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Conserved domains on  [gi|745999820|ref|YP_009114628|]
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NADH dehydrogenase subunit 2 (mitochondrion) [Propithecus edwardsi]

Protein Classification

NADH dehydrogenase subunit 2( domain architecture ID 11475899)

NADH dehydrogenase subunit 2 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), which functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.90e-155

NADH dehydrogenase subunit 2; Provisional


:

Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 439.67  E-value: 1.90e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999820 321 KFTLFLSPLITLST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.90e-155

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 439.67  E-value: 1.90e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999820 321 KFTLFLSPLITLST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 1.01e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.35  E-value: 1.01e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  18 MLTMISS-HWLLIWMGLEMNMLAIIpILA--KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG1007  115 MMLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALA 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  95 TLT------------IIIALTMKLGMTPFHFWIPEVTQG----VTL-------TAGMLLLtwqklapISIMLQIYPSMNT 151
Cdd:COG1007  194 AGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAAL-------LRLLVEAFPGLAA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 152 NILLTFALLSAL---VGGWGGLNQTQLRKILAYSSIAHMGWM-VAVLTFCP---SLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:COG1007  267 DWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVILLLSR 346

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999820 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:COG1007  347 KGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 1.31e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 101.18  E-value: 1.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   13 IFTGTMLTMISSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHN 91
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   92 LLTTLT------------IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSM-------NTN 152
Cdd:TIGR01770 191 FLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQI 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLML----TITLFTML------NVN 222
Cdd:TIGR01770 271 FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsllrsyKDE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 745999820  223 TSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:TIGR01770 351 WIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 1.09e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 1.09e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   23 SSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT------- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   95 ----TLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLL-TWQKLAPISIMLQIYPSMN-----TNILLTFALLSALV 164
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  165 GGWGGLNQTQLRKILAYSSIAHMGWMVAVL----TFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI-----LWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrdyggLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 745999820  236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
 
Name Accession Description Interval E-value
ND2 MTH00105
NADH dehydrogenase subunit 2; Provisional
 1-334 1.90e-155

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177167 [Multi-domain]  Cd Length: 347  Bit Score: 439.67  E-value: 1.90e-155
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00105   1 MNPLILIIIYLTLFLGTMITMISSHWLLAWIGLEMNMLAIIPILMKKHNPRSTEAATKYFLTQATASMLLMMAIIINLMY 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00105  81 SGQWTITKLTNPTASTLMTIALAMKLGLAPFHFWVPEVTQGIPLSSGMILLTWQKLAPLSILYQISPSINPNLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00105 161 SILIGGWGGLNQTQLRKILAYSSIAHMGWMTAILPYNPTLTLLNLLIYIIMTLTMFMLLMLNSSTTTLSLSHTWNKTPLM 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00105 241 TSLILLTLLSLGGLPPLTGFMPKWMIIQELTKNNNIILPTLMAITALLNLYFYMRLIYSTSLTMFPSTNNMKMKWQFENT 320

                        330
                 ....*....|....
gi 745999820 321 KFTLFLSPLITLST 334
Cdd:MTH00105 321 KPMTLLPTLIILST 334
ND2 MTH00135
NADH dehydrogenase subunit 2; Provisional
 1-334 3.05e-115

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177193 [Multi-domain]  Cd Length: 347  Bit Score: 337.55  E-value: 3.05e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00135   1 MNPYVLTILLFSLGLGTTLTFASSHWLLAWMGLEINTLAIIPLMAQHHHPRAVEATTKYFLTQATAAAMILFASTTNAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSmNTNILLTFALL 160
Cdd:MTH00135  81 TGQWDIQQMSHPLPTTMITLALALKIGLAPLHFWLPEVLQGLDLTTGLILSTWQKLAPFALILQIAPT-NPTLLITLGLT 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00135 160 STLVGGWGGLNQTQLRKILAYSSIAHLGWMILVLQFSPSLTLLALLTYIIMTSSAFLTFKLNSSTKINTLATSWTKAPAL 239

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00135 240 TALTPLILLSLGGLPPLTGFMPKWLILQELTKQDLPLTATLAALSALLSLYFYLRLSYAMTLTISPNTLNGTTPWRLPST 319

                        330
                 ....*....|....
gi 745999820 321 KFTLFLSPLITLST 334
Cdd:MTH00135 320 QLTLPLAISTTATL 333
ND2 MTH00070
NADH dehydrogenase subunit 2; Provisional
 1-334 1.51e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177142 [Multi-domain]  Cd Length: 346  Bit Score: 315.71  E-value: 1.51e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00070   1 MSPYALSILLSSLALGTMITLSSNHWFLAWMGLEINTLAIIPLMTKTHHPRATEAATKYFLTQASASALILFSSTINAWF 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00070  81 TGEWTIMNMQTPLPTIMLTIALMMKLGIAPFHFWLPEVLQGLDLTTGLILSTWQKLAPMALLIQISHLLNSNLLIIMGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00070 161 STLIGGWGGLNQTQLRKIMAYSSIAHLGWMIIILTFSPHLTLLNLLIYLIMTSSMFLMLMNLNSTNINKLSSSWSKNPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLqPT 320
Cdd:MTH00070 241 TSMMMLTLLSLGGLPPTTGFIPKWLILQELTKQNLTTLATLMALSALLSLFFYLRLSYAMSLTTSPNTSNSKLYWRF-KN 319

                        330
                 ....*....|....
gi 745999820 321 KFTLFLSPLITLST 334
Cdd:MTH00070 320 KTNNLLSLTIILSL 333
ND2 MTH00112
NADH dehydrogenase subunit 2; Provisional
 1-334 9.21e-106

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214423 [Multi-domain]  Cd Length: 346  Bit Score: 313.68  E-value: 9.21e-106
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00112   1 MNPHAKLIITTSLILGTIITISSNHWLMAWTGLEINTLAIIPLISKPHHPRATEAATKYFLTQAAASALILFSSTTNAWN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00112  81 TGQWDITQLTNPTSCTLLTLALAMKLGLAPFHFWLPEVLQGSTTTTALILSTWQKLAPLTLLLMTSNSLNPTLLLTLAIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00112 161 STLIGGWGGLNQTQLRKIMAFSSIAHLGWMIAIITYSPKLTLLTFYIYILMTTPMFLTLNTTSTKTLKDMMTSWTKSPTL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00112 241 NTTLMLTLLSLAGLPPLTGFMPKWLILQELTKQNMTPTATIMAMLSLLSLFFYLRLTYISTITLPPNTTNMMMKWRTKPK 320

