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Conserved domains on  [gi|742160602|ref|XP_010847134|]
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PREDICTED: nuclear pore complex protein Nup153 [Bison bison bison]

Protein Classification

zinc finger Ran-binding domain-containing protein( domain architecture ID 13755470)

zinc finger Ran-binding domain-containing protein similar to Arabidopsis thaliana chloroplastic zinc finger protein VAR3, which is involved in C-to-U editing of chloroplastic RNA

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Nup153 pfam08604
Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and ...
 176-684 0e+00

Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and Nup154 from fission yeast. These have been demonstrated to be functionally equivalent.


:

Pssm-ID: 462533 [Multi-domain]  Cd Length: 507  Bit Score: 692.78  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   176 PSTTSTASNYPDVLTRPSLHRSHLNFSMLDSPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 255
Cdd:pfam08604    1 PSTSRSALNFQDVLTRPSLHRSHLNFTVLDSPALFCQPSTSTAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   256 DKDIAVSKNTSVPPLWSPEAERSHSFSQHTATSSKKPAFNLSAFGALSPSLGNSSIFKTSQLGDSPFYPGKTTYGGaAAA 335
Cdd:pfam08604   81 DKDIPVSKTVSLPLLWSPEAERSHSLSQHSASSSKKPAFNLSAFGTLSPSLGNSSVLNTSQLGDSPFYPGKTTYGG-AAA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   336 VRQSKLRNTPYQAPVRRQMKAKQPSAQAYGVTSSTARRILQSLEKMSSPLADAKRIPS-VFSSLNSPLDRSGMDtTTDFQ 414
Cdd:pfam08604  160 VRSSRVRGTPYQAPVRRQIKAKPANAQSYGVTSSTARRILQSLEKMSSPLADAKRIPStVSSPLSSPLDRSDLD-ITNFQ 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   415 AKREKVDSQYPPVQRLMIPKPVSIAANRTVYFKPSLTPSGELRKTNQRIDKKYStDYEKNTTPGQNREQQESGFSYPNFS 494
Cdd:pfam08604  239 SKRKKVDSQYPPVQKLVTPKAISVSGNRSVYFKPSLTPSGQSNKTSRRVDKDHR-ETEVRQSPEQAVEPSESSLSYPKFS 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   495 MSAANGLSPGVGGGGGKMRRERTRVVASKPQEKEEV-EVPVLPKISLPITSSSLPTFNFSSSVITTSSPSPISPSQSLTN 573
Cdd:pfam08604  318 TPASNSLSSGGNGGGGKMRRERGRRPSSKPAEEDEVvEVPVLPKISLPISTASLPTFNFSSPTSSTSSSSPPSVTKSAEN 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   574 KVQVTSPNSTGSPLFRFSSPIVKSTESDVLPP-SSIGFTFSVPVAKTAELSGPSSVsePITSSSAQDTTAVNSTSCKKKQ 652
Cdd:pfam08604  398 KAQKQPPSTSGSPAFTFSSPIVKSTEASVPPPsPSIGFTFSVPVAKTAELSGSSGT--SVVSVVSTETTTVNSTSNKKEE 475

                          490       500       510
                   ....*....|....*....|....*....|..
gi 742160602   653 DEDCESPFRVAKTLKEGSVLDVLKSPGFASSK 684
Cdd:pfam08604  476 EEEFEGPFKPAKVLKQGSVLDILKSPGFASPK 507
Nup_retrotrp_bd pfam10599
Retro-transposon transporting motif; This is the highly conserved C-terminal motif ...
 1455-1542 3.24e-19

Retro-transposon transporting motif; This is the highly conserved C-terminal motif GRKIxxxxxRRKx of nucleoporins that plays a critical and unique role in the nuclear import of retro-transposons in both yeasts and higher organizms. It would appear that the arginine residues at positions 2 and 9-10 constitute a bipartite nuclear localization signal, with two basic peptide motifs separated by an interchangeable spacer sequence, that is crucial for the retro-transposon activity.


