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unnamed protein product [Mus musculus]
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
ApaG | COG2967 | Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport ... |
283-404 | 1.97e-33 | |||
Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport and metabolism]; : Pssm-ID: 442207 Cd Length: 119 Bit Score: 122.51 E-value: 1.97e-33
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F-box_FBXO3 | cd22084 | F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called ... |
13-61 | 3.92e-27 | |||
F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. : Pssm-ID: 438856 Cd Length: 49 Bit Score: 103.11 E-value: 3.92e-27
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SMI1 super family | cl44049 | Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane ... |
94-190 | 6.06e-14 | |||
Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane/envelope biogenesis]; The actual alignment was detected with superfamily member COG4282: Pssm-ID: 443423 Cd Length: 188 Bit Score: 70.06 E-value: 6.06e-14
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Name | Accession | Description | Interval | E-value | |||
ApaG | COG2967 | Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport ... |
283-404 | 1.97e-33 | |||
Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport and metabolism]; Pssm-ID: 442207 Cd Length: 119 Bit Score: 122.51 E-value: 1.97e-33
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apaG | PRK05461 | CO2+/MG2+ efflux protein ApaG; Reviewed |
279-404 | 9.18e-33 | |||
CO2+/MG2+ efflux protein ApaG; Reviewed Pssm-ID: 180098 Cd Length: 127 Bit Score: 121.02 E-value: 9.18e-33
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DUF525 | pfam04379 | ApaG domain; The apaG domain is a ~125 amino acids domain present in bacterial apaG proteins ... |
294-382 | 5.95e-32 | |||
ApaG domain; The apaG domain is a ~125 amino acids domain present in bacterial apaG proteins and in eukaryotic F-box proteins. The domain is named after the bacterial apaG protein, of which it forms the core. The domain also occurs in the C-terminal part of eukaryotic proteins with an N-terminal F-box domain. The Salmonella typhimurium apaG domain protein corD is involved in Co(2+) resistance and Mg(2+) efflux. Tertiary structures from different apaG proteins show a fold of several beta-sheets. The apaG domain may be involved in protein-protein interactions which could be implicated in substrate-specificity. Pssm-ID: 461283 Cd Length: 87 Bit Score: 117.18 E-value: 5.95e-32
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F-box_FBXO3 | cd22084 | F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called ... |
13-61 | 3.92e-27 | |||
F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438856 Cd Length: 49 Bit Score: 103.11 E-value: 3.92e-27
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SMI1 | COG4282 | Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane ... |
94-190 | 6.06e-14 | |||
Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 443423 Cd Length: 188 Bit Score: 70.06 E-value: 6.06e-14
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SMI1_KNR4 | pfam09346 | SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1, ... |
121-249 | 3.32e-13 | |||
SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems. Pssm-ID: 430545 Cd Length: 120 Bit Score: 65.92 E-value: 3.32e-13
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F-box-like | pfam12937 | F-box-like; This is an F-box-like family. |
13-57 | 1.31e-10 | |||
F-box-like; This is an F-box-like family. Pssm-ID: 463757 [Multi-domain] Cd Length: 45 Bit Score: 56.34 E-value: 1.31e-10
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SMI1_KNR4 | smart00860 | SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan ... |
121-249 | 6.28e-08 | |||
SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Pssm-ID: 214864 Cd Length: 127 Bit Score: 51.10 E-value: 6.28e-08
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FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
16-56 | 2.55e-04 | |||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 38.57 E-value: 2.55e-04
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Name | Accession | Description | Interval | E-value | |||
ApaG | COG2967 | Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport ... |
283-404 | 1.97e-33 | |||
Uncharacterized conserved protein ApaG affecting Mg2+/Co2+ transport [Inorganic ion transport and metabolism]; Pssm-ID: 442207 Cd Length: 119 Bit Score: 122.51 E-value: 1.97e-33
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apaG | PRK05461 | CO2+/MG2+ efflux protein ApaG; Reviewed |
279-404 | 9.18e-33 | |||
CO2+/MG2+ efflux protein ApaG; Reviewed Pssm-ID: 180098 Cd Length: 127 Bit Score: 121.02 E-value: 9.18e-33
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DUF525 | pfam04379 | ApaG domain; The apaG domain is a ~125 amino acids domain present in bacterial apaG proteins ... |
