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Conserved domains on  [gi|749385045|ref|NP_001291318|]
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leucine-rich repeat and transmembrane domain-containing protein 1 isoform 2 [Homo sapiens]

Protein Classification

leucine-rich repeat domain-containing protein( domain architecture ID 12156429)

leucine-rich repeat (LRR) domain-containing protein may participate in protein-protein interactions; similar to Homo sapiens trophoblast glycoprotein-like and Mus musculus leucine-rich repeat-containing protein 52

Gene Ontology:  GO:0005515
PubMed:  11751054|14747988

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
15-58 1.65e-11

Leucine rich repeat;


:

Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.30  E-value: 1.65e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 749385045   15 PGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNI 58
Cdd:pfam13855  18 DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR super family cl34836
Leucine-rich repeat (LRR) protein [Transcription];
15-104 7.58e-11

Leucine-rich repeat (LRR) protein [Transcription];


The actual alignment was detected with superfamily member COG4886:

Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 7.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  15 PGAFHGLQHLQVLNLTQNSLLSLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMP 94
Cdd:COG4886  152 PEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLT 228

                         90
                 ....*....|
gi 749385045  95 SVRLLLLKDN 104
Cdd:COG4886  229 NLETLDLSNN 238
LRRCT super family cl47026
Leucine rich repeat C-terminal domain;
104-157 7.25e-03

Leucine rich repeat C-terminal domain;


The actual alignment was detected with superfamily member smart00082:

Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 33.94  E-value: 7.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 749385045   104 NLWKCNCHLLGLKLWLEKFVYKGGlTDGIICESPDTWKGKdLLRIPHELyQPCP 157
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQD-PVDLRCASPSSLRGP-LLELLHSE-FKCP 51
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
15-58 1.65e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.30  E-value: 1.65e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 749385045   15 PGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNI 58
Cdd:pfam13855  18 DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-104 7.58e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 7.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  15 PGAFHGLQHLQVLNLTQNSLLSLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMP 94
Cdd:COG4886  152 PEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLT 228

                         90
                 ....*....|
gi 749385045  95 SVRLLLLKDN 104
Cdd:COG4886  229 NLETLDLSNN 238
LRR_8 pfam13855
Leucine rich repeat;
46-105 6.21e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.29  E-value: 6.21e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045   46 PQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNL 105
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 24-80 5.79e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 5.79e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 749385045  24 LQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLP--TSLGETWENLTILAVQQN 80
Cdd:cd21340  122 LRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGN 178
PLN03150 PLN03150
hypothetical protein; Provisional
 21-82 3.73e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.73  E-value: 3.73e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 749385045  21 LQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLGETwENLTILAVQQNQL 82
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQL-TSLRILNLNGNSL 502
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 18-104 2.56e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 38.23  E-value: 2.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  18 FHGLQHLQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNI---------SHLPTSLGETwenLTILAVQQNQLQQLDra 88
Cdd:cd21340   64 LENLVNLKKLYLGGNRISVVEG--LENLTNLEELHIENQRLppgekltfdPRSLAALSNS---LRVLNISGNNIDSLE-- 136

                         90
                 ....*....|....*.
gi 749385045  89 LLESMPSVRLLLLKDN 104
Cdd:cd21340  137 PLAPLRNLEQLDASNN 152
LRR smart00370
Leucine-rich repeats, outliers;
45-62 2.66e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.66e-03
                           10
                   ....*....|....*...
gi 749385045    45 LPQLRELDLSSNNISHLP 62
Cdd:smart00370   1 LPNLRELDLSNNQLSSLP 18
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 18-104 5.61e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 37.91  E-value: 5.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  18 FHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLgETWENLTILAVQQNQLQQLDRALLESMPSV 96
Cdd:PLN00113 471 SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDEL-SSCKKLVSLDLSHNQLSGQIPASFSEMPVL 549


                 ....*...
gi 749385045  97 RLLLLKDN 104
Cdd:PLN00113 550 SQLDLSQN 557
LRRCT smart00082
Leucine rich repeat C-terminal domain;
104-157 7.25e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 33.94  E-value: 7.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 749385045   104 NLWKCNCHLLGLKLWLEKFVYKGGlTDGIICESPDTWKGKdLLRIPHELyQPCP 157
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQD-PVDLRCASPSSLRGP-LLELLHSE-FKCP 51
 
Name Accession Description Interval E-value
LRR_8 pfam13855
Leucine rich repeat;
15-58 1.65e-11

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 58.30  E-value: 1.65e-11
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 749385045   15 PGAFHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNI 58
Cdd:pfam13855  18 DGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-104 7.58e-11

