|
Name |
Accession |
Description |
Interval |
E-value |
| CobT |
COG2038 |
NaMN:DMB phosphoribosyltransferase [Coenzyme transport and metabolism]; NaMN:DMB ... |
863-1212 |
2.64e-160 |
|
NaMN:DMB phosphoribosyltransferase [Coenzyme transport and metabolism]; NaMN:DMB phosphoribosyltransferase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441641 Cd Length: 351 Bit Score: 481.12 E-value: 2.64e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 863 DLLAETVAQIRPLDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWP 942
Cdd:COG2038 2 SLLEETLPAIPPLDEEAMAAAQARLDNLTKPPGSLGRLEELAVQLAGIQGTLPPRLDRPA-VVVFAADHGVAAEGVSAYP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 943 QEVTAQMVANFLGGGAVCNAFATQVGAEVCVVDVGVATDLPATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETA 1022
Cdd:COG2038 81 QEVTAQMVRNFLAGGAAINVLARQAGADLRVVDVGVAADLPPLPGLIDRKVARGTGNFAKGPAMTREEAEAALEAGIEIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1023 RDLVAAGNKALLTGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIG 1102
Cdd:COG2038 161 DELIAAGADLLGTGEMGIGNTTPAAALLAALTGLPPEEVVGRGTGLDDEGLARKIAVIRRALARHRPDPADPLDVLAKVG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1103 GFEHAAMVGLLLGGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGT 1182
Cdd:COG2038 241 GFEIAAMAGAMLGAAARRVPVVVDGFISTAAALVAVRLAPGVRDYLIFSHRSAEPGHRLALEALGLEPLLDLGMRLGEGT 320
|
330 340 350
....*....|....*....|....*....|
gi 7106671 1183 GALLALPMVQSTARAMHEVATFDSAGVTEK 1212
Cdd:COG2038 321 GAALALPLLRAAVALLNEMATFEEAGVSGK 350
|
|
| DBI_PRT |
pfam02277 |
Phosphoribosyltransferase; This family of proteins represent the nicotinate-nucleotide- ... |
872-1206 |
7.07e-147 |
|
Phosphoribosyltransferase; This family of proteins represent the nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) enzymes involved in dimethylbenzimidazole synthesis. This function is essential to de novo cobalamin (vitamin B12) production in bacteria. Nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) from Salmonella enterica plays a central role in the synthesis of alpha-ribazole-5'-phosphate, an intermediate for the lower ligand of cobalamin.
Pssm-ID: 460520 Cd Length: 332 Bit Score: 445.29 E-value: 7.07e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 872 IRPLDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVA 951
Cdd:pfam02277 1 IPPPDEEAMAAARARLDQLTKPLGSLGRLEELAVQLAGIQGTLPPPLDKKA-VVVFAGDHGVAAEGVSAYPQEVTAQMVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 952 NFLGGGAVCNAFATQVGAEVCVVDVGVATDlpATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNK 1031
Cdd:pfam02277 80 NFLAGGAAINVLARQAGADLRVVDVGVDDD--DLPALINRKVRRGTGNFAKEPAMTREEAEAALEAGIELADELADAGAD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1032 ALLTGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVG 1111
Cdd:pfam02277 158 LLGTGEMGIGNTTPAAALLAALTGLPPEEVTGRGTGLDDEGLARKIAVIRQALARHRPDPADPLDVLAKVGGFEIAAMAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1112 LLLGGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMV 1191
Cdd:pfam02277 238 AILGAAARRIPVVLDGFISTAAALVAVRLAPGVRDYLIASHRSAEPGHRLALEALGLEPLLDLGMRLGEGTGAALALPLL 317
|
330
....*....|....*
gi 7106671 1192 QSTARAMHEVATFDS 1206
Cdd:pfam02277 318 DAALALLNEMATFEE 332
|
|
| cobT_DBIPRT |
TIGR03160 |
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Members of this family ... |
876-1209 |
1.85e-141 |
|
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Members of this family are nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, an enzyme of cobalamin biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 274459 Cd Length: 333 Bit Score: 431.20 E-value: 1.85e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 876 DAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFLG 955
Cdd:TIGR03160 1 DAEARAAAQARQDSLTKPPGSLGRLEELAVQLAGIQGTVPPRIDRPA-VVVFAGDHGVAAEGVSAFPQEVTAQMVENFLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 956 GGAVCNAFATQVGAEVCVVDVGVATDLPATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALLT 1035
Cdd:TIGR03160 80 GGAAINVLARQAGADLRVVDVGVDHDLPEHPGLINRKVRRGTANIAQGPAMTREEAEAALEAGIEAADEAIDSGADLLGT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1036 GEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLLG 1115
Cdd:TIGR03160 160 GEMGIGNTTPAAALLAALTGLPPEEVVGRGTGLDDEGLARKVAVIRRALERHRPNAGDPLDVLAKVGGFEIAAMAGAILG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1116 GASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQSTA 1195
Cdd:TIGR03160 240 AAARRIPVLVDGFISTAAALVAVRLAPGVRDYLIASHRSAEPGHRAVLEALGLEPLLDLGMRLGEGTGAALALPLVRAAA 319
|
330
....*....|....
gi 7106671 1196 RAMHEVATFDSAGV 1209
Cdd:TIGR03160 320 AILNEMATFAEAGV 333
|
|
| cobT |
PRK00105 |
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed |
875-1211 |
1.57e-136 |
|
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed
Pssm-ID: 234636 Cd Length: 335 Bit Score: 418.38 E-value: 1.57e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 875 LDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFL 954
Cdd:PRK00105 1 PDAAAMAAAQARIDQLTKPPGSLGRLEELAVQLAGIQGTEPPRVERPA-VVVFAGDHGVAEEGVSAYPQEVTAQMVANFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 955 GGGAVCNAFATQVGAEVCVVDVGVATDLPaTPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALL 1034
Cdd:PRK00105 80 AGGAAINVLARQAGADLEVVDLGVDAPEP-LPGLINMRVARGTGNIAKEPAMTREEAEAALAAGAALADEAADAGTDLLG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1035 TGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLL 1114
Cdd:PRK00105 159 VGEMGIGNTTPAAALVAALTGGDPEEVVGRGTGIDDAGLARKIAVVRRALARHRPALQDPLDVLAKVGGFEIAAMAGAIL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1115 GGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQST 1194
Cdd:PRK00105 239 GAAVRRIPVLLDGFISTAAALVAVRLAPGVRDYLIFSHRSAEPGHRLALEHLGLEPLLDLGMRLGEGTGAALALPLVRAA 318
|
330
....*....|....*..
gi 7106671 1195 ARAMHEVATFDSAGVTE 1211
Cdd:PRK00105 319 VAFYNEMATFAEAGVSD 335
|
|
| DMB-PRT_CobT |
cd02439 |
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called ... |
891-1207 |
3.46e-121 |
|
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT/CobT, not to be confused with the CobT subunit of cobaltochelatase, which does not belong to this group) catalyzes the synthesis of alpha-ribazole-5'-phosphate, from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). This function is essential to the anaerobic biosynthesis pathway of cobalamin (vitamin B12), which is the largest and most complex cofactor in a number of enzyme-catalyzed reactions in bacteria, archaea and eukaryotes. Only eubacteria and archaebacteria can synthesize vitamin B12; multicellular organisms have lost this ability during evolution. DMB-PRT/CobT works sequentially with CobC (a phosphatase) to couple the lower ligand of cobalamin to a ribosyl moiety. DMB is the most common lower ligand of cobamides; other lower ligands include adenine, 5-methoxybenzimidazole or phenol. It has been suggested that earlier metabolic or enzymatic steps may control which lower ligand is available to DMB-PRT/CobT. In Salmonella enterica, for example, the lower ligand is DMB under aerobic conditions and adenine or 2-methyladenine under anaerobic conditions. Salmonella enterica DMB-PRT/CobT is a homodimer with two active sites, each active site is comprised of residues from both monomers. This group includes two distinct subfamilies, one archaeal-like, the other comprised of bacterial sequences.
Pssm-ID: 143332 Cd Length: 315 Bit Score: 376.83 E-value: 3.46e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 891 TKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFLGGGAVCNAFATQVGAE 970
Cdd:cd02439 1 TKPLGSLGRLETLASQIAGIQGAGPPALPEKT-VLTFAADHGVAAEGVSAYPQEVTAQMVGNFPTGGAAINALARLAGAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 971 VCVVDVGVATDLPATPGLLpRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALLTGEMGIANTTASAALI 1050
Cdd:cd02439 80 LLVVDAGLAVDPPVPPILL-GKVRGGTANFAKGPAMTREEAEAALEAGIELAREALDSGYDLLVIGEMGIGNTTTAAAVL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1051 SVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLLGGASLRTPVILDGVSA 1130
Cdd:cd02439 159 AALGGDPAEEVSGRGTGLPDEGLERKIAVVEEALARNGPDPDDPLDVLAKVGGPEIAAMAGLILGAAARRVPVLLDGFIQ 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7106671 1131 GAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQSTARAMHEVATFDSA 1207
Cdd:cd02439 239 MAAALAAVRLAPDARDYLIATHRSVEPGHRLLLEALGLEPLLDLGMRLGEGTGAALALPLLRGAAAELNEMATFEEA 315
|
|
| BluB |
TIGR02476 |
5,6-dimethylbenzimidazole synthase; A previously published hypothesis that BluB, involved in ... |
642-847 |
1.62e-101 |
|
5,6-dimethylbenzimidazole synthase; A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 162875 Cd Length: 205 Bit Score: 319.77 E-value: 1.62e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 642 YDDAERAAVLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKS 721
Cdd:TIGR02476 1 FSDAERAAVYRLIRERRDVRH-FRSDPVPEAVLERLLDAAHHAPSVGFSQPWRFVRVESPATREAVHALFTRANQAAAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 722 LPKGRAKQFKELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREM 801
Cdd:TIGR02476 80 YDGERASQYHRLKLEGIREAPVQLAVFCDDARGEGHGLGRHTMPEMLRYSVACAIQNLWLAARAEGLGVGWVSILDPDAV 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 7106671 802 VRALGLPEHLDVVAYLCVGYVDEFPDEPELMQAGWSKRRPLSWVVH 847
Cdd:TIGR02476 160 RRLLGVPEGWRLVAYLCLGWPDAFYDEPELERAGWQERRPLEWRRY 205
|
|
| BluB |
cd02145 |
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5, ... |
652-847 |
1.39e-97 |
|
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.
Pssm-ID: 380321 Cd Length: 196 Bit Score: 308.90 E-value: 1.39e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 652 KVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKSLPKGRAKQFK 731
Cdd:cd02145 2 RVIRWRRDVRH-FRPDPVPEEVLERLLQAAHLAPSVGLMQPWRFVRVRSAATRKAVHELFQRANAEAAEMYTGERAAQYR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 732 ELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEHL 811
Cdd:cd02145 81 TLKLEGIEEAPLQLAVFCDRARAGGHGLGRTTMPEMDLYSSVCAVQNLWLAARAEGLGVGWVSILDPDEVKRLLGIPEHW 160
|
170 180 190
....*....|....*....|....*....|....*.
gi 7106671 812 DVVAYLCVGYVDEFPDEPELMQAGWSKRRPLSWVVH 847
Cdd:cd02145 161 EPVAYLCIGYPEFFYDEPELEQAGWEQRRPLEWVVF 196
|
|
| NfnB |
COG0778 |
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway ... |
650-846 |
1.69e-43 |
|
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 440541 [Multi-domain] Cd Length: 163 Bit Score: 155.40 E-value: 1.69e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELatrqrdayakslpkgrakq 729
Cdd:COG0778 1 LLELLLTRRSVRK-FTDKPVSDEELEELLEAARLAPSAGNLQPWRFVVVRDPELRERLAEA------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 FKELKIEAILDTPVNIVVTADPTRGGRhtlgrhTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPE 809
Cdd:COG0778 61 LAEANQEWVADAPVLIVVCADPDRSEK------VPERYALLDAGIAAQNLLLAARALGLGTCWIGGFDPEKVRELLGLPE 134
|
170 180 190
....*....|....*....|....*....|....*..
gi 7106671 810 HLDVVAYLCVGYVDEFPDEpelmqagwSKRRPLSWVV 846
Cdd:COG0778 135 GEEPVALLALGYPAEELNP--------RPRKPLEEVV 163
|
|
| Nitroreductase |
pfam00881 |
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent ... |
654-821 |
6.80e-36 |
|
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.
Pssm-ID: 425926 [Multi-domain] Cd Length: 168 Bit Score: 134.06 E-value: 6.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 654 MRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELA---TRQRDAYAKSLPKGRAKQF 730
Cdd:pfam00881 1 IRQRRSVRK-FDPEPVPKEVLEEILEAARRAPSAGNLQPWRFYVVTDGELRYRLAEAAlelLLVEPAAALLLLLRRDANL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 731 KELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMApySSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEH 810
Cdd:pfam00881 80 KLLLQDFLRGAPVLIVITASLSTYLRKAAERAYREALL--DAGAAAQNLLLAATSLGLGSCPIGGFDAAAVRELLGLPDD 157
|
170
....*....|.
gi 7106671 811 LDVVAYLCVGY 821
Cdd:pfam00881 158 ERLVGLIAVGY 168
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
58-505 |
6.29e-16 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 83.83 E-value: 6.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 58 APPAP----------EPVVETVHQP------GPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLGPPI----- 116
Cdd:PHA03247 2508 APPAPsrlapailpdEPVGEPVHPRmltwirGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVtsrar 2587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 117 -PDTSASPVRSLADRGPADAPvRHPGPPTACPEYLDVPQAAVPTPQAAA---PWGAQTAPQAQEVPVNAGAG-----HAE 187
Cdd:PHA03247 2588 rPDAPPQSARPRAPVDDRGDP-RGPAPPSPLPPDTHAPDPPPPSPSPAAnepDPHPPPTVPPPERPRDDPAPgrvsrPRR 2666
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 188 TVVPVPEQQAAEPVG-----AAQALVTRVATEA----------------VAATGGTPADAGESGEPQEAPAPEAAHTDAG 246
Cdd:PHA03247 2667 ARRLGRAAQASSPPQrprrrAARPTVGSLTSLAdpppppptpepaphalVSATPLPPGPAAARQASPALPAAPAPPAVPA 2746
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 247 WPVDPAEEAVPVPEAVPAVPVAPTAPvTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDE 326
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAGPPAPAPP-AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA 2825
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 327 PRVADDAPEAPAPQEAPSSLAPEPTP-GDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEA 405
Cdd:PHA03247 2826 GPLPPPTSAQPTAPPPPPGPPPPSLPlGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP 2905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 406 AQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSlmdatmqqeqeqeqeqeqeqEQEMAAVVVTDGTAGPV-AADAPATG 484
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP--------------------QPPLAPTTDPAGAGEPSgAVPQPWLG 2965
|
490 500
....*....|....*....|.
