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Conserved domains on  [gi|71746894|ref|XP_822502|]
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glucose-6-phosphate 1-dehydrogenase [Trypanosoma brucei brucei TREU927]

Protein Classification

PTZ00309 family protein( domain architecture ID 11488367)

PTZ00309 family protein

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 1-556 0e+00

glucose-6-phosphate 1-dehydrogenase; Provisional


:

Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 986.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    1 MDGDLSQLGFLQEVDRFFDVLREKTLRDRPDNipeyvmqncrkvadtlRKDSCDIIPDAAAPELKERALTIVVLGASGDL 80
Cdd:PTZ00309   3 ESGRASQSAYVAEVDLITDVLRAQTLVDKPDN----------------GTESCDRIPCKVKDEDKSRALTIIVLGASGDL 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   81 ARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVEQWKKESLAKHFPRTKDRCPHIEAFLKTITYISGSYDGAEDFFRL 160
Cdd:PTZ00309  67 AKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVERWKKETLARFFKRLDDRECHLEQFLKHISYISGSYDEDEDFKRL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  161 NDVITKFEESFPGKQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlgWVRIIIEKPFGHDTESSNELSRQLEPLFEES 240
Cdd:PTZ00309 147 NKLIERMEEAFQGPEKGGNRLFYLALPPSVFASVCEGIHRGCMSKNG--WVRVIVEKPFGRDLESSEELSNQLEPLFDES 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  241 QIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQNHLTQILSLLAME 320
Cdd:PTZ00309 225 QLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGIIRDVMQNHLLQILALLAME 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  321 KPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTRSEDGSIPGYLEDPTVPRGSKCATFVVLRLFINNDRWDGVPFIIE 400
Cdd:PTZ00309 305 KPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASADGSIPGYLEDEGVPKDSTTPTFAAAVLHINNDRWEGVPFILE 384

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  401 AGKAVERRYLGIRIQFK--DEIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTELDLSYEHRYNITLPDAY 478
Cdd:PTZ00309 385 AGKALEERYVEIRIQFKgvDEFRPSGDDTQRNELVIRAQPSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYNVRLPDAY 464

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71746894  479 ESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKFVDDTGFKPLTGDIYQQRKLH 556
Cdd:PTZ00309 465 ERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQIDRGEVKPEPYPFGSRGPKEADELIKKNGFKSSKGYQWLQSNDQ 542
 
Name Accession Description Interval E-value
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 1-556 0e+00

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 986.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    1 MDGDLSQLGFLQEVDRFFDVLREKTLRDRPDNipeyvmqncrkvadtlRKDSCDIIPDAAAPELKERALTIVVLGASGDL 80
Cdd:PTZ00309   3 ESGRASQSAYVAEVDLITDVLRAQTLVDKPDN----------------GTESCDRIPCKVKDEDKSRALTIIVLGASGDL 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   81 ARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVEQWKKESLAKHFPRTKDRCPHIEAFLKTITYISGSYDGAEDFFRL 160
Cdd:PTZ00309  67 AKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVERWKKETLARFFKRLDDRECHLEQFLKHISYISGSYDEDEDFKRL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  161 NDVITKFEESFPGKQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlgWVRIIIEKPFGHDTESSNELSRQLEPLFEES 240
Cdd:PTZ00309 147 NKLIERMEEAFQGPEKGGNRLFYLALPPSVFASVCEGIHRGCMSKNG--WVRVIVEKPFGRDLESSEELSNQLEPLFDES 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  241 QIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQNHLTQILSLLAME 320
Cdd:PTZ00309 225 QLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGIIRDVMQNHLLQILALLAME 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  321 KPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTRSEDGSIPGYLEDPTVPRGSKCATFVVLRLFINNDRWDGVPFIIE 400
Cdd:PTZ00309 305 KPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASADGSIPGYLEDEGVPKDSTTPTFAAAVLHINNDRWEGVPFILE 384

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  401 AGKAVERRYLGIRIQFK--DEIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTELDLSYEHRYNITLPDAY 478
Cdd:PTZ00309 385 AGKALEERYVEIRIQFKgvDEFRPSGDDTQRNELVIRAQPSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYNVRLPDAY 464

