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Conserved domains on  [gi|753927005|ref|WP_041645920|]
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3-hydroxyacyl-CoA dehydrogenase NAD-binding domain-containing protein [Aromatoleum aromaticum]

Protein Classification

fatty acid beta-oxidation multifunctional protein( domain architecture ID 1002730)

fatty acid beta-oxidation multifunctional protein, similar to human peroxisomal bifunctional enzyme that possesses 2-enoyl-CoA hydratase, 3-hydroxyacyl-CoA dehydrogenase, and delta 3, delta 2-enoyl-CoA isomerase activities

Gene Ontology:  GO:0019395|GO:0006635
PubMed:  2303409

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
fadJ super family cl35999
fatty acid oxidation complex subunit alpha FadJ;
24-662 9.51e-159

fatty acid oxidation complex subunit alpha FadJ;


The actual alignment was detected with superfamily member PRK11154:

Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 474.00  E-value: 9.51e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDCRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:PRK11154  16 IAVITIDVPGEKMNTLKAEFAEQVRAILKQLREDKElKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK11154  96 EIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLR 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 183 ARRAKQLGLADECVPPRVMENAARMLVL-SRQRRRKPPLALRLMNG-PL-KSVVADRARKQVASKApREHYPAPYAIVDI 259
Cdd:PRK11154 176 AKQALKLGLVDDVVPHSILLEVAVELAKkGKPARRPLPVRERLLEGnPLgRALLFKQARKKTLAKT-QGNYPAPERILDV 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 260 WQRfggnalAVPAGHPASLEAILR-------SPTAKNLIRVFFLQERLKgfgksDDNSGDLAPRRVH---VVGAGVMGGD 329
Cdd:PRK11154 255 VRT------GLEKGMSSGYEAEARafgelamTPESAALRSIFFATTEMK-----KDTGSDAKPRPVNkvgVLGGGLMGGG 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 330 IAAVCA-LAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKA-RQVRFALdrLIPDPHGHGARRADVVIEAIFENL 407
Cdd:PRK11154 324 IAYVTAtKAGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSeRDKQMAL--ISGTTDYRGFKHADVVIEAVFEDL 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 408 DAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRL 487
Cdd:PRK11154 402 ALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALAKKQ 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 488 DKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAVDAALVAFGMPMGPVELVDTVGLDIALAAG---RALGGGAVA 564
Cdd:PRK11154 482 GKTPIVVRDGAGFYVNRILAPYINEAARLLLEGEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIpilEAALGERFS 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 565 VPKRLAELVAAGHLGRKSGQGYYRW-SDGKAQKTPVDT--------VPAG------LAARIVAPLLAATRRCVDEGVVAD 629
Cdd:PRK11154 562 APAAFDKLLNDDRKGRKNGRGFYLYgQKGKKSKKQVDEsvypllgiTPQSrlsaneIAERCVMLMLNEAVRCLDEGIIRS 641
                        650       660       670
                 ....*....|....*....|....*....|...
gi 753927005 630 ADLADAGVIFGTGFAPFTGGPLHYLASVGEKPL 662
Cdd:PRK11154 642 ARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEV 674
 
Name Accession Description Interval E-value
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
24-662 9.51e-159

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 474.00  E-value: 9.51e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDCRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:PRK11154  16 IAVITIDVPGEKMNTLKAEFAEQVRAILKQLREDKElKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK11154  96 EIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLR 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 183 ARRAKQLGLADECVPPRVMENAARMLVL-SRQRRRKPPLALRLMNG-PL-KSVVADRARKQVASKApREHYPAPYAIVDI 259
Cdd:PRK11154 176 AKQALKLGLVDDVVPHSILLEVAVELAKkGKPARRPLPVRERLLEGnPLgRALLFKQARKKTLAKT-QGNYPAPERILDV 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 260 WQRfggnalAVPAGHPASLEAILR-------SPTAKNLIRVFFLQERLKgfgksDDNSGDLAPRRVH---VVGAGVMGGD 329
Cdd:PRK11154 255 VRT------GLEKGMSSGYEAEARafgelamTPESAALRSIFFATTEMK-----KDTGSDAKPRPVNkvgVLGGGLMGGG 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 330 IAAVCA-LAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKA-RQVRFALdrLIPDPHGHGARRADVVIEAIFENL 407
Cdd:PRK11154 324 IAYVTAtKAGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSeRDKQMAL--ISGTTDYRGFKHADVVIEAVFEDL 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 408 DAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRL 487
Cdd:PRK11154 402 ALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALAKKQ 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 488 DKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAVDAALVAFGMPMGPVELVDTVGLDIALAAG---RALGGGAVA 564
Cdd:PRK11154 482 GKTPIVVRDGAGFYVNRILAPYINEAARLLLEGEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIpilEAALGERFS 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 565 VPKRLAELVAAGHLGRKSGQGYYRW-SDGKAQKTPVDT--------VPAG------LAARIVAPLLAATRRCVDEGVVAD 629
Cdd:PRK11154 562 APAAFDKLLNDDRKGRKNGRGFYLYgQKGKKSKKQVDEsvypllgiTPQSrlsaneIAERCVMLMLNEAVRCLDEGIIRS 641
                        650       660       670
                 ....*....|....*....|....*....|...
gi 753927005 630 ADLADAGVIFGTGFAPFTGGPLHYLASVGEKPL 662
Cdd:PRK11154 642 ARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEV 674
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
24-662 2.92e-120

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 375.71  E-value: 2.92e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005   24 VAWLHLDCRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:TIGR02441  23 VAVVKIDSPNSKVNTLSKELFAEFKEVMNELWTNEAiKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFE 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIR 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  183 ARRAKQLGLADECVPP-----------------RVMENAARMLVLSRQR-RRKPPLALRL----MNGPL-KSVVADRARK 239
Cdd:TIGR02441 183 ADRAKKMGIVDQLVDPlgpglkpaeentieyleEVAVKFAQGLANGKLSiNRDKGLVHKItqyvMTNPFvRQQVYKTAED 262
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  240 QVAsKAPREHYPAPYAIVDIWQRfggnalAVPAGHPASLEA-------ILRSPTAKNLIRVFFLQERLKG--FGKsddns 310
Cdd:TIGR02441 263 KVM-KQTKGLYPAPLKILDVVRT------GYDQGPDAGYEAeskafgeLSMTFESKALIGLFHGQTDCKKnkFGK----- 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  311 GDLAPRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKARQVRFaLDRLIPDPHG 390
Cdd:TIGR02441 331 PQRPVKTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKGLNKKVKRKKITSLERDSI-LSNLTPTLDY 409
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  391 HGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGE 470
Cdd:TIGR02441 410 SGFKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHD 489
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  471 ASDADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAVDAALVAFGMPMGPVELVDTVGLDI 550
Cdd:TIGR02441 490 GTSKDTLASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQEGVDPKKLDKLTTKFGFPVGAATLADEVGVDV 569
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  551 ALAAGRALGGGAVA-----VPKRLAELVAAGHLGRKSGQGYYRWSDGKAQKTPVD------------------TVPAGLA 607
Cdd:TIGR02441 570 AEHVAEDLGKAFGErfgggSAELLSELVKAGFLGRKSGKGIFIYQEGKKGSKKVNsdadeilaqyklppkaevSSPEDIQ 649
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 753927005  608 ARIVAPLLAATRRCVDEGVVADADLADAGVIFGTGFAPFTGGPLHYLASVGEKPL 662
Cdd:TIGR02441 650 IRLVSRFVNEAVLCLEEGILASPSEGDIGAVFGLGFPPFLGGPFRFVDLYGADKL 704
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
314-589 1.17e-107

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 327.45  E-value: 1.17e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 314 APRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKArQVRFALDRLIPDPHGHGA 393
Cdd:COG1250    1 EIKKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDLAAL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 394 RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:COG1250   80 ADADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATS 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 474 ADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALV-AFGMPMGPVELVDTVGLD-- 549
Cdd:COG1250  160 DETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYLNEAIRLLEEGVAsPEDIDAAMRlGFGFPMGPFELADLVGLDta 239
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 753927005 550 --IALAAGRALGGGAVAVPKRLAELVAAGHLGRKSGQGYYRW 589
Cdd:COG1250  240 laVLEVLYEALGDPRYRPPPLLKKLVEAGRLGRKTGRGFYDY 281
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
317-495 1.91e-53

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 181.58  E-value: 1.91e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  317 RVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFER---KLRGDTATKARqvrfALDRLIPDPHGHGA 393
Cdd:pfam02737   1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERlveKGRITEEEVDA----ALARISFTTDLAAA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  394 RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:pfam02737  77 VDADLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTS 156
                         170       180
                  ....*....|....*....|..
gi 753927005  474 ADALYRAAAFVRRLDKLPLPVR 495
Cdd:pfam02737 157 PETVATTVELAKKIGKTPVVVK 178
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
24-206 3.37e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 162.34  E-value: 3.37e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRL-DSPQAARDLVGRGWELF 101
Cdd:cd06558    9 VATITLN-RPEKRNALSLEMLDELAAALDEAEADPDvRVVVLTGAGKA-FCAGADLKELAALsDAGEEARAFIRELQELL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 102 NRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSV 181
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAED--AKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180
                 ....*....|....*....|....*
gi 753927005 182 DARRAKQLGLADECVPPRVMENAAR 206
Cdd:cd06558  165 SAEEALELGLVDEVVPDEELLAAAL 189
 
Name Accession Description Interval E-value
fadJ PRK11154
fatty acid oxidation complex subunit alpha FadJ;
24-662 9.51e-159

fatty acid oxidation complex subunit alpha FadJ;


Pssm-ID: 236864 [Multi-domain]  Cd Length: 708  Bit Score: 474.00  E-value: 9.51e-159
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDCRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:PRK11154  16 IAVITIDVPGEKMNTLKAEFAEQVRAILKQLREDKElKGVVFISGKPDNFIAGADINMLAACKTAQEAEALARQGQQLFA 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK11154  96 EIEALPIPVVAAIHGACLGGGLELALACHYRVCTDDPKTVLGLPEVQLGLLPGSGGTQRLPRLIGVSTALDMILTGKQLR 175
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 183 ARRAKQLGLADECVPPRVMENAARMLVL-SRQRRRKPPLALRLMNG-PL-KSVVADRARKQVASKApREHYPAPYAIVDI 259
Cdd:PRK11154 176 AKQALKLGLVDDVVPHSILLEVAVELAKkGKPARRPLPVRERLLEGnPLgRALLFKQARKKTLAKT-QGNYPAPERILDV 254
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 260 WQRfggnalAVPAGHPASLEAILR-------SPTAKNLIRVFFLQERLKgfgksDDNSGDLAPRRVH---VVGAGVMGGD 329
Cdd:PRK11154 255 VRT------GLEKGMSSGYEAEARafgelamTPESAALRSIFFATTEMK-----KDTGSDAKPRPVNkvgVLGGGLMGGG 323
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 330 IAAVCA-LAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKA-RQVRFALdrLIPDPHGHGARRADVVIEAIFENL 407
Cdd:PRK11154 324 IAYVTAtKAGLPVRIKDINPQGINHALKYSWDLLDKKVKRRHLKPSeRDKQMAL--ISGTTDYRGFKHADVVIEAVFEDL 401
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 408 DAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRL 487
Cdd:PRK11154 402 ALKQQMVAEVEQNCAPHTIFASNTSSLPIGQIAAAAARPEQVIGLHYFSPVEKMPLVEVIPHAKTSAETIATTVALAKKQ 481
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 488 DKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAVDAALVAFGMPMGPVELVDTVGLDIALAAG---RALGGGAVA 564
Cdd:PRK11154 482 GKTPIVVRDGAGFYVNRILAPYINEAARLLLEGEPIEHIDAALVKFGFPVGPITLLDEVGIDVGTKIIpilEAALGERFS 561
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 565 VPKRLAELVAAGHLGRKSGQGYYRW-SDGKAQKTPVDT--------VPAG------LAARIVAPLLAATRRCVDEGVVAD 629
Cdd:PRK11154 562 APAAFDKLLNDDRKGRKNGRGFYLYgQKGKKSKKQVDEsvypllgiTPQSrlsaneIAERCVMLMLNEAVRCLDEGIIRS 641
                        650       660       670
                 ....*....|....*....|....*....|...
gi 753927005 630 ADLADAGVIFGTGFAPFTGGPLHYLASVGEKPL 662
Cdd:PRK11154 642 ARDGDIGAVFGIGFPPFLGGPFRYMDSLGAGEV 674
fadB PRK11730
fatty acid oxidation complex subunit alpha FadB;
37-658 3.33e-135

fatty acid oxidation complex subunit alpha FadB;


