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Conserved domains on  [gi|738993273|ref|WP_036875488|]
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isoprenyl transferase [Prevotella bivia]

Protein Classification

undecaprenyl diphosphate synthase family protein( domain architecture ID 10000255)

undecaprenyl diphosphate synthase (UPPS) family protein catalyzes consecutive condensation reactions of farnesyl diphosphate (FPP) with specific numbers of isopentenyl diphosphate (IPP) to form long-chain polyprenyl diphosphates, similar to UPPS that catalyzes chain elongation of FPP by eight IPP to form the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis

Gene Ontology:  GO:0016765|GO:0000287|GO:0002094
PubMed:  22471620

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
1-247 6.39e-154

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


:

Pssm-ID: 439791  Cd Length: 248  Bit Score: 427.94  E-value: 6.39e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMG 80
Cdd:COG0020    6 LLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  81 LVLSSLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNI 158
Cdd:COG0020   86 LLREYLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGEL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 159 QLTAdnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQR 238
Cdd:COG0020  166 DPED------IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRER 239


                 ....*....
gi 738993273 239 RFGKTGNQI 247
Cdd:COG0020  240 RFGGTSEQV 248
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
1-247 6.39e-154

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 427.94  E-value: 6.39e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMG 80
Cdd:COG0020    6 LLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  81 LVLSSLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNI 158
Cdd:COG0020   86 LLREYLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGEL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 159 QLTAdnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQR 238
Cdd:COG0020  166 DPED------IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRER 239


                 ....*....
gi 738993273 239 RFGKTGNQI 247
Cdd:COG0020  240 RFGGTSEQV 248
PRK14838 PRK14838
isoprenyl transferase;
1-248 1.11e-136

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 384.23  E-value: 1.11e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMG 80
Cdd:PRK14838   1 YKEQIDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  81 LVLSSLEDEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQL 160
Cdd:PRK14838  81 LLLDSIEEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 161 tadnikEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRF 240
Cdd:PRK14838 161 ------EEITEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRF 234


                 ....*...
gi 738993273 241 GKTGNQIE 248
Cdd:PRK14838 235 GKTSEQIS 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 17-241 2.29e-135

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 379.79  E-value: 2.29e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   17 IMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGL-VLSSLEDEI--FMK 93
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELlKEEYLRRELpeLHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   94 NDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIqltadnikEYITEDT 173
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKKLDP--------EDIDEEL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273  174 ISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:pfam01255 153 ISSHLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 13-235 4.84e-134

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 376.71  E-value: 4.84e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  13 HIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI-- 90
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELee 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  91 FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLtadnikEYIT 170
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDP------EDIT 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738993273 171 EDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQR 235
Cdd:cd00475  155 EELISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 12-241 1.78e-105

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 304.71  E-value: 1.78e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   12 EHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI- 90
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   91 -FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLtadnikEYI 169
Cdd:TIGR00055  81 eLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLP------EDI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738993273  170 TEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:TIGR00055 155 DEETLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
 
Name Accession Description Interval E-value
UppS COG0020
Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];
1-247 6.39e-154

Undecaprenyl pyrophosphate synthase [Lipid transport and metabolism];


Pssm-ID: 439791  Cd Length: 248  Bit Score: 427.94  E-value: 6.39e-154
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMG 80
Cdd:COG0020    6 LLPEIDPGNLPRHVAIIMDGNGRWAKKRGLPRIEGHRAGVEAVREVVEACAELGIKYLTLYAFSTENWKRPKEEVSFLMG 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  81 LVLSSLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNI 158
Cdd:COG0020   86 LLREYLRRELdeLHKNNVRVRVIGDRSRLPESLQEAIEEAEELTKNNTGLTLNIALNYGGRWEIVDAVRKIARDVAAGEL 165

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 159 QLTAdnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQR 238
Cdd:COG0020  166 DPED------IDEETISRYLYTADLPDPDLLIRTSGEQRISNFLLWQLAYAELYFTDVLWPDFDKEDLLRAIRDYQRRER 239