294-382 | 5.95e-32 | |||
ApaG domain; The apaG domain is a ~125 amino acids domain present in bacterial apaG proteins and in eukaryotic F-box proteins. The domain is named after the bacterial apaG protein, of which it forms the core. The domain also occurs in the C-terminal part of eukaryotic proteins with an N-terminal F-box domain. The Salmonella typhimurium apaG domain protein corD is involved in Co(2+) resistance and Mg(2+) efflux. Tertiary structures from different apaG proteins show a fold of several beta-sheets. The apaG domain may be involved in protein-protein interactions which could be implicated in substrate-specificity. Pssm-ID: 461283 Cd Length: 87 Bit Score: 117.18 E-value: 5.95e-32
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F-box_FBXO3 | cd22084 | F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called ... |
13-61 | 3.92e-27 | |||
F-box domain found in F-box only protein 3 (FBXO3) and similar proteins; FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438856 Cd Length: 49 Bit Score: 103.11 E-value: 3.92e-27
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SMI1 | COG4282 | Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane ... |
94-190 | 6.06e-14 | |||
Cell wall assembly regulator SMI1 (Killer toxin-resistance protein 4) [Cell wall/membrane/envelope biogenesis]; Pssm-ID: 443423 Cd Length: 188 Bit Score: 70.06 E-value: 6.06e-14
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SMI1_KNR4 | pfam09346 | SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1, ... |
121-249 | 3.32e-13 | |||
SMI1 / KNR4 family (SUKH-1); Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Genome contextual information showed that SMI1 are primary immunity proteins in bacterial toxin systems. Pssm-ID: 430545 Cd Length: 120 Bit Score: 65.92 E-value: 3.32e-13
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F-box-like | pfam12937 | F-box-like; This is an F-box-like family. |
13-57 | 1.31e-10 | |||
F-box-like; This is an F-box-like family. Pssm-ID: 463757 [Multi-domain] Cd Length: 45 Bit Score: 56.34 E-value: 1.31e-10
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SMI1_KNR4 | smart00860 | SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan ... |
121-249 | 6.28e-08 | |||
SMI1 / KNR4 family; Proteins in this family are involved in the regulation of 1,3-beta-glucan synthase activity and cell-wall formation. Pssm-ID: 214864 Cd Length: 127 Bit Score: 51.10 E-value: 6.28e-08
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F-box | pfam00646 | F-box domain; This domain is approximately 50 amino acids long, and is usually found in the ... |
13-55 | 9.11e-08 | |||
F-box domain; This domain is approximately 50 amino acids long, and is usually found in the N-terminal half of a variety of proteins. Two motifs that are commonly found associated with the F-box domain are the leucine rich repeats (LRRs; pfam00560 and pfam07723) and the WD repeat (pfam00400). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 425796 Cd Length: 43 Bit Score: 48.30 E-value: 9.11e-08
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F-box_FBXW4 | cd20090 | F-box domain found in F-box/WD repeat-containing protein 4 (FBXW4) and similar proteins; FBXW4, ... |
12-58 | 1.14e-06 | |||
F-box domain found in F-box/WD repeat-containing protein 4 (FBXW4) and similar proteins; FBXW4, also called dactylin, or F-box and WD-40 domain-containing protein 4, probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. It is likely to be involved in key signaling pathways crucial for normal limb development. It may participate in Wnt signaling and act as a novel tumor suppressor that regulates important cellular processes. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438853 Cd Length: 47 Bit Score: 45.28 E-value: 1.14e-06
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F-box_SF | cd09917 | F-box domain superfamily; This short domain is commonly found at the N-terminus of various ... |
14-48 | 3.26e-06 | |||
F-box domain superfamily; This short domain is commonly found at the N-terminus of various proteins, and typically co-occurs with one or more other conserved domains or motifs, such as leucine rich repeats, WD40 repeats, kelch, tub, spry, and others. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. One of the best researched roles of F-box proteins is their participation in SCF (Skp1-Cul1-F-box protein), a multi-protein complex that functions as a ubiquitin E3 ligase, where the role of the F-box protein is to recruit target substrates. Gene families containing the F-box are found greatly expanded in narrow taxonomic lineages, such as flowering plants and nematodes. In this hierarchical classification, many of the subfamilies are named according to their domain architectures. Pssm-ID: 438852 Cd Length: 35 Bit Score: 43.59 E-value: 3.26e-06