                        330
                 ....*....|....
gi 745999820 321 KFTLfLSPLITLST 334
Cdd:MTH00112 321 KNTL-TATLTTLST 333
ND2 MTH00041
NADH dehydrogenase subunit 2; Validated
 1-307 2.11e-78

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 177116 [Multi-domain]  Cd Length: 349  Bit Score: 243.68  E-value: 2.11e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00041   1 MNRNVLIFLITSIILGTIIVISSNHWFLIWLGLELNTLSIIPILSSNFSPRSVEATIKYFLVQAFSAAILLNGALIQAWL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00041  81 SGSWSINGPLNTLSSIIITLALALKLGLAPCHFWFPDVLQGLPFLQGLIIATWQKIAPLILLISISNLLNSNILILCGIL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00041 161 SVLVGGWGGLNQTQTRKILAFSSIAHLGWIIITSAYSPNASIIMFLIYIIINTSIFLIGNNFSLSTLSHLNKLSQLNPIS 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPT 307
Cdd:MTH00041 241 AFLFILSILSLGGLPPLTGFLNKFISLYCLIQNNSILISIILIIGSLLSLFFYLRISFNTSLTLFPQ 307
ND2 MTH00200
NADH dehydrogenase subunit 2; Provisional
 1-327 2.51e-78

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177246 [Multi-domain]  Cd Length: 347  Bit Score: 243.34  E-value: 2.51e-78
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00200   1 MSPLILPLFILSLGLGTLLTFSSSHWFLIWLGLEINTLAIIPLLIKQHHPRKVEATTKYFIIQATASALLLFGGLLNAWT 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TGQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALL 160
Cdd:MTH00200  81 SGQWGISEMLGPLSETLILLALALKLGLAPGHFWVPDVLQGLSLQTGLILSTWQKLAPFALLIQLAPALNSNILLLLGLL 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00200 161 SVLVGGWGGLNQTQLRKILAYSSIAHLGWLLSGLVYSPNLALLYLLLYVIITLTVFLLLNLLNSTKINSLSSSKTKNPIL 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00200 241 SMLLGLTLLSLGGLPPLTGFFPKWLILQELSKQGLFIYATILLLGSLLSLFFYLRLSYLTLLTLSPNQINMMSSWRTKSN 320


                 ....*..
gi 745999820 321 KFTLFLS 327
Cdd:MTH00200 321 SNLLVGL 327
ND2 MTH00144
NADH dehydrogenase subunit 2; Provisional
 10-315 1.31e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214432 [Multi-domain]  Cd Length: 328  Bit Score: 168.91  E-value: 1.31e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  10 ITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTni 89
Cdd:MTH00144  10 LFLMVMGTLLSLSSSHWLGVWVGLEINLIGFLPLLVYKKKSSESESVVKYFIIQSLGSSLLIFGSLIMYNLSFSWFSM-- 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  90 hnllttLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNT-NILLTFALLSALVGGWG 168
Cdd:MTH00144  88 ------SLLLLGLCLKLGLFPFHFWVPSVMAGLSWLSCFLLLTWQKVAPLFLLSNFLDLYWLaYLLCVISVLSALVGSIG 161

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 169 GLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILwNKNPTITLMILTSL 248
Cdd:MTH00144 162 GLNQTQVRALLAYSSISHTGWMLVAILHGSWLMWMYFLIYIVSSGFLFFSLWSGDSGSMKDLGSL-KPSYKTGLSIISLL 240

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 745999820 249 LSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKW 315
Cdd:MTH00144 241 LSLGGLPPFLGFCSKLLVLISSMESSPLLLILLLLLGSLISLFFYLSVFFSSFLSSSKSKKSNSSKV 307
ND2 MTH00160
NADH dehydrogenase subunit 2; Provisional
 1-333 1.58e-49

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214442 [Multi-domain]  Cd Length: 335  Bit Score: 168.85  E-value: 1.58e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   1 MNPIALMPIITTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMY 80
Cdd:MTH00160   2 MMNSSKLLFLSTLIMGTLISISSNSWFGAWMGLEINLLSFIPLISNKKNLMSSESSLKYFLIQALASIILLFSIILNMLN 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  81 TgqwnvtNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIypsMNTNILLTFALL 160
Cdd:MTH00160  82 L------MLFNNISSMLINSSLLLKLGAAPFHFWFPEVMEGLSWINCFILMTWQKIAPLILLSYL---INNNFIIIIIIL 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 161 SALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTI 240
Cdd:MTH00160 153 SAIIGAIGGLNQTSLRKILAYSSINHLGWMLSSMMISENLWLIYFLIYSIISLSIILLFNKFNIFFLNQLFNSNNKSKKI 232

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 241 TLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPT 320
Cdd:MTH00160 233 KFLLFLNLLSLGGLPPFLGFLPKWIIIQLLISNNMFFLLFILIMSSLITLYFYLRISYSSLMLNYNKNKWNLKKKKNKFS 312

                        330
                 ....*....|...
gi 745999820 321 KFTLFLSPLITLS 333
Cdd:MTH00160 313 LILNFLSFISLFG 325
ND2 MTH00011
NADH dehydrogenase subunit 2; Validated
 11-329 1.94e-45

NADH dehydrogenase subunit 2; Validated


Pssm-ID: 164587 [Multi-domain]  Cd Length: 330  Bit Score: 158.02  E-value: 1.94e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  11 TTIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTnih 90
Cdd:MTH00011  13 STMTLGTLMALSSNNWLFLWMGMELNLLSFVPLMTSSKMNQESEAAVKYFLAQALGSGLLLLGMTMMWSFPSLLKNI--- 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  91 nllTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALLSALVGGWGGL 170
Cdd:MTH00011  90 ---TALMLLVSLMLKLGMAPCHFWFPSVMSSISWTLCLILSTWQKIAPLSILFFFTSHNILPMMTSMAAMSALAGGLGGM 166

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 171 NQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLS 250
Cdd:MTH00011 167 NQTQLRPLLAYSSIGHMGWMTMISVFSPSMAILYFMTYIIITTPLMLLFAYLNAFSTKFNSKISSMSQTTSMSLFIMLLS 246

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999820 251 LGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYStSLTMFPTSNNMKMKWQLQPTKFTLFLSPL 329
Cdd:MTH00011 247 LGGLPPFTGFMPKLMAIETLTSNSMILILLVLIVGSLMNLFYYLNLIFN-FMYLSPTFSSLKSAPYEPKTKILISMCTL 324
ND2 MTH00197
NADH dehydrogenase subunit 2; Provisional
 12-329 3.65e-37