Pssm-ID: 183293 [Multi-domain]  Cd Length: 715  Bit Score: 413.49  E-value: 3.33e-135
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRL-DSPQAA-RDLVGRGWELFNRLVRLRFPTLA 113
Cdd:PRK11730  29 NKLDRATLASLGEALDALEAQSDlKGLLLTSAKDA-FIVGADITEFLSLfAAPEEElSQWLHFANSIFNRLEDLPVPTVA 107
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 114 LIRGHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLAD 193
Cdd:PRK11730 108 AINGYALGGGCECVLATDYRVA--SPDARIGLPETKLGIMPGFGGTVRLPRLIGADNALEWIAAGKDVRAEDALKVGAVD 185
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 194 ECVPPRVMENAARMLV-------LSRQRRRKPPLA-LRLmnGPLKSVVA-DRARKQVASKAPReHYPAPYAIVDIWQRFG 264
Cdd:PRK11730 186 AVVAPEKLQEAALALLkqaiagkLDWKARRQPKLEpLKL--SKIEAMMSfTTAKGMVAQKAGK-HYPAPMTAVKTIEAAA 262
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 265 G----NALAVPAGHPASLEailRSPTAKNLIRVFFLQERLKG-FGKSDDNSGDlaPRRVHVVGAGVMGGDIAAVCALAGM 339
Cdd:PRK11730 263 GlgrdEALELEAKGFVKLA---KTNVARALVGIFLNDQYVKGkAKKLAKDAKP--VKQAAVLGAGIMGGGIAYQSASKGV 337
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 340 TVTLQDQAVERIAPAVGRAAKLFERKL-RGD-TATKARQVrfaLDRLIPDPHGHGARRADVVIEAIFENLDAKRALFAQL 417
Cdd:PRK11730 338 PVIMKDINQKALDLGMTEAAKLLNKQVeRGKiDGAKMAGV---LSSIRPTLDYAGFERVDVVVEAVVENPKVKAAVLAEV 414
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 418 ERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRLDKLPLPVRSA 497
Cdd:PRK11730 415 EQKVREDTILASNTSTISISLLAKALKRPENFCGMHFFNPVHRMPLVEVIRGEKTSDETIATVVAYASKMGKTPIVVNDC 494
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 498 PGFLVNAVLGPYMLEALRCVEEGVAPEAVDAAL-VAFGMPMGPVELVDTVGLDIalaAGRALGGGAVAVPKRLAE----- 571
Cdd:PRK11730 495 PGFFVNRVLFPYFAGFSQLLRDGADFRQIDKVMeKQFGWPMGPAYLLDVVGIDT---AHHAQAVMAEGFPDRMKKdyrda 571
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 572 ---LVAAGHLGRKSGQGYYRWS---DGKAQKTPVDTVPAGLA---------------ARIVAPLLAATRRCVDEGVVADA 630
Cdd:PRK11730 572 idvLFEAKRFGQKNGKGFYRYEedkKGKPKKEVDPAVYELLApvvqpkrefsdeeiiARMMIPMINEVVRCLEEGIVASP 651
                        650       660
                 ....*....|....*....|....*...
gi 753927005 631 DLADAGVIFGTGFAPFTGGPLHYLASVG 658
Cdd:PRK11730 652 AEADMALVYGLGFPPFRGGAFRYLDTLG 679
fa_ox_alpha_mit TIGR02441
fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of ...
24-662 2.92e-120

fatty acid oxidation complex, alpha subunit, mitochondrial; Members represent alpha subunit of mitochondrial multifunctional fatty acid degradation enzyme complex. Subunit activities include: enoyl-CoA hydratase (EC 4.2.1.17) _ 3-hydroxyacyl-CoA dehydrogenase (EC 1.1.1.35). Some characterization in human (SP:P40939), pig (SP:Q29554), and rat (SP:Q64428). The beta subunit has activity: acetyl-CoA C-acyltransferase (EC 2.3.1.16).


Pssm-ID: 131494 [Multi-domain]  Cd Length: 737  Bit Score: 375.71  E-value: 2.92e-120
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005   24 VAWLHLDCRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:TIGR02441  23 VAVVKIDSPNSKVNTLSKELFAEFKEVMNELWTNEAiKSAVLISGKPGSFVAGADIQMIAACKTAQEVTQLSQEGQEMFE 102
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:TIGR02441 103 RIEKSQKPIVAAISGSCLGGGLELALACHYRIATKDRKTLLGLPEVMLGLLPGAGGTQRLPKLTGVPAALDMMLTGKKIR 182
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  183 ARRAKQLGLADECVPP-----------------RVMENAARMLVLSRQR-RRKPPLALRL----MNGPL-KSVVADRARK 239
Cdd:TIGR02441 183 ADRAKKMGIVDQLVDPlgpglkpaeentieyleEVAVKFAQGLANGKLSiNRDKGLVHKItqyvMTNPFvRQQVYKTAED 262
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  240 QVAsKAPREHYPAPYAIVDIWQRfggnalAVPAGHPASLEA-------ILRSPTAKNLIRVFFLQERLKG--FGKsddns 310
Cdd:TIGR02441 263 KVM-KQTKGLYPAPLKILDVVRT------GYDQGPDAGYEAeskafgeLSMTFESKALIGLFHGQTDCKKnkFGK----- 330
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  311 GDLAPRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKARQVRFaLDRLIPDPHG 390
Cdd:TIGR02441 331 PQRPVKTLAVLGAGLMGAGIAQVSVDKGLKTVLKDATPAGLDRGQQQVFKGLNKKVKRKKITSLERDSI-LSNLTPTLDY 409
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  391 HGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGE 470
Cdd:TIGR02441 410 SGFKNADMVIEAVFEDLSLKHKVIKEVEAVVPPHCIIASNTSALPIKDIAAVSSRPEKVIGMHYFSPVDKMQLLEIITHD 489
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  471 ASDADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEAVDAALVAFGMPMGPVELVDTVGLDI 550
Cdd:TIGR02441 490 GTSKDTLASAVAVGLKQGKVVIVVKDGPGFYTTRCLGPMLAEVIRLLQEGVDPKKLDKLTTKFGFPVGAATLADEVGVDV 569
                         570       580       590       600       610       620       630       640
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  551 ALAAGRALGGGAVA-----VPKRLAELVAAGHLGRKSGQGYYRWSDGKAQKTPVD------------------TVPAGLA 607
Cdd:TIGR02441 570 AEHVAEDLGKAFGErfgggSAELLSELVKAGFLGRKSGKGIFIYQEGKKGSKKVNsdadeilaqyklppkaevSSPEDIQ 649
                         650       660       670       680       690
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 753927005  608 ARIVAPLLAATRRCVDEGVVADADLADAGVIFGTGFAPFTGGPLHYLASVGEKPL 662
Cdd:TIGR02441 650 IRLVSRFVNEAVLCLEEGILASPSEGDIGAVFGLGFPPFLGGPFRFVDLYGADKL 704
FadB COG1250
3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA ...
314-589 1.17e-107

3-hydroxyacyl-CoA dehydrogenase [Lipid transport and metabolism]; 3-hydroxyacyl-CoA dehydrogenase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440862 [Multi-domain]  Cd Length: 281  Bit Score: 327.45  E-value: 1.17e-107
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 314 APRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKArQVRFALDRLIPDPHGHGA 393
Cdd:COG1250    1 EIKKVAVIGAGTMGAGIAAVFANAGYEVVLLDISPEALERARARIAKLLDKLVKKGKLTEE-EADAALARITPTTDLAAL 79
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 394 RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:COG1250   80 ADADLVIEAVPEDLDLKQEVFAELDAVAPPDAILASNTSSLSITELAAATKRPERFIGLHFFNPVPLMPLVEVIRGPATS 159
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 474 ADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALV-AFGMPMGPVELVDTVGLD-- 549
Cdd:COG1250  160 DETVATAVAFARRLGKTPVVVKDTPGFIVNRILVPYLNEAIRLLEEGVAsPEDIDAAMRlGFGFPMGPFELADLVGLDta 239
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 753927005 550 --IALAAGRALGGGAVAVPKRLAELVAAGHLGRKSGQGYYRW 589
Cdd:COG1250  240 laVLEVLYEALGDPRYRPPPLLKKLVEAGRLGRKTGRGFYDY 281
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
316-677 4.71e-71

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 239.36  E-value: 4.71e-71
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKL-RGDTATKARQVrfALDRLIPDPHGHGAR 394
Cdd:PRK08268   8 ATVAVIGAGAMGAGIAQVAAQAGHTVLLYDARAGAAAAARDGIAARLAKLVeKGKLTAEQADA--ALARLRPVEALADLA 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 395 RADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDA 474
Cdd:PRK08268  86 DCDLVVEAIVERLDVKQALFAQLEAIVSPDCILATNTSSLSITAIAAALKHPERVAGLHFFNPVPLMKLVEVVSGLATDP 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 475 DALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAAL-VAFGMPMGPVELVDTVGLDIAL 552
Cdd:PRK08268 166 AVADALYALARAWGKTPVRAKDTPGFIVNRAARPYYTEALRVLEEGVAdPATIDAILrEAAGFRMGPFELMDLIGLDVNH 245
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 553 AAGRALGGGAVAVPK-----RLAELVAAGHLGRKSGQGYYRWSDGKAQKTPVDTVPAGLAARIVAPLLAAtrrcvDEGVV 627
Cdd:PRK08268 246 AVMESVYRQFYQEPRfrpslIQQELVAAGRLGRKSGQGFYRYADGAKQPPAEAAPPAALPPVWVSADVEG-----DLAAL 320
                        330       340       350       360       370
                 ....*....|....*....|....*....|....*....|....*....|
gi 753927005 628 ADAdLADAGVIFGTGFAPFTGGplhyLASVGEKPLDAASARRDDAIVSAR 677
Cdd:PRK08268 321 ARL-LERLGATIETGEGPSADG----LVLLAPTGGDTTTAAAREGLDAAR 365
PLN02545 PLN02545
3-hydroxybutyryl-CoA dehydrogenase
316-599 1.02e-59

3-hydroxybutyryl-CoA dehydrogenase


Pssm-ID: 215300 [Multi-domain]  Cd Length: 295  Bit Score: 202.65  E-value: 1.02e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQD-------QAVERIAPAVGRAAKlfERKLRGDTATKA-RQVRFALDRlipd 387
Cdd:PLN02545   5 KKVGVVGAGQMGSGIAQLAAAAGMDVWLLDsdpaalsRGLDSISSSLARLVK--KGKMSQEEADATlGRIRCTTNL---- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 388 phgHGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVV 467
Cdd:PLN02545  79 ---EELRDADFIIEAIVESEDLKKKLFSELDRICKPSAILASNTSSISITRLASATQRPQQVIGMHFMNPPPIMKLVEII 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 468 AGEASDADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAAL-VAFGMPMGPVELVDT 545
Cdd:PLN02545 156 RGADTSDEVFDATKALAERFGKTVVCSQDYPGFIVNRILMPMINEAFYALYTGVAsKEDIDTGMkLGTNHPMGPLHLADF 235
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 753927005 546 VGLD----IALAAGRALGGGAVAVPKRLAELVAAGHLGRKSGQGYYRWsDGKAQKTPV 599
Cdd:PLN02545 236 IGLDtclsIMKVLHEGLGDSKYRPCPLLVQYVDAGRLGRKSGRGVYHY-DGKKRGDPP 292
PRK05808 PRK05808
3-hydroxybutyryl-CoA dehydrogenase; Validated
316-587 1.08e-59

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 180269 [Multi-domain]  Cd Length: 282  Bit Score: 202.12  E-value: 1.08e-59
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKARQVRfALDRLIPDPHGHGARR 395
Cdd:PRK05808   4 QKIGVIGAGTMGNGIAQVCAVAGYDVVMVDISDAAVDRGLATITKSLDRLVKKGKMTEADKEA-ALARITGTTDLDDLKD 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 396 ADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDAD 475
Cdd:PRK05808  83 ADLVIEAATENMDLKKKIFAQLDEIAKPEAILATNTSSLSITELAAATKRPDKVIGMHFFNPVPVMKLVEIIRGLATSDA 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 476 ALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALvAFGM--PMGPVELVDTVGLDIAL 552
Cdd:PRK05808 163 THEAVEALAKKIGKTPVEVKNAPGFVVNRILIPMINEAIFVLAEGVAtAEDIDEGM-KLGCnhPIGPLALADLIGLDTCL 241
                        250       260       270
                 ....*....|....*....|....*....|....*....
gi 753927005 553 AAGRALGGGAVAVPKR----LAELVAAGHLGRKSGQGYY 587
Cdd:PRK05808 242 AIMEVLYEGFGDSKYRpcplLRKMVAAGWLGRKTGRGFY 280
PRK07819 PRK07819
3-hydroxybutyryl-CoA dehydrogenase; Validated
316-587 8.43e-57

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181133 [Multi-domain]  Cd Length: 286  Bit Score: 194.43  E-value: 8.43e-57
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKL-RGDTATKARQVRFALDRLIPDPHGHGAR 394
Cdd:PRK07819   6 QRVGVVGAGQMGAGIAEVCARAGVDVLVFETTEELATAGRNRIEKSLERAVsRGKLTERERDAALARLRFTTDLGDFADR 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 395 raDVVIEAIFENLDAKRALFAQLER-RARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:PRK07819  86 --QLVIEAVVEDEAVKTEIFAELDKvVTDPDAVLASNTSSIPIMKLAAATKRPGRVLGLHFFNPVPVLPLVELVPTLVTS 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 474 ADALYRAAAFVRR-LDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALVA-FGMPMGPVELVDTVGLDI 550
Cdd:PRK07819 164 EATVARAEEFASDvLGKQVVRAQDRSGFVVNALLVPYLLSAIRMVESGFAtAEDIDKAMVLgCAHPMGPLRLSDLVGLDT 243
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 753927005 551 ALAAGRAL----GGGAVAVPKRLAELVAAGHLGRKSGQGYY 587
Cdd:PRK07819 244 VKAIADSMyeefKEPLYAPPPLLLRMVEAGLLGKKSGRGFY 284
PRK07530 PRK07530
3-hydroxybutyryl-CoA dehydrogenase; Validated
316-601 7.28e-55

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181018 [Multi-domain]  Cd Length: 292  Bit Score: 189.45  E-value: 7.28e-55
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKL-RGDTATKARQVrfALDRLIPDPHGHGAR 394
Cdd:PRK07530   5 KKVGVIGAGQMGNGIAHVCALAGYDVLLNDVSADRLEAGLATINGNLARQVaKGKISEEARAA--ALARISTATDLEDLA 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 395 RADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDa 474
Cdd:PRK07530  83 DCDLVIEAATEDETVKRKIFAQLCPVLKPEAILATNTSSISITRLASATDRPERFIGIHFMNPVPVMKLVELIRGIATD- 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 475 DALYRAA-AFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAP-EAVDAAL-VAFGMPMGPVELVDTVGLDIA 551
Cdd:PRK07530 162 EATFEAAkEFVTKLGKTITVAEDFPAFIVNRILLPMINEAIYTLYEGVGSvEAIDTAMkLGANHPMGPLELADFIGLDTC 241
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 753927005 552 LAAGRALGGGAVAVPKR----LAELVAAGHLGRKSGQGYYRWSdgkaQKTPVDT 601
Cdd:PRK07530 242 LSIMQVLHDGLADSKYRpcplLVKYVEAGWLGRKTGRGFYDYR----GEVPVPT 291
3HCDH_N pfam02737
3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda ...
317-495 1.91e-53

3-hydroxyacyl-CoA dehydrogenase, NAD binding domain; This family also includes lambda crystallin.


