIIIDDEDISLLPLHAR--ARRGIGY 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 87 IFQHFNLLSSRTVFANIAFPLEL-AGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:PRK10895 83 LPQEASIFRRLSVYDNLMAVLQIrDDLSAEQREDRANELMEEFHIEHLRDSMGQSLSGGERRRVEIARALAANPKFILLD 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 166 EATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK10895 163 EPFAGVDPISVIDIKRIIEHLR-DSGLGVLITDHNVRETLAVCERAYIVSQGHLIAHG 219
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
30-223 |
6.13e-26 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 109.33 E-value: 6.13e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 30 QGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalpERELTLARRQIGMIFQHFNLLSSRTVFANIAFPLEL 109
Cdd:TIGR01257 955 ENQITAFLGHNGAGKTTTLSILTGLLPPTSGTVLVGGKDI----ETNLDAVRQSLGMCPQHNILFHHLTVAEHILFYAQL 1030
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 110 AGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLkeINVK 189
Cdd:TIGR01257 1031 KGRSWEEAQLEMEAMLEDTGLHHKRNEEAQDLSGGMQRKLSVAIAFVGDAKVVVLDEPTSGVDPYSRRSIWDLL--LKYR 1108
|
170 180 190
....*....|....*....|....*....|....
gi 754651031 190 LGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:TIGR01257 1109 SGRTIIMSTHHMDEADLLGDRIAIISQGRLYCSG 1142
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
12-221 |
7.90e-26 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 107.69 E-value: 7.90e-26
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 12 GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLArrQIGMIFQHF 91
Cdd:PRK11288 11 GKTFPGVKALDDISFDCRAGQVHALMGENGAGKSTLLKILSGNYQPDAGSILIDGQEMRFASTTAALAA--GVAIIYQEL 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 NLLSSRTVFANI---AFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEAT 168
Cdd:PRK11288 89 HLVPEMTVAENLylgQLPHKGGIVNRRLLNYEAREQLEHLGVDIDPDTPLKYLSIGQRQMVEIAKALARNARVIAFDEPT 168
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 754651031 169 SALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:PRK11288 169 SSLSAREIEQLFRVIRELRAE-GRVILYVSHRMEEIFALCDAITVFKDGRYVA 220
|
|
| PRK14271 |
PRK14271 |
phosphate ABC transporter ATP-binding protein; Provisional |
21-233 |
1.07e-25 |
|
phosphate ABC transporter ATP-binding protein; Provisional
Pssm-ID: 172759 [Multi-domain] Cd Length: 276 Bit Score: 104.02 E-value: 1.07e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEG-----QVIVDGQDLVALpeRELTLARRQIGMIFQH---FN 92
Cdd:PRK14271 37 LDQVSMGFPARAVTSLMGPTGSGKTTFLRTLNRMNDKVSGyrysgDVLLGGRSIFNY--RDVLEFRRRVGMLFQRpnpFP 114
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 LLSSRTVFANI-AFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSAL 171
Cdd:PRK14271 115 MSIMDNVLAGVrAHKLVPRKEFRGVAQARLTEVGLWDAVKDRLSDSPFRLSGGQQQLLCLARTLAVNPEVLLLDEPTSAL 194
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 172 DPQTTRSILSLLKEINVKlgLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAK 233
Cdd:PRK14271 195 DPTTTEKIEEFIRSLADR--LTVIIVTHNLAQAARISDRAALFFDGRLVEEGPTEQLFSSPK 254
|
|
| MK0520 |
COG2401 |
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction ... |
11-214 |
7.08e-25 |
|
ABC-type ATPase fused to a predicted acetyltransferase domain [General function prediction only];
Pssm-ID: 441957 [Multi-domain] Cd Length: 222 Bit Score: 100.42 E-value: 7.08e-25
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDAV--HALRDVSLHVPQGKIFGVIGASGAGKSTLIRCV--NLLERPTEGQVIVDGQDLvalpERELTLARrqigm 86
Cdd:COG2401 34 FGVELRVVerYVLRDLNLEIEPGEIVLIVGASGSGKSTLLRLLagALKGTPVAGCVDVPDNQF----GREASLID----- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 87 ifqhfNLLSSRTVFANIafplelagwsksqirarvdELLALVGLeARAHAY---PSELSGGQKQRVAIARALAPAPKVLL 163
Cdd:COG2401 105 -----AIGRKGDFKDAV-------------------ELLNAVGL-SDAVLWlrrFKELSTGQKFRFRLALLLAERPKLLV 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 754651031 164 CDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAII 214
Cdd:COG2401 160 IDEFCSHLDRQTAKRVARNLQKLARRAGITLVVATHHYDVIDDLQPDLLIF 210
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
13-220 |
1.16e-24 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 104.24 E-value: 1.16e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 13 KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLeRPT---EGQVIVDGQDLVALPERELTlaRRQIGMIFQ 89
Cdd:PRK13549 13 KTFGGVKALDNVSLKVRAGEIVSLCGENGAGKSTLMKVLSGV-YPHgtyEGEIIFEGEELQASNIRDTE--RAGIAIIHQ 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 90 HFNLLSSRTVFANIAFPLEL--AG---WSKSQIRArvDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLC 164
Cdd:PRK13549 90 ELALVKELSVLENIFLGNEItpGGimdYDAMYLRA--QKLLAQLKLDINPATPVGNLGLGQQQLVEIAKALNKQARLLIL 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 165 DEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:PRK13549 168 DEPTASLTESETAVLLDIIRDLKAH-GIACIYISHKLNEVKAISDTICVIRDGRHI 222
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
1-226 |
1.58e-24 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 103.93 E-value: 1.58e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYgkgsDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA 80
Cdd:PRK10762 4 LLQLKGIDKAF----PGVKALSGAALNVYPGRVMALVGENGAGKSTMMKVLTGIYTRDAGSILYLGKEVTFNGPKSSQEA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rrQIGMIFQHFNLLSSRTVFANIAFPLELAG------WSKsqIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:PRK10762 80 --GIGIIHQELNLIPQLTIAENIFLGREFVNrfgridWKK--MYAEADKLLARLNLRFSSDKLVGELSIGEQQMVEIAKV 155
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:PRK10762 156 LSFESKVIIMDEPTDALTDTETESLFRVIRELKSQ-GRGIVYISHRLKEIFEICDDVTVFRDGQFIAEREVA 226
|
|
| PRK10261 |
PRK10261 |
glutathione transporter ATP-binding protein; Provisional |
1-229 |
2.17e-24 |
|
glutathione transporter ATP-binding protein; Provisional
Pssm-ID: 182342 [Multi-domain] Cd Length: 623 Bit Score: 104.17 E-value: 2.17e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKS-TLIRCVNLLERpTEGQVIVDG-------QDLVAL 72
Cdd:PRK10261 12 VLAVENLNIAFMQEQQKIAAVRNLSFSLQRGETLAIVGESGSGKSvTALALMRLLEQ-AGGLVQCDKmllrrrsRQVIEL 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 73 PERELTLARR----QIGMIFQHfNLLSSRTVFA---NIAFPLEL-AGWSKSQIRARVDELLALVGL---EARAHAYPSEL 141
Cdd:PRK10261 91 SEQSAAQMRHvrgaDMAMIFQE-PMTSLNPVFTvgeQIAESIRLhQGASREEAMVEAKRMLDQVRIpeaQTILSRYPHQL 169
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 142 SGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:PRK10261 170 SGGMRQRVMIAMALSCRPAVLIADEPTTALDVTIQAQILQLIKVLQKEMSMGVIFITHDMGVVAEIADRVLVMYQGEAVE 249
|
....*...
gi 754651031 222 QGEVAWFF 229
Cdd:PRK10261 250 TGSVEQIF 257
|
|
| PRK15056 |
PRK15056 |
manganese/iron ABC transporter ATP-binding protein; |
20-237 |
5.48e-24 |
|
manganese/iron ABC transporter ATP-binding protein;
Pssm-ID: 185016 [Multi-domain] Cd Length: 272 Bit Score: 99.19 E-value: 5.48e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQHFNLLSSRTV 99
Cdd:PRK15056 22 ALRDASFTVPGGSIAALVGVNGSGKSTLFKALMGFVRLASGKISILGQPTRQALQKNLVAYVPQSEEVDWSFPVLVEDVV 101
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSI 179
Cdd:PRK15056 102 MMGRYGHMGWLRRAKKRDRQIVTAALARVDMVEFRHRQIGELSGGQKKRVFLARAIAQQGQVILLDEPFTGVDVKTEARI 181
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 180 LSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISdGSLIEQGEVAWFFSNAKTQLA 237
Cdd:PRK15056 182 ISLLRELRDE-GKTMLVSTHNLGSVTEFCDYTVMVK-GTVLASGPTETTFTAENLELA 237
|
|
| ABCC_NFT1 |
cd03369 |
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type ... |
2-223 |
5.94e-24 |
|
ATP-binding cassette domain 2 of NFT1, subfamily C; Domain 2 of NFT1 (New full-length MRP-type transporter 1). NFT1 belongs to the MRP (multidrug resistance-associated protein) family of ABC transporters. Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213269 [Multi-domain] Cd Length: 207 Bit Score: 97.48 E-value: 5.94e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:cd03369 7 IEVENLSVRYA--PDLPPVLKNVSFKVKAGEKIGIVGRTGAGKSTLILALFRFLEAEEGKIEIDGIDISTIPLEDL---R 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIAFPLElagWSKSQIRArvdellALvgleaRAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03369 82 SSLTIIPQDPTLFSG-TIRSNLDPFDE---YSDEEIYG------AL-----RVSEGGLNLSQGQRQLLCLARALLKRPRV 146
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:cd03369 147 LVLDEATASIDYATDALIQKTIREEFT--NSTILTIAHRLRTIID-YDKILVMDAGEVKEYD 205
|
|
| livF |
PRK11614 |
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF; |
1-237 |
6.03e-24 |
|
high-affinity branched-chain amino acid ABC transporter ATP-binding protein LivF;
Pssm-ID: 183231 [Multi-domain] Cd Length: 237 Bit Score: 98.41 E-value: 6.03e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTla 80
Cdd:PRK11614 5 MLSFDKVSAHYGK----IQALHEVSLHINQGEIVTLIGANGAGKTTLLGTLCGDPRATSGRIVFDGKDITDWQTAKIM-- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFQHFNLLSSRTVFANIAFPLELAgwSKSQIRARVDELLALVG-LEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:PRK11614 79 REAVAIVPEGRRVFSRMTVEENLAMGGFFA--ERDQFQERIKWVYELFPrLHERRIQRAGTMSGGEQQMLAIGRALMSQP 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWFFSNAKTQLA 237
Cdd:PRK11614 157 RLLLLDEPSLGLAPIIIQQIFDTIEQLREQ-GMTIFLVEQNANQALKLADRGYVLENGHVVLEDTGDALLANEAVRSA 233
|
|
| ArpD |
COG4618 |
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular ... |
21-224 |
1.45e-23 |
|
ABC-type protease/lipase transport system, ATPase and permease components [Intracellular trafficking, secretion, and vesicular transport];
Pssm-ID: 443660 [Multi-domain] Cd Length: 563 Bit Score: 101.36 E-value: 1.45e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRC-VNLLeRPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLSSrTV 99
Cdd:COG4618 348 LRGVSFSLEPGEVLGVIGPSGSGKSTLARLlVGVW-PPTAGSVRLDGADLSQWDREEL---GRHIGYLPQDVELFDG-TI 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIA-FP-------LELAgwsksqIRARVDEL-LAL-------VGlEARAHaypseLSGGQKQRVAIARALAPAPKVLL 163
Cdd:COG4618 423 AENIArFGdadpekvVAAA------KLAGVHEMiLRLpdgydtrIG-EGGAR-----LSGGQRQRIGLARALYGDPRLVV 490
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 164 CDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVkGICDDVAIISDGSLIEQGE 224
Cdd:COG4618 491 LDEPNSNLDDEGEAALAAAIRALK-ARGATVVVITHRPSLL-AAVDKLLVLRDGRVQAFGP 549
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
1-220 |
1.85e-23 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 101.05 E-value: 1.85e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIR--CVNLLERPTEGQVIVDGQDLVALPERELT 78
Cdd:TIGR02633 1 LLEMKGIVKTFG----GVKALDGIDLEVRPGECVGLCGENGAGKSTLMKilSGVYPHGTWDGEIYWSGSPLKASNIRDTE 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 laRRQIGMIFQHFNLLSSRTVFANIAFPLEL----AGWSKSQIRARVDELLALVGLEARAHAYP-SELSGGQKQRVAIAR 153
Cdd:TIGR02633 77 --RAGIVIIHQELTLVPELSVAENIFLGNEItlpgGRMAYNAMYLRAKNLLRELQLDADNVTRPvGDYGGGQQQLVEIAK 154
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 154 ALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:TIGR02633 155 ALNKQARLLILDEPSSSLTEKETEILLDIIRDLKAH-GVACVYISHKLNEVKAVCDTICVIRDGQHV 220
|
|
| PRK11160 |
PRK11160 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
2-223 |
2.07e-23 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236865 [Multi-domain] Cd Length: 574 Bit Score: 101.05 E-value: 2.07e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDavHALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLER---PTEGQVIVDGQDLVALPERELt 78
Cdd:PRK11160 339 LTLNNVSFTYPDQPQ--PVLKGLSLQIKAGEKVALLGRTGCGKSTLL---QLLTRawdPQQGEILLNGQPIADYSEAAL- 412
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 laRRQIGMIFQHFNLLSSrTVFANIAFPLELAGwsksqiRARVDELLALVGLEARAHAYPS----------ELSGGQKQR 148
Cdd:PRK11160 413 --RQAISVVSQRVHLFSA-TLRDNLLLAAPNAS------DEALIEVLQQVGLEKLLEDDKGlnawlgeggrQLSGGEQRR 483
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 149 VAIARA-LAPAPKVLLcDEATSALDPQTTRSILSLLKEinVKLGLTILLITH------EMDVvkgICddvaIISDGSLIE 221
Cdd:PRK11160 484 LGIARAlLHDAPLLLL-DEPTEGLDAETERQILELLAE--HAQNKTVLMITHrltgleQFDR---IC----VMDNGQIIE 553
|
..
gi 754651031 222 QG 223
Cdd:PRK11160 554 QG 555
|
|
| NIL |
smart00930 |
This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine ... |
265-339 |
2.92e-23 |
|
This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins; This domain is likely to act as a substrate binding domain. The domain has been named after a conserved sequence in some members of the family.
Pssm-ID: 197998 [Multi-domain] Cd Length: 76 Bit Score: 91.42 E-value: 2.92e-23
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 265 SYPLVKLGFTGSTVDTPLISEASRRFNIDISILSADIEYAGGVKFGFLLAELFGDEAQCEATQQFLIDNHIQLEV 339
Cdd:smart00930 1 DGRLVRLTFTGESADEPLISQLAREFGVDVNILHGNIERIQGGPFGSLVVELTGDEEDIEAALAYLREQGVEVEV 75
|
|
| PRK15093 |
PRK15093 |
peptide ABC transporter ATP-binding protein SapD; |
18-221 |
7.25e-23 |
|
peptide ABC transporter ATP-binding protein SapD;
Pssm-ID: 185049 [Multi-domain] Cd Length: 330 Bit Score: 97.18 E-value: 7.25e-23
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCV------NLleRPTEGQVIVDGQDLVALPEREL-TLARRQIGMIFQH 90
Cdd:PRK15093 20 VKAVDRVSMTLTEGEIRGLVGESGSGKSLIAKAIcgvtkdNW--RVTADRMRFDDIDLLRLSPRERrKLVGHNVSMIFQE 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 FN--LLSSRTVFANI--AFPlelaGWS-KSQIRARVD-------ELLALVGLEAR---AHAYPSELSGGQKQRVAIARAL 155
Cdd:PRK15093 98 PQscLDPSERVGRQLmqNIP----GWTyKGRWWQRFGwrkrraiELLHRVGIKDHkdaMRSFPYELTEGECQKVMIAIAL 173
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:PRK15093 174 ANQPRLLIADEPTNAMEPTTQAQIFRLLTRLNQNNNTTILLISHDLQMLSQWADKINVLYCGQTVE 239
|
|
| CydC |
TIGR02868 |
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family ... |
16-199 |
1.41e-22 |
|
thiol reductant ABC exporter, CydC subunit; The gene pair cydCD encodes an ABC-family transporter in which each gene contains an N-terminal membrane-spanning domain (pfam00664) and a C-terminal ATP-binding domain (pfam00005). In E. coli these genes were discovered as mutants which caused the terminal heme-copper oxidase complex cytochrome bd to fail to assemble. Recent work has shown that the transporter is involved in export of redox-active thiol compounds such as cysteine and glutathione. The linkage to assembly of the cytochrome bd complex is further supported by the conserved operon structure found outside the gammaproteobacteria (cydABCD) containing both the transporter and oxidase genes components. The genes used as the seed members for this model are all either found in the gammproteobacterial context or the CydABCD context. All members of this family scoring above trusted at the time of its creation were from genomes which encode a cytochrome bd complex.
