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Conserved domains on  [gi|74355480|gb|AAI03926|]
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UDP glycosyltransferase 3 family, polypeptide A2 [Homo sapiens]

Protein Classification

glycosyltransferase family protein( domain architecture ID 56)

glycosyltransferase family protein may synthesize oligosaccharides, polysaccharides, and glycoconjugates by transferring the sugar moiety from an activated nucleotide-sugar donor to an acceptor molecule, which may be a growing oligosaccharide, a lipid, or a protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Glycosyltransferase_GTB-type super family cl10013
glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases ...
 23-491 1.67e-95

glycosyltransferase family 1 and related proteins with GTB topology; Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


The actual alignment was detected with superfamily member pfam00201:

Pssm-ID: 471961 [Multi-domain]  Cd Length: 499  Bit Score: 298.94  E-value: 1.67e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    23 AKILTISTvGGSHYLLMDRVSQILQDHGHNVTML----NHKRGPFMPDFKKEEkSYQViSWLApEDHQREFKKSFDFFLE 98
Cdd:pfam00201   1 GKVLVWPM-DGSHWMNMKGILEELVQRGHEVTVLrpsaSISIGPGKPSNLKFE-TYPT-SATK-EELENPFPKRQMQWFE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    99 ETLGGRGK--FENLLNVLEYLALQCSHFLNRKDIMDSLKNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEF- 175
Cdd:pfam00201  77 EASFGTVWsyFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEk 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   176 ---GLPIPLSYVPVFRSLLTDHMDFWGRVKNFLMFFSFCRRQQHMQSTFDNTIKEHFTegsRPV-LSHLLLKAELWFINS 251
Cdd:pfam00201 157 vsgGLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLG---RPVtLPELMSKASVWLIRS 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   252 DFAFDFARPLLPNTVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVntCQNPE-IFKEMNNAFAHLPQGVIWK 330
Cdd:pfam00201 234 YWDLEFPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMV--SNIPEeKANAIASALAQIPQKVLWR 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   331 CQCShwpKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSI 410
Cdd:pfam00201 312 FDGT---KPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTL 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   411 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLLDVFV 490
Cdd:pfam00201 389 NVLTMTSEDLLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIG 468


                  .
gi 74355480   491 F 491
Cdd:pfam00201 469 F 469
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
23-491 1.67e-95

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 298.94  E-value: 1.67e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    23 AKILTISTvGGSHYLLMDRVSQILQDHGHNVTML----NHKRGPFMPDFKKEEkSYQViSWLApEDHQREFKKSFDFFLE 98
Cdd:pfam00201   1 GKVLVWPM-DGSHWMNMKGILEELVQRGHEVTVLrpsaSISIGPGKPSNLKFE-TYPT-SATK-EELENPFPKRQMQWFE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    99 ETLGGRGK--FENLLNVLEYLALQCSHFLNRKDIMDSLKNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEF- 175
Cdd:pfam00201  77 EASFGTVWsyFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEk 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   176 ---GLPIPLSYVPVFRSLLTDHMDFWGRVKNFLMFFSFCRRQQHMQSTFDNTIKEHFTegsRPV-LSHLLLKAELWFINS 251
Cdd:pfam00201 157 vsgGLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLG---RPVtLPELMSKASVWLIRS 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   252 DFAFDFARPLLPNTVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVntCQNPE-IFKEMNNAFAHLPQGVIWK 330
Cdd:pfam00201 234 YWDLEFPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMV--SNIPEeKANAIASALAQIPQKVLWR 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   331 CQCShwpKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSI 410
Cdd:pfam00201 312 FDGT---KPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTL 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   411 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLLDVFV 490
Cdd:pfam00201 389 NVLTMTSEDLLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIG 468


                  .
gi 74355480   491 F 491
Cdd:pfam00201 469 F 469
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 23-445 8.67e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 244.77  E-value: 8.67e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  23 AKILTISTVGGSHYLLMDRVSQILQDHGHNVTMLNHKrgpfmpdfkkeeksyqviswLAPEDHQREFKKSFDFFLEETLG 102
Cdd:cd03784   1 MRILFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP--------------------FNFADLVEAAGLTFVPVGDDPDE 60

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 103 GRGKFENLLNVLEYLALQCSHFLNRKDIMDSL-----KNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEFGL 177
Cdd:cd03784  61 LELDSETNLGPDSLLELLRRLLKAADELLDDLlaalrSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 178 PiplsYVPVFRSLLTDHMDFWGRVKNFLMFFSFcRRQQHMQSTFdntikehftegSRPVLSHLLLKAELWFINSDFAFDF 257
Cdd:cd03784 141 H----PFGVLNLLLSSLLEPELFLDPLLEVLDR-LRERLGLPPF-----------SLVLLLLRLVPPLYVIGPTFPSLPP 204

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 258 ARPLLPNtVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVNtcQNPEIFKEMN-NAFAHLPQGVIWKCQCSHW 336
Cdd:cd03784 205 DRPRLPS-VLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVR--DLPEELLELIaEALASLGQRFLWVVGPDPL 281