Pssm-ID: 397037 [Multi-domain]  Cd Length: 180  Bit Score: 181.58  E-value: 1.91e-53
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  317 RVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFER---KLRGDTATKARqvrfALDRLIPDPHGHGA 393
Cdd:pfam02737   1 KVAVIGAGTMGAGIAQVFALAGLEVVLVDISEEALEKALERIESSLERlveKGRITEEEVDA----ALARISFTTDLAAA 76
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  394 RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:pfam02737  77 VDADLVIEAVPENLELKRKLFAELDAIAPPDAILATNTSSLSITELAAATKRPERFIGLHFFNPPPLMPLVEVVRGEKTS 156
                         170       180
                  ....*....|....*....|..
gi 753927005  474 ADALYRAAAFVRRLDKLPLPVR 495
Cdd:pfam02737 157 PETVATTVELAKKIGKTPVVVK 178
PRK09260 PRK09260
3-hydroxyacyl-CoA dehydrogenase;
317-592 4.20e-51

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 236434 [Multi-domain]  Cd Length: 288  Bit Score: 179.22  E-value: 4.20e-51
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 317 RVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKArQVRFALDRLIPDPH-GHGARR 395
Cdd:PRK09260   3 KLVVVGAGVMGRGIAYVFAVSGFQTTLVDIKQEQLESAQQEIASIFEQGVARGKLTEA-ARQAALARLSYSLDlKAAVAD 81
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 396 ADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDAD 475
Cdd:PRK09260  82 ADLVIEAVPEKLELKKAVFETADAHAPAECYIATNTSTMSPTEIASFTKRPERVIAMHFFNPVHKMKLVELIRGLETSDE 161
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 476 ALYRAAAFVRRLDKLPLPVRSAPGFL---VNAVLGPymlEALRCVEEGVA-PEAVDAAL-VAFGMPMGPVELVDTVGLD- 549
Cdd:PRK09260 162 TVQVAKEVAEQMGKETVVVNEFPGFVtsrISALVGN---EAFYMLQEGVAtAEDIDKAIrLGLNFPMGPLELGDLVGLDt 238
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 753927005 550 -IALAAGRALGGGAVAVPKRLAE-LVAAGHLGRKSGQGYYRWSDG 592
Cdd:PRK09260 239 rLNNLKYLHETLGEKYRPAPLLEkYVKAGRLGRKTGRGVYDYTNR 283
CaiD COG1024
Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase ...
24-225 2.75e-47

Enoyl-CoA hydratase/carnithine racemase [Lipid transport and metabolism]; Enoyl-CoA hydratase/carnithine racemase is part of the Pathway/BioSystem: Fatty acid biosynthesis


Pssm-ID: 440647 [Multi-domain]  Cd Length: 249  Bit Score: 167.27  E-value: 2.75e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:COG1024    9 VATITLN-RPEKLNALSLEMLAELAAALDEAEADPDvRVVVLTGAGKA-FCAGADLKELAAAADPEEARAFARGLQRLFR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:COG1024   87 ALRRLPKPVIAAVNGAALGGGLELALACDLRIAAED--ARFGLPEVRLGLIPGGGGTQRLPRLVGLARAKELLLTGRRID 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 753927005 183 ARRAKQLGLADECVPPRVMENAARMLVlsRQRRRKPPLALRLM 225
Cdd:COG1024  165 AEEALELGLVNRVVPDDELLAAALALA--ARLAAGPPLALAAT 205
crotonase-like cd06558
Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse ...
24-206 3.37e-46

Crotonase/Enoyl-Coenzyme A (CoA) hydratase superfamily. This superfamily contains a diverse set of enzymes including enoyl-CoA hydratase, napthoate synthase, methylmalonyl-CoA decarboxylase, 3-hydoxybutyryl-CoA dehydratase, and dienoyl-CoA isomerase. Many of these play important roles in fatty acid metabolism. In addition to a conserved structural core and the formation of trimers (or dimers of trimers), a common feature in this superfamily is the stabilization of an enolate anion intermediate derived from an acyl-CoA substrate. This is accomplished by two conserved backbone NH groups in active sites that form an oxyanion hole.


Pssm-ID: 119339 [Multi-domain]  Cd Length: 195  Bit Score: 162.34  E-value: 3.37e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRL-DSPQAARDLVGRGWELF 101
Cdd:cd06558    9 VATITLN-RPEKRNALSLEMLDELAAALDEAEADPDvRVVVLTGAGKA-FCAGADLKELAALsDAGEEARAFIRELQELL 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 102 NRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSV 181
Cdd:cd06558   87 RALLRLPKPVIAAVNGAALGGGLELALACDIRIAAED--AKFGLPEVKLGLVPGGGGTQRLPRLVGPARARELLLTGRRI 164
                        170       180
                 ....*....|....*....|....*
gi 753927005 182 DARRAKQLGLADECVPPRVMENAAR 206
Cdd:cd06558  165 SAEEALELGLVDEVVPDEELLAAAL 189
PRK06130 PRK06130
3-hydroxybutyryl-CoA dehydrogenase; Validated
316-590 2.46e-45

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 235707 [Multi-domain]  Cd Length: 311  Bit Score: 163.79  E-value: 2.46e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAveriAPAVGRAAKLFERKL----RGDTATKARQ-VRFALDRlipdphG 390
Cdd:PRK06130   5 QNLAIIGAGTMGSGIAALFARKGLQVVLIDVM----EGALERARGVIERALgvyaPLGIASAGMGrIRMEAGL------A 74
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 391 HGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGE 470
Cdd:PRK06130  75 AAVSGADLVIEAVPEKLELKRDVFARLDGLCDPDTIFATNTSGLPITAIAQAVTRPERFVGTHFFTPADVIPLVEVVRGD 154
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 471 ASDADALYRAAAFVRRLDKLPLPV-RSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDaALVAFGMPM-----GPVELV 543
Cdd:PRK06130 155 KTSPQTVATTMALLRSIGKRPVLVkKDIPGFIANRIQHALAREAISLLEKGVAsAEDID-EVVKWSLGIrlaltGPLEQR 233
                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 753927005 544 DTVGLDIALAAGR---ALGGGAVAVPKRLAELVAAGHLGRKSGQGYYRWS 590
Cdd:PRK06130 234 DMNGLDVHLAVASylyQDLENRTTPSPLLEEKVEAGELGAKSGQGFYAWP 283
PRK06035 PRK06035
3-hydroxyacyl-CoA dehydrogenase; Validated
316-581 2.04e-43

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 180361 [Multi-domain]  Cd Length: 291  Bit Score: 158.11  E-value: 2.04e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVG--RAAKLFERKLRGDTATKARQVRFALDRLIPDPHGHGA 393
Cdd:PRK06035   4 KVIGVVGSGVMGQGIAQVFARTGYDVTIVDVSEEILKNAMEliESGPYGLRNLVEKGKMSEDEAKAIMARIRTSTSYESL 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 394 RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASD 473
Cdd:PRK06035  84 SDADFIVEAVPEKLDLKRKVFAELERNVSPETIIASNTSGIMIAEIATALERKDRFIGMHWFNPAPVMKLIEVVRAALTS 163
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 474 ADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVAPEA-VDA-ALVAFGMPMGPVELVDTVGLD-- 549
Cdd:PRK06035 164 EETFNTTVELSKKIGKIPIEVADVPGFFTTRFIEGWLLEAIRSFEIGIATIKdIDEmCKLAFGFPMGPFELMDIIGIDtv 243
                        250       260       270
                 ....*....|....*....|....*....|....
gi 753927005 550 --IALAAGRALGGGAVAVPKRLAELVAAGHLGRK 581
Cdd:PRK06035 244 yhIAEYLYEETGDPQFIPPNSLKQMVLNGYVGDK 277
PRK08293 PRK08293
3-hydroxyacyl-CoA dehydrogenase;
316-589 6.43e-42

3-hydroxyacyl-CoA dehydrogenase;


Pssm-ID: 181359 [Multi-domain]  Cd Length: 287  Bit Score: 153.56  E-value: 6.43e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 316 RRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKARQVRFALDRL-IPDPHGHGAR 394
Cdd:PRK08293   4 KNVTVAGAGVLGSQIAFQTAFHGFDVTIYDISDEALEKAKERIAKLADRYVRDLEATKEAPAEAALNRItLTTDLAEAVK 83
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 395 RADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVaGEASDA 474
Cdd:PRK08293  84 DADLVIEAVPEDPEIKGDFYEELAKVAPEKTIFATNSSTLLPSQFAEATGRPEKFLALHFANEIWKNNTAEIM-GHPGTD 162
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 475 DALYRAA-AFVRRLDKLPLPV-RSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAA-LVAFGMPMGPVELVDTVGLD- 549
Cdd:PRK08293 163 PEVFDTVvAFAKAIGMVPIVLkKEQPGYILNSLLVPFLSAALALWAKGVAdPETIDKTwMIATGAPMGPFGILDIVGLDt 242
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....
gi 753927005 550 ----IALAAGRALGGGAVAVPKRLAELVAAGHLGRKSGQGYYRW 589
Cdd:PRK08293 243 ayniTSNWAEATDDENAKKAAALLKEYIDKGKLGVATGEGFYNY 286
PRK07658 PRK07658
enoyl-CoA hydratase; Provisional
37-224 1.23e-38

enoyl-CoA hydratase; Provisional


Pssm-ID: 181070 [Multi-domain]  Cd Length: 257  Bit Score: 143.62  E-value: 1.23e-38
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFNRLVRLRFPTLALIR 116
Cdd:PRK07658  23 NALSSQVLHELSELLDQVEKDDNVRVVVIHGEGRFFSAGADIKEFTSVTEAEQATELAQLGQVTFERVEKFSKPVIAAIH 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 117 GHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADECV 196
Cdd:PRK07658 103 GAALGGGLELAMSCHIRFA--TESAKLGLPELNLGLIPGFAGTQRLPRYVGKAKALEMMLTSEPITGAEALKWGLVNGVF 180
                        170       180
                 ....*....|....*....|....*....
gi 753927005 197 P-PRVMENAarmLVLSRQRRRKPPLALRL 224
Cdd:PRK07658 181 PeETLLDDA---KKLAKKIAGKSPATTRA 206
PRK07657 PRK07657
enoyl-CoA hydratase; Provisional
32-224 1.11e-30

enoyl-CoA hydratase; Provisional


Pssm-ID: 181069 [Multi-domain]  Cd Length: 260  Bit Score: 120.99  E-value: 1.11e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIAS-AKPAGFIAGADIEEFTRLDSPQAaRDLVGRGWELFNRLVRLRFP 110
Cdd:PRK07657  21 RPRAANALSLALLEELQNILTQINEEANVRVVILTgAGEKAFCAGADLKERAGMNEEQV-RHAVSLIRTTMEMVEQLPQP 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLG 190
Cdd:PRK07657 100 VIAAINGIALGGGLELALACDFRIAAES--ASLGLTETTLAIIPGAGGTQRLPRLIGVGRAKELIYTGRRISAQEAKEIG 177
                        170       180       190
                 ....*....|....*....|....*....|....
gi 753927005 191 LADECVPPRVMENAArmLVLSRQRRRKPPLALRL 224
Cdd:PRK07657 178 LVEFVVPAHLLEEKA--IEIAEKIASNGPIAVRQ 209
PLN02600 PLN02600
enoyl-CoA hydratase
24-224 7.63e-30

enoyl-CoA hydratase


Pssm-ID: 178210 [Multi-domain]  Cd Length: 251  Bit Score: 118.37  E-value: 7.63e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQ-PPKGLVIASAKPAGFIAGADIEEfTRLDSPQAARDLVGRGWELFN 102
Cdd:PLN02600   5 IVELRLD-RPEAKNAIGKEMLRGLRSAFEKIQADaSARVVMLRSSVPGVFCAGADLKE-RRKMSPSEVQKFVNSLRSTFS 82
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PLN02600  83 SLEALSIPTIAVVEGAALGGGLELALSCDLRICGEE--AVFGLPETGLAIIPGAGGTQRLPRLVGRSRAKELIFTGRRIG 160
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 753927005 183 ARRAKQLGLADECVPprVMENAARMLVLSRQRRRKPPLALRL 224
Cdd:PLN02600 161 AREAASMGLVNYCVP--AGEAYEKALELAQEINQKGPLAIKM 200
PRK08269 PRK08269
3-hydroxybutyryl-CoA dehydrogenase; Validated
326-591 7.74e-29

3-hydroxybutyryl-CoA dehydrogenase; Validated


Pssm-ID: 181340 [Multi-domain]  Cd Length: 314  Bit Score: 117.47  E-value: 7.74e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 326 MGGDIAAVCALAGMTVTLQDQaveRIAPAVGRAAklFERKLRGD-TATKARQVRF----------ALDRLIPDPHGHGA- 393
Cdd:PRK08269   1 MGQGIALAFAFAGHDVTLIDF---KPRDAAGWRA--LDAEARAEiERTLAALVALgridaaqadaVLARIAVVARDGAAd 75
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 394 --RRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEA 471
Cdd:PRK08269  76 alADADLVFEAVPEVLDAKREALRWLGRHVDADAIIASTTSTFLVTDLQRHVAHPERFLNAHWLNPAYLMPLVEVSPSDA 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 472 SDADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAAL-VAFGMP---MGPVELVDTV 546
Cdd:PRK08269 156 TDPAVVDRLAALLERIGKVPVVCGPSPGYIVPRIQALAMNEAARMVEEGVAsAEDIDKAIrTGFGLRfavLGLLEFIDWG 235
                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*....
gi 753927005 547 GLDIALAAGRALGGGAVAVPKRLAELV----AAGHLGRKSGQGYYRWSD 591
Cdd:PRK08269 236 GCDILYYASRYLAGEIGPDRFAPPAIVvrnmEEGRDGLRTGAGFYDYAG 284
PRK09674 PRK09674
enoyl-CoA hydratase-isomerase; Provisional
32-230 6.43e-28

enoyl-CoA hydratase-isomerase; Provisional


Pssm-ID: 182026 [Multi-domain]  Cd Length: 255  Bit Score: 112.94  E-value: 6.43e-28
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWElfnRLVRLRFPT 111
Cdd:PRK09674  19 RPEARNALNNALLTQLVNELEAAATDTSIGVCVITGNARFFAAGADLNEMAEKDLAATLNDPRPQLWQ---RLQAFNKPL 95
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 112 LALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGL 191
Cdd:PRK09674  96 IAAVNGYALGAGCELALLCD--IVIAGENARFGLPEITLGIMPGAGGTQRLIRSVGKSLASQMVLTGESITAQQAQQAGL 173
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 753927005 192 ADECVPPRVmeNAARMLVLSRQRRRKPPLALRLMNGPLK 230
Cdd:PRK09674 174 VSEVFPPEL--TLERALQLASKIARHSPLALRAAKQALR 210
ECH_1 pfam00378
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
32-223 7.90e-28

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase.


