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Conserved domains on  [gi|739666855|ref|WP_037522130|]
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prolyl oligopeptidase family serine peptidase [Sphingobium yanoikuyae]

Protein Classification

S9 family peptidase( domain architecture ID 13559775)

peptidase S9 family protein, an oligopeptidase which may cleave the prolyl bond of short peptides, similar to oligopeptidase B, which cleaves on the C-terminal side of lysyl and argininyl residues

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
506-752 2.05e-40

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


:

Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 148.63  E-value: 2.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 506 AADGVTkTYGLLFKPlgyESGTRYPLIDLIYGGPQVHNVPHSSFASgdigggtyvdavHLASLGAYVLILDGRGTANREQ 585
Cdd:COG1506    4 SADGTT-LPGWLYLP---ADGKKYPVVVYVHGGPGSRDDSFLPLAQ------------ALASRGYAVLAPDYRGYGESAG 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 586 DFRTAsyraahtasNLEDHVAAIRQLAQHnDQIDLDRVGITGFSGGGYMTAHAALRFGDFFKVAVAGGGNYDQALFWHS- 664
Cdd:COG1506   68 DWGGD---------EVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTt 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 665 --WGERYHGAY--DAEHYAAQAAKTYAEGLTGKLMLVHGMLDHGCHPAGLFQLVQSLIDADKDVDLVLLPRGGHDWLGYG 740
Cdd:COG1506  138 reYTERLMGGPweDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAG 217

                        250
                 ....*....|....*.
gi 739666855 741 ----MRRRWAYFVSHL 752
Cdd:COG1506  218 apdyLERILDFLDRHL 233
DPPIV_N super family cl37636
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 101-471 6.37e-32

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


The actual alignment was detected with superfamily member pfam00930:

Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 127.82  E-value: 6.37e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  101 FSAYGEAYAYDWSAQALTTTDRK----ADANWlaSPDGASALLVAGDDLRLRDLSTGDERALTTDGTPEYAYAVPpvalr 176
Cdd:pfam00930  19 HSYTADYYIYDLETNRVEPLPPGegkiQDAKW--SPDGDRLAFVRDNNLYVRELATGKEIQITSDGSDGIFNGVA----- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  177 klNQVRGVEV---PEAL-WSPDGQWILTLQTDERHVPDLSLAEYAPvSGVRPVIHSNRTSLPEDPKVT-EFRMiaIEVAT 251
Cdd:pfam00930  92 --DWVYEEEVlgsNSAVwWSPDGSRLAFLRFDESEVPIITLPYYTD-EGPGPEVREIKYPKAGAPNPTvELFV--YDLAS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  252 GRQVEARYPrlGAVRMNATVFgaGMAWWSADSRTgYFVDIERGEQKVHVVAFDVATGSTRTVFSEESASYVEVSVNVYTK 331
Cdd:pfam00930 167 GKTVEVVPP--DDLSDADYYI--TRVKWVPDGKL-LVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFI 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  332 aliapLPATNELVWYSERSGRGHLYLYDLATGSLRgAITQGDWQVRDVLRIDPVRREVFLLAAGiagaenpyvtkpcvas 411
Cdd:pfam00930 242 -----KRDGSGFLWISERDGYNHLYLYDLDGKSPI-QLTSGNWEVTSILGVDETRDLVYFTATE---------------- 299

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 739666855  412 ldgcvrvlsDMPGDHAVWR-----PGSIA--TMMKVMEGMDPEtisgLSPTGDYFVETVSTVaDLPR 471
Cdd:pfam00930 300 ---------DSPTERHLYSvsldsGGEPTclTDDSGDHDYSAS----FSPNGSYYVLTYSGP-DTPP 352
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
506-752 2.05e-40

