NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|745999946|ref|YP_009114745|]
View 

NADH dehydrogenase subunit 2 (mitochondrion) [Indri indri]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 4.37e-157

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.90  E-value: 4.37e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999946 321 KHTLFLPPLIILST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 4.37e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.90  E-value: 4.37e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999946 321 KHTLFLPPLIILST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 7.86e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.53  E-value: 7.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   23 SSHWLLAWMGLEINMLAIIP-ILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHN---------- 91
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKaltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   92 -SLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLL-TWQKLAPISIM-----LQIYSSMNLNVLLPFALLSILV 164
Cdd:pfam00361  81 lLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILM----YCPSLTILNLLIYLMLTITMFTMLNINT-----NTTTLTLSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 745999946  236 KNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 3.18e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.25  E-value: 3.18e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   7 PVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIpILV--KKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQW 84
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  85 NITNMHNSLISFT------------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLN 152
Cdd:COG1007  184 NLAGIAAALAAGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 153 -------VLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM------------AILMYcpsltilnLLIYLMLTI 213
Cdd:COG1007  264 laadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlglaagtplgvsAALFY--------LLAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 214 TMFTMLNINTNTTTLTLSN-----LWNKNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALL 288
Cdd:COG1007  336 GAFAVILLLSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 745999946 289 NLYFYMRLIY 298
Cdd:COG1007  416 SAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-297 1.94e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.07  E-value: 1.94e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946    6 LPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAI-IPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   85 NITNMHNSLISFT------------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIY------ 146
Cdd:TIGR01770 184 NFEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  147 -SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMfTMLNINTNT 225
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLS 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  226 TTLTLSNLWNK-----------NPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYM 294
Cdd:TIGR01770 343 LLRSYKDEWIEyisdfaglfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422


                  ...
gi 745999946  295 RLI 297
Cdd:TIGR01770 423 RVV 425
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 4.37e-157

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 443.90  E-value: 4.37e-157
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999946 321 KHTLFLPPLIILST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-334 2.70e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 337.93  E-value: 2.70e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIySSMNLNVLLPFALL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQI-APTNPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330
                 ....*....|....
gi 745999946 321 KHTLFLPPLIILST 334
Cdd:MTH00135 320 QLTLPLAISTTATL 333
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-334 1.44e-111

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 328.32  E-value: 1.44e-111
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330
                 ....*....|....
gi 745999946 321 KHTLfLPPLIILST 334
Cdd:MTH00112 321 KNTL-TATLTTLST 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-334 7.13e-109

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 321.49  E-value: 7.13e-109
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFqPT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330
                 ....*....|....
gi 745999946 321 KHTLFLPPLIILST 334
Cdd:MTH00070 320 KTNNLLSLTIILSL 333
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-334 1.96e-77

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 241.41  E-value: 1.96e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320

                        330
                 ....*....|....
gi 745999946 321 KHtLFLPPLIILST 334
Cdd:MTH00200 321 SN-LLVGLLLLLSI 333
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-307 3.68e-75

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 235.60  E-value: 3.68e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TGQWNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPT 307
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 13-315 3.41e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 159.67  E-value: 3.41e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  13 ILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMhns 92
Cdd:MTH00144  13 MVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSMSL--- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  93 lisftIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNL-NVLLPFALLSILVGGWGGLN 171
Cdd:MTH00144  90 -----LLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIGGLN 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 172 QTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLwNKNPMITLAILISLLSL 251
Cdd:MTH00144 165 QTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLLLSL 243

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 745999946 252 GGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKW 315
Cdd:MTH00144 244 GGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-333 7.89e-46

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 159.22  E-value: 7.89e-46
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   1 MNPITLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMN 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  81 TgqwnitNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIyssMNLNVLLPFALL 160
Cdd:MTH00160  82 L------MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMI 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 241 TLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQFQPT 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                        330
                 ....*....|...
gi 745999946 321 KHTLFLPPLIILS 333
Cdd:MTH00160 313 LILNFLSFISLFG 325
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 5-300 2.13e-41