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F-box_FBXO15 | cd22093 | F-box domain found in F-box only protein 15 (FBXO15) and similar proteins; FBXO15, also called ... |
13-58 | 6.56e-06 | |||
F-box domain found in F-box only protein 15 (FBXO15) and similar proteins; FBXO15, also called FBX15, has a novel dual molecular function by controlling transcriptional repression and being part of SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligases, which is essential for stress response, gliotoxin production and virulence in the opportunistic human pathogen Aspergillus fumigatus. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438865 Cd Length: 46 Bit Score: 43.01 E-value: 6.56e-06
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F-box_unchar | cd22139 | F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 ... |
16-57 | 7.04e-06 | |||
F-box domain found in uncharacterized F-box protein group similar to F-box only protein 3 (FBXO3); This subfamily corresponds to a group of uncharacterized F-box proteins which show sequence similarity to F-box only protein 3 (FBXO3). FBXO3, also called FBX3, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex, that mediates the ubiquitination of HIPK2 and probably that of EP300, leading to rapid degradation by the proteasome. It also promotes ubiquitylation and transcriptional activity of AIRE (autoimmune regulator). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438911 Cd Length: 45 Bit Score: 43.00 E-value: 7.04e-06
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F-box_FBXO4 | cd22085 | F-box domain found in F-box only protein 4 (FBXO4) and similar proteins; FBXO4, also called ... |
12-57 | 4.88e-05 | |||
F-box domain found in F-box only protein 4 (FBXO4) and similar proteins; FBXO4, also called FBX4, is a specific substrate-recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex that catalyzes the ubiquitination and subsequent degradation of cyclin D1 and Trx1. It recognizes TERF1 and promotes its ubiquitination together with UBE2D1. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438857 Cd Length: 50 Bit Score: 40.86 E-value: 4.88e-05
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F-box_ScMDM30-like | cd22143 | F-box domain found in Saccharomyces cerevisiae mitochondrial distribution and morphology ... |
12-55 | 5.59e-05 | |||
F-box domain found in Saccharomyces cerevisiae mitochondrial distribution and morphology protein 30 (ScMDM30) and similar proteins; ScMDM30 is an F-box protein required for maintenance of fusion-competent mitochondria in yeast. It is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins. ScMDM30 recognizes FZO1 and regulates the amount of FZO1. It acts as a regulatory factor for the mitochondrial fusion machinery and is required for mitochondrial DNA maintenance. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438915 Cd Length: 44 Bit Score: 40.29 E-value: 5.59e-05
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F-box_FBXW12 | cd22137 | F-box domain found in F-box/WD repeat-containing protein 12 (FBXW12) and similar proteins; ... |
15-57 | 7.30e-05 | |||
F-box domain found in F-box/WD repeat-containing protein 12 (FBXW12) and similar proteins; FBXW12, also called F-box and WD-40 domain-containing protein 12, or F-box only protein 35 (FBXO35), is the substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex that mediates the ubiquitination and subsequent proteasomal degradation of target proteins. It functions as an epithelial growth suppressor. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438909 Cd Length: 44 Bit Score: 40.05 E-value: 7.30e-05
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F-box_FBXO31 | cd22102 | F-box domain found in F-box only protein 31 (FBXO31) and similar proteins; FBXO31, also called ... |
15-58 | 1.28e-04 | |||
F-box domain found in F-box only protein 31 (FBXO31) and similar proteins; FBXO31, also called FBX31, or FBXO14, is a component of an SCF (SKP1-cullin-F-box) protein ligase complex that plays a central role in G1 arrest following DNA damage. It specifically recognizes phosphorylated cyclin-D1 (CCND1), promoting its ubiquitination and degradation by the proteasome, resulting in G1 arrest. FBXO31 may act as a tumor suppressor. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438874 Cd Length: 48 Bit Score: 39.33 E-value: 1.28e-04
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F-box_SpPof1-like | cd22147 | F-box domain found in Schizosaccharomyces pombe Skp1-binding protein 1 (SpPof1) and similar ... |
13-57 | 1.31e-04 | |||