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177244 [Multi-domain]  Cd Length: 323  Bit Score: 135.96  E-value: 3.65e-37
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  12 TIFTGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMytgqwnvTNIHN 91
Cdd:MTH00197   6 IIFGGVLFSLSSSNWFLVWIGMELNLIGFIPLLSQNKSITENEGAMKYFLFQEFGSALLLMGGSLSFS-------NLYLS 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  92 LLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNtnILLTFALLSALVGGWGGLN 171
Cdd:MTH00197  79 LLSVVLVILGLLLKLGAFPFHFWVPSVMESLSWFNCFLLATWQKLAPLLILAFNSSSFM--GLLICSVLSSLIGGIGGMN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 172 QTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLSL 251
Cdd:MTH00197 157 QSNIRQLLAYSSIGHTGWMLMSLVYSPSIFMLYYLIYFVIMFMLFLFLSKNNLSSLNQQYSNPESMSSNLVFLGLSFLSL 236

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 745999820 252 GGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLFLSPL 329
Cdd:MTH00197 237 GGLPPLSGFFLKWLILTSLLSSNISLITFMLILSTCFSLYYYLSLAYKSLILSNWMINFLMKINLLYSGLFILLMMML 314
ND2 MTH00199
NADH dehydrogenase subunit 2; Provisional
 8-298 2.96e-27

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177245 [Multi-domain]  Cd Length: 460  Bit Score: 111.26  E-value: 2.96e-27
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   8 PIITTIFTGTMLTMISS-HWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWN 85
Cdd:MTH00199 100 PILILIVALGSLLLVSSiNWLSIYLAIELQTLTLFILVAlKRDSAYSTEAGLKYFVLGAVSSGLFLFGCALLYGLTGETS 179

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  86 VTNIHNLLTT----LTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSmnTNILLTFALLS 161
Cdd:MTH00199 180 IQGINSILTGdvgkILITISLLFKLSAAPFHMWAPDVYEGAPTITTALLATVPKIGVFSILVQIGPV--TNVVLICAVLS 257

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 162 ALVGGWGGLNQTQLRKILAYSSIAHMG---WMVAVLTFCP-SLTILNLLIYLMLTITLFT-MLNVNTSTTTLTLSI-LWN 235
Cdd:MTH00199 258 IIYGAIGALNQTKIKRLLAYSGIGHMGfilFGVAIGSFESiQASLIYMIIYVIMSICSFSiILSLKLTKGLIVEVSgLSR 337

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 745999820 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:MTH00199 338 KNPVIALTLALTFLSIAGIPPLAGFLSKWLILLSGVSSGYYLICIIAVLSSVIAGVYYVRVVQ 400
NuoN COG1007
NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH: ...
 18-298 1.01e-23

NADH:ubiquinone oxidoreductase subunit 2 (chain N) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 2 (chain N) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440631 [Multi-domain]  Cd Length: 473  Bit Score: 101.35  E-value: 1.01e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  18 MLTMISS-HWLLIWMGLEMNMLAIIpILA--KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG1007  115 MMLMASAnDLLTLFLGLELLSLSLY-VLVafRRDDRRSSEAALKYFLLGALSSGFLLYGISLLYGATGSLNLAGIAAALA 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  95 TLT------------IIIALTMKLGMTPFHFWIPEVTQG----VTL-------TAGMLLLtwqklapISIMLQIYPSMNT 151
Cdd:COG1007  194 AGGanspllllglvlVLAGLAFKLSAVPFHMWTPDVYEGaptpVTAflatapkIAAFAAL-------LRLLVEAFPGLAA 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 152 NILLTFALLSAL---VGGWGGLNQTQLRKILAYSSIAHMGWM-VAVLTFCP---SLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:COG1007  267 DWQLLLAVLAVLsmtVGNLAALAQTNVKRMLAYSSIAHAGYLlLGLAAGTPlgvSAALFYLLAYLFMNLGAFAVILLLSR 346

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 745999820 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIY 298
Cdd:COG1007  347 KGGEAEEIedlagLARRSPLLALAMTIFLLSLAGIPPTAGFFGKFYVFSAAVEAGLYWLAVIAVLNSVISAYYYLRVVK 425
NDH_I_N TIGR01770
proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th ...
 13-297 1.31e-23

proton-translocating NADH-quinone oxidoreductase, chain N; This model describes the 14th (based on E. coli) structural gene, N, of bacterial and chloroplast energy-transducing NADH (or NADPH) dehydrogenases. This model does not describe any subunit of the mitochondrial complex I (for which the subunit composition is very different), nor NADH dehydrogenases that are not coupled to ion transport. The Enzyme Commission designation 1.6.5.3, for NADH dehydrogenase (ubiquinone), is applied broadly, perhaps unfortunately, even if the quinone is menaquinone (Thermus, Mycobacterium) or plastoquinone (chloroplast). For chloroplast members, the name NADH-plastoquinone oxidoreductase is used for the complex and this protein is designated as subunit 2 or B. This model also includes a subunit of a related complex in the archaeal methanogen, Methanosarcina mazei, in which F420H2 replaces NADH and 2-hydroxyphenazine replaces the quinone. [Energy metabolism, Electron transport]


Pssm-ID: 273795 [Multi-domain]  Cd Length: 468  Bit Score: 101.18  E-value: 1.31e-23
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   13 IFTGTMLTMISSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHN 91
Cdd:TIGR01770 111 ALLGIFLLVSSNDLLSIYLGLELQSLCFYVLAGlKRKSRFSTEAGLKYFILGAFSSGLLLFGISLIYGFTGSLNFEDLLL 190

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   92 LLTTLT------------IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSM-------NTN 152
Cdd:TIGR01770 191 FLSNGMlnisllllgivlILVGLLFKLSAVPFHMWVPDVYEGAPTPVTAFFSIVPKIAIFAVFLRLFLYIlfgfseaWQI 270

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLML----TITLFTML------NVN 222
Cdd:TIGR01770 271 FLAIIAFLSMLIGNFGALAQKKVKRLLAYSSISHVGYILIGLLAGTLEGIKAVLFYIFIyalmSLGAFGVLsllrsyKDE 350

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 745999820  223 TSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:TIGR01770 351 WIEYISDFAGLFKTNPILAILILIFMFSLAGIPPLAGFFGKFYVFFALLKSGLYWLAVIAVLTSVIGAFYYLRVV 425
ND2 MTH00196
NADH dehydrogenase subunit 2; Provisional
 16-297 3.74e-23