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 147.23  E-value: 2.13e-41
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   5 TLPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISamntgqW 84
Cdd:MTH00011   7 TMFLFSSTMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMM------W 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  85 NITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALLSILV 164
Cdd:MTH00011  81 SFPSLLKNITALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMITLAI 244
Cdd:MTH00011 161 GGLGGMNQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSL 240

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 745999946 245 LISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSS 300
Cdd:MTH00011 241 FIMLLSLGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFNF 296
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-332 9.42e-36

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 132.10  E-value: 9.42e-36
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  12 SILTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNtgqwnitNMHN 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFSN-------LYLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  92 SLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLnvLLPFALLSILVGGWGGLN 171
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFMG--LLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 172 QTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNLWNKNPMITLAILISLLSL 251
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 252 GGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSS-SLTMFPTSNNMKMKWQFQPTKHTLFLPPLI 330
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSlILSNWMINFLMKINLLYSGLFILLMMMLPL 316


                 ..
gi 745999946 331 IL 332
Cdd:MTH00197 317 LM 318
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 7-215 3.10e-22

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 97.01  E-value: 3.10e-22
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   7 PVIMTSILTGTILTMVSSHWLLAWMGLEINMLAI-IPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWN 85
Cdd:MTH00199 100 PILILIVALGSLLLVSSINWLSIYLAIELQTLTLfILVALKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  86 ITNMHNSLISFT----IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIysSMNLNVLLPFALLS 161
Cdd:MTH00199 180 IQGINSILTGDVgkilITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQI--GPVTNVVLICAVLS 257

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....
gi 745999946 162 ILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITM 215
Cdd:MTH00199 258 IIYGAIGALNQTKIKRLLAYSGIGHMGFILFGVAIGSFESIQASLIYMIIYVIM 311
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-281 7.86e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 93.53  E-value: 7.86e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   23 SSHWLLAWMGLEINMLAIIP-ILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHN---------- 91
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLlIGYWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKaltgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   92 -SLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLL-TWQKLAPISIM-----LQIYSSMNLNVLLPFALLSILV 164
Cdd:pfam00361  81 lLLLFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIrrsllYLPSSPFIQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  165 GGWGGLNQTQLRKILAYSSIAHMGWMMAILM----YCPSLTILNLLIYLMLTITMFTMLNINT-----NTTTLTLSNLWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALGagtiYGIQAAIFHLLTHGLFSAGLFLCAGSVIyrrvhTRNIRDYGGLAK 240

                         250       260       270       280
                  ....*....|....*....|....*....|....*....|....*.
gi 745999946  236 KNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATI 281
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLA 286
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 13-297 6.09e-21

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 92.40  E-value: 6.09e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  13 ILTGTILTMVSSHWLLAWMGLEINMLAI-IPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNIT---- 87
Cdd:MTH00196   2 VALGILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCALLCGTTGGLHLSyinl 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  88 --NMHNSLISFT-------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIysSMNLNVLLPFA 158
Cdd:MTH00196  82 vlNSGQSFSSVSvpigyllIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSI--GLNVNILLIGG 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 159 LLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSNL----- 233
Cdd:MTH00196 160 LFSLFVGAIGALNQTKIKRLLAYSGIGHMGFVLWGIEIGSFESIQASLVYLFIYIIMSICVFSIILALNVYKNLIiefsg 239

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 745999946 234 -WNKNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLI 297
Cdd:MTH00196 240 lSRRLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 7-298 3.18e-19

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 88.25  E-value: 3.18e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   7 PVIMTSILTGTILTMVSSHWLLAWMGLEINMLAIIpILV--KKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQW 84
Cdd:COG1007  105 YALLLFATLGMMLMASANDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSL 183

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  85 NITNMHNSLISFT------------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLN 152
Cdd:COG1007  184 NLAGIAAALAAGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAALLRLLVEAFPG 263

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 153 -------VLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM------------AILMYcpsltilnLLIYLMLTI 213
Cdd:COG1007  264 laadwqlLLAVLAVLSMTVGNLAALAQTNVKRMLAYSSIAHAGYLLlglaagtplgvsAALFY--------LLAYLFMNL 335

