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Conserved domains on  [gi|733386797|ref|YP_009112314|]
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NADH dehydrogenase subunit 6 (mitochondrion) [Sarcophaga africa]

Protein Classification

NADH dehydrogenase subunit 6( domain architecture ID 10009599)

NADH dehydrogenase subunit 6 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that functions in the transfer of electrons from NADH to the respiratory chain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 3-173 8.37e-40

NADH dehydrogenase subunit 6; Provisional


:

Pssm-ID: 214445  Cd Length: 160  Bit Score: 132.24  E-value: 8.37e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   3 QWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSFSI 82
Cdd:MTH00166   1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  83 KLMITSIIMFLLSVAILFFIDKNIltqysnmeiksIFDMNSYITENSMSLMKLYNYPNNLLTIMLMNYLLITLIAVVKIT 162
Cdd:MTH00166  81 KLLILFLLMLLLMLNNFIKNSEMS-----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKIT 149

                        170
                 ....*....|.
gi 733386797 163 KLFKGPLRPMF 173
Cdd:MTH00166 150 NIFKGPLRSKN 160
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 3-173 8.37e-40

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 132.24  E-value: 8.37e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   3 QWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSFSI 82
Cdd:MTH00166   1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  83 KLMITSIIMFLLSVAILFFIDKNIltqysnmeiksIFDMNSYITENSMSLMKLYNYPNNLLTIMLMNYLLITLIAVVKIT 162
Cdd:MTH00166  81 KLLILFLLMLLLMLNNFIKNSEMS-----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKIT 149

                        170
                 ....*....|.
gi 733386797 163 KLFKGPLRPMF 173
Cdd:MTH00166 150 NIFKGPLRSKN 160
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
15-161 2.54e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 36.33  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   15 FIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTFwFSYILFLVFLGGMLVLFIYVTSL--ASNEMFSFSIKLMITSIIMF 92
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEF-LAAVQVLVYVGAIMVLFLFVIMLllAEEEPEKLRSGLPLAALLLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 733386797   93 LLSVAILFFIdknILTQYSNMEIKSIFDMNSYITENSMSLMKLYNYPNNLLTIMlmnyLLITLIAVVKI 161
Cdd:pfam00499  80 LLLLALLLLV---LLSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELASVL----LLVALVGAIVL 141
 
Name Accession Description Interval E-value
ND6 MTH00166
NADH dehydrogenase subunit 6; Provisional
 3-173 8.37e-40

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214445  Cd Length: 160  Bit Score: 132.24  E-value: 8.37e-40
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   3 QWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSFSI 82
Cdd:MTH00166   1 KMMLMMLLLILSIIFLFLNHPLSMGLILIIQTILISLLLGLMMKSFWFSYILFLIFLGGMLVLFIYITSLASNEKFKFSL 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  83 KLMITSIIMFLLSVAILFFIDKNIltqysnmeiksIFDMNSYITENSMSLMKLYNYPNNLLTIMLMNYLLITLIAVVKIT 162
Cdd:MTH00166  81 KLLILFLLMLLLMLNNFIKNSEMS-----------NFNNNFNFFENSFSLSKLYNFPTMLITLFMIIYLLLTLIVVVKIT 149

                        170
                 ....*....|.
gi 733386797 163 KLFKGPLRPMF 173
Cdd:MTH00166 150 NIFKGPLRSKN 160
ND6 MTH00152
NADH dehydrogenase subunit 6; Provisional
 1-170 4.82e-13

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214437  Cd Length: 163  Bit Score: 63.37  E-value: 4.82e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   1 MMQWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGlMTKTFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSF 80
Cdd:MTH00152   1 MSLMILLSVCFSLFLLLPLSKQPLSLGLVLLLLSLFVCVEIG-LTLSSWYGYLLFLVYVGGLLVMFAYVVSLSPNPLFGS 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  81 SIKLMITSIIMFLLSVAILFFIdkniltQYSNMEIKSIFDMNSYITENSMSLMKLYNYPNNLLTIMLMNYLLITLIAVVK 160
Cdd:MTH00152  80 NFKFVFFSLTLFGFLGLFFFFL------YLYSSGGLSLSSLFDGSSGSLSFGGGLYSSSGWSIFVFLAVLLLIVMVSVVK 153