Pssm-ID: 395302 [Multi-domain]  Cd Length: 251  Bit Score: 112.84  E-value: 7.90e-28
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005   32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAArDLVGRGWELFNRLVRLRFPT 111
Cdd:pfam00378  13 RPEAVNALSAELITELIQALEKLRTDPSVRAVVLTGGDKAFCAGADLKEMYGEGPAHQA-LYRENVLDLWTLLYTCPKPV 91
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  112 LALIRGHCLGGGLELALACRYRVVVDEPatKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGL 191
Cdd:pfam00378  92 IAAVNGYAIGGGCELALACDIIIAADNA--SFGLNETKLGIIPGAGGTDRLPRIIGHSKAMEMLLLGRRISAQEALKWGL 169
                         170       180       190
                  ....*....|....*....|....*....|..
gi 753927005  192 ADECVPPRVMENAARMLVlsRQRRRKPPLALR 223
Cdd:pfam00378 170 VDKVVPEDQLLDEARELA--EKLAEKSPAALA 199
PRK06143 PRK06143
enoyl-CoA hydratase; Provisional
28-211 3.27e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 180423  Cd Length: 256  Bit Score: 108.20  E-value: 3.27e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  28 HLDCRDAAT-NTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDsPQAARDLVGRGWELFNRLV 105
Cdd:PRK06143  19 TLTIRNAGSlNILGTPVILALTQALRWLAADPDvRVLVLRGAGEKAFIGGADIKEMATLD-QASAEAFISRLRDLCDAVR 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 106 RLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIvPAWGGMKRLPETIGAPAALDLMLTGKSVDARR 185
Cdd:PRK06143  98 HFPVPVIARIPGWCLGGGLELAAACDLRIAAHD--AQFGMPEVRVGI-PSVIHAALLPRLIGWARTRWLLLTGETIDAAQ 174
                        170       180
                 ....*....|....*....|....*.
gi 753927005 186 AKQLGLADECVPPRVMENAARMLVLS 211
Cdd:PRK06143 175 ALAWGLVDRVVPLAELDAAVERLAAS 200
PRK05862 PRK05862
enoyl-CoA hydratase; Provisional
24-204 4.31e-26

enoyl-CoA hydratase; Provisional


Pssm-ID: 180295 [Multi-domain]  Cd Length: 257  Bit Score: 107.82  E-value: 4.31e-26
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWElfnR 103
Cdd:PRK05862  14 VGLITLN-RPKALNALNDALMDELGAALAAFDADEGIGAIVITGSEKAFAAGADIKEMADLSFMDVYKGDYITNWE---K 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRLRFPTLALIRGHCLGGGLELALACRYRVVVDepATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDA 183
Cdd:PRK05862  90 VARIRKPVIAAVAGYALGGGCELAMMCDIIIAAD--TAKFGQPEIKLGVLPGMGGSQRLTRAVGKAKAMDLCLTGRMMDA 167
                        170       180
                 ....*....|....*....|..
gi 753927005 184 RRAKQLGLADECVPP-RVMENA 204
Cdd:PRK05862 168 AEAERAGLVSRVVPAdKLLDEA 189
PRK06129 PRK06129
3-hydroxyacyl-CoA dehydrogenase; Validated
314-544 1.27e-25

3-hydroxyacyl-CoA dehydrogenase; Validated


Pssm-ID: 235706 [Multi-domain]  Cd Length: 308  Bit Score: 107.82  E-value: 1.27e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 314 APRRVHVVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFER-----KLRGDTATKARQvRFALDRLIPDp 388
Cdd:PRK06129   1 PMGSVAIIGAGLIGRAWAIVFARAGHEVRLWDADPAAAAAAPAYIAGRLEDlaafdLLDGEAPDAVLA-RIRVTDSLAD- 78
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 389 hghGARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVA 468
Cdd:PRK06129  79 ---AVADADYVQESAPENLELKRALFAELDALAPPHAILASSTSALLASAFTEHLAGRERCLVAHPINPPYLIPVVEVVP 155
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 469 GEASDADALYRAAAFVRRLDKLPLPV-RSAPGFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALVAfGMP-----MGPVE 541
Cdd:PRK06129 156 APWTAPATLARAEALYRAAGQSPVRLrREIDGFVLNRLQGALLREAFRLVADGVAsVDDIDAVIRD-GLGlrwsfMGPFE 234

                 ...
gi 753927005 542 LVD 544
Cdd:PRK06129 235 TID 237
PRK05809 PRK05809
short-chain-enoyl-CoA hydratase;
32-224 5.65e-25

short-chain-enoyl-CoA hydratase;


Pssm-ID: 180270 [Multi-domain]  Cd Length: 260  Bit Score: 104.83  E-value: 5.65e-25
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLdSPQAARDLVGRGWELFNRLVRLRFP 110
Cdd:PRK05809  21 RPKALNALNSETLKELDTVLDDIENDDNvYAVILTGAGEKAFVAGADISEMKDL-NEEEGRKFGLLGNKVFRKLENLDKP 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLG 190
Cdd:PRK05809 100 VIAAINGFALGGGCELSMACDIRIASEK--AKFGQPEVGLGITPGFGGTQRLARIVGPGKAKELIYTGDMINAEEALRIG 177
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 753927005 191 LADECVPP-RVMENAARMlvlSRQRRRKPPLALRL 224
Cdd:PRK05809 178 LVNKVVEPeKLMEEAKAL---ANKIAANAPIAVKL 209
PRK06688 PRK06688
enoyl-CoA hydratase; Provisional
24-225 6.24e-24

enoyl-CoA hydratase; Provisional


Pssm-ID: 235852 [Multi-domain]  Cd Length: 259  Bit Score: 101.48  E-value: 6.24e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFtrLDSPQAARDLVGRGWELFNR 103
Cdd:PRK06688  15 VLTITIN-RPDKKNALTAAMYQALADALEAAATDPAVRVVVLTGAGRAFSAGGDIKDF--PKAPPKPPDELAPVNRFLRA 91
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDA 183
Cdd:PRK06688  92 IAALPKPVVAAVNGPAVGVGVSLALACDLVYASES--AKFSLPFAKLGLCPDAGGSALLPRLIGRARAAEMLLLGEPLSA 169
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 753927005 184 RRAKQLGLADECVPPRVMENAARMLVlsRQRRRKPPLALRLM 225
Cdd:PRK06688 170 EEALRIGLVNRVVPAAELDAEADAQA--AKLAAGPASALRYT 209
3HCDH pfam00725
3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda ...
499-589 8.97e-23

3-hydroxyacyl-CoA dehydrogenase, C-terminal domain; This family also includes lambda crystallin. Some proteins include two copies of this domain.


Pssm-ID: 395588 [Multi-domain]  Cd Length: 97  Bit Score: 93.05  E-value: 8.97e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  499 GFLVNAVLGPYMLEALRCVEEGVA-PEAVDAALV-AFGMPMGPVELVDTVGLD----IALAAGRALGGGAVAVPKRLAEL 572
Cdd:pfam00725   1 GFVVNRLLAPYLNEAIRLVEEGVAtPEDIDAAMRlGLGLPMGPFELSDLVGLDvgyhILEVLAEEFGDRAYRPPPLLEKL 80
                          90
                  ....*....|....*..
gi 753927005  573 VAAGHLGRKSGQGYYRW 589
Cdd:pfam00725  81 VEAGRLGRKTGKGFYKY 97
PRK09076 PRK09076
enoyl-CoA hydratase; Provisional
37-197 8.39e-22

enoyl-CoA hydratase; Provisional


Pssm-ID: 236373 [Multi-domain]  Cd Length: 258  Bit Score: 95.37  E-value: 8.39e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSpQAARDLVGRGWELFNRLVRLRFPTLALI 115
Cdd:PRK09076  24 NTWTADSLQALKQLVLELNADKDvYALVITGDGEKFFSAGADLNLFADGDK-AVAREMARRFGEAFEALSAFRGVSIAAI 102
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 116 RGHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADEC 195
Cdd:PRK09076 103 NGYAMGGGLECALACDIRIA--EEQAQMALPEASVGLLPCAGGTQNLPWLVGEGWAKRMILCGERVDAATALRIGLVEEV 180

                 ..
gi 753927005 196 VP 197
Cdd:PRK09076 181 VE 182
PRK06144 PRK06144
enoyl-CoA hydratase; Provisional
24-208 1.03e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180424 [Multi-domain]  Cd Length: 262  Bit Score: 95.06  E-value: 1.03e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFN 102
Cdd:PRK06144  18 IARITFN-RPAARNAMTWAMYEGLAEICEAIAADPSiRAVVLRGAGDKAFVAGTDIAQFRAFSTAEDAVAYERRIDRVLG 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVVdePATKLALPEV-MLGIVPAWGGMKRLPETIGAPAALDLMLTGKSV 181
Cdd:PRK06144  97 ALEQLRVPTIAAIAGACVGGGAAIAAACDLRIAT--PSARFGFPIArTLGNCLSMSNLARLVALLGAARVKDMLFTARLL 174
                        170       180
                 ....*....|....*....|....*..
gi 753927005 182 DARRAKQLGLADECVPPRVMENAARML 208
Cdd:PRK06144 175 EAEEALAAGLVNEVVEDAALDARADAL 201
PRK06494 PRK06494
enoyl-CoA hydratase; Provisional
32-223 1.07e-21

enoyl-CoA hydratase; Provisional


Pssm-ID: 180591 [Multi-domain]  Cd Length: 259  Bit Score: 95.11  E-value: 1.07e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIAS-AKPAGFIAGADIEEftrldspQAARDlvGRGWEL--FNRLVRlR 108
Cdd:PRK06494  21 RPEVMNALHLDAHFELEEVFDDFAADPEQWVAIVTgAGDKAFSAGNDLKE-------QAAGG--KRGWPEsgFGGLTS-R 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 109 F----PTLALIRGHCLGGGLELALACRYrVVVDEPATkLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDAR 184
Cdd:PRK06494  91 FdldkPIIAAVNGVAMGGGFELALACDL-IVAAENAT-FALPEPRVGLAALAGGLHRLPRQIGLKRAMGMILTGRRVTAR 168
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 753927005 185 RAKQLGLADECVPPRVMENAARMLVlsRQRRRKPPLALR 223
Cdd:PRK06494 169 EGLELGFVNEVVPAGELLAAAERWA--DDILACSPLSIR 205
PRK05980 PRK05980
crotonase/enoyl-CoA hydratase family protein;
37-222 1.27e-21

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180335 [Multi-domain]  Cd Length: 260  Bit Score: 94.83  E-value: 1.27e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFT---RLDSPQAARDLVGRGWELFNRLVRLRFPTL 112
Cdd:PRK05980  25 NALNYALIDRLLARLDAIEVDESvRAVILTGAGDRAFSAGADIHEFSasvAAGADVALRDFVRRGQAMTARLEAFPKPVI 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 113 ALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLA 192
Cdd:PRK05980 105 AAVNGLAFGGGCEITEAVHLAIASER--ALFAKPEIRLGMPPTFGGTQRLPRLAGRKRALELLLTGDAFSAERALEIGLV 182
                        170       180       190
                 ....*....|....*....|....*....|
gi 753927005 193 DECVPPRVMENAARmlVLSRQRRRKPPLAL 222
Cdd:PRK05980 183 NAVVPHEELLPAAR--ALARRIIRHSPVAV 210
PRK08252 PRK08252
crotonase/enoyl-CoA hydratase family protein;
32-222 1.02e-20

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181325 [Multi-domain]  Cd Length: 254  Bit Score: 91.98  E-value: 1.02e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPqaarDLVGRGWELFNRlVRLRFPT 111
Cdd:PRK08252  20 RPEARNAVNAAVAQGLAAALDELDADPDLSVGILTGAGGTFCAGMDLKAFARGERP----SIPGRGFGGLTE-RPPRKPL 94
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 112 LALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGL 191
Cdd:PRK08252  95 IAAVEGYALAGGFELALACD--LIVAARDAKFGLPEVKRGLVAAGGGLLRLPRRIPYHIAMELALTGDMLTAERAHELGL 172
                        170       180       190
                 ....*....|....*....|....*....|.
gi 753927005 192 ADECVPPRVMENAArmLVLSRQRRRKPPLAL 222
Cdd:PRK08252 173 VNRLTEPGQALDAA--LELAERIAANGPLAV 201
PRK07066 PRK07066
L-carnitine dehydrogenase;
320-522 3.04e-20

L-carnitine dehydrogenase;