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 214 TMFTMLNINTNTTTLTLSN-----LWNKNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALL 288
Cdd:COG1007  336 GAFAVILLLSRKGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVI 415

                        330
                 ....*....|
gi 745999946 289 NLYFYMRLIY 298
Cdd:COG1007  416 SAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 6-297 1.94e-17

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 83.07  E-value: 1.94e-17
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946    6 LPVIMTSILTGTILTMVSSHWLLAWMGLEINMLAI-IPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQW 84
Cdd:TIGR01770 104 FYILLLFALLGIFLLVSSNDLLSIYLGLELQSLCFyVLAGLKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSL 183

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   85 NITNMHNSLISFT------------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIY------ 146
Cdd:TIGR01770 184 NFEDLLLFLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFlyilfg 263

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  147 -SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMfTMLNINTNT 225
Cdd:TIGR01770 264 fSEAWQIFLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIYALM-SLGAFGVLS 342

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  226 TTLTLSNLWNK-----------NPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYM 294
Cdd:TIGR01770 343 LLRSYKDEWIEyisdfaglfktNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYL 422


                  ...
gi 745999946  295 RLI 297
Cdd:TIGR01770 423 RVV 425
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
7-209 4.68e-16

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 78.71  E-value: 4.68e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   7 PVIMTSILtGTILTMVSSHWLLAWMGLEINMLAI-IPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWN 85
Cdd:PRK05777 107 LLVLFALL-GMMVMVSANDLLTLFLGLELLSLPLyALAALRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLS 185

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  86 ITNMHNSLISFT------------IIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQI-------Y 146
Cdd:PRK05777 186 FAGIAKALADGSgnsllllfglvfLLVGLAFKLSAVPFHMWTPDVYEGAPTPVTAFLATAPKIAAFAVLLRLlvvafggL 265

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 745999946 147 SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYL 209
Cdd:PRK05777 266 SEDWQQVLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLLVGLAAGTAEGYSAVLFYL 328
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 14-301 1.98e-13

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 70.56  E-value: 1.98e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  14 LTGTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHN-- 91
Cdd:COG0651  117 LAGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAArl 196

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  92 --------SLISFTIIIALMMKLGMAPFHFWVPE-----------VTQGVTLIVGM--LLLTWQKLAPISIMLQIyssmn 150
Cdd:COG0651  197 aeldpgllLAAFALLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVyaILRVLTLLFGADPALFL----- 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 151 LNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYL----MLTITMF----TMLNIN 222
Cdd:COG0651  272 GTLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhaLAKALLFlaagAIERAT 351

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999946 223 TNTTTLTLSNLWNKNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSS 301
Cdd:COG0651  352 GTRDLDKLGGLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-191 1.74e-12

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 68.35  E-value: 1.74e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  16 GTILTMVSSHWLLAWMGLEINMLAIIPILVKKINPRST---------EAATKYFLTQATASMLLMM-------------- 72
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFgcalyfgftgnegm 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  73 --TIVISAMNTGqwNITNMHNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMN 150
Cdd:MTH00198 280 lgTILSATLETT--NIELRQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLVITSK 357

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|.
gi 745999946 151 LnvLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM 191
Cdd:MTH00198 358 L--LLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFIL 396
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-334 3.23e-10

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 54.96  E-value: 3.23e-10
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 745999946  291 YFYMRLIYSSSLTMFPTSNNMKMKWQFQPTKHTLFLPPLIILST 334
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSI 44
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 1.32e-09

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 59.32  E-value: 1.32e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  55 AATKYFLTQATASMLLMMTIVISAMNTGQW--NITNMHNSLISFT--------IIIALMMKLGMAPFHFWVPEV-----T 119
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALtfDIAELAAAPLPLTaqlllflaFFIAFAVKVPMFPFHTWLPDAhveapT 241

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999946 120 QGVTLIVGMLLltwqKLAP---ISIMLQIY---SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMA 192
Cdd:COG1008  242 AGSVLLAGVLL----KMGGyglLRFALPLFpeaSAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 1.21e-08

