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Conserved domains on  [gi|719982495|ref|XP_010250467|]
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PREDICTED: ALBINO3-like protein 2, chloroplastic isoform X2 [Nelumbo nucifera]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
 167-312 1.51e-33

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


:

Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 126.10  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 167 FRTERHAIGCPSYLWFLASF---SVQVPCFLLWMTSVRRMSLDHHPGFDCGGILWFQNLTELPHGVfgsIFPILIASLHF 243
Cdd:cd20069   62 ARKELKELMKKHNVNPLKSLllpLVQAPVFISFFFALRKMANLPVPSFKTGGLLWFTDLTVPDPYY---ILPILTSLTFL 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 719982495 244 MNVQISFRTSTVGKATglfgllAKYYKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNHP 312
Cdd:cd20069  139 ATIELGAETGTSGSPQ------SKTMKNVFRGLPVLMIPFTANFPSAVFLYWITSNLFSLAQNLLLRIP 201
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 359-512 3.28e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


:

Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 81.01  E-value: 3.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLil 438
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL-----DPDEPEARLNL-- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 719982495 439 ssswaGVTYIRQGRNEEGIEHLERIAKLkEPEDPKCKAHYFDgllllasALLNEGRKSEAEKLLQMAAAYNPAY 512
Cdd:COG4783   79 -----GLALLKAGDYDEALALLEKALKL-DPEHPEAYLRLAR-------AYRALGRPDEAIAALEKALELDPDD 139
 
Name Accession Description Interval E-value
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
 167-312 1.51e-33

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 126.10  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 167 FRTERHAIGCPSYLWFLASF---SVQVPCFLLWMTSVRRMSLDHHPGFDCGGILWFQNLTELPHGVfgsIFPILIASLHF 243
Cdd:cd20069   62 ARKELKELMKKHNVNPLKSLllpLVQAPVFISFFFALRKMANLPVPSFKTGGLLWFTDLTVPDPYY---ILPILTSLTFL 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 719982495 244 MNVQISFRTSTVGKATglfgllAKYYKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNHP 312
Cdd:cd20069  139 ATIELGAETGTSGSPQ------SKTMKNVFRGLPVLMIPFTANFPSAVFLYWITSNLFSLAQNLLLRIP 201
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 359-512 3.28e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 81.01  E-value: 3.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLil 438
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL-----DPDEPEARLNL-- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 719982495 439 ssswaGVTYIRQGRNEEGIEHLERIAKLkEPEDPKCKAHYFDgllllasALLNEGRKSEAEKLLQMAAAYNPAY 512
Cdd:COG4783   79 -----GLALLKAGDYDEALALLEKALKL-DPEHPEAYLRLAR-------AYRALGRPDEAIAALEKALELDPDD 139
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 356-470 6.18e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 6.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  356 SPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAiSKLlivghptDDENIDL 435
Cdd:TIGR02917 328 SHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKA-TEL-------DPENAAA 399

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 719982495  436 lilsSSWAGVTYIRQGRNEEGIEHLERIAKLkEPE 470
Cdd:TIGR02917 400 ----RTQLGISKLSQGDPSEAIADLETAAQL-DPE 429
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 359-418 3.86e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.78  E-value: 3.86e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAI 418
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAI 61
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 188-307 1.19e-05

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 45.94  E-value: 1.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  188 VQVPCFL-LWMTSVRRMSLDHHPgfdcggILWFQNLTeLPHGVFgsIFPILIASLHFMNVQISFRTSTVGKATglfglla 266
Cdd:TIGR03592  76 IQMPIFIaLYQVLLRSIELRHAP------FLWIIDLS-SPDPYY--ILPILMGVTMFLQQKLSPKGPPDPAQQ------- 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 719982495  267 kyyKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQL 307
Cdd:TIGR03592 140 ---KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQL 177
60KD_IMP pfam02096
60Kd inner membrane protein;
188-311 2.22e-05

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 45.15  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  188 VQVPCFL-LWMTsVRRMS-LDHHPGFdcggiLWFQNLTE--LPHGVFGSIFPILIASLHFMNVQISFRTSTVGKAtglfg 263
Cdd:pfam02096  75 IQMPIFIaLYRV-LRNSIeLRHAPFF-----LWIADLSApdPISILHYYILPILMGVTMFLQQKLTPAPQDQPPQ----- 143

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 719982495  264 llAKYYKLYlqILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNH 311
Cdd:pfam02096 144 --MKMMMLY--FMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 361-462 7.48e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.19  E-value: 7.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 361 LALsiQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAIskllivghptdDENIDLL---- 436
Cdd:PRK11788 186 LAQ--QALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVE-----------EQDPEYLsevl 252