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 61.87  E-value: 7.58e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  15 PGAFHGLQHLQVLNLTQNSLLSLESRLFhSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMP 94
Cdd:COG4886  152 PEPLGNLTNLKSLDLSNNQLTDLPEELG-NLTNLKELDLSNNQITDLPEPLGN-LTNLEELDLSGNQLTDLPEP-LANLT 228

                         90
                 ....*....|
gi 749385045  95 SVRLLLLKDN 104
Cdd:COG4886  229 NLETLDLSNN 238
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
17-104 1.53e-10

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 60.72  E-value: 1.53e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  17 AFHGLQHLQVLNLTQNSLLSLESRLfHSLPQLRELDLSSNNISHLPTSLGEtWENLTILAVQQNQLQQLDRAlLESMPSV 96
Cdd:COG4886  108 ELSNLTNLESLDLSGNQLTDLPEEL-ANLTNLKELDLSNNQLTDLPEPLGN-LTNLKSLDLSNNQLTDLPEE-LGNLTNL 184


                 ....*...
gi 749385045  97 RLLLLKDN 104
Cdd:COG4886  185 KELDLSNN 192
LRR COG4886
Leucine-rich repeat (LRR) protein [Transcription];
15-117 8.16e-09

Leucine-rich repeat (LRR) protein [Transcription];


Pssm-ID: 443914 [Multi-domain]  Cd Length: 414  Bit Score: 55.71  E-value: 8.16e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  15 PGAFHGLQHLQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLPTSLGetWENLTILAVQQNQLQQLDRALLESMP 94
Cdd:COG4886  221 PEPLANLTNLETLDLSNNQLTDLPE--LGNLTNLEELDLSNNQLTDLPPLAN--LTNLKTLDLSNNQLTDLKLKELELLL 296

                         90       100
                 ....*....|....*....|...
gi 749385045  95 SVRLLLLKDNLWKCNCHLLGLKL 117
Cdd:COG4886  297 GLNSLLLLLLLLNLLELLILLLL 319
LRR_8 pfam13855
Leucine rich repeat;
46-105 6.21e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.29  E-value: 6.21e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045   46 PQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQLDRALLESMPSVRLLLLKDNL 105
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNR 60
LRR_8 pfam13855
Leucine rich repeat;
22-82 6.73e-08

Leucine rich repeat;


Pssm-ID: 404697 [Multi-domain]  Cd Length: 61  Bit Score: 48.29  E-value: 6.73e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 749385045   22 QHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQL 82
Cdd:pfam13855   1 PNLRSLDLSNNRLTSLDDGAFKGLSNLKVLDLSNNLLTTLSPGAFSGLPSLRYLDLSGNRL 61
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 24-80 5.79e-05

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 43.24  E-value: 5.79e-05
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*....
gi 749385045  24 LQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLP--TSLGETWENLTILAVQQN 80
Cdd:cd21340  122 LRVLNISGNNIDSLEP--LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGN 178
LRR_4 pfam12799
Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a ...
 22-57 3.28e-04

Leucine Rich repeats (2 copies); Leucine rich repeats are short sequence motifs present in a number of proteins with diverse functions and cellular locations. These repeats are usually involved in protein-protein interactions. Each Leucine Rich Repeat is composed of a beta-alpha unit. These units form elongated non-globular structures. Leucine Rich Repeats are often flanked by cysteine rich domains.


Pssm-ID: 463713 [Multi-domain]  Cd Length: 44  Bit Score: 37.61  E-value: 3.28e-04
                          10        20        30
                  ....*....|....*....|....*....|....*.
gi 749385045   22 QHLQVLNLTQNSLLSLEsrLFHSLPQLRELDLSSNN 57
Cdd:pfam12799   1 PNLEVLDLSNNQITDIP--PLAKLPNLETLDLSGNN 34
PLN03150 PLN03150
hypothetical protein; Provisional
 21-82 3.73e-04

hypothetical protein; Provisional


Pssm-ID: 178695 [Multi-domain]  Cd Length: 623  Bit Score: 41.73  E-value: 3.73e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 749385045  21 LQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLGETwENLTILAVQQNQL 82
Cdd:PLN03150 441 LRHLQSINLSGNSIRGNIPPSLGSITSLEVLDLSYNSFNgSIPESLGQL-TSLRILNLNGNSL 502
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 18-62 6.55e-04