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71746894  479 ESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKFVDDTGFKPLTGDIYQQRKLH 556
Cdd:PTZ00309 465 ERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQIDRGEVKPEPYPFGSRGPKEADELIKKNGFKSSKGYQWLQSNDQ 542
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 71-543 0e+00

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 598.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    71 IVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVE--QWKKESLAKHFPRTKDRcpHIEAFLKTITYIS 148
Cdd:TIGR00871   5 LVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEfrKVVREAIIKFETDEIDE--QWDEFAQRLSYVS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   149 GSYDGAEDFFRLNDVITKFEESFpgkQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESSNE 228
Cdd:TIGR00871  83 GDVDDDESYDSLAELLEQLDKTY---GTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQG-KWSRVVVEKPFGHDLASAQE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   229 LSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQN 308
Cdd:TIGR00871 159 LNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGALRDMVQN 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   309 HLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPAD--CVLGQYTRSEDG--SIPGYLEDPTVPRGSKCATFVVLR 384
Cdd:TIGR00871 239 HLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDnnTVRGQYGAGEIGgvSVPGYLEEEGVDKDSNTETFAALK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   385 LFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKDEirPFGV-------AAQRNELIIRAQPSEAMYLRLTAKTPGVLSDT 457
Cdd:TIGR00871 319 LEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDV--PSLLfkanerdANPRNALVIRIQPDEGVYLKFNAKKPGLNFET 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   458 HQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYP-YSAGSKGPAEAQKF 536
Cdd:TIGR00871 397 RPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPSPPnYPAGSWGPKEADEL 476


                  ....*..
gi 71746894   537 VDDTGFK 543
Cdd:TIGR00871 477 IRKDGRS 483
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 70-543 0e+00

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 544.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  70 TIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDvEQWK---KESLAKHFPRTKDRcPHIEAFLKTITY 146
Cdd:COG0364  11 DLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSD-EEFReevREALEEFSRKPFDE-EVWERFLERLHY 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 147 ISGSYDGAEDFFRLNDVITKFEESFPGkqkgGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESS 226
Cdd:COG0364  89 VSGDFTDPEGYERLKELLEELDEERTP----GNRVFYLATPPSLFGPICENLGAAGLATEG-GWRRVVIEKPFGHDLASA 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 227 NELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVV 306
Cdd:COG0364 164 RELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGALRDMV 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 307 QNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPAD----CVLGQYTRSE--DGSIPGYLEDPTVPRGSKCATF 380
Cdd:COG0364 244 QNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDvaenTVRGQYTAGWigGEPVPGYREEPGVAPDSTTETF 323

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 381 VVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKD-EIRPFGVAAQR---NELIIRAQPSEAMYLRLTAKTPGVLSD 456
Cdd:COG0364 324 VALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPvPHSLFRETAEElppNRLVIRIQPDEGISLRFNAKVPGLGMR 403

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 457 THQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKF 536
Cdd:COG0364 404 LRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEAADAL 483


                ....*..
gi 71746894 537 VDDTGFK 543
Cdd:COG0364 484 LARDGRS 490
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
259-543 1.85e-146

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 423.39  E-value: 1.85e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   259 VTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVL 338
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKVL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   339 RHVNPVTPAD----CVLGQYTRSEDG--SIPGYLEDPTVPRGSKCATFVVLRLFINNDRWDGVPFIIEAGKAVERRYLGI 412
Cdd:pfam02781  82 RSLRPITPEDvednVVRGQYGAGWIGgePVPGYREEEGVPPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   413 RIQFKD---EIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTELDLSYEHRYNITLPDAYESLIHEALLGR 489
Cdd:pfam02781 162 RIQFKDvphNLFRDPGTLPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERIPEAYERLLLDVMRGD 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 71746894   490 STNFVRKDELDAAWRIYTPLLEAIERGEttTYPYSAGSKGPAEAQKFVDDTGFK 543
Cdd:pfam02781 242 QTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRK 293
 
Name Accession Description Interval E-value
PTZ00309 PTZ00309
glucose-6-phosphate 1-dehydrogenase; Provisional
 1-556 0e+00