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 148.63  E-value: 2.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 506 AADGVTkTYGLLFKPlgyESGTRYPLIDLIYGGPQVHNVPHSSFASgdigggtyvdavHLASLGAYVLILDGRGTANREQ 585
Cdd:COG1506    4 SADGTT-LPGWLYLP---ADGKKYPVVVYVHGGPGSRDDSFLPLAQ------------ALASRGYAVLAPDYRGYGESAG 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 586 DFRTAsyraahtasNLEDHVAAIRQLAQHnDQIDLDRVGITGFSGGGYMTAHAALRFGDFFKVAVAGGGNYDQALFWHS- 664
Cdd:COG1506   68 DWGGD---------EVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTt 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 665 --WGERYHGAY--DAEHYAAQAAKTYAEGLTGKLMLVHGMLDHGCHPAGLFQLVQSLIDADKDVDLVLLPRGGHDWLGYG 740
Cdd:COG1506  138 reYTERLMGGPweDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAG 217

                        250
                 ....*....|....*.
gi 739666855 741 ----MRRRWAYFVSHL 752
Cdd:COG1506  218 apdyLERILDFLDRHL 233
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
565-752 2.55e-32

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 124.65  E-value: 2.55e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  565 LASLGAYVLILDGRGTANREQDFRTASYRaaHTASN-LEDHVAAIRQLAQHNdQIDLDRVGITGFSGGGYMTAHAALRFG 643
Cdd:pfam00326  10 LADRGYVVAIANGRGSGGYGEAFHDAGKG--DLGQNeFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAALNQRP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  644 DFFKVAVAGGGNYDqALFWHS-----WGERY--HGA--YDAEHYAAQAAKTYAE--GLTGKLMLVHGMLDHGCHPAGLFQ 712
Cdd:pfam00326  87 DLFKAAVAHVPVVD-WLAYMSdtslpFTERYmeWGNpwDNEEGYDYLSPYSPADnvKVYPPLLLIHGLLDDRVPPWQSLK 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 739666855  713 LVQSLIDADKDVDLVLLPRGGHdWLGYG------MRRRWAYFVSHL 752
Cdd:pfam00326 166 LVAALQRKGVPFLLLIFPDEGH-GIGKPrnkveeYARELAFLLEYL 210
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 101-471 6.37e-32

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 127.82  E-value: 6.37e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  101 FSAYGEAYAYDWSAQALTTTDRK----ADANWlaSPDGASALLVAGDDLRLRDLSTGDERALTTDGTPEYAYAVPpvalr 176
Cdd:pfam00930  19 HSYTADYYIYDLETNRVEPLPPGegkiQDAKW--SPDGDRLAFVRDNNLYVRELATGKEIQITSDGSDGIFNGVA----- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  177 klNQVRGVEV---PEAL-WSPDGQWILTLQTDERHVPDLSLAEYAPvSGVRPVIHSNRTSLPEDPKVT-EFRMiaIEVAT 251
Cdd:pfam00930  92 --DWVYEEEVlgsNSAVwWSPDGSRLAFLRFDESEVPIITLPYYTD-EGPGPEVREIKYPKAGAPNPTvELFV--YDLAS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  252 GRQVEARYPrlGAVRMNATVFgaGMAWWSADSRTgYFVDIERGEQKVHVVAFDVATGSTRTVFSEESASYVEVSVNVYTK 331
Cdd:pfam00930 167 GKTVEVVPP--DDLSDADYYI--TRVKWVPDGKL-LVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFI 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  332 aliapLPATNELVWYSERSGRGHLYLYDLATGSLRgAITQGDWQVRDVLRIDPVRREVFLLAAGiagaenpyvtkpcvas 411
Cdd:pfam00930 242 -----KRDGSGFLWISERDGYNHLYLYDLDGKSPI-QLTSGNWEVTSILGVDETRDLVYFTATE---------------- 299

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 739666855  412 ldgcvrvlsDMPGDHAVWR-----PGSIA--TMMKVMEGMDPEtisgLSPTGDYFVETVSTVaDLPR 471
Cdd:pfam00930 300 ---------DSPTERHLYSvsldsGGEPTclTDDSGDHDYSAS----FSPNGSYYVLTYSGP-DTPP 352
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 592-659 3.61e-04

