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Conserved domains on  [gi|739666854|ref|WP_037522129|]
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Tn3 family transposase [Sphingobium yanoikuyae]

Protein Classification

Tn3 family transposase( domain architecture ID 1750096)

Tn3 family transposase catalyzes DNA cleavage and strand transfer reactions necessary for formation of a cointegrate transposition intermediate during replicative transposition which is composed of donor (with the transposon) and target (without the transposon) circular DNA molecules fused into a single circular molecule and separated by two directly repeated transposon copies, one at each donor-target junction.

Gene Ontology:  GO:0003677|GO:0004803|GO:0006313
PubMed:  20615441

Graphical summary

 Zoom to residue level

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List of domain hits

Name Accession Description Interval E-value
transpos_Tn3 super family cl41305
Tn3 family transposase;
20-963 0e+00

Tn3 family transposase;


The actual alignment was detected with superfamily member NF033527:

Pssm-ID: 468061 [Multi-domain]  Cd Length: 954  Bit Score: 983.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  20 LDEREIARHYTLTSDDLEIVGRRRGDATRLGFAMLLLTMRWPGRALEAGEVPPAPVLAYVARQLGVAPEAFADYAHRDQT 99
Cdd:NF033527   1 LSEADLRRYFTLSDDDLALINSRRRDHNRLGFALQLGYLRYPGRFLGPGEEIPPGVLRFVAEQLGIGPDLLAEYATRGRT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 100 RREHLVEIRRSHGFRIFDRDAFREVAAFAIPIAQTIVHPGQMAGVIVDELRRRQILLPSSSILEAVLRRARQQAEQLTYE 179
Cdd:NF033527  81 RYEHRAEIRELLGYRLFDESDRRDLLRWLLEQAAWTDKPRQLADAAIEWLRRRKIIIPGYTTLERLIAEALSAAERRLAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 180 VLTNGLLPDTLQGLDDLLARRTGQAATWLSWLRNAPQSPAARNILRLIERLAHVRALGLDRGRADMIPASTFDRLADEGS 259
Cdd:NF033527 161 ALASALSPEQRQALDALLTSDRGDRLSRLAWLRQGPGRPSGREMLEELERLEPLRSLGLPLGILLGVPDKRLRHLAREGA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 260 RITPQHLGELNALRRHATLAATGIRLEESLTDATLTMFDKLLGSMVRRAENRTRDKALKTVRELQGHLRTLTGSCRILID 339
Cdd:NF033527 241 SYTPQDLRRLKPPRRYATLVAFLTEREATLTDDLIDMFDRLIGKLFRRAKRKAQKEVQASRKKLADKVRLLARLGKALLD 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 340 ARTNGVDSLAQIE-ALDWQRFAVAVEQAEVLGRPETVDRTAELIERHRTVKLFAGPFLNTFEFRGAGAVQGLLAALAIIA 418
Cdd:NF033527 321 AKEDGEDPFAAVRqVALWDRLAELVAEVCKLARPSREDFLAQMLESYGTLRRFLPPLLAALEFEAAPAAQPLLAALALLR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 419 ELYRTGKRRLPDRVPLRFVPSAWRPFVLR-DGIVDRAAYELCALSQLRERLRAGDIWVAGSRQFRNFDSYLIPPATYAAL 497
Cdd:NF033527 401 ELYASGRRKLPADAPTGFLRKRWRRLVLTpDGGIDRRAYELCVLFELRDRLRSGDVWVEGSRRYRDLEDYLIPPEEFQAD 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 498 REKGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKA-ATPPATEIARRAAYDRLPRVK 576
Cdd:NF033527 481 RLAYYLPLALPADAETFLQELLARLDARLAAVARRLPEGDLENRIITDKRLHITPLWAlDEPPSADRLRDQIYARLPPVD 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 577 ITDLLLEVDAWTGFSECFIHRRSG--READDRNALLTVILADGINLGLTRMAETCRGASLRQLAHLHDWHISEAAYGEAL 654
Cdd:NF033527 561 ITDLLLEVDAWTGFSRCFTHLSPRepRAKDELLSLLAALLADGTNLGLTRMARACPGVTYDQLSWVQAWYIRDETLRAAN 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 655 GRLIDAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVL 734
Cdd:NF033527 641 ARIVNAQAALPLAAHWGDGTTASSDGQKFETGRRTEKAGYVNKYFGSGPGVTAYTHVSDQYAPFHSQVIPANEREAAYVL 720
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 735 DGLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDE 814
Cdd:NF033527 721 DGLLRHESDLKIDEHYTDTHGYSDHVFALAHLLGFRFAPRIRDLGDRRLYLPDGDADYGELNPLLGGRIDLKLIEAHWDD 800
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 815 LLRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFN 894
Cdd:NF033527 801 ILRLAASLKLGTVTASLLLRKLGSYPRQNPLAQALRELGRIERTLFLLDYIDDEELRRRVQAGLNRGEARNALARAIFFG 880
                        890       900       910       920       930       940       950
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 739666854 895 QLGELRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADIA-----TPDEIARHIAPLGWEHISLTGDYSWN 963
Cdd:NF033527 881 RLGEIRDRRFEEQELRASALNLVANAIVLWNTLYLQRALTHLRargqtIPDELLRRLSPLGWEHINLTGDYLFT 954
 