Pssm-ID: 274331 [Multi-domain] Cd Length: 530 Bit Score: 98.59 E-value: 1.41e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 16 DAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLS 95
Cdd:TIGR02868 346 GAPPVLDGVSLDLPPGERVAILGPSGSGKSTLLATLAGLLDPLQGEVTLDGVPVSSLDQDEV---RRRVSVCAQDAHLFD 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SrTVFANIAF-----PLELAGWSKSqiRARVDELLALV--GLEARAHAYPSELSGGQKQRVAIARAL-APAPkVLLCDEA 167
Cdd:TIGR02868 423 T-TVRENLRLarpdaTDEELWAALE--RVGLADWLRALpdGLDTVLGEGGARLSGGERQRLALARALlADAP-ILLLDEP 498
|
170 180 190
....*....|....*....|....*....|..
gi 754651031 168 TSALDPQTTRSILSLLkeINVKLGLTILLITH 199
Cdd:TIGR02868 499 TEHLDAETADELLEDL--LAALSGRTVVLITH 528
|
|
| PRK11174 |
PRK11174 |
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed |
24-223 |
6.79e-22 |
|
cysteine/glutathione ABC transporter membrane/ATP-binding component; Reviewed
Pssm-ID: 236870 [Multi-domain] Cd Length: 588 Bit Score: 96.45 E-value: 6.79e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 24 VSLHVPQGKIFGVIGASGAGKSTLIrcvNLLE--RPTEGQVIVDGQDLvalpeRELTLA--RRQIGMIFQHFNLLSSrTV 99
Cdd:PRK11174 369 LNFTLPAGQRIALVGPSGAGKTSLL---NALLgfLPYQGSLKINGIEL-----RELDPEswRKHLSWVGQNPQLPHG-TL 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLELAgwSKSQI-----RARVDELLALV--GLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK11174 440 RDNVLLGNPDA--SDEQLqqaleNAWVSEFLPLLpqGLDTPIGDQAAGLSVGQAQRLALARALLQPCQLLLLDEPTASLD 517
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 754651031 173 PQTTRSILSLLKEInvKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:PRK11174 518 AHSEQLVMQALNAA--SRRQTTLMVTHQLEDLAQ-WDQIWVMQDGQIVQQG 565
|
|
| PRK10253 |
PRK10253 |
iron-enterobactin ABC transporter ATP-binding protein; |
3-223 |
8.05e-22 |
|
iron-enterobactin ABC transporter ATP-binding protein;
Pssm-ID: 182336 [Multi-domain] Cd Length: 265 Bit Score: 93.13 E-value: 8.05e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 3 KLNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTlarR 82
Cdd:PRK10253 7 RLRGEQLTLGYGKYTV--AENLTVEIPDGHFTAIIGPNGCGKSTLLRTLSRLMTPAHGHVWLDGEHIQHYASKEVA---R 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 QIGMIFQHFNLLSSRTVFANIA---FPLE--LAGWSKSQIRArVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:PRK10253 82 RIGLLAQNATTPGDITVQELVArgrYPHQplFTRWRKEDEEA-VTKAMQATGITHLADQSVDTLSGGQRQRAWIAMVLAQ 160
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQG 223
Cdd:PRK10253 161 ETAIMLLDEPTTWLDISHQIDLLELLSELNREKGYTLAAVLHDLNQACRYASHLIALREGKIVAQG 226
|
|
| bacteriocin_ABC |
TIGR01193 |
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The ... |
2-224 |
3.24e-21 |
|
ABC-type bacteriocin transporter; This model describes ABC-type bacteriocin transporter. The amino terminal domain (pfam03412) processes the N-terminal leader peptide from the bacteriocin while C-terminal domains resemble ABC transporter membrane protein and ATP-binding cassette domain. In general, bacteriocins are agents which are responsible for killing or inhibiting the closely related species or even different strains of the same species. Bacteriocins are usually encoded by bacterial plasmids. Bacteriocins are named after the species and hence in literature one encounters various names e.g., leucocin from Leuconostic geldium; pedicocin from Pedicoccus acidilactici; sakacin from Lactobacillus sake etc. [Protein fate, Protein and peptide secretion and trafficking, Protein fate, Protein modification and repair, Transport and binding proteins, Other]
Pssm-ID: 130261 [Multi-domain] Cd Length: 708 Bit Score: 94.81 E-value: 3.24e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAVHalrDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaR 81
Cdd:TIGR01193 474 IVINDVSYSYGYGSNILS---DISLTIKMNSKTTIVGMSGSGKSTLAKLLVGFFQARSGEILLNGFSLKDIDRHTL---R 547
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 RQIGMIFQHFNLLSSrTVFANIafpleLAGWSKSQIRARVDELLALV-----------GLEARAHAYPSELSGGQKQRVA 150
Cdd:TIGR01193 548 QFINYLPQEPYIFSG-SILENL-----LLGAKENVSQDEIWAACEIAeikddienmplGYQTELSEEGSSISGGQKQRIA 621
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 151 IARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlglTILLITHEMDVVKGIcDDVAIISDGSLIEQGE 224
Cdd:TIGR01193 622 LARALLTDSKVLILDESTSNLDTITEKKIVNNLLNLQDK---TIIFVAHRLSVAKQS-DKIIVLDHGKIIEQGS 691
|
|
| MglA |
COG1129 |
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism]; |
19-226 |
4.63e-21 |
|
ABC-type sugar transport system, ATPase component [Carbohydrate transport and metabolism];
Pssm-ID: 440745 [Multi-domain] Cd Length: 497 Bit Score: 93.93 E-value: 4.63e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDL------------VAL-PEreltlARRQIG 85
Cdd:COG1129 266 GVVRDVSFSVRAGEILGIAGLVGAGRTELARALFGADPADSGEIRLDGKPVrirsprdairagIAYvPE-----DRKGEG 340
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 86 mifqhfnLLSSRTVFANIAFP----LELAGW-SKSQIRARVDELLALVGLEARAHAYP-SELSGGQKQRVAIARALAPAP 159
Cdd:COG1129 341 -------LVLDLSIRENITLAsldrLSRGGLlDRRRERALAEEYIKRLRIKTPSPEQPvGNLSGGNQQKVVLAKWLATDP 413
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 160 KVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIeqGEVA 226
Cdd:COG1129 414 KVLILDEPTRGIDVGAKAEIYRLIREL-AAEGKAVIVISSELPELLGLSDRILVMREGRIV--GELD 477
|
|
| YddA |
COG4178 |
ABC-type uncharacterized transport system, permease and ATPase components [General function ... |
21-199 |
6.05e-21 |
|
ABC-type uncharacterized transport system, permease and ATPase components [General function prediction only];
Pssm-ID: 443337 [Multi-domain] Cd Length: 571 Bit Score: 93.72 E-value: 6.05e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIV-DGQDLVALPER----ELTLaRRQIgmifqhfnlls 95
Cdd:COG4178 379 LEDLSLSLKPGERLLITGPSGSGKSTLLRAIAGLWPYGSGRIARpAGARVLFLPQRpylpLGTL-REAL----------- 446
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 srtvfaniAFPLELAGWSKSQIRarvdELLALVGLEARAH------AYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:COG4178 447 --------LYPATAEAFSDAELR----EALEAVGLGHLAErldeeaDWDQVLSLGEQQRLAFARLLLHKPDWLFLDEATS 514
|
170 180 190
....*....|....*....|....*....|.
gi 754651031 170 ALDPQTTRSILSLLKEinvKL-GLTILLITH 199
Cdd:COG4178 515 ALDEENEAALYQLLRE---ELpGTTVISVGH 542
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
4-199 |
7.75e-21 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 93.21 E-value: 7.75e-21
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGkgsdAVHALRDVSLHVPQG-KIfGVIGASGAGKSTLIRCVNLLERPTEGQVIVDG--------QDLVALPE 74
Cdd:COG0488 1 LENLSKSFG----GRPLLDDVSLSINPGdRI-GLVGRNGAGKSTLLKILAGELEPDSGEVSIPKglrigylpQEPPLDDD 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 75 R----ELTLARRQIGMIFQHFNLLSSRTVFANiAFPLELA----------GWSksqIRARVDELLALVGLEARAHAYP-S 139
Cdd:COG0488 76 LtvldTVLDGDAELRALEAELEELEAKLAEPD-EDLERLAelqeefealgGWE---AEARAEEILSGLGFPEEDLDRPvS 151
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 140 ELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVklglTILLITH 199
Cdd:COG0488 152 ELSGGWRRRVALARALLSEPDLLLLDEPTNHLDLESIEWLEEFLKNYPG----TVLVVSH 207
|
|
| ABCC_cytochrome_bd |
cd03247 |
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome ... |
19-223 |
1.55e-20 |
|
ATP-binding cassette domain of CydCD, subfamily C; The CYD subfamily implicated in cytochrome bd biogenesis. The CydC and CydD proteins are important for the formation of cytochrome bd terminal oxidase of E. coli and it has been proposed that they were necessary for biosynthesis of the cytochrome bd quinol oxidase and for periplasmic c-type cytochromes. CydCD were proposed to determine a heterooligomeric complex important for heme export into the periplasm or to be involved in the maintenance of the proper redox state of the periplasmic space. In Bacillus subtilis, the absence of CydCD does not affect the presence of halo-cytochrome c in the membrane and this observation suggests that CydCD proteins are not involved in the export of heme in this organism.
Pssm-ID: 213214 [Multi-domain] Cd Length: 178 Bit Score: 87.37 E-value: 1.55e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKSTLIRcvnLLER---PTEGQVIVDGQDLVALPEreltLARRQIGMIFQHFNLLS 95
Cdd:cd03247 16 QVLKNLSLELKQGEKIALLGRSGSGKSTLLQ---LLTGdlkPQQGEITLDGVPVSDLEK----ALSSLISVLNQRPYLFD 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SrTVFANIAFPLelagwsksqirarvdellalvglearahaypselSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:cd03247 89 T-TLRNNLGRRF----------------------------------SGGERQRLALARILLQDAPIVLLDEPTVGLDPIT 133
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 754651031 176 TRSILSLLKEinVKLGLTILLITHEMDVVKGIcDDVAIISDGSLIEQG 223
Cdd:cd03247 134 ERQLLSLIFE--VLKDKTLIWITHHLTGIEHM-DKILFLENGKIIMQG 178
|
|
| NIL |
pfam09383 |
NIL domain; This domain is found at the C-terminus of ABC transporter proteins involved in ... |
267-339 |
2.58e-20 |
|
NIL domain; This domain is found at the C-terminus of ABC transporter proteins involved in D-methionine transport as well as a number of ferredoxin-like proteins. This domain is likely to act as a substrate binding domain. The domain has been named after a conserved sequence in some members of the family.
Pssm-ID: 462781 [Multi-domain] Cd Length: 73 Bit Score: 83.65 E-value: 2.58e-20
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 267 PLVKLGFTGSTVDTPLISEASRRFNIDISILSADIEYAGGVKFGFLLAELFGDEAQCEATQQFLIDNHIQLEV 339
Cdd:pfam09383 1 RLVRLTFPGESADEPVISRLAREFGVDVNILYGNIEEIQGTPFGSLILELPGDPEQIEAALAYLREQGVEVEV 73
|
|
| NupO |
COG3845 |
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and ... |
13-226 |
4.37e-20 |
|
ABC-type guanosine uptake system NupNOPQ, ATPase component NupO [Nucleotide transport and metabolism];
Pssm-ID: 443055 [Multi-domain] Cd Length: 504 Bit Score: 90.86 E-value: 4.37e-20
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 13 KGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPEREltlaRRQIGMIF---- 88
Cdd:COG3845 266 RDDRGVPALKDVSLEVRAGEILGIAGVAGNGQSELAEALAGLRPPASGSIRLDGEDITGLSPRE----RRRLGVAYiped 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 89 -QHFNLLSSRTVFANIAF------PLELAGW-SKSQIRARVDELLA-----LVGLEARAhaypSELSGGQKQRVAIARAL 155
Cdd:COG3845 342 rLGRGLVPDMSVAENLILgryrrpPFSRGGFlDRKAIRAFAEELIEefdvrTPGPDTPA----RSLSGGNQQKVILAREL 417
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIeqGEVA 226
Cdd:COG3845 418 SRDPKLLIAAQPTRGLDVGAIEFIHQRLLELRDA-GAAVLLISEDLDEILALSDRIAVMYEGRIV--GEVP 485
|
|
| Uup |
COG0488 |
ATPase components of ABC transporters with duplicated ATPase domains [General function ... |
1-221 |
1.39e-19 |
|
ATPase components of ABC transporters with duplicated ATPase domains [General function prediction only];
Pssm-ID: 440254 [Multi-domain] Cd Length: 520 Bit Score: 89.35 E-value: 1.39e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVdGQDLvalpereltla 80
Cdd:COG0488 315 VLELEGLSKSYG----DKTLLDDLSLRIDRGDRIGLIGPNGAGKSTLLKLLAGELEPDSGTVKL-GETV----------- 378
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 rrQIGMIFQHFNLL-SSRTVFANIAfplELA-GWSKSQIRArvdeLLALVGL-EARAHAYPSELSGGQKQRVAIARALAP 157
Cdd:COG0488 379 --KIGYFDQHQEELdPDKTVLDELR---DGApGGTEQEVRG----YLGRFLFsGDDAFKPVGVLSGGEKARLALAKLLLS 449
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 158 APKVLLCDEATSALDPQTTRSILSLLKEINvklGlTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:COG0488 450 PPNVLLLDEPTNHLDIETLEALEEALDDFP---G-TVLLVSHDRYFLDRVATRILEFEDGGVRE 509
|
|
| 3a01204 |
TIGR00955 |
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, ... |
19-231 |
1.59e-19 |
|
The Eye Pigment Precursor Transporter (EPP) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273361 [Multi-domain] Cd Length: 617 Bit Score: 89.72 E-value: 1.59e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLERPTEGQVIVDGQDLVALPERELTLARRQIGMIFQHFNLLSSRT 98
Cdd:TIGR00955 39 HLLKNVSGVAKPGELLAVMGSSGAGKTTLM---NALAFRSPKGVKGSGSVLLNGMPIDAKEMRAISAYVQQDDLFIPTLT 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPLEL---AGWSKSQIRARVDELLALVGLEARAH------AYPSELSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:TIGR00955 116 VREHLMFQAHLrmpRRVTKKEKRERVDEVLQALGLRKCANtrigvpGRVKGLSGGERKRLAFASELLTDPPLLFCDEPTS 195
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 170 ALDPQTTRSILSLLKEINVKlGLTILLITHEMDV-VKGICDDVAIISDGSLIEQG---EVAWFFSN 231
Cdd:TIGR00955 196 GLDSFMAYSVVQVLKGLAQK-GKTIICTIHQPSSeLFELFDKIILMAEGRVAYLGspdQAVPFFSD 260
|
|
| PRK10790 |
PRK10790 |
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein; |
2-223 |
2.25e-19 |
|
SmdB family multidrug efflux ABC transporter permease/ATP-binding protein;
Pssm-ID: 182733 [Multi-domain] Cd Length: 592 Bit Score: 89.01 E-value: 2.25e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSDAvhaLRDVSLHVPQGKIFGVIGASGAGKSTLircVNLLE---RPTEGQVIVDGQDLVALPERELt 78
Cdd:PRK10790 341 IDIDNVSFAYRDDNLV---LQNINLSVPSRGFVALVGHTGSGKSTL---ASLLMgyyPLTEGEIRLDGRPLSSLSHSVL- 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 79 laRRQIGMIFQHFNLLSSrTVFANIAFPLELAgwsksqiRARVDELLALVGLEARAHAYP-----------SELSGGQKQ 147
Cdd:PRK10790 414 --RQGVAMVQQDPVVLAD-TFLANVTLGRDIS-------EEQVWQALETVQLAELARSLPdglytplgeqgNNLSVGQKQ 483
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 148 RVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlgLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:PRK10790 484 LLALARVLVQTPQILILDEATANIDSGTEQAIQQALAAVREH--TTLVVIAHRLSTIVE-ADTILVLHRGQAVEQG 556
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
18-221 |
5.73e-19 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 87.54 E-value: 5.73e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLE--RPT---EGQVIVDGQdlvalpERELTLAR----RQIGMIF 88
Cdd:NF040905 14 VKALDDVNLSVREGEIHALCGENGAGKSTLM---KVLSgvYPHgsyEGEILFDGE------VCRFKDIRdseaLGIVIIH 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 89 QHFNLLSSRTVFANIAFPLELA-----GWSKSQIRARvdELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLL 163
Cdd:NF040905 85 QELALIPYLSIAENIFLGNERAkrgviDWNETNRRAR--ELLAKVGLDESPDTLVTDIGVGKQQLVEIAKALSKDVKLLI 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 164 CDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:NF040905 163 LDEPTAALNEEDSAALLDLLLELKAQ-GITSIIISHKLNEIRRVADSITVLRDGRTIE 219
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
20-201 |
9.64e-19 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 87.49 E-value: 9.64e-19
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVN-LLErPTEGQVIVDGQDLVAlpeRELTlARRQIGMIFQHFNLLSSRT 98
Cdd:NF033858 281 AVDHVSFRIRRGEIFGFLGSNGCGKSTTMKMLTgLLP-ASEGEAWLFGQPVDA---GDIA-TRRRVGYMSQAFSLYGELT 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:NF033858 356 VRQNLELHARLFHLPAAEIAARVAEMLERFDLADVADALPDSLPLGIRQRLSLAVAVIHKPELLILDEPTSGVDPVARDM 435
|
170 180
....*....|....*....|...
gi 754651031 179 ILSLLKEINVKLGLTILLITHEM 201
Cdd:NF033858 436 FWRLLIELSREDGVTIFISTHFM 458
|
|
| ABCC_MRP_domain1 |
cd03250 |
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This ... |
20-218 |
5.76e-18 |
|
ATP-binding cassette domain 1 of multidrug resistance-associated protein, subfamily C; This subfamily is also known as MRP (multidrug resistance-associated protein). Some of the MRP members have five additional transmembrane segments in their N-terminus, but the function of these additional membrane-spanning domains is not clear. The MRP was found in the multidrug-resisting lung cancer cell in which p-glycoprotein was not overexpressed. MRP exports glutathione by drug stimulation, as well as, certain substrates in conjugated forms with anions, such as glutathione, glucuronate, and sulfate.