                 ....*....
gi 738993273 239 RFGKTGNQI 247
Cdd:COG0020  240 RFGGTSEQV 248
PRK14838 PRK14838
isoprenyl transferase;
1-248 1.11e-136

isoprenyl transferase;


Pssm-ID: 184846  Cd Length: 242  Bit Score: 384.23  E-value: 1.11e-136
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMG 80
Cdd:PRK14838   1 YKEQIDMNRIPQHIAIIMDGNGRWAKERGKERSFGHQAGAETVHIITEEAARLGVKFLTLYTFSTENWNRPSDEVAALMS 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  81 LVLSSLEDEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQL 160
Cdd:PRK14838  81 LLLDSIEEETFMKNNIRFRIIGDIAKLPEEVQERLNECEEHTAKNTGMCLVLALSYSSRWEITEATRQIATLVQNGELNP 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 161 tadnikEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRF 240
Cdd:PRK14838 161 ------EEITEESISEHLTTNFMPDPDLLIRTGGEIRLSNYLLWQCAYSELYFCDTFWPDFDEEELCKAIYDYQKRERRF 234


                 ....*...
gi 738993273 241 GKTGNQIE 248
Cdd:PRK14838 235 GKTSEQIS 242
Prenyltransf pfam01255
Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family ...
 17-241 2.29e-135

Putative undecaprenyl diphosphate synthase; Previously known as uncharacterized protein family UPF0015, a single member of this family has been identified as an undecaprenyl diphosphate synthase.


Pssm-ID: 460138  Cd Length: 220  Bit Score: 379.79  E-value: 2.29e-135
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   17 IMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGL-VLSSLEDEI--FMK 93
Cdd:pfam01255   1 IMDGNRRWAKKRGLPREAGHRAGAEALREVLEWCLELGIKYLTLYAFSTENWKRPKEEVDALMELlKEEYLRRELpeLHK 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   94 NDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIqltadnikEYITEDT 173
Cdd:pfam01255  81 NGVRVRVIGDLSLLPEDLQEAIEEAEEATKNNTGLTLNIALNYGGRDEIVDAVRKIVKEGKKLDP--------EDIDEEL 152

                         170       180       190       200       210       220
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273  174 ISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:pfam01255 153 ISSHLYTAGLPDPDLLIRTSGEQRLSNFLLWQSAYSELYFTDVLWPDFRKEDLLRAIRDYQRRERRFG 220
Cis_IPPS cd00475
Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) ...
 13-235 4.84e-134

Cis (Z)-Isoprenyl Diphosphate Synthases; Cis (Z)-Isoprenyl Diphosphate Synthases (cis-IPPS) catalyze the successive 1'-4 condensation of the isopentenyl diphosphate (IPP) molecule to trans,trans-farnesyl diphosphate (FPP) or to cis,trans-FPP to form long-chain polyprenyl diphosphates. A few can also catalyze the condensation of IPP to trans-geranyl diphosphate to form the short-chain cis,trans- FPP. In prokaryotes, the cis-IPPS, undecaprenyl diphosphate synthase (UPP synthase), catalyzes the formation of the carrier lipid UPP in bacterial cell wall peptidoglycan biosynthesis. Similarly, in eukaryotes, the cis-IPPS, dehydrodolichyl diphosphate (dedol-PP) synthase catalyzes the formation of the polyisoprenoid glycosyl carrier lipid dolichyl monophosphate. cis-IPPS form homodimers and are mechanistically and structurally distinct from trans-IPPS, which lack the DDXXD motifs, yet require Mg2+ for activity.


Pssm-ID: 259850  Cd Length: 219  Bit Score: 376.71  E-value: 4.84e-134
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  13 HIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI-- 90
Cdd:cd00475    1 HVAIIMDGNRRWAKKRGLPRTEGHRAGAEALREILEWCLELGIKYLTLYAFSTENWKRPKEEVDALMKLLREYLEKELee 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  91 FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLtadnikEYIT 170
Cdd:cd00475   81 LHKNGVRLRVIGDLSLLPEDLREAIEEAEEATKNNTGLTLNIALNYGGRDEIVRAVRKIARDVKAGELDP------EDIT 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738993273 171 EDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQR 235
Cdd:cd00475  155 EELISKHLYTADLPDPDLLIRTSGEQRLSNFLLWQSAYAELYFTDVLWPDFRKEDLLRAILDYQR 219
PRK14830 PRK14830
undecaprenyl pyrophosphate synthase; Provisional
 5-243 9.35e-129