gi 7106671 485 AQEPAPVPAPVAQEPHPAQPV 505
Cdd:PHA03247 2966 ALVPGRVAVPRFRVPQPAPSR 2986
|
|
| PRK13294 |
PRK13294 |
F420-0--gamma-glutamyl ligase; Provisional |
639-828 |
2.19e-08 |
|
F420-0--gamma-glutamyl ligase; Provisional
Pssm-ID: 183957 [Multi-domain] Cd Length: 448 Bit Score: 58.10 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 639 APAYDDAERAAVLkvmrERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAmheLATRQRDAY 718
Cdd:PRK13294 246 AEALELGRREAVL----LRRSVRE-FSDDPVDPEAVRRAVAAALTAPAPHHTRPVRFVWLRSAAVRTR---LLDAMRDAW 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 719 AKSLpkgRAKQFKELKIEAIL-------DTPVNIVVTADPTrgGRHTLG----RHTQPQMAPYSSALAVENLWLAARAEG 787
Cdd:PRK13294 318 RADL---RADGLSEESIARRVrrgdilyDAPELVVPFLVPD--GAHSYPdarrTAAERTMFTVAVGAAVQNLLVALAVEG 392
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 7106671 788 LGVGWV-SFFDEREMVRA-LGLPEHLDVVAYLCVGYVDEFPDE 828
Cdd:PRK13294 393 LGSCWIgSTIFAADVVRAvLDLPADWEPLGAVAIGHPAEPPGP 435
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
228-432 |
1.62e-07 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 55.55 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 228 ESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTA----PVTEPVQATAEDDAGPEEALAVPEAQEVPAQS 303
Cdd:NF033839 282 DTPKEPGNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLekpkPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKP 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 304 APEEAPaEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTpgdaraVDAPVAAAEPEASAPEAAAPEPSVPE 383
Cdd:NF033839 362 KPEVKP-QPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPE------VKPQPEKPKPEVKPQPEKPKPEVKPQ 434
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 7106671 384 AAEPGPAPSPAPEQPAPvQVEAAQPTP-PEARPAPEAaphPQPDVQPAPQ 432
Cdd:NF033839 435 PEKPKPEVKPQPEKPKP-EVKPQPETPkPEVKPQPEK---PKPEVKPQPE 480
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
22-434 |
4.21e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 51.31 E-value: 4.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 22 PGVPAPGAYTYLSEATAEDEDLLLLPGA-QSAWGNEVAPPAPEPVVETVHQPGPhemsgrdsgsvdlggvrlPDPAQDSA 100
Cdd:pfam03154 146 PSIPSPQDNESDSDSSAQQQILQTQPPVlQAQSGAASPPSPPPPGTTQAATAGP------------------TPSAPSVP 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 101 TAPVPARRPlhlgPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVN 180
Cdd:pfam03154 208 PQGSPATSQ----PPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQ 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 181 AGAGHAETvvPVPEQQAAEPVGAAQALVtrvateavaATGGTPADAGESGEPQEAPAPEAAhtdAGWPVDPAEEAV-PVP 259
Cdd:pfam03154 284 TGPSHMQH--PVPPQPFPLTPQSSQSQV---------PPGPSPAAPGQSQQRIHTPPSQSQ---LQSQQPPREQPLpPAP 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 260 EAVPAVPVAPTAPVTE---------------PVQATAEDDAGPEEALA---------VPEAQEVPAQSAPEEAPAEVPAE 315
Cdd:pfam03154 350 LSMPHIKPPPTTPIPQlpnpqshkhpphlsgPSPFQMNSNLPPPPALKplsslsthhPPSAHPPPLQLMPQSQQLPPPPA 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 316 VPAQAPQGLDEPRVADDAPEAPAPQEAPSSlAPEPT----PGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAE-PGPA 390
Cdd:pfam03154 430 QPPVLTQSQSLPPPAASHPPTSGLHQVPSQ-SPFPQhpfvPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSgPVPA 508
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 7106671 391 PSPAPEQPAPVQVEAA-QPTPPEARPAPEAAPHPQPDVQPAPQPA 434
Cdd:pfam03154 509 AVSCPLPPVQIKEEALdEAEEPESPPPPPRSPSPEPTVVNTPSHA 553
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
194-438 |
4.66e-06 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 50.78 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 194 EQQAAEPVGAAqaLVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWP-VDPAEEAVPVPEAVPAVPVAPTAP 272
Cdd:NF033838 234 EEEAKRRADAK--LKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSdSSVGEETLPSPSLKPEKKVAEAEK 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 273 VTEPVQATAEDDAG------PEEALAVPEAQEVPAQSAPEEAPAEVpaeVPAQAPqgldEPRVADDAPEAPAPQEAPSSL 346
Cdd:NF033838 312 KVEEAKKKAKDQKEedrrnyPTNTYKTLELEIAESDVKVKEAELEL---VKEEAK----EPRNEEKIKQAKAKVESKKAE 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 347 AP--EPTPGDARAVDAPVAAAEPEASAPEAaapepsvPEAAEPGPAPSPAPEQPAPV-QVEAAQPTP----------PEA 413
Cdd:NF033838 385 ATrlEKIKTDRKKAEEEAKRKAAEEDKVKE-------KPAEQPQPAPAPQPEKPAPKpEKPAEQPKAekpadqqaeeDYA 457
|
250 260
....*....|....*....|....*
gi 7106671 414 RPAPEaAPHPQPDVQPaPQPAQGPQ 438
Cdd:NF033838 458 RRSEE-EYNRLTQQQP-PKTEKPAQ 480
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
316-439 |
8.21e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.22 E-value: 8.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 316 VPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAP---EPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPS 392
Cdd:NF040712 196 LRPLATVPRLAREPADARPEEVEPAPAAEGAPAtdsDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATR 275
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 7106671 393 PAPEQPAPVQ---VEAAQPTPPEAR-PAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:NF040712 276 DAGEPPAPGAaetPEAAEPPAPAPAaPAAPAAPEAEEPARPEPPPAPKPKR 326
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
218-351 |
8.57e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.22 E-value: 8.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 218 ATGGTPADAGESGEPQE-APAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEA 296
Cdd:NF040712 200 ATVPRLAREPADARPEEvEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGE 279
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 297 QEVPAQsAPEEAPAEVPAEVPAqAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPT 351
Cdd:NF040712 280 PPAPGA-AETPEAAEPPAPAPA-APAAPAAPEAEEPARPEPPPAPKPKRRRRRAS 332
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
213-536 |
9.63e-04 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 213 TEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAP--------TAPVTEPVQATAEDD 284
Cdd:NF033839 137 DEAVSKFEKDSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPdinqekekAKLAVATYMSKILDD 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 285 AGPEEALAVPEAQEVPAQSAPEEAPAEVPAEV----PAQAPQGLDEPRVADD-----------APEAPAPQEAPSSLAPE 349
Cdd:NF033839 217 IQKHHLQKEKHRQIVALIKELDELKKQALSEIdnvnTKVEIENTVHKIFADMdavvtkfkkglTQDTPKEPGNKKPSAPK 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 350 PtpgdarAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPvQVEAAQPTP-PEARPAPEAaphPQPDVQ 428
Cdd:NF033839 297 P------GMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKP-EVKPQLETPkPEVKPQPEK---PKPEVK 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 429 P---APQPAQGPQslmdatmqqEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQE--PHPAQ 503
Cdd:NF033839 367 PqpeKPKPEVKPQ---------PETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEvkPQPEK 437
|
330 340 350
....*....|....*....|....*....|...
gi 7106671 504 PVGQFLPVDGGQVPTTPHLAPTPPEAVLVPPET 536
Cdd:NF033839 438 PKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEK 470
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
285-422 |
3.90e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 40.91 E-value: 3.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 285 AGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAA 364
Cdd:NF040712 203 PRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPA 282
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 365 AEPEASAPEAAApepsvPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPH 422
Cdd:NF040712 283 PGAAETPEAAEP-----PAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRASVPS 335
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
133-271 |
6.46e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 40.14 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 133 ADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVA 212
Cdd:NF040712 192 FGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPD 271
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 213 TEAVAATGGTPADAGESGEPQEAPAPEAAhtdagwPVDPAEEAVPVPEAVPAVPVAPTA 271
Cdd:NF040712 272 EATRDAGEPPAPGAAETPEAAEPPAPAPA------APAAPAAPEAEEPARPEPPPAPKP 324
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
382-426 |
8.95e-03 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 40.37 E-value: 8.95e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 7106671 382 PEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPD 426
Cdd:COG5373 58 ATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPA 102
|
|
| |
|
Name |
Accession |
Description |
Interval |
E-value |
| CobT |
COG2038 |
NaMN:DMB phosphoribosyltransferase [Coenzyme transport and metabolism]; NaMN:DMB ... |
863-1212 |
2.64e-160 |
|
NaMN:DMB phosphoribosyltransferase [Coenzyme transport and metabolism]; NaMN:DMB phosphoribosyltransferase is part of the Pathway/BioSystem: Cobalamine/B12 biosynthesis
Pssm-ID: 441641 Cd Length: 351 Bit Score: 481.12 E-value: 2.64e-160
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 863 DLLAETVAQIRPLDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWP 942
Cdd:COG2038 2 SLLEETLPAIPPLDEEAMAAAQARLDNLTKPPGSLGRLEELAVQLAGIQGTLPPRLDRPA-VVVFAADHGVAAEGVSAYP 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 943 QEVTAQMVANFLGGGAVCNAFATQVGAEVCVVDVGVATDLPATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETA 1022
Cdd:COG2038 81 QEVTAQMVRNFLAGGAAINVLARQAGADLRVVDVGVAADLPPLPGLIDRKVARGTGNFAKGPAMTREEAEAALEAGIEIA 160
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1023 RDLVAAGNKALLTGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIG 1102
Cdd:COG2038 161 DELIAAGADLLGTGEMGIGNTTPAAALLAALTGLPPEEVVGRGTGLDDEGLARKIAVIRRALARHRPDPADPLDVLAKVG 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1103 GFEHAAMVGLLLGGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGT 1182
Cdd:COG2038 241 GFEIAAMAGAMLGAAARRVPVVVDGFISTAAALVAVRLAPGVRDYLIFSHRSAEPGHRLALEALGLEPLLDLGMRLGEGT 320
|
330 340 350
....*....|....*....|....*....|
gi 7106671 1183 GALLALPMVQSTARAMHEVATFDSAGVTEK 1212
Cdd:COG2038 321 GAALALPLLRAAVALLNEMATFEEAGVSGK 350
|
|
| DBI_PRT |
pfam02277 |
Phosphoribosyltransferase; This family of proteins represent the nicotinate-nucleotide- ... |
872-1206 |
7.07e-147 |
|
Phosphoribosyltransferase; This family of proteins represent the nicotinate-nucleotide- dimethylbenzimidazole phosphoribosyltransferase (NN:DBI PRT) enzymes involved in dimethylbenzimidazole synthesis. This function is essential to de novo cobalamin (vitamin B12) production in bacteria. Nicotinate mononucleotide (NaMN):5,6-dimethylbenzimidazole (DMB) phosphoribosyltransferase (CobT) from Salmonella enterica plays a central role in the synthesis of alpha-ribazole-5'-phosphate, an intermediate for the lower ligand of cobalamin.
Pssm-ID: 460520 Cd Length: 332 Bit Score: 445.29 E-value: 7.07e-147
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 872 IRPLDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVA 951
Cdd:pfam02277 1 IPPPDEEAMAAARARLDQLTKPLGSLGRLEELAVQLAGIQGTLPPPLDKKA-VVVFAGDHGVAAEGVSAYPQEVTAQMVA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 952 NFLGGGAVCNAFATQVGAEVCVVDVGVATDlpATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNK 1031
Cdd:pfam02277 80 NFLAGGAAINVLARQAGADLRVVDVGVDDD--DLPALINRKVRRGTGNFAKEPAMTREEAEAALEAGIELADELADAGAD 157
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1032 ALLTGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVG 1111
Cdd:pfam02277 158 LLGTGEMGIGNTTPAAALLAALTGLPPEEVTGRGTGLDDEGLARKIAVIRQALARHRPDPADPLDVLAKVGGFEIAAMAG 237
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1112 LLLGGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMV 1191
Cdd:pfam02277 238 AILGAAARRIPVVLDGFISTAAALVAVRLAPGVRDYLIASHRSAEPGHRLALEALGLEPLLDLGMRLGEGTGAALALPLL 317
|
330
....*....|....*
gi 7106671 1192 QSTARAMHEVATFDS 1206
Cdd:pfam02277 318 DAALALLNEMATFEE 332
|
|
| cobT_DBIPRT |
TIGR03160 |
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Members of this family ... |
876-1209 |
1.85e-141 |
|
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Members of this family are nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase, an enzyme of cobalamin biosynthesis. [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 274459 Cd Length: 333 Bit Score: 431.20 E-value: 1.85e-141
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 876 DAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFLG 955
Cdd:TIGR03160 1 DAEARAAAQARQDSLTKPPGSLGRLEELAVQLAGIQGTVPPRIDRPA-VVVFAGDHGVAAEGVSAFPQEVTAQMVENFLA 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 956 GGAVCNAFATQVGAEVCVVDVGVATDLPATPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALLT 1035
Cdd:TIGR03160 80 GGAAINVLARQAGADLRVVDVGVDHDLPEHPGLINRKVRRGTANIAQGPAMTREEAEAALEAGIEAADEAIDSGADLLGT 159
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1036 GEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLLG 1115
Cdd:TIGR03160 160 GEMGIGNTTPAAALLAALTGLPPEEVVGRGTGLDDEGLARKVAVIRRALERHRPNAGDPLDVLAKVGGFEIAAMAGAILG 239
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1116 GASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQSTA 1195
Cdd:TIGR03160 240 AAARRIPVLVDGFISTAAALVAVRLAPGVRDYLIASHRSAEPGHRAVLEALGLEPLLDLGMRLGEGTGAALALPLVRAAA 319
|
330
....*....|....
gi 7106671 1196 RAMHEVATFDSAGV 1209
Cdd:TIGR03160 320 AILNEMATFAEAGV 333
|
|
| cobT |
PRK00105 |
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed |
875-1211 |
1.57e-136 |
|
nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase; Reviewed
Pssm-ID: 234636 Cd Length: 335 Bit Score: 418.38 E-value: 1.57e-136
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 875 LDAKALGEAWERQKRMTKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFL 954
Cdd:PRK00105 1 PDAAAMAAAQARIDQLTKPPGSLGRLEELAVQLAGIQGTEPPRVERPA-VVVFAGDHGVAEEGVSAYPQEVTAQMVANFL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 955 GGGAVCNAFATQVGAEVCVVDVGVATDLPaTPGLLPRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALL 1034
Cdd:PRK00105 80 AGGAAINVLARQAGADLEVVDLGVDAPEP-LPGLINMRVARGTGNIAKEPAMTREEAEAALAAGAALADEAADAGTDLLG 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1035 TGEMGIANTTASAALISVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLL 1114
Cdd:PRK00105 159 VGEMGIGNTTPAAALVAALTGGDPEEVVGRGTGIDDAGLARKIAVVRRALARHRPALQDPLDVLAKVGGFEIAAMAGAIL 238
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1115 GGASLRTPVILDGVSAGAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQST 1194
Cdd:PRK00105 239 GAAVRRIPVLLDGFISTAAALVAVRLAPGVRDYLIFSHRSAEPGHRLALEHLGLEPLLDLGMRLGEGTGAALALPLVRAA 318
|
330
....*....|....*..
gi 7106671 1195 ARAMHEVATFDSAGVTE 1211
Cdd:PRK00105 319 VAFYNEMATFAEAGVSD 335
|
|
| DMB-PRT_CobT |
cd02439 |
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called ... |
891-1207 |
3.46e-121 |
|
Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT), also called CobT; Nicotinate-nucleotide-dimethylbenzimidazole phosphoribosyltransferase (DMB-PRT/CobT, not to be confused with the CobT subunit of cobaltochelatase, which does not belong to this group) catalyzes the synthesis of alpha-ribazole-5'-phosphate, from nicotinate mononucleotide (NAMN) and 5,6-dimethylbenzimidazole (DMB). This function is essential to the anaerobic biosynthesis pathway of cobalamin (vitamin B12), which is the largest and most complex cofactor in a number of enzyme-catalyzed reactions in bacteria, archaea and eukaryotes. Only eubacteria and archaebacteria can synthesize vitamin B12; multicellular organisms have lost this ability during evolution. DMB-PRT/CobT works sequentially with CobC (a phosphatase) to couple the lower ligand of cobalamin to a ribosyl moiety. DMB is the most common lower ligand of cobamides; other lower ligands include adenine, 5-methoxybenzimidazole or phenol. It has been suggested that earlier metabolic or enzymatic steps may control which lower ligand is available to DMB-PRT/CobT. In Salmonella enterica, for example, the lower ligand is DMB under aerobic conditions and adenine or 2-methyladenine under anaerobic conditions. Salmonella enterica DMB-PRT/CobT is a homodimer with two active sites, each active site is comprised of residues from both monomers. This group includes two distinct subfamilies, one archaeal-like, the other comprised of bacterial sequences.