Pssm-ID: 213217 [Multi-domain] Cd Length: 204 Bit Score: 80.98 E-value: 5.76e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVnLLE-RPTEGQVIVDGQD-LVAlpereltlarrQIGMIFqhfnllsSR 97
Cdd:cd03250 20 TLKDINLEVPKGELVAIVGPVGSGKSSLLSAL-LGElEKLSGSVSVPGSIaYVS-----------QEPWIQ-------NG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFPLEL-AGWSKSQIRA---RVD-ELLAL-----VGlearahaypsE----LSGGQKQRVAIARALAPAPKVLL 163
Cdd:cd03250 81 TIRENILFGKPFdEERYEKVIKAcalEPDlEILPDgdlteIG----------EkginLSGGQKQRISLARAVYSDADIYL 150
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 164 CDEATSALDPQTTRSIL-SLLKEiNVKLGLTILLITHEMDVVKgICDDVAIISDGS 218
Cdd:cd03250 151 LDDPLSAVDAHVGRHIFeNCILG-LLLNNKTRILVTHQLQLLP-HADQIVVLDNGR 204
|
|
| BtuD |
COG4138 |
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism]; ... |
21-226 |
1.00e-17 |
|
ABC-type cobalamin transport system, ATPase component BtuD [Coenzyme transport and metabolism];
Pssm-ID: 443313 [Multi-domain] Cd Length: 248 Bit Score: 81.43 E-value: 1.00e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLerPTEGQVIVDGQDLVALPEREltLARRQiGMIFQHFNLLSSRTV 99
Cdd:COG4138 12 LGPISAQVNAGELIHLIGPNGAGKSTLLARMaGLL--PGQGEILLNGRPLSDWSAAE--LARHR-AYLSQQQSPPFAMPV 86
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLElAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA-------PAPKVLLCDEATSALD 172
Cdd:COG4138 87 FQYLALHQP-AGASSEAVEQLLAQLAEALGLEDKLSRPLTQLSGGEWQRVRLAAVLLqvwptinPEGQLLLLDEPMNSLD 165
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 754651031 173 PQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:COG4138 166 VAQQAALDRLLREL-CQQGITVVMSSHDLNHTLRHADRVWLLKQGKLVASGETA 218
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
21-200 |
1.30e-17 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 84.39 E-value: 1.30e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCvnLLERPTEGqVIVDGQDLVALPERELTLARRqIGMIFQHFNLLSSRTVF 100
Cdd:TIGR00956 779 LNNVDGWVKPGTLTALMGASGAGKTTLLNV--LAERVTTG-VITGGDRLVNGRPLDSSFQRS-IGYVQQQDLHLPTSTVR 854
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPLEL---AGWSKSQIRARVDELLALVGLEARAHAY---PSE-LSGGQKQRVAIARALAPAPKVLL-CDEATSALD 172
Cdd:TIGR00956 855 ESLRFSAYLrqpKSVSKSEKMEYVEEVIKLLEMESYADAVvgvPGEgLNVEQRKRLTIGVELVAKPKLLLfLDEPTSGLD 934
|
170 180
....*....|....*....|....*...
gi 754651031 173 PQTTRSILSLLKEInVKLGLTILLITHE 200
Cdd:TIGR00956 935 SQTAWSICKLMRKL-ADHGQAILCTIHQ 961
|
|
| ABC_FeS_Assembly |
cd03217 |
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of ... |
21-223 |
1.37e-17 |
|
ABC-type transport system involved in Fe-S cluster assembly, ATPase component; Biosynthesis of iron-sulfur clusters (Fe-S) depends on multi-protein systems. The SUF system of E. coli and Erwinia chrysanthemi is important for Fe-S biogenesis under stressful conditions. The SUF system is made of six proteins: SufC is an atypical cytoplasmic ABC-ATPase, which forms a complex with SufB and SufD; SufA plays the role of a scaffold protein for assembly of iron-sulfur clusters and delivery to target proteins; SufS is a cysteine desulfurase which mobilizes the sulfur atom from cysteine and provides it to the cluster; SufE has no associated function yet.
Pssm-ID: 213184 [Multi-domain] Cd Length: 200 Bit Score: 79.88 E-value: 1.37e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCV--NLLERPTEGQVIVDGQDLVALP--EReltlARRQIGMIFQHfnllss 96
Cdd:cd03217 16 LKGVNLTIKKGEVHALMGPNGSGKSTLAKTImgHPKYEVTEGEILFKGEDITDLPpeER----ARLGIFLAFQY------ 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 rtvfaniafPLELAGwsksqirARVDELLALVGLearahaypsELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTT 176
Cdd:cd03217 86 ---------PPEIPG-------VKNADFLRYVNE---------GFSGGEKKRNEILQLLLLEPDLAILDEPDSGLDIDAL 140
|
170 180 190 200
....*....|....*....|....*....|....*....|....*...
gi 754651031 177 RSILSLLKEINvKLGLTILLITHEMDVVKGICDDVA-IISDGSLIEQG 223
Cdd:cd03217 141 RLVAEVINKLR-EEGKSVLIITHYQRLLDYIKPDRVhVLYDGRIVKSG 187
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
18-220 |
1.70e-17 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 83.24 E-value: 1.70e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTlaRRQIGMIFQHFNLLSSR 97
Cdd:PRK10982 11 VKALDNVNLKVRPHSIHALMGENGAGKSTLLKCLFGIYQKDSGSILFQGKEIDFKSSKEAL--ENGISMVHQELNLVLQR 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANI---AFPLElaGWSKSQ------IRARVDELlalvGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEAT 168
Cdd:PRK10982 89 SVMDNMwlgRYPTK--GMFVDQdkmyrdTKAIFDEL----DIDIDPRAKVATLSVSQMQMIEIAKAFSYNAKIVIMDEPT 162
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 169 SALdpqTTRSILSLLKEINvKL---GLTILLITHEMDVVKGICDDVAIISDGSLI 220
Cdd:PRK10982 163 SSL---TEKEVNHLFTIIR-KLkerGCGIVYISHKMEEIFQLCDEITILRDGQWI 213
|
|
| ABCD_peroxisomal_ALDP |
cd03223 |
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding ... |
21-199 |
2.36e-17 |
|
ATP-binding cassette domain of peroxisomal transporter, subfamily D; Peroxisomal ATP-binding cassette transporter (Pat) is involved in the import of very long-chain fatty acids (VLCFA) into the peroxisome. The peroxisomal membrane forms a permeability barrier for a wide variety of metabolites required for and formed during fatty acid beta-oxidation. To communicate with the cytoplasm and mitochondria, peroxisomes need dedicated proteins to transport such hydrophilic molecules across their membranes. X-linked adrenoleukodystrophy (X-ALD) is caused by mutations in the ALD gene, which encodes ALDP (adrenoleukodystrophy protein ), a peroxisomal integral membrane protein that is a member of the ATP-binding cassette (ABC) transporter protein family. The disease is characterized by a striking and unpredictable variation in phenotypic expression. Phenotypes include the rapidly progressive childhood cerebral form (CCALD), the milder adult form, adrenomyeloneuropathy (AMN), and variants without neurologic involvement (i.e. asymptomatic).
Pssm-ID: 213190 [Multi-domain] Cd Length: 166 Bit Score: 78.35 E-value: 2.36e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIvdgqdlvaLPEREltlarrqiGMIFqhfnlLSSRTVF 100
Cdd:cd03223 17 LKDLSFEIKPGDRLLITGPSGTGKSSLFRALAGLWPWGSGRIG--------MPEGE--------DLLF-----LPQRPYL 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 AniafplelAGWSKSQIrarvdellalvglearahAYP--SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:cd03223 76 P--------LGTLREQL------------------IYPwdDVLSGGEQQRLAFARLLLHKPKFVFLDEATSALDEESEDR 129
|
170 180
....*....|....*....|.
gi 754651031 179 ILSLLKEinvkLGLTILLITH 199
Cdd:cd03223 130 LYQLLKE----LGITVISVGH 146
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
1-228 |
3.06e-17 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 82.41 E-value: 3.06e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVYGkgsdAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValperELTLA 80
Cdd:PRK15439 11 LLCARSISKQYS----GVEVLKGIDFTLHAGEVHALLGGNGAGKSTLMKIIAGIVPPDSGTLEIGGNPCA-----RLTPA 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQ---IGMIFQHFNLLSSRTVFANIAFplelaGWSKSQIR-ARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:PRK15439 82 KAHqlgIYLVPQEPLLFPNLSVKENILF-----GLPKRQASmQKMKQLLAALGCQLDLDSSAGSLEVADRQIVEILRGLM 156
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVAWF 228
Cdd:PRK15439 157 RDSRILILDEPTASLTPAETERLFSRIRELLAQ-GVGIVFISHKLPEIRQLADRISVMRDGTIALSGKTADL 227
|
|
| ABC2_perm_RbbA |
NF033858 |
ribosome-associated ATPase/putative transporter RbbA; |
2-173 |
4.46e-17 |
|
ribosome-associated ATPase/putative transporter RbbA;
Pssm-ID: 468210 [Multi-domain] Cd Length: 907 Bit Score: 82.48 E-value: 4.46e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLAR 81
Cdd:NF033858 2 ARLEGVSHRYGK----TVALDDVSLDIPAGCMVGLIGPDGVGKSSLLSLIAGARKIQQGRVEVLGGDMADARHRRAVCPR 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 rqIGMIFQHF--NLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAP 159
Cdd:NF033858 78 --IAYMPQGLgkNLYPTLSVFENLDFFGRLFGQDAAERRRRIDELLRATGLAPFADRPAGKLSGGMKQKLGLCCALIHDP 155
|
170
....*....|....
gi 754651031 160 KVLLCDEATSALDP 173
Cdd:NF033858 156 DLLILDEPTTGVDP 169
|
|
| PRK10789 |
PRK10789 |
SmdA family multidrug ABC transporter permease/ATP-binding protein; |
20-224 |
6.77e-17 |
|
SmdA family multidrug ABC transporter permease/ATP-binding protein;
Pssm-ID: 182732 [Multi-domain] Cd Length: 569 Bit Score: 81.68 E-value: 6.77e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIrcvNLLERP---TEGQVIVDGQdlvALPERELTLARRQIGMIFQHfNLLSS 96
Cdd:PRK10789 330 ALENVNFTLKPGQMLGICGPTGSGKSTLL---SLIQRHfdvSEGDIRFHDI---PLTKLQLDSWRSRLAVVSQT-PFLFS 402
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAfpLELAGWSKSQIR--ARV----DELLALvglearAHAYPSE-------LSGGQKQRVAIARALAPAPKVLL 163
Cdd:PRK10789 403 DTVANNIA--LGRPDATQQEIEhvARLasvhDDILRL------PQGYDTEvgergvmLSGGQKQRISIARALLLNAEILI 474
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 164 CDEATSALDPQTTRSILSLLKEInvKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGE 224
Cdd:PRK10789 475 LDDALSAVDGRTEHQILHNLRQW--GEGRTVIISAHRLSALTE-ASEILVMQHGHIAQRGN 532
|
|
| ccmA |
TIGR01189 |
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein ... |
20-199 |
1.03e-16 |
|
heme ABC exporter, ATP-binding protein CcmA; This model describes the cyt c biogenesis protein encoded by ccmA in bacteria. An exception is, an arabidopsis protein. Quite likely this is encoded by an organelle. Bacterial c-type cytocromes are located on the periplasmic side of the cytoplasmic membrane. Several gene products encoded in a locus designated as 'ccm' are implicated in the transport and assembly of the functional cytochrome C. This cluster includes genes: ccmA;B;C;D;E;F;G and H. The posttranslational pathway includes the transport of heme moiety, the secretion of the apoprotein and the covalent attachment of the heme with the apoprotein. The proteins ccmA and B represent an ABC transporter; ccmC and D participate in heme transfer to ccmE, which function as a periplasmic heme chaperone. The presence of ccmF, G and H is suggested to be obligatory for the final functional assembly of cytochrome c. [Protein fate, Protein and peptide secretion and trafficking, Transport and binding proteins, Other]
Pssm-ID: 273491 [Multi-domain] Cd Length: 198 Bit Score: 77.40 E-value: 1.03e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDL---VALPERELTLARRQIGMIfqhfNLLss 96
Cdd:TIGR01189 15 LFEGLSFTLNAGEALQVTGPNGIGKTTLLRILAGLLRPDSGEVRWNGTPLaeqRDEPHENILYLGHLPGLK----PEL-- 88
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 rTVFANIAFPLELAGWSksqiRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTT 176
Cdd:TIGR01189 89 -SALENLHFWAAIHGGA----QRTIEDALAAVGLTGFEDLPAAQLSAGQQRRLALARLWLSRRPLWILDEPTTALDKAGV 163
|
170 180
....*....|....*....|...
gi 754651031 177 RSILSLLKEINVKLGLtILLITH 199
Cdd:TIGR01189 164 ALLAGLLRAHLARGGI-VLLTTH 185
|
|
| znuC |
PRK09544 |
high-affinity zinc transporter ATPase; Reviewed |
21-211 |
2.05e-16 |
|
high-affinity zinc transporter ATPase; Reviewed
Pssm-ID: 181939 [Multi-domain] Cd Length: 251 Bit Score: 77.85 E-value: 2.05e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVivdgqdlvalpERELTLarrQIGMIFQHFNLlssrtvf 100
Cdd:PRK09544 20 LSDVSLELKPGKILTLLGPNGAGKSTLVRVVLGLVAPDEGVI-----------KRNGKL---RIGYVPQKLYL------- 78
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 aNIAFPLELAGWSKSQIRARVDELL-ALVGLEA-RAHAYP-SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTR 177
Cdd:PRK09544 79 -DTTLPLTVNRFLRLRPGTKKEDILpALKRVQAgHLIDAPmQKLSGGETQRVLLARALLNRPQLLVLDEPTQGVDVNGQV 157
|
170 180 190
....*....|....*....|....*....|....
gi 754651031 178 SILSLLKEINVKLGLTILLITHEMDVVKGICDDV 211
Cdd:PRK09544 158 ALYDLIDQLRRELDCAVLMVSHDLHLVMAKTDEV 191
|
|
| PRK03695 |
PRK03695 |
vitamin B12-transporter ATPase; Provisional |
24-224 |
2.94e-16 |
|
vitamin B12-transporter ATPase; Provisional
Pssm-ID: 235150 [Multi-domain] Cd Length: 248 Bit Score: 77.28 E-value: 2.94e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 24 VSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLerPTEGQVIVDGQDLVALPEREltLARRQiGMIFQHFNLLSSRTVFAN 102
Cdd:PRK03695 15 LSAEVRAGEILHLVGPNGAGKSTLLARMaGLL--PGSGSIQFAGQPLEAWSAAE--LARHR-AYLSQQQTPPFAMPVFQY 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 103 IAFPLElAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIA-------RALAPAPKVLLCDEATSALDPQT 175
Cdd:PRK03695 90 LTLHQP-DKTRTEAVASALNEVAEALGLDDKLGRSVNQLSGGEWQRVRLAavvlqvwPDINPAGQLLLLDEPMNSLDVAQ 168
|
170 180 190 200
....*....|....*....|....*....|....*....|....*....
gi 754651031 176 TRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:PRK03695 169 QAALDRLLSEL-CQQGIAVVMSSHDLNHTLRHADRVWLLKQGKLLASGR 216
|
|
| ABC_CcmA_heme_exporter |
cd03231 |
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the ... |
24-199 |
3.20e-16 |
|
Cytochrome c biogenesis ATP-binding export protein; CcmA, the ATP-binding component of the bacterial CcmAB transporter. The CCM family is involved in bacterial cytochrome c biogenesis. Cytochrome c maturation in E. coli requires the ccm operon, which encodes eight membrane proteins (CcmABCDEFGH). CcmE is a periplasmic heme chaperon that binds heme covalently and transfers it onto apocytochrome c in the presence of CcmF, CcmG, and CcmH. The CcmAB proteins represent an ABC transporter and the CcmCD proteins participate in heme transfer to CcmE.
Pssm-ID: 213198 [Multi-domain] Cd Length: 201 Bit Score: 75.99 E-value: 3.20e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 24 VSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvALPERELTLARrqiGMIF-QHFNLLSSR-TVFA 101
Cdd:cd03231 19 LSFTLAAGEALQVTGPNGSGKTTLLRILAGLSPPLAGRVLLNGG---PLDFQRDSIAR---GLLYlGHAPGIKTTlSVLE 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 102 NIAFplelagWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILS 181
Cdd:cd03231 93 NLRF------WHADHSDEQVEEALARVGLNGFEDRPVAQLSAGQQRRVALARLLLSGRPLWILDEPTTALDKAGVARFAE 166
|
170
....*....|....*...
gi 754651031 182 LLKEiNVKLGLTILLITH 199
Cdd:cd03231 167 AMAG-HCARGGMVVLTTH 183
|
|
| hmuV |
PRK13547 |
heme ABC transporter ATP-binding protein; |
21-226 |
3.61e-16 |
|
heme ABC transporter ATP-binding protein;
Pssm-ID: 184132 [Multi-domain] Cd Length: 272 Bit Score: 77.56 E-value: 3.61e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIR------CVNLLER--PTEGQVIVDGQDLVALPERELTLARRQIGMIFQHFN 92
Cdd:PRK13547 17 LRDLSLRIEPGRVTALLGRNGAGKSTLLKalagdlTGGGAPRgaRVTGDVTLNGEPLAAIDAPRLARLRAVLPQAAQPAF 96
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 LLSSRTVFANIAFP-LELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA---------PAPKVL 162
Cdd:PRK13547 97 AFSAREIVLLGRYPhARRAGALTHRDGEIAWQALALAGATALVGRDVTTLSGGELARVQFARVLAqlwpphdaaQPPRYL 176
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 163 LCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEVA 226
Cdd:PRK13547 177 LLDEPTAALDLAHQHRLLDTVRRLARDWNLGVLAIVHDPNLAARHADRIAMLADGAIVAHGAPA 240
|
|
| PRK13539 |
PRK13539 |
cytochrome c biogenesis protein CcmA; Provisional |
21-199 |
6.55e-16 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 237421 [Multi-domain] Cd Length: 207 Bit Score: 75.30 E-value: 6.55e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalperELTLARRQIGMIfQHFNLL-SSRTV 99
Cdd:PRK13539 18 FSGLSFTLAAGEALVLTGPNGSGKTTLLRLIAGLLPPAAGTIKLDGGDI------DDPDVAEACHYL-GHRNAMkPALTV 90
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLELAGwsksQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARAL-APAPkVLLCDEATSALDPQTTRS 178
Cdd:PRK13539 91 AENLEFWAAFLG----GEELDIAAALEAVGLAPLAHLPFGYLSAGQKRRVALARLLvSNRP-IWILDEPTAALDAAAVAL 165
|
170 180
....*....|....*....|.