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184840  Cd Length: 251  Bit Score: 364.58  E-value: 9.35e-129
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   5 LDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLS 84
Cdd:PRK14830  17 LDKGNIPKHIAIIMDGNGRWAKKRMLPRIAGHKAGMDTVKKITKAASELGVKVLTLYAFSTENWKRPKDEVKFLMNLPVE 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  85 SLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLta 162
Cdd:PRK14830  97 FLDKFVpeLIENNVKVNVIGDTDRLPEHTLRALEKAIEKTKNNTGLILNFALNYGGRAEIVSAVKEIAKDVLDGKLNP-- 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 163 dnikEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14830 175 ----EDITEELISNYLMTKGLPDPDLLIRTSGELRLSNFLLWQLAYSEFYFTDVLWPDFDEEELLKAIKDYQSRQRRFGG 250


                 .
gi 738993273 243 T 243
Cdd:PRK14830 251 V 251
PRK14836 PRK14836
undecaprenyl pyrophosphate synthase; Provisional
 10-252 9.05e-116

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237831  Cd Length: 253  Bit Score: 331.65  E-value: 9.05e-116
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  10 IPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDE 89
Cdd:PRK14836  14 IPRHIAIIMDGNGRWAKRRGKPRVEGHRAGVRAVRRTIEFCLEKGIEMLTLFAFSSENWLRPADEVSALMELFLKALDRE 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  90 I--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLtadnikE 167
Cdd:PRK14836  94 VdkLHRNGIRVRFIGDRSRLSPKLQERMEYAERLTASNTRLILSLAVSYGGRWDIVTAARALAREVAAGKLAP------D 167

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 168 YITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGKTGNQI 247
Cdd:PRK14836 168 EIDEALLAQHLALADLPEPDLFIRTSGELRISNFLLWQLAYTELYFTDTLWPDFDAQELQQALEDYASRERRFGKTSAQI 247


                 ....*
gi 738993273 248 ENENK 252
Cdd:PRK14836 248 ADRAT 252
uppS TIGR00055
undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule ...
 12-241 1.78e-105

undecaprenyl diphosphate synthase; This enzyme builds undecaprenyl diphosphate, a molecule that in bacteria is used a carrier in synthesizing cell wall components. Alternate name: undecaprenyl pyrophosphate synthetase. Activity has been demonstrated experimentally for members of this family from Micrococcus luteus, E. coli, Haemophilus influenzae, and Streptococcus pneumoniae. [Cell envelope, Biosynthesis and degradation of surface polysaccharides and lipopolysaccharides]


Pssm-ID: 129165  Cd Length: 226  Bit Score: 304.71  E-value: 1.78e-105
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   12 EHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI- 90
Cdd:TIGR00055   1 RHVAIIMDGNGRWAKKKGKPRAYGHKAGVKSLRRILRWCANLGVECLTLYAFSTENWKRPKEEVDFLMELFEKKLDREVk 80

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   91 -FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLtadnikEYI 169
Cdd:TIGR00055  81 eLHRYNVRIRIIGDLSLLSKELQEKIKKAEEDTKNNTDFTLNIAFNYGGRNEILHAVKQIAEKVKSGKLLP------EDI 154

                         170       180       190       200       210       220       230
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 738993273  170 TEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:TIGR00055 155 DEETLNKHLYTANLPPVDLLIRTSGEMRISNFLLWQSSYAELYFTDILWPDFDPQDFELAILDFQFRHRRFG 226
PRK14831 PRK14831
undecaprenyl pyrophosphate synthase; Provisional
 5-242 1.70e-100

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 184841  Cd Length: 249  Bit Score: 292.62  E-value: 1.70e-100
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   5 LDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLS 84
Cdd:PRK14831  15 LDPQRLPKHVAVIMDGNGRWAKRRGLPRIMGHRRGVDALKDLLRCCKDWGIGALTAYAFSTENWSRPLEEVNFLMTLFER 94