Pssm-ID: 143332 Cd Length: 315 Bit Score: 376.83 E-value: 3.46e-121
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 891 TKPAGALGMLEIISAQLSGLSRQCPPPIPEPAaVAVFAGDHGVHAQGVTPWPQEVTAQMVANFLGGGAVCNAFATQVGAE 970
Cdd:cd02439 1 TKPLGSLGRLETLASQIAGIQGAGPPALPEKT-VLTFAADHGVAAEGVSAYPQEVTAQMVGNFPTGGAAINALARLAGAD 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 971 VCVVDVGVATDLPATPGLLpRKVRAGTSDMTTGTAMTREEAKQAIEVGIETARDLVAAGNKALLTGEMGIANTTASAALI 1050
Cdd:cd02439 80 LLVVDAGLAVDPPVPPILL-GKVRGGTANFAKGPAMTREEAEAALEAGIELAREALDSGYDLLVIGEMGIGNTTTAAAVL 158
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 1051 SVFTGADPAEVTGRGTGINDETLARKTEVVRRALELHQPDPADPIGVLAAIGGFEHAAMVGLLLGGASLRTPVILDGVSA 1130
Cdd:cd02439 159 AALGGDPAEEVSGRGTGLPDEGLERKIAVVEEALARNGPDPDDPLDVLAKVGGPEIAAMAGLILGAAARRVPVLLDGFIQ 238
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7106671 1131 GAAALVARAIAPEVLAACIAGHRSAEPGHVAALNKLGLRPLVDLDLRLGEGTGALLALPMVQSTARAMHEVATFDSA 1207
Cdd:cd02439 239 MAAALAAVRLAPDARDYLIATHRSVEPGHRLLLEALGLEPLLDLGMRLGEGTGAALALPLLRGAAAELNEMATFEEA 315
|
|
| BluB |
TIGR02476 |
5,6-dimethylbenzimidazole synthase; A previously published hypothesis that BluB, involved in ... |
642-847 |
1.62e-101 |
|
5,6-dimethylbenzimidazole synthase; A previously published hypothesis that BluB, involved in cobalamin biosynthesis, is EC 1.16.8.1 (cob(II)yrinic acid a,c-diamide reductase) is now contradicted by newer work ascribing a role in 5,6-dimethylbenzimidazole (DMB) biosynthesis. The BluB protein is related to the nitroreductase family (pfam0881). [Biosynthesis of cofactors, prosthetic groups, and carriers, Heme, porphyrin, and cobalamin]
Pssm-ID: 162875 Cd Length: 205 Bit Score: 319.77 E-value: 1.62e-101
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 642 YDDAERAAVLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKS 721
Cdd:TIGR02476 1 FSDAERAAVYRLIRERRDVRH-FRSDPVPEAVLERLLDAAHHAPSVGFSQPWRFVRVESPATREAVHALFTRANQAAAAI 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 722 LPKGRAKQFKELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREM 801
Cdd:TIGR02476 80 YDGERASQYHRLKLEGIREAPVQLAVFCDDARGEGHGLGRHTMPEMLRYSVACAIQNLWLAARAEGLGVGWVSILDPDAV 159
|
170 180 190 200
....*....|....*....|....*....|....*....|....*.
gi 7106671 802 VRALGLPEHLDVVAYLCVGYVDEFPDEPELMQAGWSKRRPLSWVVH 847
Cdd:TIGR02476 160 RRLLGVPEGWRLVAYLCLGWPDAFYDEPELERAGWQERRPLEWRRY 205
|
|
| BluB |
cd02145 |
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5, ... |
652-847 |
1.39e-97 |
|
5,6-dimethylbenzimidazole synthase; BluB catalyzes the O2-dependent conversion of FMNH2 to 5,6-dimethylbenzimidazole (DMB), a component of vitamin B12; is is a subfamily of the nitroreductase family; nitroreductases typically reduce their substrates by using NAD(P)H as electron donor and often use FMN as a cofactor.
Pssm-ID: 380321 Cd Length: 196 Bit Score: 308.90 E-value: 1.39e-97
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 652 KVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKSLPKGRAKQFK 731
Cdd:cd02145 2 RVIRWRRDVRH-FRPDPVPEEVLERLLQAAHLAPSVGLMQPWRFVRVRSAATRKAVHELFQRANAEAAEMYTGERAAQYR 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 732 ELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEHL 811
Cdd:cd02145 81 TLKLEGIEEAPLQLAVFCDRARAGGHGLGRTTMPEMDLYSSVCAVQNLWLAARAEGLGVGWVSILDPDEVKRLLGIPEHW 160
|
170 180 190
....*....|....*....|....*....|....*.
gi 7106671 812 DVVAYLCVGYVDEFPDEPELMQAGWSKRRPLSWVVH 847
Cdd:cd02145 161 EPVAYLCIGYPEFFYDEPELEQAGWEQRRPLEWVVF 196
|
|
| NfnB |
COG0778 |
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway ... |
650-846 |
1.69e-43 |
|
Nitroreductase [Energy production and conversion]; Nitroreductase is part of the Pathway/BioSystem: Pyrimidine degradation
Pssm-ID: 440541 [Multi-domain] Cd Length: 163 Bit Score: 155.40 E-value: 1.69e-43
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELatrqrdayakslpkgrakq 729
Cdd:COG0778 1 LLELLLTRRSVRK-FTDKPVSDEELEELLEAARLAPSAGNLQPWRFVVVRDPELRERLAEA------------------- 60
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 FKELKIEAILDTPVNIVVTADPTRGGRhtlgrhTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPE 809
Cdd:COG0778 61 LAEANQEWVADAPVLIVVCADPDRSEK------VPERYALLDAGIAAQNLLLAARALGLGTCWIGGFDPEKVRELLGLPE 134
|
170 180 190
....*....|....*....|....*....|....*..
gi 7106671 810 HLDVVAYLCVGYVDEFPDEpelmqagwSKRRPLSWVV 846
Cdd:COG0778 135 GEEPVALLALGYPAEELNP--------RPRKPLEEVV 163
|
|
| Nitroreductase |
pfam00881 |
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent ... |
654-821 |
6.80e-36 |
|
Nitroreductase family; The nitroreductase family comprises a group of FMN- or FAD-dependent and NAD(P)H-dependent enzymes able to metabolize nitrosubstituted compounds.
Pssm-ID: 425926 [Multi-domain] Cd Length: 168 Bit Score: 134.06 E-value: 6.80e-36
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 654 MRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELA---TRQRDAYAKSLPKGRAKQF 730
Cdd:pfam00881 1 IRQRRSVRK-FDPEPVPKEVLEEILEAARRAPSAGNLQPWRFYVVTDGELRYRLAEAAlelLLVEPAAALLLLLRRDANL 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 731 KELKIEAILDTPVNIVVTADPTRGGRHTLGRHTQPQMApySSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEH 810
Cdd:pfam00881 80 KLLLQDFLRGAPVLIVITASLSTYLRKAAERAYREALL--DAGAAAQNLLLAATSLGLGSCPIGGFDAAAVRELLGLPDD 157
|
170
....*....|.
gi 7106671 811 LDVVAYLCVGY 821
Cdd:pfam00881 158 ERLVGLIAVGY 168
|
|
| nitroreductase |
cd02139 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
650-849 |
2.41e-34 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380316 [Multi-domain] Cd Length: 165 Bit Score: 129.51 E-value: 2.41e-34
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRdayakslpkgrakq 729
Cdd:cd02139 1 VYEAIKKRRSIRK-YKPTPVEEEKLLRILEAARLAPSAKNRQPWRFIVVKDKELKEKLAEAANGQK-------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 fkelkieAILDTPVNIVVTADPTRGGrhtlgrhtQPQMAPYS---SALAVENLWLAARAEGLGVGWVSFFDEREMVRALG 806
Cdd:cd02139 66 -------FIAEAPVVIVACADPSESG--------MGCGKPYYlvdVAIAMEHLVLAATEEGLGTCWIGAFDEDKVKEILG 130
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 7106671 807 LPEHLDVVAYLCVGYVDEFPDEPElmqagwskRRPLSWVVHEE 849
Cdd:cd02139 131 IPEEYRVVALTPLGYPAEEPPPRP--------RKPLEEIVFYE 165
|
|
| Nitro_FMN_reductase |
cd02062 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
654-821 |
1.73e-32 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380311 [Multi-domain] Cd Length: 139 Bit Score: 123.18 E-value: 1.73e-32
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 654 MRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRdayakslpkgrakqfkel 733
Cdd:cd02062 1 IKTRRSIRK-FTDKPVPEEKLRKILEAARLAPSAGNLQPWRFIVVRDREKKEKLAKLAAPNQ------------------ 61
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 734 kiEAILDTPVNIVVTADPTRGGRHtlgrhtqpqmAPYSSALAVENLWLAARAEGLGVGWVSFFDERE-MVRA-LGLPEHL 811
Cdd:cd02062 62 --KFIAGAPVVIVVVADPDKSRPW----------ALEDAGAAAQNLLLAAAALGLGSCWIGGFDFREdKVRElLGIPENL 129
|
170
....*....|
gi 7106671 812 DVVAYLCVGY 821
Cdd:cd02062 130 RPVALIAIGY 139
|
|
| nitroreductase |
cd20608 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
651-821 |
1.44e-30 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380329 [Multi-domain] Cd Length: 145 Bit Score: 117.82 E-value: 1.44e-30
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 651 LKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAkslpkgrakqf 730
Cdd:cd20608 1 FEAIKTRRSVRR-FSDKPVEEEKLEKILEAARLAPSWANKQCWRFIVVTDKETLSELAKKESPSNGWLK----------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 731 kelkieailDTPVNIVVTADPTRGGRhtlgRHTQPQMApYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEH 810
Cdd:cd20608 69 ---------DAPVIIVVCADPKDSGW----LNGQNYYL-VDAAIAMQNLMLAATDLGLGTCWIGAFDEKKVKEILGIPEN 134
|
170
....*....|.
gi 7106671 811 LDVVAYLCVGY 821
Cdd:cd20608 135 IRVVALTPLGY 145
|
|
| nitroreductase |
cd20609 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
650-821 |
7.07e-27 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.
Pssm-ID: 380330 [Multi-domain] Cd Length: 145 Bit Score: 107.09 E-value: 7.07e-27
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAyakslpkgrakq 729
Cdd:cd20609 2 FLELAKKRYSVRK-FSDKPVEKEKLDKILEAGRLAPTAVNYQPQRILVVRSEEALEKLAKATPRFFGA------------ 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 fkelkieaildtPVNIVVTADPTRGGRHTLGRHtqpQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPE 809
Cdd:cd20609 69 ------------PLVIVVCYDKDESWKRPYDGK---DSGDIDAAIVATHMMLAATELGLGTCWVGNFDPEKVREAFNLPE 133
|
170
....*....|..
gi 7106671 810 HLDVVAYLCVGY 821
Cdd:cd20609 134 NLEPVAILPLGY 145
|
|
| YdjA-like |
cd02135 |
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the ... |
651-821 |
1.81e-24 |
|
nitroreductase family protein similar to Escherichia coli YdjA; A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to nitroreductase YdjA from Escherichia coli. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer. Members of this family are also called NADH dehydrogenase, oxygen-insensitive NAD(P)H nitrogenase or dihydropteridine reductase.
Pssm-ID: 380312 [Multi-domain] Cd Length: 162 Bit Score: 101.14 E-value: 1.81e-24
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 651 LKVMRERRDIRNGFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSadtrRAMHELATRQRDAYAKSLPKGRAKQF 730
Cdd:cd02135 1 LELIKTRRSIRKFKLTGAPPEEQLEELLEAAMWAPNHGKLEPWRFIVVTG----EGRERLAELLAAAAAARAPGADPEKL 76
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 731 KELKiEAILDTPVNIVVTADPTRGGRHTlgrhTQPQMApySSALAVENLWLAARAEGLGVGWVS--FFDEREMVRALGLP 808
Cdd:cd02135 77 EKAR-EKALRAPVVIAVVAKPDEDPKVP----EWEQYA--AVGAAVQNLLLAAHALGLGAVWRTgpVTYDPAVREALGLP 149
|
170
....*....|...
gi 7106671 809 EHLDVVAYLCVGY 821
Cdd:cd02135 150 EDERIVGFLYLGT 162
|
|
| nitroreductase |
cd20610 |
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or ... |
655-821 |
8.83e-22 |
|
nitroreductase family protein; Proteins of this family catalyze the reduction of flavin or nitrocompounds using NAD(P)H as electron donor in a obligatory two-electron transfer, utilizing FMN or FAD as cofactor. They are often found to be homodimers. Enzymes of this family are described as NAD(P)H:FMN oxidoreductases, oxygen-insensitive nitroreductase, flavin reductase P, dihydropteridine reductase, NADH oxidase or NADH dehydrogenase.
Pssm-ID: 380331 [Multi-domain] Cd Length: 167 Bit Score: 93.50 E-value: 8.83e-22
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 655 RERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKSLPKGRAKQFKE-- 732
Cdd:cd20610 2 KKRRSIRK-FKPDPVPKEDIEKILEAANWAPSGMNRQNWEFVVVKGGEKIEKIGISIKKKNEEIARLLEKVFAEKPIRfr 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 733 ---LKIEAILDTPVNIVVTADPTRGGRHtlgRHTQPQmapySSALAVENLWLAARAEGLGVGWVS--FFDEREMVRALGL 807
Cdd:cd20610 81 kfrRFFTLFGGAPVLVVVYTEPYKPPEE---RKPDLQ----SVSAAIQNLLLAAHALGLGTCWMTgpLYAEDEIEEILEI 153
|
170
....*....|....
gi 7106671 808 PEHLDVVAYLCVGY 821
Cdd:cd20610 154 PDDKELVAVTPLGY 167
|
|
| PnbA_NfnB-like |
cd02136 |
nitroreductase similar to Mycobacterium smegmatis NfnB; Members of this family utilize FMN as ... |
653-843 |
1.43e-18 |
|
nitroreductase similar to Mycobacterium smegmatis NfnB; Members of this family utilize FMN as a cofactor and catalyze reduction of a variety of nitroaromatic compounds, including nitrofurans, nitrobenzens, nitrophenol, nitrobenzoate and quinones by using either NADH or NADPH as a source of reducing equivalents in an obligatory two-election transfer mechanism. The enzyme is typically a homodimer. Mycobacterium smegmatis nitroreductase NfnB plays a role in resistance to benzothiazinone.
Pssm-ID: 380313 [Multi-domain] Cd Length: 152 Bit Score: 83.79 E-value: 1.43e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 653 VMRERRDIRnGFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSadtrramhelatrqrdayakslpkgraKQFKE 732
Cdd:cd02136 1 AIKSRRSVR-AFKDKPVPKETIEKILEAARRAPSGKNTQPWRVYVVTG---------------------------KARER 52
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 733 LKiEAILDTPVNIVVTADPtrggrhtlgrhTQPQMAPYSSALAVENLWLAARAEGLGVGW-VSFFDEREMVR-ALGLPEH 810
Cdd:cd02136 53 LK-KAFFGAPVALFLTMDK-----------VLGPWSWFDLGAFLQNLMLAAHALGLGTCPqGALAGYPDVVRkELGIPDD 120
|
170 180 190
....*....|....*....|....*....|...
gi 7106671 811 LDVVAYLCVGYvdefPDEPELMQAGWSKRRPLS 843
Cdd:cd02136 121 EELVCGIALGY----PDPDAPVNQFRTPREPLE 149
|
|
| nitroreductase |
cd02151 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
653-828 |
7.56e-18 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers..
Pssm-ID: 380326 [Multi-domain] Cd Length: 157 Bit Score: 81.81 E-value: 7.56e-18
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 653 VMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMhelatrqrdayakslpkGRAKQFKE 732
Cdd:cd02151 2 LLKKRRSIRK-YTDEPIEEEKLEEILEAALLAPSSRNSRPVEFIVVDDKETLKKL-----------------SECKPHGS 63
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 733 LKIEailDTPVNIVVTADPTRGGRHTlgrhtqpqmapYSSALAVENLWLAARAEGLGVGWVSFFDER--------EMVR- 803
Cdd:cd02151 64 AFLK---GAPAAIVVLADTEKSDTWI-----------EDASIAATYIQLAAESLGLGSCWIQIRNREtqdgktaeEYVRe 129
|
170 180
....*....|....*....|....*
gi 7106671 804 ALGLPEHLDVVAYLCVGYVDEFPDE 828
Cdd:cd02151 130 LLGIPENYRVLCIIALGYPDEEKPP 154
|
|
| nitroreductase |
cd02150 |
nitroreductase family protein; A subfamily of the nitroreductase family containing ... |
655-824 |
2.32e-17 |
|
nitroreductase family protein; A subfamily of the nitroreductase family containing uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.often found to be homodimers.