:

Pssm-ID: 371156  Cd Length: 86  Bit Score: 83.57  E-value: 3.24e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1455 PNPSSVFQFGSSTaTNFNFTNSSPSGVFTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMfsssgPSVSGRKI 1534
Cdd:pfam10599    5 PDPASVFGFGSSN-TNFNFTNNNPSTPFGFGASPSTPQAANPPSAFTPPAFSQSPASFNVGSNGSNM-----FSVSGRKI 78


                   ....*...
gi 742160602  1535 KTAVRRKK 1542
Cdd:pfam10599   79 AQMRRRRR 86
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
787-815 2.14e-09

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 53.90  E-value: 2.14e-09
                           10        20
                   ....*....|....*....|....*....
gi 742160602   787 VGTWDCDTCLVQNKPEAIKCVACETPKPG 815
Cdd:pfam00641    2 EGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
857-886 8.73e-09

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 52.35  E-value: 8.73e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 742160602   857 PVGSWECPVCCVSNNAEDNKCVSCMSEKPG 886
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
916-944 3.14e-08

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 50.81  E-value: 3.14e-08
                           10        20
                   ....*....|....*....|....*....
gi 742160602   916 PEGSWNCEVCLVQNKADSTKCIACETVKS 944
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
724-750 3.33e-07

Zn-finger in Ran binding protein and others;


:

Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 47.73  E-value: 3.33e-07
                           10        20
                   ....*....|....*....|....*..
gi 742160602   724 SWQCDTCLLQNKVTDNKCVACQATKLL 750
Cdd:pfam00641    4 DWDCSKCLVQNFATSTKCVACQAPKPD 30
PPE super family cl35037
PPE-repeat protein [Function unknown];
1284-1494 2.87e-05

PPE-repeat protein [Function unknown];


The actual alignment was detected with superfamily member COG5651:

Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 48.35  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1284 SPSAPVAAFVFGqASNPVSSSAFANAAESSTSQSLLFSQESKPATTSSTGTAVTPFVFGTGASSNNTATSGFNFGATTTS 1363
Cdd:COG5651   176 NPGGLLGAQNAG-SGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAAGAAAAAAAAAAAAGAG 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1364 SSAGSSFVFGTGASAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPPTFGTVSSSGQPPVFGQQ 1443
Cdd:COG5651   255 ASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAA 334

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 742160602 1444 PGQSAFGSGTAPNPSSVFQFGSSTATNFNFTNSSPSGVFTFGASPSTPAAS 1494
Cdd:COG5651   335 AAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
 
Name Accession Description Interval E-value
Nup153 pfam08604
Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and ...
 176-684 0e+00

Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and Nup154 from fission yeast. These have been demonstrated to be functionally equivalent.


Pssm-ID: 462533 [Multi-domain]  Cd Length: 507  Bit Score: 692.78  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   176 PSTTSTASNYPDVLTRPSLHRSHLNFSMLDSPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 255
Cdd:pfam08604    1 PSTSRSALNFQDVLTRPSLHRSHLNFTVLDSPALFCQPSTSTAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   256 DKDIAVSKNTSVPPLWSPEAERSHSFSQHTATSSKKPAFNLSAFGALSPSLGNSSIFKTSQLGDSPFYPGKTTYGGaAAA 335
Cdd:pfam08604   81 DKDIPVSKTVSLPLLWSPEAERSHSLSQHSASSSKKPAFNLSAFGTLSPSLGNSSVLNTSQLGDSPFYPGKTTYGG-AAA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   336 VRQSKLRNTPYQAPVRRQMKAKQPSAQAYGVTSSTARRILQSLEKMSSPLADAKRIPS-VFSSLNSPLDRSGMDtTTDFQ 414
Cdd:pfam08604  160 VRSSRVRGTPYQAPVRRQIKAKPANAQSYGVTSSTARRILQSLEKMSSPLADAKRIPStVSSPLSSPLDRSDLD-ITNFQ 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   415 AKREKVDSQYPPVQRLMIPKPVSIAANRTVYFKPSLTPSGELRKTNQRIDKKYStDYEKNTTPGQNREQQESGFSYPNFS 494
Cdd:pfam08604  239 SKRKKVDSQYPPVQKLVTPKAISVSGNRSVYFKPSLTPSGQSNKTSRRVDKDHR-ETEVRQSPEQAVEPSESSLSYPKFS 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   495 MSAANGLSPGVGGGGGKMRRERTRVVASKPQEKEEV-EVPVLPKISLPITSSSLPTFNFSSSVITTSSPSPISPSQSLTN 573
Cdd:pfam08604  318 TPASNSLSSGGNGGGGKMRRERGRRPSSKPAEEDEVvEVPVLPKISLPISTASLPTFNFSSPTSSTSSSSPPSVTKSAEN 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   574 KVQVTSPNSTGSPLFRFSSPIVKSTESDVLPP-SSIGFTFSVPVAKTAELSGPSSVsePITSSSAQDTTAVNSTSCKKKQ 652
Cdd:pfam08604  398 KAQKQPPSTSGSPAFTFSSPIVKSTEASVPPPsPSIGFTFSVPVAKTAELSGSSGT--SVVSVVSTETTTVNSTSNKKEE 475