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214453 [Multi-domain]  Cd Length: 365  Bit Score: 98.56  E-value: 3.74e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  16 GTMLTMISSHWLLIWMGLEMNMLAI-IPILAKKTNPRSTEAATKYFLTQATASMLLMMTIV-------------INAMYT 81
Cdd:MTH00196   5 GILCLISSSNWLSVYLAIELQTLSLfILIAQNRGSGYSAEAGLKYFVLGALSSGLFLFGCAllcgttgglhlsyINLVLN 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  82 GQWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPsmNTNILLTFALLS 161
Cdd:MTH00196  85 SGQSFSSVSVPIGYLLIIVALLFKLSVAPFHMWAPDVYEGAPTKTTALLAIVPKLGIFSILVSIGL--NVNILLIGGLFS 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 162 ALVGGWGGLNQTQLRKILAYSSIAHMG---WMVAVLTF-CPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI--LWN 235
Cdd:MTH00196 163 LFVGAIGALNQTKIKRLLAYSGIGHMGfvlWGIEIGSFeSIQASLVYLFIYIIMSICVFSIILALNVYKNLIIEFsgLSR 242

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 745999820 236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:MTH00196 243 RLPILAITLALTFLSIAGIPPLVGFLGKWLILLSGVVYQYYLIFLLAVFCSVIAGVYYVRIV 304
Proton_antipo_M pfam00361
Proton-conducting membrane transporter; This is a family of membrane transporters that ...
 23-286 1.09e-22

Proton-conducting membrane transporter; This is a family of membrane transporters that inlcudes some 7 of potentially 14-16 TM regions. In many instances the family forms part of complex I that catalyzes the transfer of two electrons from NADH to ubiquinone in a reaction that is associated with proton translocation across the membrane, and in this context is a combination predominantly of subunits 2, 4, 5, 14, L, M and N. In many bacterial species these proteins are probable stand-alone transporters not coupled with oxidoreduction. The family in total represents homologs across the phyla.


Pssm-ID: 425636 [Multi-domain]  Cd Length: 291  Bit Score: 96.23  E-value: 1.09e-22
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   23 SSHWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT------- 94
Cdd:pfam00361   1 ANDLLLMYLGWEAVLLPSYLLIGyWGKSPRSSEAGMKYFLLTLLGSSILLFGISLMYNYTGTLSFDELSKALTgglnssg 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   95 ----TLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLL-TWQKLAPISIMLQIYPSMN-----TNILLTFALLSALV 164
Cdd:pfam00361  81 llllFLLILVGFLFKSAQVPFHTWLPDAYEGAPTPVSALLAaTLVKAGGYGLIRRSLLYLPsspfiQQILLILAIISMLL 160

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  165 GGWGGLNQTQLRKILAYSSIAHMGWMVAVL----TFCPSLTILNLLIYLMLTITLFTMLNVNTSTTTLTLSI-----LWN 235
Cdd:pfam00361 161 GSLAALVQTDIKRLLAYSSISHMGYMLIALgagtIYGIQAAIFHLLTHGLFSAGLFLCAGSVIYRRVHTRNIrdyggLAK 240

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|.
gi 745999820  236 KNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITA 286
Cdd:pfam00361 241 TMPILALVFLVAMLSLAGLPPTAGFLGKFLILAAAVAASWIFLVLAGVVGS 291
PRK05777 PRK05777
NADH-quinone oxidoreductase subunit NuoN;
15-332 6.31e-21

NADH-quinone oxidoreductase subunit NuoN;


Pssm-ID: 235603 [Multi-domain]  Cd Length: 476  Bit Score: 93.35  E-value: 6.31e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  15 TGTMLTMISS-HWLLIWMGLEMNMLAIIPILA-KKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNL 92
Cdd:PRK05777 113 LLGMMVMVSAnDLLTLFLGLELLSLPLYALAAlRRDRRRSLEAAIKYFVLGALASGFLLYGMSLLYGATGSLSFAGIAKA 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  93 LTTLT------------IIIALTMKLGMTPFHFWIPEVTQG-----------VTLTAGM-LLLTWQKLAPISIMLQIYPs 148
Cdd:PRK05777 193 LADGSgnsllllfglvfLLVGLAFKLSAVPFHMWTPDVYEGaptpvtaflatAPKIAAFaVLLRLLVVAFGGLSEDWQQ- 271

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 149 mntnILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWM----VAVLTFCPSLTILNLLIYLMLTITLFTMLNVNTS 224
Cdd:PRK05777 272 ----VLAIIAIASMLVGNLAALSQTNIKRLLAYSSIAHAGYLlvglAAGTAEGYSAVLFYLLAYLFMTLGAFGVISLLRR 347

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 225 TTTLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYs 299
Cdd:PRK05777 348 KGGEAESIsdfagLSKRSPLLAAVMTIFMLSLAGIPPTAGFWGKFYVFEAAVEAGLWWLAVIGVLNSAIGAFYYLRVIK- 426

                        330       340       350
                 ....*....|....*....|....*....|....*
gi 745999820 300 tslTMF--PTSNNMKMKWQLQPTKFTLFLSPLITL 332
Cdd:PRK05777 427 ---LMYfdEPPRDAPVNWPLSAGGAVLSVSALLVL 458
HyfB COG0651
Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy ...
 15-301 1.39e-14

Formate hydrogenlyase subunit 3/Multisubunit Na+/H+ antiporter, MnhD subunit [Energy production and conversion, Inorganic ion transport and metabolism];


Pssm-ID: 440416 [Multi-domain]  Cd Length: 430  Bit Score: 74.03  E-value: 1.39e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  15 TGTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLT 94
Cdd:COG0651  118 AGMNGAFLTGDLFNLFVFFEVMLLASYGLVALGGTKEALRAGLKYLILNLVGSALFLLGVGLLYGATGTLNMADLAARLA 197

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  95 TLT----------IIIALTMKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLtwqklapISIMLQIYPSMNTN- 152
Cdd:COG0651  198 ELDpglllaafalLLVGFGIKAALFPLHFWLPDaypaapspvsaLLSGLLTKVGVYAI-------LRVLTLLFGADPALf 270

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 153 ---ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYL---MLTITLFTMLNVNTSTT 226
Cdd:COG0651  271 lgtLLLVLGLLTMLVGALGALAQRDLKRLLAYSSVSQIGYILLGLGLGTPLGLAGALFHLlnhALAKALLFLAAGAIERA 350

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 227 TLTLSI-----LWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTS 301
Cdd:COG0651  351 TGTRDLdklggLGKRMPLTAAAFLIGALALAGLPPLSGFVSKWLLLQAALEAGAWLLAAVLLLSSLLTLAYFVRIFGRAQ 430
ND2 MTH00198
NADH dehydrogenase subunit 2; Provisional
 16-219 9.07e-13