                        170
                 ....*....|
gi 733386797 161 ITKLFKGPLR 170
Cdd:MTH00152 154 ICYYEEGSLR 163
ND6 MTH00212
NADH dehydrogenase subunit 6; Provisional
 1-173 2.07e-12

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 214460  Cd Length: 160  Bit Score: 61.56  E-value: 2.07e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   1 MMQWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGLMTkTFWFSYILFLVFLGGMLVLFIYVTSLASNEMFSF 80
Cdd:MTH00212   1 MLLSLLLSLLLLLMLLFPLSAHPLTLGVSLLLSSLLSCLIITMES-NSWYGYILFLIYIGGLLVLFGYMVALSPNEHLFF 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  81 SIKLMitsiiMFLLSVAILFFIDKNILTQYSNMEIKSIFDMNSYItensmslMKLYNYPNNLLTIMLMNYLLITLIAVVK 160
Cdd:MTH00212  80 KKYFK-----GFGMILISLNLYLLLMTLGSSNFSPMLNLKLELNV-------SKILSNNNIPILLFLGLILLIALLMVVK 147

                        170
                 ....*....|...
gi 733386797 161 ITKLFKGPLRPMF 173
Cdd:MTH00212 148 ICQYYKGPLRPFL 160
ND6 MTH00138
NADH dehydrogenase subunit 6; Provisional
 51-74 1.60e-03

NADH dehydrogenase subunit 6; Provisional


Pssm-ID: 177196  Cd Length: 173  Bit Score: 37.43  E-value: 1.60e-03
                         10        20
                 ....*....|....*....|....
gi 733386797  51 SYILFLVFLGGMLVLFIYVTSLAS 74
Cdd:MTH00138  52 SLVLFLIYLGGMLVVFAYSAALAA 75
Oxidored_q3 pfam00499
NADH-ubiquinone/plastoquinone oxidoreductase chain 6;
15-161 2.54e-03

NADH-ubiquinone/plastoquinone oxidoreductase chain 6;


Pssm-ID: 459832 [Multi-domain]  Cd Length: 141  Bit Score: 36.33  E-value: 2.54e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   15 FIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTFwFSYILFLVFLGGMLVLFIYVTSL--ASNEMFSFSIKLMITSIIMF 92
Cdd:pfam00499   1 LGVVTSRNPVHSALFLVLTFFGVAGLYLLLGAEF-LAAVQVLVYVGAIMVLFLFVIMLllAEEEPEKLRSGLPLAALLLG 79

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 733386797   93 LLSVAILFFIdknILTQYSNMEIKSIFDMNSYITENSMSLMKLYNYPNNLLTIMlmnyLLITLIAVVKI 161
Cdd:pfam00499  80 LLLLALLLLV---LLSASLTPAAAAAAPDVGNIEAIGELLFTDYLLPFELASVL----LLVALVGAIVL 141
ND6 MTH00015
NADH dehydrogenase subunit 6; Validated
 1-171 2.93e-03

NADH dehydrogenase subunit 6; Validated


Pssm-ID: 164590  Cd Length: 155  Bit Score: 36.37  E-value: 2.93e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797   1 MMQWILMTLLIIFNFIFFNMKHPLAMGLTLLIQTTLICLTSGLMTKTfWFSYILFLVFLGGMLVLFIYVTSLASNEMFSF 80
Cdd:MTH00015   1 MSLSFFLILMISLTCSLFLATTPITLGINILMMALLLATTMASALSS-WFAFLTFLIYVGGMLVMFAYFLALTPNQQLNL 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 733386797  81 SIKLMITSIIMFLLSVAILFFidkniltqysNMEIKSIFDMnsyitenSMSLMKLYNYPNNLLTIMLMNYLLITLIAVVK 160
Cdd:MTH00015  80 GPMAKYTLITLLTLSTTLKLT----------NPPSPSFFSS-------TQGNTFLYQPENAPLLIFLALILLLTMVIVVK 142

                        170
                 ....*....|.
gi 733386797 161 ITKLFKGPLRP 171
Cdd:MTH00015 143 LTRRSSGPLRP 153
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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