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  85 SLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLTA 162
Cdd:PRK14831  95 VLRRELeeLMEENVRIRFVGDLDPLPKSLQEEISRSTELTKNNNGIHFNVCTNYGGRQEIVQAARAIAQQVQQGELDPSE 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 163 dnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14831 175 ------IDENLFESELYTAGIKDPDLLIRTSGEMRISNFLLWQLAYAEIYVTDVLWPDFDRDEFHKALLDYQSRERRFGG 248
PRK14834 PRK14834
isoprenyl transferase;
6-244 7.51e-99

isoprenyl transferase;


Pssm-ID: 237829  Cd Length: 249  Bit Score: 288.58  E-value: 7.51e-99
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   6 DMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVlss 85
Cdd:PRK14834  10 DAMSVPRHVAIIMDGNGRWAKARGLPRAAGHRAGVEALRRVVRAAGELGIGYLTLFAFSSENWSRPASEVSDLFGLL--- 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  86 ledEIFMKND--------ARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQn 157
Cdd:PRK14834  87 ---RLFIRRDlaelhrngVRVRVIGERAGLEADICALLNEAEELTRNNTGLNLVIAFNYGSRDEIARAVRRLAREVAEG- 162

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 158 iQLTADNikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQ 237
Cdd:PRK14834 163 -RLDPAS----IDAETISANLDTADIPDPDLIIRTSGEQRLSNFLLWQAAYSELLFVPIHWPDFDKAALEAAIEEYARRE 237

                        250
                 ....*....|.
gi 738993273 238 RRFG----KTG 244
Cdd:PRK14834 238 RRFGglaaKTG 248
PRK14833 PRK14833
di-trans,poly-cis-decaprenylcistransferase;
7-241 1.80e-91

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237828  Cd Length: 233  Bit Score: 269.38  E-value: 1.80e-91
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   7 MTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSL 86
Cdd:PRK14833   1 MDNTLKHLAIIMDGNGRWAKLRGKARAAGHKKGVKTLREITIWCANHKLECLTLYAFSTENWKRPKSEVDFLMKLLKKYL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  87 EDE--IFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIalelqqqnIQLTADN 164
Cdd:PRK14833  81 KDErsTYLENNIRFKAIGDLEGFSKELRDTILQLEEDTRSFKGFTQVLALNYGSKDEISRAFKKL--------LESPPSH 152

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273 165 IKEY-ITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:PRK14833 153 IGELeSLEEEISNCLDTADLPEVDLLIRTGGEMRLSNFLLWQSSYAELFFTPILWPDFTPKDLENIISDFYKRVRKFG 230
PRK14832 PRK14832
undecaprenyl pyrophosphate synthase; Provisional
 5-242 9.90e-88

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237827  Cd Length: 253  Bit Score: 260.70  E-value: 9.90e-88
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   5 LDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLS 84
Cdd:PRK14832  13 LDPQKIPQHIAVIMDGNGRWATSQGLPRIAGHRQGARTLKELLRCCKDWGIKALTAYAFSTENWQRPIEEVDFLMLLFER 92

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  85 SLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLTA 162
Cdd:PRK14832  93 LLRRELaqMHREGVRISFIGDLSALPKSLQTEMERSMTETLNNQAIHFTVAVNYGSRNEITRACRQVAELVQQGKLSADA 172

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 163 dnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14832 173 ------VNEQLVEQHLYTADTPPPDLLIRTSGEMRLSNFLLWQMAYTEMYFTDILWPDFDRAAFHQALLSYQKRDRRFGQ 246
PRK14839 PRK14839
di-trans,poly-cis-decaprenylcistransferase;
13-241 2.28e-77

di-trans,poly-cis-decaprenylcistransferase;


Pssm-ID: 237832  Cd Length: 239  Bit Score: 233.88  E-value: 2.28e-77
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  13 HIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI-- 90
Cdd:PRK14839  12 HVAIIMDGNGRWATARGLPRLAGHRAGVEAIRRVVEAAPDLGIGTLTLYAFSSDNWRRPAAEVGGLMRLLRAYLRNETer 91