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 42.47  E-value: 3.61e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 739666855  592 YRAAHTASNlEDHVAAIRQLAQH---NDQIDLDRVGITGFSGGGYMTAHAALRFGDFFK-VAVAGGGNYDQA 659
Cdd:TIGR01840  64 FFTHHRARG-TGEVESLHQLIDAvkaNYSIDPNRVYVTGLSAGGGMTAVLGCTYPDVFAgGASNAGLPYGEA 134
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 279-372 8.58e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 37.73  E-value: 8.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 279 WSADSRTGYFVDIERGEQKVHVVafDVATGSTRTVfSEESASYVEVSVNvytkaliaplPATNELVWYSERSGRGHLYLY 358
Cdd:COG0823   38 WSPDGRRIAFTSDRGGGPQIYVV--DADGGEPRRL-TFGGGYNASPSWS----------PDGKRLAFVSRSDGRFDIYVL 104

                         90
                 ....*....|....
gi 739666855 359 DLATGSLRgAITQG 372
Cdd:COG0823  105 DLDGGAPR-RLTDG 117
 
Name Accession Description Interval E-value
DAP2 COG1506
Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];
506-752 2.05e-40

Dipeptidyl aminopeptidase/acylaminoacyl peptidase [Amino acid transport and metabolism];


Pssm-ID: 441115 [Multi-domain]  Cd Length: 234  Bit Score: 148.63  E-value: 2.05e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 506 AADGVTkTYGLLFKPlgyESGTRYPLIDLIYGGPQVHNVPHSSFASgdigggtyvdavHLASLGAYVLILDGRGTANREQ 585
Cdd:COG1506    4 SADGTT-LPGWLYLP---ADGKKYPVVVYVHGGPGSRDDSFLPLAQ------------ALASRGYAVLAPDYRGYGESAG 67

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 586 DFRTAsyraahtasNLEDHVAAIRQLAQHnDQIDLDRVGITGFSGGGYMTAHAALRFGDFFKVAVAGGGNYDQALFWHS- 664
Cdd:COG1506   68 DWGGD---------EVDDVLAAIDYLAAR-PYVDPDRIGIYGHSYGGYMALLAAARHPDRFKAAVALAGVSDLRSYYGTt 137

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 665 --WGERYHGAY--DAEHYAAQAAKTYAEGLTGKLMLVHGMLDHGCHPAGLFQLVQSLIDADKDVDLVLLPRGGHDWLGYG 740
Cdd:COG1506  138 reYTERLMGGPweDPEAYAARSPLAYADKLKTPLLLIHGEADDRVPPEQAERLYEALKKAGKPVELLVYPGEGHGFSGAG 217

                        250
                 ....*....|....*.
gi 739666855 741 ----MRRRWAYFVSHL 752
Cdd:COG1506  218 apdyLERILDFLDRHL 233
Peptidase_S9 pfam00326
Prolyl oligopeptidase family;
565-752 2.55e-32

Prolyl oligopeptidase family;


Pssm-ID: 459761 [Multi-domain]  Cd Length: 213  Bit Score: 124.65  E-value: 2.55e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  565 LASLGAYVLILDGRGTANREQDFRTASYRaaHTASN-LEDHVAAIRQLAQHNdQIDLDRVGITGFSGGGYMTAHAALRFG 643
Cdd:pfam00326  10 LADRGYVVAIANGRGSGGYGEAFHDAGKG--DLGQNeFDDFIAAAEYLIEQG-YTDPDRLAIWGGSYGGYLTGAALNQRP 86

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  644 DFFKVAVAGGGNYDqALFWHS-----WGERY--HGA--YDAEHYAAQAAKTYAE--GLTGKLMLVHGMLDHGCHPAGLFQ 712
Cdd:pfam00326  87 DLFKAAVAHVPVVD-WLAYMSdtslpFTERYmeWGNpwDNEEGYDYLSPYSPADnvKVYPPLLLIHGLLDDRVPPWQSLK 165

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|....*.
gi 739666855  713 LVQSLIDADKDVDLVLLPRGGHdWLGYG------MRRRWAYFVSHL 752
Cdd:pfam00326 166 LVAALQRKGVPFLLLIFPDEGH-GIGKPrnkveeYARELAFLLEYL 210
DPPIV_N pfam00930
Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region ...
 101-471 6.37e-32

Dipeptidyl peptidase IV (DPP IV) N-terminal region; This family is an alignment of the region to the N-terminal side of the active site. The Prosite motif does not correspond to this Pfam entry.