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 214454 [Multi-domain]  Cd Length: 607  Bit Score: 69.12  E-value: 9.07e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  16 GTMLTMISSHWLLIWMGLEMNMLAIIPILAKKTNPRST---------EAATKYFLTQATASMLLMMTIVINAMYTGQ--- 83
Cdd:MTH00198 200 GGLLLIESANWLTIYLALEFQTLALFILAGEGSQPGSHfpspgntppESGLKYWILGAMSSGFYLFGCALYFGFTGNegm 279

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  84 --------WNVTNI---HNLLTTLTIIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYpsMNTN 152
Cdd:MTH00198 280 lgtilsatLETTNIelrQGSLGYLFITVAILFKLAAAPFHMWTPDVYEGAPTPTTALIAIIPKFTVYILLTSLV--ITSK 357

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 745999820 153 ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILN----LLIYLMLTITLFTML 219
Cdd:MTH00198 358 LLLSVAIISLVVGAFGALNQTRIKRLLAYSGIGHIGFILIGVSAGTYESLQAswtyAVTYLVSALASFTVI 428
NuoM COG1008
NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH: ...
 55-192 7.71e-10

NADH:ubiquinone oxidoreductase subunit 4 (chain M) [Energy production and conversion]; NADH:ubiquinone oxidoreductase subunit 4 (chain M) is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440632 [Multi-domain]  Cd Length: 488  Bit Score: 59.71  E-value: 7.71e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  55 AATKYFLTQATASMLLMMTIVINAMYTGQWNvTNIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEV----- 118
Cdd:COG1008  162 AAIKFFLYTLAGSLLMLVAILALYFLAGALT-FDIAELAAAplpltaqlllfLAFFIAFAVKVPMFPFHTWLPDAhveap 240

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 119 TQGVTLTAGMLLltwqKLAP---ISIMLQIYP---SMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVA 192
Cdd:COG1008  241 TAGSVLLAGVLL----KMGGyglLRFALPLFPeasAYFAPLLAALGVIGIIYGALVALAQTDLKRLIAYSSVSHMGFVLL 316
PRK02504 PRK02504
NAD(P)H-quinone oxidoreductase subunit N;
9-297 1.24e-08

NAD(P)H-quinone oxidoreductase subunit N;


Pssm-ID: 235044 [Multi-domain]  Cd Length: 513  Bit Score: 56.21  E-value: 1.24e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   9 IITTIFTGTMLTMISSHWLLIWMGLEMnmLAIIPILAK---KTNPRSTEAATKYFLTQATAS-MLLMMTIVINAMYTGQW 84
Cdd:PRK02504 115 ILLTATLGGMFLSGATELVMIFISLET--LSIASYLLTgymKRDPRSNEAALKYLLIGAASSaIFLYGSSLLYGLSGGST 192

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  85 NVTNIHNLLT---TLTIIIALTM-------KLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLA----PISIMLQIYPSMN 150
Cdd:PRK02504 193 QLSAIALALItspSLGLALALVFviagiafKISAVPFHQWTPDVYEGSPTPVVAFLSVGSKAAgfalAIRLLVTAFPSFD 272

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 151 TNILLTF---ALLSALVGGWGGLNQTQLRKILAYSSIAHMGW----MVAVLTFCPSLTILNLLIYLMLT------ITLFT 217
Cdd:PRK02504 273 EQWKLLFtalAILSMVLGNVVALAQTSMKRMLAYSSIGQAGFvmigLVAGTEAGYASMVFYLLAYLFMNlgafacVILFS 352

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 218 MLNVNTSTTTLTLsiLWNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:PRK02504 353 LRTGTDQISDYAG--LYQKDPLLTLGLSLCLLSLGGIPPLAGFFGKIYLFWAGWQAGLYLLVLVGLVTSVISIYYYIRVI 430
NADH_dehy_S2_C pfam06444
NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region ...
 291-334 3.40e-08

NADH dehydrogenase subunit 2 C-terminus; This family consists of the C-terminal region specific to the eukaryotic NADH dehydrogenase subunit 2 protein and is found in conjunction with pfam00361.


Pssm-ID: 461914 [Multi-domain]  Cd Length: 51  Bit Score: 49.18  E-value: 3.40e-08
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|....
gi 745999820  291 YFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLFLSPLITLST 334
Cdd:pfam06444   1 FFYLRLSYSTTLTLFPNTNNSKMKWRFNSTKNTLLLPTLTTLSI 44
NuoL COG1009
Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ ...
 48-194 1.10e-07

Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit [Energy production and conversion]; Membrane H+-translocase/NADH:ubiquinone oxidoreductase subunit 5 (chain L)/Multisubunit Na+/H+ antiporter, MnhA subunit is part of the Pathway/BioSystem: NADH dehydrogenase


Pssm-ID: 440633 [Multi-domain]  Cd Length: 608  Bit Score: 53.23  E-value: 1.10e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  48 TNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNI---------HNLLTTLTIII---ALTmKLGMTPFHFWI 115
Cdd:COG1009  156 EKPSARRAARKAFLVTRVGDLGLLLGILLLGAIAGTLNFSELlaaaptilsSPLLTLILLLLllgAFG-KSAQFPLHFWL 234

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 116 PEVTQGVT-----------LTAGMLLLTwqKLAPISIMLQIYpsmnTNILLTFALLSALVGGWGGLNQTQLRKILAYSSI 184
Cdd:COG1009  235 PDAMEGPTpvsallhaatmVKAGVYLLA--RLSPLFALSPVW----LTVVAIIGAITALFAALIALAQTDIKRVLAYSTV 308

                        170
                 ....*....|
gi 745999820 185 AHMGWMVAVL 194
Cdd:COG1009  309 SQLGYMFLAL 318
NDH_I_M TIGR01972
proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th ...
 55-191 1.64e-07

proton-translocating NADH-quinone oxidoreductase, chain M; This model describes the 13th (based on E. coli) structural gene, M, of bacterial NADH dehydrogenase I, as well as chain 4 of the corresponding mitochondrial complex I and of the chloroplast NAD(P)H dehydrogenase complex. [Energy metabolism, Electron transport]


Pssm-ID: 273903 [Multi-domain]  Cd Length: 481  Bit Score: 52.63  E-value: 1.64e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   55 AATKYFLTQATASMLLMMTIVINAMYTG---------QWNVTNIHNLLTTLTIIIALTMKLGMTPFHFWIPEV-TQGVTL 124
Cdd:TIGR01972 157 AAMKFFLYTLAGSLLMLLAILGLYFLGGgtfdllellNLPLPFGVQTWLFLAFFIAFAVKVPLFPLHTWLPDAhVEAPTA 236

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 745999820  125 TAGMLLLTWQKLAPISIM---LQIYPS---MNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMV 191
Cdd:TIGR01972 237 GSVILAGVLLKMGTYGFLrfnLPLFPDaslYFAPVLAALGVIAIIYGALIALAQTDIKRLIAYSSISHMGFVL 309
PRK05846 PRK05846
NADH:ubiquinone oxidoreductase subunit M; Reviewed
 55-191 2.24e-07