                          490       500       510
                   ....*....|....*....|....*....|..
gi 742160602   653 DEDCESPFRVAKTLKEGSVLDVLKSPGFASSK 684
Cdd:pfam08604  476 EEEFEGPFKPAKVLKQGSVLDILKSPGFASPK 507
Nup_retrotrp_bd pfam10599
Retro-transposon transporting motif; This is the highly conserved C-terminal motif ...
 1455-1542 3.24e-19

Retro-transposon transporting motif; This is the highly conserved C-terminal motif GRKIxxxxxRRKx of nucleoporins that plays a critical and unique role in the nuclear import of retro-transposons in both yeasts and higher organizms. It would appear that the arginine residues at positions 2 and 9-10 constitute a bipartite nuclear localization signal, with two basic peptide motifs separated by an interchangeable spacer sequence, that is crucial for the retro-transposon activity.


Pssm-ID: 371156  Cd Length: 86  Bit Score: 83.57  E-value: 3.24e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1455 PNPSSVFQFGSSTaTNFNFTNSSPSGVFTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMfsssgPSVSGRKI 1534
Cdd:pfam10599    5 PDPASVFGFGSSN-TNFNFTNNNPSTPFGFGASPSTPQAANPPSAFTPPAFSQSPASFNVGSNGSNM-----FSVSGRKI 78


                   ....*...
gi 742160602  1535 KTAVRRKK 1542
Cdd:pfam10599   79 AQMRRRRR 86
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
787-815 2.14e-09

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 53.90  E-value: 2.14e-09
                           10        20
                   ....*....|....*....|....*....
gi 742160602   787 VGTWDCDTCLVQNKPEAIKCVACETPKPG 815
Cdd:pfam00641    2 EGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
857-886 8.73e-09

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 52.35  E-value: 8.73e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 742160602   857 PVGSWECPVCCVSNNAEDNKCVSCMSEKPG 886
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
916-944 3.14e-08

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 50.81  E-value: 3.14e-08
                           10        20
                   ....*....|....*....|....*....
gi 742160602   916 PEGSWNCEVCLVQNKADSTKCIACETVKS 944
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
724-750 3.33e-07

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 47.73  E-value: 3.33e-07
                           10        20
                   ....*....|....*....|....*..
gi 742160602   724 SWQCDTCLLQNKVTDNKCVACQATKLL 750
Cdd:pfam00641    4 DWDCSKCLVQNFATSTKCVACQAPKPD 30
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 918-942 2.35e-06

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 45.39  E-value: 2.35e-06
                            10        20
                    ....*....|....*....|....*
gi 742160602    918 GSWNCEVCLVQNKADSTKCIACETV 942
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 788-812 7.09e-06

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 43.85  E-value: 7.09e-06
                            10        20
                    ....*....|....*....|....*
gi 742160602    788 GTWDCDTCLVQNKPEAIKCVACETP 812
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGAP 25
PPE COG5651
PPE-repeat protein [Function unknown];
1284-1494 2.87e-05

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 48.35  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1284 SPSAPVAAFVFGqASNPVSSSAFANAAESSTSQSLLFSQESKPATTSSTGTAVTPFVFGTGASSNNTATSGFNFGATTTS 1363
Cdd:COG5651   176 NPGGLLGAQNAG-SGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAAGAAAAAAAAAAAAGAG 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1364 SSAGSSFVFGTGASAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPPTFGTVSSSGQPPVFGQQ 1443
Cdd:COG5651   255 ASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAA 334

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 742160602 1444 PGQSAFGSGTAPNPSSVFQFGSSTATNFNFTNSSPSGVFTFGASPSTPAAS 1494
Cdd:COG5651   335 AAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 1320-1509 6.05e-05

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 47.74  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1320 FSQESKPATTSSTGTavtPFVFGTGASSNNTATSGFNFGATTTSSSAGSS--------------------FVFGTGASAp 1379
Cdd:pfam15967    4 FSFGGGPGSTATAGG---GFSFGAAAASNPGSTGGFSFGTLGAAPAATATtttatlglggglfgqkpatgFTFGTPASS- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1380 SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPP---TFGTVSSSGQPpvfgqQPGQSAF--GSGTA 1454
Cdd:pfam15967   80 TAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASSTSGgglSLGSVLTSTAA-----QQGATGFtlNLGGT 154