Name Accession Description Interval E-value
transpos_Tn3 NF033527
Tn3 family transposase;
20-963 0e+00

Tn3 family transposase;


Pssm-ID: 468061 [Multi-domain]  Cd Length: 954  Bit Score: 983.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  20 LDEREIARHYTLTSDDLEIVGRRRGDATRLGFAMLLLTMRWPGRALEAGEVPPAPVLAYVARQLGVAPEAFADYAHRDQT 99
Cdd:NF033527   1 LSEADLRRYFTLSDDDLALINSRRRDHNRLGFALQLGYLRYPGRFLGPGEEIPPGVLRFVAEQLGIGPDLLAEYATRGRT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 100 RREHLVEIRRSHGFRIFDRDAFREVAAFAIPIAQTIVHPGQMAGVIVDELRRRQILLPSSSILEAVLRRARQQAEQLTYE 179
Cdd:NF033527  81 RYEHRAEIRELLGYRLFDESDRRDLLRWLLEQAAWTDKPRQLADAAIEWLRRRKIIIPGYTTLERLIAEALSAAERRLAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 180 VLTNGLLPDTLQGLDDLLARRTGQAATWLSWLRNAPQSPAARNILRLIERLAHVRALGLDRGRADMIPASTFDRLADEGS 259
Cdd:NF033527 161 ALASALSPEQRQALDALLTSDRGDRLSRLAWLRQGPGRPSGREMLEELERLEPLRSLGLPLGILLGVPDKRLRHLAREGA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 260 RITPQHLGELNALRRHATLAATGIRLEESLTDATLTMFDKLLGSMVRRAENRTRDKALKTVRELQGHLRTLTGSCRILID 339
Cdd:NF033527 241 SYTPQDLRRLKPPRRYATLVAFLTEREATLTDDLIDMFDRLIGKLFRRAKRKAQKEVQASRKKLADKVRLLARLGKALLD 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 340 ARTNGVDSLAQIE-ALDWQRFAVAVEQAEVLGRPETVDRTAELIERHRTVKLFAGPFLNTFEFRGAGAVQGLLAALAIIA 418
Cdd:NF033527 321 AKEDGEDPFAAVRqVALWDRLAELVAEVCKLARPSREDFLAQMLESYGTLRRFLPPLLAALEFEAAPAAQPLLAALALLR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 419 ELYRTGKRRLPDRVPLRFVPSAWRPFVLR-DGIVDRAAYELCALSQLRERLRAGDIWVAGSRQFRNFDSYLIPPATYAAL 497
Cdd:NF033527 401 ELYASGRRKLPADAPTGFLRKRWRRLVLTpDGGIDRRAYELCVLFELRDRLRSGDVWVEGSRRYRDLEDYLIPPEEFQAD 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 498 REKGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKA-ATPPATEIARRAAYDRLPRVK 576
Cdd:NF033527 481 RLAYYLPLALPADAETFLQELLARLDARLAAVARRLPEGDLENRIITDKRLHITPLWAlDEPPSADRLRDQIYARLPPVD 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 577 ITDLLLEVDAWTGFSECFIHRRSG--READDRNALLTVILADGINLGLTRMAETCRGASLRQLAHLHDWHISEAAYGEAL 654
Cdd:NF033527 561 ITDLLLEVDAWTGFSRCFTHLSPRepRAKDELLSLLAALLADGTNLGLTRMARACPGVTYDQLSWVQAWYIRDETLRAAN 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 655 GRLIDAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVL 734
Cdd:NF033527 641 ARIVNAQAALPLAAHWGDGTTASSDGQKFETGRRTEKAGYVNKYFGSGPGVTAYTHVSDQYAPFHSQVIPANEREAAYVL 720
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 735 DGLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDE 814
Cdd:NF033527 721 DGLLRHESDLKIDEHYTDTHGYSDHVFALAHLLGFRFAPRIRDLGDRRLYLPDGDADYGELNPLLGGRIDLKLIEAHWDD 800
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 815 LLRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFN 894
Cdd:NF033527 801 ILRLAASLKLGTVTASLLLRKLGSYPRQNPLAQALRELGRIERTLFLLDYIDDEELRRRVQAGLNRGEARNALARAIFFG 880
                        890       900       910       920       930       940       950
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 739666854 895 QLGELRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADIA-----TPDEIARHIAPLGWEHISLTGDYSWN 963
Cdd:NF033527 881 RLGEIRDRRFEEQELRASALNLVANAIVLWNTLYLQRALTHLRargqtIPDELLRRLSPLGWEHINLTGDYLFT 954
COG4644 COG4644
Transposase and inactivated derivatives, TnpA family [Mobilome: prophages, transposons];
500-985 0e+00