gi 754651031 179 ILSLLKEiNVKLGLTILLITH 199
Cdd:PRK13539 166 FAELIRA-HLAQGGIVIAATH 185
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
11-243 |
1.07e-15 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 78.45 E-value: 1.07e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQH 90
Cdd:TIGR00957 1294 YREDLDLV--LRHINVTIHGGEKVGIVGRTGAGKSSLTLGLFRINESAEGEIIIDGLNIAKIGLHDL---RFKITIIPQD 1368
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 FNLLS----------SRTVFANIAFPLELAgwsksQIRARVDELLAlvGLEARAHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:TIGR00957 1369 PVLFSgslrmnldpfSQYSDEEVWWALELA-----HLKTFVSALPD--KLDHECAEGGENLSVGQRQLVCLARALLRKTK 1441
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTRSILSllkEINVKL-GLTILLITHEMDVvkgICDDVAIIsdgsLIEQGEVAWFFSNAKTQLARD 239
Cdd:TIGR00957 1442 ILVLDEATAAVDLETDNLIQS---TIRTQFeDCTVLTIAHRLNT---IMDYTRVI----VLDKGEVAEFGAPSNLLQQRG 1511
|
....
gi 754651031 240 FIHS 243
Cdd:TIGR00957 1512 IFYS 1515
|
|
| rim_protein |
TIGR01257 |
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim ... |
1-219 |
1.17e-15 |
|
retinal-specific rim ABC transporter; This model describes the photoreceptor protein (rim protein) in eukaryotes. It is the member of ABC transporter superfamily. Rim protein is a membrane glycoprotein which is localized in the photoreceptor outer segment discs. Mutation/s in its genetic loci is implicated in the recessive Stargardt's disease. [Transport and binding proteins, Other]
Pssm-ID: 130324 [Multi-domain] Cd Length: 2272 Bit Score: 78.52 E-value: 1.17e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 1 MIKLNGLNKVY-GKGSDAVHALrdvSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVAlperELTL 79
Cdd:TIGR01257 1937 ILRLNELTKVYsGTSSPAVDRL---CVGVRPGECFGLLGVNGAGKTTTFKMLTGDTTVTSGDATVAGKSILT----NISD 2009
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 ARRQIGMIFQHF---NLLSSRTvfaNIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALA 156
Cdd:TIGR01257 2010 VHQNMGYCPQFDaidDLLTGRE---HLYLYARLRGVPAEEIEKVANWSIQSLGLSLYADRLAGTYSGGNKRKLSTAIALI 2086
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:TIGR01257 2087 GCPPLVLLDEPTTGMDPQARRMLWNTIVSI-IREGRAVVLTSHSMEECEALCTRLAIMVKGAF 2148
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
18-205 |
1.80e-15 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 77.76 E-value: 1.80e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDgqDLVALPERELTLARRQIGMIFQHfNLLSSR 97
Cdd:PTZ00265 398 VEIYKDLNFTLTEGKTYAFVGESGCGKSTILKLIERLYDPTEGDIIIN--DSHNLKDINLKWWRSKIGVVSQD-PLLFSN 474
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFPL----ELAGWS----------------KSQIRARVDELLALVG--------LEARAH-------------- 135
Cdd:PTZ00265 475 SIKNNIKYSLyslkDLEALSnyynedgndsqenknkRNSCRAKCAGDLNDMSnttdsnelIEMRKNyqtikdsevvdvsk 554
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 136 ---------AYP-----------SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTIL 195
Cdd:PTZ00265 555 kvlihdfvsALPdkyetlvgsnaSKLSGGQKQRISIARAIIRNPKILILDEATSSLDNKSEYLVQKTINNLKGNENRITI 634
|
250
....*....|
gi 754651031 196 LITHEMDVVK 205
Cdd:PTZ00265 635 IIAHRLSTIR 644
|
|
| PRK13540 |
PRK13540 |
cytochrome c biogenesis protein CcmA; Provisional |
21-200 |
2.63e-15 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184127 [Multi-domain] Cd Length: 200 Bit Score: 73.45 E-value: 2.63e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLvalpERELTLARRQIGMIFQHFNLLSSRTVF 100
Cdd:PRK13540 17 LQQISFHLPAGGLLHLKGSNGAGKTTLLKLIAGLLNPEKGEILFERQSI----KKDLCTYQKQLCFVGHRSGINPYLTLR 92
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPLELagwskSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSIL 180
Cdd:PRK13540 93 ENCLYDIHF-----SPGAVGITELCRLFSLEHLIDYPCGLLSSGQKRQVALLRLWMSKAKLWLLDEPLVALDELSLLTII 167
|
170 180
....*....|....*....|
gi 754651031 181 SLLKEiNVKLGLTILLITHE 200
Cdd:PRK13540 168 TKIQE-HRAKGGAVLLTSHQ 186
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
21-244 |
3.00e-15 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 76.94 E-value: 3.00e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALperELTLARRQIGMIFQHfNLLSSRTVF 100
Cdd:PLN03232 1252 LHGLSFFVSPSEKVGVVGRTGAGKSSMLNALFRIVELEKGRIMIDDCDVAKF---GLTDLRRVLSIIPQS-PVLFSGTVR 1327
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAfPLEL---AGWSKSQIRARVDELLAL--VGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:PLN03232 1328 FNID-PFSEhndADLWEALERAHIKDVIDRnpFGLDAEVSEGGENFSVGQRQLLSLARALLRRSKILVLDEATASVDVRT 1406
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 176 TRSILSLLKEiNVKlGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSNAKTQLARdFIHST 244
Cdd:PLN03232 1407 DSLIQRTIRE-EFK-SCTMLVIAHRLNTIID-CDKILVLSSGQVLEYDSPQELLSRDTSAFFR-MVHST 1471
|
|
| PTZ00265 |
PTZ00265 |
multidrug resistance protein (mdr1); Provisional |
60-205 |
4.38e-15 |
|
multidrug resistance protein (mdr1); Provisional
Pssm-ID: 240339 [Multi-domain] Cd Length: 1466 Bit Score: 76.61 E-value: 4.38e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 60 GQVIVDGQDLVALPERELtlarRQIGMIFQHFNLLSSRTVFANIAFPLELAgwSKSQIR-----ARVDELLALV--GLEA 132
Cdd:PTZ00265 1277 GKILLDGVDICDYNLKDL----RNLFSIVSQEPMLFNMSIYENIKFGKEDA--TREDVKrackfAAIDEFIESLpnKYDT 1350
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 133 RAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVK 205
Cdd:PTZ00265 1351 NVGPYGKSLSGGQKQRIAIARALLREPKILLLDEATSSLDSNSEKLIEKTIVDIKDKADKTIITIAHRIASIK 1423
|
|
| PRK09700 |
PRK09700 |
D-allose ABC transporter ATP-binding protein AlsA; |
22-221 |
1.34e-14 |
|
D-allose ABC transporter ATP-binding protein AlsA;
Pssm-ID: 182036 [Multi-domain] Cd Length: 510 Bit Score: 74.44 E-value: 1.34e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 22 RDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLValPERELTLARRQIGMIFQH------FNLLS 95
Cdd:PRK09700 280 RDISFSVCRGEILGFAGLVGSGRTELMNCLFGVDKRAGGEIRLNGKDIS--PRSPLDAVKKGMAYITESrrdngfFPNFS 357
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SRTVFAnIAFPLELAGW----------SKSQIRARVDELLALvgleaRAHAYP---SELSGGQKQRVAIARALAPAPKVL 162
Cdd:PRK09700 358 IAQNMA-ISRSLKDGGYkgamglfhevDEQRTAENQRELLAL-----KCHSVNqniTELSGGNQQKVLISKWLCCCPEVI 431
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 163 LCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIE 221
Cdd:PRK09700 432 IFDEPTRGIDVGAKAEIYKVMRQL-ADDGKVILMVSSELPEIITVCDRIAVFCEGRLTQ 489
|
|
| ABCF_EF-3 |
cd03221 |
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is ... |
2-217 |
1.52e-14 |
|
ATP-binding cassette domain of elongation factor 3, subfamily F; Elongation factor 3 (EF-3) is a cytosolic protein required by fungal ribosomes for in vitro protein synthesis and for in vivo growth. EF-3 stimulates the binding of the EF-1: GTP: aa-tRNA ternary complex to the ribosomal A site by facilitated release of the deacylated tRNA from the E site. The reaction requires ATP hydrolysis. EF-3 contains two ATP nucleotide binding sequence (NBS) motifs. NBSI is sufficient for the intrinsic ATPase activity. NBSII is essential for the ribosome-stimulated functions.
Pssm-ID: 213188 [Multi-domain] Cd Length: 144 Bit Score: 69.78 E-value: 1.52e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKGSdavhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDgqdlvalpereltlar 81
Cdd:cd03221 1 IELENLSKTYGGKL----LLKDISLTINPGDRIGLVGRNGAGKSTLLKLIAGELEPDEGIVTWG---------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 rqigmifqhfnllssrtvfaniafplelagwSKSQIrarvdellalvglearahAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:cd03221 61 -------------------------------STVKI------------------GYFEQLSGGEKMRLALAKLLLENPNL 91
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 162 LLCDEATSALDPQTTRSILSLLKEINvklGlTILLITHEMDVVKGICDDVAIISDG 217
Cdd:cd03221 92 LLLDEPTNHLDLESIEALEEALKEYP---G-TVILVSHDRYFLDQVATKIIELEDG 143
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
21-228 |
1.70e-14 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 74.82 E-value: 1.70e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVivdgqdlvalpereltLARRQIGMIFQHFNLLSSrTVF 100
Cdd:PTZ00243 676 LRDVSVSVPRGKLTVVLGATGSGKSTLLQSLLSQFEISEGRV----------------WAERSIAYVPQQAWIMNA-TVR 738
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAF-----PLELAGWSK-SQIRARVDELLAlvGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQ 174
Cdd:PTZ00243 739 GNILFfdeedAARLADAVRvSQLEADLAQLGG--GLETEIGEKGVNLSGGQKARVSLARAVYANRDVYLLDDPLSALDAH 816
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 175 TTRSILS--LLKEINVKlglTILLITHEMDVVKgICDDVAIISDGSLIEQGEVAWF 228
Cdd:PTZ00243 817 VGERVVEecFLGALAGK---TRVLATHQVHVVP-RADYVVALGDGRVEFSGSSADF 868
|
|
| 40850658_otr |
NF000106 |
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit; |
2-225 |
2.09e-14 |
|
oxytetracycline efflux ABC transporter Otr(C) ATP-binding subunit;
Pssm-ID: 411078 [Multi-domain] Cd Length: 351 Bit Score: 73.23 E-value: 2.09e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGKgsdaVHALRDVSLHVPQGKIFGVIGASGAG--KSTLircvnllerPTEgqviVDGQDLVALPERELTL 79
Cdd:NF000106 14 VEVRGLVKHFGE----VKAVDGVDLDVREGTVLGVLGP*GAA**RGAL---------PAH----V*GPDAGRRPWRF*TW 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 A------RRQIG----MIFQHFNLLSSRTVFANIAFPLELagwSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRV 149
Cdd:NF000106 77 CanrralRRTIG*hrpVR*GRRESFSGRENLYMIGR*LDL---SRKDARARADELLERFSLTEAAGRAAAKYSGGMRRRL 153
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:NF000106 154 DLAASMIGRPAVLYLDEPTTGLDPRTRNEVWDEVRSM-VRDGATVLLTTQYMEEAEQLAHELTVIDRGRVIADGKV 228
|
|
| PRK13538 |
PRK13538 |
cytochrome c biogenesis heme-transporting ATPase CcmA; |
22-199 |
5.12e-14 |
|
cytochrome c biogenesis heme-transporting ATPase CcmA;
Pssm-ID: 184125 [Multi-domain] Cd Length: 204 Bit Score: 69.83 E-value: 5.12e-14
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 22 RDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPE---RELTLarrqIGmifqHFNLLSSR- 97
Cdd:PRK13538 18 SGLSFTLNAGELVQIEGPNGAGKTSLLRILAGLARPDAGEVLWQGEPIRRQRDeyhQDLLY----LG----HQPGIKTEl 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAFPLELAGwskSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTR 177
Cdd:PRK13538 90 TALENLRFYQRLHG---PGDDEALWEALAQVGLAGFEDVPVRQLSAGQQRRVALARLWLTRAPLWILDEPFTAIDKQGVA 166
|
170 180
....*....|....*....|..
gi 754651031 178 SILSLLKEiNVKLGLTILLITH 199
Cdd:PRK13538 167 RLEALLAQ-HAEQGGMVILTTH 187
|
|
| CFTR_protein |
TIGR01271 |
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis ... |
4-185 |
1.03e-13 |
|
cystic fibrosis transmembrane conductor regulator (CFTR); The model describes the cystis fibrosis transmembrane conductor regulator (CFTR) in eukaryotes. The principal role of this protein is chloride ion conductance. The protein is predicted to consist of 12 transmembrane domains. Mutations or lesions in the genetic loci have been linked to the aetiology of asthma, bronchiectasis, chronic obstructive pulmonary disease etc. Disease-causing mutations have been studied by 36Cl efflux assays in vitro cell cultures and electrophysiology, all of which point to the impairment of chloride channel stability and not the biosynthetic processing per se. [Transport and binding proteins, Anions]
Pssm-ID: 273530 [Multi-domain] Cd Length: 1490 Bit Score: 72.25 E-value: 1.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTLIRCVnLLERPTEGQVIVDGqdlVALPERELTLARRQ 83
Cdd:TIGR01271 1220 VQGLTAKYTEAGRAV--LQDLSFSVEGGQRVGLLGRTGSGKSTLLSAL-LRLLSTEGEIQIDG---VSWNSVTLQTWRKA 1293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 84 IGMIFQHFNLLSSrTVFANIAfPLElaGWSKSQIRARVDEllalVGLEARAHAYPSEL-----------SGGQKQRVAIA 152
Cdd:TIGR01271 1294 FGVIPQKVFIFSG-TFRKNLD-PYE--QWSDEEIWKVAEE----VGLKSVIEQFPDKLdfvlvdggyvlSNGHKQLMCLA 1365
|
170 180 190
....*....|....*....|....*....|...
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTTRSILSLLKE 185
Cdd:TIGR01271 1366 RSILSKAKILLLDEPSAHLDPVTLQIIRKTLKQ 1398
|
|
| tagH |
PRK13545 |
teichoic acids export protein ATP-binding subunit; Provisional |
9-225 |
1.53e-13 |
|
teichoic acids export protein ATP-binding subunit; Provisional
Pssm-ID: 184130 [Multi-domain] Cd Length: 549 Bit Score: 71.46 E-value: 1.53e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 9 KVYGKGSDAV-------------HALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQ-DLVALPE 74
Cdd:PRK13545 15 KMYNKPFDKLkdlffrskdgeyhYALNNISFEVPEGEIVGIIGLNGSGKSTLSNLIAGVTMPNKGTVDIKGSaALIAISS 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 75 reltlarrqigmifqhfNLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:PRK13545 95 -----------------GLNGQLTGIENIELKGLMMGLTKEKIKEIIPEIIEFADIGKFIYQPVKTYSSGMKSRLGFAIS 157
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:PRK13545 158 VHINPDILVIDEALSVGDQTFTKKCLDKMNEFKEQ-GKTIFFISHSLSQVKSFCTKALWLHYGQVKEYGDI 227
|
|
| PRK13546 |
PRK13546 |
teichoic acids export ABC transporter ATP-binding subunit TagH; |
12-225 |
2.12e-13 |
|
teichoic acids export ABC transporter ATP-binding subunit TagH;
Pssm-ID: 184131 [Multi-domain] Cd Length: 264 Bit Score: 69.46 E-value: 2.12e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 12 GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGqdlvalpereltlarrQIGMIFQHF 91
Cdd:PRK13546 31 KHKNKTFFALDDISLKAYEGDVIGLVGINGSGKSTLSNIIGGSLSPTVGKVDRNG----------------EVSVIAISA 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 NLLSSRTVFANIAFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSAL 171
Cdd:PRK13546 95 GLSGQLTGIENIEFKMLCMGFKRKEIKAMTPKIIEFSELGEFIYQPVKKYSSGMRAKLGFSINITVNPDILVIDEALSVG 174
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 754651031 172 DPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLIEQGEV 225
Cdd:PRK13546 175 DQTFAQKCLDKIYEFK-EQNKTIFFVSHNLGQVRQFCTKIAWIEGGKLKDYGEL 227
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
4-200 |
6.99e-13 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 69.19 E-value: 6.99e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGKGSdavHALRDVSL-HVPQGKIfGVIGASGAGKSTLIRCVNLLERPTEGQvivdgqdlvALPERELTlarr 82
Cdd:TIGR03719 7 MNRVSKVVPPKK---EILKDISLsFFPGAKI-GVLGLNGAGKSTLLRIMAGVDKDFNGE---------ARPQPGIK---- 69
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 qIGMIFQHFNLLSSRTVFANIafplELAGWSKSQIRARVDELLALVG-------------------------------LE 131
Cdd:TIGR03719 70 -VGYLPQEPQLDPTKTVRENV----EEGVAEIKDALDRFNEISAKYAepdadfdklaaeqaelqeiidaadawdldsqLE 144
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 132 ARAHAY--P------SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvklGlTILLITHE 200
Cdd:TIGR03719 145 IAMDALrcPpwdadvTKLSGGERRRVALCRLLLSKPDMLLLDEPTNHLDAESVAWLERHLQEYP---G-TVVAVTHD 217
|
|
| ABCG_PDR_domain1 |
cd03233 |
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette ... |
12-223 |
1.01e-12 |
|
First domain of the pleiotropic drug resistance-like subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide-binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213200 [Multi-domain] Cd Length: 202 Bit Score: 66.13 E-value: 1.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 12 GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPT---EGQVIVDGQDLVALPEReltlARRQIGMIF 88
Cdd:cd03233 14 GKGRSKIPILKDFSGVVKPGEMVLVLGRPGSGCSTLLKALANRTEGNvsvEGDIHYNGIPYKEFAEK----YPGEIIYVS 89
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 89 QHFNLLSSRTVFANIAFPLELagwsksqirarvdellalvgleaRAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEAT 168
Cdd:cd03233 90 EEDVHFPTLTVRETLDFALRC-----------------------KGNEFVRGISGGERKRVSIAEALVSRASVLCWDNST 146
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 169 SALDPQTTRSILSLLKEINVKLGLTILLITHEM-DVVKGICDDVAIISDGSLIEQG 223
Cdd:cd03233 147 RGLDSSTALEILKCIRTMADVLKTTTFVSLYQAsDEIYDLFDKVLVLYEGRQIYYG 202
|
|
| ABC_ABC_ChvD |
TIGR03719 |
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of ... |
2-179 |
1.08e-12 |
|
ATP-binding cassette protein, ChvD family; Members of this protein family have two copies of the ABC transporter ATP-binding cassette, but are found outside the common ABC transporter operon structure that features integral membrane permease proteins and substrate-binding proteins encoded next to the ATP-binding cassette (ABC domain) protein. The member protein ChvD from Agrobacterium tumefaciens was identified as both a candidate to interact with VirB8, based on yeast two-hybrid analysis, and as an apparent regulator of VirG. The general function of this protein family is unknown.