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 40.15  E-value: 6.55e-04
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 749385045  18 FHGLQHLQVLNLTQNSLLSLE--SRLFHSLPQLRELDLSSNNISHLP 62
Cdd:cd21340  138 LAPLRNLEQLDASNNQISDLEelLDLLSSWPSLRELDLTGNPVCKKP 184
PPP1R42 cd21340
protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 ...
 18-104 2.56e-03

protein phosphatase 1 regulatory subunit 42; Protein phosphatase 1 regulatory subunit 42 (PPP1R42), also known as leucine-rich repeat-containing protein 67 (lrrc67) or testis leucine-rich repeat (TLRR) protein, plays a role in centrosome separation. PPP1R42 has been shown to interact with the well-conserved signaling protein phosphatase-1 (PP1) and thereby increasing PP1's activity, which counters centrosome separation. Inhibition of PPP1R42 expression increases the number of centrosomes per cell while its depletion reduces the activity of PP1 leading to activation of NEK2, the kinase responsible for phosphorylation of centrosomal linker proteins promoting centrosome separation.


Pssm-ID: 411060 [Multi-domain]  Cd Length: 220  Bit Score: 38.23  E-value: 2.56e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  18 FHGLQHLQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNI---------SHLPTSLGETwenLTILAVQQNQLQQLDra 88
Cdd:cd21340   64 LENLVNLKKLYLGGNRISVVEG--LENLTNLEELHIENQRLppgekltfdPRSLAALSNS---LRVLNISGNNIDSLE-- 136

                         90
                 ....*....|....*.
gi 749385045  89 LLESMPSVRLLLLKDN 104
Cdd:cd21340  137 PLAPLRNLEQLDASNN 152
LRR smart00370
Leucine-rich repeats, outliers;
45-62 2.66e-03

Leucine-rich repeats, outliers;


Pssm-ID: 197688 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.66e-03
                           10
                   ....*....|....*...
gi 749385045    45 LPQLRELDLSSNNISHLP 62
Cdd:smart00370   1 LPNLRELDLSNNQLSSLP 18
LRR_TYP smart00369
Leucine-rich repeats, typical (most populated) subfamily;
45-62 2.66e-03

Leucine-rich repeats, typical (most populated) subfamily;


Pssm-ID: 197687 [Multi-domain]  Cd Length: 24  Bit Score: 34.63  E-value: 2.66e-03
                           10
                   ....*....|....*...
gi 749385045    45 LPQLRELDLSSNNISHLP 62
Cdd:smart00369   1 LPNLRELDLSNNQLSSLP 18
PLN00113 PLN00113
leucine-rich repeat receptor-like protein kinase; Provisional
 18-104 5.61e-03

leucine-rich repeat receptor-like protein kinase; Provisional


Pssm-ID: 215061 [Multi-domain]  Cd Length: 968  Bit Score: 37.91  E-value: 5.61e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045  18 FHGLQHLQVLNLTQNSLLSLESRLFHSLPQLRELDLSSNNIS-HLPTSLgETWENLTILAVQQNQLQQLDRALLESMPSV 96
Cdd:PLN00113 471 SFGSKRLENLDLSRNQFSGAVPRKLGSLSELMQLKLSENKLSgEIPDEL-SSCKKLVSLDLSHNQLSGQIPASFSEMPVL 549


                 ....*...
gi 749385045  97 RLLLLKDN 104
Cdd:PLN00113 550 SQLDLSQN 557
LRR_9 pfam14580
Leucine-rich repeat;
21-104 5.94e-03

Leucine-rich repeat;


Pssm-ID: 405295 [Multi-domain]  Cd Length: 175  Bit Score: 36.67  E-value: 5.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 749385045   21 LQHLQVLNLTQNSLLSLESrlFHSLPQLRELDLSSNNISHLPTSLGETWENLTILAVQQNQLQQL-DRALLESMPSVRLL 99
Cdd:pfam14580  41 LDQFDTIDFSDNEIRKLDG--FPLLRRLKTLLLNNNRICRIGEGLGEALPNLTELILTNNNLQELgDLDPLASLKKLTFL 118


                  ....*
gi 749385045  100 LLKDN 104
Cdd:pfam14580 119 SLLRN 123
LRRCT smart00082
Leucine rich repeat C-terminal domain;
104-157 7.25e-03

Leucine rich repeat C-terminal domain;


Pssm-ID: 214507 [Multi-domain]  Cd Length: 51  Bit Score: 33.94  E-value: 7.25e-03
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....
gi 749385045   104 NLWKCNCHLLGLKLWLEKFVYKGGlTDGIICESPDTWKGKdLLRIPHELyQPCP 157
Cdd:smart00082   1 NPFICDCELRWLLRWLQANEHLQD-PVDLRCASPSSLRGP-LLELLHSE-FKCP 51
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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