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 56.04  E-value: 1.21e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  33 LEINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHNSL--------ISFTIIIALMM 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALaenptvvtAFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 105 KLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSM----------NLNVLLPFALLSILVGGWGGLNQTQ 174
Cdd:PRK08375 215 KAAVFPLHTWLPRAYPAAPPVVTALLSGLVTKVAVYALIRIYFTVfggdfrfalgLGWLLAVLALLSMLVGSLAALGQDD 294

                        170
                 ....*....|....*..
gi 745999946 175 LRKILAYSSIAHMGWMM 191
Cdd:PRK08375 295 VKRVLAYSTVSQMGYIL 311
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-191 8.43e-08

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 53.40  E-value: 8.43e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946   55 AATKYFLTQATASMLLMMTIVISAMNTGQ-WNITNMHNSLISFT--------IIIALMMKLGMAPFHFWVPEV-----TQ 120
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGGtFDLLELLNLPLPFGvqtwlflaFFIAFAVKVPLFPLHTWLPDAhveapTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999946  121 GVTLIVGMLLltwqKLAPISIM---LQIY---SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM 191
Cdd:TIGR01972 237 GSVILAGVLL----KMGTYGFLrfnLPLFpdaSLYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 49-194 5.06e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 51.31  E-value: 5.06e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  49 NPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHNS-----------LISFTIIIALMMKLGMAPFHFWVPE 117
Cdd:COG1009  157 KPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELLAAaptilssplltLILLLLLLGAFGKSAQFPLHFWLPD 236

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 118 -----------------VTQGVTLIVgmllltwqKLAPISIMlqiySSMNLNVLLPFALLSILVGGWGGLNQTQLRKILA 180
Cdd:COG1009  237 amegptpvsallhaatmVKAGVYLLA--------RLSPLFAL----SPVWLTVVAIIGAITALFAALIALAQTDIKRVLA 304

                        170
                 ....*....|....
gi 745999946 181 YSSIAHMGWMMAIL 194
Cdd:COG1009  305 YSTVSQLGYMFLAL 318
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 5.54e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 50.97  E-value: 5.54e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  55 AATKYFLTQATASMLLMMTI----VISAMNTGQWNITNMHNSLISFTIIIALMM--------KLGMAPFHFWVPEV---- 118
Cdd:PRK05846 162 AATKFFLYTLLGSLLMLVAIiylvVVYYNATGTFDIADLLNLPLPPGVQYWLFLaffiafavKMPMFPLHTWLPDAhvqa 241

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 119 -TQGVTLIVGMLLltwqKLAP---ISIMLQIY---SSMNLNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM 191
Cdd:PRK05846 242 pTAGSVLLAGILL----KMGAyglLRFSLPLFpdaSHEFAPIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGFVT 317
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
47-297 7.07e-07

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 50.82  E-value: 7.07e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  47 KINPRSTEAATKYFLTQATAS-MLLMMTIVISAMNTGQWNITNMHNSLI---SFTIIIALMM-------KLGMAPFHFWV 115
Cdd:PRK02504 154 KRDPRSNEAALKYLLIGAASSaIFLYGSSLLYGLSGGSTQLSAIALALItspSLGLALALVFviagiafKISAVPFHQWT 233

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 116 PEVTQGVTLIVGMLLLTWQKLA----PISIMLQIYSSMNLNVLLPF---ALLSILVGGWGGLNQTQLRKILAYSSIAHMG 188
Cdd:PRK02504 234 PDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFDEQWKLLFtalAILSMVLGNVVALAQTSMKRMLAYSSIGQAG 313

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 189 WMMaILMYCP-----SLTILNLLIYLMLTITMFTMLNINTNTT----TLTLSNLWNKNPMITLAILISLLSLGGLPPLTG 259
Cdd:PRK02504 314 FVM-IGLVAGteagyASMVFYLLAYLFMNLGAFACVILFSLRTgtdqISDYAGLYQKDPLLTLGLSLCLLSLGGIPPLAG 392

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 745999946 260 FLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLI 297
Cdd:PRK02504 393 FFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVI 430
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 96-317 3.28e-06