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 240353 [Multi-domain]  Cd Length: 542  Bit Score: 986.17  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    1 MDGDLSQLGFLQEVDRFFDVLREKTLRDRPDNipeyvmqncrkvadtlRKDSCDIIPDAAAPELKERALTIVVLGASGDL 80
Cdd:PTZ00309   3 ESGRASQSAYVAEVDLITDVLRAQTLVDKPDN----------------GTESCDRIPCKVKDEDKSRALTIIVLGASGDL 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   81 ARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVEQWKKESLAKHFPRTKDRCPHIEAFLKTITYISGSYDGAEDFFRL 160
Cdd:PTZ00309  67 AKKKTFPALFQLYCEGLLPSEVNIVGYARSKMSDVERWKKETLARFFKRLDDRECHLEQFLKHISYISGSYDEDEDFKRL 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  161 NDVITKFEESFPGKQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlgWVRIIIEKPFGHDTESSNELSRQLEPLFEES 240
Cdd:PTZ00309 147 NKLIERMEEAFQGPEKGGNRLFYLALPPSVFASVCEGIHRGCMSKNG--WVRVIVEKPFGRDLESSEELSNQLEPLFDES 224

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  241 QIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQNHLTQILSLLAME 320
Cdd:PTZ00309 225 QLYRIDHYLGKEMVQNLIVLRFANRVFEPLWNRNNIACVQITFKEDIGTEGRGGYFDSYGIIRDVMQNHLLQILALLAME 304

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  321 KPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTRSEDGSIPGYLEDPTVPRGSKCATFVVLRLFINNDRWDGVPFIIE 400
Cdd:PTZ00309 305 KPVSLSAEDIRDEKVKVLKCIEPIKMEECVLGQYTASADGSIPGYLEDEGVPKDSTTPTFAAAVLHINNDRWEGVPFILE 384

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  401 AGKAVERRYLGIRIQFK--DEIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTELDLSYEHRYNITLPDAY 478
Cdd:PTZ00309 385 AGKALEERYVEIRIQFKgvDEFRPSGDDTQRNELVIRAQPSEAMYLKITAKVPGLSNDLHQTELDLTYKTRYNVRLPDAY 464

                        490       500       510       520       530       540       550
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 71746894  479 ESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKFVDDTGFKPLTGDIYQQRKLH 556
Cdd:PTZ00309 465 ERLILDALLGDSTNFVRKDELDVAWRIFTPLLHQIDRGEVKPEPYPFGSRGPKEADELIKKNGFKSSKGYQWLQSNDQ 542
zwf TIGR00871
glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and ...
 71-543 0e+00

glucose-6-phosphate 1-dehydrogenase; This enzyme (EC 1.1.1.49) acts on glucose 6-phospate and reduces NADP(+). An alternate name appearing in the literature for the human enzyme, based on a slower activity with beta-D-glucose, is glucose 1-dehydrogenase (EC 1.1.1.47), but that name more properly describes a subfamily of the short chain dehydrogenases/reductases family. This is a well-studied enzyme family, with sequences available from well over 50 species. The trusted cutoff is set above the score for the Drosophila melanogaster CG7140 gene product, a homolog of unknown function. G6PD homologs from the bacteria Aquifex aeolicus and Helicobacter pylori lack several motifs well conserved most other members, were omitted from the seed alignment, and score well below the trusted cutoff. [Energy metabolism, Pentose phosphate pathway]


Pssm-ID: 273312 [Multi-domain]  Cd Length: 487  Bit Score: 598.15  E-value: 0e+00
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    71 IVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVE--QWKKESLAKHFPRTKDRcpHIEAFLKTITYIS 148
Cdd:TIGR00871   5 LVIFGASGDLARKKLFPALYRLFRNGLLPPDFRIVGVARRDWSVEEfrKVVREAIIKFETDEIDE--QWDEFAQRLSYVS 82

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   149 GSYDGAEDFFRLNDVITKFEESFpgkQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESSNE 228
Cdd:TIGR00871  83 GDVDDDESYDSLAELLEQLDKTY---GTEGNRLFYLATPPSLFGTIIKQLKKHGLNEQG-KWSRVVVEKPFGHDLASAQE 158

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   229 LSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQN 308
Cdd:TIGR00871 159 LNKALRAVFKEDQIYRIDHYLGKETVQNLLVLRFANQIFEPLWNRRYIDHVQITVAESFGVEGRGGYYDKSGALRDMVQN 238