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 337 PKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLK 416
Cdd:cd03784 282 GGLERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELT 361

                       410       420
                ....*....|....*....|....*....
gi 74355480 417 AETLALKMKQIMEDKRYKSAAVAASVILR 445
Cdd:cd03784 362 AEELAKAVREVLEDESYRRAAELLAELRE 390
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 135-490 6.79e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 159.74  E-value: 6.79e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  135 KNENFDMVIVETF-DYcpfliaeklgkPFVailstsFGSLEFGLPI----------------------PLSYVPVFRSLL 191
Cdd:PHA03392 133 KNNKFDLLVTEAFlDY-----------PLV------FSHLFGDAPViqissgyglaenfetmgavsrhPVYYPNLWRSKF 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  192 TDhMDFWGRVKNFLM-------FFSFCRRQqhmqstfDNTIKEHFTEGSrPVLSHLLLKAELWFINSDFAFDFARPLLPN 264
Cdd:PHA03392 196 GN-LNVWETINEIYTelrlyneFSLLADEQ-------NKLLKQQFGPDT-PTIRELRNRVQLLFVNVHPVFDNNRPVPPS 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  265 TVYVGG--LMEKPIKPVPQDLENFIAKfGDSGFVLVTLGSMVNTCQ-NPEIFKEMNNAFAHLPQGVIWKCQCSHwpKDVH 341
Cdd:PHA03392 267 VQYLGGlhLHKKPPQPLDDYLEEFLNN-STNGVVYVSFGSSIDTNDmDNEFLQMLLRTFKKLPYNVLWKYDGEV--EAIN 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  342 LAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLA 421
Cdd:PHA03392 344 LPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLV 423

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  422 LKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVL-QTGGATHLKPYVFQQPWHEQYLLDVFV 490
Cdd:PHA03392 424 LAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIrNKHGNTSLKTKAANVSYSDYFMSYILV 493
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
254-445 1.99e-36

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 136.14  E-value: 1.99e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 254 AFDFARPLLP-NTVYVGGLmekpIKPVPQDLENFIAKFGDSGFVLVTLGSMVNtcQNPEIFKEMNNAFAHLP-QGVIwkC 331
Cdd:COG1819  84 ELEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAN--DRADLLRAVLEALADLGvRVVV--T 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 332 QCSHWPKDV-HLAANVKIVDWLPQSDLLAHpsIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSI 410
Cdd:COG1819 156 TGGLDPAELgPLPDNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLAL 233

                       170       180       190
                ....*....|....*....|....*....|....*
gi 74355480 411 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILR 445
Cdd:COG1819 234 PPRRLTAEALRAALRRLLADPSYRERAARLAAEIR 268
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 296-436 9.05e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 91.28  E-value: 9.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   296 VLVTLGSMVNtcQNPEIFKEMNNAFAHLPQGVIWKCQCSHWPKDV-HLAANVKIVDWLPQSDLLAHPSirLFVTHGGQNS 374
Cdd:TIGR01426 228 VLISLGTVFN--NQPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLgELPPNVEVRQWVPQLEILKKAD--AFITHGGMNS 303

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74355480   375 IMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYKSA 436
Cdd:TIGR01426 304 TMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAER 365
 
Name Accession Description Interval E-value
UDPGT pfam00201
UDP-glucoronosyl and UDP-glucosyl transferase;
23-491 1.67e-95

UDP-glucoronosyl and UDP-glucosyl transferase;


Pssm-ID: 278624 [Multi-domain]  Cd Length: 499  Bit Score: 298.94  E-value: 1.67e-95
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    23 AKILTISTvGGSHYLLMDRVSQILQDHGHNVTML----NHKRGPFMPDFKKEEkSYQViSWLApEDHQREFKKSFDFFLE 98
Cdd:pfam00201   1 GKVLVWPM-DGSHWMNMKGILEELVQRGHEVTVLrpsaSISIGPGKPSNLKFE-TYPT-SATK-EELENPFPKRQMQWFE 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480    99 ETLGGRGK--FENLLNVLEYLALQCSHFLNRKDIMDSLKNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEF- 175
Cdd:pfam00201  77 EASFGTVWsyFSALQEYSDGYRVTCKELVGNKKLMTKLQESSFDVVLADPVWPCGELLAELLHIPTVYSLRFVPGYAAEk 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   176 ---GLPIPLSYVPVFRSLLTDHMDFWGRVKNFLMFFSFCRRQQHMQSTFDNTIKEHFTegsRPV-LSHLLLKAELWFINS 251
Cdd:pfam00201 157 vsgGLPSPPSYVPVILSDLSDHMTFMERVKNMLIMLYFDFWFQCFPRKWDQFASEVLG---RPVtLPELMSKASVWLIRS 233

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   252 DFAFDFARPLLPNTVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVntCQNPE-IFKEMNNAFAHLPQGVIWK 330
Cdd:pfam00201 234 YWDLEFPRPLLPNMDFIGGLHCKPAKPLPQEMEAFVQSSGEHGVVVFSLGSMV--SNIPEeKANAIASALAQIPQKVLWR 311