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  91 FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDiALELQQqniqltadnikeyIT 170
Cdd:PRK14839  92 LARNGVRLTVIGRRDRLPDGIPEAIARAEAATAGGDRLHLRIAVDYSARDAILAAAAK-ALGPEG-------------LS 157

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 738993273 171 EDTISKhLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:PRK14839 158 REAFSD-LLTGDGGDVDLLIRTGGEKRLSDFLLWESAYAELHFTDRMWPDFGADDLAAAVADFHGRERRFG 227
PRK10240 PRK10240
(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;
18-243 6.30e-75

(2E,6E)-farnesyl-diphosphate-specific ditrans,polycis-undecaprenyl-diphosphate synthase;


Pssm-ID: 182326  Cd Length: 229  Bit Score: 227.17  E-value: 6.30e-75
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  18 MDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLEDEI--FMKND 95
Cdd:PRK10240   1 MDGNGRWAKKQGKIRAFGHKAGAKSVRRAVSFAANNGIEALTLYAFSSENWNRPAQEVSALMELFVWALDSEVksLHRHN 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  96 ARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQltadniKEYITEDTIS 175
Cdd:PRK10240  81 VRLRIIGDTSRFNSRLQERIRKSEALTAGNTGLTLNIAANYGGRWDIVQGVRQLAEQVQQGNLQ------PDQIDEEMLN 154

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273 176 KHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGKT 243
Cdd:PRK10240 155 QHICMHELAPVDLVIRTGGEHRISNFLLWQIAYAELYFTDVLWPDFDEQDFEGALNAFANRERRFGGT 222
PRK14840 PRK14840
undecaprenyl pyrophosphate synthase; Provisional
 2-242 5.54e-74

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173301  Cd Length: 250  Bit Score: 225.49  E-value: 5.54e-74
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   2 EKTLDMTRIPEHIAIIMDGNGRWAQK----RNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVST 77
Cdd:PRK14840  10 ENFPSLQSLPRHVAIIMDGNRRWYRKheqfCQKRAISGHYYGAKSLPQIVDTALHLGIEVLTLFAFSTENFSRSKEEVAE 89

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  78 LMGLVLSSLEDEI--FMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQ 155
Cdd:PRK14840  90 LFSLFNSQLDSQLpyLHENEIRLRCIGDLSKLPQELQNNIEQASSATAHYSRMELVLAINYGGKDELVRAFKKLHQDLAN 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 156 QNIQLTAdnikeyITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQR 235
Cdd:PRK14840 170 KKISSDD------ISEELISSYLDTSGLPDPDLLIRTGGEMRVSNFLLWQIAYTELYVTDVLWPDFTPNDLLEAIKTYQQ 243


                 ....*..
gi 738993273 236 RQRRFGK 242
Cdd:PRK14840 244 RSRRGGK 250
PRK14829 PRK14829
undecaprenyl pyrophosphate synthase; Provisional
 10-243 3.82e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237826  Cd Length: 243  Bit Score: 223.12  E-value: 3.82e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  10 IPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSL--E 87
Cdd:PRK14829  14 LPRHIAVVMDGNGRWATQRGLKRTEGHKAGEPVLFDVVAGAIEAGVPYLSLYTFSTENWKRSPDEVRFLMGFSRDVIhrR 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  88 DEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQltadniKE 167
Cdd:PRK14829  94 REQMDEWGVRVRWSGRRPRLWKSVIDELEAAEELTKNNTTMDLVFCVNYGGRAEIADAAAAIAREVRDGKIS------GD 167

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 738993273 168 YITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGKT 243
Cdd:PRK14829 168 RVTEKMISDHLYNPDMPDVDLFLRTSGEQRTSNFLLWQSAYAELDFVPKLFPDFGRDDLWAAIDEYAHRDRRFGGV 243
PRK14841 PRK14841
undecaprenyl pyrophosphate synthase; Provisional
 9-245 9.50e-73

