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Conserved domains on  [gi|74310598|ref|YP_313731|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Cylindrophis ruffus]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009572)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-170 1.40e-30

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214424  Cd Length: 174  Bit Score: 109.07  E-value: 1.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598    1 MDYVFCLIMMLMVVVAVVLGTTPVSYYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSYCISVEKGVDNV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   81 FKLFVSKMFVCVS----VFVAAFFYLWIAVVFGLDGWLVVMDQDSFACVEVNGFGVLYFSGGAGLMVCVWGLLVTLFSIL 156
Cdd:MTH00115  81 AWGDWGVVGYVVGfvlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 74310598  157 VILSWHRLGGLRSF 170
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-170 1.40e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 109.07  E-value: 1.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598    1 MDYVFCLIMMLMVVVAVVLGTTPVSYYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSYCISVEKGVDNV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   81 FKLFVSKMFVCVS----VFVAAFFYLWIAVVFGLDGWLVVMDQDSFACVEVNGFGVLYFSGGAGLMVCVWGLLVTLFSIL 156
Cdd:MTH00115  81 AWGDWGVVGYVVGfvlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 74310598  157 VILSWHRLGGLRSF 170
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
 
Name Accession Description Interval E-value
ND6 MTH00115
NADH dehydrogenase subunit 6; Provisional
 1-170 1.40e-30

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214424  Cd Length: 174  Bit Score: 109.07  E-value: 1.40e-30
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598    1 MDYVFCLIMMLMVVVAVVLGTTPVSYYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSYCISVEKGVDNV 80
Cdd:MTH00115   1 MMYFVFLLGVCFVLGVVGVASNPSPYYGVVSLVLASVFGCGVLVSLGGSFVSLVLFLVYLGGMLVVFAYSVSLAADPYPE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   81 FKLFVSKMFVCVS----VFVAAFFYLWIAVVFGLDGWLVVMDQDSFACVEVNGFGVLYFSGGAGLMVCVWGLLVTLFSIL 156
Cdd:MTH00115  81 AWGDWGVVGYVVGfvlvVVVVGVVVGGLWGMEGVGVVTVDSGGLFVVRLDFSGVSLFYSSGGGGLLVCGWGLLLTLFVVL 160

                        170
                 ....*....|....
gi 74310598  157 VILSWHRLGGLRSF 170
Cdd:MTH00115 161 ELVRGLSRGALRAF 174
ND6 MTH00065
NADH dehydrogenase subunit 6; Provisional
 23-169 5.35e-08

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214415  Cd Length: 172  Bit Score: 49.85  E-value: 5.35e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   23 PVSYYGVIAL-MGFAFLCCVFMCFiSRTFVALVTYIVYLGGLVVVFSYCIS-VEKGVDNVFKLFVSKMFVCVSVFVAAFF 100
Cdd:MTH00065  23 PSPYFAALGLvLGAVCGCLVLVEL-GVSFLSLVLFLIYLGGMLVVFAYSAAlAAEPYPEAWGSWSVLVYVLFYLLLLIVG 101

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598  101 YLWIAVVFGLDGWLVVMDQDSFACV-EVNGFGVLYFSGGAGLMVCVWGLLVTLFSILVILSWHRLGGLRS 169
Cdd:MTH00065 102 YILFGCNFSLEFLFTNYDTEFSVVGyDWGGVGLMYSSGGWFLMISGWVLLLTLFVVLEVTRGLSRGSLRA 171
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 1-156 5.44e-08

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 49.75  E-value: 5.44e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598    1 MDYVFCLIMMLMVVVAVVLGTTPVSYYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSYCISV------E 74
Cdd:MTH00138   1 MTYLMSLFLLGLVLGLVAVASNPSPYFAALGLVVVAGVGCGVLVGHGGSFLSLVLFLIYLGGMLVVFAYSAALaaepypE 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   75 KGVDNVFKLFVSKMFVCVSVFVAAFFYLWIAVvfgldGWLVVMDQDSFA--CVEVNGFGVLYFSGGAGLMVCVWGLLVTL 152
Cdd:MTH00138  81 SWGSWSVLGYVVGYLVGVVLAAGLFWGGWYEG-----SWVVVDELKEFSvlRGDVGGVALMYSSGGGMLVICAWVLLLTL 155


                 ....
gi 74310598  153 FSIL 156
Cdd:MTH00138 156 FVVL 159
ND6 MTH00045
NADH dehydrogenase subunit 6; Validated
 26-168 5.37e-05

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 177120  Cd Length: 162  Bit Score: 41.43  E-value: 5.37e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   26 YYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSY--CISVEK--GVDNVFKLFvskmfvcvsvFVAAFFY 101
Cdd:MTH00045  24 YYSALGLVLVSLSGCLLLSLLGLSFLALLLLLIYMGGMLVVFVYssALSAERypSVSNLGEVL----------VLSLLLS 93

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 74310598  102 LWIAVVFGLDGWLVVMDQDSFACVEVNGFGVLYFSGGAGLMVCVWGLLVTLFSILVILSWHRLGGLR 168
Cdd:MTH00045  94 LWVFISFDNFLELSNNNWSLVSLSDLVGSSELYNSGGLYLLLGGFILLVALVVALVISFGHEYSSLR 160
ND6 MTH00214
NADH dehydrogenase subunit 6; Provisional
 26-160 6.31e-05

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214461  Cd Length: 168  Bit Score: 41.13  E-value: 6.31e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 74310598   26 YYGVIALMGFAFLCCVFMCFISRTFVALVTYIVYLGGLVVVFSYCIS-VEKGVDNVFKLFVSKMFVCVSVFVAAFFYLWI 104
Cdd:MTH00214  26 YFGALGLVLLALLGCFLLLSHGNSFLGLILFLIYLGGMLVVFSYSAAlAADPYPESWGGWSVLLFFLFYLLGLGFVGFYF 105

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*.
gi 74310598  105 AVVFGLDGWLVVMDQDSFacvEVNGFGVLYFSGGAGLMVCVWGLLVTLFSILVILS 160
Cdd:MTH00214 106 YGGWEMLSWMGVDEANNL---DLSGVSDLYSRGFFLLLLGGVVLFLVLFVVLELVR 158
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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