Pssm-ID: 380325 [Multi-domain] Cd Length: 156 Bit Score: 80.34 E-value: 2.32e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 655 RERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSadtRRAMHELATRQrdAYAKSLPkgrakqfkelk 734
Cdd:cd02150 2 LTRRSIRK-YTDKPVEEEDIEKLLRAAMAAPSAGNQQPWHFIVVTD---REKLDKIAEAH--PYGKMLK----------- 64
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 735 ieailDTPVNIVVTADPTrggrhtlgRHTQPQMAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRA----LGLPEH 810
Cdd:cd02150 65 -----EAPLAIVVCGDPS--------KEKAPGYWVQDCSAATENILLAAHALGLGAVWLGVYPFEERVKAireiLNIPEN 131
|
170
....*....|....
gi 7106671 811 LDVVAYLCVGYVDE 824
Cdd:cd02150 132 IIPFCVIALGYPAE 145
|
|
| TdsD-like |
cd02138 |
nitroreductase similar to Burkholderia pseudomallei TdsD; A subfamily of the nitroreductase ... |
653-847 |
6.86e-17 |
|
nitroreductase similar to Burkholderia pseudomallei TdsD; A subfamily of the nitroreductase family containing uncharacterized proteins that are similar to Burkholderia pseudomallei TdsD, may be involved in the processing of organosulfur compounds. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380315 [Multi-domain] Cd Length: 174 Bit Score: 79.51 E-value: 6.86e-17
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 653 VMRERRDIRnGFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVV-IRSADTRRAMHELATRQRDAYAKslpkgrakqfk 731
Cdd:cd02138 1 LIAERWSPR-AFSPEPISEEDLLSLFEAARWAPSCFNEQPWRFVVaRRDTEAFEKLLDLLAEGNQSWAK----------- 68
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 732 elkieailDTPVNIVVTADPTRgGRHTLGRHTqpqmAPYSSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPEHL 811
Cdd:cd02138 69 --------NAPVLIVVLAKTEF-DHNGKPNRY----ALFDTGAAVANLALQATALGLVVHQMAGFDPEKAKEALGIPDEY 135
|
170 180 190
....*....|....*....|....*....|....*....
gi 7106671 812 DVVAYLCVGYVDEFPDEPELMQAGW---SKRRPLSWVVH 847
Cdd:cd02138 136 EPITMIAIGYPGDPESLPEKLLEREeapRTRKPLSEIVF 174
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
58-505 |
6.29e-16 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 83.83 E-value: 6.29e-16
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 58 APPAP----------EPVVETVHQP------GPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLGPPI----- 116
Cdd:PHA03247 2508 APPAPsrlapailpdEPVGEPVHPRmltwirGLEELASDDAGDPPPPLPPAAPPAAPDRSVPPPRPAPRPSEPAVtsrar 2587
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 117 -PDTSASPVRSLADRGPADAPvRHPGPPTACPEYLDVPQAAVPTPQAAA---PWGAQTAPQAQEVPVNAGAG-----HAE 187
Cdd:PHA03247 2588 rPDAPPQSARPRAPVDDRGDP-RGPAPPSPLPPDTHAPDPPPPSPSPAAnepDPHPPPTVPPPERPRDDPAPgrvsrPRR 2666
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 188 TVVPVPEQQAAEPVG-----AAQALVTRVATEA----------------VAATGGTPADAGESGEPQEAPAPEAAHTDAG 246
Cdd:PHA03247 2667 ARRLGRAAQASSPPQrprrrAARPTVGSLTSLAdpppppptpepaphalVSATPLPPGPAAARQASPALPAAPAPPAVPA 2746
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 247 WPVDPAEEAVPVPEAVPAVPVAPTAPvTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDE 326
Cdd:PHA03247 2747 GPATPGGPARPARPPTTAGPPAPAPP-AAPAAGPPRRLTRPAVASLSESRESLPSPWDPADPPAAVLAPAAALPPAASPA 2825
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 327 PRVADDAPEAPAPQEAPSSLAPEPTP-GDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEA 405
Cdd:PHA03247 2826 GPLPPPTSAQPTAPPPPPGPPPPSLPlGGSVAPGGDVRRRPPSRSPAAKPAAPARPPVRRLARPAVSRSTESFALPPDQP 2905
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 406 AQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSlmdatmqqeqeqeqeqeqeqEQEMAAVVVTDGTAGPV-AADAPATG 484
Cdd:PHA03247 2906 ERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRP--------------------QPPLAPTTDPAGAGEPSgAVPQPWLG 2965
|
490 500
....*....|....*....|.
gi 7106671 485 AQEPAPVPAPVAQEPHPAQPV 505
Cdd:PHA03247 2966 ALVPGRVAVPRFRVPQPAPSR 2986
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
95-534 |
3.66e-15 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 81.14 E-value: 3.66e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 95 PAQDSATAPVPARRPLHLGPPIPDTSASPVRsLADRGPADAPVRHPGPPT-----------ACPEYLDVPQAAVPTPQAA 163
Cdd:PHA03247 2484 AEARFPFAAGAAPDPGGGGPPDPDAPPAPSR-LAPAILPDEPVGEPVHPRmltwirgleelASDDAGDPPPPLPPAAPPA 2562
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 164 APWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQalvtRVATEAVAATGGTPADAGESGEPQEAPAPEAAHT 243
Cdd:PHA03247 2563 APDRSVPPPRPAPRPSEPAVTSRARRPDAPPQSARPRAPVDD----RGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEP 2638
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 244 DAGWPVDPAEEAVPVPEAVP------------AVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAE 311
Cdd:PHA03247 2639 DPHPPPTVPPPERPRDDPAPgrvsrprrarrlGRAAQASSPPQRPRRRAARPTVGSLTSLADPPPPPPTPEPAPHALVSA 2718
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 312 VPAE-VPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPA 390
Cdd:PHA03247 2719 TPLPpGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRRLTRPAVASLSESRESL 2798
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 391 PSPAPEQPAPVQVEAAQPT-PPEARPAPEAAPHPQPdvQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVT 469
Cdd:PHA03247 2799 PSPWDPADPPAAVLAPAAAlPPAASPAGPLPPPTSA--QPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPA 2876
|
410 420 430 440 450 460
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 470 DGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDGGQVPTTPHLAPTPPEAVLVPP 534
Cdd:PHA03247 2877 APARPPVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQPPPPPPPRPQP 2941
|
|
| MhqN-like |
cd02137 |
nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN; A diverse subfamily ... |
651-843 |
3.78e-15 |
|
nitroreductase family protein similar to the NAD(P)H nitroreductase MhqN; A diverse subfamily of the nitroreductase family containing uncharacterized proteins; includes nitroreductases MhqN, YodC, YdgI, DrgA. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380314 [Multi-domain] Cd Length: 147 Bit Score: 73.81 E-value: 3.78e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 651 LKVMRERRDIRNgFRSD-PIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRdayakslpkgrakq 729
Cdd:cd02137 1 LEVIKSRRSVRN-FDPDhKIPKEELKEILELATLAPSSFNLQPWRFVVVRDPELKAKLAEAAYNQP-------------- 65
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 fkelkieAILDTPVNIVVTADPtrggrhtlgrhtqpqmapySSALAVENLWLAARAEGLGVGWVSFFDEREMVRALGLPE 809
Cdd:cd02137 66 -------QVTTASAVILVLGDL-------------------NAGLAAMNLMLAAKAKGYDTCPMGGFDKEKVAELLNLPD 119
|
170 180 190
....*....|....*....|....*....|....
gi 7106671 810 HLDVVAYLCVGYVDEfPDEPelmqagwSKRRPLS 843
Cdd:cd02137 120 RYVPVLLIAIGKAAD-KAPR-------SGRLPVD 145
|
|
| iodotyrosine_dehalogenase |
cd02144 |
iodotyrosine dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the ... |
650-843 |
9.51e-15 |
|
iodotyrosine dehalogenase; Iodotyrosine dehalogenase catalyzes the removal of iodine from the 3, 5 positions of L-tyosine in thyroid, liver and kidney, using NADPH as electron donor. This enzyme is a homolog of the nitroreductase family. These enzymes are usually homodimers.
Pssm-ID: 380320 Cd Length: 192 Bit Score: 74.11 E-value: 9.51e-15
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRnGFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATR-QRDAYAKSLPKGRAK 728
Cdd:cd02144 1 FYELMKKRRSVR-DFSSEPVPREVIENAIRTAGTAPSGANTQPWTFVVVSDPEIKRKIREAAEEeEKEFYEKRMGEEWVW 79
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 729 QFKELKIEAI---LDT-PVNIVVTADptrggRHTLGRHTQPQMAPY---SSALAVENLWLAARAEGLG--------VGWV 793
Cdd:cd02144 80 DLKPLGTNWEkpyLTEaPYLIVVFKQ-----KYGVLPDGKKKKHYYneeSVGIAVGILLAALHNAGLVtlthtpspMPFL 154
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 7106671 794 sffdeREMvraLGLPEHLDVVAYLCVGYVDEFPDEPELmqagwsKRRPLS 843
Cdd:cd02144 155 -----RDL---LGRPKNEKPLLLLPVGYPAEDATVPDL------KRKPLE 190
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
171-439 |
3.03e-13 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 74.50 E-value: 3.03e-13
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 171 APQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGwpvD 250
Cdd:PRK07003 361 AVTGGGAPGGGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATA---D 437
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 251 PAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAvpEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVA 330
Cdd:PRK07003 438 RGDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASA--PASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAA 515
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 331 DDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEP----EASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAA 406
Cdd:PRK07003 516 ASREDAPAAAAPPAPEARPPTPAAAAPAARAGGAAAAldvlRNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQ 595
|
250 260 270
....*....|....*....|....*....|...
gi 7106671 407 QPTPPEARPAPEAAPHPqpdVQPAPQPAQGPQS 439
Cdd:PRK07003 596 VPTPRARAATGDAPPNG---AARAEQAAESRGA 625
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
93-437 |
1.30e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 72.33 E-value: 1.30e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 93 PDPAQDSATAPVPARRPLHLGPPIPdTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAP 172
Cdd:PRK07764 413 AAAAPAAAAAPAPAAAPQPAPAPAP-APAPPSPAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPA 491
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 173 QAQEVPVNAGAGHAETVVPVPEQQAAEPVGA-------------AQALVTRVATEAVAATGGTPADAGESGEPQEAP--- 236
Cdd:PRK07764 492 AAPAAPAAPAAPAGADDAATLRERWPEILAAvpkrsrktwaillPEATVLGVRGDTLVLGFSTGGLARRFASPGNAEvlv 571
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 237 --------------APEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQ 302
Cdd:PRK07764 572 talaeelggdwqveAVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPE 651
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 303 SAPEEAPAEVPAEVPAQAPQGLDEPRVADDAP-----------EAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASA 371
Cdd:PRK07764 652 HHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPapapaapaapaGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAP 731
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7106671 372 PEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVeAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGP 437
Cdd:PRK07764 732 SPAADDPVPLPPEPDDPPDPAGAPAQPPPPPA-PAPAAAPAAAPPPSPPSEEEEMAEDDAPSMDDE 796
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
99-503 |
2.63e-12 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 71.56 E-value: 2.63e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 99 SATAPVPARRPLHLGPPIPDTSASPVRSladRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPwGAQTAPQAQEVP 178
Cdd:PRK07764 372 RGLLARLERLERRLGVAGGAGAPAAAAP---SAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAP-APAPAPPSPAGN 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 179 VNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWP--------VD 250
Cdd:PRK07764 448 APAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATLRERWPeilaavpkRS 527
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 251 PAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPE-------------------EALAVPEAQEVPAQSAPEEAPAE 311
Cdd:PRK07764 528 RKTWAILLPEATVLGVRGDTLVLGFSTGGLARRFASPGnaevlvtalaeelggdwqvEAVVGPAPGAAGGEGPPAPASSG 607
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 312 VPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAP 391
Cdd:PRK07764 608 PPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAAPPPAPAP 687
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 392 SPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDG 471
Cdd:PRK07764 688 AAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPA 767
|
410 420 430
....*....|....*....|....*....|..
gi 7106671 472 TAGPVAADAPATGAQEPAPVPAPVAQEPHPAQ 503
Cdd:PRK07764 768 AAPAAAPPPSPPSEEEEMAEDDAPSMDDEDRR 799
|
|
| nitroreductase_FeS-like |
cd02143 |
nitroreductases with an N-terminal iron-sulfur cluster-binding domain; Members of this family ... |
654-821 |
3.82e-12 |
|
nitroreductases with an N-terminal iron-sulfur cluster-binding domain; Members of this family utilize FMN as a cofactor. This family may be involved in the reduction of flavin or nitroaromatic compounds via an obligatory two-electron transfer. Nitroreductase is homodimer. Each subunit contains one FMN molecule.
Pssm-ID: 380319 [Multi-domain] Cd Length: 187 Bit Score: 66.34 E-value: 3.82e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 654 MRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRDAYAKSLPKGRAKQFKEL 733
Cdd:cd02143 2 LRSRRSIRR-YKDKPVPRETLEKLLDIARYAPTGHNSQPVHWLVVDDPEKVRRLAELVIDWMRELIKEDPELAGKLFLDG 80
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 734 KIEA-------IL-DTPVNIVVTADptRGGRhtlgrhtqpqMAPYSSALAVENLWLAARAEGLGVGWVSFF-----DERE 800
Cdd:cd02143 81 IVAAwekgidvILrGAPHLVVAHAP--KDAP----------TPPVDCAIALTYLELAAPSLGLGTCWAGFFtaaanNYPP 148
|
170 180
....*....|....*....|.
gi 7106671 801 MVRALGLPEHLDVVAYLCVGY 821
Cdd:cd02143 149 LREALGLPEGHKVGGAMMLGY 169
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
227-440 |
4.01e-12 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 70.68 E-value: 4.01e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 227 GESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPE 306
Cdd:PRK12323 370 GGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGPGGAPA 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 307 EAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPtpgdaravdapvaaAEPEASAPEAAAPEPSVPEAAE 386
Cdd:PRK12323 450 PAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPAD--------------DDPPPWEELPPEFASPAPAQPD 515
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 7106671 387 PGPAPSPAPEQPAPVQVEAAQPTPPeARPAPEAAPHPQPDVQPAPQPAQGPQSL 440
Cdd:PRK12323 516 AAPAGWVAESIPDPATADPDDAFET-LAPAPAAAPAPRAAAATEPVVAPRPPRA 568
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
157-343 |
4.20e-12 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 70.84 E-value: 4.20e-12
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 157 VPTPQAAAPWGAQTAPQAQEVPVnagaghAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADagesgEPQEAP 236
Cdd:PRK10811 847 VVRPQDVQVEEQREAEEVQVQPV------VAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEV-----VVVETT 915
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 237 APE---AAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAE-DDAGPEEALAVPEAQEVPAQSAPEEAPAEV 312
Cdd:PRK10811 916 HPEviaAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAEtAEVVVAEPEVVAQPAAPVVAEVAAEVETVT 995
|
170 180 190
....*....|....*....|....*....|....*
gi 7106671 313 PAEVPAQAPQGLDEPRVADDA----PEAPAPQEAP 343
Cdd:PRK10811 996 AVEPEVAPAQVPEATVEHNHAtapmTRAPAPEYVP 1030
|
|
| nitroreductase |
cd03370 |
uncharacterized nitroreductase family proteins; Nitroreductase family containing Thermus ... |
654-824 |
1.21e-11 |
|
uncharacterized nitroreductase family proteins; Nitroreductase family containing Thermus thermophilus NADH oxidase and other, uncharacterized proteins. Nitroreductase catalyzes the reduction of nitroaromatic compounds such as nitrotoluenes, nitrofurans and nitroimidazoles. This process requires NAD(P)H as electron donor in an obligatory two-electron transfer and uses FMN as cofactor. The enzyme is typically a homodimer.
Pssm-ID: 380327 [Multi-domain] Cd Length: 191 Bit Score: 65.03 E-value: 1.21e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 654 MRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQrdayakslpkgraKQfkel 733
Cdd:cd03370 5 IESRRSIRK-YTQEPVPDEDLREILRLAGLAPSAWNIQPWRFVVVRDAELKEQLQAAAYGQ-------------AQ---- 66
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 734 kieaILDTPVNIVVTAD-------------PTRGG----------RHTLGRHTQPQMAPYSSA---LAVENLWLAARAEG 787
Cdd:cd03370 67 ----VTSAPAVIVIYSDmedalanleetihPGLSEerrqreaaglRGAFGKMSVEQRGQWGLAqanIALGFLLLAAQSLG 142
|
170 180 190
....*....|....*....|....*....|....*...
gi 7106671 788 LGVGWVSFFDErEMVRA-LGLPEHLDVVAYLCVGYVDE 824
Cdd:cd03370 143 YDTSPMLGFDP-EKVKAlLGLPEHVTIAALVALGKPAE 179
|
|
| NfsA-like |
cd02146 |
nitroreductase similar to Escherichia coli NfsA; This family contains NADPH-dependent flavin ... |
650-851 |
2.26e-11 |
|
nitroreductase similar to Escherichia coli NfsA; This family contains NADPH-dependent flavin reductase and oxygen-insensitive nitroreductase. These enzymes are homodimeric flavoproteins that contain one FMN per monomer as a cofactor. Flavin reductase catalyzes the reduction of flavin by using NADPH as an electron donor. Oxygen-insensitive nitroreductase, such as NfsA protein in Escherichia coli, catalyzes reduction of nitrocompounds using NADPH as electron donor.