NADH:ubiquinone oxidoreductase subunit M; Reviewed


Pssm-ID: 235622 [Multi-domain]  Cd Length: 497  Bit Score: 52.13  E-value: 2.24e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  55 AATKYFLTQATASmlLMMTIVINAMYTGQWNVT---NIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEV-- 118
Cdd:PRK05846 162 AATKFFLYTLLGS--LLMLVAIIYLVVVYYNATgtfDIADLLNLplppgvqywlfLAFFIAFAVKMPMFPLHTWLPDAhv 239

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 119 ---TQGVTLTAGMLLltwqKLAP---ISIMLQIYPSMNTN---ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGW 189
Cdd:PRK05846 240 qapTAGSVLLAGILL----KMGAyglLRFSLPLFPDASHEfapIIITLGVIAIIYGALVALAQTDIKKLIAYSSISHMGF 315


                 ..
gi 745999820 190 MV 191
Cdd:PRK05846 316 VT 317
PRK08375 PRK08375
putative monovalent cation/H+ antiporter subunit D; Reviewed
 33-210 5.43e-07

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236251 [Multi-domain]  Cd Length: 487  Bit Score: 51.03  E-value: 5.43e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  33 LEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLL--------TTLTIIIALTM 104
Cdd:PRK08375 135 LEIMSLSSYALVAMGGDRRALAAARKYLIVGLIGSTFLLIGVGLLYGVTGTLNMADLAGALaenptvvtAFGFVLLALAL 214

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 105 KLGMTPFHFWIPEvTQGVTLTAGMLLL--TWQKlAPISIMLQIYPSMNT----------NILLTFALLSALVGGWGGLNQ 172
Cdd:PRK08375 215 KAAVFPLHTWLPR-AYPAAPPVVTALLsgLVTK-VAVYALIRIYFTVFGgdfrfalglgWLLAVLALLSMLVGSLAALGQ 292

                        170       180       190
                 ....*....|....*....|....*....|....*...
gi 745999820 173 TQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLM 210
Cdd:PRK08375 293 DDVKRVLAYSTVSQMGYILLGLALLTPLALAAGLLHLL 330
PRK12650 PRK12650
DUF4040 family protein;
9-194 2.16e-06

DUF4040 family protein;


Pssm-ID: 237158 [Multi-domain]  Cd Length: 962  Bit Score: 49.66  E-value: 2.16e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820   9 IITTIFTGTMLTMI-SSHWLLIWMGLEMNMLAIIPILAKkTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTGqwnVT 87
Cdd:PRK12650 114 LLMTAFMAAMLLLVlADDVVVLFVAWELVSLASFFLIAR-SGSGGEAGSIRTLILTFFGGLTLLAAVAIAATQTG---TT 189

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  88 NIHNLL--------TTLTIIIALTM------KLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTN- 152
Cdd:PRK12650 190 SLSGILhsdvwaekPGLTTVVAVLIavaaftKSAQFPFHFWLPEAMAAITPVSAFLHAAAVVKAGIYLLLRFSPVFHDVa 269

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*.
gi 745999820 153 ----ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVL 194
Cdd:PRK12650 270 vwnwLLIIVGMITALMGAVFAVQKTDLKKLTAYSTVSQLGWIVATI 315
PRK12561 PRK12561
NAD(P)H-quinone oxidoreductase subunit 4; Provisional
 55-188 4.65e-06

NAD(P)H-quinone oxidoreductase subunit 4; Provisional


Pssm-ID: 237137 [Multi-domain]  Cd Length: 504  Bit Score: 48.10  E-value: 4.65e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  55 AATKYFLTQATASMLLMMTIVINAMYTGQ--WNVTNIHN--------LLTTLTIIIALTMKLGMTPFHFWIP----EVTQ 120
Cdd:PRK12561 138 AATKFILYTALASIFILVAGLALALSGDTftFDLAELGAksyplaleLLLYAGFLIAFGVKLPIFPLHTWLPdahgEASA 217

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 745999820 121 GVTLTAGMLLLTWQKLAPISIMLQIYPsmntNILLTFALLSALVGG----WGGLN---QTQLRKILAYSSIAHMG 188
Cdd:PRK12561 218 PVSMILAGVLLKMGGYALIRFNVQMLP----DAHVYFAPALAILGVvniiYGALNafaQDNVKRRLAYSSVSHMG 288
PRK06473 PRK06473
NADH-quinone oxidoreductase subunit M;
27-190 1.43e-05

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 235810 [Multi-domain]  Cd Length: 500  Bit Score: 46.62  E-value: 1.43e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  27 LLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFLTQATASMLLMMTIVINAMYTG----QWNVTNIHNL------LTTL 96
Cdd:PRK06473 130 LLFFLFYELELIPLYLLIAIWGGQRRGYAATKFLLYTAISGILILVSFLGLVWLSGassfDYEPLRSHTLplstqlLLLA 209

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  97 TIIIALTMKLGMTPFHFWIPEV-----TQGVTLTAGMLLltwqKLAPISIM---LQIYPSMNTNI---LLTFALLSALVG 165
Cdd:PRK06473 210 PILVGFGIKIPLVPFHTWLPDAhveasTPVSVLLAGVLL----KLGTYGLLrfgVGLFPEAWVYLapwLATWAVVSVLYG 285

                        170       180
                 ....*....|....*....|....*
gi 745999820 166 GWGGLNQTQLRKILAYSSIAHMGWM 190
Cdd:PRK06473 286 ASCAIAQKDMKKMVAYSSIGHMGYI 310
PRK08376 PRK08376
putative monovalent cation/H+ antiporter subunit D; Reviewed
 54-190 1.94e-05

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 236252 [Multi-domain]  Cd Length: 521  Bit Score: 46.24  E-value: 1.94e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  54 EAATKYFLTQATASMLLMMTIvinAMYTGQWNVTNI----HNLLTTLTI---------IIALTMKLGMTPFHFWIPEVTQ 120
Cdd:PRK08376 172 EAGIKYMFVGSLASSMVLLGI---ALLYGQYGTLNMaylaVKMSENPTVvakialalfIAGLAMKSGAVPVHMWLPDAYP 248

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 745999820 121 GV--TLTAGMLLLTWQKLAPIS-IMLQIY-PSMNTN----ILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWM 190
Cdd:PRK08376 249 AApsSISAMLLVIKQAGLYALArVLFSIYgPAINLAtvgwVIIILGCLTMFVGVAMAVVQKDVKRLLAYHSVSQIGYM 326
PRK06277 PRK06277
energy conserving hydrogenase EhbF;
51-325 3.98e-05

energy conserving hydrogenase EhbF;