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742160602  1455 PNPSSVFQFGSSTATNFN------FTNSSPSGV------FTFGASPSTPAASSQPS-GSGGFQFSQSS 1509
Cdd:pfam15967  155 PATTTAVSTGLSLGSTLTslggslFQNTNSTGLgqttlgLTLLATSTAPVSAPAASeGLGGLDFSTSS 222
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 723-746 2.91e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 39.22  E-value: 2.91e-04
                            10        20
                    ....*....|....*....|....
gi 742160602    723 SSWQCDTCLLQNKVTDNKCVACQA 746
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGA 24
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 859-880 5.73e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 38.45  E-value: 5.73e-04
                            10        20
                    ....*....|....*....|..
gi 742160602    859 GSWECPVCCVSNNAEDNKCVSC 880
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFAC 22
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 1277-1497 2.15e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 42.55  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1277 IFGSSTSSPSAPVAAFVFGQASNPVSSSAFANAAESSTSQ-------SLLFSQESKPATTSSTGTavtpfvFGTGASSNN 1349
Cdd:cd23959    45 VFAARPSDQEEPLYGAVSPEGENPFDGPGLVTASTVSDCYvgnanfyEVDMSDAFAMAPDESLGP------FRAARVPNP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1350 TATSGFNFGATTTSSSAGSSFVfgtgasAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSgalFSAGSQPAPPTFG 1429
Cdd:cd23959   119 FSASSSTQRETHKTAQVAPPKA------EPQTAPVTPFGQLPMFGQHPPPAKPLPAAAAAQQSS---ASPGEVASPFASG 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742160602 1430 TVSSsgqppvfgqqpgqSAFGSGTAPNPSSVFQFGSSTATNFNFTNSSPSGVFTFGASPSTPAASSQP 1497
Cdd:cd23959   190 TVSA-------------SPFATATDTAPSSGAPDGFPAEASAPSPFAAPASAASFPAAPVANGEAATP 244
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 1307-1530 8.48e-03

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 40.76  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1307 ANAAES-STSQSLLFSQESKPATTSSTGTAVTpfvFGTGASSNNTATSGFNfgatttsSSAGSSFVFGTGASAP-SASPA 1384
Cdd:NF033849  233 ANLGQSaGTGYGESVGHSTSQGQSHSVGTSES---HSVGTSQSQSHTTGHG-------STRGWSHTQSTSESEStGQSSS 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1385 FGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGsqpappTFGTVSSSGQPPVFGQQPGQSAFGSGTAPNPSSVFQFG 1464
Cdd:NF033849  303 VGTSESQSHGTTEGTSTTDSSSHSQSSSYNVSSGTG------VSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVS 376

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742160602 1465 SSTATNFNFTNSS---------PSGVFTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMFSSSGPSVS 1530
Cdd:NF033849  377 SSESSSRSSSSGVsggfsggiaGGGVTSEGLGASQGGSEGWGSGDSVQSVSQSYGSSSSTGTSSGHSDSSSHSTS 451
 
Name Accession Description Interval E-value
Nup153 pfam08604
Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and ...
 176-684 0e+00

Nucleoporin Nup153-like; This family contains both the nucleoporin Nup153 from human and Nup154 from fission yeast. These have been demonstrated to be functionally equivalent.


Pssm-ID: 462533 [Multi-domain]  Cd Length: 507  Bit Score: 692.78  E-value: 0e+00
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   176 PSTTSTASNYPDVLTRPSLHRSHLNFSMLDSPALHCQPSTSSAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 255
Cdd:pfam08604    1 PSTSRSALNFQDVLTRPSLHRSHLNFTVLDSPALFCQPSTSTAFPIGSSGFSLVKEIKDSTSQHDDDNISTTSGFSSRAS 80

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   256 DKDIAVSKNTSVPPLWSPEAERSHSFSQHTATSSKKPAFNLSAFGALSPSLGNSSIFKTSQLGDSPFYPGKTTYGGaAAA 335
Cdd:pfam08604   81 DKDIPVSKTVSLPLLWSPEAERSHSLSQHSASSSKKPAFNLSAFGTLSPSLGNSSVLNTSQLGDSPFYPGKTTYGG-AAA 159

                          170       180       190       200       210       220       230       240
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   336 VRQSKLRNTPYQAPVRRQMKAKQPSAQAYGVTSSTARRILQSLEKMSSPLADAKRIPS-VFSSLNSPLDRSGMDtTTDFQ 414
Cdd:pfam08604  160 VRSSRVRGTPYQAPVRRQIKAKPANAQSYGVTSSTARRILQSLEKMSSPLADAKRIPStVSSPLSSPLDRSDLD-ITNFQ 238