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   331 CQCShwpKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSI 410
Cdd:pfam00201 312 FDGT---KPSTLGNNTRLVKWLPQNDLLGHPKTRAFITHAGSNGVYEAICHGVPMVGMPLFGDQMDNAKHMEAKGAAVTL 388

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   411 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVLQTGGATHLKPYVFQQPWHEQYLLDVFV 490
Cdd:pfam00201 389 NVLTMTSEDLLNALKEVINDPSYKENIMRLSSIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRPAAHDLTWYQYHSLDVIG 468


                  .
gi 74355480   491 F 491
Cdd:pfam00201 469 F 469
GT1_Gtf-like cd03784
UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of ...
 23-445 8.67e-76

UDP-glycosyltransferases and similar proteins; This family includes the Gtfs, a group of homologous glycosyltransferases involved in the final stages of the biosynthesis of antibiotics vancomycin and related chloroeremomycin. Gtfs transfer sugar moieties from an activated NDP-sugar donor to the oxidatively cross-linked heptapeptide core of vancomycin group antibiotics. The core structure is important for the bioactivity of the antibiotics.


Pssm-ID: 340817 [Multi-domain]  Cd Length: 404  Bit Score: 244.77  E-value: 8.67e-76
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  23 AKILTISTVGGSHYLLMDRVSQILQDHGHNVTMLNHKrgpfmpdfkkeeksyqviswLAPEDHQREFKKSFDFFLEETLG 102
Cdd:cd03784   1 MRILFVPFPGQGHVNPMLPLAKALAARGHEVTVATPP--------------------FNFADLVEAAGLTFVPVGDDPDE 60

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 103 GRGKFENLLNVLEYLALQCSHFLNRKDIMDSL-----KNENFDMVIVETFDYCPFLIAEKLGKPFVAILSTSFGSLEFGL 177
Cdd:cd03784  61 LELDSETNLGPDSLLELLRRLLKAADELLDDLlaalrSSWKPDLVIADPFAYAGPLVAEELGIPSVRLFTGPATLLSAYL 140

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 178 PiplsYVPVFRSLLTDHMDFWGRVKNFLMFFSFcRRQQHMQSTFdntikehftegSRPVLSHLLLKAELWFINSDFAFDF 257
Cdd:cd03784 141 H----PFGVLNLLLSSLLEPELFLDPLLEVLDR-LRERLGLPPF-----------SLVLLLLRLVPPLYVIGPTFPSLPP 204

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 258 ARPLLPNtVYVGGLMEKPIKPVPQDLENFIAKFGDSGFVLVTLGSMVNtcQNPEIFKEMN-NAFAHLPQGVIWKCQCSHW 336
Cdd:cd03784 205 DRPRLPS-VLGGLRIVPKNGPLPDELWEWLDKQPPRSVVYVSFGSMVR--DLPEELLELIaEALASLGQRFLWVVGPDPL 281

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 337 PKDVHLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLK 416
Cdd:cd03784 282 GGLERLPDNVLVVKWVPQDELLAHPAVGAFVTHGGWNSTLEALYAGVPMVVVPLFADQPNNAARVEELGAGVELDKDELT 361

                       410       420
                ....*....|....*....|....*....
gi 74355480 417 AETLALKMKQIMEDKRYKSAAVAASVILR 445
Cdd:cd03784 362 AEELAKAVREVLEDESYRRAAELLAELRE 390
egt PHA03392
ecdysteroid UDP-glucosyltransferase; Provisional
 135-490 6.79e-43

ecdysteroid UDP-glucosyltransferase; Provisional


Pssm-ID: 223071 [Multi-domain]  Cd Length: 507  Bit Score: 159.74  E-value: 6.79e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  135 KNENFDMVIVETF-DYcpfliaeklgkPFVailstsFGSLEFGLPI----------------------PLSYVPVFRSLL 191
Cdd:PHA03392 133 KNNKFDLLVTEAFlDY-----------PLV------FSHLFGDAPViqissgyglaenfetmgavsrhPVYYPNLWRSKF 195

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  192 TDhMDFWGRVKNFLM-------FFSFCRRQqhmqstfDNTIKEHFTEGSrPVLSHLLLKAELWFINSDFAFDFARPLLPN 264
Cdd:PHA03392 196 GN-LNVWETINEIYTelrlyneFSLLADEQ-------NKLLKQQFGPDT-PTIRELRNRVQLLFVNVHPVFDNNRPVPPS 266

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  265 TVYVGG--LMEKPIKPVPQDLENFIAKfGDSGFVLVTLGSMVNTCQ-NPEIFKEMNNAFAHLPQGVIWKCQCSHwpKDVH 341
Cdd:PHA03392 267 VQYLGGlhLHKKPPQPLDDYLEEFLNN-STNGVVYVSFGSSIDTNDmDNEFLQMLLRTFKKLPYNVLWKYDGEV--EAIN 343