Pssm-ID: 168796 [Multi-domain]  Cd Length: 321  Bit Score: 92.21  E-value: 3.04e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 320 VVGAGVMGGDIAAVCALAGMTVTLQDQAVERIAPAVGRAAKLFERKLRGDTATKARQVRFALDRLIPDphghGARRADVV 399
Cdd:PRK07066  12 AIGSGVIGSGWVARALAHGLDVVAWDPAPGAEAALRANVANAWPALERQGLAPGASPARLRFVATIEA----CVADADFI 87
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 400 IEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYR 479
Cdd:PRK07066  88 QESAPEREALKLELHERISRAAKPDAIIASSTSGLLPTDFYARATHPERCVVGHPFNPVYLLPLVEVLGGERTAPEAVDA 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 753927005 480 AAAFVRRLDKLPLPVR-SAPGFLVNAVLGPYMLEALRCVEEGVA 522
Cdd:PRK07066 168 AMGIYRALGMRPLHVRkEVPGFIADRLLEALWREALHLVNEGVA 211
PRK06127 PRK06127
enoyl-CoA hydratase; Provisional
33-223 5.95e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 235705  Cd Length: 269  Bit Score: 90.15  E-value: 5.95e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  33 DAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWEL-FNRLVRLRFP 110
Cdd:PRK06127  29 PARHNAMSLDMWEALPQALAAAEDDDAiRVVVLTGAGEKAFVSGADISQFEESRSDAEAVAAYEQAVEAaQAALADYAKP 108
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLG 190
Cdd:PRK06127 109 TIACIRGYCIGGGMGIALACDIRIAAED--SRFGIPAARLGLGYGYDGVKNLVDLVGPSAAKDLFYTARRFDAAEALRIG 186
                        170       180       190
                 ....*....|....*....|....*....|...
gi 753927005 191 LADECVPPRVMENAARmlVLSRQRRRKPPLALR 223
Cdd:PRK06127 187 LVHRVTAADDLETALA--DYAATIAGNAPLTLR 217
PRK08138 PRK08138
enoyl-CoA hydratase; Provisional
24-222 6.55e-20

enoyl-CoA hydratase; Provisional


Pssm-ID: 236162 [Multi-domain]  Cd Length: 261  Bit Score: 90.11  E-value: 6.55e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFtrldSPQAARDLVGRGWE-LFN 102
Cdd:PRK08138  18 VALLRLN-RPEARNALNMEVRQQLAEHFTELSEDPDIRAIVLTGGEKVFAAGADIKEF----ATAGAIEMYLRHTErYWE 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK08138  93 AIAQCPKPVIAAVNGYALGGGCELAMHAD--IIVAGESASFGQPEIKVGLMPGAGGTQRLVRAVGKFKAMRMALTGCMVP 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 753927005 183 ARRAKQLGLADECVP-PRVMENAarmLVLSRQRRRKPPLAL 222
Cdd:PRK08138 171 APEALAIGLVSEVVEdEQTLPRA---LELAREIARMPPLAL 208
PRK08150 PRK08150
crotonase/enoyl-CoA hydratase family protein;
24-206 8.79e-19

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181254  Cd Length: 255  Bit Score: 86.61  E-value: 8.79e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPpKGLVIASAKPAgFIAGADIEEFTRLDSPQAARdlVGRGW-ELFN 102
Cdd:PRK08150  12 VATIGLN-RPAKRNALNDGLIAALRAAFARLPEGV-RAVVLHGEGDH-FCAGLDLSELRERDAGEGMH--HSRRWhRVFD 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK08150  87 KIQYGRVPVIAALHGAVVGGGLELASAAHIRVA--DESTYFALPEGQRGIFVGGGGSVRVPRLIGVARMTDMMLTGRVYD 164
                        170       180
                 ....*....|....*....|....*....
gi 753927005 183 ARRAKQLGLADECVPP-----RVMENAAR 206
Cdd:PRK08150 165 AQEGERLGLAQYLVPAgealdKAMELARR 193
PRK03580 PRK03580
crotonobetainyl-CoA hydratase;
33-222 1.23e-18

crotonobetainyl-CoA hydratase;


Pssm-ID: 179599 [Multi-domain]  Cd Length: 261  Bit Score: 86.29  E-value: 1.23e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  33 DAATntlSRAvldeLAAVFAALEAQPPkgLVIASAKPAG---FIAGADIEEFTRLDSPQAARDLVGRG--WELFNrlvrL 107
Cdd:PRK03580  27 DAKT---SFA----MGEVFLNFRDDPE--LRVAIITGAGekfFSAGWDLKAAAEGEAPDADFGPGGFAglTEIFD----L 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 108 RFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAK 187
Cdd:PRK03580  94 DKPVIAAVNGYAFGGGFELALAADFIVCADN--ASFALPEAKLGIVPDSGGVLRLPKRLPPAIANEMVMTGRRMDAEEAL 171
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 753927005 188 QLGLADECVPP-RVMENAARmlvLSRQRRRKPPLAL 222
Cdd:PRK03580 172 RWGIVNRVVPQaELMDRARE---LAQQLVNSAPLAI 204
PLN02888 PLN02888
enoyl-CoA hydratase
32-206 1.66e-18

enoyl-CoA hydratase


Pssm-ID: 215480  Cd Length: 265  Bit Score: 85.96  E-value: 1.66e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADI---EEFTRLDSPQAARDLVGRgwelfnrLVRLR 108
Cdd:PLN02888  27 RPKALNALTRPMMVELAAAFKRLDEDDSVKVIILTGSGRAFCSGVDLtaaEEVFKGDVKDVETDPVAQ-------MERCR 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 109 FPTLALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQ 188
Cdd:PLN02888 100 KPIIGAINGFAITAGFEIALACD--ILVASRGAKFIDTHAKFGIFPSWGLSQKLSRIIGANRAREVSLTAMPLTAETAER 177
                        170
                 ....*....|....*...
gi 753927005 189 LGLADECVPPRVMENAAR 206
Cdd:PLN02888 178 WGLVNHVVEESELLKKAR 195
PRK05869 PRK05869
enoyl-CoA hydratase; Validated
36-222 5.74e-18

enoyl-CoA hydratase; Validated


Pssm-ID: 235632 [Multi-domain]  Cd Length: 222  Bit Score: 83.35  E-value: 5.74e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  36 TNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAA-RDLVGRgwELFNRLVRLRFPTLAL 114
Cdd:PRK05869  28 TNALTRQVYREIVAAANELGRRDDVAAVILYGGHEIFSAGDDMPELRTLSAQEADtAARVRQ--QAVDAVAAIPKPTVAA 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 115 IRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADE 194
Cdd:PRK05869 106 ITGYALGAGLTLALAADWRVSGDN--VKFGATEILAGLAPSGDGMARLTRAAGPSRAKELVFSGRFFDAEEALALGLIDE 183
                        170       180
                 ....*....|....*....|....*...
gi 753927005 195 CVPPRVMENAArmLVLSRQRRRKPPLAL 222
Cdd:PRK05869 184 MVAPDDVYDAA--AAWARRFLDGPPHAL 209
PRK06190 PRK06190
enoyl-CoA hydratase; Provisional
32-208 6.65e-18

enoyl-CoA hydratase; Provisional


Pssm-ID: 235733  Cd Length: 258  Bit Score: 83.87  E-value: 6.65e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRLDSPQAARDlvgRGWELFNRLVRLRFP 110
Cdd:PRK06190  21 RPEARNALSAALRRALFAALAEADADDDvDVVVLTGADPA-FCAGLDLKELGGDGSAYGAQD---ALPNPSPAWPAMRKP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLG 190
Cdd:PRK06190  97 VIGAINGAAVTGGLELALACDILIASER--ARFADTHARVGILPGWGLSVRLPQKVGIGRARRMSLTGDFLDAADALRAG 174
                        170
                 ....*....|....*...
gi 753927005 191 LADECVPPRVMENAARML 208
Cdd:PRK06190 175 LVTEVVPHDELLPRARRL 192
PRK07531 PRK07531
carnitine 3-dehydrogenase;
315-514 1.93e-17

carnitine 3-dehydrogenase;


Pssm-ID: 236044 [Multi-domain]  Cd Length: 495  Bit Score: 85.95  E-value: 1.93e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 315 PRRVHVVGAGVMGGDIAAVCALAGMTVTLQD---QAVERIAPAVGRAAKLFERkLRGDTATKARQVRFALDRlipdphGH 391
Cdd:PRK07531   4 IMKAACIGGGVIGGGWAARFLLAGIDVAVFDphpEAERIIGEVLANAERAYAM-LTDAPLPPEGRLTFCASL------AE 76
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 392 GARRADVVIEAIFENLDAKRALFAQLERRARPDAVLATNTSSLRIEDIGAELANPARLVGIHFFNPVAQMPLVEVVAGEA 471
Cdd:PRK07531  77 AVAGADWIQESVPERLDLKRRVLAEIDAAARPDALIGSSTSGFLPSDLQEGMTHPERLFVAHPYNPVYLLPLVELVGGGK 156
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 753927005 472 SDADALYRAAAFVRRLDKLPLPVRSApgflVNAVLGPYMLEAL 514
Cdd:PRK07531 157 TSPETIRRAKEILREIGMKPVHIAKE----IDAFVGDRLLEAL 195
PRK06142 PRK06142
crotonase/enoyl-CoA hydratase family protein;
37-223 8.55e-17

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235714  Cd Length: 272  Bit Score: 81.17  E-value: 8.55e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAArDLVGRGWELFNRLVR---------- 106
Cdd:PRK06142  28 NAMNPAFWSELPEIFRWLDADPEVRAVVLSGSGKHFSYGIDLPAMAGVFGQLGK-DGLARPRTDLRREILrlqaainava 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 107 -LRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARR 185
Cdd:PRK06142 107 dCRKPVIAAVQGWCIGGGVDLISACDMRYASAD--AKFSVREVDLGMVADVGSLQRLPRIIGDGHLRELALTGRDIDAAE 184
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 753927005 186 AKQLGLADecvppRVMENAARMLVLSRQRRR----KPPLALR 223
Cdd:PRK06142 185 AEKIGLVN-----RVYDDADALLAAAHATAReiaaKSPLAVR 221
PRK09120 PRK09120
p-hydroxycinnamoyl CoA hydratase/lyase; Validated
24-224 9.80e-17

p-hydroxycinnamoyl CoA hydratase/lyase; Validated


Pssm-ID: 236383  Cd Length: 275  Bit Score: 80.82  E-value: 9.80e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHL---DCRDAATNTLSRavldELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTR--LDSPQAARDLVGR-- 96
Cdd:PRK09120  18 IAWVTLnrpEKRNAMSPTLNR----EMIDVLDALEFDDDAGVLVLTGAGDAWSAGMDLKEYFRetDAQPEILQERIRRea 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  97 -GWelFNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLM 175
Cdd:PRK09120  94 yGW--WRRLRWYQKPTIAMVNGWCFGGGFSPLVACDLAIAADE--AQFGLSEINWGIPPGGGVSKAMADTVGHRDALYYI 169
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 753927005 176 LTGKSVDARRAKQLGLADECVP-----PRVMENAARMLvlsrqrrRKPPLALRL 224
Cdd:PRK09120 170 MTGETFTGRKAAEMGLVNESVPlaqlrARTRELAAKLL-------EKNPVVLRA 216
PRK07509 PRK07509
crotonase/enoyl-CoA hydratase family protein;
37-223 3.93e-16

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181008 [Multi-domain]  Cd Length: 262  Bit Score: 78.77  E-value: 3.93e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSpQAARDLVGR--GWE-LFNRLV----RLRF 109
Cdd:PRK07509  25 NALDFAMFEELIATIKRLKKDRGIRAVILSGEGGAFCAGLDVKSVASSPG-NAVKLLFKRlpGNAnLAQRVSlgwrRLPV 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 110 PTLALIRGHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQL 189
Cdd:PRK07509 104 PVIAALEGVCFGGGLQIALGADIRIA--APDTKLSIMEAKWGLVPDMAGTVSLRGLVRKDVARELTYTARVFSAEEALEL 181
                        170       180       190
                 ....*....|....*....|....*....|....*
gi 753927005 190 GLADECVP-PRvmenaARMLVLSRQRRRKPPLALR 223
Cdd:PRK07509 182 GLVTHVSDdPL-----AAALALAREIAQRSPDAIA 211
PLN03214 PLN03214
probable enoyl-CoA hydratase/isomerase; Provisional
37-208 7.06e-16

probable enoyl-CoA hydratase/isomerase; Provisional


Pssm-ID: 215635  Cd Length: 278  Bit Score: 78.38  E-value: 7.06e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPP-KGLVIASA-KPAGFIAGADIEEftrLDSPQAARDLVGRGWELFN----RLVRLRFP 110
Cdd:PLN03214  33 NSMTLAMWRSLDDALTALENDPTvRGVVFASGlRRDVFTAGNDIAE---LYAPKTSAARYAEFWLTQTtflvRLLRSRLA 109
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEPAtkLALPEVMLGI-VPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQL 189
Cdd:PLN03214 110 TVCAIRGACPAGGCAVSLCCDYRLQTTEGT--MGLNEVALGIpVPKFWARLFMGRVIDRKVAESLLLRGRLVRPAEAKQL 187
                        170       180
                 ....*....|....*....|
gi 753927005 190 GLADECVPP-RVMENAARML 208
Cdd:PLN03214 188 GLIDEVVPAaALMEAAASAM 207
PLN02664 PLN02664
enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase
32-191 4.35e-15

enoyl-CoA hydratase/delta3,5-delta2,4-dienoyl-CoA isomerase


Pssm-ID: 178269 [Multi-domain]  Cd Length: 275  Bit Score: 76.09  E-value: 4.35e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDLvGRGWELFNRLV------ 105
Cdd:PLN02664  25 RPSQRNALSLDFFTEFPKALSSLDQNPNVSVIILSGAGDHFCSGIDLKTLNSISEQSSSGDR-GRSGERLRRKIkflqda 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 106 -----RLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKS 180
Cdd:PLN02664 104 itaieQCRKPVIAAIHGACIGGGVDIVTACDIRYCSED--AFFSVKEVDLAITADLGTLQRLPSIVGYGNAMELALTGRR 181
                        170
                 ....*....|.
gi 753927005 181 VDARRAKQLGL 191
Cdd:PLN02664 182 FSGSEAKELGL 192
PRK08259 PRK08259
crotonase/enoyl-CoA hydratase family protein;
32-198 5.34e-14

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236205  Cd Length: 254  Bit Score: 72.24  E-value: 5.34e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDlvGRGWELFNRLvRLRFPT 111
Cdd:PRK08259  20 RPEVRNAVDGPTAAALADAFRAFDADDAASVAVLWGAGGTFCAGADLKAVGTGRGNRLHPS--GDGPMGPSRM-RLSKPV 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 112 LALIRGHCLGGGLELALACRYRVVvDEPATklalpevmLGI------VPAW-GGMKRLPETIGAPAALDLMLTGKSVDAR 184
Cdd:PRK08259  97 IAAVSGYAVAGGLELALWCDLRVA-EEDAV--------FGVfcrrwgVPLIdGGTVRLPRLIGHSRAMDLILTGRPVDAD 167
                        170
                 ....*....|....
gi 753927005 185 RAKQLGLADECVPP 198
Cdd:PRK08259 168 EALAIGLANRVVPK 181
ECH_2 pfam16113
Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: ...
24-197 1.36e-13

Enoyl-CoA hydratase/isomerase; This family contains a diverse set of enzymes including: enoyl-CoA hydratase, napthoate synthase, carnitate racemase, 3-hydroxybutyryl-CoA dehydratase and dodecanoyl-CoA delta-isomerase. This family differs from pfam00378 in the structure of it's C-terminus.