                          250       260       270       280       290       300       310       320
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   415 AKREKVDSQYPPVQRLMIPKPVSIAANRTVYFKPSLTPSGELRKTNQRIDKKYStDYEKNTTPGQNREQQESGFSYPNFS 494
Cdd:pfam08604  239 SKRKKVDSQYPPVQKLVTPKAISVSGNRSVYFKPSLTPSGQSNKTSRRVDKDHR-ETEVRQSPEQAVEPSESSLSYPKFS 317

                          330       340       350       360       370       380       390       400
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   495 MSAANGLSPGVGGGGGKMRRERTRVVASKPQEKEEV-EVPVLPKISLPITSSSLPTFNFSSSVITTSSPSPISPSQSLTN 573
Cdd:pfam08604  318 TPASNSLSSGGNGGGGKMRRERGRRPSSKPAEEDEVvEVPVLPKISLPISTASLPTFNFSSPTSSTSSSSPPSVTKSAEN 397

                          410       420       430       440       450       460       470       480
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602   574 KVQVTSPNSTGSPLFRFSSPIVKSTESDVLPP-SSIGFTFSVPVAKTAELSGPSSVsePITSSSAQDTTAVNSTSCKKKQ 652
Cdd:pfam08604  398 KAQKQPPSTSGSPAFTFSSPIVKSTEASVPPPsPSIGFTFSVPVAKTAELSGSSGT--SVVSVVSTETTTVNSTSNKKEE 475

                          490       500       510
                   ....*....|....*....|....*....|..
gi 742160602   653 DEDCESPFRVAKTLKEGSVLDVLKSPGFASSK 684
Cdd:pfam08604  476 EEEFEGPFKPAKVLKQGSVLDILKSPGFASPK 507
Nup_retrotrp_bd pfam10599
Retro-transposon transporting motif; This is the highly conserved C-terminal motif ...
 1455-1542 3.24e-19

Retro-transposon transporting motif; This is the highly conserved C-terminal motif GRKIxxxxxRRKx of nucleoporins that plays a critical and unique role in the nuclear import of retro-transposons in both yeasts and higher organizms. It would appear that the arginine residues at positions 2 and 9-10 constitute a bipartite nuclear localization signal, with two basic peptide motifs separated by an interchangeable spacer sequence, that is crucial for the retro-transposon activity.


Pssm-ID: 371156  Cd Length: 86  Bit Score: 83.57  E-value: 3.24e-19
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1455 PNPSSVFQFGSSTaTNFNFTNSSPSGVFTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMfsssgPSVSGRKI 1534
Cdd:pfam10599    5 PDPASVFGFGSSN-TNFNFTNNNPSTPFGFGASPSTPQAANPPSAFTPPAFSQSPASFNVGSNGSNM-----FSVSGRKI 78


                   ....*...
gi 742160602  1535 KTAVRRKK 1542
Cdd:pfam10599   79 AQMRRRRR 86
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
787-815 2.14e-09

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 53.90  E-value: 2.14e-09
                           10        20
                   ....*....|....*....|....*....
gi 742160602   787 VGTWDCDTCLVQNKPEAIKCVACETPKPG 815
Cdd:pfam00641    2 EGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
857-886 8.73e-09

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 52.35  E-value: 8.73e-09
                           10        20        30
                   ....*....|....*....|....*....|
gi 742160602   857 PVGSWECPVCCVSNNAEDNKCVSCMSEKPG 886
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKPD 30
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
916-944 3.14e-08

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 50.81  E-value: 3.14e-08
                           10        20
                   ....*....|....*....|....*....
gi 742160602   916 PEGSWNCEVCLVQNKADSTKCIACETVKS 944
Cdd:pfam00641    1 REGDWDCSKCLVQNFATSTKCVACQAPKP 29
zf-RanBP pfam00641
Zn-finger in Ran binding protein and others;
724-750 3.33e-07

Zn-finger in Ran binding protein and others;


Pssm-ID: 395516 [Multi-domain]  Cd Length: 30  Bit Score: 47.73  E-value: 3.33e-07
                           10        20
                   ....*....|....*....|....*..
gi 742160602   724 SWQCDTCLLQNKVTDNKCVACQATKLL 750
Cdd:pfam00641    4 DWDCSKCLVQNFATSTKCVACQAPKPD 30
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 918-942 2.35e-06

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 45.39  E-value: 2.35e-06
                            10        20
                    ....*....|....*....|....*
gi 742160602    918 GSWNCEVCLVQNKADSTKCIACETV 942
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGAP 25
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 788-812 7.09e-06