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 47.94  E-value: 3.28e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  96 FTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLPFALLSILVggwgGLNQTQL 175
Cdd:MTH00091  61 YFQFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSY 136

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 176 RKILAYSSIAHMGWMMAILMYCPSLTILNLLIYLMLTITMFtmlnintntttltlsNLWNKNPMITLAILISLLSLGGLP 255
Cdd:MTH00091 137 KNLLILSSTESFNWLILSFFFSFFNVFFLFFYYFLLMLFLI---------------PKFNNVNKLNFVSWETLLVFMNLP 201

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 745999946 256 PLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYSSSLTMFPTSNNMKMKWQF 317
Cdd:MTH00091 202 FSVTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFFFF 263
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-191 2.03e-05

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 46.18  E-value: 2.03e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  55 AATKYFLTQATASMLLMMTIVISAMNTGQ--WNITNMHNSLISFTI--------IIALMMKLGMAPFHFWVP----EVTQ 120
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAKSYPLALelllyagfLIAFGVKLPIFPLHTWLPdahgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 745999946 121 GVTLIVGMLLLTWQKLAPISIMLQIYSSMNLN---VLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM 191
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALIRFNVQMLPDAHVYfapALAILGVVNIIYGALNAFAQDNVKRRLAYSSVSHMGFVL 291
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-191 3.75e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 45.47  E-value: 3.75e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  33 LEINMLAIIPILVKKIN-PRSTEAATKYFLTQATASMLLMMTIvisAMNTGQWNITNM----HNSLISFTI--------- 98
Cdd:PRK08376 150 LEIMSIASYALVAFRNDtWEAIEAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMaylaVKMSENPTVvakialalf 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  99 IIALMMKLGMAPFHFWVPEV-TQGVTLIVGMLLLTWQK--LAPISIMLQIYS-SMNLN----VLLPFALLSILVGGWGGL 170
Cdd:PRK08376 227 IAGLAMKSGAVPVHMWLPDAyPAAPSSISAMLLVIKQAglYALARVLFSIYGpAINLAtvgwVIIILGCLTMFVGVAMAV 306

                        170       180
                 ....*....|....*....|.
gi 745999946 171 NQTQLRKILAYSSIAHMGWMM 191
Cdd:PRK08376 307 VQKDVKRLLAYHSVSQIGYML 327
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 13-191 5.06e-05

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 44.75  E-value: 5.06e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  13 ILTGTILTMVSSHWLLAWMGLEINMLaIIPILVKKINPRST-EAATKYFLTQATA------SMLLMMTIVISAMNTGQWN 85
Cdd:PRK08676 111 LLSVITFAFFSDNLALFWIFAELTTV-FSAMLIAILSARENiDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLN 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  86 ITNM--HNSLIS--------FTIIIALMMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMN----- 150
Cdd:PRK08676 190 WTELaaHASLLSpsvlgasfLFIFIGFLAKSGLVPFHTWLPAAYAKAPSVVSALLSGTVLNIGIYGILRLSALLRqsgaa 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....
gi 745999946 151 ---LNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMM 191
Cdd:PRK08676 270 eqfSNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLML 313
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 50-299 3.21e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 42.27  E-value: 3.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  50 PRSTEAATKYFLTQATASMLLMMTIVI-------------SAMNTGQWNITNMH---NSLISFTIIIAL-----MMKLGM 108
Cdd:PRK12667 160 GDAVEAAIKYALIGAVGTTLYFLALAFlyatfgtlnmadlSAKIRGLSFPLTGGlagNPPLALGVALALalwafTIKAAI 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 109 APFHFWVPE-----------------VTQGVTLIVGMLLLTWQklapISIMLQIYSSMNLNVLLPFALLSILVGGWGGLN 171
Cdd:PRK12667 240 FPNHFWLPDahpaapspvsamlsglvVNVGAYAIIRFLYTIFG----ISPSLIDFRAALSPILIILGAVSAIIGALMMVV 315