Transposase and inactivated derivatives, TnpA family [Mobilome: prophages, transposons];


Pssm-ID: 443682  Cd Length: 490  Bit Score: 545.77  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 500 KGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKAATPPATEIARRAAYDRLPRVKITD 579
Cdd:COG4644    1 AGLPALLLLPDAALTLLLRLLLLEARLLDVAAAAARGELLGGKIGKLLLKLPALDPPPPEAALRAALRRLLPLPPLIILL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 580 LLLEVDAWTGFSECFIHRRSGREADDRNALLTVILADGINLGLT-RMAETCRGASLRQLAHLHDWHISEAAYGEALGRLI 658
Cdd:COG4644   81 LLVDVDTGTGFFFFFTSLGRGRKPDDDRRLLLALLAAGGNNGLLpKMARASPGLSRDQLAWVARWYIREETLRAANAAIV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 659 DAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVLDGLL 738
Cdd:COG4644  161 NAQHRLPLAALWGDGTTASSDGQKFEVGVRNLLAGYSNRYYGREPGVTIYTHVSDQYAPFHSQVIPATEREAAYVLDGLL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 739 YHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDELLRF 818
Cdd:COG4644  241 RNETDLKPDEHYTDTHGYSDHVFALCHLLGFRFAPRIRDLKDRKLYRPDPPTRYEHLDPLIGGTINWDLIEEHWDDILRL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 819 ATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFNQLGE 898
Cdd:COG4644  321 AASIKLGTVSASTILRRLGSYSRQNPLYKALRELGRIERTLFLLDYLDDPELRRRIQAGLNKGEARNALARAIFFGRLGE 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 899 LRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADIAT-----PDEIARHIAPLGWEHISLTGDYSWNVEDRPDPdaL 973
Cdd:COG4644  401 IRDRTREEQEKRASALNLVANAIVLWNTLYLQRALEELRAegdeiPDELLAHLSPLGWEHINLTGDYDFDLERKLGG--L 478
                        490
                 ....*....|..
gi 739666854 974 RPLRAVSSLLAA 985
Cdd:COG4644  479 RPLRAPLALLLA 490
DDE_Tnp_Tn3 pfam01526
Tn3 transposase DDE domain; This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, ...
579-960 5.13e-177

Tn3 transposase DDE domain; This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.