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   309 HLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPAD--CVLGQYTRSEDG--SIPGYLEDPTVPRGSKCATFVVLR 384
Cdd:TIGR00871 239 HLLQLLALVAMEPPVSFDADSIRDEKVKVLKALRPIDPDDnnTVRGQYGAGEIGgvSVPGYLEEEGVDKDSNTETFAALK 318

                         330       340       350       360       370       380       390       400
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   385 LFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKDEirPFGV-------AAQRNELIIRAQPSEAMYLRLTAKTPGVLSDT 457
Cdd:TIGR00871 319 LEIDNWRWAGVPFYLRTGKRLPEKVTEIRIQFRDV--PSLLfkanerdANPRNALVIRIQPDEGVYLKFNAKKPGLNFET 396

                         410       420       430       440       450       460       470       480
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   458 HQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYP-YSAGSKGPAEAQKF 536
Cdd:TIGR00871 397 RPVKLDFSYASRFGELLPEAYERLLLDALLGDHTLFARDDEVEEAWRIVTPILEAWAANKGPSPPnYPAGSWGPKEADEL 476


                  ....*..
gi 71746894   537 VDDTGFK 543
Cdd:TIGR00871 477 IRKDGRS 483
PLN02539 PLN02539
glucose-6-phosphate 1-dehydrogenase
 69-542 0e+00

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 178154 [Multi-domain]  Cd Length: 491  Bit Score: 592.08  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   69 LTIVVLGASGDLARNKTFPALFQLFCNG-LIPRTINIVGYARTKMPDVEQwkKESLAKHFPRTK-DRCPHIEAFLKTITY 146
Cdd:PLN02539  18 LSIIVLGASGDLAKKKTFPALFNLYRQGfLPPDEVHIFGYARSKITDEEL--RDRIRGYLKDEKnAPAEAVSKFLQLIKY 95

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  147 ISGSYDGAEDFFRLNDVITKFEESFPGKQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGLgWVRIIIEKPFGHDTESS 226
Cdd:PLN02539  96 VSGAYDSEEGFRRLDKEISEHEISKNSAEGSSRRLFYLALPPSVYPPVCKMIKKCCMNKSGL-WTRIVVEKPFGKDLESA 174

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  227 NELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVV 306
Cdd:PLN02539 175 EELSSQIGELFDESQLYRIDHYLGKELVQNLLVLRFANRFFLPLWNRDNIANVQIVFREDFGTEGRGGYFDEYGIIRDII 254

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  307 QNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYtrsedgsiPGYLEDPTVPRGSKCATFVVLRLF 386
Cdd:PLN02539 255 QNHLLQVLCLVAMEKPVSLKPEHIRDEKVKVLQSVEPIKDEEVVLGQY--------EGYRDDPTVPDDSNTPTFASVVLR 326

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  387 INNDRWDGVPFIIEAGKAVERRYLGIRIQFKD---EIrpFGVAAQ-RNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTEL 462
Cdd:PLN02539 327 INNERWEGVPFILKAGKALDSRKAEIRVQFKDvpgDI--FKCQKQgRNEFVIRLQPSEAMYMKLTVKQPGLEMSTVQSEL 404

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  463 DLSYEHRY-NITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKFVDDTG 541
Cdd:PLN02539 405 DLSYGQRYqDVVIPEAYERLILDTIRGDQQHFVRRDELKAAWEIFTPLLHRIDAGKVKPIPYKQGSRGPAEADELLEKAG 484


                 .
gi 71746894  542 F 542
Cdd:PLN02539 485 Y 485
Zwf COG0364
Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; ...
 70-543 0e+00

Glucose-6-phosphate 1-dehydrogenase [Carbohydrate transport and metabolism]; Glucose-6-phosphate 1-dehydrogenase is part of the Pathway/BioSystem: Pentose phosphate pathway


Pssm-ID: 440133 [Multi-domain]  Cd Length: 495  Bit Score: 544.67  E-value: 0e+00
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  70 TIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDvEQWK---KESLAKHFPRTKDRcPHIEAFLKTITY 146
Cdd:COG0364  11 DLVIFGATGDLARRKLLPALYNLYRDGLLPEGFRIIGVARRDWSD-EEFReevREALEEFSRKPFDE-EVWERFLERLHY 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 147 ISGSYDGAEDFFRLNDVITKFEESFPGkqkgGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESS 226
Cdd:COG0364  89 VSGDFTDPEGYERLKELLEELDEERTP----GNRVFYLATPPSLFGPICENLGAAGLATEG-GWRRVVIEKPFGHDLASA 163