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  342 LAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLA 421
Cdd:PHA03392 344 LPANVLTQKWFPQRAVLKHKNVKAFVTQGGVQSTDEAIDALVPMVGLPMMGDQFYNTNKYVELGIGRALDTVTVSAAQLV 423

                        330       340       350       360       370       380       390
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  422 LKMKQIMEDKRYKSAAVAASVILRSHPLSPTQRLVGWIDHVL-QTGGATHLKPYVFQQPWHEQYLLDVFV 490
Cdd:PHA03392 424 LAIVDVIENPKYRKNLKELRHLIRHQPMTPLHKAIWYTEHVIrNKHGNTSLKTKAANVSYSDYFMSYILV 493
YjiC COG1819
UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];
254-445 1.99e-36

UDP:flavonoid glycosyltransferase YjiC, YdhE family [Carbohydrate transport and metabolism];


Pssm-ID: 441424 [Multi-domain]  Cd Length: 268  Bit Score: 136.14  E-value: 1.99e-36
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 254 AFDFARPLLP-NTVYVGGLmekpIKPVPQDLENFIAKFGDSGFVLVTLGSMVNtcQNPEIFKEMNNAFAHLP-QGVIwkC 331
Cdd:COG1819  84 ELEYPRPPDPaNVRFVGPL----LPDGPAELPPWLEEDAGRPLVYVTLGTSAN--DRADLLRAVLEALADLGvRVVV--T 155

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 332 QCSHWPKDV-HLAANVKIVDWLPQSDLLAHpsIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSI 410
Cdd:COG1819 156 TGGLDPAELgPLPDNVRVVDYVPQDALLPR--ADAVVHHGGAGTTAEALRAGVPQVVVPFGGDQPLNAARVERLGAGLAL 233

                       170       180       190
                ....*....|....*....|....*....|....*
gi 74355480 411 QLKKLKAETLALKMKQIMEDKRYKSAAVAASVILR 445
Cdd:COG1819 234 PPRRLTAEALRAALRRLLADPSYRERAARLAAEIR 268
MGT TIGR01426
glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) ...
 296-436 9.05e-20

glycosyltransferase, MGT family; This model describes the MGT (macroside glycosyltransferase) subfamily of the UDP-glucuronosyltransferase family. Members include a number of glucosyl transferases for macrolide antibiotic inactivation, but also include transferases of glucose-related sugars for macrolide antibiotic production. [Cellular processes, Toxin production and resistance]


Pssm-ID: 273616 [Multi-domain]  Cd Length: 392  Bit Score: 91.28  E-value: 9.05e-20
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   296 VLVTLGSMVNtcQNPEIFKEMNNAFAHLPQGVIWKCQCSHWPKDV-HLAANVKIVDWLPQSDLLAHPSirLFVTHGGQNS 374
Cdd:TIGR01426 228 VLISLGTVFN--NQPSFYRTCVEAFRDLDWHVVLSVGRGVDPADLgELPPNVEVRQWVPQLEILKKAD--AFITHGGMNS 303

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 74355480   375 IMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYKSA 436
Cdd:TIGR01426 304 TMEALFNGVPMVAVPQGADQPMTARRIAELGLGRHLPPEEVTAEKLREAVLAVLSDPRYAER 365
PLN00164 PLN00164
glucosyltransferase; Provisional
 351-413 3.23e-14

glucosyltransferase; Provisional


Pssm-ID: 215084 [Multi-domain]  Cd Length: 480  Bit Score: 74.71  E-value: 3.23e-14
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 74355480  351 WLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEN---MVRVeakkFGVSIQLK 413
Cdd:PLN00164 346 WAPQKEILAHAAVGGFVTHCGWNSVLESLWHGVPMAPWPLYAEQHLNafeLVAD----MGVAVAMK 407
PLN02555 PLN02555
limonoid glucosyltransferase
 347-440 1.51e-13

limonoid glucosyltransferase


Pssm-ID: 178170 [Multi-domain]  Cd Length: 480  Bit Score: 72.91  E-value: 1.51e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  347 KIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVR-VEAKKFGVSIQ-------------- 411
Cdd:PLN02555 340 KIVQWCPQEKVLAHPSVACFVTHCGWNSTMEALSSGVPVVCFPQWGDQVTDAVYlVDVFKTGVRLCrgeaenklitreev 419

                         90       100       110
                 ....*....|....*....|....*....|
gi 74355480  412 LKKLKAETLALKMKQIMED-KRYKSAAVAA 440
Cdd:PLN02555 420 AECLLEATVGEKAAELKQNaLKWKEEAEAA 449
PLN02173 PLN02173
UDP-glucosyl transferase family protein
 348-434 5.21e-13

UDP-glucosyl transferase family protein


Pssm-ID: 177830 [Multi-domain]  Cd Length: 449  Bit Score: 70.83  E-value: 5.21e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVE-AKKFGVSIQLKK----LKAETLAL 422
Cdd:PLN02173 321 VLKWSPQLQVLSNKAIGCFMTHCGWNSTMEGLSLGVPMVAMPQWTDQPMNAKYIQdVWKVGVRVKAEKesgiAKREEIEF 400