Pssm-ID: 426307  Cd Length: 389  Bit Score: 519.76  E-value: 5.13e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  579 DLLLEVDAWTGFSECFIHRRSG--READDRNALLTVILADGINLGLTRMAETCRGASLRQLAHLHDWHISEAAYGEALGR 656
Cdd:pfam01526   1 DLLLEVDAWTGFTRAFTHLSGRepRSKDELRRLLAALLAYGTNLGLKRMARAIPGLSYDQLAWVNRRYIREETLRAANAA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  657 LIDAHRTMPLAALWGDGTTSSSDGQQFHAGgRGAAIGDINAR-SGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVLD 735
Cdd:pfam01526  81 IVNAQARLPLARLWGDGTTASSDGQKFEAP-VQNLLARYNPRyFGRGRGVTIYTHVSDQYIPLHSQVIPCTEREAHYVLD 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  736 GLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDEL 815
Cdd:pfam01526 160 GLLRNTSDLQPDEHYTDTHGYSDVVFALAHLLGFQFAPRLRDLKDRKLYRPDAGADYPHLDPLLGRRINWDLIEEHWDDI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  816 LRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFNQ 895
Cdd:pfam01526 240 LRVAASIKLGTVSASTILRKLGSYSRQNPLYKALRELGRIIRTLFLLDYLDDPDLRREIQAGLNKGEARHALARAIFFGK 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  896 LGELRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADI-----ATPDEIARHIAPLGWEHISLTGDY 960
Cdd:pfam01526 320 GGEIRDRRREEQEKRASALNLVANAIVLWNTVYLQRALEQLraegeDVTDEDLARLSPLGWEHINLFGRY 389
 
Name Accession Description Interval E-value
transpos_Tn3 NF033527
Tn3 family transposase;
20-963 0e+00

Tn3 family transposase;