F-box domain found in Schizosaccharomyces pombe Skp1-binding protein 1 (SpPof1) and similar proteins; SpPof1, also called F-box/WD repeat-containing protein pof1, probably recognizes and binds to some phosphorylated proteins and promotes their ubiquitination and degradation. It is required for the inactivation of zip1 via ubiquitination. This subfamily also includes Saccharomyces cerevisiae methionine-requiring protein 30 (ScMET30, also called E3 ubiquitin ligase complex SCF(Met30) subunit MET30), Aspergillus niger sulfur controller B (AnSCONB, also called sulfur metabolite repression control protein B) and Neurospora crassa sulfur controller 2 (NcSCON2, also called sulfur metabolite repression control protein 2). ScMET30 acts as a transcriptional inhibitor that negatively regulates the expression of sulfur amino acid biosynthesis genes. It controls cell cycle function (being required for the G1/S transition and M-phase but not the S-phase), sulfur metabolism, and methionine biosynthesis as part of the E3 ubiquitin ligase complex SCF(Met30). AnSCONB and NcSCON2 are components of the SCF (sconB/scon-2) E3 ubiquitin ligase complexes involved in the regulation of sulfur metabolite repression, probably by mediating the inactivation or degradation of the metR transcription factor. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438918 Cd Length: 46 Bit Score: 39.60 E-value: 1.31e-04
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FBOX | smart00256 | A Receptor for Ubiquitination Targets; |
16-56 | 2.55e-04 | |||
A Receptor for Ubiquitination Targets; Pssm-ID: 197608 Cd Length: 41 Bit Score: 38.57 E-value: 2.55e-04
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F-box_FBXO6-like | cd22168 | F-box domain found in F-box only proteins FBXO6, FBXO44 and similar proteins; This subfamily ... |
11-76 | 3.04e-04 | |||
F-box domain found in F-box only proteins FBXO6, FBXO44 and similar proteins; This subfamily includes FBXO6 and FBXO44. FBXO6, also called FBX6, F-box protein that recognizes sugar chains 2 (FBS2), or F-box/G-domain protein 2 (FBG2), is a substrate-recognition component of SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes. It is involved in the endoplasmic reticulum-associated degradation pathway (ERAD) for misfolded lumenal proteins, by recognizing and binding sugar chains on unfolded glycoproteins that are retro-translocated into the cytosol and promoting their ubiquitination and subsequent degradation. FBXO6 can recognize and bind denatured glycoproteins, which are modified with not only high-mannose but also complex-type oligosaccharides. It also recognizes sulfated glycans. FBXO6 is involved in DNA damage response by specifically recognizing activated CHEK1 (phosphorylated on 'Ser-345'), promoting its ubiquitination and degradation. FBXO44, also called FBXO6A, FBX44, or F-box/G-domain protein 3 (FBG3), is a substrate-recognition component of an SCF-type E3 ubiquitin ligase complex. It interacts with SKP1 and CUL1. FBXO44 mediates BRCA1 ubiquitination and degradation. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438939 [Multi-domain] Cd Length: 82 Bit Score: 39.57 E-value: 3.04e-04
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F-box_DdgacFF-like | cd22148 | F-box domain found in Dictyostelium discoideum Rho GTPase-activating protein gacFF (DdgacFF) ... |
16-55 | 3.22e-04 | |||
F-box domain found in Dictyostelium discoideum Rho GTPase-activating protein gacFF (DdgacFF) and similar proteins; DdgacFF, also called GTPase activating factor for raC protein FF, is a Rho GTPase-activating protein involved in the signal transduction pathway. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438919 Cd Length: 44 Bit Score: 38.42 E-value: 3.22e-04
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F-box_FBXO41 | cd22109 | F-box domain found in F-box only protein 41 (FBXO41) and similar proteins; FBXO41, also called ... |
13-57 | 3.48e-04 | |||
F-box domain found in F-box only protein 41 (FBXO41) and similar proteins; FBXO41, also called FBX41, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It acts as a novel central nervous system (CNS)-specific F-box protein that localizes to the centrosome and the cytoplasm of neurons and promotes neuronal migration. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438881 Cd Length: 47 Bit Score: 38.08 E-value: 3.48e-04
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F-box_FBXO17-like | cd22169 | F-box domain found in F-box only protein 17 (FBXO17), F-box only protein 27 (FBXO27) and ... |
13-57 | 1.97e-03 | |||
F-box domain found in F-box only protein 17 (FBXO17), F-box only protein 27 (FBXO27) and similar proteins; This subfamily includes FBXO17 and FBXO27. FBXO17 is also called FBX17, F-box only protein 26 (FBX26/FBXO26), or FBG4, while FBXO27 is also called FBX27, or F-box/G-domain protein 5. FBXO17 and FBXO27 are the substrate-recognition components of SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complexes. They can recognize and bind denatured glycoproteins, which are modified with complex-type oligosaccharides. FBXO17 also recognizes sulfated glycans but does not bind high-mannose glycoproteins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438940 Cd Length: 48 Bit Score: 36.25 E-value: 1.97e-03