Pssm-ID: 274744 [Multi-domain] Cd Length: 552 Bit Score: 68.81 E-value: 1.08e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsDAVhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDgqDLValpereltlar 81
Cdd:TIGR03719 323 IEAENLTKAFG---DKL-LIDDLSFKLPPGGIVGVIGPNGAGKSTLFRMITGQEQPDSGTIEIG--ETV----------- 385
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 rQIGMIFQ-HFNLLSSRTVFANIAFPLELAGWSKSQIRARvdellALVGL----EARAHAYPSELSGGQKQRVAIARALA 156
Cdd:TIGR03719 386 -KLAYVDQsRDALDPNKTVWEEISGGLDIIKLGKREIPSR-----AYVGRfnfkGSDQQKKVGQLSGGERNRVHLAKTLK 459
|
170 180
....*....|....*....|...
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSI 179
Cdd:TIGR03719 460 SGGNVLLLDEPTNDLDVETLRAL 482
|
|
| PRK15439 |
PRK15439 |
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional |
22-219 |
3.47e-12 |
|
autoinducer 2 ABC transporter ATP-binding protein LsrA; Provisional
Pssm-ID: 185336 [Multi-domain] Cd Length: 510 Bit Score: 67.00 E-value: 3.47e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 22 RDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPerelTLARRQIGMIF-----QHFNLLSS 96
Cdd:PRK15439 280 RNISLEVRAGEILGLAGVVGAGRTELAETLYGLRPARGGRIMLNGKEINALS----TAQRLARGLVYlpedrQSSGLYLD 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAFPL--ELAGWSK-SQIRARVDELLALVGLE-ARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK15439 356 APLAWNVCALThnRRGFWIKpARENAVLERYRRALNIKfNHAEQAARTLSGGNQQKVLIAKCLEASPQLLIVDEPTRGVD 435
|
170 180 190 200
....*....|....*....|....*....|....*....|....*..
gi 754651031 173 PQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:PRK15439 436 VSARNDIYQLIRSI-AAQNVAVLFISSDLEEIEQMADRVLVMHQGEI 481
|
|
| PRK10762 |
PRK10762 |
D-ribose transporter ATP binding protein; Provisional |
21-235 |
4.43e-12 |
|
D-ribose transporter ATP binding protein; Provisional
Pssm-ID: 236755 [Multi-domain] Cd Length: 501 Bit Score: 66.95 E-value: 4.43e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLERpTEGQVIVDGQDLVALPERElTLA---------RRQ----IGM 86
Cdd:PRK10762 268 VNDVSFTLRKGEILGVSGLMGAGRTELMKVLyGALPR-TSGYVTLDGHEVVTRSPQD-GLAngivyisedRKRdglvLGM 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 87 IFQHFNLLSSRTVFANIAFPLElagwsKSQIRARVDELLALVGLEArahayPS------ELSGGQKQRVAIARALAPAPK 160
Cdd:PRK10762 346 SVKENMSLTALRYFSRAGGSLK-----HADEQQAVSDFIRLFNIKT-----PSmeqaigLLSGGNQQKVAIARGLMTRPK 415
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAIISDGSLieQGEvawFFSNAKTQ 235
Cdd:PRK10762 416 VLILDEPTRGVDVGAKKEIYQLINQFK-AEGLSIILVSSEMPEVLGMSDRILVMHEGRI--SGE---FTREQATQ 484
|
|
| araG |
PRK11288 |
L-arabinose ABC transporter ATP-binding protein AraG; |
24-226 |
8.42e-12 |
|
L-arabinose ABC transporter ATP-binding protein AraG;
Pssm-ID: 183077 [Multi-domain] Cd Length: 501 Bit Score: 66.09 E-value: 8.42e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 24 VSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLA--------RRQIGMIFQHF---N 92
Cdd:PRK11288 272 ISFSVRAGEIVGLFGLVGAGRSELMKLLYGATRRTAGQVYLDGKPIDIRSPRDAIRAgimlcpedRKAEGIIPVHSvadN 351
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 93 L-LSSRTVFANIAFPLElAGWSKSQIRARVDELlalvGLEARAHAYP-SELSGGQKQRVAIARALAPAPKVLLCDEATSA 170
Cdd:PRK11288 352 InISARRHHLRAGCLIN-NRWEAENADRFIRSL----NIKTPSREQLiMNLSGGNQQKAILGRWLSEDMKVILLDEPTRG 426
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 171 LDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIeqGEVA 226
Cdd:PRK11288 427 IDVGAKHEIYNVIYEL-AAQGVAVLFVSSDLPEVLGVADRIVVMREGRIA--GELA 479
|
|
| ABCG_PDR_domain2 |
cd03232 |
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding ... |
21-200 |
1.17e-11 |
|
Second domain of the pleiotropic drug resistance-like (PDR) subfamily G of ATP-binding cassette transporters; The pleiotropic drug resistance (PDR) is a well-described phenomenon occurring in fungi and shares several similarities with processes in bacteria and higher eukaryotes. This PDR subfamily represents domain I of its (ABC-IM)2 organization. ABC transporters are a large family of proteins involved in the transport of a wide variety of different compounds including sugars, ions, peptides, and more complex organic molecules. The nucleotide binding domain shows the highest similarity between all members of the family. ABC transporters are a subset of nucleotide hydrolases that contain a signature motif, Q-loop, and H-loop/switch region, in addition to, the Walker A motif/P-loop and Walker B motif commonly found in a number of ATP- and GTP-binding and hydrolyzing proteins.
Pssm-ID: 213199 [Multi-domain] Cd Length: 192 Bit Score: 63.03 E-value: 1.17e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCvnLLERPT----EGQVIVDGQdlvalpERELTLARRqIGMIFQHFNLLSS 96
Cdd:cd03232 23 LNNISGYVKPGTLTALMGESGAGKTTLLDV--LAGRKTagviTGEILINGR------PLDKNFQRS-TGYVEQQDVHSPN 93
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 RTVFANIAFplelagwsksqirarvdellalvglearaHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTT 176
Cdd:cd03232 94 LTVREALRF-----------------------------SALLRGLSVEQRKRLTIGVELAAKPSILFLDEPTSGLDSQAA 144
|
170 180
....*....|....*....|....
gi 754651031 177 RSILSLLKEInVKLGLTILLITHE 200
Cdd:cd03232 145 YNIVRFLKKL-ADSGQAILCTIHQ 167
|
|
| ABC_UvrA |
cd03238 |
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in ... |
18-205 |
1.19e-11 |
|
ATP-binding cassette domain of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213205 [Multi-domain] Cd Length: 176 Bit Score: 62.73 E-value: 1.19e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLirCVNLLERPTEGQVIvdgqDLVALPERELTLarrqigMIfqhfnllssr 97
Cdd:cd03238 8 VHNLQNLDVSIPLNVLVVVTGVSGSGKSTL--VNEGLYASGKARLI----SFLPKFSRNKLI------FI---------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 tvfaniafplelagwskSQIRARVDELLALVGLEARAhaypSELSGGQKQRVAIARALA--PAPKVLLCDEATSALDPQT 175
Cdd:cd03238 66 -----------------DQLQFLIDVGLGYLTLGQKL----STLSGGELQRVKLASELFsePPGTLFILDEPSTGLHQQD 124
|
170 180 190
....*....|....*....|....*....|
gi 754651031 176 TRSILSLLKEInVKLGLTILLITHEMDVVK 205
Cdd:cd03238 125 INQLLEVIKGL-IDLGNTVILIEHNLDVLS 153
|
|
| PTZ00243 |
PTZ00243 |
ABC transporter; Provisional |
21-223 |
1.84e-11 |
|
ABC transporter; Provisional
Pssm-ID: 240327 [Multi-domain] Cd Length: 1560 Bit Score: 65.57 E-value: 1.84e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHfNLLSSRTVF 100
Cdd:PTZ00243 1326 LRGVSFRIAPREKVGIVGRTGSGKSTLLLTFMRMVEVCGGEIRVNGREIGAYGLREL---RRQFSMIPQD-PVLFDGTVR 1401
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANI-----AFP------LELAGwsksqIRARV---DEllalvGLEARAHAYPSELSGGQKQRVAIARA-LAPAPKVLLCD 165
Cdd:PTZ00243 1402 QNVdpfleASSaevwaaLELVG-----LRERVaseSE-----GIDSRVLEGGSNYSVGQRQLMCMARAlLKKGSGFILMD 1471
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 166 EATSALDPQTTRSILSLLkeINVKLGLTILLITHEMDVVKGiCDDVAIISDGSLIEQG 223
Cdd:PTZ00243 1472 EATANIDPALDRQIQATV--MSAFSAYTVITIAHRLHTVAQ-YDKIIVMDHGAVAEMG 1526
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
29-244 |
3.01e-11 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 64.76 E-value: 3.01e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 29 PQGKIfGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFNLLSSRTVF-------- 100
Cdd:PLN03130 1264 PSEKV-GIVGRTGAGKSSMLNALFRIVELERGRILIDGCDISKFGLMDL---RKVLGIIPQAPVLFSGTVRFnldpfneh 1339
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 --ANIAFPLELAGWsKSQIRARVdellalVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:PLN03130 1340 ndADLWESLERAHL-KDVIRRNS------LGLDAEVSEAGENFSVGQRQLLSLARALLRRSKILVLDEATAAVDVRTDAL 1412
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 179 ILSLLKEiNVKlGLTILLITHEMDVVKGiCDDVAIISDGSLIEQGEVAWFFSNAKTQLARdFIHST 244
Cdd:PLN03130 1413 IQKTIRE-EFK-SCTMLIIAHRLNTIID-CDRILVLDAGRVVEFDTPENLLSNEGSAFSK-MVQST 1474
|
|
| PRK13543 |
PRK13543 |
heme ABC exporter ATP-binding protein CcmA; |
27-174 |
5.25e-11 |
|
heme ABC exporter ATP-binding protein CcmA;
Pssm-ID: 184129 [Multi-domain] Cd Length: 214 Bit Score: 61.40 E-value: 5.25e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 27 HVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDlVALPEREltlarRQIGMIFQHFNLLSSRTVFANIAFP 106
Cdd:PRK13543 33 HVDAGEALLVQGDNGAGKTTLLRVLAGLLHVESGQIQIDGKT-ATRGDRS-----RFMAYLGHLPGLKADLSTLENLHFL 106
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 107 LELAGWSKSQIRARVdelLALVGLEARAHAYPSELSGGQKQRVAIARA-LAPAPKVLLcDEATSALDPQ 174
Cdd:PRK13543 107 CGLHGRRAKQMPGSA---LAIVGLAGYEDTLVRQLSAGQKKRLALARLwLSPAPLWLL-DEPYANLDLE 171
|
|
| PRK13549 |
PRK13549 |
xylose transporter ATP-binding subunit; Provisional |
23-219 |
6.50e-11 |
|
xylose transporter ATP-binding subunit; Provisional
Pssm-ID: 184134 [Multi-domain] Cd Length: 506 Bit Score: 63.41 E-value: 6.50e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLERPTEGQVIVDGQDL-VALPERELtlaRRQIGMI---FQHFNLLSSR 97
Cdd:PRK13549 280 DVSFSLRRGEILGIAGLVGAGRTELVQCLfGAYPGRWEGEIFIDGKPVkIRNPQQAI---AQGIAMVpedRKRDGIVPVM 356
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAfpleLAGWSKSQIRARVDELLALVGLE---ARAH---AYP----SELSGGQKQRVAIARALAPAPKVLLCDEA 167
Cdd:PRK13549 357 GVGKNIT----LAALDRFTGGSRIDDAAELKTILesiQRLKvktASPelaiARLSGGNQQKAVLAKCLLLNPKILILDEP 432
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 168 TSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:PRK13549 433 TRGIDVGAKYEIYKLINQL-VQQGVAIIVISSELPEVLGLSDRVLVMHEGKL 483
|
|
| PRK10522 |
PRK10522 |
multidrug transporter membrane component/ATP-binding component; Provisional |
21-239 |
8.62e-11 |
|
multidrug transporter membrane component/ATP-binding component; Provisional
Pssm-ID: 236707 [Multi-domain] Cd Length: 547 Bit Score: 63.07 E-value: 8.62e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGK---------------IFgVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIG 85
Cdd:PRK10522 325 LRNVTFAYQDNGfsvgpinltikrgelLF-LIGGNGSGKSTLAMLLTGLYQPQSGEILLDGKPVTAEQPEDY---RKLFS 400
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 86 MIFQHFNLlssrtvfaniaFPLELAGWSKSQIRARVDELLALVGLEARAHAYPSE-----LSGGQKQRVAIARALAPAPK 160
Cdd:PRK10522 401 AVFTDFHL-----------FDQLLGPEGKPANPALVEKWLERLKMAHKLELEDGRisnlkLSKGQKKRLALLLALAEERD 469
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 161 VLLCDEATSALDPQTTR----SILSLLKEinvkLGLTILLITHemdvvkgicDDVAIISDGSLIE--QGEVAWFFSNAKT 234
Cdd:PRK10522 470 ILLLDEWAADQDPHFRRefyqVLLPLLQE----MGKTIFAISH---------DDHYFIHADRLLEmrNGQLSELTGEERD 536
|
....*
gi 754651031 235 QLARD 239
Cdd:PRK10522 537 AASRD 541
|
|
| xylG |
TIGR02633 |
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose ... |
23-219 |
1.01e-10 |
|
D-xylose ABC transporter, ATP-binding protein; Several bacterial species have enzymes xylose isomerase and xylulokinase enzymes for xylose utilization. Members of this protein family are the ATP-binding cassette (ABC) subunit of the known or predicted high-affinity xylose ABC transporter for xylose import. These genes, which closely resemble other sugar transport ABC transporter genes, typically are encoded near xylose utilization enzymes and regulatory proteins. Note that this form of the transporter contains two copies of the ABC transporter domain (pfam00005). [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 131681 [Multi-domain] Cd Length: 500 Bit Score: 62.53 E-value: 1.01e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCV-NLLERPTEGQVIVDGQDL-VALPERELtlaRRQIGMI---FQHFNLLSSR 97
Cdd:TIGR02633 278 DVSFSLRRGEILGVAGLVGAGRTELVQALfGAYPGKFEGNVFINGKPVdIRNPAQAI---RAGIAMVpedRKRHGIVPIL 354
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIAfpleLAGWSKSQIRARVDE-------LLALVGLEARAhAYP----SELSGGQKQRVAIARALAPAPKVLLCDE 166
Cdd:TIGR02633 355 GVGKNIT----LSVLKSFCFKMRIDAaaelqiiGSAIQRLKVKT-ASPflpiGRLSGGNQQKAVLAKMLLTNPRVLILDE 429
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|...
gi 754651031 167 ATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:TIGR02633 430 PTRGVDVGAKYEIYKLINQL-AQEGVAIIVVSSELAEVLGLSDRVLVIGEGKL 481
|
|
| PRK11147 |
PRK11147 |
ABC transporter ATPase component; Reviewed |
21-200 |
2.07e-10 |
|
ABC transporter ATPase component; Reviewed
Pssm-ID: 236861 [Multi-domain] Cd Length: 635 Bit Score: 61.89 E-value: 2.07e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNllerpteGQVIVDGQDLVAlpERELTLARRQigmifQHFNLLSSRTVF 100
Cdd:PRK11147 19 LDNAELHIEDNERVCLVGRNGAGKSTLMKILN-------GEVLLDDGRIIY--EQDLIVARLQ-----QDPPRNVEGTVY 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPL---------------------------ELA----------GWsksQIRARVDELLALVGLEAraHAYPSELSG 143
Cdd:PRK11147 85 DFVAEGIeeqaeylkryhdishlvetdpseknlnELAklqeqldhhnLW---QLENRINEVLAQLGLDP--DAALSSLSG 159
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*..