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173302  Cd Length: 233  Bit Score: 221.79  E-value: 9.50e-73
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   9 RIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSL-- 86
Cdd:PRK14841   2 RIPQHVAIIMDGNGRWAKKRGLPRIKGHQRGAEVLHNTVKWSLELGIKYLTAFSFSTENWKRPKEEVEFLMDLFVQMIdr 81

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  87 EDEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNiqltadniK 166
Cdd:PRK14841  82 EMELLRRERVRVRILGRKEGLPEKVLKKWQEVEEKTKEFDRMTLVIAFNYGGRREILDAVESILKDVSQGK--------K 153

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 738993273 167 EYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGKTGN 245
Cdd:PRK14841 154 IELTEETFRQYLYLPDVPDPDLIIRTSGEMRLSNFLLWQSAYSELYFFKKLWPDFTKRDFLRAIESYSKRERRFGGLIN 232
PRK14828 PRK14828
undecaprenyl pyrophosphate synthase; Provisional
 1-242 7.72e-72

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 237825  Cd Length: 256  Bit Score: 220.39  E-value: 7.72e-72
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   1 MEKTLDMTRIPEHIAIIMDGNGRWAQKRNLPR-TEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLM 79
Cdd:PRK14828  17 LLGELDGAQVPGHVGIIVDGNRRWARKAGFTDvSQGHRAGAAKIGEFLGWCDETDVNVVTLYLLSTDNLGRPSEELNPLL 96

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  80 GlVLSSLEDEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNiq 159
Cdd:PRK14828  97 D-IIEDVVRQLAPDGRWRVRHVGSLDLLPAPSANRLKEAEEATVGNDGIKVNVAVGYGGRQEIVDAVRSLLTEHKDKG-- 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 160 LTADNIKEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRR 239
Cdd:PRK14828 174 TSIDELAESVTVDAISTHLYTGGQPDPDLVIRTSGEQRLSGFMLWQSAHSEYYFCETYWPAFRKVDFLRALRDYSQRERR 253


                 ...
gi 738993273 240 FGK 242
Cdd:PRK14828 254 FGK 256
PRK14827 PRK14827
undecaprenyl pyrophosphate synthase; Provisional
 9-242 2.16e-68

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173288  Cd Length: 296  Bit Score: 212.89  E-value: 2.16e-68
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   9 RIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVrrITKACG--ELGVKYLTLYTFSTENWNRPSEEVSTLMGLV--LS 84
Cdd:PRK14827  66 RLPNHVAIVMDGNGRWATQRGLARTEGHKMGEAVV--IDIACGaiELGIKWLSLYAFSTENWKRSPEEVRFLMGFNrdVV 143

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  85 SLEDEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQltadn 164
Cdd:PRK14827 144 RRRRDNLNKMGVRIRWVGSRPRLWRSVINELAIAEEMTKSNDVITINYCVNYGGRTEITEATREIAREAAAGRLN----- 218

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273 165 iKEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14827 219 -PERITESTIARHLQRPDIPDVDLFLRTSGEQRSSNFMLWQAAYAEYIFQDKLWPDYDRRDLWAACEEYASRNRRFGS 295
PRK14835 PRK14835
isoprenyl transferase;
9-242 1.35e-67

isoprenyl transferase;


Pssm-ID: 237830  Cd Length: 275  Bit Score: 210.08  E-value: 1.35e-67
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   9 RIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSLE- 87
Cdd:PRK14835  40 KLPRHLGLILDGNRRFARALGLQREMGHEFGVQKAYEVLEWCLELGIPTVTIWVFSTDNFSRSPAEVETLMNLFEREARr 119

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  88 ---DEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNiqLTADN 164
Cdd:PRK14835 120 mavDPRIHANRVRVRAIGRHDGFPPKVLEALEELEERTEGHEGMLLNIAVGYGGREEIVDAVKSLLLEAAATG--KSPEE 197

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 738993273 165 IKEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14835 198 VAAELTPEHISAHLYTAGVPDPDFIIRTSGEIRLSGFLLWQSAYSEYYFCDVYWPGFRKVDFLRALRDYQGRERRFGR 275
PRK14842 PRK14842
undecaprenyl pyrophosphate synthase; Provisional
 5-241 5.40e-66