Pssm-ID: 468061 [Multi-domain]  Cd Length: 954  Bit Score: 983.29  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  20 LDEREIARHYTLTSDDLEIVGRRRGDATRLGFAMLLLTMRWPGRALEAGEVPPAPVLAYVARQLGVAPEAFADYAHRDQT 99
Cdd:NF033527   1 LSEADLRRYFTLSDDDLALINSRRRDHNRLGFALQLGYLRYPGRFLGPGEEIPPGVLRFVAEQLGIGPDLLAEYATRGRT 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 100 RREHLVEIRRSHGFRIFDRDAFREVAAFAIPIAQTIVHPGQMAGVIVDELRRRQILLPSSSILEAVLRRARQQAEQLTYE 179
Cdd:NF033527  81 RYEHRAEIRELLGYRLFDESDRRDLLRWLLEQAAWTDKPRQLADAAIEWLRRRKIIIPGYTTLERLIAEALSAAERRLAA 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 180 VLTNGLLPDTLQGLDDLLARRTGQAATWLSWLRNAPQSPAARNILRLIERLAHVRALGLDRGRADMIPASTFDRLADEGS 259
Cdd:NF033527 161 ALASALSPEQRQALDALLTSDRGDRLSRLAWLRQGPGRPSGREMLEELERLEPLRSLGLPLGILLGVPDKRLRHLAREGA 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 260 RITPQHLGELNALRRHATLAATGIRLEESLTDATLTMFDKLLGSMVRRAENRTRDKALKTVRELQGHLRTLTGSCRILID 339
Cdd:NF033527 241 SYTPQDLRRLKPPRRYATLVAFLTEREATLTDDLIDMFDRLIGKLFRRAKRKAQKEVQASRKKLADKVRLLARLGKALLD 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 340 ARTNGVDSLAQIE-ALDWQRFAVAVEQAEVLGRPETVDRTAELIERHRTVKLFAGPFLNTFEFRGAGAVQGLLAALAIIA 418
Cdd:NF033527 321 AKEDGEDPFAAVRqVALWDRLAELVAEVCKLARPSREDFLAQMLESYGTLRRFLPPLLAALEFEAAPAAQPLLAALALLR 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 419 ELYRTGKRRLPDRVPLRFVPSAWRPFVLR-DGIVDRAAYELCALSQLRERLRAGDIWVAGSRQFRNFDSYLIPPATYAAL 497
Cdd:NF033527 401 ELYASGRRKLPADAPTGFLRKRWRRLVLTpDGGIDRRAYELCVLFELRDRLRSGDVWVEGSRRYRDLEDYLIPPEEFQAD 480
                        490       500       510       520       530       540       550       560
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 498 REKGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKA-ATPPATEIARRAAYDRLPRVK 576
Cdd:NF033527 481 RLAYYLPLALPADAETFLQELLARLDARLAAVARRLPEGDLENRIITDKRLHITPLWAlDEPPSADRLRDQIYARLPPVD 560
                        570       580       590       600       610       620       630       640
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 577 ITDLLLEVDAWTGFSECFIHRRSG--READDRNALLTVILADGINLGLTRMAETCRGASLRQLAHLHDWHISEAAYGEAL 654
Cdd:NF033527 561 ITDLLLEVDAWTGFSRCFTHLSPRepRAKDELLSLLAALLADGTNLGLTRMARACPGVTYDQLSWVQAWYIRDETLRAAN 640
                        650       660       670       680       690       700       710       720
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 655 GRLIDAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVL 734
Cdd:NF033527 641 ARIVNAQAALPLAAHWGDGTTASSDGQKFETGRRTEKAGYVNKYFGSGPGVTAYTHVSDQYAPFHSQVIPANEREAAYVL 720
                        730       740       750       760       770       780       790       800
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 735 DGLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDE 814
Cdd:NF033527 721 DGLLRHESDLKIDEHYTDTHGYSDHVFALAHLLGFRFAPRIRDLGDRRLYLPDGDADYGELNPLLGGRIDLKLIEAHWDD 800
                        810       820       830       840       850       860       870       880
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 815 LLRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFN 894
Cdd:NF033527 801 ILRLAASLKLGTVTASLLLRKLGSYPRQNPLAQALRELGRIERTLFLLDYIDDEELRRRVQAGLNRGEARNALARAIFFG 880
                        890       900       910       920       930       940       950
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 739666854 895 QLGELRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADIA-----TPDEIARHIAPLGWEHISLTGDYSWN 963
Cdd:NF033527 881 RLGEIRDRRFEEQELRASALNLVANAIVLWNTLYLQRALTHLRargqtIPDELLRRLSPLGWEHINLTGDYLFT 954
COG4644 COG4644
Transposase and inactivated derivatives, TnpA family [Mobilome: prophages, transposons];
500-985 0e+00

Transposase and inactivated derivatives, TnpA family [Mobilome: prophages, transposons];


Pssm-ID: 443682  Cd Length: 490  Bit Score: 545.77  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 500 KGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKAATPPATEIARRAAYDRLPRVKITD 579
Cdd:COG4644    1 AGLPALLLLPDAALTLLLRLLLLEARLLDVAAAAARGELLGGKIGKLLLKLPALDPPPPEAALRAALRRLLPLPPLIILL 80
                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 580 LLLEVDAWTGFSECFIHRRSGREADDRNALLTVILADGINLGLT-RMAETCRGASLRQLAHLHDWHISEAAYGEALGRLI 658
Cdd:COG4644   81 LLVDVDTGTGFFFFFTSLGRGRKPDDDRRLLLALLAAGGNNGLLpKMARASPGLSRDQLAWVARWYIREETLRAANAAIV 160
                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 659 DAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVLDGLL 738
Cdd:COG4644  161 NAQHRLPLAALWGDGTTASSDGQKFEVGVRNLLAGYSNRYYGREPGVTIYTHVSDQYAPFHSQVIPATEREAAYVLDGLL 240
                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 739 YHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDELLRF 818
Cdd:COG4644  241 RNETDLKPDEHYTDTHGYSDHVFALCHLLGFRFAPRIRDLKDRKLYRPDPPTRYEHLDPLIGGTINWDLIEEHWDDILRL 320
                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 819 ATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFNQLGE 898
Cdd:COG4644  321 AASIKLGTVSASTILRRLGSYSRQNPLYKALRELGRIERTLFLLDYLDDPELRRRIQAGLNKGEARNALARAIFFGRLGE 400
                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854 899 LRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADIAT-----PDEIARHIAPLGWEHISLTGDYSWNVEDRPDPdaL 973
Cdd:COG4644  401 IRDRTREEQEKRASALNLVANAIVLWNTLYLQRALEELRAegdeiPDELLAHLSPLGWEHINLTGDYDFDLERKLGG--L 478
                        490
                 ....*....|..
gi 739666854 974 RPLRAVSSLLAA 985
Cdd:COG4644  479 RPLRAPLALLLA 490
DDE_Tnp_Tn3 pfam01526
Tn3 transposase DDE domain; This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, ...
579-960 5.13e-177