gi 754651031 144 GQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINvklGlTILLITHE 200
Cdd:PRK11147 160 GWLRKAALGRALVSNPDVLLLDEPTNHLDIETIEWLEGFLKTFQ---G-SIIFISHD 212
|
|
| ABCC_CFTR2 |
cd03289 |
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator ... |
11-219 |
2.20e-10 |
|
ATP-binding cassette domain 2 of CFTR,subfamily C; The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213256 [Multi-domain] Cd Length: 275 Bit Score: 60.64 E-value: 2.20e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDAVhaLRDVSLHVPQGKIFGVIGASGAGKSTL----IRCVNllerpTEGQVIVDGQDLVALPERELtlaRRQIGM 86
Cdd:cd03289 12 YTEGGNAV--LENISFSISPGQRVGLLGRTGSGKSTLlsafLRLLN-----TEGDIQIDGVSWNSVPLQKW---RKAFGV 81
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 87 IFQHFNLLSSrTVFANIAfPLElaGWSKSQIRARVDEllalVGLEARAHAYPSEL-----------SGGQKQRVAIARAL 155
Cdd:cd03289 82 IPQKVFIFSG-TFRKNLD-PYG--KWSDEEIWKVAEE----VGLKSVIEQFPGQLdfvlvdggcvlSHGHKQLMCLARSV 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 754651031 156 APAPKVLLCDEATSALDPQTTRSILSLLKEINVklGLTILLITHEMDVVKGiCDDVAIISDGSL 219
Cdd:cd03289 154 LSKAKILLLDEPSAHLDPITYQVIRKTLKQAFA--DCTVILSEHRIEAMLE-CQRFLVIEENKV 214
|
|
| PLN03130 |
PLN03130 |
ABC transporter C family member; Provisional |
19-223 |
2.23e-10 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215595 [Multi-domain] Cd Length: 1622 Bit Score: 62.06 E-value: 2.23e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVnLLERPT--EGQVIVDGQdlVA-LPereltlarrQIGMIFqhfnlls 95
Cdd:PLN03130 631 PTLSNINLDVPVGSLVAIVGSTGEGKTSLISAM-LGELPPrsDASVVIRGT--VAyVP---------QVSWIF------- 691
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 96 SRTVFANIAF--PLELAGWSKSQIRARVDELLALvgLEARAHAYPSE----LSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:PLN03130 692 NATVRDNILFgsPFDPERYERAIDVTALQHDLDL--LPGGDLTEIGErgvnISGGQKQRVSMARAVYSNSDVYIFDDPLS 769
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 170 ALDPQTTRSILSllKEINVKL-GLTILLITHEMDVVKGIcDDVAIISDGSLIEQG 223
Cdd:PLN03130 770 ALDAHVGRQVFD--KCIKDELrGKTRVLVTNQLHFLSQV-DRIILVHEGMIKEEG 821
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
2-178 |
2.30e-10 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 61.67 E-value: 2.30e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 2 IKLNGLNKVYGkgsDAVhALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVdGqDLValpereltlar 81
Cdd:PRK11819 325 IEAENLSKSFG---DRL-LIDDLSFSLPPGGIVGIIGPNGAGKSTLFKMITGQEQPDSGTIKI-G-ETV----------- 387
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 rQIGMIFQ-HFNLLSSRTVFANIAFPLELAGWSKSQIRARvdellalvglearahAYPS--------------ELSGGQK 146
Cdd:PRK11819 388 -KLAYVDQsRDALDPNKTVWEEISGGLDIIKVGNREIPSR---------------AYVGrfnfkggdqqkkvgVLSGGER 451
|
170 180 190
....*....|....*....|....*....|..
gi 754651031 147 QRVAIARALAPAPKVLLCDEATSALDPQTTRS 178
Cdd:PRK11819 452 NRLHLAKTLKQGGNVLLLDEPTNDLDVETLRA 483
|
|
| PLN03232 |
PLN03232 |
ABC transporter C family member; Provisional |
21-232 |
1.51e-09 |
|
ABC transporter C family member; Provisional
Pssm-ID: 215640 [Multi-domain] Cd Length: 1495 Bit Score: 59.60 E-value: 1.51e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVnLLERPTEGQVIVDGQDLVA-LPereltlarrQIGMIFqhfnllsSRTV 99
Cdd:PLN03232 633 LSDINLEIPVGSLVAIVGGTGEGKTSLISAM-LGELSHAETSSVVIRGSVAyVP---------QVSWIF-------NATV 695
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 100 FANIAFPLELAG---WSKSQIRARVDELLALVGLE-ARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQT 175
Cdd:PLN03232 696 RENILFGSDFESeryWRAIDVTALQHDLDLLPGRDlTEIGERGVNISGGQKQRVSMARAVYSNSDIYIFDDPLSALDAHV 775
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 176 TRSIL-SLLKEiNVKlGLTILLITHEMDVVKgICDDVAIISDGSLIEQGEVAWFFSNA 232
Cdd:PLN03232 776 AHQVFdSCMKD-ELK-GKTRVLVTNQLHFLP-LMDRIILVSEGMIKEEGTFAELSKSG 830
|
|
| AAA |
smart00382 |
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a ... |
30-220 |
1.77e-09 |
|
ATPases associated with a variety of cellular activities; AAA - ATPases associated with a variety of cellular activities. This profile/alignment only detects a fraction of this vast family. The poorly conserved N-terminal helix is missing from the alignment.
Pssm-ID: 214640 [Multi-domain] Cd Length: 148 Bit Score: 55.84 E-value: 1.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 30 QGKIFGVIGASGAGKSTLIRCV-NLLERPTEGQVIVDGQDLValpereltlarrqigmifqhfnllssrtvfaniafple 108
Cdd:smart00382 1 PGEVILIVGPPGSGKTTLARALaRELGPPGGGVIYIDGEDIL-------------------------------------- 42
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 109 lagwsksqirarvdELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSL-----L 183
Cdd:smart00382 43 --------------EEVLDQLLLIIVGGKKASGSGELRLRLALALARKLKPDVLILDEITSLLDAEQEALLLLLeelrlL 108
|
170 180 190
....*....|....*....|....*....|....*..
gi 754651031 184 KEINVKLGLTILLITHEMDVVKGicDDVAIISDGSLI 220
Cdd:smart00382 109 LLLKSEKNLTVILTTNDEKDLGP--ALLRRRFDRRIV 143
|
|
| PRK11819 |
PRK11819 |
putative ABC transporter ATP-binding protein; Reviewed |
4-199 |
2.45e-09 |
|
putative ABC transporter ATP-binding protein; Reviewed
Pssm-ID: 236992 [Multi-domain] Cd Length: 556 Bit Score: 58.59 E-value: 2.45e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 4 LNGLNKVYGKGSdavHALRDVSLH-VPQGKIfGVIGASGAGKSTLIRCVNLLERPTEGQvivdgqdlvALPERELTlarr 82
Cdd:PRK11819 9 MNRVSKVVPPKK---QILKDISLSfFPGAKI-GVLGLNGAGKSTLLRIMAGVDKEFEGE---------ARPAPGIK---- 71
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 83 qIGMIFQHFNLLSSRTVFANIafplELAGWSKSQIRARVDELLALVG-------------------------------LE 131
Cdd:PRK11819 72 -VGYLPQEPQLDPEKTVRENV----EEGVAEVKAALDRFNEIYAAYAepdadfdalaaeqgelqeiidaadawdldsqLE 146
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 754651031 132 ARAHAY--P------SELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQttrSILSL---LKEINvklGlTILLITH 199
Cdd:PRK11819 147 IAMDALrcPpwdakvTKLSGGERRRVALCRLLLEKPDMLLLDEPTNHLDAE---SVAWLeqfLHDYP---G-TVVAVTH 218
|
|
| ABCC_SUR2 |
cd03288 |
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The ... |
21-221 |
2.54e-09 |
|
ATP-binding cassette domain 2 of the sulfonylurea receptor SUR; The SUR domain 2. The sulfonylurea receptor SUR is an ATP binding cassette (ABC) protein of the ABCC/MRP family. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213255 [Multi-domain] Cd Length: 257 Bit Score: 57.23 E-value: 2.54e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTL----IRCVNLLErpteGQVIVDGQDLVALPERELtlaRRQIGMIFQ------- 89
Cdd:cd03288 37 LKHVKAYIKPGQKVGICGRTGSGKSSLslafFRMVDIFD----GKIVIDGIDISKLPLHTL---RSRLSIILQdpilfsg 109
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 90 --HFNLLSSRTVFANIAF-PLELAgwsksQIRARVDELLAlvGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDE 166
Cdd:cd03288 110 siRFNLDPECKCTDDRLWeALEIA-----QLKNMVKSLPG--GLDAVVTEGGENFSVGQRQLFCLARAFVRKSSILIMDE 182
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 167 ATSALDpQTTRSILSllKEINVKLG-LTILLITHEMDVVKGiCDDVAIISDGSLIE 221
Cdd:cd03288 183 ATASID-MATENILQ--KVVMTAFAdRTVVTIAHRVSTILD-ADLVLVLSRGILVE 234
|
|
| MRP_assoc_pro |
TIGR00957 |
multi drug resistance-associated protein (MRP); This model describes multi drug ... |
21-223 |
4.86e-09 |
|
multi drug resistance-associated protein (MRP); This model describes multi drug resistance-associated protein (MRP) in eukaryotes. The multidrug resistance-associated protein is an integral membrane protein that causes multidrug resistance when overexpressed in mammalian cells. It belongs to ABC transporter superfamily. The protein topology and function was experimentally demonstrated by epitope tagging and immunofluorescence. Insertion of tags in the critical regions associated with drug efflux, abrogated its function. The C-terminal domain seem to highly conserved. [Transport and binding proteins, Other]
Pssm-ID: 188098 [Multi-domain] Cd Length: 1522 Bit Score: 58.03 E-value: 4.86e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdLVALPERELtlarrqigmifqhfnlLSSRTVF 100
Cdd:TIGR00957 654 LNGITFSIPEGALVAVVGQVGCGKSSLLSALLAEMDKVEGHVHMKGS-VAYVPQQAW----------------IQNDSLR 716
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFPLELagwSKSQIRARVDELLALVGLEARAHAYPSE-------LSGGQKQRVAIARALAPAPKVLLCDEATSALDP 173
Cdd:TIGR00957 717 ENILFGKAL---NEKYYQQVLEACALLPDLEILPSGDRTEigekgvnLSGGQKQRVSLARAVYSNADIYLFDDPLSAVDA 793
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 754651031 174 QTTRSIL-SLLKEINVKLGLTILLITHEMDVVKGIcDDVAIISDGSLIEQG 223
Cdd:TIGR00957 794 HVGKHIFeHVIGPEGVLKNKTRILVTHGISYLPQV-DVIIVMSGGKISEMG 843
|
|
| ycf16 |
CHL00131 |
sulfate ABC transporter protein; Validated |
21-225 |
5.70e-09 |
|
sulfate ABC transporter protein; Validated
Pssm-ID: 214372 [Multi-domain] Cd Length: 252 Bit Score: 56.19 E-value: 5.70e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCvnLLERP----TEGQVIVDGQDLVALPEREltlaRRQIGmIFQHFNllss 96
Cdd:CHL00131 23 LKGLNLSINKGEIHAIMGPNGSGKSTLSKV--IAGHPaykiLEGDILFKGESILDLEPEE----RAHLG-IFLAFQ---- 91
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 rtvfaniaFPLELAGWS-------------KSQIRARVDEL---------LALVGLEAR-AHAYPSE-LSGGQKQRVAIA 152
Cdd:CHL00131 92 --------YPIEIPGVSnadflrlaynskrKFQGLPELDPLefleiinekLKLVGMDPSfLSRNVNEgFSGGEKKRNEIL 163
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 754651031 153 RALAPAPKVLLCDEATSALDPQTTRSIlslLKEINVKLGLT--ILLITHE---MDVVKGicDDVAIISDGSLIEQGEV 225
Cdd:CHL00131 164 QMALLDSELAILDETDSGLDIDALKII---AEGINKLMTSEnsIILITHYqrlLDYIKP--DYVHVMQNGKIIKTGDA 236
|
|
| ABCC_SUR1_N |
cd03290 |
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The ... |
21-201 |
7.77e-09 |
|
ATP-binding cassette domain of the sulfonylurea receptor, subfamily C; The SUR domain 1. The sulfonylurea receptor SUR is an ATP transporter of the ABCC/MRP family with tandem ATPase binding domains. Unlike other ABC proteins, it has no intrinsic transport function, neither active nor passive, but associates with the potassium channel proteins Kir6.1 or Kir6.2 to form the ATP-sensitive potassium (K(ATP)) channel. Within the channel complex, SUR serves as a regulatory subunit that fine-tunes the gating of Kir6.x in response to alterations in cellular metabolism. It constitutes a major pharmaceutical target as it binds numerous drugs, K(ATP) channel openers and blockers, capable of up- or down-regulating channel activity.
Pssm-ID: 213257 [Multi-domain] Cd Length: 218 Bit Score: 55.41 E-value: 7.77e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdLVALPERELTLARRQIGMIF--QHFNLLSSrT 98
Cdd:cd03290 17 LSNINIRIPTGQLTMIVGQVGCGKSSLLLAILGEMQTLEGKVHWSNK-NESEPSFEATRSRNRYSVAYaaQKPWLLNA-T 94
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 VFANIAFPlelAGWSKSQIRARVDELLALVGLEARAHAYPSE-------LSGGQKQRVAIARALAPAPKVLLCDEATSAL 171
Cdd:cd03290 95 VEENITFG---SPFNKQRYKAVTDACSLQPDIDLLPFGDQTEigerginLSGGQRQRICVARALYQNTNIVFLDDPFSAL 171
|
170 180 190
....*....|....*....|....*....|....*
gi 754651031 172 DPQTT-----RSILSLLKEINvklgLTILLITHEM 201
Cdd:cd03290 172 DIHLSdhlmqEGILKFLQDDK----RTLVLVTHKL 202
|
|
| ABC_RNaseL_inhibitor_domain2 |
cd03237 |
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
30-172 |
1.18e-08 |
|
The ATP-binding cassette domain 2 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity of more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213204 [Multi-domain] Cd Length: 246 Bit Score: 55.11 E-value: 1.18e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 30 QGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPErelTLARRQIGMIFQhfnLLSSRT-------VFAN 102
Cdd:cd03237 24 ESEVIGILGPNGIGKTTFIKMLAGVLKPDEGDIEIELDTVSYKPQ---YIKADYEGTVRD---LLSSITkdfythpYFKT 97
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 754651031 103 -IAFPLELAGWSKSQIRarvdellalvglearahaypsELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:cd03237 98 eIAKPLQIEQILDREVP---------------------ELSGGELQRVAIAACLSKDADIYLLDEPSAYLD 147
|
|
| ABC_SMC3_euk |
cd03272 |
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of ... |
36-186 |
5.70e-08 |
|
ATP-binding cassette domain of eukaryotic SMC3 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213239 [Multi-domain] Cd Length: 243 Bit Score: 53.03 E-value: 5.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 36 VIGASGAGKSTL---IRCV------NLLERPTEG---------------QVIVDGQD-LVALPERELTLaRRQIGMI--- 87
Cdd:cd03272 28 VVGRNGSGKSNFfaaIRFVlsdeytHLREEQRQAllhegsgpsvmsayvEIIFDNSDnRFPIDKEEVRL-RRTIGLKkde 106
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 88 FQHFNLLSSRTVFANIafpLELAGWSKSQI-----RARVDELLALVGLEARAHaypSELSGGQKQRVAIARALA-----P 157
Cdd:cd03272 107 YFLDKKNVTKNDVMNL---LESAGFSRSNPyyivpQGKINSLTNMKQDEQQEM---QQLSGGQKSLVALALIFAiqkcdP 180
|
170 180
....*....|....*....|....*....
gi 754651031 158 APKVLLcDEATSALDPQTTRSILSLLKEI 186
Cdd:cd03272 181 APFYLF-DEIDAALDAQYRTAVANMIKEL 208
|
|
| PRK10982 |
PRK10982 |
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional |
20-217 |
7.70e-08 |
|
galactose/methyl galaxtoside transporter ATP-binding protein; Provisional
Pssm-ID: 182880 [Multi-domain] Cd Length: 491 Bit Score: 53.58 E-value: 7.70e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 20 ALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERE--------LTLARRQIGmIFQH- 90
Cdd:PRK10982 263 SIRDVSFDLHKGEILGIAGLVGAKRTDIVETLFGIREKSAGTITLHGKKINNHNANEainhgfalVTEERRSTG-IYAYl 341
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 91 ---FNllssrTVFANIAFPLELAGW-SKSQIRARVDELLALVGLEARAHAYP-SELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:PRK10982 342 digFN-----SLISNIRNYKNKVGLlDNSRMKSDTQWVIDSMRVKTPGHRTQiGSLSGGNQQKVIIGRWLLTQPEILMLD 416
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 166 EATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDG 217
Cdd:PRK10982 417 EPTRGIDVGAKFEIYQLIAEL-AKKDKGIIIISSEMPELLGITDRILVMSNG 467
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
36-217 |
3.41e-07 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 51.78 E-value: 3.41e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 36 VIGASGAGKSTLIRCVNLLERPTEGQVIVDgqdlvalpereltlARRQIGMIFQH----FNLLSSRTVFANIAFPlelaG 111
Cdd:PLN03073 540 MVGPNGIGKSTILKLISGELQPSSGTVFRS--------------AKVRMAVFSQHhvdgLDLSSNPLLYMMRCFP----G 601
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 112 WSKSQIRARVDELlALVGLEARAHAYpsELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLkeinVKLG 191
Cdd:PLN03073 602 VPEQKLRAHLGSF-GVTGNLALQPMY--TLSGGQKSRVAFAKITFKKPHILLLDEPSNHLDLDAVEALIQGL----VLFQ 674
|
170 180
....*....|....*....|....*.
gi 754651031 192 LTILLITHEMDVVKGICDDVAIISDG 217
Cdd:PLN03073 675 GGVLMVSHDEHLISGSVDELWVVSEG 700
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
31-219 |
4.43e-07 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 51.43 E-value: 4.43e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 31 GKIFGVIGASGAGKSTLIRCV-NLLErPTEGQVIVD--------GQDLVALPE-----------RELTLA---RRQI--- 84
Cdd:PRK15064 27 GNRYGLIGANGCGKSTFMKILgGDLE-PSAGNVSLDpnerlgklRQDQFAFEEftvldtvimghTELWEVkqeRDRIyal 105
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 85 -------GMifqHFNLLSSRtvFAniafplELAGWSKSqirARVDELLALVGLEARAHAYP-SELSGGQKQRVAIARALA 156
Cdd:PRK15064 106 pemseedGM---KVADLEVK--FA------EMDGYTAE---ARAGELLLGVGIPEEQHYGLmSEVAPGWKLRVLLAQALF 171
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 754651031 157 PAPKVLLCDEATSALDPQTTRSILSLLKEINVklglTILLITHEMDVVKGICDDVAIISDGSL 219
Cdd:PRK15064 172 SNPDILLLDEPTNNLDINTIRWLEDVLNERNS----TMIIISHDRHFLNSVCTHMADLDYGEL 230
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
18-211 |
4.68e-07 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 51.75 E-value: 4.68e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLI---------------RCVNL-LERPTEGQVIVDGQDLVALPERELTLA- 80
Cdd:PRK00635 608 KHNLKDLTISLPLGRLTVVTGVSGSGKSSLIndtlvpaveefieqgFCSNLsIQWGAISRLVHITRDLPGRSQRSIPLTy 687
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 ----------------RRQIGMIFQHFNL------------LSSRTVFAN---IAFPLELAGWSKSQI------RARVDE 123
Cdd:PRK00635 688 ikafddlrelfaeqprSKRLGLTKSHFSFntplgacaecqgLGSITTTDNrtsIPCPSCLGKRFLPQVlevrykGKNIAD 767
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 124 LLALVGLEA------------RAHAY------------P-SELSGGQKQRVAIA-RALAPAPKVLL--CDEATSALDPQT 175
Cdd:PRK00635 768 ILEMTAYEAekffldepsiheKIHALcslgldylplgrPlSSLSGGEIQRLKLAyELLAPSKKPTLyvLDEPTTGLHTHD 847
|
250 260 270
....*....|....*....|....*....|....*.
