RecName: Full=BRI3-binding protein; Short=I3-binding protein; AltName: Full=Cervical cancer 1 proto-oncogene-binding protein KG19; AltName: Full=HCCRBP-1
BRI3BP domain-containing protein( domain architecture ID 10633157)
BRI3BP domain-containing protein
List of domain hits
Name | Accession | Description | Interval | E-value | ||||
BRI3BP | pfam14965 | Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. ... |
49-239 | 3.68e-55 | ||||
Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. Proteins in this family are typically between 213 and 245 amino acids in length. It is found in various tissues, including the brain, liver and kidneys. It was first discovered as a functional unknown gene, murine brain I3 (BRI3). This protein is also known as HCCRBP-1 and it plays a role in tumourigenesis, as it binds to an oncogene, HCCR-1, and acts as a negative regulator of p53/TP53 tumour suppressor. BRI3BP induces tumourigenesis by activating protein kinase C (PKC) activity but decreasing the pro-apoptotic PKC-alpha and PKC-delta isoform levels. BRI3BP is over-expressed in many tumours. : Pssm-ID: 464410 Cd Length: 180 Bit Score: 175.20 E-value: 3.68e-55
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Name | Accession | Description | Interval | E-value | ||||
BRI3BP | pfam14965 | Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. ... |
49-239 | 3.68e-55 | ||||
Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. Proteins in this family are typically between 213 and 245 amino acids in length. It is found in various tissues, including the brain, liver and kidneys. It was first discovered as a functional unknown gene, murine brain I3 (BRI3). This protein is also known as HCCRBP-1 and it plays a role in tumourigenesis, as it binds to an oncogene, HCCR-1, and acts as a negative regulator of p53/TP53 tumour suppressor. BRI3BP induces tumourigenesis by activating protein kinase C (PKC) activity but decreasing the pro-apoptotic PKC-alpha and PKC-delta isoform levels. BRI3BP is over-expressed in many tumours. Pssm-ID: 464410 Cd Length: 180 Bit Score: 175.20 E-value: 3.68e-55
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Name | Accession | Description | Interval | E-value | ||||
BRI3BP | pfam14965 | Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. ... |
49-239 | 3.68e-55 | ||||
Negative regulator of p53/TP53; This family of transmembrane proteins is found in eukaryotes. Proteins in this family are typically between 213 and 245 amino acids in length. It is found in various tissues, including the brain, liver and kidneys. It was first discovered as a functional unknown gene, murine brain I3 (BRI3). This protein is also known as HCCRBP-1 and it plays a role in tumourigenesis, as it binds to an oncogene, HCCR-1, and acts as a negative regulator of p53/TP53 tumour suppressor. BRI3BP induces tumourigenesis by activating protein kinase C (PKC) activity but decreasing the pro-apoptotic PKC-alpha and PKC-delta isoform levels. BRI3BP is over-expressed in many tumours. Pssm-ID: 464410 Cd Length: 180 Bit Score: 175.20 E-value: 3.68e-55
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Blast search parameters | ||||
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