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Conserved domains on  [gi|740772988|ref|WP_038558272|]
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putative hydro-lyase [Terribacillus goriensis]

Protein Classification

putative hydro-lyase( domain architecture ID 10008506)

putative hydro-lyase belonging to the D-glutamate cyclase family (formerly called DUF1445); similar to Pseudomonas aeruginosa putative hydro-lyase PA2116

EC:  4.2.1.-
Gene Ontology:  GO:0016836

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
YcsI COG4336
Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];
1-253 3.97e-172

Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];


:

Pssm-ID: 443477  Cd Length: 265  Bit Score: 475.05  E-value: 3.97e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988   1 MNPSTIREKIRSGEHNTHTSGLGSDYVQANLVIVPKEYAFDFLLFANRNPKSCPIIDVLEPGVVE-SALATGSDIRSDIP 79
Cdd:COG4336    9 MSPAEARAAIRAGEFTGPTAGLAPGYVQANLVILPKDWAYDFLLFCQRNPKPCPLLDVTEPGSPElPALGPDADIRTDLP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  80 LYFVYENGKLTEKRQDLKEIWRDDFVSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMR 159
Cdd:COG4336   89 RYRVYRDGELVEEVTDITDLWRDDLVTFLIGCSFSFEEALLAAGIPVRHIEEGRNVPMYRTNIPCRPAGRFSGPMVVSMR 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988 160 PIKNELVQKAIDVTAQFPNMHGSPIHVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHA 239
Cdd:COG4336  169 PIPAADVIRAVQITSRFPAVHGAPVHIGDPAAIGIADLAKPDFGDAVEIRPGEVPVFWACGVTPQAAIMAAKPPFAITHA 248
                        250
                 ....*....|....
gi 740772988 240 PGHMFITDVTNDEF 253
Cdd:COG4336  249 PGHMLITDVPDSEL 262
 
Name Accession Description Interval E-value
YcsI COG4336
Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];
1-253 3.97e-172

Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];


Pssm-ID: 443477  Cd Length: 265  Bit Score: 475.05  E-value: 3.97e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988   1 MNPSTIREKIRSGEHNTHTSGLGSDYVQANLVIVPKEYAFDFLLFANRNPKSCPIIDVLEPGVVE-SALATGSDIRSDIP 79
Cdd:COG4336    9 MSPAEARAAIRAGEFTGPTAGLAPGYVQANLVILPKDWAYDFLLFCQRNPKPCPLLDVTEPGSPElPALGPDADIRTDLP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  80 LYFVYENGKLTEKRQDLKEIWRDDFVSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMR 159
Cdd:COG4336   89 RYRVYRDGELVEEVTDITDLWRDDLVTFLIGCSFSFEEALLAAGIPVRHIEEGRNVPMYRTNIPCRPAGRFSGPMVVSMR 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988 160 PIKNELVQKAIDVTAQFPNMHGSPIHVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHA 239
Cdd:COG4336  169 PIPAADVIRAVQITSRFPAVHGAPVHIGDPAAIGIADLAKPDFGDAVEIRPGEVPVFWACGVTPQAAIMAAKPPFAITHA 248
                        250
                 ....*....|....
gi 740772988 240 PGHMFITDVTNDEF 253
Cdd:COG4336  249 PGHMLITDVPDSEL 262
PRK05463 PRK05463
putative hydro-lyase;
1-253 4.21e-164

putative hydro-lyase;


Pssm-ID: 180100  Cd Length: 262  Bit Score: 454.67  E-value: 4.21e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988   1 MNPSTIREKIRSGEHNTHTSGLGSDYVQANLVIVPKEYAFDFLLFANRNPKSCPIIDVLEPGVVE-SALATGSDIRSDIP 79
Cdd:PRK05463   6 MTPAEARQAIRAGELTGPTAGLAPGYAQANLVILPKDWAYDFLLFCQRNPKPCPLLDVTEPGSPElPLLGPDADIRTDVP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  80 LYFVYENGKLTEKRQDLKEIWRDDFVSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMR 159
Cdd:PRK05463  86 RYRVYRDGELVEEVTDITDLWRDDLVTFLIGCSFSFEHALLEAGIPVRHIEEGRNVPMYRTNIPCRPAGRFSGPMVVSMR 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988 160 PIKNELVQKAIDVTAQFPNMHGSPIHVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHA 239
Cdd:PRK05463 166 PIPAADAIRAVQITSRFPAVHGAPVHIGDPAAIGIADLARPDFGDAVEIEPGEIPVFWACGVTPQAVVMAAKPPFAITHA 245
                        250
                 ....*....|....
gi 740772988 240 PGHMFITDVTNDEF 253
Cdd:PRK05463 246 PGHMLITDLPDSEL 259
D-Glu_cyclase pfam07286
D-glutamate cyclase; This family includes mitochondrial D-glutamate cyclase which converts ...
105-247 3.06e-93

D-glutamate cyclase; This family includes mitochondrial D-glutamate cyclase which converts D-glutamate to 5-oxo-D-proline. This family also includes numerous uncharacterized proteins from bacteria.