gi 754651031 176 TRSILSLLKEInVKLGLTILLITHEMDVVKgICDDV 211
Cdd:PRK00635 848 IKALIYVLQSL-THQGHTVVIIEHNMHVVK-VADYV 881
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
9-200 |
6.47e-07 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 51.39 E-value: 6.47e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 9 KVYGKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRCvnLLERPT----EGQVIVDGqdlvaLPERELTLAR--- 81
Cdd:PLN03140 884 KEQGVTEDRLQLLREVTGAFRPGVLTALMGVSGAGKTTLMDV--LAGRKTggyiEGDIRISG-----FPKKQETFARisg 956
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 82 --RQIGMIFQHFNLLSSRTVFANIAFPLELagwSKSQIRARVDELLALVGLEARAHA---YP--SELSGGQKQRVAIARA 154
Cdd:PLN03140 957 ycEQNDIHSPQVTVRESLIYSAFLRLPKEV---SKEEKMMFVDEVMELVELDNLKDAivgLPgvTGLSTEQRKRLTIAVE 1033
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEiNVKLGLTILLITHE 200
Cdd:PLN03140 1034 LVANPSIIFMDEPTSGLDARAAAIVMRTVRN-TVDTGRTVVCTIHQ 1078
|
|
| 3a01203 |
TIGR00954 |
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, ... |
23-199 |
7.25e-07 |
|
Peroxysomal Fatty Acyl CoA Transporter (FAT) Family protein; [Transport and binding proteins, Carbohydrates, organic alcohols, and acids]
Pssm-ID: 273360 [Multi-domain] Cd Length: 659 Bit Score: 50.90 E-value: 7.25e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVN--------LLERPTEGQvivdgqdLVALPERE-LTLA--RRQIgmifqhf 91
Cdd:TIGR00954 470 SLSFEVPSGNNLLICGPNGCGKSSLFRILGelwpvyggRLTKPAKGK-------LFYVPQRPyMTLGtlRDQI------- 535
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 nllssrtVFANIAFPLELAGWSKSQIRARVDE------LLALVGLEARAHaYPSELSGGQKQRVAIARALAPAPKVLLCD 165
Cdd:TIGR00954 536 -------IYPDSSEDMKRRGLSDKDLEQILDNvqlthiLEREGGWSAVQD-WMDVLSGGEKQRIAMARLFYHKPQFAILD 607
|
170 180 190
....*....|....*....|....*....|....
gi 754651031 166 EATSALDPQTTRSILSLLKEInvklGLTILLITH 199
Cdd:TIGR00954 608 ECTSAVSVDVEGYMYRLCREF----GITLFSVSH 637
|
|
| ABC_UvrA_II |
cd03271 |
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair ... |
18-209 |
7.35e-07 |
|
ATP-binding cassette domain II of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213238 [Multi-domain] Cd Length: 261 Bit Score: 49.92 E-value: 7.35e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLI------RCVNLLERPTE--------------GQVIVDGQDLVALPERE- 76
Cdd:cd03271 8 ENNLKNIDVDIPLGVLTCVTGVSGSGKSSLIndtlypALARRLHLKKEqpgnhdrieglehiDKVIVIDQSPIGRTPRSn 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 77 ---LTLARRQIGMIF------QHFN--LLSSRTVFANIAFPLELAGW-------SKSQIRARVDeLLALVGLEARAHAYP 138
Cdd:cd03271 88 patYTGVFDEIRELFcevckgKRYNreTLEVRYKGKSIADVLDMTVEealeffeNIPKIARKLQ-TLCDVGLGYIKLGQP 166
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 139 S-ELSGGQKQRVAIARAL---APAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKgICD 209
Cdd:cd03271 167 AtTLSGGEAQRIKLAKELskrSTGKTLYILDEPTTGLHFHDVKKLLEVLQRL-VDKGNTVVVIEHNLDVIK-CAD 239
|
|
| PLN03211 |
PLN03211 |
ABC transporter G-25; Provisional |
31-217 |
7.49e-07 |
|
ABC transporter G-25; Provisional
Pssm-ID: 215634 [Multi-domain] Cd Length: 659 Bit Score: 50.65 E-value: 7.49e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 31 GKIFGVIGASGAGKSTLIRCV--NLLERPTEGQVIVDGQDLvALPERELTLARRQIGMIFQHFNLLSSRTVFANIAFPLE 108
Cdd:PLN03211 94 GEILAVLGPSGSGKSTLLNALagRIQGNNFTGTILANNRKP-TKQILKRTGFVTQDDILYPHLTVRETLVFCSLLRLPKS 172
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 109 LAGWSKSQIRARVDELLALVGLEAR--AHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEI 186
Cdd:PLN03211 173 LTKQEKILVAESVISELGLTKCENTiiGNSFIRGISGGERKRVSIAHEMLINPSLLILDEPTSGLDATAAYRLVLTLGSL 252
|
170 180 190
....*....|....*....|....*....|..
gi 754651031 187 NVKlGLTILLITHE-MDVVKGICDDVAIISDG 217
Cdd:PLN03211 253 AQK-GKTIVTSMHQpSSRVYQMFDSVLVLSEG 283
|
|
| ABC_UvrA_I |
cd03270 |
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair ... |
18-225 |
7.64e-07 |
|
ATP-binding cassette domain I of the excision repair protein UvrA; Nucleotide excision repair in eubacteria is a process that repairs DNA damage by the removal of a 12-13-mer oligonucleotide containing the lesion. Recognition and cleavage of the damaged DNA is a multistep ATP-dependent reaction that requires the UvrA, UvrB, and UvrC proteins. Both UvrA and UvrB are ATPases, with UvrA having two ATP binding sites, which have the characteristic signature of the family of ABC proteins, and UvrB having one ATP binding site that is structurally related to that of helicases.
Pssm-ID: 213237 [Multi-domain] Cd Length: 226 Bit Score: 49.56 E-value: 7.64e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 18 VHALRDVSLHVPQGKIFGVIGASGAGKSTLI----------RCVNLLE---RPTEGQVIVDGQDLV-----ALPERELTL 79
Cdd:cd03270 8 EHNLKNVDVDIPRNKLVVITGVSGSGKSSLAfdtiyaegqrRYVESLSayaRQFLGQMDKPDVDSIeglspAIAIDQKTT 87
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 80 A---RRQIGMIFQHFNLLssRTVFANIAfplelagwsksqIRARVDELLAlVGLEaraHAYPSE----LSGGQKQRVAIA 152
Cdd:cd03270 88 SrnpRSTVGTVTEIYDYL--RLLFARVG------------IRERLGFLVD-VGLG---YLTLSRsaptLSGGEAQRIRLA 149
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 153 RALAPAPKVLL--CDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKgICDDVAIISDGSLIEQGEV 225
Cdd:cd03270 150 TQIGSGLTGVLyvLDEPSIGLHPRDNDRLIETLKRLR-DLGNTVLVVEHDEDTIR-AADHVIDIGPGAGVHGGEI 222
|
|
| PRK13541 |
PRK13541 |
cytochrome c biogenesis protein CcmA; Provisional |
38-205 |
1.62e-06 |
|
cytochrome c biogenesis protein CcmA; Provisional
Pssm-ID: 184128 [Multi-domain] Cd Length: 195 Bit Score: 47.94 E-value: 1.62e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 38 GASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELTLARRQIGmifqhfnLLSSRTVFANIAFplelagWSKsqI 117
Cdd:PRK13541 33 GANGCGKSSLLRMIAGIMQPSSGNIYYKNCNINNIAKPYCTYIGHNLG-------LKLEMTVFENLKF------WSE--I 97
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 118 RARVDELLALVGLeARAHAYPSE----LSGGQKQRVAIARALAPAPKVLLCDEATSALDPQtTRSILSLLKEINVKLGLT 193
Cdd:PRK13541 98 YNSAETLYAAIHY-FKLHDLLDEkcysLSSGMQKIVAIARLIACQSDLWLLDEVETNLSKE-NRDLLNNLIVMKANSGGI 175
|
170
....*....|..
gi 754651031 194 ILLITHEMDVVK 205
Cdd:PRK13541 176 VLLSSHLESSIK 187
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
25-224 |
1.77e-06 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 49.63 E-value: 1.77e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 25 SLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQDLVALPERELtlaRRQIGMIFQHFN--LLSSRTvfan 102
Cdd:PRK10938 23 SLTLNAGDSWAFVGANGSGKSALARALAGELPLLSGERQSQFSHITRLSFEQL---QKLVSDEWQRNNtdMLSPGE---- 95
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 103 iafplELAGWSKSQI-------RARVDELLALVGLEA---RAHAYpseLSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK10938 96 -----DDTGRTTAEIiqdevkdPARCEQLAQQFGITAlldRRFKY---LSTGETRKTLLCQALMSEPDLLILDEPFDGLD 167
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 173 PQTTRSILSLLKEINVKlGLTILLITHEMDVVKGICDDVAIISDGSLIEQGE 224
Cdd:PRK10938 168 VASRQQLAELLASLHQS-GITLVLVLNRFDEIPDFVQFAGVLADCTLAETGE 218
|
|
| 3a01205 |
TIGR00956 |
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other] |
21-223 |
3.70e-06 |
|
Pleiotropic Drug Resistance (PDR) Family protein; [Transport and binding proteins, Other]
Pssm-ID: 273362 [Multi-domain] Cd Length: 1394 Bit Score: 48.95 E-value: 3.70e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNL----LERPTEGQVIVDGQDLVALpERELTLARRQIGMIFQHFNLLss 96
Cdd:TIGR00956 77 LKPMDGLIKPGELTVVLGRPGSGCSTLLKTIASntdgFHIGVEGVITYDGITPEEI-KKHYRGDVVYNAETDVHFPHL-- 153
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 97 rTVFANIAFPLELA-------GWSKSQIRARVDEL-LALVGLearAHAYPSE--------LSGGQKQRVAIARALAPAPK 160
Cdd:TIGR00956 154 -TVGETLDFAARCKtpqnrpdGVSREEYAKHIADVyMATYGL---SHTRNTKvgndfvrgVSGGERKRVSIAEASLGGAK 229
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHE--MDVVKgICDDVAIISDGSLIEQG 223
Cdd:TIGR00956 230 IQCWDNATRGLDSATALEFIRALKTSANILDTTPLVAIYQcsQDAYE-LFDKVIVLYEGYQIYFG 293
|
|
| ABC_Class2 |
cd03227 |
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems ... |
19-205 |
8.02e-06 |
|
ATP-binding cassette domain of non-transporter proteins; ABC-type Class 2 contains systems involved in cellular processes other than transport. These families are characterized by the fact that the ABC subunit is made up of duplicated, fused ABC modules (ABC2). No known transmembrane proteins or domains are associated with these proteins.
Pssm-ID: 213194 [Multi-domain] Cd Length: 162 Bit Score: 45.43 E-value: 8.02e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 19 HALRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLErptegqvivdGQDLVALPERELTLARRQIGMIFQHFNLLSSRt 98
Cdd:cd03227 9 SYFVPNDVTFGEGSLTIITGPNGSGKSTILDAIGLAL----------GGAQSATRRRSGVKAGCIVAAVSAELIFTRLQ- 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 99 vfaniafplelagwsksqirarvdellalvglearahaypseLSGGQKQRVAIARALA-----PAPKVLLcDEATSALDP 173
Cdd:cd03227 78 ------------------------------------------LSGGEKELSALALILAlaslkPRPLYIL-DEIDRGLDP 114
|
170 180 190
....*....|....*....|....*....|..
gi 754651031 174 QTTRSILSLLKEINVKlGLTILLITHEMDVVK 205
Cdd:cd03227 115 RDGQALAEAILEHLVK-GAQVIVITHLPELAE 145
|
|
| ABCC_CFTR1 |
cd03291 |
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The ... |
21-218 |
9.53e-06 |
|
ATP-binding cassette domain of the cystic fibrosis transmembrane regulator, subfamily C; The CFTR subfamily domain 1. The cystic fibrosis transmembrane regulator (CFTR), the product of the gene mutated in patients with cystic fibrosis, has adapted the ABC transporter structural motif to form a tightly regulated anion channel at the apical surface of many epithelia. Use of the term assembly of a functional ion channel implies the coming together of subunits, or at least smaller not-yet functional components of the active whole. In fact, on the basis of current knowledge only the CFTR polypeptide itself is required to form an ATP- and protein kinase A-dependent low-conductance chloride channel of the type present in the apical membrane of many epithelial cells. CFTR displays the typical organization (IM-ABC)2 and carries a characteristic hydrophilic R-domain that separates IM1-ABC1 from IM2-ABC2.
Pssm-ID: 213258 [Multi-domain] Cd Length: 282 Bit Score: 46.77 E-value: 9.53e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLERPTEGQVIVDGQdlvalpereltlarrqIGMIFQhFNLLSSRTVF 100
Cdd:cd03291 53 LKNINLKIEKGEMLAITGSTGSGKTSLLMLILGELEPSEGKIKHSGR----------------ISFSSQ-FSWIMPGTIK 115
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 101 ANIAFplelaGWSKSQIRARvdELLALVGLEARAHAYPSE-----------LSGGQKQRVAIARALAPAPKVLLCDEATS 169
Cdd:cd03291 116 ENIIF-----GVSYDEYRYK--SVVKACQLEEDITKFPEKdntvlgeggitLSGGQRARISLARAVYKDADLYLLDSPFG 188
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|.
gi 754651031 170 ALDPQTTRSILS--LLKEINVKlglTILLITHEMDVVKgICDDVAIISDGS 218
Cdd:cd03291 189 YLDVFTEKEIFEscVCKLMANK---TRILVTSKMEHLK-KADKILILHEGS 235
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
15-172 |
1.08e-05 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 47.09 E-value: 1.08e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 15 SDAVHALRDVSLHVPQGKIF-----GVIGASGAGKSTLIRCVNLLERPTEGQVivDGQDLVA------LPERELT---LA 80
Cdd:COG1245 345 PDLTKSYGGFSLEVEGGEIRegevlGIVGPNGIGKTTFAKILAGVLKPDEGEV--DEDLKISykpqyiSPDYDGTveeFL 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 81 RRQIGMIFqhfnllSSRTVFANIAFPLELagwsksqirarvDELLalvglearaHAYPSELSGGQKQRVAIARALAPAPK 160
Cdd:COG1245 423 RSANTDDF------GSSYYKTEIIKPLGL------------EKLL---------DKNVKDLSGGELQRVAIAACLSRDAD 475
|
170
....*....|..
gi 754651031 161 VLLCDEATSALD 172
Cdd:COG1245 476 LYLLDEPSAHLD 487
|
|
| Rli1 |
COG1245 |
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ... |
25-172 |
1.16e-05 |
|
Translation initiation factor RLI1, contains Fe-S and AAA+ ATPase domains [Translation, ribosomal structure and biogenesis];
Pssm-ID: 440858 [Multi-domain] Cd Length: 592 Bit Score: 47.09 E-value: 1.16e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 25 SLHVPQ-GKIFGVIGASGAGKSTLIRCV------NL--LERPTEGQVIVD---G---QD-LVALPERELTLARR--QIGM 86
Cdd:COG1245 92 GLPVPKkGKVTGILGPNGIGKSTALKILsgelkpNLgdYDEEPSWDEVLKrfrGtelQDyFKKLANGEIKVAHKpqYVDL 171
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 87 IFQHFN-----LLSsrtvfaniafplelagwsKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKV 161
Cdd:COG1245 172 IPKVFKgtvreLLE------------------KVDERGKLDELAEKLGLENILDRDISELSGGELQRVAIAAALLRDADF 233
|
170
....*....|.
gi 754651031 162 LLCDEATSALD 172
Cdd:COG1245 234 YFFDEPSSYLD 244
|
|
| PLN03073 |
PLN03073 |
ABC transporter F family; Provisional |
23-211 |
1.47e-05 |
|
ABC transporter F family; Provisional
Pssm-ID: 215558 [Multi-domain] Cd Length: 718 Bit Score: 46.78 E-value: 1.47e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 23 DVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLE---RPTEGQVI-----VDGQDLVAL-----PERELTLARRQIGMIFQ 89
Cdd:PLN03073 195 DASVTLAFGRHYGLVGRNGTGKTTFLRYMAMHAidgIPKNCQILhveqeVVGDDTTALqcvlnTDIERTQLLEEEAQLVA 274
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 90 HFNLLSSRTVFANIAFPLElAGWSKSQIRARVDELLALVGL------EARAHA------YPSEL--------SGGQKQRV 149
Cdd:PLN03073 275 QQRELEFETETGKGKGANK-DGVDKDAVSQRLEEIYKRLELidaytaEARAASilaglsFTPEMqvkatktfSGGWRMRI 353
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|..
gi 754651031 150 AIARALAPAPKVLLCDEATSALDPQTTRSILSLLkeinVKLGLTILLITHEMDVVKGICDDV 211
Cdd:PLN03073 354 ALARALFIEPDLLLLDEPTNHLDLHAVLWLETYL----LKWPKTFIVVSHAREFLNTVVTDI 411
|
|
| ABC_RNaseL_inhibitor_domain1 |
cd03236 |
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI) ... |
11-214 |
1.78e-05 |
|
The ATP-binding cassette domain 1 of RNase L inhibitor; The ABC ATPase, RNase L inhibitor (RLI), is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI s are not transport proteins and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLIs have an N-terminal Fe-S domain and two nucleotide binding domains which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213203 [Multi-domain] Cd Length: 255 Bit Score: 45.44 E-value: 1.78e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 11 YGKGSDAVHALRdvslhVPQ-GKIFGVIGASGAGKSTLIRCV------NL--LERPTEGQVIVD---GQDL----VALPE 74
Cdd:cd03236 10 YGPNSFKLHRLP-----VPReGQVLGLVGPNGIGKSTALKILagklkpNLgkFDDPPDWDEILDefrGSELqnyfTKLLE 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 75 RELTLARRQigmifQHFNLLSsRTVFANIAFPLElagwsKSQIRARVDELLALVGLEARAHAYPSELSGGQKQRVAIARA 154
Cdd:cd03236 85 GDVKVIVKP-----QYVDLIP-KAVKGKVGELLK-----KKDERGKLDELVDQLELRHVLDRNIDQLSGGELQRVAIAAA 153
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 155 LAPAPKVLLCDEATSALDPQTTRSILSLLKEINvKLGLTILLITHEMDVVKGICDDVAII 214
Cdd:cd03236 154 LARDADFYFFDEPSSYLDIKQRLNAARLIRELA-EDDNYVLVVEHDLAVLDYLSDYIHCL 212
|
|
| SbcC_Walker_B |
pfam13558 |
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from ... |
139-185 |
5.43e-05 |
|
SbcC/RAD50-like, Walker B motif; This entry represents the Walker B domain of RAD50 from eukaryotes and the prokaryotic homolog SbcCD complex subunit C. RAD50-ATPase forms a complex with Mre11-nuclease that detects and processes diverse and obstructed DNA ends. This domain is separated of the Walker A domain by a long coiled-coil domain and forms the nucleotide-binding domain (NBD) when the coiled coils fold back on themselves and bring together Walker A and B domains. Two RAD50-NBDs forms heterotetramers with a Mre11 nuclease dimer that assemble as catalytic head module that binds and cleaves DNA in an ATP-dependent reaction. Through secondary structural analysis, it has been suggested that there is a wide structural conservation in the Rad50/SMC protein family as seen in structural similarities between RAD50's hook and ABC-ATPase MukB's elbow region.