Pssm-ID: 380322 [Multi-domain] Cd Length: 229 Bit Score: 64.95 E-value: 2.26e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQRdaYAKSLPK----- 724
Cdd:cd02146 1 TIETILNHRSVRK-FTDEPLTDETLETLIAAAQSASTSSNLQAYSVIVVTDPELREKLAELAGNQP--YVAQAPVflvfc 77
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 725 ---GRAKQFKEL--KIEAILDTPVNIVVTADPTrggrhtlgrhtqpqmapyssALAVENLWLAARAEGLGVGWVSFF--D 797
Cdd:cd02146 78 adlYRHQKIAEEagGKDVGLDYLESFLVGVVDA--------------------ALAAQNALVAAESLGLGIVYIGGIrnN 137
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 798 EREMVRALGLPEHLDVVAYLCVGYVDEFPD-EPelmqagwskRRPLSWVVHEETY 851
Cdd:cd02146 138 PEEVIELLGLPEYVFPLFGLTVGHPDPTPEvKP---------RLPLEAVVHEETY 183
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
202-533 |
2.74e-11 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 68.09 E-value: 2.74e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 202 GAAQALVTRV-ATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPvpeavPAVPVAPTAPVTEPVQAT 280
Cdd:PRK07764 369 DDERGLLARLeRLERRLGVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAP-----AAAPQPAPAPAPAPAPPS 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 281 AEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLA------PE----- 349
Cdd:PRK07764 444 PAGNAPAGGAPSPPPAAAPSAQPAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAAtlrerwPEilaav 523
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 350 -----------------------------PTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAP 400
Cdd:PRK07764 524 pkrsrktwaillpeatvlgvrgdtlvlgfSTGGLARRFASPGNAEVLVTALAEELGGDWQVEAVVGPAPGAAGGEGPPAP 603
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 401 VQveaAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADA 480
Cdd:PRK07764 604 AS---SGPPEEAARPAAPAAPAAPAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDASDGGDGWPAKAGGAAPAA 680
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|...
gi 7106671 481 PATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDGGQVPTTPHLAPTPPEAVLVP 533
Cdd:PRK07764 681 PPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQAAQGASAPSP 733
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
300-513 |
3.67e-11 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 67.59 E-value: 3.67e-11
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 300 PAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEP 379
Cdd:PRK12323 365 PGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQASARGP 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 380 SVPEAAEPGPAPSPAPEQPAPvqveaAQPTPPEARPAPEAAPHPQPDVQPAPQPaQGPQSLMDATMQQEQEQEQEQEQEQ 459
Cdd:PRK12323 445 GGAPAPAPAPAAAPAAAARPA-----AAGPRPVAAAAAAAPARAAPAAAPAPAD-DDPPPWEELPPEFASPAPAQPDAAP 518
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....
gi 7106671 460 EQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDG 513
Cdd:PRK12323 519 AGWVAESIPDPATADPDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASG 572
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
232-641 |
1.08e-10 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 66.50 E-value: 1.08e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 232 PQEAPAPEAAHT--DAGWPVDPAEEAVPVPeAVPAVPVAPTAPVTEPV-----------QATAEDDAGPEEALAVPEAQE 298
Cdd:PHA03247 2483 PAEARFPFAAGAapDPGGGGPPDPDAPPAP-SRLAPAILPDEPVGEPVhprmltwirglEELASDDAGDPPPPLPPAAPP 2561
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 299 -VPAQSAPEEAPAEVPAEVPAQ-------APQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEAS 370
Cdd:PHA03247 2562 aAPDRSVPPPRPAPRPSEPAVTsrarrpdAPPQSARPRAPVDDRGDPRGPAPPSPLPPDTHAPDPPPPSPSPAANEPDPH 2641
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 371 APEAAAPEPSVPEAAEPGPAPSP----APEQPAPVQVEAAQPTPPEARP-----APEAAPHPQPDV-QPAPQPAQGPQSL 440
Cdd:PHA03247 2642 PPPTVPPPERPRDDPAPGRVSRPrrarRLGRAAQASSPPQRPRRRAARPtvgslTSLADPPPPPPTpEPAPHALVSATPL 2721
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 441 MDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPH-----PAQPVGQFLPVDGGQ 515
Cdd:PHA03247 2722 PPGPAAARQASPALPAAPAPPAVPAGPATPGGPARPARPPTTAGPPAPAPPAAPAAGPPRrltrpAVASLSESRESLPSP 2801
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 516 VPTTPHLAPTPPEAVLVPPETAAEPEPV---AAAPAAEEAVAPVPAPREADPELVQSVDDLDTRGAEEDDHAAEAAEAAE 592
Cdd:PHA03247 2802 WDPADPPAAVLAPAAALPPAASPAGPLPpptSAQPTAPPPPPGPPPPSLPLGGSVAPGGDVRRRPPSRSPAAKPAAPARP 2881
|
410 420 430 440
....*....|....*....|....*....|....*....|....*....
gi 7106671 593 AAEETAEAVGATASDPASQEAPAPQEAPHDGSSGGAAEAPRPVGPAAPA 641
Cdd:PHA03247 2882 PVRRLARPAVSRSTESFALPPDQPERPPQPQAPPPPQPQPQPPPPPQPQ 2930
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
152-536 |
2.75e-10 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 65.01 E-value: 2.75e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 152 VPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGE 231
Cdd:PRK07764 386 GVAGGAGAPAAAAPSAAAAAPAAAPAPAAAAPAAAAAPAPAAAPQPAPAPAPAPAPPSPAGNAPAGGAPSPPPAAAPSAQ 465
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 232 PQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPV-------------------------QATAEDDAG 286
Cdd:PRK07764 466 PAPAPAAAPEPTAAPAPAPPAAPAPAAAPAAPAAPAAPAGADDAATlrerwpeilaavpkrsrktwaillpEATVLGVRG 545
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 287 PEEALAVPEAQEVPAQSAPEEApaEVPAEVPAQAPQGLDEPR-VADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAA 365
Cdd:PRK07764 546 DTLVLGFSTGGLARRFASPGNA--EVLVTALAEELGGDWQVEaVVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAA 623
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 366 EPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQvEAAQPTPPEARPAPEAAPHPQPdvqPAPQPAQGPQSLMDATM 445
Cdd:PRK07764 624 PAAPAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVP-DASDGGDGWPAKAGGAAPAAPP---PAPAPAAPAAPAGAAPA 699
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 446 QQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDGGQVPTTPHLAPT 525
Cdd:PRK07764 700 QPAPAPAATPPAGQADDPAAQPPQAAQGASAPSPAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPP 779
|
410
....*....|.
gi 7106671 526 PPEAVLVPPET 536
Cdd:PRK07764 780 SEEEEMAEDDA 790
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
248-423 |
3.99e-10 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 64.29 E-value: 3.99e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 248 PVDPAEEAVPVPeAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQaPQGLDEP 327
Cdd:PRK10811 857 EQREAEEVQVQP-VVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQ-PQVITES 934
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 328 RVADDAPEAPAPQEA-PSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAA 406
Cdd:PRK10811 935 DVAVAQEVAEHAEPVvEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHN 1014
|
170
....*....|....*...
gi 7106671 407 QPTPPEAR-PAPEAAPHP 423
Cdd:PRK10811 1015 HATAPMTRaPAPEYVPEA 1032
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
132-313 |
4.27e-10 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 64.29 E-value: 4.27e-10
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 132 PADAPV---RHPGPPTACPEYLDVPQAAVPTPQAAAPwGAQTAPQAQEVPVNAGAGHAETVVPVPEQQ---AAEPVgAAQ 205
Cdd:PRK10811 850 PQDVQVeeqREAEEVQVQPVVAEVPVAAAVEPVVSAP-VVEAVAEVVEEPVVVAEPQPEEVVVVETTHpevIAAPV-TEQ 927
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 206 ALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDagwPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDA 285
Cdd:PRK10811 928 PQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETA---EVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPA 1004
|
170 180
....*....|....*....|....*...
gi 7106671 286 GPEEALAVPEAQEVPAQSAPeeAPAEVP 313
Cdd:PRK10811 1005 QVPEATVEHNHATAPMTRAP--APEYVP 1030
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
248-431 |
1.16e-09 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 62.75 E-value: 1.16e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 248 PVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEddagPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPqgldep 327
Cdd:PRK10811 850 PQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVS----APVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEV------ 919
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 328 rVADDAPEAPAPQEAPSSLAPEPTPGDARAVdaPVAAAEPEASAPEAAAPEPSVpeaAEPGPAPSPAPEQPAPVQVEAAQ 407
Cdd:PRK10811 920 -IAAPVTEQPQVITESDVAVAQEVAEHAEPV--VEPQDETADIEEAAETAEVVV---AEPEVVAQPAAPVVAEVAAEVET 993
|
170 180 190
....*....|....*....|....*....|....*....
gi 7106671 408 PTPPEARPAPEA------------APH---PQPDVQPAP 431
Cdd:PRK10811 994 VTAVEPEVAPAQvpeatvehnhatAPMtraPAPEYVPEA 1032
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
132-351 |
1.29e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 62.59 E-value: 1.29e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 132 PADAPVRHPGPPTAcpeyldVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAghaetvvPVPEQQAAEPVGAAQALVTRV 211
Cdd:PRK12323 377 AAAAPVAQPAPAAA------APAAAAPAPAAPPAAPAAAPAAAAAARAVAAA-------PARRSPAPEALAAARQASARG 443
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 212 ATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPeAVPAVPVAPTAPVTEPVQATAEDDAGPEEAL 291
Cdd:PRK12323 444 PGGAPAPAPAPAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAP-ADDDPPPWEELPPEFASPAPAQPDAAPAGWV 522
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106671 292 AVPEAQEVPAQ-SAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPT 351
Cdd:PRK12323 523 AESIPDPATADpDDAFETLAPAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDGDWPA 583
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
199-504 |
9.63e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.86 E-value: 9.63e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 199 EPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAgwpvdPAEEAVPVPEAVPAVPVAPTAPvtepvQ 278
Cdd:PRK07003 344 EYAGFTMTLLRMLAFEPAVTGGGAPGGGVPARVAGAVPAPGARAAAA-----VGASAVPAVTAVTGAAGAALAP-----K 413
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 279 ATAEDDAGPEEAlavPEAQEVPAQSAPE-EAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARA 357
Cdd:PRK07003 414 AAAAAAATRAEA---PPAAPAPPATADRgDDAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAAF 490
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 358 VDAPvaaaepeasapeaaapepsvPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPhPQPDVQPAPQPAQGP 437
Cdd:PRK07003 491 EPAP--------------------RAAAPSAATPAAVPDARAPAAASREDAPAAAAPPAPEARP-PTPAAAAPAARAGGA 549
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 7106671 438 QSLMDATmqqeqeqeqeqeqeQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQP 504
Cdd:PRK07003 550 AAALDVL--------------RNAGMRVSSDRGARAAAAAKPAAAPAAAPKPAAPRVAVQVPTPRAR 602
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
100-350 |
9.72e-09 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 59.86 E-value: 9.72e-09
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 100 ATAPVPARRPLHLGPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPV 179
Cdd:PRK07003 370 GGVPARVAGAVPAPGARAAAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGDDAADGDAPV 449
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 180 NAGAGHAETVVPVPEQQAAEPVGAAQAlvtrvateAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVP 259
Cdd:PRK07003 450 PAKANARASADSRCDERDAQPPADSGS--------ASAPASDAPPDAAFEPAPRAAAPSAATPAAVPDARAPAAASREDA 521
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 260 EAVPAVPvAPTAPVTEPVQATAEDDAGPEEA---------LAVPEAQEVPAQSAPEEAPAEVPAE--------VPAQAPQ 322
Cdd:PRK07003 522 PAAAAPP-APEARPPTPAAAAPAARAGGAAAaldvlrnagMRVSSDRGARAAAAAKPAAAPAAAPkpaaprvaVQVPTPR 600
|
250 260
....*....|....*....|....*...
gi 7106671 323 GLDEPRVADDAPEAPAPQEAPSSLAPEP 350
Cdd:PRK07003 601 ARAATGDAPPNGAARAEQAAESRGAPPP 628
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
191-416 |
1.02e-08 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 59.67 E-value: 1.02e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 191 PVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESgepqeAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAV-PVAP 269
Cdd:PRK10811 846 PVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVS-----APVVEAVAEVVEEPVVVAEPQPEEVVVVETThPEVI 920
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 270 TAPVTEPVQATAEDDA--GPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLA 347
Cdd:PRK10811 921 AAPVTEQPQVITESDVavAQEVAEHAEPVVEPQDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPE 1000
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 348 PEPTPgdaravdapvaaaepeasapeaaapepSVPEAAEPGPAPSPAPEQPAPvqveAAQPTPPEA----RPA 416
Cdd:PRK10811 1001 VAPAQ---------------------------VPEATVEHNHATAPMTRAPAP----EYVPEAPRHsdwqRPT 1042
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
198-413 |
1.07e-08 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 59.50 E-value: 1.07e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 198 AEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAA---HTDAGWPVDPAEEAVPV-----PEAVPAVPVAP 269
Cdd:PRK12323 372 AGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAaraVAAAPARRSPAPEALAAarqasARGPGGAPAPA 451
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 270 TAPVTEPVQATAEDDAGPEEALAVpeAQEVPAQSAPEEAPAEVPAEVPaqaPQGLDEPRVADDAPEAPAPQEAPSSLAPE 349
Cdd:PRK12323 452 PAPAAAPAAAARPAAAGPRPVAAA--AAAAPARAAPAAAPAPADDDPP---PWEELPPEFASPAPAQPDAAPAGWVAESI 526
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7106671 350 PTPGDARAVDAPvaaaepeasapeaaapepsvpEAAEPGPAPSPAPEQPAPVQVEAAqPTPPEA 413
Cdd:PRK12323 527 PDPATADPDDAF---------------------ETLAPAPAAAPAPRAAAATEPVVA-PRPPRA 568
|
|
| PRK13294 |
PRK13294 |
F420-0--gamma-glutamyl ligase; Provisional |
639-828 |
2.19e-08 |
|
F420-0--gamma-glutamyl ligase; Provisional
Pssm-ID: 183957 [Multi-domain] Cd Length: 448 Bit Score: 58.10 E-value: 2.19e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 639 APAYDDAERAAVLkvmrERRDIRNgFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAmheLATRQRDAY 718
Cdd:PRK13294 246 AEALELGRREAVL----LRRSVRE-FSDDPVDPEAVRRAVAAALTAPAPHHTRPVRFVWLRSAAVRTR---LLDAMRDAW 317
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 719 AKSLpkgRAKQFKELKIEAIL-------DTPVNIVVTADPTrgGRHTLG----RHTQPQMAPYSSALAVENLWLAARAEG 787
Cdd:PRK13294 318 RADL---RADGLSEESIARRVrrgdilyDAPELVVPFLVPD--GAHSYPdarrTAAERTMFTVAVGAAVQNLLVALAVEG 392
|
170 180 190 200
....*....|....*....|....*....|....*....|...
gi 7106671 788 LGVGWV-SFFDEREMVRA-LGLPEHLDVVAYLCVGYVDEFPDE 828
Cdd:PRK13294 393 LGSCWIgSTIFAADVVRAvLDLPADWEPLGAVAIGHPAEPPGP 435
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
153-322 |
3.63e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 57.57 E-value: 3.63e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 153 PQAAVPTPQAAAPwGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEP 232
Cdd:PRK07994 361 PAAPLPEPEVPPQ-SAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAK 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 233 QEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPV---TEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAP 309
Cdd:PRK07994 440 KSEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRwkaTNPVEVKKEPVATPKALKKALEHEKTPELAAKLAAE 519
|
170
....*....|...
gi 7106671 310 AEVPAEVPAQAPQ 322
Cdd:PRK07994 520 AIERDPWAALVSQ 532
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
235-523 |
4.31e-08 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 57.79 E-value: 4.31e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 235 APAPEAAHTDAGwPVDPAEEAVPVP--EAVPAVPV-----APTAPVTEPVQATAEDDAGPEEALAVPEAQevpaQSAPEE 307
Cdd:PRK10263 324 AAATTATQSWAA-PVEPVTQTPPVAsvDVPPAQPTvawqpVPGPQTGEPVIAPAPEGYPQQSQYAQPAVQ----YNEPLQ 398
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 308 APaeVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEP 387
Cdd:PRK10263 399 QP--VQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQSTFAPQSTYQTEQTYQQPAAQEP 476
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 388 GPAPSPAPEQPAPVQ----VEAAQPTPP--------EARPAPE----AAPHpqpdvQPAPQPAQGPQSLMDATMQQEQEQ 451
Cdd:PRK10263 477 LYQQPQPVEQQPVVEpepvVEETKPARPplyyfeevEEKRAREreqlAAWY-----QPIPEPVKEPEPIKSSLKAPSVAA 551
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 452 EQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPvaqEPHPAQPVGQFLPVDGG-QVPTTPHLA 523
Cdd:PRK10263 552 VPPVEAAAAVSPLASGVKKATLATGAAATVAAPVFSLANSGGP---RPQVKEGIGPQLPRPKRiRVPTRRELA 621
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
190-344 |
7.26e-08 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 56.80 E-value: 7.26e-08
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 190 VPVPEQQAAEPVGAAQALVTRVATEAVAATggTPADAGESGEPQEAPAPEAAHT-----DAGWPVDPAEEAVPVPEAVPA 264
Cdd:PRK07994 367 EPEVPPQSAAPAASAQATAAPTAAVAPPQA--PAVPPPPASAPQQAPAVPLPETtsqllAARQQLQRAQGATKAKKSEPA 444
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 265 VPVA--PTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAevPAQAPQGLDEprvaDDAPEAPAPQEA 342
Cdd:PRK07994 445 AASRarPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVAT--PKALKKALEH----EKTPELAAKLAA 518
|
..