Pssm-ID: 462133  Cd Length: 143  Bit Score: 270.48  E-value: 3.06e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  105 VSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMRPIKNELVQKAIDVTAQFPNMHGSPI 184
Cdd:pfam07286   1 VTFLIGCSFSFEEALLEAGIPVRHIEQGRNVPMYRTNIPCCPAGPFSGPMVVSMRPIPKDKVERAVQITSRFPAVHGAPV 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 740772988  185 HVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHAPGHMFITD 247
Cdd:pfam07286  81 HIGDPALIGIKDLSKPDYGDPVEIQPGEVPVFWACGVTPQEAVMSAKPPLAITHAPGHMFVTD 143
 
Name Accession Description Interval E-value
YcsI COG4336
Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];
1-253 3.97e-172

Uncharacterized conserved protein YcsI, UPF0317/DUF1446 family [Function unknown];


Pssm-ID: 443477  Cd Length: 265  Bit Score: 475.05  E-value: 3.97e-172
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988   1 MNPSTIREKIRSGEHNTHTSGLGSDYVQANLVIVPKEYAFDFLLFANRNPKSCPIIDVLEPGVVE-SALATGSDIRSDIP 79
Cdd:COG4336    9 MSPAEARAAIRAGEFTGPTAGLAPGYVQANLVILPKDWAYDFLLFCQRNPKPCPLLDVTEPGSPElPALGPDADIRTDLP 88
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  80 LYFVYENGKLTEKRQDLKEIWRDDFVSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMR 159
Cdd:COG4336   89 RYRVYRDGELVEEVTDITDLWRDDLVTFLIGCSFSFEEALLAAGIPVRHIEEGRNVPMYRTNIPCRPAGRFSGPMVVSMR 168
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988 160 PIKNELVQKAIDVTAQFPNMHGSPIHVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHA 239
Cdd:COG4336  169 PIPAADVIRAVQITSRFPAVHGAPVHIGDPAAIGIADLAKPDFGDAVEIRPGEVPVFWACGVTPQAAIMAAKPPFAITHA 248
                        250
                 ....*....|....
gi 740772988 240 PGHMFITDVTNDEF 253
Cdd:COG4336  249 PGHMLITDVPDSEL 262
PRK05463 PRK05463
putative hydro-lyase;
1-253 4.21e-164

putative hydro-lyase;


Pssm-ID: 180100  Cd Length: 262  Bit Score: 454.67  E-value: 4.21e-164
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988   1 MNPSTIREKIRSGEHNTHTSGLGSDYVQANLVIVPKEYAFDFLLFANRNPKSCPIIDVLEPGVVE-SALATGSDIRSDIP 79
Cdd:PRK05463   6 MTPAEARQAIRAGELTGPTAGLAPGYAQANLVILPKDWAYDFLLFCQRNPKPCPLLDVTEPGSPElPLLGPDADIRTDVP 85
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  80 LYFVYENGKLTEKRQDLKEIWRDDFVSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMR 159
Cdd:PRK05463  86 RYRVYRDGELVEEVTDITDLWRDDLVTFLIGCSFSFEHALLEAGIPVRHIEEGRNVPMYRTNIPCRPAGRFSGPMVVSMR 165
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988 160 PIKNELVQKAIDVTAQFPNMHGSPIHVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHA 239
Cdd:PRK05463 166 PIPAADAIRAVQITSRFPAVHGAPVHIGDPAAIGIADLARPDFGDAVEIEPGEIPVFWACGVTPQAVVMAAKPPFAITHA 245
                        250
                 ....*....|....
gi 740772988 240 PGHMFITDVTNDEF 253
Cdd:PRK05463 246 PGHMLITDLPDSEL 259
D-Glu_cyclase pfam07286
D-glutamate cyclase; This family includes mitochondrial D-glutamate cyclase which converts ...
105-247 3.06e-93

D-glutamate cyclase; This family includes mitochondrial D-glutamate cyclase which converts D-glutamate to 5-oxo-D-proline. This family also includes numerous uncharacterized proteins from bacteria.


Pssm-ID: 462133  Cd Length: 143  Bit Score: 270.48  E-value: 3.06e-93
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 740772988  105 VSFLIGCSFTFESALLKEGVPLKHIEQNRNVAMYITNRQTKQAGEFSGPVVVSMRPIKNELVQKAIDVTAQFPNMHGSPI 184
Cdd:pfam07286   1 VTFLIGCSFSFEEALLEAGIPVRHIEQGRNVPMYRTNIPCCPAGPFSGPMVVSMRPIPKDKVERAVQITSRFPAVHGAPV 80
                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 740772988  185 HVGDPKEIGIDDISEPDFGEFTEFGEGETPVFWECGVTPQSAAIHSQIPFVITHAPGHMFITD 247
Cdd:pfam07286  81 HIGDPALIGIKDLSKPDYGDPVEIQPGEVPVFWACGVTPQEAVMSAKPPLAITHAPGHMFVTD 143
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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