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 43.85  E-value: 7.09e-06
                            10        20
                    ....*....|....*....|....*
gi 742160602    788 GTWDCDTCLVQNKPEAIKCVACETP 812
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGAP 25
PPE COG5651
PPE-repeat protein [Function unknown];
1284-1494 2.87e-05

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 48.35  E-value: 2.87e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1284 SPSAPVAAFVFGqASNPVSSSAFANAAESSTSQSLLFSQESKPATTSSTGTAVTPFVFGTGASSNNTATSGFNFGATTTS 1363
Cdd:COG5651   176 NPGGLLGAQNAG-SGNTSSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFAGTGAAAGAAAAAAAAAAAAGAG 254

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1364 SSAGSSFVFGTGASAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPPTFGTVSSSGQPPVFGQQ 1443
Cdd:COG5651   255 ASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGAAGATGAGAALGAGAAA 334

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 742160602 1444 PGQSAFGSGTAPNPSSVFQFGSSTATNFNFTNSSPSGVFTFGASPSTPAAS 1494
Cdd:COG5651   335 AAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 1320-1509 6.05e-05

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 47.74  E-value: 6.05e-05
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1320 FSQESKPATTSSTGTavtPFVFGTGASSNNTATSGFNFGATTTSSSAGSS--------------------FVFGTGASAp 1379
Cdd:pfam15967    4 FSFGGGPGSTATAGG---GFSFGAAAASNPGSTGGFSFGTLGAAPAATATtttatlglggglfgqkpatgFTFGTPASS- 79

                           90       100       110       120       130       140       150       160
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1380 SASPAFGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPP---TFGTVSSSGQPpvfgqQPGQSAF--GSGTA 1454
Cdd:pfam15967   80 TAATGPTGLTLGTPAATTAASTGFSLGFNKPAASATPFSLPASSTSGgglSLGSVLTSTAA-----QQGATGFtlNLGGT 154

                          170       180       190       200       210       220
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742160602  1455 PNPSSVFQFGSSTATNFN------FTNSSPSGV------FTFGASPSTPAASSQPS-GSGGFQFSQSS 1509
Cdd:pfam15967  155 PATTTAVSTGLSLGSTLTslggslFQNTNSTGLgqttlgLTLLATSTAPVSAPAASeGLGGLDFSTSS 222
PPE COG5651
PPE-repeat protein [Function unknown];
1231-1457 6.55e-05

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 47.20  E-value: 6.55e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1231 QPAKPAFAFGAQTSTAADQgvakpvfNFLNSSSSNSSAPAASVGGGIFGSSTSSPSAPVAAFVFGQAsNPVSSSAFANAA 1310
Cdd:COG5651   173 TITNPGGLLGAQNAGSGNT-------SSNPGFANLGLTGLNQVGIGGLNSGSGPIGLNSGPGNTGFA-GTGAAAGAAAAA 244

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1311 ESSTSQSLLfsqeskPATTSSTGTAVTPFVFGTGASSNNTATSGFNFGATTTSSSAGSSFVFGTGASAPSASPAFGANQT 1390
Cdd:COG5651   245 AAAAAAAGA------GASAALASLAATLLNASSLGLAATAASSAATNLGLAGSPLGLAGGGAGAAAATGLGLGAGGAAGA 318

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 742160602 1391 PTFGQSQGASQPNPPGFGSISSSGALFSAGSQPAPPTFGTVSSSGQPPVFGQQPGQSAFGSGTAPNP 1457
Cdd:COG5651   319 AGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGGGGALGAGGGGGSAGAAAGAASGGGAAA 385
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 723-746 2.91e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 39.22  E-value: 2.91e-04
                            10        20
                    ....*....|....*....|....
gi 742160602    723 SSWQCDTCLLQNKVTDNKCVACQA 746
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFACGA 24
ZnF_RBZ smart00547
Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. ...
 859-880 5.73e-04

Zinc finger domain; Zinc finger domain in Ran-binding proteins (RanBPs), and other proteins. In RanBPs, this domain binds RanGDP.