Pssm-ID: 463921 [Multi-domain] Cd Length: 90 Bit Score: 41.45 E-value: 5.43e-05
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 139 SELSGGQKQR---VAIARALA----------PAPKVLLCDEATSALDPQTTRSILSLLKE 185
Cdd:pfam13558 31 GGLSGGEKQLlayLPLAAALAaqygsaegrpPAPRLVFLDEAFAKLDEENIRTALELLRA 90
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
123-205 |
6.58e-05 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 44.62 E-value: 6.58e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 123 ELLALVGLEARAHAYPS-ELSGGQKQRVAIARAL---APAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLIT 198
Cdd:TIGR00630 811 QTLCDVGLGYIRLGQPAtTLSGGEAQRIKLAKELskrSTGRTLYILDEPTTGLHFDDIKKLLEVLQRL-VDKGNTVVVIE 889
|
....*..
gi 754651031 199 HEMDVVK 205
Cdd:TIGR00630 890 HNLDVIK 896
|
|
| GguA |
NF040905 |
sugar ABC transporter ATP-binding protein; |
21-226 |
9.91e-05 |
|
sugar ABC transporter ATP-binding protein;
Pssm-ID: 468840 [Multi-domain] Cd Length: 500 Bit Score: 44.01 E-value: 9.91e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCV--NLLERPTEGQVIVDGQDLVALPERE--------LTLARRQIGMIFQ- 89
Cdd:NF040905 276 VDDVSLNVRRGEIVGIAGLMGAGRTELAMSVfgRSYGRNISGTVFKDGKEVDVSTVSDaidaglayVTEDRKGYGLNLId 355
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 90 ---------HFNLLSSRTVFANIAfPLELAGWSKSQIRARVDELLALVGlearahaypsELSGGQKQRVAIARALAPAPK 160
Cdd:NF040905 356 dikrnitlaNLGKVSRRGVIDENE-EIKVAEEYRKKMNIKTPSVFQKVG----------NLSGGNQQKVVLSKWLFTDPD 424
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 754651031 161 VLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVKGICDDVAIISDGSLIeqGEVA 226
Cdd:NF040905 425 VLILDEPTRGIDVGAKYEIYTIINEL-AAEGKGVIVISSELPELLGMCDRIYVMNEGRIT--GELP 487
|
|
| PLN03140 |
PLN03140 |
ABC transporter G family member; Provisional |
141-223 |
1.06e-04 |
|
ABC transporter G family member; Provisional
Pssm-ID: 215599 [Multi-domain] Cd Length: 1470 Bit Score: 44.07 E-value: 1.06e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 141 LSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLIT------HEMDVVkgicDDVAII 214
Cdd:PLN03140 337 ISGGQKKRVTTGEMIVGPTKTLFMDEISTGLDSSTTYQIVKCLQQI-VHLTEATVLMSllqpapETFDLF----DDIILL 411
|
....*....
gi 754651031 215 SDGSLIEQG 223
Cdd:PLN03140 412 SEGQIVYQG 420
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
141-258 |
2.28e-04 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 43.28 E-value: 2.28e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 141 LSGGQKQRVAIARALAP--APKVLLCDEATSALDPQTTRSILSLLKEINVKlGLTILLITHEMDVVKgICDDVAIISDGS 218
Cdd:PRK00635 477 LSGGEQERTALAKHLGAelIGITYILDEPSIGLHPQDTHKLINVIKKLRDQ-GNTVLLVEHDEQMIS-LADRIIDIGPGA 554
|
90 100 110 120
....*....|....*....|....*....|....*....|....*
gi 754651031 219 LIEQGEVAWF-----FSNAKTQLARDFIHSTIHLEVPQEYQDRLS 258
Cdd:PRK00635 555 GIFGGEVLFNgspreFLAKSDSLTAKYLRQELTIPIPEKRTNSLG 599
|
|
| PRK10938 |
PRK10938 |
putative molybdenum transport ATP-binding protein ModF; Provisional |
21-173 |
2.73e-04 |
|
putative molybdenum transport ATP-binding protein ModF; Provisional
Pssm-ID: 182852 [Multi-domain] Cd Length: 490 Bit Score: 42.69 E-value: 2.73e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRcvnllerptegqvIVDGQDlvalPE---RELTLARRQIGM------IFQHF 91
Cdd:PRK10938 276 LHNLSWQVNPGEHWQIVGPNGAGKSTLLS-------------LITGDH----PQgysNDLTLFGRRRGSgetiwdIKKHI 338
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 92 NLLSS------------RTVFaniafpleLAGWSKS---------QIRARVDELLALVGLEAR-AHAYPSELSGGQKQRV 149
Cdd:PRK10938 339 GYVSSslhldyrvstsvRNVI--------LSGFFDSigiyqavsdRQQKLAQQWLDILGIDKRtADAPFHSLSWGQQRLA 410
|
170 180
....*....|....*....|....
gi 754651031 150 AIARALAPAPKVLLCDEATSALDP 173
Cdd:PRK10938 411 LIVRALVKHPTLLILDEPLQGLDP 434
|
|
| PRK13409 |
PRK13409 |
ribosome biogenesis/translation initiation ATPase RLI; |
118-172 |
3.26e-04 |
|
ribosome biogenesis/translation initiation ATPase RLI;
Pssm-ID: 184037 [Multi-domain] Cd Length: 590 Bit Score: 42.49 E-value: 3.26e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 118 RARVDELLALVGLEARAHAYPSELSGGQKQRVAIARALAPAPKVLLCDEATSALD 172
Cdd:PRK13409 190 RGKLDEVVERLGLENILDRDISELSGGELQRVAIAAALLRDADFYFFDEPTSYLD 244
|
|
| SbcC |
COG0419 |
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair]; |
33-199 |
3.58e-04 |
|
DNA repair exonuclease SbcCD ATPase subunit [Replication, recombination and repair];
Pssm-ID: 440188 [Multi-domain] Cd Length: 204 Bit Score: 41.15 E-value: 3.58e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 33 IFGVIGASGAGKSTLIRCVNLL-------ERPTEGQVIVDGQD------LVALPERELTLARRQiGMIFQHFNLLSS--R 97
Cdd:COG0419 25 LNLIVGPNGAGKSTILEAIRYAlygkarsRSKLRSDLINVGSEeasvelEFEHGGKRYRIERRQ-GEFAEFLEAKPSerK 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 TVFANIaFPLELAGWS-------KSQIRARVDELLALVGLEARAHAYPSE------LSGGQKQRVAIARALApapkvLLC 164
Cdd:COG0419 104 EALKRL-LGLEIYEELkerlkelEEALESALEELAELQKLKQEILAQLSGldpietLSGGERLRLALADLLS-----LIL 177
|
170 180 190
....*....|....*....|....*....|....*
gi 754651031 165 DeaTSALDPQTTRSILSLLKEINVklgltillITH 199
Cdd:COG0419 178 D--FGSLDEERLERLLDALEELAI--------ITH 202
|
|
| ABC_Rad50 |
cd03240 |
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ... |
33-205 |
6.61e-04 |
|
ATP-binding cassette domain of Rad50; The catalytic domains of Rad50 are similar to the ATP-binding cassette of ABC transporters, but are not associated with membrane-spanning domains. The conserved ATP-binding motifs common to Rad50 and the ABC transporter family include the Walker A and Walker B motifs, the Q loop, a histidine residue in the switch region, a D-loop, and a conserved LSGG sequence. This conserved sequence, LSGG, is the most specific and characteristic motif of this family and is thus known as the ABC signature sequence.
Pssm-ID: 213207 [Multi-domain] Cd Length: 204 Bit Score: 40.28 E-value: 6.61e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 33 IFGVIGASGAGKSTLIRCVNLL---ERPTEGQVIVDGQDLVALPEReltlaRRQIGMIFQHFN---LLSSRT--VFANIA 104
Cdd:cd03240 24 LTLIVGQNGAGKTTIIEALKYAltgELPPNSKGGAHDPKLIREGEV-----RAQVKLAFENANgkkYTITRSlaILENVI 98
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 105 FplelagwsksqirARVDELLALVGLEarahayPSELSGGQKQ------RVAIARALAPAPKVLLCDEATSALDPQTTR- 177
Cdd:cd03240 99 F-------------CHQGESNWPLLDM------RGRCSGGEKVlasliiRLALAETFGSNCGILALDEPTTNLDEENIEe 159
|
170 180
....*....|....*....|....*...
gi 754651031 178 SILSLLKEINVKLGLTILLITHEMDVVK 205
Cdd:cd03240 160 SLAEIIEERKSQKNFQLIVITHDEELVD 187
|
|
| ABC_SMC2_euk |
cd03273 |
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of ... |
139-185 |
1.17e-03 |
|
ATP-binding cassette domain of eukaryotic SMC2 proteins; The structural maintenance of chromosomes (SMC) proteins are large (approximately 110 to 170 kDa), and each is arranged into five recognizable domains. Amino-acid sequence homology of SMC proteins between species is largely confined to the amino- and carboxy-terminal globular domains. The amino-terminal domain contains a 'Walker A' nucleotide-binding domain (GxxGxGKS/T, in the single-letter amino-acid code), which by mutational studies has been shown to be essential in several proteins. The carboxy-terminal domain contains a sequence (the DA-box) that resembles a 'Walker B' motif, and a motif with homology to the signature sequence of the ATP-binding cassette (ABC) family of ATPases. The sequence homology within the carboxy-terminal domain is relatively high within the SMC1-SMC4 group, whereas SMC5 and SMC6 show some divergence in both of these sequences. In eukaryotic cells, the proteins are found as heterodimers of SMC1 paired with SMC3, SMC2 with SMC4, and SMC5 with SMC6 (formerly known as Rad18).
Pssm-ID: 213240 [Multi-domain] Cd Length: 251 Bit Score: 39.97 E-value: 1.17e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 139 SELSGGQKQRVAIARALA-----PAPKVLLcDEATSALDPQTTRSILSLLKE 185
Cdd:cd03273 165 TELSGGQRSLVALSLILAlllfkPAPMYIL-DEVDAALDLSHTQNIGRMIKT 215
|
|
| PRK15064 |
PRK15064 |
ABC transporter ATP-binding protein; Provisional |
12-62 |
1.53e-03 |
|
ABC transporter ATP-binding protein; Provisional
Pssm-ID: 237894 [Multi-domain] Cd Length: 530 Bit Score: 40.26 E-value: 1.53e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|..
gi 754651031 12 GKGSDAVHALRDVSLHVPQGKIFGVIGASGAGKSTLIRC-VNLLErPTEGQV 62
Cdd:PRK15064 326 TKGFDNGPLFKNLNLLLEAGERLAIIGENGVGKTTLLRTlVGELE-PDSGTV 376
|
|
| SMC_N |
pfam02463 |
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The ... |
127-185 |
2.06e-03 |
|
RecF/RecN/SMC N terminal domain; This domain is found at the N terminus of SMC proteins. The SMC (structural maintenance of chromosomes) superfamily proteins have ATP-binding domains at the N- and C-termini, and two extended coiled-coil domains separated by a hinge in the middle. The eukaryotic SMC proteins form two kind of heterodimers: the SMC1/SMC3 and the SMC2/SMC4 types. These heterodimers constitute an essential part of higher order complexes, which are involved in chromatin and DNA dynamics. This family also includes the RecF and RecN proteins that are involved in DNA metabolism and recombination.
Pssm-ID: 426784 [Multi-domain] Cd Length: 1161 Bit Score: 39.95 E-value: 2.06e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 127 LVGLEARAHA------YPSELSGGQKQRVAIARALA-----PAPKVLLcDEATSALDPQTTRSILSLLKE 185
Cdd:pfam02463 1058 SGGIEISARPpgkgvkNLDLLSGGEKTLVALALIFAiqkykPAPFYLL-DEIDAALDDQNVSRVANLLKE 1126
|
|
| uvra |
TIGR00630 |
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of ... |
1-48 |
2.95e-03 |
|
excinuclease ABC, A subunit; This family is a member of the ABC transporter superfamily of proteins of which all members for which functions are known except the UvrA proteins are involved in the transport of material through membranes. UvrA orthologs are involved in the recognition of DNA damage as a step in nucleotide excision repair. This family is based on the phylogenomic analysis of JA Eisen (1999, Ph.D. Thesis, Stanford University). [DNA metabolism, DNA replication, recombination, and repair]
Pssm-ID: 273184 [Multi-domain] Cd Length: 925 Bit Score: 39.61 E-value: 2.95e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*...
gi 754651031 1 MIKLNGLNKvygkgsdavHALRDVSLHVPQGKIFGVIGASGAGKSTLI 48
Cdd:TIGR00630 613 FLTLKGARE---------NNLKNITVSIPLGLFTCITGVSGSGKSTLI 651
|
|
| PRK00635 |
PRK00635 |
excinuclease ABC subunit A; Provisional |
139-205 |
3.90e-03 |
|
excinuclease ABC subunit A; Provisional
Pssm-ID: 234806 [Multi-domain] Cd Length: 1809 Bit Score: 39.43 E-value: 3.90e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 139 SELSGGQKQRVAIARALAPAPK---VLLCDEATSALDPQTTRSILSLLKEInVKLGLTILLITHEMDVVK 205
Cdd:PRK00635 1698 SSLSLSEKIAIKIAKFLYLPPKhptLFLLDEIATSLDNQQKSALLVQLRTL-VSLGHSVIYIDHDPALLK 1766
|
|
| ABC_RNaseL_inhibitor |
cd03222 |
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a ... |
140-214 |
3.94e-03 |
|
ATP-binding cassette domain of RNase L inhibitor; The ABC ATPase RNase L inhibitor (RLI) is a key enzyme in ribosomal biogenesis, formation of translation preinitiation complexes, and assembly of HIV capsids. RLI's are not transport proteins, and thus cluster with a group of soluble proteins that lack the transmembrane components commonly found in other members of the family. Structurally, RLI's have an N-terminal Fe-S domain and two nucleotide-binding domains, which are arranged to form two composite active sites in their interface cleft. RLI is one of the most conserved enzymes between archaea and eukaryotes with a sequence identity more than 48%. The high degree of evolutionary conservation suggests that RLI performs a central role in archaeal and eukaryotic physiology.
Pssm-ID: 213189 [Multi-domain] Cd Length: 177 Bit Score: 37.94 E-value: 3.94e-03
10 20 30 40 50 60 70
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 754651031 140 ELSGGQKQRVAIARALAPAPKVLLCDEATSALDPQTTRSILSLLKEINVKLGLTILLITHEMDVVKGICDDVAII 214
Cdd:cd03222 71 DLSGGELQRVAIAAALLRNATFYLFDEPSAYLDIEQRLNAARAIRRLSEEGKKTALVVEHDLAVLDYLSDRIHVF 145
|
|
| sufC |
PRK09580 |
cysteine desulfurase ATPase component; Reviewed |
21-172 |
7.10e-03 |
|
cysteine desulfurase ATPase component; Reviewed
Pssm-ID: 181965 [Multi-domain] Cd Length: 248 Bit Score: 37.46 E-value: 7.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 21 LRDVSLHVPQGKIFGVIGASGAGKSTLIRCVNLLE--RPTEGQVIVDGQDLVAL-PEREltlARRQIGMIFQhfnllssr 97
Cdd:PRK09580 17 LRGLNLEVRPGEVHAIMGPNGSGKSTLSATLAGREdyEVTGGTVEFKGKDLLELsPEDR---AGEGIFMAFQ-------- 85
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 754651031 98 tvfaniaFPLELAGWS-KSQIRARVDELLALVGLEA--------------RAHAYPSEL---------SGGQKQRVAIAR 153
Cdd:PRK09580 86 -------YPVEIPGVSnQFFLQTALNAVRSYRGQEPldrfdfqdlmeekiALLKMPEDLltrsvnvgfSGGEKKRNDILQ 158
|
170
....*....|....*....
gi 754651031 154 ALAPAPKVLLCDEATSALD 172
Cdd:PRK09580 159 MAVLEPELCILDESDSGLD 177
|
|
| |