gi 7106671 343 PS 344
Cdd:PRK07994 519 EA 520
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
228-497 |
1.29e-07 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 56.20 E-value: 1.29e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 228 ESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAG---PEEALAVPEAQEV----- 299
Cdd:PRK10811 732 EQSVAEEAVAPVVEETVAAEPVVQEVPAPRTELVKVPLPVVAQTAPEQDEENNAENRDNngmPRRSRRSPRHLRVsgqrr 811
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 300 --------PAQSA---------PEEAPAEV----P-AEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPgdarA 357
Cdd:PRK10811 812 rryrderyPTQSPmpltvacasPEMASGKVwiryPvVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAP----V 887
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 358 VDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVqVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQ-- 435
Cdd:PRK10811 888 VEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQPQVI-TESDVAVAQEVAEHAEPVVEPQDETADIEEAAEta 966
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 436 -------GPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQ 497
Cdd:PRK10811 967 evvvaepEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQVPEATVEHNHATAPMTRAPAPEYVPEAPRH 1035
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
228-432 |
1.62e-07 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 55.55 E-value: 1.62e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 228 ESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTA----PVTEPVQATAEDDAGPEEALAVPEAQEVPAQS 303
Cdd:NF033839 282 DTPKEPGNKKPSAPKPGMQPSPQPEKKEVKPEPETPKPEVKPQLekpkPEVKPQPEKPKPEVKPQLETPKPEVKPQPEKP 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 304 APEEAPaEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTpgdaraVDAPVAAAEPEASAPEAAAPEPSVPE 383
Cdd:NF033839 362 KPEVKP-QPEKPKPEVKPQPETPKPEVKPQPEKPKPEVKPQPEKPKPE------VKPQPEKPKPEVKPQPEKPKPEVKPQ 434
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|
gi 7106671 384 AAEPGPAPSPAPEQPAPvQVEAAQPTP-PEARPAPEAaphPQPDVQPAPQ 432
Cdd:NF033839 435 PEKPKPEVKPQPEKPKP-EVKPQPETPkPEVKPQPEK---PKPEVKPQPE 480
|
|
| PHA03269 |
PHA03269 |
envelope glycoprotein C; Provisional |
91-200 |
1.70e-07 |
|
envelope glycoprotein C; Provisional
Pssm-ID: 165527 [Multi-domain] Cd Length: 566 Bit Score: 55.50 E-value: 1.70e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 91 RLPDPA----QDSATAPVPARRPLHLGPPIPDTSASPVrSLADRGPADAPVRHPGPPTAcPEYLDVPQ-AAVPTPQAAAP 165
Cdd:PHA03269 38 QKPDPApaphQAASRAPDPAVAPTSAASRKPDLAQAPT-PAASEKFDPAPAPHQAASRA-PDPAVAPQlAAAPKPDAAEA 115
|
90 100 110
....*....|....*....|....*....|....*.
gi 7106671 166 WgaQTAPQAQEVPVNAGAGHA-ETVVPVPEQQAAEP 200
Cdd:PHA03269 116 F--TSAAQAHEAPADAGTSAAsKKPDPAAHTQHSPP 149
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
235-410 |
2.08e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 55.26 E-value: 2.08e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 235 APAPEAAHTDAGWPVDPAEEAVPVPEAVPAVP---VAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAE 311
Cdd:PRK07994 363 APLPEPEVPPQSAAPAASAQATAAPTAAVAPPqapAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKKSE 442
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 312 vPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSlaPEPTPGDARAVdapvaaaepeasaPEAAAPEPSVPEAAEPGPAP 391
Cdd:PRK07994 443 -PAAASRARPVNSALERLASVRPAPSALEKAPAK--KEAYRWKATNP-------------VEVKKEPVATPKALKKALEH 506
|
170
....*....|....*....
gi 7106671 392 SPAPEQPAPVQVEAAQPTP 410
Cdd:PRK07994 507 EKTPELAAKLAAEAIERDP 525
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
139-350 |
4.56e-07 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 54.33 E-value: 4.56e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 139 HPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPvnaGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAA 218
Cdd:PRK08691 359 APLAAASCDANAVIENTELQSPSAQTAEKETAAKKPQPRP---EAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPP 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 219 TGGTPADAGESGEPqeAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTA--PVTEPVQATAEDDAGPEEALAVPEA 296
Cdd:PRK08691 436 WEDAPDEAQTAAGT--AQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSevPSENPIQATPNDEAVETETFAHEAP 513
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 297 QE------VPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEP 350
Cdd:PRK08691 514 AEpfygygFPDNDCPPEDGAEIPPPDWEHAAPADTAGGGADEEAEAGGIGGNNTPSAPPP 573
|
|
| PRK07003 |
PRK07003 |
DNA polymerase III subunit gamma/tau; |
9-287 |
8.14e-07 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 235906 [Multi-domain] Cd Length: 830 Bit Score: 53.70 E-value: 8.14e-07
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 9 GEGLPENAGMVEQPG-VPAPGAYTylsEATAEDEDLLLLPGAQSAWGNEVAPPAPEPVVETVHQPGPHEMSGRDSGSVDL 87
Cdd:PRK07003 364 GGGAPGGGVPARVAGaVPAPGARA---AAAVGASAVPAVTAVTGAAGAALAPKAAAAAAATRAEAPPAAPAPPATADRGD 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 88 GGVRLPDPAQDSATAPVPARRPLHLGPPIPDTSASPVRSLADRGPADAPvRHPGPPTACPEYLDVPQAAVPTPQAAAPWG 167
Cdd:PRK07003 441 DAADGDAPVPAKANARASADSRCDERDAQPPADSGSASAPASDAPPDAA-FEPAPRAAAPSAATPAAVPDARAPAAASRE 519
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 168 AQTAPQAQEVPVNAGAGhaetvvPVPEQQAAEPVGAAQAL-VTRVATEAVAATGGTPADAgesgepqeAPAPEAAHTDAG 246
Cdd:PRK07003 520 DAPAAAAPPAPEARPPT------PAAAAPAARAGGAAAALdVLRNAGMRVSSDRGARAAA--------AAKPAAAPAAAP 585
|
250 260 270 280
....*....|....*....|....*....|....*....|..
gi 7106671 247 WPVDP-AEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGP 287
Cdd:PRK07003 586 KPAAPrVAVQVPTPRARAATGDAPPNGAARAEQAAESRGAPP 627
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
382-536 |
1.24e-06 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 52.95 E-value: 1.24e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 382 PEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQ---PDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQE 458
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPasaPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 459 QEQEMAAvvvtdgTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDggqVPTTPHLAPTPPEAVLVPPET 536
Cdd:PRK07994 441 SEPAAAS------RARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVE---VKKEPVATPKALKKALEHEKT 509
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
218-355 |
1.37e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 52.41 E-value: 1.37e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 218 ATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAvpeaq 297
Cdd:PRK14951 367 AAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA----- 441
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 298 evPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPtPGDA 355
Cdd:PRK14951 442 --PAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE-EGDV 496
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
12-351 |
1.54e-06 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 53.02 E-value: 1.54e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 12 LPENAGMVEQPGVPAPGAYTYLSEATAEDEDLLLLPGAQSAWGNEVAP---PAPEPVVETVHQPGPHEMSGRDSGSvdlG 88
Cdd:PHA03247 2688 ARPTVGSLTSLADPPPPPPTPEPAPHALVSATPLPPGPAAARQASPALpaaPAPPAVPAGPATPGGPARPARPPTT---A 2764
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 89 GVRLPDPAQDSATAPVPARRPLHLGPPIPDTSASPvrslADRGPADAPVRHPGPPTACPEYlDVPQAAVPTPQAAAPWGA 168
Cdd:PHA03247 2765 GPPAPAPPAAPAAGPPRRLTRPAVASLSESRESLP----SPWDPADPPAAVLAPAAALPPA-ASPAGPLPPPTSAQPTAP 2839
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 169 QTAPQAQEVPVNAGAGHAE----TVVPVPEQQAAEPVGAAQALVTRVATEAVAATggTPADAGESGEPQEAPAPEAAHTD 244
Cdd:PHA03247 2840 PPPPGPPPPSLPLGGSVAPggdvRRRPPSRSPAAKPAAPARPPVRRLARPAVSRS--TESFALPPDQPERPPQPQAPPPP 2917
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 245 AGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALA--VPEAQEVPAQSAPEEAPAEVPAEVPAQAPQ 322
Cdd:PHA03247 2918 QPQPQPPPPPQPQPPPPPPPRPQPPLAPTTDPAGAGEPSGAVPQPWLGalVPGRVAVPRFRVPQPAPSREAPASSTPPLT 2997
|
330 340 350 360 370 380
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7106671 323 GLDEPRVA--------------------------DDAPEAPAPQ-----------EAPSSLAPEPT 351
Cdd:PHA03247 2998 GHSLSRVSswasslalheetdpppvslkqtlwppDDTEDSDADSlfdsdsersdlEALDPLPPEPH 3063
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
294-444 |
1.67e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 52.41 E-value: 1.67e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 294 PEAQEVPAQSAPEEAPAEVPAEVPAQAPQGldeprvadDAPEAPAPQEAPSSLAPEPTPGDARAVdapvaaaepeasape 373
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVA--------QAAAAPAPAAAPAAAASAPAAPPAAAP--------------- 422
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106671 374 aaAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDAT 444
Cdd:PRK14951 423 --PAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPT 491
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
55-444 |
2.42e-06 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 52.10 E-value: 2.42e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 55 NEVAPPAPEPVVETVHQPGPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLGPPIPDTSASPVRSLADRGPAD 134
Cdd:PHA03307 40 QGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAREGSPTPPGPSSPDPPPP 119
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 135 APVRHPGPPTacpeyldvpqaAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETvvpvpeqqAAEPVGAAQALVTRVATE 214
Cdd:PHA03307 120 TPPPASPPPS-----------PAPDLSEMLRPVGSPGPPPAASPPAAGASPAAV--------ASDAASSRQAALPLSSPE 180
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 215 AVAATGGTPAdAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQAtAEDDAGPEEALAVP 294
Cdd:PHA03307 181 ETARAPSSPP-AEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSES-SGCGWGPENECPLP 258
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 295 EAQEVPAQSAPEEAPAEVPAEVPAQAPqgldEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEA 374
Cdd:PHA03307 259 RPAPITLPTRIWEASGWNGPSSRPGPA----SSSSSPRERSPSPSPSSPGSGPAPSSPRASSSSSSSRESSSSSTSSSSE 334
|
330 340 350 360 370 380 390
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 375 AAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDAT 444
Cdd:PHA03307 335 SSRGAAVSPGPSPSRSPSPSRPPPPADPSSPRKRPRPSRAPSSPAASAGRPTRRRARAAVAGRARRRDAT 404
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
261-391 |
3.12e-06 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 51.25 E-value: 3.12e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 261 AVPAVPVAPTAPVTEPVQATAEddagpeeALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQ 340
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPA-------AAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAA 441
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 7106671 341 EAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAP 391
Cdd:PRK14951 442 PAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| Atrophin-1 |
pfam03154 |
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian ... |
22-434 |
4.21e-06 |
|
Atrophin-1 family; Atrophin-1 is the protein product of the dentatorubral-pallidoluysian atrophy (DRPLA) gene. DRPLA OMIM:125370 is a progressive neurodegenerative disorder. It is caused by the expansion of a CAG repeat in the DRPLA gene on chromosome 12p. This results in an extended polyglutamine region in atrophin-1, that is thought to confer toxicity to the protein, possibly through altering its interactions with other proteins. The expansion of a CAG repeat is also the underlying defect in six other neurodegenerative disorders, including Huntington's disease. One interaction of expanded polyglutamine repeats that is thought to be pathogenic is that with the short glutamine repeat in the transcriptional coactivator CREB binding protein, CBP. This interaction draws CBP away from its usual nuclear location to the expanded polyglutamine repeat protein aggregates that are characteriztic of the polyglutamine neurodegenerative disorders. This interferes with CBP-mediated transcription and causes cytotoxicity.
Pssm-ID: 460830 [Multi-domain] Cd Length: 991 Bit Score: 51.31 E-value: 4.21e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 22 PGVPAPGAYTYLSEATAEDEDLLLLPGA-QSAWGNEVAPPAPEPVVETVHQPGPhemsgrdsgsvdlggvrlPDPAQDSA 100
Cdd:pfam03154 146 PSIPSPQDNESDSDSSAQQQILQTQPPVlQAQSGAASPPSPPPPGTTQAATAGP------------------TPSAPSVP 207
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 101 TAPVPARRPlhlgPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVN 180
Cdd:pfam03154 208 PQGSPATSQ----PPNQTQSTAAPHTLIQQTPTLHPQRLPSPHPPLQPMTQPPPPSQVSPQPLPQPSLHGQMPPMPHSLQ 283
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 181 AGAGHAETvvPVPEQQAAEPVGAAQALVtrvateavaATGGTPADAGESGEPQEAPAPEAAhtdAGWPVDPAEEAV-PVP 259
Cdd:pfam03154 284 TGPSHMQH--PVPPQPFPLTPQSSQSQV---------PPGPSPAAPGQSQQRIHTPPSQSQ---LQSQQPPREQPLpPAP 349
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 260 EAVPAVPVAPTAPVTE---------------PVQATAEDDAGPEEALA---------VPEAQEVPAQSAPEEAPAEVPAE 315
Cdd:pfam03154 350 LSMPHIKPPPTTPIPQlpnpqshkhpphlsgPSPFQMNSNLPPPPALKplsslsthhPPSAHPPPLQLMPQSQQLPPPPA 429
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 316 VPAQAPQGLDEPRVADDAPEAPAPQEAPSSlAPEPT----PGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAE-PGPA 390
Cdd:pfam03154 430 QPPVLTQSQSLPPPAASHPPTSGLHQVPSQ-SPFPQhpfvPGGPPPITPPSGPPTSTSSAMPGIQPPSSASVSSSgPVPA 508
|
410 420 430 440
....*....|....*....|....*....|....*....|....*
gi 7106671 391 PSPAPEQPAPVQVEAA-QPTPPEARPAPEAAPHPQPDVQPAPQPA 434
Cdd:pfam03154 509 AVSCPLPPVQIKEEALdEAEEPESPPPPPRSPSPEPTVVNTPSHA 553
|
|
| PspC_subgroup_1 |
NF033838 |
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, ... |
194-438 |
4.66e-06 |
|
pneumococcal surface protein PspC, choline-binding form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A. The other form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site.
Pssm-ID: 468201 [Multi-domain] Cd Length: 684 Bit Score: 50.78 E-value: 4.66e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 194 EQQAAEPVGAAqaLVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWP-VDPAEEAVPVPEAVPAVPVAPTAP 272
Cdd:NF033838 234 EEEAKRRADAK--LKEAVEKNVATSEQDKPKRRAKRGVLGEPATPDKKENDAKSSdSSVGEETLPSPSLKPEKKVAEAEK 311
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 273 VTEPVQATAEDDAG------PEEALAVPEAQEVPAQSAPEEAPAEVpaeVPAQAPqgldEPRVADDAPEAPAPQEAPSSL 346
Cdd:NF033838 312 KVEEAKKKAKDQKEedrrnyPTNTYKTLELEIAESDVKVKEAELEL---VKEEAK----EPRNEEKIKQAKAKVESKKAE 384
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 347 AP--EPTPGDARAVDAPVAAAEPEASAPEAaapepsvPEAAEPGPAPSPAPEQPAPV-QVEAAQPTP----------PEA 413
Cdd:NF033838 385 ATrlEKIKTDRKKAEEEAKRKAAEEDKVKE-------KPAEQPQPAPAPQPEKPAPKpEKPAEQPKAekpadqqaeeDYA 457
|
250 260
....*....|....*....|....*
gi 7106671 414 RPAPEaAPHPQPDVQPaPQPAQGPQ 438
Cdd:NF033838 458 RRSEE-EYNRLTQQQP-PKTEKPAQ 480
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
216-441 |
5.79e-06 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 50.80 E-value: 5.79e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 216 VAATGGTPADAGESGEPQEAPAPEAAHTDAGwPVDPAEEAVPVPEAVP---------AVPVAPTAPVTEPVQATAEDDAG 286
Cdd:pfam09770 108 AARAAQSSAQPPASSLPQYQYASQQSQQPSK-PVRTGYEKYKEPEPIPdlqvdaslwGVAPKKAAAPAPAPQPAAQPASL 186
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 287 PEEALAVPEAQEVPAQ-----SAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVdap 361
Cdd:pfam09770 187 PAPSRKMMSLEEVEAAmraqaKKPAQQPAPAPAQPPAAPPAQQAQQQQQFPPQIQQQQQPQQQPQQPQQHPGQGHPV--- 263
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 362 vAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQP----------APVQVEAAQPTPPEARPAPEAAPHPQPDVQPAP 431
Cdd:pfam09770 264 -TILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPtqilqnpnrlSAARVGYPQNPQPGVQPAPAHQAHRQQGSFGRQ 342
|
250
....*....|.