Tn3 transposase DDE domain; This family includes transposases of Tn3, Tn21, Tn1721, Tn2501, Tn3926 transposons from E-coli. The specific binding of the Tn3 transposase to DNA has been demonstrated. Sequence analysis has suggested that the invariant triad of Asp689, Asp765, Glu895 (numbering as in Tn3) may correspond to the D-D-35-E motif previously implicated in the catalysis of numerous transposases.


Pssm-ID: 426307  Cd Length: 389  Bit Score: 519.76  E-value: 5.13e-177
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  579 DLLLEVDAWTGFSECFIHRRSG--READDRNALLTVILADGINLGLTRMAETCRGASLRQLAHLHDWHISEAAYGEALGR 656
Cdd:pfam01526   1 DLLLEVDAWTGFTRAFTHLSGRepRSKDELRRLLAALLAYGTNLGLKRMARAIPGLSYDQLAWVNRRYIREETLRAANAA 80
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  657 LIDAHRTMPLAALWGDGTTSSSDGQQFHAGgRGAAIGDINAR-SGNEPGVAFYTHVSDRYDPFASRVIAATAGEAPYVLD 735
Cdd:pfam01526  81 IVNAQARLPLARLWGDGTTASSDGQKFEAP-VQNLLARYNPRyFGRGRGVTIYTHVSDQYIPLHSQVIPCTEREAHYVLD 159
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  736 GLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGYRFAPRLRDIKERRLHLLPGQESGPLLGGMTAEPIALGHVAAHWDEL 815
Cdd:pfam01526 160 GLLRNTSDLQPDEHYTDTHGYSDVVFALAHLLGFQFAPRLRDLKDRKLYRPDAGADYPHLDPLLGRRINWDLIEEHWDDI 239
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  816 LRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAGLNKGEARNALARALFFNQ 895
Cdd:pfam01526 240 LRVAASIKLGTVSASTILRKLGSYSRQNPLYKALRELGRIIRTLFLLDYLDDPDLRREIQAGLNKGEARHALARAIFFGK 319
                         330       340       350       360       370       380       390
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  896 LGELRDRRFENQTYRASGLNLLVAAIILWNTRYLEMALADI-----ATPDEIARHIAPLGWEHISLTGDY 960
Cdd:pfam01526 320 GGEIRDRRREEQEKRASALNLVANAIVLWNTVYLQRALEQLraegeDVTDEDLARLSPLGWEHINLFGRY 389
DUF4158 pfam13700
Domain of unknown function (DUF4158); The exact function of this domain is not clear, but it ...
20-169 5.90e-49

Domain of unknown function (DUF4158); The exact function of this domain is not clear, but it frequently occurs as an N-terminal region of transposase 3 or IS3 family of insertion elements.