                         90
                 ....*....|..
gi 74355480  423 KMKQIMEDKRYK 434
Cdd:PLN02173 401 SIKEVMEGEKSK 412
PLN02554 PLN02554
UDP-glycosyltransferase family protein
 347-430 6.45e-12

UDP-glycosyltransferase family protein


Pssm-ID: 215304  Cd Length: 481  Bit Score: 67.50  E-value: 6.45e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  347 KIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEN---MVrveaKKFGVSIQLKK-LKAETLAL 422
Cdd:PLN02554 345 KVIGWAPQVAVLAKPAIGGFVTHCGWNSILESLWFGVPMAAWPLYAEQKFNafeMV----EELGLAVEIRKyWRGDLLAG 420


                 ....*...
gi 74355480  423 KMKQIMED 430
Cdd:PLN02554 421 EMETVTAE 428
PLN02210 PLN02210
UDP-glucosyl transferase
 293-413 2.69e-11

UDP-glucosyl transferase


Pssm-ID: 215127 [Multi-domain]  Cd Length: 456  Bit Score: 65.83  E-value: 2.69e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  293 SGFVLVTLGSMVNTCQN--PEIFKEMNNafahlpQGV--IWKCQCSHWPKDVH-LAANVK-----IVDWLPQSDLLAHPS 362
Cdd:PLN02210 269 SSVVYISFGSMLESLENqvETIAKALKN------RGVpfLWVIRPKEKAQNVQvLQEMVKegqgvVLEWSPQEKILSHMA 342

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 74355480  363 IRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENmVRVEAKKFGVSIQLK 413
Cdd:PLN02210 343 ISCFVTHCGWNSTIETVVAGVPVVAYPSWTDQPID-ARLLVDVFGIGVRMR 392
PLN02992 PLN02992
coniferyl-alcohol glucosyltransferase
 348-431 2.19e-10

coniferyl-alcohol glucosyltransferase


Pssm-ID: 178572 [Multi-domain]  Cd Length: 481  Bit Score: 62.69  E-value: 2.19e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVeAKKFGVSIQLKKLK-----AETLAL 422
Cdd:PLN02992 342 VPSWAPQAEILAHQAVGGFLTHCGWSSTLESVVGGVPMIAWPLFAEQNMNAALL-SDELGIAVRSDDPKevisrSKIEAL 420


                 ....*....
gi 74355480  423 KMKQIMEDK 431
Cdd:PLN02992 421 VRKVMVEEE 429
PLN02207 PLN02207
UDP-glycosyltransferase
 97-412 3.59e-10

UDP-glycosyltransferase


Pssm-ID: 177857 [Multi-domain]  Cd Length: 468  Bit Score: 61.98  E-value: 3.59e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   97 LEE--TLGGRGKFENLLnvleYLALQCSHFLNRKDIMDSLKNENFDMVIVETFD---YC-PFL-IAEKLGKPFVAILSTS 169
Cdd:PLN02207  71 LEEkpTLGGTQSVEAYV----YDVIEKNIPLVRNIVMDILSSLALDGVKVKGFVadfFClPMIdVAKDVSLPFYVFLTTN 146

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  170 FGSLEFglpipLSYVPVFRSLLTDhmdfwgrvknflmffSFCRRQQHMQST--FDNTIKEH------FTEGSRPV---LS 238
Cdd:PLN02207 147 SGFLAM-----MQYLADRHSKDTS---------------VFVRNSEEMLSIpgFVNPVPANvlpsalFVEDGYDAyvkLA 206

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  239 HLLLKAELWFINSDFAFD-------FARPLLPNTVYVGGLMEKPIKPVP-QDLE------NFIAKFGDSGFVLVTLGSMv 304
Cdd:PLN02207 207 ILFTKANGILVNSSFDIEpysvnhfLDEQNYPSVYAVGPIFDLKAQPHPeQDLArrdelmKWLDDQPEASVVFLCFGSM- 285

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  305 NTCQNPeIFKEMNNAFAHLPQGVIWKCQCSHWPKDV--------HLAANVKIVDWLPQSDLLAHPSIRLFVTHGGQNSIM 376
Cdd:PLN02207 286 GRLRGP-LVKEIAHGLELCQYRFLWSLRTEEVTNDDllpegfldRVSGRGMICGWSPQVEILAHKAVGGFVSHCGWNSIV 364

                        330       340       350
                 ....*....|....*....|....*....|....*..
gi 74355480  377 EAIQHGVPMVGIPLFGDQPEN-MVRVEAKKFGVSIQL 412
Cdd:PLN02207 365 ESLWFGVPIVTWPMYAEQQLNaFLMVKELKLAVELKL 401
PLN02448 PLN02448
UDP-glycosyltransferase family protein
 348-420 5.78e-10