Pssm-ID: 465024 [Multi-domain]  Cd Length: 331  Bit Score: 72.50  E-value: 1.36e-13
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005   24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLV-IASAKPAGFIAGADIEEFTRL---DSPQAARDLVGRGWE 99
Cdd:pfam16113   1 VGVITLN-RPKALNALNLEMVRALLAALKAWEDDPAVKLVvLKGAGERAFCAGGDVRALYEAakaGGGEAGRDFFREEYR 79
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  100 LFNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDepATKLALPEVMLGIVPAWGG---MKRLPETIGapaaLDLML 176
Cdd:pfam16113  80 LNYLIATYPKPYVALMDGIVMGGGVGLSVHGSFRVVTE--RTRFAMPETAIGLFPDVGGsyfLSRLPGELG----LYLAL 153
                         170       180
                  ....*....|....*....|.
gi 753927005  177 TGKSVDARRAKQLGLADECVP 197
Cdd:pfam16113 154 TGARLNGADALAAGLATHYVP 174
PRK05995 PRK05995
enoyl-CoA hydratase; Provisional
24-198 1.42e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 235664 [Multi-domain]  Cd Length: 262  Bit Score: 71.11  E-value: 1.42e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIE------EFTRLDSPQAARDLVgr 96
Cdd:PRK05995  14 VATVTLN-RPDVRNAFNETVIAELTAAFRALDADDSvRAVVLAGAGKA-FCAGADLNwmkkmaGYSDDENRADARRLA-- 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  97 gwELFNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAwGGMKRLPETIGAPAALDLML 176
Cdd:PRK05995  90 --DMLRAIYRCPKPVIARVHGDAYAGGMGLVAACDIAVAADH--AVFCLSEVRLGLIPA-TISPYVIRAMGERAARRYFL 164
                        170       180
                 ....*....|....*....|..
gi 753927005 177 TGKSVDARRAKQLGLADECVPP 198
Cdd:PRK05995 165 TAERFDAAEALRLGLVHEVVPA 186
PRK09245 PRK09245
crotonase/enoyl-CoA hydratase family protein;
32-224 3.02e-13

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181723  Cd Length: 266  Bit Score: 70.38  E-value: 3.02e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLS-RAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIE-----EFTRLDSPQAARDLVGRGwelFNRLV 105
Cdd:PRK09245  20 RPETRNALSdNDAVDALVAACAAINADRSVRAVILTGAGTAFSSGGNVKdmrarVGAFGGSPADIRQGYRHG---IQRIP 96
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 106 R----LRFPTLALIRGHCLGGGLELALACRYRVVVDepATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSV 181
Cdd:PRK09245  97 LalynLEVPVIAAVNGPAIGAGCDLACMCDIRIASE--TARFAESFVKLGLIPGDGGAWLLPRIIGMARAAEMAFTGDAI 174
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|...
gi 753927005 182 DARRAKQLGLADECVPPRVMENAARmlVLSRQRRRKPPLALRL 224
Cdd:PRK09245 175 DAATALEWGLVSRVVPADQLLPAAR--ALAERIAANPPHALRL 215
PRK06495 PRK06495
enoyl-CoA hydratase/isomerase family protein;
37-224 3.45e-13

enoyl-CoA hydratase/isomerase family protein;


Pssm-ID: 168580 [Multi-domain]  Cd Length: 257  Bit Score: 70.11  E-value: 3.45e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDS-PQAARDLVGRGWELFNRLVRLRFPTLALI 115
Cdd:PRK06495  25 NALSRELRDELIAVFDEISERPDVRVVVLTGAGKVFCAGADLKGRPDVIKgPGDLRAHNRRTRECFHAIRECAKPVIAAV 104
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 116 RGHCLGGGLELALACRYrVVVDEPATkLALPEVMLGIVpawGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADEC 195
Cdd:PRK06495 105 NGPALGAGLGLVASCDI-IVASENAV-FGLPEIDVGLA---GGGKHAMRLFGHSLTRRMMLTGYRVPAAELYRRGVIEAC 179
                        170       180
                 ....*....|....*....|....*....
gi 753927005 196 VPPRVMENAARMlvLSRQRRRKPPLALRL 224
Cdd:PRK06495 180 LPPEELMPEAME--IAREIASKSPLATRL 206
PRK08139 PRK08139
enoyl-CoA hydratase; Validated
32-224 8.04e-13

enoyl-CoA hydratase; Validated


Pssm-ID: 181249  Cd Length: 266  Bit Score: 69.20  E-value: 8.04e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPP-KGLVIASAKPAgFIAGADIEEFTRLDSPQAARDLVGRGWELFNRLVRLRFP 110
Cdd:PRK08139  28 RPQAFNALSEAMLAALQAALDAIAADPSvRVVVLAAAGKA-FCAGHDLKEMRAARGLAYFRALFARCSRVMQAIVALPQP 106
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGI---VPawggMKRLPETIGAPAALDLMLTGKSVDARRAK 187
Cdd:PRK08139 107 VIARVHGIATAAGCQLVASCDLAVAADT--ARFAVPGVNIGLfcsTP----MVALSRNVPRKQAMEMLLTGEFIDAATAR 180
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 753927005 188 QLGLADECVPPRVMENAARMLVlsRQRRRKPPLALRL 224
Cdd:PRK08139 181 EWGLVNRVVPADALDAAVARLA--AVIAAKSPAAVRI 215
PRK07659 PRK07659
enoyl-CoA hydratase; Provisional
24-194 8.06e-13

enoyl-CoA hydratase; Provisional


Pssm-ID: 236073 [Multi-domain]  Cd Length: 260  Bit Score: 68.91  E-value: 8.06e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIaSAKPAGFIAGADIEEFTRLDSPQAARDLVGRGWELFNR 103
Cdd:PRK07659  16 VATIMLN-RPEALNALDEPMLKELLQALKEVAESSAHIVVL-RGNGRGFSAGGDIKMMLSSNDESKFDGVMNTISEIVVT 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRLRFPTLALIRGHCLGGGLELALACRYrVVVDEPAtKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDA 183
Cdd:PRK07659  94 LYTMPKLTISAIHGPAAGLGLSIALTADY-VIADISA-KLAMNFIGIGLIPDGGGHFFLQKRVGENKAKQIIWEGKKLSA 171
                        170
                 ....*....|.
gi 753927005 184 RRAKQLGLADE 194
Cdd:PRK07659 172 TEALDLGLIDE 182
PRK06563 PRK06563
crotonase/enoyl-CoA hydratase family protein;
32-223 1.85e-12

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180625 [Multi-domain]  Cd Length: 255  Bit Score: 67.68  E-value: 1.85e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEF------TRLDSPQAARD---LVGRgwelfn 102
Cdd:PRK06563  16 RPAKRNAFDSAMLDDLALALGEYEADDELRVAVLFAHGEHFTAGLDLADVapklaaGGFPFPEGGIDpwgTVGR------ 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 rlvRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK06563  90 ---RLSKPLVVAVQGYCLTLGIELMLAADIVVAADN--TRFAQLEVQRGILPFGGATLRFPQAAGWGNAMRYLLTGDEFD 164
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 753927005 183 ARRAKQLGLADECVPPRvmENAARMLVLSRQRRRKPPLALR 223
Cdd:PRK06563 165 AQEALRLGLVQEVVPPG--EQLERAIELAERIARAAPLGVQ 203
PRK05870 PRK05870
enoyl-CoA hydratase; Provisional
37-225 3.51e-12

enoyl-CoA hydratase; Provisional


Pssm-ID: 180298  Cd Length: 249  Bit Score: 67.06  E-value: 3.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFtRLDSPQAARDLVGRGWELFNRLVRLRFPTLALIR 116
Cdd:PRK05870  25 NAVTAEMSAQLRAAVAAAEADPDVHALVVTGAGKAFCAGADLTAL-GAAPGRPAEDGLRRIYDGFLAVASCPLPTIAAVN 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 117 GHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADECV 196
Cdd:PRK05870 104 GAAVGAGLNLALAADVRIA--GPKALFDARFQKLGLHPGGGATWMLQRAVGPQVARAALLFGMRFDAEAAVRHGLALMVA 181
                        170       180
                 ....*....|....*....|....*....
gi 753927005 197 PprvmENAARMLVLSRQRRRKPPLALRLM 225
Cdd:PRK05870 182 D----DPVAAALELAAGPAAAPRELVLAT 206
PRK08788 PRK08788
enoyl-CoA hydratase; Validated
40-260 6.53e-12

enoyl-CoA hydratase; Validated


Pssm-ID: 236338  Cd Length: 287  Bit Score: 66.86  E-value: 6.53e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  40 SRAVLDELAAVFAALEAQPPKG------LVIASAKPAGFIAGADIEEFTRL----------DSPQAARDLVGRGWELFNR 103
Cdd:PRK08788  41 NLELLDDIMNLQRAIRQRLDDSglpvdfWVLASDVPGVFNLGGDLALFAELiragdrdallAYARACVDGVHAFHRGFGA 120
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRlrfpTLALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDA 183
Cdd:PRK08788 121 GAI----SIALVQGDALGGGFEAALSHH--TIIAERGAKMGFPEILFNLFPGMGAYSFLARRVGPKLAEELILSGKLYTA 194
                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 753927005 184 RRAKQLGLADECVPPRVMENAARMLVlSRQRRRkpplalrlMNGplksVVADRARKQVASKAPREHYpapYAIVDIW 260
Cdd:PRK08788 195 EELHDMGLVDVLVEDGQGEAAVRTFI-RKSKRK--------LNG----WRAMLRARRRVNPLSLEEL---MDITEIW 255
PRK07110 PRK07110
polyketide biosynthesis enoyl-CoA hydratase; Validated
37-249 2.82e-11

polyketide biosynthesis enoyl-CoA hydratase; Validated


Pssm-ID: 235936  Cd Length: 249  Bit Score: 64.22  E-value: 2.82e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAA-RDLvgrgwELFNRLVRLRFPTLALI 115
Cdd:PRK07110  27 NAFSDELCDQLHEAFDTIAQDPRYKVVILTGYPNYFATGGTQEGLLSLQTGKGTfTEA-----NLYSLALNCPIPVIAAM 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 116 RGHCLGGGLELALACRYRVVVDEP--ATKLAlpevMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLAD 193
Cdd:PRK07110 102 QGHAIGGGLVLGLYADIVVLSRESvyTANFM----KYGFTPGMGATAILPEKLGLALGQEMLLTARYYRGAELKKRGVPF 177
                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*..
gi 753927005 194 ECVP-PRVMENAarmLVLSRQRRRKPPLALRLmngpLKSVVADRARKQVASKAPREH 249
Cdd:PRK07110 178 PVLPrAEVLEKA---LELARSLAEKPRHSLVL----LKDHLVADRRRRLPEVIEQEV 227
PRK11423 PRK11423
methylmalonyl-CoA decarboxylase; Provisional
37-225 2.89e-11

methylmalonyl-CoA decarboxylase; Provisional


Pssm-ID: 236908 [Multi-domain]  Cd Length: 261  Bit Score: 64.28  E-value: 2.89e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASakPAG---FIAGADIEEFtrldsPQAARDLVGRG--WELFNRLVRlRF-- 109
Cdd:PRK11423  26 NALSKVLIDDLMQALSDLNRPEIRVVILRA--PSGskvWSAGHDIHEL-----PSGGRDPLSYDdpLRQILRMIQ-KFpk 97
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 110 PTLALIRGHCLGGGLELALACryRVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQL 189
Cdd:PRK11423  98 PVIAMVEGSVWGGAFELIMSC--DLIIAASTSTFAMTPANLGVPYNLSGILNFTNDAGFHIVKEMFFTASPITAQRALAV 175
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 753927005 190 GLADECVPPRVMENAARMlvLSRQRRRKPPLALRLM 225
Cdd:PRK11423 176 GILNHVVEVEELEDFTLQ--MAHHISEKAPLAIAVI 209
PRK06213 PRK06213
crotonase/enoyl-CoA hydratase family protein;
24-206 4.46e-11