                         90       100
                 ....*....|....*....|....*..
gi 719982495 437 -ILSSSwagvtYIRQGRNEEGIEHLER 462
Cdd:PRK11788 253 pKLMEC-----YQALGDEAEGLEFLRR 274
TPR_19 pfam14559
Tetratricopeptide repeat;
371-420 3.57e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 3.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 719982495  371 GDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISK 420
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAA 51
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
270-312 4.09e-03

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 38.56  E-value: 4.09e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 719982495 270 KLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNHP 312
Cdd:COG0706  165 KKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRR 207
 
Name Accession Description Interval E-value
5TM_Oxa1-like cd20069
Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar ...
 167-312 1.51e-33

Five transmembrane core domain of mitochondrial inner membrane protein Oxa1 and similar proteins; This group is composed mostly of the mitochondrial members of the YidC/Oxa1/Alb3 protein family of insertases, including mitochondrial inner membrane proteins Oxa1, Oxa1-like (Oxa1L), cytochrome c oxidase assembly protein 18 (Cox18, also called Oxa2), and Arabidopsis thaliana mitochondrial ALBINO3-like protein 3 (ALB33). It also includes Arabidopsis thaliana chloroplastic ALBINO3-like protein 2 (ALB32). Members of this group mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Oxa1 and Cox18/Oxa2 are essential for the activity and assembly of cytochrome c oxidase, playing central roles in the translocation and export of the N-terminal and C-terminal parts, respectively, of the COX2 protein into the mitochondrial intermembrane space. ALB32 may be involved in the insertion of integral membrane proteins into the chloroplast thylakoid membranes. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410993 [Multi-domain]  Cd Length: 201  Bit Score: 126.10  E-value: 1.51e-33
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 167 FRTERHAIGCPSYLWFLASF---SVQVPCFLLWMTSVRRMSLDHHPGFDCGGILWFQNLTELPHGVfgsIFPILIASLHF 243
Cdd:cd20069   62 ARKELKELMKKHNVNPLKSLllpLVQAPVFISFFFALRKMANLPVPSFKTGGLLWFTDLTVPDPYY---ILPILTSLTFL 138

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 719982495 244 MNVQISFRTSTVGKATglfgllAKYYKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNHP 312
Cdd:cd20069  139 ATIELGAETGTSGSPQ------SKTMKNVFRGLPVLMIPFTANFPSAVFLYWITSNLFSLAQNLLLRIP 201
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 359-512 3.28e-18

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 81.01  E-value: 3.28e-18
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLil 438
Cdd:COG4783    6 ALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALEL-----DPDEPEARLNL-- 78

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 719982495 439 ssswaGVTYIRQGRNEEGIEHLERIAKLkEPEDPKCKAHYFDgllllasALLNEGRKSEAEKLLQMAAAYNPAY 512
Cdd:COG4783   79 -----GLALLKAGDYDEALALLEKALKL-DPEHPEAYLRLAR-------AYRALGRPDEAIAALEKALELDPDD 139
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 375-517 2.74e-16

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 75.43  E-value: 2.74e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 375 RAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAIsKLlivghptDDENIDLLILssswAGVTYIRQGRNE 454
Cdd:COG4235    1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKAL-RL-------DPDNADALLD----LAEALLAAGDTE 68

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 719982495 455 EGIEHLERIAKLkEPEDPkcKAHYFDGllllaSALLNEGRKSEAEKLLQMAAAYNPAYNEYLQ 517
Cdd:COG4235   69 EAEELLERALAL-DPDNP--EALYLLG-----LAAFQQGDYAEAIAAWQKLLALLPADAPARL 123
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
360-516 1.34e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.50  E-value: 1.34e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 360 LLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLils 439
Cdd:COG0457   11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL-----DPDDAEALNNL--- 82

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 719982495 440 sswaGVTYIRQGRNEEGIEHLERIAKLkEPEDPkcKAHYFDGllllaSALLNEGRKSEAEKLLQMAAAYNPAYNEYL 516
Cdd:COG0457   83 ----GLALQALGRYEEALEDYDKALEL-DPDDA--EALYNLG-----LALLELGRYDEAIEAYERALELDPDDADAL 147
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
360-518 1.96e-14

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 73.12  E-value: 1.96e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 360 LLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLils 439
Cdd:COG0457   45 LYNLGLAYLRLGRYEEALADYEQALELDPDDAEALNNLGLALQALGRYEEALEDYDKALEL-----DPDDAEALYNL--- 116

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 719982495 440 sswaGVTYIRQGRNEEGIEHLERIAKLkEPEDPkcKAHYFDGLLLLASallneGRKSEAEKLLQMAAAYNPAYNEYLQQ 518
Cdd:COG0457  117 ----GLALLELGRYDEAIEAYERALEL-DPDDA--DALYNLGIALEKL-----GRYEEALELLEKLEAAALAALLAAAL 183
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 360-478 1.56e-13

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 73.10  E-value: 1.56e-13
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 360 LLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivghptDDENIDLLils 439
Cdd:COG3914  115 LFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALEL--------DPDNAEAL--- 183

                         90       100       110
                 ....*....|....*....|....*....|....*....
gi 719982495 440 sSWAGVTYIRQGRNEEGIEHLERIAKLKePEDPKCKAHY 478
Cdd:COG3914  184 -NNLGNALQDLGRLEEAIAAYRRALELD-PDNADAHSNL 220
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 333-516 2.56e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.45  E-value: 2.56e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 333 GNLEKLeIRSLDTLVKNNSVKSLSpyeLLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIE 412
Cdd:COG2956   56 GEYDRA-IRIHQKLLERDPDRAEA---LLELAQDYLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIE 131

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 413 HFEHAISKllivghptDDENIDLLILssswAGVTYIRQGRNEEGIEHLERIAKLkepeDPKC-KAHYFDGllllaSALLN 491
Cdd:COG2956  132 VLERLLKL--------GPENAHAYCE----LAELYLEQGDYDEAIEALEKALKL----DPDCaRALLLLA-----ELYLE 190

                        170       180
                 ....*....|....*....|....*
gi 719982495 492 EGRKSEAEKLLQMAAAYNPAYNEYL 516
Cdd:COG2956  191 QGDYEEAIAALERALEQDPDYLPAL 215
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 330-467 2.68e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.06  E-value: 2.68e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 330 ETSGNLEKLeIRSLDTLVKNNSVkslSPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLE 409
Cdd:COG2956  121 EQEGDWEKA-IEVLERLLKLGPE---NAHAYCELAELYLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEE 196

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 719982495 410 AIEHFEHAISKllivghptDDENIDLLILssswAGVTYIRQGRNEEGIEHLERIAKLK 467
Cdd:COG2956  197 AIAALERALEQ--------DPDYLPALPR----LAELYEKLGDPEEALELLRKALELD 242
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 358-472 3.55e-12

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 63.49  E-value: 3.55e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 358 YELLALSiqLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivghptDDENIDLLI 437
Cdd:COG4235   20 WLLLGRA--YLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALAL--------DPDNPEALY 89

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 719982495 438 LssswAGVTYIRQGRNEEGIEHLERIAKLKEPEDP 472
Cdd:COG4235   90 L----LGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 359-518 4.51e-12

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 68.48  E-value: 4.51e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivghptDDENIDLLIL 438
Cdd:COG3914   80 LLELAALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALAL--------NPDFAEAYLN 151

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 439 SsswaGVTYIRQGRNEEGIEHLERIAKLKePEDPkcKAHYfdgllLLASALLNEGRKSEAEKLLQMAAAYNPAYNEYLQQ 518
Cdd:COG3914  152 L----GEALRRLGRLEEAIAALRRALELD-PDNA--EALN-----NLGNALQDLGRLEEAIAAYRRALELDPDNADAHSN 219
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 333-516 1.35e-11

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 65.14  E-value: 1.35e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 333 GNLEKLEiRSLDTLVKNNSvKSLSPYELLALSiqLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIE 412
Cdd:COG2956   90 GLLDRAE-ELLEKLLELDP-DDAEALRLLAEI--YEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAIE 165

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 413 HFEHAISKllivghptDDENIDLLILssswAGVTYIRQGRNEEGIEHLERIAKLkepeDPKckahYFDGLLLLASALLNE 492
Cdd:COG2956  166 ALEKALKL--------DPDCARALLL----LAELYLEQGDYEEAIAALERALEQ----DPD----YLPALPRLAELYEKL 225

                        170       180
                 ....*....|....*....|....
gi 719982495 493 GRKSEAEKLLQMAAAYNPAYNEYL 516
Cdd:COG2956  226 GDPEEALELLRKALELDPSDDLLL 249
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 361-516 1.22e-10

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 62.44  E-value: 1.22e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 361 LALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivghptDDENIDLLILss 440
Cdd:COG2956   12 YFKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDRAIRIHQKLLER--------DPDRAEALLE-- 81

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 719982495 441 swAGVTYIRQGRNEEGIEHLERIAKLkEPEDPKCKAHYFDgllllasALLNEGRKSEAEKLLQMAAAYNPAYNEYL 516
Cdd:COG2956   82 --LAQDYLKAGLLDRAEELLEKLLEL-DPDDAEALRLLAE-------IYEQEGDWEKAIEVLERLLKLGPENAHAY 147
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 367-466 3.70e-10

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 58.43  E-value: 3.70e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 367 LLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLilssswaGVT 446
Cdd:COG5010   64 YNKLGDFEESLALLEQALQLDPNNPELYYNLALLYSRSGDKDEAKEYYEKALAL-----SPDNPNAYSNL-------AAL 131

                         90       100
                 ....*....|....*....|
gi 719982495 447 YIRQGRNEEGIEHLERIAKL 466
Cdd:COG5010  132 LLSLGQDDEAKAALQRALGT 151
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
367-467 4.82e-10

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 56.33  E-value: 4.82e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 367 LLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEhFEHAISKllivgHPTDDENIDLLilssswaGVT 446
Cdd:COG3063    2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDEAIA-LEKALKL-----DPNNAEALLNL-------AEL 68

                         90       100
                 ....*....|....*....|.
gi 719982495 447 YIRQGRNEEGIEHLERIAKLK 467
Cdd:COG3063   69 LLELGDYDEALAYLERALELD 89
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 365-465 2.90e-08

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 51.92  E-value: 2.90e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 365 IQLLTKGDKDRAIALLRMALEKDPE---YIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLIlsss 441
Cdd:COG1729    1 KALLKAGDYDEAIAAFKAFLKRYPNsplAPDALYWLGEAYYALGDYDEAAEAFEKLLKR-----YPDSPKAPDALL---- 71

                         90       100
                 ....*....|....*....|....
gi 719982495 442 WAGVTYIRQGRNEEGIEHLERIAK 465
Cdd:COG1729   72 KLGLSYLELGDYDKARATLEELIK 95
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
384-516 9.09e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 53.09  E-value: 9.09e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 384 LEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivghptDDENIDLLilssSWAGVTYIRQGRNEEGIEHLERI 463
Cdd:COG0457    1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL--------DPDDAEAL----YNLGLAYLRLGRYEEALADYEQA 68

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|...
gi 719982495 464 AKLkEPEDPkcKAHYFDGllllaSALLNEGRKSEAEKLLQMAAAYNPAYNEYL 516
Cdd:COG0457   69 LEL-DPDDA--EALNNLG-----LALQALGRYEEALEDYDKALELDPDDAEAL 113
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
363-462 1.42e-07

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 52.22  E-value: 1.42e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 363 LSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLILSSS- 441
Cdd:COG4785  113 RGLAYLLLGDYDAALEDFDRALELDPDYAYAYLNRGIALYYLGRYELAIADLEKALEL-----DPNDPERALWLYLAERk 187

                         90       100       110
                 ....*....|....*....|....*....|....
gi 719982495 442 -------------WAGVtYIRQGRNEEGIEHLER 462
Cdd:COG4785  188 ldpekalallledWATA-YLLQGDTEEARELFKL 220
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 338-510 1.95e-07

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 50.73  E-value: 1.95e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 338 LEIRSLDTLVKNNSVKSLSPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHA 417
Cdd:COG5010    1 ARALEGFDRLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 418 ISKllivgHPTDDENIDLLilssswaGVTYIRQGRNEEGIEHLERIAKLKePEDPKCKAHYfdgllllASALLNEGRKSE 497
Cdd:COG5010   81 LQL-----DPNNPELYYNL-------ALLYSRSGDKDEAKEYYEKALALS-PDNPNAYSNL-------AALLLSLGQDDE 140

                        170
                 ....*....|...
gi 719982495 498 AEKLLQMAAAYNP 510
Cdd:COG5010  141 AKAALQRALGTSP 153
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 356-470 6.18e-07

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 52.39  E-value: 6.18e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  356 SPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAiSKLlivghptDDENIDL 435
Cdd:TIGR02917 328 SHQARRLLASIQLRLGRVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKA-TEL-------DPENAAA 399

                          90       100       110
                  ....*....|....*....|....*....|....*
gi 719982495  436 lilsSSWAGVTYIRQGRNEEGIEHLERIAKLkEPE 470
Cdd:TIGR02917 400 ----RTQLGISKLSQGDPSEAIADLETAAQL-DPE 429
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 358-518 1.04e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 51.53  E-value: 1.04e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 358 YELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISKllivgHPTDDENIDLLi 437
Cdd:COG3914   45 LLLLAALAEAAAAALLALAAGEAAAAAAALLLLAALLELAALLLQALGRYEEALALYRRALAL-----NPDNAEALFNL- 118

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 438 lssswaGVTYIRQGRNEEGIEHLERIAKLKePEDPkcKAHYFDGllllaSALLNEGRKSEAEKLLQMAAAYNPAYNEYLQ 517
Cdd:COG3914  119 ------GNLLLALGRLEEALAALRRALALN-PDFA--EAYLNLG-----EALRRLGRLEEAIAALRRALELDPDNAEALN 184


                 .
gi 719982495 518 Q 518
Cdd:COG3914  185 N 185
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 343-522 2.81e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 50.08  E-value: 2.81e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  343 LDTLVKNnsvkslSPYELLALSIQLLT---KGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFE---- 415
Cdd:TIGR02917 250 ADALLKK------APNSPLAHYLKALVdfqKKNYEDARETLQDALKSAPEYLPALLLAGASEYQLGNLEQAYQYLNqilk 323

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  416 -----HAISKLLIV-----GHPTDDENI----------DLLILSSswAGVTYIRQGRNEEGIEHLERIAKLkepeDPKCK 475
Cdd:TIGR02917 324 yapnsHQARRLLASiqlrlGRVDEAIATlspalgldpdDPAALSL--LGEAYLALGDFEKAAEYLAKATEL----DPENA 397

                         170       180       190       200       210
                  ....*....|....*....|....*....|....*....|....*....|....*
gi 719982495  476 AHYfdglLLLASALLNEGRKSEAEKLLQMAAAYNPAYNE--------YLQQCRED 522
Cdd:TIGR02917 398 AAR----TQLGISKLSQGDPSEAIADLETAAQLDPELGRadlllilsYLRSGQFD 448
ACL4-like cd24142
Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 ...
 359-418 3.86e-06

Assembly chaperone of ribosomal protein L4 and similar proteins; Assembly chaperone of RPL4 (ACL4) acts as a chaperone for the L4 ribosomal subunit, encoded by RPL4A and RPL4B, and is required for hierarchical ribosome assembly. It is required for the soluble expression of newly synthesized RPL4 and for the protection of RPL4 from the Tom1-dependent cellular degradation machinery. ACL4 shields ribosomal protein L4 until timely release and insertion into the pre-ribosome is possible, once ribosomal protein L18 is present.


Pssm-ID: 467942 [Multi-domain]  Cd Length: 306  Bit Score: 48.78  E-value: 3.86e-06
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAI 418
Cdd:cd24142    2 ELLEKAEELLDQGNFELALKFLQRALELEPNNVEALELLGEILLELGDVEEAREVLLRAI 61
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
370-472 4.85e-06

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 47.60  E-value: 4.85e-06
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 370 KGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAIsKLlivgHPTDDENIDLLilssswaGVTYIR 449
Cdd:COG4785   86 LGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRAL-EL----DPDYAYAYLNR-------GIALYY 153

                         90       100
                 ....*....|....*....|...
gi 719982495 450 QGRNEEGIEHLERIAKLKePEDP 472
Cdd:COG4785  154 LGRYELAIADLEKALELD-PNDP 175
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 316-511 9.21e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.54  E-value: 9.21e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  316 NKLGLPEKDALVKSETSG----NLEKLEiRSLDTLVKNNSVKSLSPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYI 391
Cdd:TIGR02917 115 GKTLLDDEGAAELLALRGlaylGLGQLE-LAQKSYEQALAIDPRSLYAKLGLAQLALAENRFDEARALIDEVLTADPGNV 193

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  392 RALVVLGQTLMQKGLLLEAIEHFEHAIsKLlivgHPtddENIDLLILssswAGVTYIRQGRNEEGIEHLERIAKlKEPED 471
Cdd:TIGR02917 194 DALLLKGDLLLSLGNIELALAAYRKAI-AL----RP---NNIAVLLA----LATILIEAGEFEEAEKHADALLK-KAPNS 260

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 719982495  472 PkcKAHYFDGLLLLASALLNEGRkSEAEKLLQMAAAYNPA 511
Cdd:TIGR02917 261 P--LAHYLKALVDFQKKNYEDAR-ETLQDALKSAPEYLPA 297
yidC_oxa1_cterm TIGR03592
membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes ...
 188-307 1.19e-05

membrane protein insertase, YidC/Oxa1 family, C-terminal domain; This model describes full-length from some species, and the C-terminal region only from other species, of the YidC/Oxa1 family of proteins. This domain appears to be univeral among bacteria (although absent from Archaea). The well-characterized YidC protein from Escherichia coli and its close homologs contain a large N-terminal periplasmic domain in addition to the region modeled here. [Protein fate, Protein and peptide secretion and trafficking]


Pssm-ID: 274665 [Multi-domain]  Cd Length: 179  Bit Score: 45.94  E-value: 1.19e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  188 VQVPCFL-LWMTSVRRMSLDHHPgfdcggILWFQNLTeLPHGVFgsIFPILIASLHFMNVQISFRTSTVGKATglfglla 266
Cdd:TIGR03592  76 IQMPIFIaLYQVLLRSIELRHAP------FLWIIDLS-SPDPYY--ILPILMGVTMFLQQKLSPKGPPDPAQQ------- 139

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|.
gi 719982495  267 kyyKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQL 307
Cdd:TIGR03592 140 ---KMMMYFMPLMFLFFFLSFPAGLVLYWVVSNLFTIIQQL 177
60KD_IMP pfam02096
60Kd inner membrane protein;
188-311 2.22e-05

60Kd inner membrane protein;


Pssm-ID: 460443 [Multi-domain]  Cd Length: 187  Bit Score: 45.15  E-value: 2.22e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  188 VQVPCFL-LWMTsVRRMS-LDHHPGFdcggiLWFQNLTE--LPHGVFGSIFPILIASLHFMNVQISFRTSTVGKAtglfg 263
Cdd:pfam02096  75 IQMPIFIaLYRV-LRNSIeLRHAPFF-----LWIADLSApdPISILHYYILPILMGVTMFLQQKLTPAPQDQPPQ----- 143

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|....*...
gi 719982495  264 llAKYYKLYlqILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNH 311
Cdd:pfam02096 144 --MKMMMLY--FMPLMFLFFFLNFPAGLVLYWVVSNLLSIGQQLIINR 187
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 356-466 3.58e-05

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 46.62  E-value: 3.58e-05
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  356 SPYELLAlsIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISkllivghpTDDENIDL 435
Cdd:TIGR02917 466 SLHNLLG--AIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLT--------IDPKNLRA 535

                          90       100       110
                  ....*....|....*....|....*....|.
gi 719982495  436 LILSSSwagvTYIRQGRNEEGIEHLERIAKL 466
Cdd:TIGR02917 536 ILALAG----LYLRTGNEEEAVAWLEKAAEL 562
PRK11788 PRK11788
tetratricopeptide repeat protein; Provisional
 361-462 7.48e-05

tetratricopeptide repeat protein; Provisional


Pssm-ID: 236983 [Multi-domain]  Cd Length: 389  Bit Score: 45.19  E-value: 7.48e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 361 LALsiQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAIskllivghptdDENIDLL---- 436
Cdd:PRK11788 186 LAQ--QALARGDLDAARALLKKALAADPQCVRASILLGDLALAQGDYAAAIEALERVE-----------EQDPEYLsevl 252

                         90       100
                 ....*....|....*....|....*..
gi 719982495 437 -ILSSSwagvtYIRQGRNEEGIEHLER 462
Cdd:PRK11788 253 pKLMEC-----YQALGDEAEGLEFLRR 274
5TM_YidC_Oxa1_Alb3 cd19751
Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1 ...
 188-307 1.40e-04

Five transmembrane core domain of YidC/Oxa1/Alb3 protein family of insertases; The YidC/Oxa1/Alb3 protein family of insertases facilitate the insertion, folding and assembly of proteins of the inner membranes of bacteria and mitochondria, and the thylakoid membrane of plastids. Members include bacterial YidC, mitochondrial Cox18 and Oxa1, and chloroplastic Alb3 and Alb4. Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Oxa1 and Cox18/Oxa2 mediate the insertion of both mitochondrion-encoded precursors and nuclear-encoded proteins from the matrix into the mitochondrial inner membrane. Alb3 and Alb3-like proteins, including Alb4, are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410992 [Multi-domain]  Cd Length: 189  Bit Score: 42.93  E-value: 1.40e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 188 VQVPCFLLWMTSVRRMsldhhPGFDCGGILWFQNLTElPHGVFgsIFPILIASLHFMNVQISFRTSTVGKatglfgLLAK 267
Cdd:cd19751   80 IQLPIFMAFYFAIMRT-----EEIRYHTFLWFFDLGQ-PDYLY--ILPFVAGITTYFQFKMTMSHQQQMQ------MMQM 145

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|
gi 719982495 268 YYKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQL 307
Cdd:cd19751  146 QMKVMLYVMPVMIIIAGLSFPSALSLYWIISNLFMIIQTY 185
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 356-511 1.93e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 44.30  E-value: 1.93e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  356 SPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISklliVGHPTDDENIDL 435
Cdd:TIGR02917  21 SPEELIEAAKSYLQKNKYKAAIIQLKNALQKDPNDAEARFLLGKIYLALGDYAAAEKELRKALS----LGYPKNQVLPLL 96

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 719982495  436 LILssswagvtYIRQGRNEEGIEHLERIAKLKEPEDPKCKAHYFDGllllasaLLNEGRKSEAEKLLQMAAAYNPA 511
Cdd:TIGR02917  97 ARA--------YLLQGKFQQVLDELPGKTLLDDEGAAELLALRGLA-------YLGLGQLELAQKSYEQALAIDPR 157
TPR_19 pfam14559
Tetratricopeptide repeat;
371-420 3.57e-04

Tetratricopeptide repeat;


Pssm-ID: 434038 [Multi-domain]  Cd Length: 65  Bit Score: 38.72  E-value: 3.57e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|
gi 719982495  371 GDKDRAIALLRMALEKDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISK 420
Cdd:pfam14559   2 GDYAEALELLEQALAEDPDNAEARLGLAEALLALGRLDEAEALLAALPAA 51
TPR_16 pfam13432
Tetratricopeptide repeat; This family is found predominantly at the C-terminus of ...
 361-415 4.21e-04

Tetratricopeptide repeat; This family is found predominantly at the C-terminus of transglutaminase enzyme core regions.


Pssm-ID: 433202 [Multi-domain]  Cd Length: 68  Bit Score: 38.86  E-value: 4.21e-04
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|....*...
gi 719982495  361 LALSIQLLTKGDKDRAIALLRMALEKD---PEYIRALVVLGQTLMQKGLLLEAIEHFE 415
Cdd:pfam13432   1 LALARAALRAGDYDDAAAALEAALARFpesPDAAAALLLLGLAALRQGRLAEAAAAYR 58
COG4700 COG4700
Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];
395-517 8.81e-04

Uncharacterized conserved protein ECs_4300, contains TPR-like domain [Function unknown];


Pssm-ID: 443735 [Multi-domain]  Cd Length: 249  Bit Score: 41.02  E-value: 8.81e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 395 VVLGQTLMQKGLLLEAIEHFEHAISKLlivgHPTDdenIDLLilsssW-AGVTYIRQGRNEEGIEHLERIAKlkepEDPK 473
Cdd:COG4700   93 VRLADALLELGRYDEAIELYEEALTGI----FADD---PHIL-----LgLAQALFELGRYAEALETLEKLIA----KNPD 156

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 719982495 474 CKAHyfDGLLLLASALLNEGRKSEAEKLLQMAAAYNPAYNEYLQ 517
Cdd:COG4700  157 FKSS--DAHLLYARALEALGDLEAAEAELEALARRYSGPEARYR 198
5TM_YidC_Alb3 cd20070
Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; ...
 188-311 1.22e-03

Five transmembrane core domain of membrane protein insertase YidC, Alb3, and similar proteins; This group is composed of the bacterial and chloroplastic members of the YidC/Oxa1/Alb3 protein family of insertases, including bacterial YidC, and chloroplastic ALBINO3 (Alb3) and Alb3-like proteins such as ALBINO3-like protein 1 (also called Alb4). Membrane protein insertase YidC, also called foldase YidC or membrane integrase YidC, facilitates proper folding, insertion, and assembly of inner membrane proteins and complexes. Depending on the nature of the substrate, YidC functions in a Sec-independent (YidC only) or a Sec-dependent manner as part of a complex containing YidC, the SecYEG channel, and SecDFYajC. YidC from Gram-negative bacteria contains an extra transmembrane segment (TM1) at the N-terminus and a large periplasmic domain, located between TM1 and TM2, that adopts a beta-super sandwich fold that is found in sugar-binding proteins such as galactose mutarotase. Alb3 and Alb3-like proteins are required for the post-translational insertion of the light-harvesting chlorophyll-binding proteins (LHCPs) into the chloroplast thylakoid membrane. Alb3 acts independently and may also function cooperatively with the thylakoid cpSecYE translocase to insert proteins co-translationally into the thylakoid membrane, similar to bacterial YidC that can function with the SecYEG translocase. YidC/Oxa1/Alb3 family insertases contain a core domain of five transmembrane (5TM) segments that is essential to insertase function.


Pssm-ID: 410994 [Multi-domain]  Cd Length: 181  Bit Score: 40.05  E-value: 1.22e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 188 VQVPCFLLWMTSVRRMSLDHHPGFdcggILWFQNLTElPHGVFgsIFPILIASLHFMNVQISFRTSTVGKATGlfgllak 267
Cdd:cd20070   74 IQMPIFIALYQVLRNSIELRGAPF----LWWILDLSA-PDPYY--ILPILMGVTMFLQQKLTPTPTDDQAPQQ------- 139

                         90       100       110       120
                 ....*....|....*....|....*....|....*....|....
gi 719982495 268 yyKLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNH 311
Cdd:cd20070  140 --KMMMYFMPVMFTFIFLSFPSGLVLYWLVSNLFSIIQQLIINK 181
TPR_12 pfam13424
Tetratricopeptide repeat;
389-468 3.02e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 36.60  E-value: 3.02e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495  389 EYIRALVVLGQTLMQKGLLLEAIEHFEHAISKLLIVGHPTDDENIDLLILssswAGVTYIRQGRNEEGIEHLERIAKLKE 468
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLLGPDHPLTATTLLN----LGRLYLELGRYEEALELLERALALAE 76
CpoB COG1729
Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane ...
 340-420 3.44e-03

Cell division protein CpoB, coordinates peptidoglycan biosynthesis and outer membrane constriction [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441335 [Multi-domain]  Cd Length: 113  Bit Score: 37.28  E-value: 3.44e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 340 IRSLDTLVKNNSVKSLSPYELLALSIQLLTKGDKDRAIALLRMALEKDPEYIR---ALVVLGQTLMQKGLLLEAIEHFEH 416
Cdd:COG1729   13 IAAFKAFLKRYPNSPLAPDALYWLGEAYYALGDYDEAAEAFEKLLKRYPDSPKapdALLKLGLSYLELGDYDKARATLEE 92


                 ....
gi 719982495 417 AISK 420
Cdd:COG1729   93 LIKK 96
YidC COG0706
Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];
270-312 4.09e-03

Membrane protein insertase Oxa1/YidC/SpoIIIJ [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 440470 [Multi-domain]  Cd Length: 212  Bit Score: 38.56  E-value: 4.09e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|...
gi 719982495 270 KLYLQILTLPIFVMGYCVPQGSLIYWVTNSSLSVIQQLSLNHP 312
Cdd:COG0706  165 KKMMYIMPLMFLFFFLSFPAGLVLYWVVSNLLTIGQQLIINRR 207
TPR_14 pfam13428
Tetratricopeptide repeat;
359-399 4.12e-03

Tetratricopeptide repeat;


Pssm-ID: 463874 [Multi-domain]  Cd Length: 44  Bit Score: 35.09  E-value: 4.12e-03
                          10        20        30        40
                  ....*....|....*....|....*....|....*....|.
gi 719982495  359 ELLALSIQLLTKGDKDRAIALLRMALEKDPEYIRALVVLGQ 399
Cdd:pfam13428   3 ALLALARALLALGDPDEALALLERALALDPDDPEAWLALAQ 43
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
357-522 4.86e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 38.74  E-value: 4.86e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 357 PYELLALSIQLLTKGDKDRAIALlrmalekdPEYIRALVVLGQTLMQKGLLLEAIEHFEHAISkllivghpTDDENIDLL 436
Cdd:COG4785   47 ALAAAALAAAALAAERIDRALAL--------PDLAQLYYERGVAYDSLGDYDLAIADFDQALE--------LDPDLAEAY 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 437 ILssswAGVTYIRQGRNEEGIEHLERIAKLKePEDPKckAHYFDGLLLLASallneGRKSEAEKLLQMAAAYNP-----A 511
Cdd:COG4785  111 NN----RGLAYLLLGDYDAALEDFDRALELD-PDYAY--AYLNRGIALYYL-----GRYELAIADLEKALELDPndperA 178

                        170
                 ....*....|.
gi 719982495 512 YNEYLQQCRED 522
Cdd:COG4785  179 LWLYLAERKLD 189
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 356-467 5.27e-03

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 39.12  E-value: 5.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 719982495 356 SPYELLALSIQLLTKGDKDRAIALLRMALEK--DPEYIRALVVLgqtlmQKGLLLEAIEHFEHAISKllivgHPtddENI 433
Cdd:COG3071  192 DPELAAAYARALIALGDHDEAERLLREALKRqwDPRLVRLYGRL-----QGGDPAKQLKRAEKWLKK-----HP---NDP 258

                         90       100       110
                 ....*....|....*....|....*....|....
gi 719982495 434 DLLILssswAGVTYIRQGRNEEGIEHLERIAKLK 467
Cdd:COG3071  259 DLLLA----LGRLCLRNQLWGKAREYLEAALALR 288
TPR_12 pfam13424
Tetratricopeptide repeat;
358-418 6.07e-03

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 35.83  E-value: 6.07e-03
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 719982495  358 YELLALSIQLLtkGDKDRAIALLRMALE--------KDPEYIRALVVLGQTLMQKGLLLEAIEHFEHAI 418
Cdd:pfam13424   6 LNNLAAVLRRL--GRYDEALELLEKALEiarrllgpDHPLTATTLLNLGRLYLELGRYEEALELLERAL 72
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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