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 227 NELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVV 306
Cdd:COG0364 164 RELNDELGRVFDESQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDGAGALRDMV 243

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 307 QNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPAD----CVLGQYTRSE--DGSIPGYLEDPTVPRGSKCATF 380
Cdd:COG0364 244 QNHLLQLLCLVAMEPPASLDADAIRDEKVKVLRALRPITPEDvaenTVRGQYTAGWigGEPVPGYREEPGVAPDSTTETF 323

                       330       340       350       360       370       380       390       400
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 381 VVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKD-EIRPFGVAAQR---NELIIRAQPSEAMYLRLTAKTPGVLSD 456
Cdd:COG0364 324 VALKLEIDNWRWAGVPFYLRTGKRLPERVTEIVIQFKPvPHSLFRETAEElppNRLVIRIQPDEGISLRFNAKVPGLGMR 403

                       410       420       430       440       450       460       470       480
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894 457 THQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKF 536
Cdd:COG0364 404 LRPVSLDFSYSDAFGERSPEAYERLLLDVMRGDQTLFMRRDEVEAAWRWVDPILEAWAEEPEPPPPYPAGSWGPEAADAL 483


                ....*..
gi 71746894 537 VDDTGFK 543
Cdd:COG0364 484 LARDGRS 490
PRK05722 PRK05722
glucose-6-phosphate 1-dehydrogenase; Validated
 70-543 0e+00

glucose-6-phosphate 1-dehydrogenase; Validated


Pssm-ID: 235579 [Multi-domain]  Cd Length: 495  Bit Score: 542.80  E-value: 0e+00
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   70 TIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDvEQWK---KESLAKHFPRTKDRcPHIEAFLKTITY 146
Cdd:PRK05722  11 DLVIFGATGDLARRKLLPALYNLYKAGLLPEDFRIIGVARRDWSD-EDFRevvREALKEFARTPFDE-EVWERFLSRLYY 88

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  147 ISGSYDGAEDFFRLNDVITKFEESfpgKQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESS 226
Cdd:PRK05722  89 VSGDVTDPESYERLKELLEELDEE---RGTGGNRVFYLATPPSLFGTICENLAAAGLNEGG-GWRRVVIEKPFGHDLASA 164

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  227 NELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVV 306
Cdd:PRK05722 165 RELNDQVGEVFKEEQIYRIDHYLGKETVQNLLALRFANALFEPLWNRNYIDHVQITVAETVGVEGRGGYYDKSGALRDMV 244

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  307 QNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPAD----CVLGQYTRSE--DGSIPGYLEDPTVPRGSKCATF 380
Cdd:PRK05722 245 QNHLLQLLALVAMEPPASLDADSIRDEKVKVLRALRPITPEDvkenTVRGQYTAGWigGKPVPGYREEEGVNPDSTTETF 324

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  381 VVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKD-EIRPFGVAAQR---NELIIRAQPSEAMYLRLTAKTPGVLSD 456
Cdd:PRK05722 325 VALKLEIDNWRWAGVPFYLRTGKRLPKKVTEIVIVFKPpPHNLFEESAEElgpNKLVIRIQPDEGISLRFNAKVPGEGME 404

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  457 THQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQKF 536
Cdd:PRK05722 405 LRPVKLDFSYSEAFGEASPEAYERLLLDVMLGDQTLFVRRDEVEAAWKWVDPILEAWEADGGPPPPYPAGTWGPEAADAL 484


                 ....*..
gi 71746894  537 VDDTGFK 543
Cdd:PRK05722 485 LARDGRS 491
PRK12853 PRK12853
glucose-6-phosphate dehydrogenase;
67-541 1.25e-165

glucose-6-phosphate dehydrogenase;