UDP-glycosyltransferase family protein


Pssm-ID: 215247 [Multi-domain]  Cd Length: 459  Bit Score: 61.56  E-value: 5.78e-10
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEN--MVrVEAKKFGVSIQlKKLKAETL 420
Cdd:PLN02448 327 VVPWCDQLKVLCHSSVGGFWTHCGWNSTLEAVFAGVPMLTFPLFWDQPLNskLI-VEDWKIGWRVK-REVGEETL 399
PLN02410 PLN02410
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 348-411 1.67e-09

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 178032 [Multi-domain]  Cd Length: 451  Bit Score: 60.05  E-value: 1.67e-09
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAK-KFGVSIQ 411
Cdd:PLN02410 328 IVKWAPQKEVLSHPAVGGFWSHCGWNSTLESIGEGVPMICKPFSSDQKVNARYLECVwKIGIQVE 392
PLN03015 PLN03015
UDP-glucosyl transferase
 348-441 3.71e-09

UDP-glucosyl transferase


Pssm-ID: 178589 [Multi-domain]  Cd Length: 470  Bit Score: 58.94  E-value: 3.71e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVeAKKFGVSIQLKKLKA------ETLA 421
Cdd:PLN03015 339 VTQWAPQVEILSHRSIGGFLSHCGWSSVLESLTKGVPIVAWPLYAEQWMNATLL-TEEIGVAVRTSELPSekvigrEEVA 417

                         90       100
                 ....*....|....*....|....*..
gi 74355480  422 LKMKQIM--EDK-----RYKSAAVAAS 441
Cdd:PLN03015 418 SLVRKIVaeEDEegqkiRAKAEEVRVS 444
PLN02152 PLN02152
indole-3-acetate beta-glucosyltransferase
 348-431 5.28e-09

indole-3-acetate beta-glucosyltransferase


Pssm-ID: 177813 [Multi-domain]  Cd Length: 455  Bit Score: 58.53  E-value: 5.28e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAK-KFGVSIQLKK---LKAETLALK 423
Cdd:PLN02152 331 IVSWCSQIEVLRHRAVGCFVTHCGWSSSLESLVLGVPVVAFPMWSDQPANAKLLEEIwKTGVRVRENSeglVERGEIRRC 410


                 ....*...
gi 74355480  424 MKQIMEDK 431
Cdd:PLN02152 411 LEAVMEEK 418
PLN02534 PLN02534
UDP-glycosyltransferase
 348-410 1.09e-08

UDP-glycosyltransferase


Pssm-ID: 215293 [Multi-domain]  Cd Length: 491  Bit Score: 57.56  E-value: 1.09e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQ--PENMVrVEAKKFGVSI 410
Cdd:PLN02534 348 IKGWAPQVLILSHPAIGGFLTHCGWNSTIEGICSGVPMITWPLFAEQflNEKLI-VEVLRIGVRV 411
PLN02167 PLN02167
UDP-glycosyltransferase family protein
 348-440 1.82e-08

UDP-glycosyltransferase family protein


Pssm-ID: 215112 [Multi-domain]  Cd Length: 475  Bit Score: 56.73  E-value: 1.82e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEN---MVrveaKKFGVSIQLKK---------L 415
Cdd:PLN02167 344 VCGWAPQVEILAHKAIGGFVSHCGWNSVLESLWFGVPIATWPMYAEQQLNaftMV----KELGLAVELRLdyvsaygeiV 419

                         90       100       110
                 ....*....|....*....|....*....|
gi 74355480  416 KAETLALKMKQIMED-----KRYKSAAVAA 440
Cdd:PLN02167 420 KADEIAGAVRSLMDGedvprKKVKEIAEAA 449
PLN02208 PLN02208
glycosyltransferase family protein
 351-464 3.93e-08

glycosyltransferase family protein


Pssm-ID: 177858  Cd Length: 442  Bit Score: 55.79  E-value: 3.93e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  351 WLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEnMVRVEAKKFGVSIQLKKLKA-----ETLALKMK 425
Cdd:PLN02208 318 WVQQPLILDHPSIGCFVNHCGPGTIWESLVSDCQMVLIPFLSDQVL-FTRLMTEEFEVSVEVSREKTgwfskESLSNAIK 396

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 74355480  426 QIMED-----KRYKSAAVAASVILRSHPLsptqrLVGWIDHVLQ 464
Cdd:PLN02208 397 SVMDKdsdlgKLVRSNHTKLKEILVSPGL-----LTGYVDKFVE 435
PLN03004 PLN03004
UDP-glycosyltransferase
 351-410 4.74e-08

UDP-glycosyltransferase


Pssm-ID: 178581  Cd Length: 451  Bit Score: 55.47  E-value: 4.74e-08
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74355480  351 WLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVR-VEAKKFGVSI 410
Cdd:PLN03004 341 WAPQVPVLNHKAVGGFVTHCGWNSILEAVCAGVPMVAWPLYAEQRFNRVMiVDEIKIAISM 401
PLN02562 PLN02562
UDP-glycosyltransferase
 347-431 9.61e-08