gi 7106671 432 QPAQ-GPQSLM 441
Cdd:pfam09770 343 APIItHPQQLA 353
|
|
| PRK12373 |
PRK12373 |
NADH-quinone oxidoreductase subunit E; |
183-332 |
8.71e-06 |
|
NADH-quinone oxidoreductase subunit E;
Pssm-ID: 237082 [Multi-domain] Cd Length: 400 Bit Score: 49.42 E-value: 8.71e-06
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 183 AGHAETVVPVPE--QQAAEPVGAAQALVTrvaTEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGW-----PVDPAEEA 255
Cdd:PRK12373 171 AGKGPVVKPGPQigRYASEPAGGLTSLTE---EAGKARYNASKALAEDIGDTVKRIDGTEVPLLAPWqgdaaPVPPSEAA 247
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 256 VPVPEAVPAVPvAPTAPVTEPVQATAEDDAGPEEALAVPEAQE-VPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADD 332
Cdd:PRK12373 248 RPKSADAETNA-ALKTPATAPKAAAKNAKAPEAQPVSGTAAAEpAPKEAAKAAAAAAKPALEDKPRPLGIARPGGADD 324
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
263-438 |
1.19e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 49.48 E-value: 1.19e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 263 PAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRvaddaPEAPAPQEA 342
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAAR-----QQLQRAQGA 435
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 343 PSSLAPEPTPgdaravdapvaAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAP-----EQPAPVQVEAAQPTPPEARPAP 417
Cdd:PRK07994 436 TKAKKSEPAA-----------ASRARPVNSALERLASVRPAPSALEKAPAKKEayrwkATNPVEVKKEPVATPKALKKAL 504
|
170 180
....*....|....*....|.
gi 7106671 418 EAAPHPQPDVQPAPQPAQGPQ 438
Cdd:PRK07994 505 EHEKTPELAAKLAAEAIERDP 525
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
382-494 |
1.20e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 49.71 E-value: 1.20e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 382 PEAAEPGPAPSPAPEQ---PAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLmdatmqqEQEQEQEQEQE 458
Cdd:PRK14951 384 PEAAAPAAAPVAQAAAapaPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAV-------ALAPAPPAQAA 456
|
90 100 110
....*....|....*....|....*....|....*.
gi 7106671 459 QEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAP 494
Cdd:PRK14951 457 PETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PRK10765 |
PRK10765 |
oxygen-insensitive NADPH nitroreductase; |
650-851 |
1.52e-05 |
|
oxygen-insensitive NADPH nitroreductase;
Pssm-ID: 182710 Cd Length: 240 Bit Score: 47.66 E-value: 1.52e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 650 VLKVMRERRDIRnGFRSDPIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELATRQrdAYAKSlpkgrAKQ 729
Cdd:PRK10765 4 TIELILSHRSIR-HFTDEPISEAQREAIINAARAASSSSFLQCSSIIRITDKALREALVELTGGQ--KYVAQ-----AAE 75
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 730 FkelkieaildtpvnIVVTADptrggrhtLGRHTQ--PQ----------MAPYSSALAVENLWLAAraEGLGVGWVSFFD 797
Cdd:PRK10765 76 F--------------WVFCAD--------FNRHLQicPDaqlglaeqllIGAVDTAIMAQNALLAA--ESLGLGGVYIGG 131
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 798 ER----EMVRALGLPEHLDVVAYLCVGYVDefpDEPELmqagwSKRRPLSWVVHEETY 851
Cdd:PRK10765 132 LRnnieAVTELLKLPQHVLPLFGLCLGWPA---QNPDL-----KPRLPASLLVHENQY 181
|
|
| PRK07764 |
PRK07764 |
DNA polymerase III subunits gamma and tau; Validated |
71-299 |
1.63e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236090 [Multi-domain] Cd Length: 824 Bit Score: 49.21 E-value: 1.63e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 71 QPGPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPlhlGPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYL 150
Cdd:PRK07764 587 VVGPAPGAAGGEGPPAPASSGPPEEAARPAAPAAPAAPA---APAPAGAAAAPAEASAAPAPGVAAPEHHPKHVAVPDAS 663
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 151 DVPQ-----AAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQalvtrvateavAATGGTPAD 225
Cdd:PRK07764 664 DGGDgwpakAGGAAPAAPPPAPAPAAPAAPAGAAPAQPAPAPAATPPAGQADDPAAQPPQ-----------AAQGASAPS 732
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7106671 226 AGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVqaTAEDDAGPEEALAVPEAQEV 299
Cdd:PRK07764 733 PAADDPVPLPPEPDDPPDPAGAPAQPPPPPAPAPAAAPAAAPPPSPPSEEEE--MAEDDAPSMDDEDRRDAEEV 804
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
125-293 |
1.77e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 49.09 E-value: 1.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 125 RSLADRgPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPvPEQQAAEPVGAA 204
Cdd:PRK07994 355 RMLAFH-PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTS-QLLAARQQLQRA 432
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 205 QALVTRVATEAVAATGGTPAD------AGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVP-AVPVAPTAPVT-EP 276
Cdd:PRK07994 433 QGATKAKKSEPAAASRARPVNsalerlASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPkALKKALEHEKTpEL 512
|
170
....*....|....*..
gi 7106671 277 VQATAEDDAGPEEALAV 293
Cdd:PRK07994 513 AAKLAAEAIERDPWAAL 529
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
143-285 |
1.96e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 48.94 E-value: 1.96e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 143 PTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRvateavaatggt 222
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAA------------ 433
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 223 PADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDA 285
Cdd:PRK14951 434 PAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTEEGDV 496
|
|
| Herpes_BLLF1 |
pfam05109 |
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 ... |
49-323 |
2.50e-05 |
|
Herpes virus major outer envelope glycoprotein (BLLF1); This family consists of the BLLF1 viral late glycoprotein, also termed gp350/220. It is the most abundantly expressed glycoprotein in the viral envelope of the Herpesviruses and is the major antigen responsible for stimulating the production of neutralising antibodies in vivo.
Pssm-ID: 282904 [Multi-domain] Cd Length: 886 Bit Score: 48.76 E-value: 2.50e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 49 AQSAWGNEVAPPAPEPVVETVHQPGPHEMSGRDSGSVDLGGVRLPDPAqdsATAPVPARRPLHLGPPIPDTS-ASPVRSL 127
Cdd:pfam05109 479 AGTTSGASPVTPSPSPRDNGTESKAPDMTSPTSAVTTPTPNATSPTPA---VTTPTPNATSPTLGKTSPTSAvTTPTPNA 555
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 128 ADRGPAdapVRHPGPPTACPEYLDV-PQAAV--PTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAA 204
Cdd:pfam05109 556 TSPTPA---VTTPTPNATIPTLGKTsPTSAVttPTPNATSPTVGETSPQANTTNHTLGGTSSTPVVTSPPKNATSAVTTG 632
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 205 QALVTRVATEAVAAtggTPADAGESGEPQEA-------PAPEAAHTDAGWPVDPAeeavpVPEAVPAVPVAPTAPVTEPv 277
Cdd:pfam05109 633 QHNITSSSTSSMSL---RPSSISETLSPSTSdnstshmPLLTSAHPTGGENITQV-----TPASTSTHHVSTSSPAPRP- 703
|
250 260 270 280 290
....*....|....*....|....*....|....*....|....*....|...
gi 7106671 278 qATAEDDAGPEEALAVPEAQEV-------PAQSAPEEAPAEVPAEVPAQAPQG 323
Cdd:pfam05109 704 -GTTSQASGPGNSSTSTKPGEVnvtkgtpPKNATSPQAPSGQKTAVPTVTSTG 755
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
346-536 |
4.10e-05 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 47.95 E-value: 4.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 346 LAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQP 425
Cdd:PRK12323 361 LAFRPGQSGGGAGPATAAAAPVAQPAPAAAAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQAS 440
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 426 DVQPAPQPAQGPqslmdATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEP-------APVPAPVAQE 498
Cdd:PRK12323 441 ARGPGGAPAPAP-----APAAAPAAAARPAAAGPRPVAAAAAAAPARAAPAAAPAPADDDPPPweelppeFASPAPAQPD 515
|
170 180 190
....*....|....*....|....*....|....*...
gi 7106671 499 PHPAQPVGQFLPVDGGQVPTTPHLAPTPPEAVLVPPET 536
Cdd:PRK12323 516 AAPAGWVAESIPDPATADPDDAFETLAPAPAAAPAPRA 553
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
248-527 |
4.25e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 48.24 E-value: 4.25e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 248 PVDPAEEAVPVP-EAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDE 326
Cdd:PHA03307 24 PPATPGDAADDLlSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPARE 103
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 327 PRVADDAPEAPAPQEAPSSLA--PEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVE 404
Cdd:PHA03307 104 GSPTPPGPSSPDPPPPTPPPAspPPSPAPDLSEMLRPVGSPGPPPAASPPAAGASPAAVASDAASSRQAALPLSSPEETA 183
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 405 AAQPTPPEARP----APEAAPHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADA 480
Cdd:PHA03307 184 RAPSSPPAEPPpstpPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPI 263
|
250 260 270 280
....*....|....*....|....*....|....*....|....*..
gi 7106671 481 PATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDGGQVPTTPHLAPTPP 527
Cdd:PHA03307 264 TLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPS 310
|
|
| PHA03377 |
PHA03377 |
EBNA-3C; Provisional |
21-445 |
5.10e-05 |
|
EBNA-3C; Provisional
Pssm-ID: 177614 [Multi-domain] Cd Length: 1000 Bit Score: 47.74 E-value: 5.10e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 21 QPGVPAPGAYTYLSEATAEDEDLLLLPGAQSAWGNEVAPPAPEPVVET---VHQPGPH----------EMSGRDSGS--- 84
Cdd:PHA03377 427 HPVKRTLVKTSGRSDEAEQAQSTPERPGPSDQPSVPVEPAHLTPVEHTtviLHQPPQSpptvaikpapPPSRRRRGAcvv 506
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 85 -----VDLGGVRLPDPAQDSATAPVPARRPLHLGP---PIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAA 156
Cdd:PHA03377 507 ydddiIEVIDVETTEEEESVTQPAKPHRKVQDGFQrsgRRQKRATPPKVSPSDRGPPKASPPVMAPPSTGPRVMATPSTG 586
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 157 vptPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEavaATGGTPADAGESGEPQEAP 236
Cdd:PHA03377 587 ---PRDMAPPSTGPRQQAKCKDGPPASGPHEKQPPSSAPRDMAPSVVRMFLRERLLEQ---STGPKPKSFWEMRAGRDGS 660
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 237 A----PEAAHTDAGWPVDPAEEAVPVPEAVPAV--------------PVAPTAPVTEPVQATAEDDAGPEEALAVPEAQE 298
Cdd:PHA03377 661 GiqqePSSRRQPATQSTPPRPSWLPSVFVLPSVdagraqpseeshlsSMSPTQPISHEEQPRYEDPDDPLDLSLHPDQAP 740
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 299 VPAQSAPEEAPAEVPAEvpaQAP-QGLDEPRvaddapeapaPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAP 377
Cdd:PHA03377 741 PPSHQAPYSGHEEPQAQ---QAPyPGYWEPR----------PPQAPYLGYQEPQAQGVQVSSYPGYAGPWGLRAQHPRYR 807
|
410 420 430 440 450 460 470
....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 378 EPSVPEAAEPGPAPSPAPEQPAPVQVEAA-QPTPPEARPAPEAAPHPQPD-VQPAPQPAQGPQSLMDATM 445
Cdd:PHA03377 808 HSWAYWSQYPGHGHPQGPWAPRPPHLPPQwDGSAGHGQDQVSQFPHLQSEtGPPRLQLSQVPQLPYSQTL 877
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
95-214 |
6.75e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 47.02 E-value: 6.75e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 95 PAQDSATAPVPARRPlhlgPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQA 174
Cdd:PRK14951 381 PARPEAAAPAAAPVA----QAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPPAQAA 456
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 7106671 175 QEVPvnagAGHAETVVPVPEQQAAEPVGAAQALVTRVATE 214
Cdd:PRK14951 457 PETV----AIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
130-504 |
6.77e-05 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 47.47 E-value: 6.77e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 130 RGPADAPVRHPGPPTACPEYLDVPQA-AVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALV 208
Cdd:PHA03307 23 RPPATPGDAADDLLSGSQGQLVSDSAeLAAVTVVAGAAACDRFEPPTGPPPGPGTEAPANESRSTPTWSLSTLAPASPAR 102
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 209 TRVATEAVAATGGTPADAGESGEPQEAPAPeaahtdagwpvdpaeeavPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPE 288
Cdd:PHA03307 103 EGSPTPPGPSSPDPPPPTPPPASPPPSPAP------------------DLSEMLRPVGSPGPPPAASPPAAGASPAAVAS 164
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 289 EALAVPEAQeVPAQSAPEEAPAEVPaevPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPE 368
Cdd:PHA03307 165 DAASSRQAA-LPLSSPEETARAPSS---PPAEPPPSTPPAAASPRPPRRSSPISASASSPAPAPGRSAADDAGASSSDSS 240
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 369 ASAPEAAAPEPSvpeaaEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQQE 448
Cdd:PHA03307 241 SSESSGCGWGPE-----NECPLPRPAPITLPTRIWEASGWNGPSSRPGPASSSSSPRERSPSPSPSSPGSGPAPSSPRAS 315
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 449 QEQEQEQEQEQEQEMAAVVVTDGTA---GPVAADAPATGAQEPAPVPAPVAQEPHPAQP 504
Cdd:PHA03307 316 SSSSSSRESSSSSTSSSSESSRGAAvspGPSPSRSPSPSRPPPPADPSSPRKRPRPSRA 374
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
171-352 |
6.84e-05 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 46.90 E-value: 6.84e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 171 APQAQEVPvnaGAGHAETVVpvpEQQAAEPVGAAQALVTRVATEAVAAtggtPADAGESGEPQEAPAPEAAHTDAGWPVD 250
Cdd:PRK13108 275 APKGREAP---GALRGSEYV---VDEALEREPAELAAAAVASAASAVG----PVGPGEPNQPDDVAEAVKAEVAEVTDEV 344
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 251 PAEEAVPVPEAVPAVPVAPTApVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQgldEPRVA 330
Cdd:PRK13108 345 AAESVVQVADRDGESTPAVEE-TSEADIEREQPGDLAGQAPAAHQVDAEAASAAPEEPAALASEAHDETEPE---VPEKA 420
|
170 180
....*....|....*....|..
gi 7106671 331 DDAPEAPAPQEaPSSLAPEPTP 352
Cdd:PRK13108 421 APIPDPAKPDE-LAVAGPGDDP 441
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
343-496 |
8.15e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 46.78 E-value: 8.15e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 343 PSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPH 422
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTSQLLAARQQLQRAQGATKAKK 440
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 7106671 423 PQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVA 496
Cdd:PRK07994 441 SEPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAA 514
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
210-418 |
8.49e-05 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 46.74 E-value: 8.49e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 210 RVATEAVAATGGTPADageSGEPQEAPAPEAAHT-DAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQA--------- 279
Cdd:PRK14086 83 RIAITVDPSAGEPAPP---PPHARRTSEPELPRPgRRPYEGYGGPRADDRPPGLPRQDQLPTARPAYPAYQqrpepgawp 159
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 280 TAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPA-PQEAPSSLAPEPTPGDARAV 358
Cdd:PRK14086 160 RAADDYGWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWdRPRRDRTDRPEPPPGAGHVH 239
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 359 DAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPApeqpapvqveaaqptPPEARPAPE 418
Cdd:PRK14086 240 RGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPG---------------EPTARLNPK 284
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
178-357 |
8.51e-05 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 47.01 E-value: 8.51e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 178 PVNAGAGHAETVVP-----VPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWP---- 248
Cdd:PRK08691 360 PLAAASCDANAVIEntelqSPSAQTAEKETAAKKPQPRPEAETAQTPVQTASAAAMPSEGKTAGPVSNQENNDVPPweda 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 249 VDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEA--QEVPAQSAPEEAPAEVPA---EVPAQA--- 320
Cdd:PRK08691 440 PDEAQTAAGTAQTSAKSIQTASEAETPPENQVSKNKAADNETDAPLSEvpSENPIQATPNDEAVETETfahEAPAEPfyg 519
|
170 180 190 200
....*....|....*....|....*....|....*....|
gi 7106671 321 ---PQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARA 357
Cdd:PRK08691 520 ygfPDNDCPPEDGAEIPPPDWEHAAPADTAGGGADEEAEA 559
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
245-357 |
8.64e-05 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 46.63 E-value: 8.64e-05
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 245 AGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPqgl 324
Cdd:PRK14951 370 AEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVA--- 446
|
90 100 110
....*....|....*....|....*....|...
gi 7106671 325 dePRVADDAPEAPAPQEAPSSLAPEPTPGDARA 357
Cdd:PRK14951 447 --LAPAPPAQAAPETVAIPVRVAPEPAVASAAP 477
|
|
| PAT1 |
pfam09770 |
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate ... |
382-527 |
1.55e-04 |
|
Topoisomerase II-associated protein PAT1; Members of this family are necessary for accurate chromosome transmission during cell division.