Pssm-ID: 237233 [Multi-domain]  Cd Length: 482  Bit Score: 479.40  E-value: 1.25e-165
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   67 RALTIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDvEQWK---KESLAKHFpRTKDRCPHIEAFLKT 143
Cdd:PRK12853   7 PPCTLVIFGATGDLARRKLLPALYRLARAGLLPEDLRIIGVGRDDWSD-EQWRarvRESLRAFG-ADGFDDAVWDRLAAR 84

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  144 ITYISGSYDGAEDFFRLNDVItkfeesfpgkQKGGNRLFYLALPPSVFMHACTGIRTHvmqkpGL--GWVRIIIEKPFGH 221
Cdd:PRK12853  85 LSYVQGDVTDPADYARLAEAL----------GPGGNPVFYLAVPPSLFAPVVENLGAA-----GLlpEGRRVVLEKPFGH 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  222 DTESSNELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGI 301
Cdd:PRK12853 150 DLASARALNATLAKVFDEDQIYRIDHFLGKETVQNLLALRFANALLEPLWNRNHIDHVQITVAETLGVEGRGGFYDATGA 229

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  302 IRDVVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPADC--VLGQYTRSEDG--SIPGYLEDPTVPRGSKC 377
Cdd:PRK12853 230 LRDMVQNHLLQLLALVAMEPPASFDADAVRDEKAKVLRAIRPLDPDDVhtVRGQYTAGTVGgePVPGYREEPGVDPDSRT 309

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  378 ATFVVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKD---EIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVL 454
Cdd:PRK12853 310 ETFVALKLEIDNWRWAGVPFYLRTGKRLAERRTEIVITFKPvphALFRGTGVEPPNRLVIRLQPDEGISLELNVKRPGPG 389

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  455 SDTHQTELDLSYEHRynITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPAEAQ 534
Cdd:PRK12853 390 MRLRPVELDADYADD--ERPLEAYERLLLDVLRGDPTLFVRADEVEAAWRIVDPVLDAWAADPVPPHEYPAGSWGPAAAD 467


                 ....*..
gi 71746894  535 KFVDDTG 541
Cdd:PRK12853 468 ALLARDG 474
PLN02640 PLN02640
glucose-6-phosphate 1-dehydrogenase
 63-534 3.62e-161

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215344 [Multi-domain]  Cd Length: 573  Bit Score: 471.42  E-value: 3.62e-161
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   63 ELKERALTIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVE--QWKKESLAKHFPRTKDRCPHIEAF 140
Cdd:PLN02640  83 EKGESTLSITVVGASGDLAKKKIFPALFALFYEDWLPENFTVFGYARTKLTDEElrDMISSTLTCRIDQRENCGDKMDQF 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  141 LKTITYISGSYDGAEDFFRLNdviTKFEESFPGKQKggNRLFYLALPPSVFMHA--CTGIRTHVMQkpglGWVRIIIEKP 218
Cdd:PLN02640 163 LKRCFYHSGQYDSEEDFAELN---KKLKEKEAGKLS--NRLFYLSIPPNIFVDVvrCASLRASSEN----GWTRVIVEKP 233

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  219 FGHDTESSNELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDK 298
Cdd:PLN02640 234 FGRDSESSGELTRCLKQYLTEEQIFRIDHYLGKELVENLSVLRFSNLVFEPLWSRNYIRNVQLIFSEDFGTEGRGGYFDN 313

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  299 AGIIRDVVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTRSEDG--SIPGYLEDPTVPRGSK 376
Cdd:PLN02640 314 YGIIRDIMQNHLLQILALFAMETPVSLDAEDIRNEKVKVLRSMKPLQLEDVIVGQYKGHSKGgkSYPAYTDDPTVPKHSL 393

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  377 CATFVVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKD-----EIRPFGVAAQR--NELIIRAQPSEAMYLRLTAK 449
Cdd:PLN02640 394 TPTFAAAALFINNARWDGVPFLMKAGKALHTRRAEIRVQFRHvpgnlYKRNFGTDLDKatNELVLRVQPDEAIYLKINNK 473

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  450 TPGVLSDTHQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKG 529
Cdd:PLN02640 474 VPGLGMRLDRSDLNLLYRARYPREIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPELYPYGSRG 553