Pssm-ID: 395744 [Multi-domain]  Cd Length: 352  Bit Score: 127.82  E-value: 6.37e-32
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  101 FSAYGEAYAYDWSAQALTTTDRK----ADANWlaSPDGASALLVAGDDLRLRDLSTGDERALTTDGTPEYAYAVPpvalr 176
Cdd:pfam00930  19 HSYTADYYIYDLETNRVEPLPPGegkiQDAKW--SPDGDRLAFVRDNNLYVRELATGKEIQITSDGSDGIFNGVA----- 91

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  177 klNQVRGVEV---PEAL-WSPDGQWILTLQTDERHVPDLSLAEYAPvSGVRPVIHSNRTSLPEDPKVT-EFRMiaIEVAT 251
Cdd:pfam00930  92 --DWVYEEEVlgsNSAVwWSPDGSRLAFLRFDESEVPIITLPYYTD-EGPGPEVREIKYPKAGAPNPTvELFV--YDLAS 166

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  252 GRQVEARYPrlGAVRMNATVFgaGMAWWSADSRTgYFVDIERGEQKVHVVAFDVATGSTRTVFSEESASYVEVSVNVYTK 331
Cdd:pfam00930 167 GKTVEVVPP--DDLSDADYYI--TRVKWVPDGKL-LVQWLNRDQNRLKVVLCDAETGRTVVILEETSDGWVELHQDPHFI 241

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  332 aliapLPATNELVWYSERSGRGHLYLYDLATGSLRgAITQGDWQVRDVLRIDPVRREVFLLAAGiagaenpyvtkpcvas 411
Cdd:pfam00930 242 -----KRDGSGFLWISERDGYNHLYLYDLDGKSPI-QLTSGNWEVTSILGVDETRDLVYFTATE---------------- 299

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 739666855  412 ldgcvrvlsDMPGDHAVWR-----PGSIA--TMMKVMEGMDPEtisgLSPTGDYFVETVSTVaDLPR 471
Cdd:pfam00930 300 ---------DSPTERHLYSvsldsGGEPTclTDDSGDHDYSAS----FSPNGSYYVLTYSGP-DTPP 352
COG4099 COG4099
Predicted peptidase [General function prediction only];
506-735 7.23e-14

Predicted peptidase [General function prediction only];


Pssm-ID: 443275 [Multi-domain]  Cd Length: 235  Bit Score: 71.92  E-value: 7.23e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 506 AADGVTKTYgLLFKPLGYESGTRYPLIDLIYGGPQVHNvphssfasgDI------GGGTYVDAVHLASLGAYVLIldgrG 579
Cdd:COG4099   27 PSDGDTLPY-RLYLPKGYDPGKKYPLVLFLHGAGERGT---------DNekqlthGAPKFINPENQAKFPAIVLA----P 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 580 TANREQDFRTASYraahtasnlEDHV-AAIRQLAQHNDqIDLDRVGITGFSGGGYMTAHAALRFGDFFK--VAVAGGGNy 656
Cdd:COG4099   93 QCPEDDYWSDTKA---------LDAVlALLDDLIAEYR-IDPDRIYLTGLSMGGYGTWDLAARYPDLFAaaVPICGGGD- 161

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 739666855 657 dqalfwhswgeryhgaydaEHYAAQAAKTyaegltgKLMLVHGMLDHGCHPAGLFQLVQSLIDADKDVDLVLLPRGGHD 735
Cdd:COG4099  162 -------------------PANAANLKKV-------PVWIFHGAKDDVVPVEESRAMVEALKAAGADVKYTEYPGVGHN 214
DLH COG0412
Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];
562-736 6.67e-13

Dienelactone hydrolase [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 440181 [Multi-domain]  Cd Length: 226  Bit Score: 68.84  E-value: 6.67e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 562 AVHLASLGAYVLILD--GRGTANREQDFRTASYRAAHTASNLEDHVAAIRQLAQHnDQIDLDRVGITGFSGGGYMTAHAA 639
Cdd:COG0412   49 ARRLAAAGYVVLAPDlyGRGGPGDDPDEARALMGALDPELLAADLRAALDWLKAQ-PEVDAGRVGVVGFCFGGGLALLAA 127