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 235744  Cd Length: 229  Bit Score: 63.07  E-value: 4.46e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcrDAATNTLSRAVLDELAAVFAALEAQppKGLVIASAKPAGFIAGADIEEFTRldSPQAARDLVGRGWELFNR 103
Cdd:PRK06213  13 VATITLD--DGKVNALSPAMIDALNAALDQAEDD--RAVVVITGQPGIFSGGFDLKVMTS--GAQAAIALLTAGSTLARR 86
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPaTKLALPEVMLGIVPAWGGMK----RLpetigAPAALD-LMLTG 178
Cdd:PRK06213  87 LLSHPKPVIVACTGHAIAKGAFLLLSADYRIGVHGP-FKIGLNEVAIGMTMPHAAIElardRL-----TPSAFQrAVINA 160
                        170       180
                 ....*....|....*....|....*...
gi 753927005 179 KSVDARRAKQLGLADECVPPRVMENAAR 206
Cdd:PRK06213 161 EMFDPEEAVAAGFLDEVVPPEQLLARAQ 188
PRK05674 PRK05674
gamma-carboxygeranoyl-CoA hydratase; Validated
27-205 3.73e-10

gamma-carboxygeranoyl-CoA hydratase; Validated


Pssm-ID: 168168  Cd Length: 265  Bit Score: 60.98  E-value: 3.73e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  27 LHLDCRDAATNTLSRA---------VLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADI---EEFTRLD---SPQAAR 91
Cdd:PRK05674   9 LIRDPRGFATLWLSRAdknnafnaqMIRELILALDQVQSDASLRFLLLRGRGRHFSAGADLawmQQSADLDyntNLDDAR 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  92 DLVgrgwELFNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGmKRLPETIGAPAA 171
Cdd:PRK05674  89 ELA----ELMYNLYRLKIPTLAVVQGAAFGGALGLISCCDMAIGADD--AQFCLSEVRIGLAPAVIS-PFVVKAIGERAA 161
                        170       180       190
                 ....*....|....*....|....*....|....
gi 753927005 172 LDLMLTGKSVDARRAKQLGLADECVPPRVMENAA 205
Cdd:PRK05674 162 RRYALTAERFDGRRARELGLLAESYPAAELEAQV 195
PRK06210 PRK06210
enoyl-CoA hydratase; Provisional
46-218 4.02e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 180472  Cd Length: 272  Bit Score: 61.26  E-value: 4.02e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  46 ELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARD-----LVG----RGWELFNRLVRLRFPTLALIR 116
Cdd:PRK06210  37 EVYAAMDRAEADPAVRVIVLTGAGRGFCAGADMGELQTIDPSDGRRDtdvrpFVGnrrpDYQTRYHFLTALRKPVIAAIN 116
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 117 GHCLGGGLELALACRYRVVVDEPATKLALPEvmLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADECV 196
Cdd:PRK06210 117 GACAGIGLTHALMCDVRFAADGAKFTTAFAR--RGLIAEHGISWILPRLVGHANALDLLLSARTFYAEEALRLGLVNRVV 194
                        170       180       190
                 ....*....|....*....|....*....|....*.
gi 753927005 197 PP-RVMENA-------------ARMLVLSRQRRRKP 218
Cdd:PRK06210 195 PPdELMERTlayaedlarnvspASMAVIKRQLYEDA 230
PRK05864 PRK05864
enoyl-CoA hydratase; Provisional
63-212 7.99e-10

enoyl-CoA hydratase; Provisional


Pssm-ID: 168278 [Multi-domain]  Cd Length: 276  Bit Score: 60.23  E-value: 7.99e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  63 VIASAKPAGFIAGAD------IEEFTRLDSPQAARdlvgRGWELFNRLV----RLRFPTLALIRGHCLGGGLELALACRY 132
Cdd:PRK05864  58 VVLTGAGRGFSSGADhksagvVPHVEGLTRPTYAL----RSMELLDDVIlalrRLHQPVIAAVNGPAIGGGLCLALAADI 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 133 RVVVDEPATKLAlpEVMLGIVPAWGGMKRL-PETIGAPAALDLMLTGKSVDARRAKQLGLADECVP-----PRVMENAAR 206
Cdd:PRK05864 134 RVASSSAYFRAA--GINNGLTASELGLSYLlPRAIGSSRAFEIMLTGRDVDAEEAERIGLVSRQVPdeqllDTCYAIAAR 211

                 ....*.
gi 753927005 207 MLVLSR 212
Cdd:PRK05864 212 MAGFSR 217
PRK07468 PRK07468
crotonase/enoyl-CoA hydratase family protein;
24-198 9.96e-10

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 180987 [Multi-domain]  Cd Length: 262  Bit Score: 59.69  E-value: 9.96e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIE------EFTRLDSPQAARDLVgrg 97
Cdd:PRK07468  15 VATLTLN-RPEKHNALSARMIAELTTAARRLAADAAVRVVVLTGAGKSFCAGGDLGwmraqmTADRATRIEEARRLA--- 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  98 wELFNRLVRLRFPTLALIRGHCLGGGLELALACryRVVVDEPATKLALPEVMLGIVPAWGGMKRLPEtIGAPAALDLMLT 177
Cdd:PRK07468  91 -MMLKALNDLPKPLIGRIQGQAFGGGVGLISVC--DVAIAVSGARFGLTETRLGLIPATISPYVVAR-MGEANARRVFMS 166
                        170       180
                 ....*....|....*....|.
gi 753927005 178 GKSVDARRAKQLGLADECVPP 198
Cdd:PRK07468 167 ARLFDAEEAVRLGLLSRVVPA 187
PRK08290 PRK08290
enoyl-CoA hydratase; Provisional
24-225 1.67e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236220 [Multi-domain]  Cd Length: 288  Bit Score: 59.59  E-value: 1.67e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRL--------DSPQAARDLVG 95
Cdd:PRK08290  14 IARITLN-RPEARNAQNRQMLYELDAAFRRAEADDAVRVIVLAGAGKHFSAGHDLGSGTPGrdrdpgpdQHPTLWWDGAT 92
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  96 RG---------WELFNRLVR----LRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIvpawGGMKRL 162
Cdd:PRK08290  93 KPgveqryareWEVYLGMCRrwrdLPKPTIAQVQGACIAGGLMLAWVCDLIVASDD--AFFSDPVVRMGI----PGVEYF 166
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 753927005 163 --PETIGAPAALDLMLTGKSVDARRAKQLGLADECVPPRvmENAARMLVLSRQRRRKPPLALRLM 225
Cdd:PRK08290 167 ahPWELGPRKAKELLFTGDRLTADEAHRLGMVNRVVPRD--ELEAETLELARRIAAMPPFGLRLT 229
PRK07827 PRK07827
enoyl-CoA hydratase family protein;
37-191 1.90e-09

enoyl-CoA hydratase family protein;


Pssm-ID: 236109 [Multi-domain]  Cd Length: 260  Bit Score: 58.93  E-value: 1.90e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFT--RLDSPQAARDLVGRGWELFNRLVRLRFPTLAL 114
Cdd:PRK07827  28 NALSARLVAQLHDGLRAAAADPAVRAVVLTHTGGTFCAGADLSEAGggGGDPYDAAVARAREMTALLRAIVELPKPVIAA 107
                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 753927005 115 IRGHCLGGGLELALACryRVVVDEPATKLALPEVMLGIVPAWGGMKRLPEtIGAPAALDLMLTGKSVDARRAKQLGL 191
Cdd:PRK07827 108 IDGHVRAGGFGLVGAC--DIVVAGPESTFALTEARIGVAPAIISLTLLPR-LSPRAAARYYLTGEKFGAAEAARIGL 181
PRK07854 PRK07854
enoyl-CoA hydratase; Provisional
32-194 6.51e-09

enoyl-CoA hydratase; Provisional


Pssm-ID: 236115 [Multi-domain]  Cd Length: 243  Bit Score: 56.96  E-value: 6.51e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAgFIAGADieeftrLDSPQAARDLVGRGWELFNRLVRLRFPT 111
Cdd:PRK07854  17 RPERRNALNAELCEELREAVRKAVDESARAIVLTGQGTV-FCAGAD------LSGDVYADDFPDALIEMLHAIDAAPVPV 89
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 112 LALIRGHCLGGGLELALACRYRVVVDEPAtkLALPEVMLGI-VPAWgGMKRLPETIGAPAALDLMLTGKSVDARRAKQLG 190
Cdd:PRK07854  90 IAAINGPAIGAGLQLAMACDLRVVAPEAY--FQFPVAKYGIaLDNW-TIRRLSSLVGGGRARAMLLGAEKLTAEQALATG 166

                 ....
gi 753927005 191 LADE 194
Cdd:PRK07854 167 MANR 170
PRK07799 PRK07799
crotonase/enoyl-CoA hydratase family protein;
32-197 9.47e-09

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 181122 [Multi-domain]  Cd Length: 263  Bit Score: 57.03  E-value: 9.47e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDlvgRGWELFN-----RLVR 106
Cdd:PRK07799  22 RPEARNALSTEMLRIMVDAWDRVDNDPDIRSCILTGAGGAFCAGMDLKAATKKPPGDSFKD---GSYDPSRidallKGRR 98
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 107 LRFPTLALIRGHCLGGGLELALACRYRVVVDepATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRA 186
Cdd:PRK07799  99 LTKPLIAAVEGPAIAGGTEILQGTDIRVAGE--SAKFGISEAKWSLFPMGGSAVRLVRQIPYTVACDLLLTGRHITAAEA 176
                        170
                 ....*....|.
gi 753927005 187 KQLGLADECVP 197
Cdd:PRK07799 177 KEIGLIGHVVP 187
PRK08140 PRK08140
enoyl-CoA hydratase; Provisional
37-225 2.05e-08

enoyl-CoA hydratase; Provisional


Pssm-ID: 236163  Cd Length: 262  Bit Score: 55.69  E-value: 2.05e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKpAGFIAGADIEEfTRLDSPQAARDLVGRGWELFNRLVR----LRFPTL 112
Cdd:PRK08140  26 NSFTREMHRELREALDQVEDDGARALLLTGAG-RGFCAGQDLAD-RDVTPGGAMPDLGESIETFYNPLVRrlraLPLPVI 103
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 113 ALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLA 192
Cdd:PRK08140 104 AAVNGVAAGAGANLALACD--IVLAARSASFIQAFVKIGLVPDSGGTWFLPRLVGMARALGLALLGEKLSAEQAEQWGLI 181
                        170       180       190
                 ....*....|....*....|....*....|....
gi 753927005 193 DECVP-PRVMENAARmlvLSRQRRRKPPLALRLM 225
Cdd:PRK08140 182 WRVVDdAALADEAQQ---LAAHLATQPTRGLALI 212
PRK08272 PRK08272
crotonase/enoyl-CoA hydratase family protein;
37-207 2.41e-08

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 236213  Cd Length: 302  Bit Score: 56.20  E-value: 2.41e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEF-----------TRLDSPQAARDLVGRGW------- 98
Cdd:PRK08272  32 NAITADTPLELRAAVERADLDPGVHVILVSGAGKGFCAGYDLSAYaegsssgggggAYPGKRQAVNHLPDDPWdpmidyq 111
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  99 ------ELFNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAwGGM--KRLpetiGAPA 170
Cdd:PRK08272 112 mmsrfvRGFMSLWHAHKPTVAKVHGYCVAGGTDIALHCDQVIAADD--AKIGYPPTRVWGVPA-TGMwaYRL----GPQR 184
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 753927005 171 ALDLMLTGKSVDARRAKQLGLADECVPP-----RVMENAARM 207
Cdd:PRK08272 185 AKRLLFTGDCITGAQAAEWGLAVEAVPPeeldeRTERLVERI 226
PRK05617 PRK05617
3-hydroxyisobutyryl-CoA hydrolase; Provisional
32-197 1.50e-07

3-hydroxyisobutyryl-CoA hydrolase; Provisional


Pssm-ID: 235533 [Multi-domain]  Cd Length: 342  Bit Score: 54.06  E-value: 1.50e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLV-IASAKPAGFIAGADIEEFTRLDS---PQAARDLVGRGWELFNRLVRL 107
Cdd:PRK05617  20 RPKALNALSLEMIRAIDAALDAWEDDDAVAAVvIEGAGERGFCAGGDIRALYEAARagdPLAADRFFREEYRLNALIARY 99
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 108 RFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGApAALDLMLTGKSVDARRAK 187
Cdd:PRK05617 100 PKPYIALMDGIVMGGGVGISAHGSHRIVTER--TKMAMPETGIGFFPDVGGTYFLSRAPGA-LGTYLALTGARISAADAL 176
                        170
                 ....*....|
gi 753927005 188 QLGLADECVP 197
Cdd:PRK05617 177 YAGLADHFVP 186
PLN02874 PLN02874
3-hydroxyisobutyryl-CoA hydrolase-like protein
37-211 3.95e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178462 [Multi-domain]  Cd Length: 379  Bit Score: 52.88  E-value: 3.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRL-DSPQAARDLVGRGWELFNRLVRLRFPTLALI 115
Cdd:PLN02874  33 NVISLSVVSLLAEFLEQWEKDDSVELIIIKGAGRAFSAGGDLKMFYDGrESDDSCLEVVYRMYWLCYHIHTYKKTQVALV 112
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 116 RGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGG---MKRLPETIGAPaaldLMLTGKSVDARRAKQLGLA 192
Cdd:PLN02874 113 HGLVMGGGAGLMVPMKFRVVTEK--TVFATPEASVGFHTDCGFsyiLSRLPGHLGEY----LALTGARLNGKEMVACGLA 186
                        170       180
                 ....*....|....*....|
gi 753927005 193 DECVP-PRVMENAARMLVLS 211
Cdd:PLN02874 187 THFVPsEKLPELEKRLLNLN 206
PRK07112 PRK07112
enoyl-CoA hydratase/isomerase;
24-226 4.96e-07