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F-box_FBXO36 | cd22106 | F-box domain found in F-box only protein 36 (FBXO36) and similar proteins; FBXO36, also called ... |
13-55 | 2.12e-03 | |||
F-box domain found in F-box only protein 36 (FBXO36) and similar proteins; FBXO36, also called FBX36, likely functions as the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438878 Cd Length: 46 Bit Score: 36.01 E-value: 2.12e-03
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F-box_FBXW8 | cd22134 | F-box domain found in F-box/WD repeat-containing protein 8 (FBXW8) and similar proteins; FBXW8, ... |
15-57 | 2.37e-03 | |||
F-box domain found in F-box/WD repeat-containing protein 8 (FBXW8) and similar proteins; FBXW8, also called F-box and WD-40 domain-containing protein 8, or F-box only protein 29 (FBXO29), is the substrate-recognition component of a Cul7-RING ubiquitin-protein ligase complex, which mediates the ubiquitination and subsequent proteasomal degradation of target proteins, such as GORASP1, IRS1, MAP4K1/HPK1. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438906 Cd Length: 48 Bit Score: 35.82 E-value: 2.37e-03
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F-box_AtSKIP22-like | cd22165 | F-box domain found in Arabidopsis thaliana SKP1-interacting partner 22 (AtSKIP22) and similar ... |
13-57 | 3.40e-03 | |||
F-box domain found in Arabidopsis thaliana SKP1-interacting partner 22 (AtSKIP22) and similar proteins; AtSKIP22, also called F-box protein SKIP22, is a component of SCF (SKP1/ASK-cullin-F-box protein) E3 ubiquitin ligase complexes, which may mediate the ubiquitination and subsequent proteasomal degradation of target proteins. It interacts with SKP1A/ASK1 and SPK1B/ASK2. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438936 Cd Length: 46 Bit Score: 35.33 E-value: 3.40e-03
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F-box_FBXW2 | cd22131 | F-box domain found in F-box/WD repeat-containing protein 2 (FBXW2) and similar proteins; FBXW2, ... |
16-41 | 4.82e-03 | |||
F-box domain found in F-box/WD repeat-containing protein 2 (FBXW2) and similar proteins; FBXW2, also called F-box and WD-40 domain-containing protein 2, or protein MD6, is the substrate-recognition component of an SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. It acts as a tumor suppressor by promoting SKP2 degradation. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438903 Cd Length: 40 Bit Score: 35.00 E-value: 4.82e-03
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F-box_FBXO1 | cd22082 | F-box domain found in F-box only protein 1 (FBXO1) and similar proteins; FBXO1, also called ... |
12-55 | 6.75e-03 | |||
F-box domain found in F-box only protein 1 (FBXO1) and similar proteins; FBXO1, also called FBX1, or cyclin-F, is a substrate-recognition component of an SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of CP110 during G2 phase, thereby acting as an inhibitor of centrosome reduplication. It is the largest among all cyclins and oscillates in the cell cycle like other cyclins. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438854 Cd Length: 52 Bit Score: 34.91 E-value: 6.75e-03
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F-box_AtGID2-like | cd22151 | F-box domain found in Arabidopsis thaliana F-box protein GID2 and similar proteins; AtGID2, ... |
15-57 | 6.85e-03 | |||
F-box domain found in Arabidopsis thaliana F-box protein GID2 and similar proteins; AtGID2, also called protein SLEEPY 1, is an essential component of the SCF-type E3 ligase complex, SCF(GID2), a complex that positively regulates the gibberellin signaling pathway. Upon gibberellin treatment, the SCF(GID2) complex mediates the ubiquitination and subsequent degradation of DELLA proteins (GAI, RGA and RGL2), some repressors of the gibberellin pathway, leading to the activation of the pathway. The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438922 Cd Length: 44 Bit Score: 34.60 E-value: 6.85e-03
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F-box_FBXO48 | cd22113 | F-box domain found in F-box only protein 48 (FBXO48) and similar proteins; FBXO48, also called ... |
13-57 | 8.77e-03 | |||
F-box domain found in F-box only protein 48 (FBXO48) and similar proteins; FBXO48, also called FBX48, is one of the paralogs of the F-box only protein 7 (FBXO7), which is the causative gene for PARK15 (also known as Parkinsonian-pyramidal disease, PPD). The F-box domain has a role in mediating protein-protein interactions in a variety of contexts, such as polyubiquitination, transcription elongation, centromere binding and translational repression. Pssm-ID: 438885 Cd Length: 46 Bit Score: 34.21 E-value: 8.77e-03
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