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Conserved domains on  [gi|74719211|sp|Q9NSQ0|]
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PUTATIVE PSEUDOGENE: RecName: Full=Putative ribosomal RNA-processing protein 7 homolog B; AltName: Full=Putative gastric cancer antigen Zg14-like protein

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RRP7_like super family cl15166
RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p), ribosomal RNA-processing protein 7 ...
 1-103 3.60e-35

RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p), ribosomal RNA-processing protein 7 homolog A (Rrp7A), and similar proteins; This CD corresponds to the RRP7 domain of Rrp7p and Rrp7A. Rrp7p is encoded by YCL031C gene from Saccharomyces cerevisiae. It is an essential yeast protein involved in pre-rRNA processing and ribosome assembly, and is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle. Rrp7A, also termed gastric cancer antigen Zg14, is the Rrp7p homolog mainly found in Metazoans. The cellular function of Rrp7A remains unclear currently. Both Rrp7p and Rrp7A harbor an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal RRP7 domain.


The actual alignment was detected with superfamily member cd12951:

Pssm-ID: 449475 [Multi-domain]  Cd Length: 129  Bit Score: 116.61  E-value: 3.60e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211   1 MEAYDQKIAEEEAKAKEEeGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:cd12951  27 MEEYDKEEEEEKEEKEKE-AEPDEDGWVTVTKKGRRPKTARKESVAAKAAEKEKKKKKKKELKNfYRFQIRESKRNELAE 105

                        90       100
                ....*....|....*....|....
gi 74719211  80 LRKKFEEDKQRIELLRAQRKFRPY 103
Cdd:cd12951 106 LRKKFEEDKKRIALLKAARKFKPY 129
 
Name Accession Description Interval E-value
RRP7_Rrp7A cd12951
RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins; The ...
 1-103 3.60e-35

RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins; The family corresponds to the RRP7 domain of Rrp7A, also termed gastric cancer antigen Zg14, and similar proteins which are yeast ribosomal RNA-processing protein 7 (Rrp7p) homologs mainly found in Metazoans. The cellular function of Rrp7A remains unclear currently. Rrp7A harbors an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal RRP7 domain.


Pssm-ID: 240578 [Multi-domain]  Cd Length: 129  Bit Score: 116.61  E-value: 3.60e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211   1 MEAYDQKIAEEEAKAKEEeGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:cd12951  27 MEEYDKEEEEEKEEKEKE-AEPDEDGWVTVTKKGRRPKTARKESVAAKAAEKEKKKKKKKELKNfYRFQIRESKRNELAE 105

                        90       100
                ....*....|....*....|....
gi 74719211  80 LRKKFEEDKQRIELLRAQRKFRPY 103
Cdd:cd12951 106 LRKKFEEDKKRIALLKAARKFKPY 129
RRP7 pfam12923
Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain; RRP7 is an essential protein in ...
 1-103 6.39e-25

Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain; RRP7 is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle.


Pssm-ID: 432877  Cd Length: 119  Bit Score: 90.44  E-value: 6.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211     1 MEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGrrPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:pfam12923  18 MEEFDAEEEEEKRERKKARNEPDEDGFVTVTRGG--PGGARKEAAEEKIAKKEKKKKKKKELLDfYRFQIREKKKNELAE 95

                          90       100
                  ....*....|....*....|....
gi 74719211    80 LRKKFEEDKQRIELLRAQRKFRPY 103
Cdd:pfam12923  96 LRKKFEEDKEKIEKLKESRKFKPY 119
 
Name Accession Description Interval E-value
RRP7_Rrp7A cd12951
RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins; The ...
 1-103 3.60e-35

RRP7 domain ribosomal RNA-processing protein 7 homolog A (Rrp7A) and similar proteins; The family corresponds to the RRP7 domain of Rrp7A, also termed gastric cancer antigen Zg14, and similar proteins which are yeast ribosomal RNA-processing protein 7 (Rrp7p) homologs mainly found in Metazoans. The cellular function of Rrp7A remains unclear currently. Rrp7A harbors an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal RRP7 domain.


Pssm-ID: 240578 [Multi-domain]  Cd Length: 129  Bit Score: 116.61  E-value: 3.60e-35
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211   1 MEAYDQKIAEEEAKAKEEeGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:cd12951  27 MEEYDKEEEEEKEEKEKE-AEPDEDGWVTVTKKGRRPKTARKESVAAKAAEKEKKKKKKKELKNfYRFQIRESKRNELAE 105

                        90       100
                ....*....|....*....|....
gi 74719211  80 LRKKFEEDKQRIELLRAQRKFRPY 103
Cdd:cd12951 106 LRKKFEEDKKRIALLKAARKFKPY 129
RRP7_like cd12932
RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p), ribosomal RNA-processing protein 7 ...
 1-91 1.03e-25

RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p), ribosomal RNA-processing protein 7 homolog A (Rrp7A), and similar proteins; This CD corresponds to the RRP7 domain of Rrp7p and Rrp7A. Rrp7p is encoded by YCL031C gene from Saccharomyces cerevisiae. It is an essential yeast protein involved in pre-rRNA processing and ribosome assembly, and is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle. Rrp7A, also termed gastric cancer antigen Zg14, is the Rrp7p homolog mainly found in Metazoans. The cellular function of Rrp7A remains unclear currently. Both Rrp7p and Rrp7A harbor an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal RRP7 domain.


Pssm-ID: 240576 [Multi-domain]  Cd Length: 118  Bit Score: 92.32  E-value: 1.03e-25
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211   1 MEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:cd12932  27 MEEFDKREEEEKEEAKEARNEPDEDGFVTVTRGGRKGKTAREEAVEAKAKEKEKKKKKKKELEDfYRFQIREKKKEELAE 106

                        90
                ....*....|..
gi 74719211  80 LRKKFEEDKQRI 91
Cdd:cd12932 107 LRKKFEEDKKRI 118
RRP7 pfam12923
Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain; RRP7 is an essential protein in ...
 1-103 6.39e-25

Ribosomal RNA-processing protein 7 (RRP7) C-terminal domain; RRP7 is an essential protein in yeast that is involved in pre-rRNA processing and ribosome assembly. It is speculated to be required for correct assembly of rpS27 into the pre-ribosomal particle.


Pssm-ID: 432877  Cd Length: 119  Bit Score: 90.44  E-value: 6.39e-25
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211     1 MEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGrrPVLPRTEAASLRVLERERRKRSQKELLN-YAWQHRESKMEHLAQ 79
Cdd:pfam12923  18 MEEFDAEEEEEKRERKKARNEPDEDGFVTVTRGG--PGGARKEAAEEKIAKKEKKKKKKKELLDfYRFQIREKKKNELAE 95

                          90       100
                  ....*....|....*....|....
gi 74719211    80 LRKKFEEDKQRIELLRAQRKFRPY 103
Cdd:pfam12923  96 LRKKFEEDKEKIEKLKESRKFKPY 119
RRP7_Rrp7p cd12950
RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p) and similar proteins; This CD ...
 1-98 8.51e-11

RRP7 domain ribosomal RNA-processing protein 7 (Rrp7p) and similar proteins; This CD corresponds to the RRP7 domain of Rrp7p. Rrp7p is encoded by YCL031C gene from Saccharomyces cerevisiae. It is an essential yeast protein involved in pre-rRNA processing and ribosome assembly. Rrp7p contains an N-terminal RNA recognition motif (RRM), also termed RBD (RNA binding domain) or RNP (ribonucleoprotein domain), and a C-terminal RRP7 domain.


Pssm-ID: 240577  Cd Length: 128  Bit Score: 54.59  E-value: 8.51e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74719211   1 MEAYDQKIAEEEAKAKEEEGVPDEEGWVKVTRRGRRPVLPRTEAASLRVLER---ERRKRSQKELLN-YAWQHRESKMEH 76
Cdd:cd12950  27 MALFEAREEERKRERKRLRNEPDEDGFVTVVRGGRKGPAAGEEAGKAAEEEKkekEKKKKKKKELEDfYRFQLREKKKEE 106

                        90       100
                ....*....|....*....|..
gi 74719211  77 LAQLRKKFEEDKQRIELLRAQR 98
Cdd:cd12950 107 QADLLKKFEEDKERVEKMKEKR 128
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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