UDP-glycosyltransferase


Pssm-ID: 215305  Cd Length: 448  Bit Score: 54.50  E-value: 9.61e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  347 KIVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVR-VEAKKFGVsiQLKKLKAETLALKMK 425
Cdd:PLN02562 331 KVVSWAPQLEVLKHQAVGCYLTHCGWNSTMEAIQCQKRLLCYPVAGDQFVNCAYiVDVWKIGV--RISGFGQKEVEEGLR 408


                 ....*.
gi 74355480  426 QIMEDK 431
Cdd:PLN02562 409 KVMEDS 414
PLN02863 PLN02863
UDP-glucoronosyl/UDP-glucosyl transferase family protein
 348-394 3.25e-07

UDP-glucoronosyl/UDP-glucosyl transferase family protein


Pssm-ID: 215465  Cd Length: 477  Bit Score: 52.95  E-value: 3.25e-07
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*..
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQ 394
Cdd:PLN02863 347 IRGWAPQVAILSHRAVGAFLTHCGWNSVLEGLVAGVPMLAWPMAADQ 393
PLN03007 PLN03007
UDP-glucosyltransferase family protein
 348-415 2.92e-06

UDP-glucosyltransferase family protein


Pssm-ID: 178584 [Multi-domain]  Cd Length: 482  Bit Score: 49.86  E-value: 2.92e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 74355480  348 IVDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRV-EAKKFGVSIQLKKL 415
Cdd:PLN03007 349 IRGWAPQVLILDHQATGGFVTHCGWNSLLEGVAAGLPMVTWPVGAEQFYNEKLVtQVLRTGVSVGAKKL 417
PLN02670 PLN02670
transferase, transferring glycosyl groups
 349-442 6.33e-06

transferase, transferring glycosyl groups


Pssm-ID: 178275 [Multi-domain]  Cd Length: 472  Bit Score: 48.75  E-value: 6.33e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  349 VDWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENMVRVEAKKFGVSIQLKKlkaetlalkmkqim 428
Cdd:PLN02670 344 VGWVPQVKILSHESVGGFLTHCGWNSVVEGLGFGRVLILFPVLNEQGLNTRLLHGKKLGLEVPRDE-------------- 409

                         90
                 ....*....|....
gi 74355480  429 EDKRYKSAAVAASV 442
Cdd:PLN02670 410 RDGSFTSDSVAESV 423
PLN00414 PLN00414
glycosyltransferase family protein
 351-429 2.88e-04

glycosyltransferase family protein


Pssm-ID: 177807 [Multi-domain]  Cd Length: 446  Bit Score: 43.47  E-value: 2.88e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480  351 WLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPEnMVRVEAKKFGVSIQLKK-----LKAETLALKMK 425
Cdd:PLN00414 319 WVEQPLILSHPSVGCFVNHCGFGSMWESLVSDCQIVFIPQLADQVL-ITRLLTEELEVSVKVQRedsgwFSKESLRDTVK 397


                 ....
gi 74355480  426 QIME 429
Cdd:PLN00414 398 SVMD 401
PLN02764 PLN02764
glycosyltransferase family protein
 350-414 6.96e-04

glycosyltransferase family protein


Pssm-ID: 178364  Cd Length: 453  Bit Score: 41.97  E-value: 6.96e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 74355480  350 DWLPQSDLLAHPSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFGDQPENmVRVEAKKFGVSIQLKK 414
Cdd:PLN02764 323 GWVQQPLILSHPSVGCFVSHCGFGSMWESLLSDCQIVLVPQLGDQVLN-TRLLSDELKVSVEVAR 386
MJ1255 TIGR00661
conserved hypothetical protein; This model represents nearly the full length of MJ1255 from ...
 236-434 1.31e-03

conserved hypothetical protein; This model represents nearly the full length of MJ1255 from Methanococcus jannaschii and of an unpublished protein from Vibrio cholerae, as well as the C-terminal half of a protein from Methanobacterium thermoautotrophicum. A small region (~50 amino acids) within the domain appears related to a family of sugar transferases. [Hypothetical proteins, Conserved]


Pssm-ID: 273203  Cd Length: 321  Bit Score: 41.01  E-value: 1.31e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   236 VLSHLLLKAELWFINSdfaFDFARPLLPNTVYvggLMEKPIkpVPQDLENFIAKFGDsgFVLVTLGSMVNTCQNPEIFKE 315
Cdd:TIGR00661 141 ALRIFNERCERFIVPD---YPFPYTICPKIIK---NMEGPL--IRYDVDDVDNYGED--YILVYIGFEYRYKILELLGKI 210

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480   316 MNNAFAhlpqgviwkcqCSHW--PKDvHLAANVKIVDwLPQSDLLAH-PSIRLFVTHGGQNSIMEAIQHGVPMVGIPLFG 392
Cdd:TIGR00661 211 ANVKFV-----------CYSYevAKN-SYNENVEIRR-ITTDNFKELiKNAELVITHGGFSLISEALSLGKPLIVIPDLG 277