Pssm-ID: 197784 [Multi-domain]  Cd Length: 25  Bit Score: 38.45  E-value: 5.73e-04
                            10        20
                    ....*....|....*....|..
gi 742160602    859 GSWECPVCCVSNNAEDNKCVSC 880
Cdd:smart00547    1 GDWECPACTFLNFASRSKCFAC 22
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
1279-1483 9.82e-04

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 43.59  E-value: 9.82e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1279 GSSTSSPSAPVAAFVFGQASNPVSSSAFANAAESSTSQSLLFSQESKPATTSSTGTAVTpfvfgTGASSNNTATSGFNFG 1358
Cdd:COG3469    23 LGAAATAASVTLTAATATTVVSTTGSVVVAASGSAGSGTGTTAASSTAATSSTTSTTAT-----ATAAAAAATSTSATLV 97

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1359 ATTTSSSAGSSFVFGTGASAPSASPAFGANQTPTFGQSQGASQPNPPGFGS--ISSSGALFSAGSQPAPPTFGTVSSSGQ 1436
Cdd:COG3469    98 ATSTASGANTGTSTVTTTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTttTTVSGTETATGGTTTTSTTTTTTSAST 177

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*..
gi 742160602 1437 PPVFGQQPGQSAFGSGTAPNPSsvfqfgSSTATNFNFTNSSPSGVFT 1483
Cdd:COG3469   178 TPSATTTATATTASGATTPSAT------TTATTTGPPTPGLPKHVLV 218
KREPA2 cd23959
Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of ...
 1277-1497 2.15e-03

Kinetoplastid RNA Editing Protein A2 (KREPA2); The KREPA2 (TbMP63) protein is a component of the parasitic protozoan's KREPA RNA editing catalytic complex (RECC). Kinetoplastid RNA editing (KRE) proteins occur as pairs or sets of related proteins in multiple complexes. KREPA complex is composed of six components (KREPA1-6), which share a conserved C-terminal region containing an oligonucleotide-binding (OB)-fold-like domain. KREPAs are responsible for the site-specific insertion and deletion of U nucleotides in the kinetoplastid mitochondria pre-messenger RNA. Apart from the conserved C-terminal OB-fold domain, KREPA1, KREPA2, and KREPA3 contain two conserved C2H2 zinc-finger domains. KREPA2 and kinetoplastid RNA editing ligase 1 (KREL1) are specific for ligation post-U-deletion and are paralogous to KREL2 and KREPA1 that are specific for ligation post-U-insertion. KREPA2, is critical for RECC stability and KREL1 integration into the complex.


Pssm-ID: 467780 [Multi-domain]  Cd Length: 424  Bit Score: 42.55  E-value: 2.15e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1277 IFGSSTSSPSAPVAAFVFGQASNPVSSSAFANAAESSTSQ-------SLLFSQESKPATTSSTGTavtpfvFGTGASSNN 1349
Cdd:cd23959    45 VFAARPSDQEEPLYGAVSPEGENPFDGPGLVTASTVSDCYvgnanfyEVDMSDAFAMAPDESLGP------FRAARVPNP 118

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1350 TATSGFNFGATTTSSSAGSSFVfgtgasAPSASPAFGANQTPTFGQSQGASQPNPPGFGSISSSgalFSAGSQPAPPTFG 1429
Cdd:cd23959   119 FSASSSTQRETHKTAQVAPPKA------EPQTAPVTPFGQLPMFGQHPPPAKPLPAAAAAQQSS---ASPGEVASPFASG 189

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 742160602 1430 TVSSsgqppvfgqqpgqSAFGSGTAPNPSSVFQFGSSTATNFNFTNSSPSGVFTFGASPSTPAASSQP 1497
Cdd:cd23959   190 TVSA-------------SPFATATDTAPSSGAPDGFPAEASAPSPFAAPASAASFPAAPVANGEAATP 244
PPE COG5651
PPE-repeat protein [Function unknown];
1327-1532 4.18e-03

PPE-repeat protein [Function unknown];


Pssm-ID: 444372 [Multi-domain]  Cd Length: 385  Bit Score: 41.42  E-value: 4.18e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1327 ATTSSTGTAVTPFvfgTGASSNNTATSGFNFGATTTSSSAGSSFVFGTGASAPSASPAFGANQTPtfgqSQGASQPNPPG 1406
Cdd:COG5651   155 AAASAAAVALTPF---TQPPPTITNPGGLLGAQNAGSGNTSSNPGFANLGLTGLNQVGIGGLNSG----SGPIGLNSGPG 227

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1407 FGSISSSG--ALFSAGSQPAPPTFGTVSSSGQPPVFGQQPGQSAFGSGTAPNPSSVFQFG---SSTATNFNFTNSSPSGV 1481
Cdd:COG5651   228 NTGFAGTGaaAGAAAAAAAAAAAAGAGASAALASLAATLLNASSLGLAATAASSAATNLGlagSPLGLAGGGAGAAAATG 307

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|.
gi 742160602 1482 FTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMFSSSGPSVSGR 1532
Cdd:COG5651   308 LGLGAGGAAGAAGATGAGAALGAGAAAAAAGAAAGAGAAAAAAAGGAGGGG 358
Nucleoporin_FG2 pfam15967
Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of ...
 1400-1497 7.42e-03

Nucleoporin FG repeated region; Nucleoporin_FG2, or nucleoporin p58/p45, is a family of chordate nucleoporins. The proteins carry many repeats of the FG sequence motif.