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 640 LRFGDfFKVAVAgggnydqalfwhswgerYHGAYDAEHYAAQAAKtyaegLTGKLMLVHGMLDHGCHPAGLFQLVQSLID 719
Cdd:COG0412  128 ARGPD-LAAAVS-----------------FYGGLPADDLLDLAAR-----IKAPVLLLYGEKDPLVPPEQVAALEAALAA 184

                        170
                 ....*....|....*..
gi 739666855 720 ADKDVDLVLLPRGGHDW 736
Cdd:COG0412  185 AGVDVELHVYPGAGHGF 201
Aes COG0657
Acetyl esterase/lipase [Lipid transport and metabolism];
601-740 5.62e-07

Acetyl esterase/lipase [Lipid transport and metabolism];


Pssm-ID: 440422 [Multi-domain]  Cd Length: 207  Bit Score: 51.03  E-value: 5.62e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 601 LEDHVAAIRQLAQHNDQ--IDLDRVGITGFSGGGYMTAHAALRFGDFFKVAVAGggnydQALFWhswgeryhGAYD---- 674
Cdd:COG0657   64 LEDAYAALRWLRANAAElgIDPDRIAVAGDSAGGHLAAALALRARDRGGPRPAA-----QVLIY--------PVLDltas 130

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 739666855 675 -AEHYAAQAAKTYaegltgklmLVHGMLDHGCHPAglFQLVQSLIDADKDVDLVLLPRGGHDWLGYG 740
Cdd:COG0657  131 pLRADLAGLPPTL---------IVTGEADPLVDES--EALAAALRAAGVPVELHVYPGGGHGFGLLA 186
YpfH COG0400
Predicted esterase [General function prediction only];
564-734 9.16e-07

Predicted esterase [General function prediction only];


Pssm-ID: 440169 [Multi-domain]  Cd Length: 200  Bit Score: 50.29  E-value: 9.16e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 564 HLASLGAYVLILDGRGTANREQ------DFRTASYRAAHTASNLEDHVAAIRQLAQHNDqIDLDRVGITGFSGGGYMTAH 637
Cdd:COG0400   27 ELALPGAAVLAPRAPVPEGPGGrawfdlSFLEGREDEEGLAAAAEALAAFIDELEARYG-IDPERIVLAGFSQGAAMALS 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 638 AALRFGDFFKVAVAGGGnydqalfwhswgeRYHGAYDAEHYAAQAAKTyaegltgKLMLVHGMLDHGCHPAGLFQLVQSL 717
Cdd:COG0400  106 LALRRPELLAGVVALSG-------------YLPGEEALPAPEAALAGT-------PVFLAHGTQDPVIPVERAREAAEAL 165

                        170
                 ....*....|....*..
gi 739666855 718 IDADKDVDLVLLPrGGH 734
Cdd:COG0400  166 EAAGADVTYREYP-GGH 181
PldB COG2267
Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];
562-737 1.33e-05

Lysophospholipase, alpha-beta hydrolase superfamily [Lipid transport and metabolism];


Pssm-ID: 441868 [Multi-domain]  Cd Length: 221  Bit Score: 46.92  E-value: 1.33e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 562 AVHLASLGAYVLILDGRGTAnreqdfrtASYRAAHTASNLEDHVAAIRQLAQHNDQIDLDRVGITGFSGGGYMTAHAALR 641
Cdd:COG2267   48 AEALAAAGYAVLAFDLRGHG--------RSDGPRGHVDSFDDYVDDLRAALDALRARPGLPVVLLGHSMGGLIALLYAAR 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 642 FGDFFKVAVAGGGNYDQALFWHSWGERYHGAYDAEHyaaqaaktyAEGLTGKLMLVHGMLDHGCHPAGLFQLVQSLIdad 721
Cdd:COG2267  120 YPDRVAGLVLLAPAYRADPLLGPSARWLRALRLAEA---------LARIDVPVLVLHGGADRVVPPEAARRLAARLS--- 187

                        170
                 ....*....|....*.
gi 739666855 722 KDVDLVLLPRGGHDWL 737
Cdd:COG2267  188 PDVELVLLPGARHELL 203
MenH COG0596
2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, ...
 596-734 4.65e-05