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173303  Cd Length: 241  Bit Score: 204.84  E-value: 5.40e-66
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273   5 LDMTRIPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLS 84
Cdd:PRK14842   3 LFESTIPAHIAVIMDGNGRWAESQGKKRSEGHREGANAIDRLMDASLEYGLKNISLYAFSTENWKRPITEIRSIFGLLVE 82

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  85 SLE---DEIFMKNdARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALELQQQNIQLt 161
Cdd:PRK14842  83 FIEtrlDTIHARG-IRIHHSGSRKKLTRTVLDKIDFAMAKTKKNKNLTVNFCLNYGSHDELLRAAQEVFLARKAKKVTL- 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 162 adniKEYITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFG 241
Cdd:PRK14842 161 ----EKPLKEKEFEKFLYTSPLPPVDLLIRTAGEQRLSNFLLWQSAYAELYFTDTLWPDFDKNSLVDSLKWYETRTRKFG 236
PRK14837 PRK14837
undecaprenyl pyrophosphate synthase; Provisional
 10-242 1.85e-61

undecaprenyl pyrophosphate synthase; Provisional


Pssm-ID: 173298  Cd Length: 230  Bit Score: 193.12  E-value: 1.85e-61
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  10 IPEHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGLVLSSL--E 87
Cdd:PRK14837   6 LPSHVGIIMDGNRRWALKKGLSFFEGHKEGLKRAKEIVKHSLKLGIKYLSLYVFSTENWNRTDSEIEHLMFLIADYLssE 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  88 DEIFMKNDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIAlelqQQNIQLtadnikE 167
Cdd:PRK14837  86 FNFYKKNNIKIIVSGDIESLSEEVKKSIKDAISFTKNFDGLVLNLAINYGGRNEIVRAVKKFL----SSGLDL------E 155

                        170       180       190       200       210       220       230
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 738993273 168 YITEDTISKHLTTAFMPEPDLLIRTGGELRISNYLLWQIAYSELYFCDTFWPDFSEKDLHQAIADYQRRQRRFGK 242
Cdd:PRK14837 156 TLNENVFSKFLDNPELPDLDLLIRTGGDMRISNFLLWRIAYCEFIFSNVLWPEYYVNHYSKDLECFKNRKRNFGR 230
PTZ00349 PTZ00349
dehydrodolichyl diphosphate synthetase; Provisional
 12-222 1.35e-29

dehydrodolichyl diphosphate synthetase; Provisional


Pssm-ID: 185571  Cd Length: 322  Bit Score: 113.17  E-value: 1.35e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  12 EHIAIIMDGNGRWAQKRNLPRTEGHKAGVETVRRITKACGELGVKYLTLYTFSTENWNRPSEEVSTLMGL-VLSSLEDEI 90
Cdd:PTZ00349  21 KHISIIMDGNRRFAKEKGLHSAIGHFMGSKALIQIIEICIKLKIKILSVFSFSLLNYNRSPEEIHFLFYLnLLILINEDF 100

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273  91 FMK----NDARLQVIGDIERLPKEVQTALQQTINNTKNNKSLTLVVALSYSSRWEITKATQDIALE-------LQQQNIQ 159
Cdd:PTZ00349 101 FFKfikdNKIKIKIIGNLSYINDAYRKIIHDIEEKTENFDNILLNIFFSYTSRNEMSLCKFNPNLYfdtyknlLEEKKIL 180

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 738993273 160 LTADNIKEYITEDTIS-------------------------------------------------KHLTTAFMPEPDLLI 190
Cdd:PTZ00349 181 CGSNILTDPIKEGTFAipddedecdyldheleneridldlkfdgdcicgeksflneeqieivnyhKKLLTSDLPPPNILI 260

                        250       260       270
                 ....*....|....*....|....*....|...
gi 738993273 191 RTGGELRISNYLLWQIA-YSELYFCDTFWPDFS 222
Cdd:PTZ00349 261 RTSGEKRLSDFMLYQISeFTEIYFINEYWPIFN 293
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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