Pssm-ID: 235767 [Multi-domain]  Cd Length: 478  Bit Score: 45.02  E-value: 3.98e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  51 RSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLTT-----------LTIIIALTMKLGMTPFHFWIPEVT 119
Cdd:PRK06277 147 EAYKAALKYMILGNVAGSILLLGIGFLLASTGTLNITDIHNALLVnptspviygglLLLIFGLLYGSGLPPFHTIKSDIY 226

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 120 QGVTLTAGMLLLTWQKLAPISIMLQIY---------PSMNTnILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWM 190
Cdd:PRK06277 227 AKAKPFGSALLQTFSKFVLVALMLVIFklfgglsyfPSAQG-VLIALSVLAMVFGVVMALLQTDYKRLLAYHAISQGGYV 305

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 191 VAVLTFCPSLTI-------LNLLIYL-MLTITLFTMLNVNTSTTTLTLSILWNKNPTITLMILTSLLSLGGLPPLTGFLP 262
Cdd:PRK06277 306 AAGLALGTPLGIvagifhaINHVIYKsALFLGAGIVSYRTKTSNLRKLGGLLPVMPVVAFMVLCAKLAISGVPPFNGFQS 385

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 745999820 263 KWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKWQLQPTKFTLF 325
Cdd:PRK06277 386 KLMLAQAAMQANMPELAIIMIIVSIGTFVSMMKAFYLIYLKPKPEELEYKNKKVPKYAVFSLA 448
PRK08676 PRK08676
hydrogenase membrane subunit; Validated
 17-210 2.21e-04

hydrogenase membrane subunit; Validated


Pssm-ID: 181537 [Multi-domain]  Cd Length: 485  Bit Score: 42.82  E-value: 2.21e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  17 TMLTMISSHWLLIWMGLEMNML---AIIPILAKKTNprsTEAATKYFLTQATA------SMLLMMTIVINAMYTGQWNVT 87
Cdd:PRK08676 115 ITFAFFSDNLALFWIFAELTTVfsaMLIAILSAREN---IDAALKYIFIASTAmifafiGLIFLFSLTRQALGTGTLNWT 191

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  88 NIHNL----------LTTLTIIIALTMKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLTwqKLAPISIMLQIY 146
Cdd:PRK08676 192 ELAAHasllspsvlgASFLFIFIGFLAKSGLVPFHTWLPAayakapsvvsaLLSGTVLNIGIYGIL--RLSALLRQSGAA 269

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 745999820 147 PSMnTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYLM 210
Cdd:PRK08676 270 EQF-SNVLIGLGIFSIAVAAFSMLSQRNLKKLIAFSSIEHMGLMLLGIGIGTPLALFWMLFHML 332
ND4 MTH00217
NADH dehydrogenase subunit 4; Provisional
 96-211 5.59e-04

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214462 [Multi-domain]  Cd Length: 482  Bit Score: 41.58  E-value: 5.59e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  96 LTIIIALTMKLGMTPFHFWIPEV-----TQGVTLTAGMLLltwqKLAP---ISIMLQIYPSMN---TNILLTFALLSALV 164
Cdd:MTH00217 210 LGFFLSLAIKIPKIPFHIWLPQAhveapVAGSVILAGVLL----KLGGygfIRFSWPLLPEASeyfSPLIQTLSLLAIIY 285

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....*..
gi 745999820 165 GGWGGLNQTQLRKILAYSSIAHMGwMVAVLTFCPSLTILNLLIYLML 211
Cdd:MTH00217 286 GSLTTCRQVDLKRIIAYSSVAHMG-LVTLGIFSHTIQGLVAAIFLML 331
PRK12667 PRK12667
putative monovalent cation/H+ antiporter subunit D; Reviewed
 99-299 7.14e-04

putative monovalent cation/H+ antiporter subunit D; Reviewed


Pssm-ID: 237167 [Multi-domain]  Cd Length: 520  Bit Score: 41.50  E-value: 7.14e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  99 IIALTMKLGMTPFHFWIPE-----------------VTQGVTLTAGMLLLTWQklapISIMLQIYPSMNTNILLTFALLS 161
Cdd:PRK12667 230 LWAFTIKAAIFPNHFWLPDahpaapspvsamlsglvVNVGAYAIIRFLYTIFG----ISPSLIDFRAALSPILIILGAVS 305

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 162 ALVGGWGGLNQTQLRKILAYSSIAHMGWMVAVLTFCPSLTILNLLIYL--------MLTITLFTMLNVNTSTTTLTLSIL 233
Cdd:PRK12667 306 AIIGALMMVVQKDVKRLLAYSTISHMGYIFMGIGIGTQLGLAAALFHIinhaiaksLLFLASGVFIHAAGTRDIDELAGL 385

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 745999820 234 WNKNPTITLMILTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYS 299
Cdd:PRK12667 386 GRKMPIASFAFLIGALSLVGIPPLNGFFSKLLLFNALLESGFYLPALVLLIASAISLVGYFRAWYS 451
ndhB CHL00049
NADH dehydrogenase subunit 2
 47-297 1.91e-03

NADH dehydrogenase subunit 2


Pssm-ID: 176990 [Multi-domain]  Cd Length: 494  Bit Score: 39.99  E-value: 1.91e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  47 KTNPRSTEAATKYFLTQATASMLL----------------MMTIVINAMYTGQWNVTNIhnLLTTLTIIIALTMKLGMTP 110
Cdd:CHL00049 155 KKDVRSNEATMKYLLMGGASSSILvygfswlyglsggeieLQEIVNGLINTQMYNSPGI--SIALIFITVGIGFKLSLAP 232

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 111 FHFWIPEVTQG----------VTLTAGMLLLTwqklapISIMLQIYPSMNT---NILLTFALLSALVGGWGGLNQTQLRK 177
Cdd:CHL00049 233 FHQWTPDVYEGsptpvvaflsVTSKVAASALA------TRIFDIPFYFSSNewhLLLEILAILSMILGNLIAITQTSMKR 306

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 178 ILAYSSIAHMGW-MVAVLTFCPSLTILNLLIYLMLTItlftMLNVNTSTTTLTLSI------------LWNKNPTITLMI 244
Cdd:CHL00049 307 MLAYSSIGQIGYvIIGIIVGDSNDGYASMITYMLFYI----FMNLGTFACIVLFGLrtgtdnirdyagLYTKDPFLALSL 382