Pssm-ID: 433413  Cd Length: 165  Bit Score: 170.82  E-value: 5.90e-49
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854   20 LDEREIARHYTLTSDDLEIVGRRRGDATRLGFAMLLLTMRWPGRALEAGEVPPAPVLAYVARQLGVAPEAFADYAHRDQT 99
Cdd:pfam13700  16 DSEEELARYFTLSDEDLALINQRRGPHNRLGFAVQLCYFRYPGRFLSDPEDVPAAVVEYIAEQLGLDPSALARYARREQT 95
                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  100 RREHLVEIRRSHGFRIFDRDAFREVAAFAIPIAQTIVHPGQMAGVIVDELRRRQILLPSSSILEAVLRRA 169
Cdd:pfam13700  96 RREHLAEIRELLGYRPFTDSDYRELIRWLAQLATVTDRPIDLFDEAIEELRRRRILLPGYTTLERLVAEA 165
PksD COG3321
Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites ...
328-905 2.39e-03

Acyl transferase domain in polyketide synthase (PKS) enzymes [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442550 [Multi-domain]  Cd Length: 1386  Bit Score: 42.17  E-value: 2.39e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  328 RTLTGSCR-ILIDARTNGVDSLAQIEALDWQRFAVAVEQAEVLGRPetVDRTA-ELIERHRTVKL--------FAGPFLN 397
Cdd:COG3321   801 PVLTGLVRqCLAAAGDAVVLPSLRRGEDELAQLLTALAQLWVAGVP--VDWSAlYPGRGRRRVPLptypfqreDAAAALL 878
                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  398 TFEFRGAGAVQGLLAALAIIAELYRTGKRRLPDRVPLRFVPSAWRPFVLRDGIVDRAAYELCALSQLRERLRAGDIWVAG 477
Cdd:COG3321   879 AAALAAALAAAAALGALLLAALAAALAAALLALAAAAAAALALAAAALAALLALVALAAAAAALLALAAAAAAAAAALAA 958
                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  478 SRQFRNFDSYLIPPATYAALREKGPLPLAIETDFERHIEERRTRLDTAIEQVTVLARQGELPQVRLDENGLIISPLKAAT 557
Cdd:COG3321   959 AEAGALLLLAAAAAAAAAAAAAAAAAAAAAAAAAAAALAAAAALALLAAAALLLAAAAAAAALLALAALLAAAAAALAAA 1038
                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  558 PPATEIARRAAYDRLPRVKITDLLLEVDAWTGFSECFIHRRSGREADDRNALLTVILADGINLGLTRMAETCRGASLRQL 637
Cdd:COG3321  1039 AAAAAAAAALAALAAAAAAAAALALALAALLLLAALAELALAAAALALAAALAAAALALALAALAAALLLLALLAALALA 1118
                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  638 AHLHDWHISEAAYGEALGRLIDAHRTMPLAALWGDGTTSSSDGQQFHAGGRGAAIGDINARSGNEPGVAFYTHVSDRYDP 717
Cdd:COG3321  1119 AAAAALLALAALLAAAAAAAALAAAAAAAAALALAAAAAALAAALAAALLAAAALLLALALALAAALAAALAGLAALLLA 1198
                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  718 FASRVIAATAGEAPYVLDGLLYHQTGLTIEEHYTDTGGASDHVFGLMPFFGyRFAPRLRDIKERRLHLLPGQESGPLLGG 797
Cdd:COG3321  1199 ALLAALLAALLALALAALAAAAAALLAAAAAAAALALLALAAAAAAVAALA-AAAAALLAALAALALLAAAAGLAALAAA 1277
                         490       500       510       520       530       540       550       560
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 739666854  798 MTAEPIALGHVAAHWDELLRFATSIRTGTVTASAMLRRLSAYPRQNGLALALRELGRLERSIFMLDWLRDIDLRRRTQAG 877
Cdd:COG3321  1278 AAAAAAALALAAAAAAAAAALAALLAAAAAAAAAAAAAAAAAALAAALLAAALAALAAAVAAALALAAAAAAAAAAAAAA 1357
                         570       580
                  ....*....|....*....|....*...
gi 739666854  878 LNKGEARNALARALFFNQLGELRDRRFE 905
Cdd:COG3321  1358 AAAAALAAAAGAAAAAAALALAALAAAV 1385
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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