Pssm-ID: 435043 [Multi-domain]  Cd Length: 586  Bit Score: 40.81  E-value: 7.42e-03
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602  1400 SQPNPPGFGSISSSGALFSAgsqPAPPTFGTVSSSGQPPVFGQQPGQSAFGSGTAPNPSSVF---QFGSSTATNFNFTNS 1476
Cdd:pfam15967  469 TQQQQPTTGTQPSLGVSFGA---PFASGIGTGLFGSGPGFGSVTSGGSSFGFGSTSKPSGGSlsaGFGSSSTSGFNFSNP 545

                           90       100
                   ....*....|....*....|....*
gi 742160602  1477 --SPSGVFTFGAS--PSTPAASSQP 1497
Cdd:pfam15967  546 giNASAGLTFGVSnpPATGFGTGGQ 570
ser_rich_anae_1 NF033849
serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 ...
 1307-1530 8.48e-03

serine-rich protein; This serine-rich protein belongs to a family with large size (over 1000 amino acids), which a highly serine-rich central region that averages over 300 aa in length. Species encoding members of this family of proteins tend to be anaerobic bacteria, including Gram-positive bacteria of the human gut microbiome and Chloroflexi from marine sediments.


Pssm-ID: 468206 [Multi-domain]  Cd Length: 1122  Bit Score: 40.76  E-value: 8.48e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1307 ANAAES-STSQSLLFSQESKPATTSSTGTAVTpfvFGTGASSNNTATSGFNfgatttsSSAGSSFVFGTGASAP-SASPA 1384
Cdd:NF033849  233 ANLGQSaGTGYGESVGHSTSQGQSHSVGTSES---HSVGTSQSQSHTTGHG-------STRGWSHTQSTSESEStGQSSS 302

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1385 FGANQTPTFGQSQGASQPNPPGFGSISSSGALFSAGsqpappTFGTVSSSGQPPVFGQQPGQSAFGSGTAPNPSSVFQFG 1464
Cdd:NF033849  303 VGTSESQSHGTTEGTSTTDSSSHSQSSSYNVSSGTG------VSSSHSDGTSQSTSISHSESSSESTGTSVGHSTSSSVS 376

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 742160602 1465 SSTATNFNFTNSS---------PSGVFTFGASPSTPAASSQPSGSGGFQFSQSSAAFTVGSNGKNMFSSSGPSVS 1530
Cdd:NF033849  377 SSESSSRSSSSGVsggfsggiaGGGVTSEGLGASQGGSEGWGSGDSVQSVSQSYGSSSSTGTSSGHSDSSSHSTS 451
Chi1 COG3469
Chitinase [Carbohydrate transport and metabolism];
1240-1437 9.94e-03

Chitinase [Carbohydrate transport and metabolism];


Pssm-ID: 442692 [Multi-domain]  Cd Length: 534  Bit Score: 40.51  E-value: 9.94e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1240 GAQTSTAADQGVAKPVF-NFLNSSSSNSSAPAASVGGGIFGSSTSSPSAPV--AAFVFGQASNPVSSSAFANAAESSTSQ 1316
Cdd:COG3469    12 AGGASATAVTLLGAAATaASVTLTAATATTVVSTTGSVVVAASGSAGSGTGttAASSTAATSSTTSTTATATAAAAAATS 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 742160602 1317 SLLFSQESKPATTSSTGTAVTPfVFGTGASSNNTATSGFNFGATTTSSSAGSSFVFGTGASAPSASPAF--GANQTPTFG 1394
Cdd:COG3469    92 TSATLVATSTASGANTGTSTVT-TTSTGAGSVTSTTSSTAGSTTTSGASATSSAGSTTTTTTVSGTETAtgGTTTTSTTT 170

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|...
gi 742160602 1395 QSQGASQPNPPGFGSISSSGALFSAGSQPAPPTFGTVSSSGQP 1437
Cdd:COG3469   171 TTTSASTTPSATTTATATTASGATTPSATTTATTTGPPTPGLP 213
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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