                 ....*
gi 71746894  530 PAEAQ 534
Cdd:PLN02640 554 PVGAH 558
PLN02333 PLN02333
glucose-6-phosphate 1-dehydrogenase
 65-534 5.41e-158

glucose-6-phosphate 1-dehydrogenase


Pssm-ID: 215191 [Multi-domain]  Cd Length: 604  Bit Score: 464.45  E-value: 5.41e-158
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   65 KERALTIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDVE--QWKKESLAKHFPRTKDRCPHIEAFLK 142
Cdd:PLN02333 114 DESTVSITVVGASGDLAKKKIFPALFALYYEGCLPEHFTIFGYARSKMTDAElrNMVSKTLTCRIDKRENCGEKMEEFLK 193

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  143 TITYISGSYDGAEDFFRLNDvitKFEESFPGKQKggNRLFYLALPPSVFMHA--CTGIRThvmqKPGLGWVRIIIEKPFG 220
Cdd:PLN02333 194 RCFYHSGQYDSQEHFAELDK---KLKEHEGGRVS--NRLFYLSIPPNIFVDAvkCASSSA----SSVNGWTRVIVEKPFG 264

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  221 HDTESSNELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAG 300
Cdd:PLN02333 265 RDSESSAALTKSLKQYLEEDQIFRIDHYLGKELVENLSVLRFSNLIFEPLWSRQYIRNVQFIFSEDFGTEGRGGYFDNYG 344

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  301 IIRDVVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTRSEDGSI--PGYLEDPTVPRGSKCA 378
Cdd:PLN02333 345 IIRDIMQNHLLQILALFAMETPVSLDAEDIRNEKVKVLRSMRPIQLEDVVIGQYKSHTKGGVtyPAYTDDKTVPKGSLTP 424

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  379 TFVVLRLFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKDEI-----RPFGVAAQR--NELIIRAQPSEAMYLRLTAKTP 451
Cdd:PLN02333 425 TFAAAALFIDNARWDGVPFLMKAGKALHTKSAEIRVQFRHVPgnlynRNFGTDLDQatNELVIRVQPDEAIYLKINNKVP 504

                        410       420       430       440       450       460       470       480
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  452 GVLSDTHQTELDLSYEHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEAIERGETTTYPYSAGSKGPA 531
Cdd:PLN02333 505 GLGMRLDRSNLNLLYAARYSKEIPDAYERLLLDAIEGERRLFIRSDELDAAWALFTPLLKELEEKKIIPEYYPYGSRGPV 584


                 ...
gi 71746894  532 EAQ 534
Cdd:PLN02333 585 GAH 587
G6PD_C pfam02781
Glucose-6-phosphate dehydrogenase, C-terminal domain;
259-543 1.85e-146

Glucose-6-phosphate dehydrogenase, C-terminal domain;


Pssm-ID: 460694  Cd Length: 295  Bit Score: 423.39  E-value: 1.85e-146
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   259 VTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRDVVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVL 338
Cdd:pfam02781   2 VLRFANAIFEPLWNRNYIDHVQITVAETLGVEGRGGYYDQAGALRDMVQNHLLQLLALVAMEPPVSFDAEDIRDEKVKVL 81

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   339 RHVNPVTPAD----CVLGQYTRSEDG--SIPGYLEDPTVPRGSKCATFVVLRLFINNDRWDGVPFIIEAGKAVERRYLGI 412
Cdd:pfam02781  82 RSLRPITPEDvednVVRGQYGAGWIGgePVPGYREEEGVPPDSRTETFAALKLFIDNWRWAGVPFYLRTGKRLPERVTEI 161

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   413 RIQFKD---EIRPFGVAAQRNELIIRAQPSEAMYLRLTAKTPGVLSDTHQTELDLSYEHRYNITLPDAYESLIHEALLGR 489
Cdd:pfam02781 162 RIQFKDvphNLFRDPGTLPPNELVIRIQPDEGIYLKFNAKVPGLGMRLRPVELDFSYSDRFGERIPEAYERLLLDVMRGD 241