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*
gi 74355480   393 dQPE---NMVRVEAKKFGVSIQLKKLKAETLALKMKQImedKRYK 434
Cdd:TIGR00661 278 -QFEqgnNAVKLEDLGCGIALEYKELRLLEAILDIRNM---KRYK 318
GT28_MurG cd03785
undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4. ...
 253-440 1.49e-03

undecaprenyldiphospho-muramoylpentapeptide beta-N-acetylglucosaminyltransferase; MurG (EC 2.4.1.227) is an N-acetylglucosaminyltransferase, the last enzyme involved in the intracellular phase of peptidoglycan biosynthesis. It transfers N-acetyl-D-glucosamine (GlcNAc) from UDP-GlcNAc to the C4 hydroxyl of a lipid-linked N-acetylmuramoyl pentapeptide (NAM). The resulting disaccharide is then transported across the cell membrane, where it is polymerized into NAG-NAM cell-wall repeat structure. MurG belongs to the GT-B structural superfamily of glycoslytransferases, which have characteristic N- and C-terminal domains, each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340818 [Multi-domain]  Cd Length: 350  Bit Score: 41.05  E-value: 1.49e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 253 FAFDFARPLLPNTVYVGGLMEKPIKPVPQDLENFIAKFGDSgFVLVT---LGSMVntcqnpeIFKEMNNAFAHLP-QGVI 328
Cdd:cd03785 142 FPETKKYFPAAKVVVTGNPVREEILNLRKELKRFGLPPDKP-TLLVFggsQGARA-------INRAVPKALPKLLeRGIQ 213

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 329 WKCQC-SHWPKDV-----HLAANVKIVDWLPQ-SDLLAhpSIRLFVTHGGQNSIMEAIQHGVPMVGIPLF----GDQPEN 397
Cdd:cd03785 214 VIHQTgKGDYDEVkklyeDLGINVKVFPFIDDmAAAYA--AADLVISRAGASTIAELTAAGKPAILIPYPyaadDHQEAN 291

                       170       180       190       200
                ....*....|....*....|....*....|....*....|....
gi 74355480 398 MVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDK-RYKSAAVAA 440
Cdd:cd03785 292 ARALEKAGAAIVIDQEELTPEVLAEAILDLLNDPeRLKKMAEAA 335
Glyco_tran_28_C pfam04101
Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes ...
 365-431 4.85e-03

Glycosyltransferase family 28 C-terminal domain; The glycosyltransferase family 28 includes monogalactosyldiacylglycerol synthase (EC 2.4.1.46) and UDP-N-acetylglucosamine transferase (EC 2.4.1.-). Structural analysis suggests the C-terminal domain contains the UDP-GlcNAc binding site.


Pssm-ID: 427711 [Multi-domain]  Cd Length: 166  Bit Score: 38.08  E-value: 4.85e-03
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 74355480   365 LFVTHGGQNSIMEAIQHGVPMVGIPL----FGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDK 431
Cdd:pfam04101  74 LVISRAGAGTIAELLALGKPAILVPNpsaaRGHQDNNAKELVKAGAALVILQKELTPEKLIEALLKLLLNP 144
GT28_Beta-DGS-like cd17507
beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol ...
 356-440 8.87e-03

beta-diglucosyldiacylglycerol synthase and similar proteins; beta-diglucosyldiacylglycerol synthase (processive diacylglycerol beta-glucosyltransferase EC 2.4.1.315) is involved in the biosynthesis of both the bilayer- and non-bilayer-forming membrane glucolipids. This family of glycosyltransferases also contains plant major galactolipid synthase (chloroplastic monogalactosyldiacylglycerol synthase 1 EC 2.4.1.46). Glycosyltransferases catalyze the transfer of sugar moieties from activated donor molecules to specific acceptor molecules, forming glycosidic bonds. The acceptor molecule can be a lipid, a protein, a heterocyclic compound, or another carbohydrate residue. The structures of the formed glycoconjugates are extremely diverse, reflecting a wide range of biological functions. The members of this family share a common GTB topology, one of the two protein topologies observed for nucleotide-sugar-dependent glycosyltransferases. GTB proteins have distinct N- and C- terminal domains each containing a typical Rossmann fold. The two domains have high structural homology despite minimal sequence homology. The large cleft that separates the two domains includes the catalytic center and permits a high degree of flexibility.


Pssm-ID: 340861 [Multi-domain]  Cd Length: 364  Bit Score: 38.45  E-value: 8.87e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74355480 356 DLLAhpSIRLFVTHGGQNSIMEAIQHGVPMVGI-PLFGDQPENMVRVEAKKFGVSIQLKKLKAETLALKMKQIMEDKRYK 434
Cdd:cd17507 263 ELMA--ASDLVITKPGGLTISEALARGLPVIIYdPIPGQEEENADFLENNGAGIIARDPEELLEIVARLIDPPSLLRMMS 340


                ....*.
gi 74355480 435 SAAVAA 440
Cdd:cd17507 341 EAAKEL 346
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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