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 172 QTQLRKILAYSSIAHMGWMMAILMYCPSLTILNLLIYL--------MLTITMFTMLNINTNTTTLTLSNLWNKNPMITLA 243
Cdd:PRK12667 316 QKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGLGRKMPIASFA 395

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 745999946 244 ILISLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYS 299
Cdd:PRK12667 396 FLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
ND5 MTH00207
NADH dehydrogenase subunit 5; Provisional
 49-286 1.20e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 164753 [Multi-domain]  Cd Length: 572  Bit Score: 40.52  E-value: 1.20e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  49 NPRSTEAATKYFLTQATASMLLMMTIVISaMNTGQWNITNM----HNSLISFTIIIALMMKLGMAPFHFWVPEVTQGVTL 124
Cdd:MTH00207 133 NPKSLGAGMITALTNRIGDVMLLLSIGWT-LNQGHWSITNMwqtdMNNYIALSIMIAAMTKSAQMPFSSWLPAAMAAPTP 211

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 125 IVGMLLLTWQKLAPISIMLQIYSSMN-----LNVLLPFALLSILVGGWGGLNQTQLRKILAYSSIAHMGWMMAIL-MYCP 198
Cdd:MTH00207 212 VSALVHSSTLVTAGVFLLIRFYPFLSstywfNPALLLTASLTMLMAGLSAMTECDMKKIIALSTLSQLGVMMASLgLGMP 291

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 199 SLTILNLLIYLMLTITMFTMLNINTNTTT-----LTLSNLWNKNPMITLAILISLLSLGGLPPLTGFLPKWMIVQEFTKN 273
Cdd:MTH00207 292 KLALFHLITHALFKALLFVCAGSLIHSHHhsqdlRTMGNLTNQMPLTTSCLLIANLALCGSPFLSGFYSKDLILESSLFY 371

                        250
                 ....*....|...
gi 745999946 274 NNIVMATIMAIMA 286
Cdd:MTH00207 372 PHNSLMILMIFLA 384
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 98-211 1.88e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 39.90  E-value: 1.88e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  98 IIIALMMKLGMAPFHFWVPEV-----TQGVTLIVGMLL-LTWQKLAPISIMLQIYSSMNLN-VLLPFALLSILVGGWGGL 170
Cdd:MTH00226 236 IFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAGILLkLGGYGLVRLSWPILPLGAQNLApAVIAMGIVGIVYGSFATC 315

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|.
gi 745999946 171 NQTQLRKILAYSSIAHMGwMMAILMYCPSLTILNLLIYLML 211
Cdd:MTH00226 316 RQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIML 355
ndhB CHL00049
NADH dehydrogenase subunit 2
 51-297 1.98e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.99  E-value: 1.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  51 RSTEAATKYFLTQATASMLLMMTIV----ISAMNTGQWNI------TNMHNSLISFT----IIIALMMKLGMAPFHFWVP 116
Cdd:CHL00049 159 RSNEATMKYLLMGGASSSILVYGFSwlygLSGGEIELQEIvnglinTQMYNSPGISIalifITVGIGFKLSLAPFHQWTP 238

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 117 EVTQGVTLIVGMLLLTWQKLAPISIMLQI------YSSMNLNVLLP-FALLSILVGGWGGLNQTQLRKILAYSSIAHMGW 189
Cdd:CHL00049 239 DVYEGSPTPVVAFLSVTSKVAASALATRIfdipfyFSSNEWHLLLEiLAILSMILGNLIAITQTSMKRMLAYSSIGQIGY 318

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 190 MM-AILMYCPSLTILNLLIYLMLTITMFTMLNINTNTTTLTLSN--------LWNKNPMITLAILISLLSLGGLPPLTGF 260
Cdd:CHL00049 319 VIiGIIVGDSNDGYASMITYMLFYIFMNLGTFACIVLFGLRTGTdnirdyagLYTKDPFLALSLALCLLSLGGIPPLAGF 398