                         250       260       270       280       290
                  ....*....|....*....|....*....|....*....|....*....|....
gi 71746894   490 STNFVRKDELDAAWRIYTPLLEAIERGEttTYPYSAGSKGPAEAQKFVDDTGFK 543
Cdd:pfam02781 242 QTLFVRSDEVEAAWRIVDPILEAWDEEK--PPPYPAGSWGPKAADELLARDGRK 293
PRK12854 PRK12854
glucose-6-phosphate 1-dehydrogenase; Provisional
 70-533 3.01e-115

glucose-6-phosphate 1-dehydrogenase; Provisional


Pssm-ID: 237234 [Multi-domain]  Cd Length: 484  Bit Score: 350.49  E-value: 3.01e-115
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   70 TIVVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMPDvEQWK---KESLAKHFPRTKDRCPhIEAFLKTITY 146
Cdd:PRK12854  13 VFVLFGATGDLAKRKLLPGLFHLARAGLLPPDWRIVGTGRGDVSA-EAFRehaRDALDEFGARKLDDGE-WARFAKRLRY 90

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  147 ISGSY--DGAEDffrLNDVITKFEESFPGkqkGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlgwvRIIIEKPFGHDTE 224
Cdd:PRK12854  91 VPGGFlsAGPGA---LAAAVAAARAELGG---DARLVHYLAVPPSAFLDVTRALGEAGLAEGS----RVVMEKPFGTDLA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  225 SSNELSRQLEPLFEESQIFRIDHYLGKEMVQNIVVTRFANRVFSALWNNNNIACVRITFKESIGTEGRGGYFDKAGIIRD 304
Cdd:PRK12854 161 SAEALNAAVHEVFDESQIFRIDHFLGKEAAQNILAFRFANGLFEPIWNREFIDHVQIDVPETLGVDTRAAFYDATGAYRD 240

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  305 VVQNHLTQILSLLAMEKPRSLSPEDIRDEKVIVLRHVNPVTPADCVLGQYTrsedgsipGYLEDPTVPRGSKCATFVVLR 384
Cdd:PRK12854 241 MVVTHLFQVLAFVAMEPPTALEPDAISEEKNKVFRSMRPLDPAEVVRGQYS--------GYRDEPGVAPDSTTETFVALK 312

                        330       340       350       360       370       380       390       400
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894  385 LFINNDRWDGVPFIIEAGKAVERRYLGIRIQFKDEIRPF----GVAAQR-NELIIRAQPSEAMYLRLTAKTPGVLSDTHQ 459
Cdd:PRK12854 313 VWIDNWRWAGVPFYLRTGKRMAEGQRIISIAFREPPYSMfpagSVGAQGpDHLTFDLADNSKVSLSFYGKRPGPGMRLDK 392

                        410       420       430       440       450       460       470
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 71746894  460 TELDLSY-EHRYNITLPDAYESLIHEALLGRSTNFVRKDELDAAWRIYTPLLEaiERGEttTYPYSAGSKGPAEA 533
Cdd:PRK12854 393 LSLQFSLkDTGPKGDVLEAYERLILDALRGDHTLFTTADGIESLWEVSQPLLE--DPPP--VKPYAPGSWGPNAI 463
G6PD_N pfam00479
Glucose-6-phosphate dehydrogenase, NAD binding domain;
72-256 8.08e-81

Glucose-6-phosphate dehydrogenase, NAD binding domain;


Pssm-ID: 459827 [Multi-domain]  Cd Length: 178  Bit Score: 250.80  E-value: 8.08e-81
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894    72 VVLGASGDLARNKTFPALFQLFCNGLIPRTINIVGYARTKMpDVEQWK---KESLAKHFPRTKDrcpHIEAFLKTITYIS 148
Cdd:pfam00479   1 VIFGATGDLAKRKLFPALYNLYRDGLLPEGFRIIGVARRDL-SDEEFRervREALKEFKELDEE---KWDRFLERLHYVS 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 71746894   149 GSYDGAEDFFRLNDVITKFEEsfpgkQKGGNRLFYLALPPSVFMHACTGIRTHVMQKPGlGWVRIIIEKPFGHDTESSNE 228
Cdd:pfam00479  77 GDFDDPESYEKLKERLEEHED-----ETRGNRLFYLAVPPSLFGPIAENLGRAGLSEEG-GWRRVVIEKPFGHDLESARE 150

                         170       180
                  ....*....|....*....|....*...
gi 71746894   229 LSRQLEPLFEESQIFRIDHYLGKEMVQN 256
Cdd:pfam00479 151 LNDQLAKVFKEEQIYRIDHYLGKETVQN 178
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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