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235938  Cd Length: 255  Bit Score: 51.61  E-value: 4.96e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPkgLVIASAKPAGFIAGADIEE-FTRLDSPQAARDLVGRGWELFN 102
Cdd:PRK07112  14 VCFLQLH-RPEAQNTINDRLIAECMDVLDRCEHAAT--IVVLEGLPEVFCFGADFSAiAEKPDAGRADLIDAEPLYDLWH 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 RLVRLRFPTLALIRGHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWgGMKRLPETIGAPAALDLMLTGKSVD 182
Cdd:PRK07112  91 RLATGPYVTIAHVRGKVNAGGIGFVAASD--IVIADETAPFSLSELLFGLIPAC-VLPFLIRRIGTQKAHYMTLMTQPVT 167
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 753927005 183 ARRAKQLGLADECVPprvmeNAARMLV--LSRQRRRKPPLALRLMN 226
Cdd:PRK07112 168 AQQAFSWGLVDAYGA-----NSDTLLRkhLLRLRCLNKAAVARYKS 208
PRK07938 PRK07938
enoyl-CoA hydratase family protein;
46-224 5.16e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 181174  Cd Length: 249  Bit Score: 51.51  E-value: 5.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  46 ELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSPQAARDlVGRG-WELFNRLVRLRFPTLALIRGHCLGGGL 124
Cdd:PRK07938  32 ALADAITAAGADPDTRVVVLRAEGRGFNAGVDIKELQATPGFTALID-ANRGcFAAFRAVYECAVPVIAAVHGFCLGGGI 110
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 125 ELALACryRVVVDEPATKLALPEVMLGivpAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADECVPPRVMENA 204
Cdd:PRK07938 111 GLVGNA--DVIVASDDATFGLPEVDRG---ALGAATHLQRLVPQHLMRALFFTAATITAAELHHFGSVEEVVPRDQLDEA 185
                        170       180
                 ....*....|....*....|
gi 753927005 205 ArmLVLSRQRRRKPPLALRL 224
Cdd:PRK07938 186 A--LEVARKIAAKDTRVIRA 203
PRK06023 PRK06023
crotonase/enoyl-CoA hydratase family protein;
37-234 7.20e-07

crotonase/enoyl-CoA hydratase family protein;


Pssm-ID: 168351  Cd Length: 251  Bit Score: 50.95  E-value: 7.20e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFtrLDSPQAARDLVGRGWELFNRLVRLRFPTLALIR 116
Cdd:PRK06023  28 NAITRAMYATMAKALKAADADDAIRAHVFLGTEGCFSAGNDMQDF--LAAAMGGTSFGSEILDFLIALAEAEKPIVSGVD 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 117 GHCLGGGLELALACRyrVVVDEPATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKSVDARRAKQLGLADECV 196
Cdd:PRK06023 106 GLAIGIGTTIHLHCD--LTFASPRSLFRTPFVDLALVPEAGSSLLAPRLMGHQRAFALLALGEGFSAEAAQEAGLIWKIV 183
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|..
gi 753927005 197 PPRVMEnaARMLVLSRQRRRKPPLALR----LMNGPLKSVVA 234
Cdd:PRK06023 184 DEEAVE--AETLKAAEELAAKPPQALQiardLMRGPREDILA 223
PRK08258 PRK08258
enoyl-CoA hydratase family protein;
46-228 8.78e-07

enoyl-CoA hydratase family protein;


Pssm-ID: 181329  Cd Length: 277  Bit Score: 51.12  E-value: 8.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  46 ELAAVFAALE-AQPPKGLVIASAKPaGFIAGAD----IEEFTRLDSPqaardlvgrgwEL--FNR----LVR----LRFP 110
Cdd:PRK08258  48 ELRDLFRELVyADDVKAVVLTGAGG-NFCSGGDvheiIGPLTKMDMP-----------ELlaFTRmtgdLVKamraCPQP 115
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 111 TLALIRGHCLGGGLELALACRYRVVVdePATKLALPEVMLGIVPA-WGGMKRLPETIGAPAALDLMLTGKSVDARRAKQL 189
Cdd:PRK08258 116 IIAAVDGVCAGAGAILAMASDLRLGT--PSAKTAFLFTRVGLAGAdMGACALLPRIIGQGRASELLYTGRSMSAEEGERW 193
                        170       180       190
                 ....*....|....*....|....*....|....*....
gi 753927005 190 GLADECVPPRVMENAARmlvlsrqrrrkpPLALRLMNGP 228
Cdd:PRK08258 194 GFFNRLVEPEELLAEAQ------------ALARRLAAGP 220
PLN02851 PLN02851
3-hydroxyisobutyryl-CoA hydrolase-like protein
32-192 9.68e-07

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 178443 [Multi-domain]  Cd Length: 407  Bit Score: 51.52  E-value: 9.68e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRLDSpQAARDLVGRGWELFNRLVRLR--- 108
Cdd:PLN02851  59 RPSSLNALTIPMVARLKRLYESWEENPDIGFVLMKGSGRAFCSGADVVSLYHLIN-EGNVEECKLFFENLYKFVYLQgty 137
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 109 -FPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGG---MKRLPETIGAPaaldLMLTGKSVDAR 184
Cdd:PLN02851 138 lKPNVAIMDGITMGCGAGISIPGMFRVVTDK--TVFAHPEVQMGFHPDAGAsyyLSRLPGYLGEY----LALTGQKLNGV 211

                 ....*...
gi 753927005 185 RAKQLGLA 192
Cdd:PLN02851 212 EMIACGLA 219
PLN02157 PLN02157
3-hydroxyisobutyryl-CoA hydrolase-like protein
32-209 2.97e-06

3-hydroxyisobutyryl-CoA hydrolase-like protein


Pssm-ID: 177817 [Multi-domain]  Cd Length: 401  Bit Score: 50.07  E-value: 2.97e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRL---DSPQAARDLVGRGWELFNRLVRLR 108
Cdd:PLN02157  54 RPPALNALTTHMGYRLQKLYKNWEEDPNIGFVMMKGSGRAFCAGGDIVSLYHLrkrGSPDAIREFFSSLYSFIYLLGTYL 133
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 109 FPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGG---MKRLPETIGAPaaldLMLTGKSVDARR 185
Cdd:PLN02157 134 KPHVAILNGVTMGGGTGVSIPGTFRVATDR--TIFATPETIIGFHPDAGAsfnLSHLPGRLGEY----LGLTGLKLSGAE 207
                        170       180
                 ....*....|....*....|....*....
gi 753927005 186 AKQLGLA-----DECVPprVMENAARMLV 209
Cdd:PLN02157 208 MLACGLAthyirSEEIP--VMEEQLKKLL 234
PRK06072 PRK06072
enoyl-CoA hydratase; Provisional
37-237 3.19e-06

enoyl-CoA hydratase; Provisional


Pssm-ID: 168377 [Multi-domain]  Cd Length: 248  Bit Score: 49.01  E-value: 3.19e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFtrldSPQAARDLVgrgwELFNRLVR-LRFPT---L 112
Cdd:PRK06072  22 NALNLEMRNEFISKLKQINADPKIRVVIVTGEGRAFCVGADLSEF----APDFAIDLR----ETFYPIIReIRFSDkiyI 93
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 113 ALIRGHCLGGGLELALACRYRVVvdEPATKLALPEVMLGIVPAWGGMKRLPETIGApAALDLMLTGKSVDARRAKQLGLA 192
Cdd:PRK06072  94 SAINGVTAGACIGIALSTDFKFA--SRDVKFVTAFQRLGLASDTGVAYFLLKLTGQ-RFYEILVLGGEFTAEEAERWGLL 170
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*
gi 753927005 193 decvppRVMENAarmlvLSRQRRrkppLALRLMNGPLKSVVADRA 237
Cdd:PRK06072 171 ------KISEDP-----LSDAEE----MANRISNGPFQSYIAAKR 200
PLN02988 PLN02988
3-hydroxyisobutyryl-CoA hydrolase
32-197 4.32e-06

3-hydroxyisobutyryl-CoA hydrolase


Pssm-ID: 178568 [Multi-domain]  Cd Length: 381  Bit Score: 49.33  E-value: 4.32e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  32 RDAATNTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADIEEFTRlDSPQAARDLvgrGWELFNRLVRLRF-- 109
Cdd:PLN02988  26 RPKQLNALSFHMISRLLQLFLAFEEDPSVKLVILKGHGRAFCAGGDVAAVVR-DIEQGNWRL---GANFFSDEYMLNYvm 101
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 110 -----PTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGG---MKRLPETIGAPAAldlmLTGKSV 181
Cdd:PLN02988 102 atyskAQVSILNGIVMGGGAGVSVHGRFRIATEN--TVFAMPETALGLFPDVGAsyfLSRLPGFFGEYVG----LTGARL 175
                        170
                 ....*....|....*.
gi 753927005 182 DARRAKQLGLADECVP 197
Cdd:PLN02988 176 DGAEMLACGLATHFVP 191
PRK05981 PRK05981
enoyl-CoA hydratase/isomerase;
24-236 2.02e-05

enoyl-CoA hydratase/isomerase;


Pssm-ID: 235661  Cd Length: 266  Bit Score: 46.65  E-value: 2.02e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  24 VAWLHLDcRDAATNTLSRAVLDELAAVFAALEAQPPKG-LVIASAKPAGFIAGADIEefTRLDSPQAARDLVGRGWEL-- 100
Cdd:PRK05981  14 VAILTLD-HPEVMNAVSIDMLGGLAEALDAIEDGKAEVrCLVLTGAGRGFCTGANLQ--GRGSGGRESDSGGDAGAALet 90
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 101 -FNRLVR----LRFPTLALIRGHCLGGGLELALACRYRVVVDEPATKLALPEVmlGIVPAWGGMKRLPETIGAPAALDLM 175
Cdd:PRK05981  91 aYHPFLRrlrnLPCPIVTAVNGPAAGVGMSFALMGDLILCARSAYFLQAFRRI--GLVPDGGSTWLLPRLVGKARAMELS 168
                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 753927005 176 LTGKSVDARRAKQLGLADECVP-PRVMENAARmlvlsrqrrrkppLALRLMNGPLKSVVADR 236
Cdd:PRK05981 169 LLGEKLPAETALQWGLVNRVVDdAELMAEAMK-------------LAHELANGPTVALGLIR 217
PLN02267 PLN02267
enoyl-CoA hydratase/isomerase family protein
104-193 3.11e-05

enoyl-CoA hydratase/isomerase family protein


Pssm-ID: 215151  Cd Length: 239  Bit Score: 45.86  E-value: 3.11e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 104 LVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEPATkLALPEVMLG-IVPAWgGMKRLPETIGAPAAL-DLMLTGKSV 181
Cdd:PLN02267  90 LISLPMPTIAAVTGHASAAGFILALSHDYVLMRKDRGV-LYMSEVDIGlPLPDY-FMALLRAKIGSPAARrDVLLRAAKL 167
                         90
                 ....*....|..
gi 753927005 182 DARRAKQLGLAD 193
Cdd:PLN02267 168 TAEEAVEMGIVD 179
PRK08260 PRK08260
enoyl-CoA hydratase; Provisional
37-225 1.77e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 236206 [Multi-domain]  Cd Length: 296  Bit Score: 43.84  E-value: 1.77e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  37 NTLSRAVLDELAAVFAALEAQPPKGLVIASAKPAGFIAGADI--------EEFTRLDSPQAARDLVGR--------GWEL 100
Cdd:PRK08260  26 NAFTVTMARELIEAFDAADADDAVRAVIVTGAGRAFCAGADLsaggntfdLDAPRTPVEADEEDRADPsddgvrdgGGRV 105
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 101 FNRLVRLRFPTLALIRGHCLGGGLELALACRYRVVVDepATKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTGKS 180
Cdd:PRK08260 106 TLRIFDSLKPVIAAVNGPAVGVGATMTLAMDIRLAST--AARFGFVFGRRGIVPEAASSWFLPRLVGLQTALEWVYSGRV 183
                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*...
gi 753927005 181 VDARRAKQLGLADECVPPRVMENAARMLVLSRQRRRKPP---LALRLM 225
Cdd:PRK08260 184 FDAQEALDGGLVRSVHPPDELLPAARALAREIADNTSPVsvaLTRQMM 231
PRK07260 PRK07260
enoyl-CoA hydratase; Provisional
33-215 3.44e-04

enoyl-CoA hydratase; Provisional


Pssm-ID: 180910 [Multi-domain]  Cd Length: 255  Bit Score: 42.80  E-value: 3.44e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005  33 DAATNTLSR---------AVLDE-LAAVFAALEAQPPKGLVIaSAKPAGFIAGADIEEFTRLDSPQAARDLVgRGWELFN 102
Cdd:PRK07260  11 DLATLTLNRpevsngfniPMCQEiLEALRLAEEDPSVRFLLI-NANGKVFSVGGDLVEMKRAVDEDDVQSLV-KIAELVN 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 103 R----LVRLRFPTLALIRGHCLGGGLELALACRYRVVVDEpaTKLALPEVMLGIVPAWGGMKRLPETIGAPAALDLMLTG 178
Cdd:PRK07260  89 EisfaIKQLPKPVIMCVDGAVAGAAANMAVAADFCIASTK--TKFIQAFVGVGLAPDAGGLFLLTRAIGLNRATHLAMTG 166
                        170       180       190
                 ....*....|....*....|....*....|....*..
gi 753927005 179 KSVDARRAKQLGLADECVPPRVMENAARMLvLSRQRR 215
Cdd:PRK07260 167 EALTAEKALEYGFVYRVAESEKLEKTCEQL-LKKLRR 202
PRK08268 PRK08268
3-hydroxy-acyl-CoA dehydrogenase; Validated
440-549 2.85e-03

3-hydroxy-acyl-CoA dehydrogenase; Validated


Pssm-ID: 236211 [Multi-domain]  Cd Length: 507  Bit Score: 40.60  E-value: 2.85e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 753927005 440 GAELANPARLVGIHFFNPVAQMPLVEVVAGEASDADALYRAAAFVRRLDKLPLPVRSAPGFLVNAVLGpyML--EALRCV 517
Cdd:PRK08268 357 AREGLDAARVVLIDLLLDYAAAKRRTLMAAPATSPAARDAAHALFQQDGKAVSVIRDSPGFVAQRTVA--MIvnEAADIA 434
                         90       100       110
                 ....*....|....*....|....*....|....*
gi 753927005 518 EEGVA-PEAVDAAlVAFGM--PMGPVELVDTVGLD 549
Cdd:PRK08268 435 QQGIAsPADIDLA-MRLGLnyPLGPLAWGDRLGAA 468
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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