2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold [Coenzyme transport and metabolism, General function prediction only]; 2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate synthase MenH and related esterases, alpha/beta hydrolase fold is part of the Pathway/BioSystem: Menaquinone biosynthesis


Pssm-ID: 440361 [Multi-domain]  Cd Length: 221  Bit Score: 45.38  E-value: 4.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 596 HTASNLEDHVAAIRQLAqhnDQIDLDRVGITGFSGGGYMTAHAALRFGDFFKVAVAGGGNYDQALFWHSWGERYHGAYDA 675
Cdd:COG0596   67 AGGYTLDDLADDLAALL---DALGLERVVLVGHSMGGMVALELAARHPERVAGLVLVDEVLAALAEPLRRPGLAPEALAA 143

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 739666855 676 --EHYAAQAAKTYAEGLTGKLMLVHGMLDHGCHPAGLFQLVQSLidadKDVDLVLLPRGGH 734
Cdd:COG0596  144 llRALARTDLRERLARITVPTLVIWGEKDPIVPPALARRLAELL----PNAELVVLPGAGH 200
LpqC COG3509
Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and ...
 603-659 1.08e-04

Acetyl xylan esterase AxeA and related esterases, LpqC family [Carbohydrate transport and metabolism];


Pssm-ID: 442732 [Multi-domain]  Cd Length: 284  Bit Score: 44.99  E-value: 1.08e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 739666855 603 DHVAAIRQLAQH---NDQIDLDRVGITGFSGGGYMTAHAALRFGDFFK-VAVAGGGNYDQA 659
Cdd:COG3509  113 DDVAFIAALVDDlaaRYGIDPKRVYVTGLSAGGAMAYRLACEYPDVFAaVAPVAGLPYGAA 173
FrsA COG1073
Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms]; ...
 562-734 2.53e-04

Fermentation-respiration switch esterase FrsA, DUF1100 family [Signal transduction mechanisms];


Pssm-ID: 440691 [Multi-domain]  Cd Length: 253  Bit Score: 43.36  E-value: 2.53e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 562 AVHLASLGAYVLILDGRGTANREQDFRTASYRAAHtasnleDHVAAIRQLAQHnDQIDLDRVGITGFSGGGYMTAHAALR 641
Cdd:COG1073   57 AQRLAELGFNVLAFDYRGYGESEGEPREEGSPERR------DARAAVDYLRTL-PGVDPERIGLLGISLGGGYALNAAAT 129

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 642 ---------------FGDFFK--VAVAGGGNYDQALFWH--SWGERYHGAYDAEHYAAQaaktyaegLTGKLMLVHGMLD 702
Cdd:COG1073  130 dprvkavildspftsLEDLAAqrAKEARGAYLPGVPYLPnvRLASLLNDEFDPLAKIEK--------ISRPLLFIHGEKD 201

                        170       180       190
                 ....*....|....*....|....*....|..
gi 739666855 703 HgCHPAGLFQLVQSLIDADKdvDLVLLPRGGH 734
Cdd:COG1073  202 E-AVPFYMSEDLYEAAAEPK--ELLIVPGAGH 230
esterase_phb TIGR01840
esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ...
 592-659 3.61e-04

esterase, PHB depolymerase family; This model describes a subfamily among lipases of the ab-hydrolase family. This subfamily includes bacterial depolymerases for poly(3-hydroxybutyrate) (PHB) and related polyhydroxyalkanoates (PHA), as well as acetyl xylan esterases, feruloyl esterases, and others from fungi. [Fatty acid and phospholipid metabolism, Degradation]


Pssm-ID: 273828 [Multi-domain]  Cd Length: 212  Bit Score: 42.47  E-value: 3.61e-04
                          10        20        30        40        50        60        70
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 739666855  592 YRAAHTASNlEDHVAAIRQLAQH---NDQIDLDRVGITGFSGGGYMTAHAALRFGDFFK-VAVAGGGNYDQA 659
Cdd:TIGR01840  64 FFTHHRARG-TGEVESLHQLIDAvkaNYSIDPNRVYVTGLSAGGGMTAVLGCTYPDVFAgGASNAGLPYGEA 134
FrmB COG0627
S-formylglutathione hydrolase FrmB [Defense mechanisms];
621-736 1.76e-03