                        250       260       270
                 ....*....|....*....|....*....|....*..
gi 745999946 261 LPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLI 297
Cdd:CHL00049 399 FGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
50-191 2.32e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 39.68  E-value: 2.32e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  50 PRSTEAATKYFLTQATASMLLMMTIV----ISAMNTGQWNITNMHN------SLISFTIIIALMMKLGMAPFHFWVPE-- 117
Cdd:PRK06473 153 QRRGYAATKFLLYTAISGILILVSFLglvwLSGASSFDYEPLRSHTlplstqLLLLAPILVGFGIKIPLVPFHTWLPDah 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 118 ---------VTQGVTLI----------VGMLLLTWQKLAPIsimlqiyssmnlnvLLPFALLSILVGGWGGLNQTQLRKI 178
Cdd:PRK06473 233 veastpvsvLLAGVLLKlgtygllrfgVGLFPEAWVYLAPW--------------LATWAVVSVLYGASCAIAQKDMKKM 298

                        170
                 ....*....|...
gi 745999946 179 LAYSSIAHMGWMM 191
Cdd:PRK06473 299 VAYSSIGHMGYIL 311
PRK12644 PRK12644
putative monovalent cation/H+ antiporter subunit A; Reviewed
 98-194 5.28e-03

putative monovalent cation/H+ antiporter subunit A; Reviewed


Pssm-ID: 237154 [Multi-domain]  Cd Length: 965  Bit Score: 38.75  E-value: 5.28e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  98 IIIALMMKLGMAPFHFWVPE-----------------VTQGVTLIVgmllltwqKLAPISIMLQIYssmnLNVLLPFALL 160
Cdd:PRK12644 209 ILVGALSKSAIVPFHFWLPGamaaptpvsaylhaaamVKAGIYLVA--------RLAPGFADVPVW----RPTVLVLGLA 276

                         90       100       110
                 ....*....|....*....|....*....|....
gi 745999946 161 SILVGGWGGLNQTQLRKILAYSSIAHMGWMMAIL 194
Cdd:PRK12644 277 TMLLGGWRALRQHDLKLILAYGTVSQLGFLTVLV 310
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 100-211 5.74e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 38.49  E-value: 5.74e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 100 IALMMKLGMAPFHFWVPEV-----TQGVTLIVGMLL---------LTWQklapisiMLQIYSSMNLNVLLPFALLSILVG 165
Cdd:MTH00217 214 LSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLLklggygfirFSWP-------LLPEASEYFSPLIQTLSLLAIIYG 286

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*...
gi 745999946 166 GWGGLNQTQLRKILAYSSIAHMGWMMAILMycpSLTILNLL--IYLML 211
Cdd:MTH00217 287 SLTTCRQVDLKRIIAYSSVAHMGLVTLGIF---SHTIQGLVaaIFLML 331
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
34-299 6.44e-03

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 38.09  E-value: 6.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946  34 EINMLAIIPILVKKINPRSTEAATKYFLTQATASMLLMMTIVISAMNTGQWNITNMHNSLI-----------SFTIIIAL 102
Cdd:PRK06277 130 EIAAIVQVGLVIASGTEEAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNITDIHNALLvnptspviyggLLLLIFGL 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 103 MMKLGMAPFHFWVPEVTQGVTLIVGMLLLTWQKLAPISIMLQIYSSMNLNVLLP--------FALLSILVGGWGGLNQTQ 174
Cdd:PRK06277 210 LYGSGLPPFHTIKSDIYAKAKPFGSALLQTFSKFVLVALMLVIFKLFGGLSYFPsaqgvliaLSVLAMVFGVVMALLQTD 289

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999946 175 LRKILAYSSIAHMGWMMAILMYCPSLTI-------LNLLIYL-MLTITMFTMLNINTNTTTLTLSNLWNKNPMITLAILI 246
Cdd:PRK06277 290 YKRLLAYHAISQGGYVAAGLALGTPLGIvagifhaINHVIYKsALFLGAGIVSYRTKTSNLRKLGGLLPVMPVVAFMVLC 369

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 745999946 247 SLLSLGGLPPLTGFLPKWMIVQEFTKNNNIVMATIMAIMALLNLYFYMRLIYS 299
Cdd:PRK06277 370 AKLAISGVPPFNGFQSKLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYL 422
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH