NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|746198624|ref|WP_039256421|]
View 

FeoA domain-containing protein [Clostridium botulinum]

Protein Classification

ferrous iron transport protein A( domain architecture ID 10004922)

ferrous iron transport protein A (FeoA) is part of the Feo (ferrous iron-transport) system that functions in the uptake of ferrous iron

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
4-74 2.73e-18

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


:

Pssm-ID: 441522  Cd Length: 73  Bit Score: 71.32  E-value: 2.73e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624  4 LPLNFFVEGESGVVEDIKGDTNLFQRLSSMGFNKGATLQVVKNDL--GPLIVALGGNRVAVERAIAHKIMLEP 74
Cdd:COG1918   1 MTLSELKPGEKARIVRISGDGELRRRLLELGLVPGTEVEVVRKAPlgGPLVVRVGGTRIALRREEAAKILVEP 73
 
Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
4-74 2.73e-18

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


Pssm-ID: 441522  Cd Length: 73  Bit Score: 71.32  E-value: 2.73e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624  4 LPLNFFVEGESGVVEDIKGDTNLFQRLSSMGFNKGATLQVVKNDL--GPLIVALGGNRVAVERAIAHKIMLEP 74
Cdd:COG1918   1 MTLSELKPGEKARIVRISGDGELRRRLLELGLVPGTEVEVVRKAPlgGPLVVRVGGTRIALRREEAAKILVEP 73
FeoA pfam04023
FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. ...
 5-74 8.57e-15

FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.


Pssm-ID: 461133  Cd Length: 74  Bit Score: 62.22  E-value: 8.57e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624   5 PLNFFVEGESGVVEDI-KGDTNLFQRLSSMGFNKGATLQVVKNDL--GPLIVALGGNRVAVERAIAHKIMLEP 74
Cdd:pfam04023  2 PLSELKEGETARIVRIrDGDPELLRRLLELGLVPGAEVTVVRKAPfgGPIIVRVGGTRIALRREEASKIFVEP 74
FeoA smart00899
This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found ...
 4-74 8.65e-14

This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment.


Pssm-ID: 214896  Cd Length: 72  Bit Score: 59.89  E-value: 8.65e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624    4 LPLNFFVEGESGVVEDIKG-DTNLFQRLSSMGFNKGATLQVVKND-LGPLIVALGGnRVAVERAIAHKIMLEP 74
Cdd:smart00899  1 MPLSELKPGEKARIVRIRDeDPELLRRLLELGLVPGTEVTVLRKApFGPLVVRVGG-ELALRREEAEKIFVEP 72
 
Name Accession Description Interval E-value
FeoA COG1918
Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];
4-74 2.73e-18

Fe2+ transport protein FeoA [Inorganic ion transport and metabolism];


Pssm-ID: 441522  Cd Length: 73  Bit Score: 71.32  E-value: 2.73e-18
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624  4 LPLNFFVEGESGVVEDIKGDTNLFQRLSSMGFNKGATLQVVKNDL--GPLIVALGGNRVAVERAIAHKIMLEP 74
Cdd:COG1918   1 MTLSELKPGEKARIVRISGDGELRRRLLELGLVPGTEVEVVRKAPlgGPLVVRVGGTRIALRREEAAKILVEP 73
FeoA pfam04023
FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. ...
 5-74 8.57e-15

FeoA domain; This family includes FeoA a small protein, probably involved in Fe2+ transport. This presumed short domain is also found at the C-terminus of a variety of metal dependent transcriptional regulators. This suggests that this domain may be metal-binding. In most cases this is likely to be either iron or manganese.


Pssm-ID: 461133  Cd Length: 74  Bit Score: 62.22  E-value: 8.57e-15
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624   5 PLNFFVEGESGVVEDI-KGDTNLFQRLSSMGFNKGATLQVVKNDL--GPLIVALGGNRVAVERAIAHKIMLEP 74
Cdd:pfam04023  2 PLSELKEGETARIVRIrDGDPELLRRLLELGLVPGAEVTVVRKAPfgGPIIVRVGGTRIALRREEASKIFVEP 74
FeoA smart00899
This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found ...
 4-74 8.65e-14

This entry represents the core domain of the ferrous iron (Fe2+) transport protein FeoA found in bacteria; This domain also occurs at the C-terminus in related proteins. The transporter Feo is composed of three proteins: FeoA a small, soluble SH3-domain protein probably located in the cytosol; FeoB, a large protein with a cytosolic N-terminal G-protein domain and a C-terminal integral inner-membrane domain containing two 'Gate' motifs which likely functions as the Fe2+ permease; and FeoC, a small protein apparently functioning as an [Fe-S]-dependent transcriptional repressor. Feo allows the bacterial cell to acquire iron from its environment.


Pssm-ID: 214896  Cd Length: 72  Bit Score: 59.89  E-value: 8.65e-14
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 746198624    4 LPLNFFVEGESGVVEDIKG-DTNLFQRLSSMGFNKGATLQVVKND-LGPLIVALGGnRVAVERAIAHKIMLEP 74
Cdd:smart00899  1 MPLSELKPGEKARIVRIRDeDPELLRRLLELGLVPGTEVTVLRKApFGPLVVRVGG-ELALRREEAEKIFVEP 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH