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Conserved domains on  [gi|71842398|gb|AAZ43288|]
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polymerase, partial [Lyssavirus rabies]

Protein Classification

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Mononeg_RNA_pol super family cl15638
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
 1-138 8.19e-60

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


The actual alignment was detected with superfamily member pfam00946:

Pssm-ID: 395756  Cd Length: 1042  Bit Score: 198.33  E-value: 8.19e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71842398      1 SWNLRLYFVITEKLLANYILPLFDALTMTDNLNKVFKKLIDRVTGQGL-----LDYSRVTYAFHLDYEKWNNHQRLESTE 75
Cdd:pfam00946  513 TYKLRLYQVLAEALLADGIGKLFPENTMVDDELDLKKKLLTLSSGSGQktrhhDSYERVTAFFTTDLEKYNLNWRYESTA 592

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71842398     76 DVFSVLDQVFGLKRVFSRTHEFFQKSWIYYSDRSDLIGLWEDqIYCLDMSNGPTCWNGQDGGL 138
Cdd:pfam00946  593 PFFSVLDELYGLPNLFNWTHERFEKSTIYVGDRSDPPDDRTH-INLDDVPEGDIFIHGPMGGI 654
 
Name Accession Description Interval E-value
Mononeg_RNA_pol pfam00946
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
 1-138 8.19e-60

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


Pssm-ID: 395756  Cd Length: 1042  Bit Score: 198.33  E-value: 8.19e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71842398      1 SWNLRLYFVITEKLLANYILPLFDALTMTDNLNKVFKKLIDRVTGQGL-----LDYSRVTYAFHLDYEKWNNHQRLESTE 75
Cdd:pfam00946  513 TYKLRLYQVLAEALLADGIGKLFPENTMVDDELDLKKKLLTLSSGSGQktrhhDSYERVTAFFTTDLEKYNLNWRYESTA 592

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71842398     76 DVFSVLDQVFGLKRVFSRTHEFFQKSWIYYSDRSDLIGLWEDqIYCLDMSNGPTCWNGQDGGL 138
Cdd:pfam00946  593 PFFSVLDELYGLPNLFNWTHERFEKSTIYVGDRSDPPDDRTH-INLDDVPEGDIFIHGPMGGI 654
 
Name Accession Description Interval E-value
Mononeg_RNA_pol pfam00946
Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the ...
 1-138 8.19e-60

Mononegavirales RNA dependent RNA polymerase; Members of the Mononegavirales including the Paramyxoviridae, like other non-segmented negative strand RNA viruses, have an RNA-dependent RNA polymerase composed of two subunits, a large protein L and a phosphoprotein P. This is a protein family of the L protein. The L protein confers the RNA polymerase activity on the complex. The P protein acts as a transcription factor.


Pssm-ID: 395756  Cd Length: 1042  Bit Score: 198.33  E-value: 8.19e-60
                           10        20        30        40        50        60        70        80
                   ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71842398      1 SWNLRLYFVITEKLLANYILPLFDALTMTDNLNKVFKKLIDRVTGQGL-----LDYSRVTYAFHLDYEKWNNHQRLESTE 75
Cdd:pfam00946  513 TYKLRLYQVLAEALLADGIGKLFPENTMVDDELDLKKKLLTLSSGSGQktrhhDSYERVTAFFTTDLEKYNLNWRYESTA 592

                           90       100       110       120       130       140
                   ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 71842398     76 DVFSVLDQVFGLKRVFSRTHEFFQKSWIYYSDRSDLIGLWEDqIYCLDMSNGPTCWNGQDGGL 138
Cdd:pfam00946  593 PFFSVLDELYGLPNLFNWTHERFEKSTIYVGDRSDPPDDRTH-INLDDVPEGDIFIHGPMGGI 654
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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