S-formylglutathione hydrolase FrmB [Defense mechanisms];


Pssm-ID: 440392 [Multi-domain]  Cd Length: 249  Bit Score: 40.97  E-value: 1.76e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 621 DRVGITGFSGGGYMTAHAALRFGDFFK--VAVAGGGNYDQALFWHSWGERYHGAYDAEHYAAQAAKTYAEGLTGKL-MLV 697
Cdd:COG0627  113 ERRAIAGLSMGGHGALTLALRHPDLFRavAAFSGILDPSQPPWGEKAFDAYFGPPDRAAWAANDPLALAEKLRAGLpLYI 192

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 739666855 698 H-GMLDHGCHPAGLfQLVQSLIDADKDVDLVLLPrGGHDW 736
Cdd:COG0627  193 DcGTADPFFLEANR-QLHAALRAAGIPHTYRERP-GGHSW 230
BD-FAE pfam20434
BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, ...
 529-640 2.76e-03

BD-FAE; This family represents a novel bifunctional feruloyl and acetyl xylan esterase (BD-FAE, previously known as bifunctional carbohydrate esterase (CE)), which is active on complex natural xylans and was identified as the basis of a monophyletic clade gathering all homologs identified in PULs (polysaccharide utilization loci) predicted to act on xylan. It adopts an alpha-beta-hydrolase fold with the catalytic triad Ser-Asp-His. This new family of proteins is a new candidate for biomass processing due to its capacity to remove ferulic acid and acetic acid from natural corn and birchwood xylan substrates.


Pssm-ID: 466583 [Multi-domain]  Cd Length: 215  Bit Score: 39.86  E-value: 2.76e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855  529 YPLIDLIYGGpqvhnvphsSFASGDigggTYVDAVHLASLGAYVLildgrgtanrEQDFRTAS--YRAAHTA---SNLED 603
Cdd:pfam20434  13 YPVVIWIHGG---------GWNSGD----KEADMGFMTNTVKALL----------KAGYAVASinYRLSTDAkfpAQIQD 69

                          90       100       110
                  ....*....|....*....|....*....|....*....
gi 739666855  604 HVAAIRQLAQHNDQ--IDLDRVGITGFSGGGYMTAHAAL 640
Cdd:pfam20434  70 VKAAIRFLRANAAKygIDTNKIALMGFSAGGHLALLAGL 108
COG4188 COG4188
Predicted dienelactone hydrolase [General function prediction only];
562-640 5.17e-03

Predicted dienelactone hydrolase [General function prediction only];


Pssm-ID: 443342 [Multi-domain]  Cd Length: 326  Bit Score: 39.71  E-value: 5.17e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 562 AVHLASLGAYVLILDGRGTANREQDFRTASYRAAHTASNLEDHVAAIR----QLAQHN-------DQIDLDRVGITGFSG 630
Cdd:COG4188   82 AEHLASHGYVVAAPDHPGSNAADLSAALDGLADALDPEELWERPLDLSfvldQLLALNksdpplaGRLDLDRIGVIGHSL 161

                         90
                 ....*....|
gi 739666855 631 GGYmTAHAAL 640
Cdd:COG4188  162 GGY-TALALA 170
TolB COG0823
Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, ...
 279-372 8.58e-03

Periplasmic component TolB of the Tol biopolymer transport system [Intracellular trafficking, secretion, and vesicular transport];


Pssm-ID: 440585 [Multi-domain]  Cd Length: 158  Bit Score: 37.73  E-value: 8.58e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666855 279 WSADSRTGYFVDIERGEQKVHVVafDVATGSTRTVfSEESASYVEVSVNvytkaliaplPATNELVWYSERSGRGHLYLY 358
Cdd:COG0823   38 WSPDGRRIAFTSDRGGGPQIYVV--DADGGEPRRL-TFGGGYNASPSWS----------PDGKRLAFVSRSDGRFDIYVL 104

                         90
                 ....*....|....
gi 739666855 359 DLATGSLRgAITQG 372
Cdd:COG0823  105 DLDGGAPR-RLTDG 117
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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