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|...
gi 745999820 245 LTSLLSLGGLPPLTGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLI 297
Cdd:CHL00049 383 ALCLLSLGGIPPLAGFFGKLYLFWCGWQAGLYFLVSIGLLTSVISIYYYLKII 435
PRK07363 PRK07363
NADH-quinone oxidoreductase subunit M;
85-191 3.00e-03

NADH-quinone oxidoreductase subunit M;


Pssm-ID: 180945 [Multi-domain]  Cd Length: 501  Bit Score: 39.31  E-value: 3.00e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  85 NVTNIHNLLTTLTIIIALTMKLGMTPFHFWIP----EVTQGVTLTAGMLLLTWQKLAPISIMLQIYP---SMNTNILLTF 157
Cdd:PRK07363 198 NLSLNTQLILLTGLLLGFGIKIPLVPLHTWLPdaytEASPAVAILLGGVLAKLGTYGLLRFGLQLFPqtwSLVAPGLAII 277

                         90       100       110
                 ....*....|....*....|....*....|....
gi 745999820 158 ALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMV 191
Cdd:PRK07363 278 GTISVIYGALSAIAQKDIKRMVAYSSIGHMGYIL 311
PRK12668 PRK12668
Na(+)/H(+) antiporter subunit D;
50-192 3.78e-03

Na(+)/H(+) antiporter subunit D;


Pssm-ID: 237168 [Multi-domain]  Cd Length: 581  Bit Score: 39.11  E-value: 3.78e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  50 PRSTEAATKYFLTQATASMLLMMTIVINAMYTGQWNVTNIHNLLTTLTIIIALTM--KLGMTPFHFWIPE------VTQG 121
Cdd:PRK12668 139 KAAVRAGFRYLLVHVLGGVLLLAGILLHYAETGSFAFGAIAGLGGTAAWLILIGFgvNAAFPPLHAWLPDaypeatVTGS 218

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 122 VTLTA---------------GMLLLTWqklapISIMLQIYPsmntnilLTFALLsalvggwgglnQTQLRKILAYSSIAH 186
Cdd:PRK12668 219 VFLSAfttktavyalarafpGTELLIY-----IGAAMAVYG-------VFFALL-----------ENDLRRLLSYHIVSQ 275


                 ....*.
gi 745999820 187 MGWMVA 192
Cdd:PRK12668 276 VGYMVA 281
PRK06458 PRK06458
hydrogenase 4 subunit F; Validated
 13-191 3.98e-03

hydrogenase 4 subunit F; Validated


Pssm-ID: 235805 [Multi-domain]  Cd Length: 490  Bit Score: 38.76  E-value: 3.98e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  13 IFTGTML-TMISSHWLLIWMGLEMNMLAIIPILAKKTNPRSTEAATKYFL------TQATASMLLMM----TIVINAMYT 81
Cdd:PRK06458 116 LFLFTMLlALTSNNLGLMWVAIEATTLSSALLVGIYRTRASLEAAWKYIIicsvgvAFALFGTILVYanaaTVMGDGEMA 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  82 GQWNVTNIHN-----LLTTLTIIIALT---MKLGMTPFHFWIPE-----------VTQGVTLTAGMLLLTWQKlapISIM 142
Cdd:PRK06458 196 ILWTELLKHAslldpTLMKLAFVFLLIgfgTKVGLFPMHAWLPDahseapspvsaLLSGVLLNVALYAVLRYY---ILID 272

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*....
gi 745999820 143 LQIYPSMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIAHMGWMV 191
Cdd:PRK06458 273 AAIGSDFPGRLLLIFGLLSVLVAAFFLLRQRDIKRLFAYSSIEHMGLIA 321
ND5 MTH00032
NADH dehydrogenase subunit 5; Provisional
 111-194 6.31e-03

NADH dehydrogenase subunit 5; Provisional


Pssm-ID: 214407 [Multi-domain]  Cd Length: 669  Bit Score: 38.40  E-value: 6.31e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 111 FHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYP-----SMNTNILLTFALLSALVGGWGGLNQTQLRKILAYSSIA 185
Cdd:MTH00032 244 LHTWLPDAMEGPTPVSALIHAATMVTAGVFLMIRSFPlfekaPLTLLIITIFGALTAFFAATVGLVQNDLKKVIAYSTCS 323


                 ....*....
gi 745999820 186 HMGWMVAVL 194
Cdd:MTH00032 324 QLGYMVLII 332
ND2 MTH00091
NADH dehydrogenase subunit 2; Provisional
 98-315 7.33e-03

NADH dehydrogenase subunit 2; Provisional


Pssm-ID: 177154  Cd Length: 273  Bit Score: 37.54  E-value: 7.33e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  98 IIIALTMKLGMTPFHFWIPEVTQGVTLTAGMLLLTWQKLAPISIMLQIYPSMNTNILLTFALLSALVggwgGLNQTQLRK 177
Cdd:MTH00091  63 QFLILMMKIGVAPFHFWIFSVTNGLFGWNLMWFLTFQKLPFLLVLLQFFSKNFFFLLLFGLLICFFQ----MFLLKSYKN 138

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820 178 ILAYSSIAHMGWMVAVLTFCpslTILNLLIYLMLTITLFTMLNvntstttltlsiLWNKNPTITLMILTSLLSLGGLPPL 257
Cdd:MTH00091 139 LLILSSTESFNWLILSFFFS---FFNVFFLFFYYFLLMLFLIP------------KFNNVNKLNFVSWETLLVFMNLPFS 203

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 745999820 258 TGFLPKWVIVQELTKNNNITMATIMVITALLNLYFYMRLIYSTSLTMFPTSNNMKMKW 315
Cdd:MTH00091 204 VTFFVKIFSLSEILKVLGFFLLFLLFLMFLSVLSLSFWLVNLSTKLFLMLFKYNKGFF 261
ND4 MTH00226
NADH dehydrogenase subunit 4; Provisional
 96-211 7.44e-03

NADH dehydrogenase subunit 4; Provisional


Pssm-ID: 214466 [Multi-domain]  Cd Length: 505  Bit Score: 37.98  E-value: 7.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 745999820  96 LTIIIALTMKLGMTPFHFWIPEV-----TQGVTLTAGmLLLTWQKLAPISIMLQIYPSMNTNI---LLTFALLSALVGGW 167
Cdd:MTH00226 234 LGIFLAMAVKIPIFPFHIWLPKAhveapVAGSVLLAG-ILLKLGGYGLVRLSWPILPLGAQNLapaVIAMGIVGIVYGSF 312

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 745999820 168 GGLNQTQLRKILAYSSIAHMGwMVAVLTFCPSLTILNLLIYLML 211
Cdd:MTH00226 313 ATCRQIDVKRLVAYSSVAHMG-LVSITLVTHDIIGLTGSIFIML 355
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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