Pssm-ID: 401645 [Multi-domain] Cd Length: 846 Bit Score: 46.18 E-value: 1.55e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 382 PEAAEPGPAPSPAPEQPAPV--------QVEA---AQPTPPEARPAPEAAPHPQ-PDVQPAPQPAQGPQSLMDATMQQEQ 449
Cdd:pfam09770 170 AAAPAPAPQPAAQPASLPAPsrkmmsleEVEAamrAQAKKPAQQPAPAPAQPPAaPPAQQAQQQQQFPPQIQQQQQPQQQ 249
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 450 EQEQEQEQEQEQEMAavVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQ----PVGQFLPVDGGQVPTTPHLAPT 525
Cdd:pfam09770 250 PQQPQQHPGQGHPVT--ILQRPQSPQPDPAQPSIQPQAQQFHQQPPPVPVQPTQilqnPNRLSAARVGYPQNPQPGVQPA 327
|
..
gi 7106671 526 PP 527
Cdd:pfam09770 328 PA 329
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
254-359 |
1.89e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 45.57 E-value: 1.89e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 254 EAVPVPEAVPAvPVAPTAPVTEPVQATAeddaGPEEALAVPEAQEVPAQSA-PEEAPAEVPAEVPAQAPQGLDEPRVADD 332
Cdd:PRK14950 357 EALLVPVPAPQ-PAKPTAAAPSPVRPTP----APSTRPKAAAAANIPPKEPvRETATPPPVPPRPVAPPVPHTPESAPKL 431
|
90 100
....*....|....*....|....*..
gi 7106671 333 APEAPAPQEAPSSLAPEPTPGDARAVD 359
Cdd:PRK14950 432 TRAAIPVDEKPKYTPPAPPKEEEKALI 458
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
132-438 |
2.20e-04 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 45.85 E-value: 2.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 132 PADAPVRHPGPPTACPEYLDVPQAAV-PTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALvtr 210
Cdd:PRK10263 315 PITEPVAVAAAATTATQSWAAPVEPVtQTPPVASVDVPPAQPTVAWQPVPGPQTGEPVIAPAPEGYPQQSQYAQPAV--- 391
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 211 vateavaatggtpadagESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEA 290
Cdd:PRK10263 392 -----------------QYNEPLQQPVQPQQPYYAPAAEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQQS 454
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 291 LAVPEAQEVPAQSAPEeapaEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEAS 370
Cdd:PRK10263 455 TFAPQSTYQTEQTYQQ----PAAQEPLYQQPQPVEQQPVVEPEPVVEETKPARPPLYYFEEVEEKRAREREQLAAWYQPI 530
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 371 APEAAAPEPSVPEAAEPGPAPSPAPEQP---APVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQP----AQGPQ 438
Cdd:PRK10263 531 PEPVKEPEPIKSSLKAPSVAAVPPVEAAaavSPLASGVKKATLATGAAATVAAPVFSLANSGGPRPqvkeGIGPQ 605
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
120-256 |
2.35e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 45.48 E-value: 2.35e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 120 SASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAE 199
Cdd:PRK14951 373 AAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAAPPAPVAAPAAAAPAAAPAAAPAAVALAPAPP 452
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 200 PVGAAQALVTRVATEA-VAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAV 256
Cdd:PRK14951 453 AQAAPETVAIPVRVAPePAVASAAPAPAAAPAAARLTPTEEGDVWHATVQQLAAAEAI 510
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
43-354 |
3.20e-04 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 45.05 E-value: 3.20e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 43 LLLLPGAQSAWGNEVAPPAPEPVVET----VHQPGPhEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLGP-PIP 117
Cdd:PHA03379 390 LLMRAGKLTERAREALEKASEPTYGTprppVEKPRP-EVPQSLETATSHGSAQVPEPPPVHDLEPGPLHDQHSMAPcPVA 468
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 118 DTSASPVRSLAdrgPADapvRHPGPPTacpeylDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAghaeTVVPVPEQQA 197
Cdd:PHA03379 469 QLPPGPLQDLE---PGD---QLPGVVQ------DGRPACAPVPAPAGPIVRPWEASLSQVPGVAFA----PVMPQPMPVE 532
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 198 AEPVGA-AQALVTRVATEAVAATGgtPADAGESGEPQEAPAPeaahtdAGWPVDPAEEAVPVP-----EAVPAVPVAPTA 271
Cdd:PHA03379 533 PVPVPTvALERPVCPAPPLIAMQG--PGETSGIVRVRERWRP------APWTPNPPRSPSQMSvrdrlARLRAEAQPYQA 604
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 272 PV-TEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEP 350
Cdd:PHA03379 605 SVeVQPPQLTQVSPQQPMEYPLEPEQQMFPGSPFSQVADVMRAGGVPAMQPQYFDLPLQQPISQGAPLAPLRASMGPVPP 684
|
....
gi 7106671 351 TPGD 354
Cdd:PHA03379 685 VPAT 688
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
182-352 |
3.38e-04 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 44.58 E-value: 3.38e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 182 GAGHAETVVPVPEQQAAEPVGAAQAlvtrvatEAVAATGGTPADAGESGEPQEAPAPEAAHTDAgwpvdPAEEAVPVPEA 261
Cdd:PHA03169 94 GSGSESVGSPTPSPSGSAEELASGL-------SPENTSGSSPESPASHSPPPSPPSHPGPHEPA-----PPESHNPSPNQ 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 262 VPAVPVAPTAPvTEPVQATAEDDAGPEEALAVPEAQEvPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQE 341
Cdd:PHA03169 162 QPSSFLQPSHE-DSPEEPEPPTSEPEPDSPGPPQSET-PTSSPPPQSPPDEPGEPQSPTPQQAPSPNTQQAVEHEDEPTE 239
|
170
....*....|.
gi 7106671 342 APSSLAPEPTP 352
Cdd:PHA03169 240 PEREGPPFPGH 250
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
382-439 |
3.41e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.88 E-value: 3.41e-04
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 382 PEAAEPGPAPSPAPEQPAPVQ-VEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPaAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAP 96
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
393-536 |
3.75e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 44.71 E-value: 3.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 393 PAPEQPAPVQVEAAQPTPPEArPAPEAAPHPQPDVQPAPQPAQgpqslmdatmqqeqeqeqeqeqeqEQEMAAVVVTDGT 472
Cdd:PRK14951 366 PAAAAEAAAPAEKKTPARPEA-AAPAAAPVAQAAAAPAPAAAP------------------------AAAASAPAAPPAA 420
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7106671 473 AGPVAADAPATGAQEPAP--VPAPVAQEPHPAQPVGQFLPVDGGQVPTTPHLAPTPPEAVLVPPET 536
Cdd:PRK14951 421 APPAPVAAPAAAAPAAAPaaAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
355-502 |
4.23e-04 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 44.47 E-value: 4.23e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 355 ARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPP-----EARPAPEAAPHPQPDVQP 429
Cdd:PRK07994 362 AAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETtsqllAARQQLQRAQGATKAKKS 441
|
90 100 110 120 130 140 150
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 430 APQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATgaqEPAPVPAPVAQEPHPA 502
Cdd:PRK07994 442 EPAAASRARPVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVA---TPKALKKALEHEKTPE 511
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
340-438 |
4.74e-04 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 44.50 E-value: 4.74e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 340 QEAPSSLAPE-------PTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPE 412
Cdd:PRK12270 19 LADPNSVDPSwreffadYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAA 98
|
90 100
....*....|....*....|....*.
gi 7106671 413 ARPAPEAAPHPQPDVQPAPQPAQGPQ 438
Cdd:PRK12270 99 PPAAAAAAAPAAAAVEDEVTPLRGAA 124
|
|
| PRK12323 |
PRK12323 |
DNA polymerase III subunit gamma/tau; |
43-264 |
5.01e-04 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237057 [Multi-domain] Cd Length: 700 Bit Score: 44.48 E-value: 5.01e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 43 LLLLPGAQSAWGNEVAPPAPEPVVETVHQP-GPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLGPPIPDTSA 121
Cdd:PRK12323 360 MLAFRPGQSGGGAGPATAAAAPVAQPAPAAaAPAAAAPAPAAPPAAPAAAPAAAAAARAVAAAPARRSPAPEALAAARQA 439
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 122 SPVRSLADRGPADAPVRHPGP--PTACPEYLDVPQAAVPTPQAAAPwGAQTAPQAQEVPVNAGAGhAETVVPVPEQQAAE 199
Cdd:PRK12323 440 SARGPGGAPAPAPAPAAAPAAaaRPAAAGPRPVAAAAAAAPARAAP-AAAPAPADDDPPPWEELP-PEFASPAPAQPDAA 517
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 200 PVGAAQALVTRVATEAVAATGGTPAdagESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPA 264
Cdd:PRK12323 518 PAGWVAESIPDPATADPDDAFETLA---PAPAAAPAPRAAAATEPVVAPRPPRASASGLPDMFDG 579
|
|
| PRK14949 |
PRK14949 |
DNA polymerase III subunits gamma and tau; Provisional |
155-536 |
5.21e-04 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237863 [Multi-domain] Cd Length: 944 Bit Score: 44.33 E-value: 5.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 155 AAVPTPQAAAPwgaqTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADA-GESGEPQ 233
Cdd:PRK14949 372 AEISLPEGQTP----SALAAAVQAPHANEPQFVNAAPAEKKTALTEQTTAQQQVQAANAEAVAEADASAEPAdTVEQALD 447
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 234 EAPAPEAAHTD---------AGWPVDPAEEAVPVPEAVPAvpVAPTAPVTEPVQATAEDDagpeealAVPEAQEVPAQSA 304
Cdd:PRK14949 448 DESELLAALNAeqavilsqaQSQGFEASSSLDADNSAVPE--QIDSTAEQSVVNPSVTDT-------QVDDTSASNNSAA 518
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 305 PEEAPAEVPAEVPAQAPQGLDEPRVADDAPEApAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEA 384
Cdd:PRK14949 519 DNTVDDNYSAEDTLESNGLDEGDYAQDSAPLD-AYQDDYVAFSSESYNALSDDEQHSANVQSAQSAAEAQPSSQSLSPIS 597
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 385 AEPGPAPSPA------------------------PEQPAPVQVEAAQPTPPEARPAPeaAPHPQPDVQPAPQPAQGPQSL 440
Cdd:PRK14949 598 AVTTAAASLAdddildavlaardsllsdldalspKEGDGKKSSADRKPKTPPSRAPP--ASLSKPASSPDASQTSASFDL 675
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 441 MDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQFLPVDGGQVPTTP 520
Cdd:PRK14949 676 DPDFELATHQSVPEAALASGSAPAPPPVPDPYDRPPWEEAPEVASANDGPNNAAEGNLSESVEDASNSELQAVEQQATHQ 755
|
410
....*....|....*....
gi 7106671 521 HLAPT---PPEAVLVPPET 536
Cdd:PRK14949 756 PQVQAeaqSPASTTALTQT 774
|
|
| PHA03378 |
PHA03378 |
EBNA-3B; Provisional |
222-529 |
5.63e-04 |
|
EBNA-3B; Provisional
Pssm-ID: 223065 [Multi-domain] Cd Length: 991 Bit Score: 44.29 E-value: 5.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 222 TPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPV---PEAVPAVPVAP-----TAPVTEPVQATAEDDAGPEEALAV 293
Cdd:PHA03378 611 TQSHIPETSAPRQWPMPLRPIPMRPLRMQPITFNVLVfptPHQPPQVEITPykptwTQIGHIPYQPSPTGANTMLPIQWA 690
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 294 PEAQEVPAQsAPEEAPAEVPAEVPAQAPQGLDEPrvaddapeAPAPQEAPSSL-APEPTPGDARavdapvaaaepeasaP 372
Cdd:PHA03378 691 PGTMQPPPR-APTPMRPPAAPPGRAQRPAAATGR--------ARPPAAAPGRArPPAAAPGRAR---------------P 746
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 373 EAAAPEPSVPEAAEPGPAPSP--APEQPAPVQveaaqptPPEARPAPEAAPHPQPdvQPAPQPAQGPqslmdATMQQEQE 450
Cdd:PHA03378 747 PAAAPGRARPPAAAPGRARPPaaAPGAPTPQP-------PPQAPPAPQQRPRGAP--TPQPPPQAGP-----TSMQLMPR 812
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 451 QEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAP---------VAQEPHPAQPVGQFLPVDGGQVPTTPH 521
Cdd:PHA03378 813 AAPGQQGPTKQILRQLLTGGVKRGRPSLKKPAALERQAAAGPTPspgsgtsdkIVQAPVFYPPVLQPIQVMRQLGSVRAA 892
|
....*...
gi 7106671 522 LAPTPPEA 529
Cdd:PHA03378 893 AASTVTQA 900
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
90-285 |
6.75e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 44.05 E-value: 6.75e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 90 VRLPDPAQDSATAPVPARR--PLHLGPPIPDTSASPVRSLADRGPAD---APVRHPGPPTACPEYLDVPQAAVPTPQAAA 164
Cdd:PRK14086 82 IRIAITVDPSAGEPAPPPPhaRRTSEPELPRPGRRPYEGYGGPRADDrppGLPRQDQLPTARPAYPAYQQRPEPGAWPRA 161
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 165 PwgAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTD 244
Cdd:PRK14086 162 A--DDYGWQQQRLGFPPRAPYASPASYAPEQERDREPYDAGRPEYDQRRRDYDHPRPDWDRPRRDRTDRPEPPPGAGHVH 239
|
170 180 190 200
....*....|....*....|....*....|....*....|.
gi 7106671 245 AGWPVDPAEEAVPVPEAVPAVPVaPTAPVTEPVQATAEDDA 285
Cdd:PRK14086 240 RGGPGPPERDDAPVVPIRPSAPG-PLAAQPAPAPGPGEPTA 279
|
|
| dnaA |
PRK14086 |
chromosomal replication initiator protein DnaA; |
275-504 |
7.94e-04 |
|
chromosomal replication initiator protein DnaA;
Pssm-ID: 237605 [Multi-domain] Cd Length: 617 Bit Score: 43.66 E-value: 7.94e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 275 EPVQATAEDDAGPEEALAVP-EAQEVPAQSAPEEAPAEVPAEVPAQAPQGLD--EPRVADDAPEAPAPQeapsSLAPEPT 351
Cdd:PRK14086 68 PIISETLSRELGRPIRIAITvDPSAGEPAPPPPHARRTSEPELPRPGRRPYEgyGGPRADDRPPGLPRQ----DQLPTAR 143
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 352 PG-DARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQ------PAPVQVEAAQPTPPEARPAPEAAPhPQ 424
Cdd:PRK14086 144 PAyPAYQQRPEPGAWPRAADDYGWQQQRLGFPPRAPYASPASYAPEQerdrepYDAGRPEYDQRRRDYDHPRPDWDR-PR 222
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 425 PDVQPAPQPAQGpqslmdatmqqeqeqeqeqeqeqeqemAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQP 504
Cdd:PRK14086 223 RDRTDRPEPPPG---------------------------AGHVHRGGPGPPERDDAPVVPIRPSAPGPLAAQPAPAPGPG 275
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
211-330 |
8.17e-04 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 43.42 E-value: 8.17e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 211 VATEAVAATggtpADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEA 290
Cdd:PRK06995 43 LADSDLAAL----APPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAA 118
|
90 100 110 120
....*....|....*....|....*....|....*....|
gi 7106671 291 LAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVA 330
Cdd:PRK06995 119 PAERAAAENAARRLARAAAAAPRPRVPADAAAAVADAVKA 158
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
316-439 |
8.21e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.22 E-value: 8.21e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 316 VPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAP---EPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPS 392
Cdd:NF040712 196 LRPLATVPRLAREPADARPEEVEPAPAAEGAPAtdsDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATR 275
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|.
gi 7106671 393 PAPEQPAPVQ---VEAAQPTPPEAR-PAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:NF040712 276 DAGEPPAPGAaetPEAAEPPAPAPAaPAAPAAPEAEEPARPEPPPAPKPKR 326
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
218-351 |
8.57e-04 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 43.22 E-value: 8.57e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 218 ATGGTPADAGESGEPQE-APAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEA 296
Cdd:NF040712 200 ATVPRLAREPADARPEEvEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGE 279
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 297 QEVPAQsAPEEAPAEVPAEVPAqAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPT 351
Cdd:NF040712 280 PPAPGA-AETPEAAEPPAPAPA-APAAPAAPEAEEPARPEPPPAPKPKRRRRRAS 332
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
160-342 |
8.91e-04 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 43.70 E-value: 8.91e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 160 PQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGE----PQEA 235
Cdd:PLN03237 1246 AKKKAPAAAKEKEEEDEILDLKDRLAAYNLDSAPAQSAKMEETVKAVPARRAAARKKPLASVSVISDSDDDDddfaVEVS 1325
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 236 PAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAP----VTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAE 311
Cdd:PLN03237 1326 LAERLKKKGGRKPAAANKKAAKPPAAAKKRGPATVQSgqklLTEMLKPAEAIGISPEKKVRKMRASPFNKKSGSVLGRAA 1405
|
170 180 190
....*....|....*....|....*....|...
gi 7106671 312 VPAEVP--AQAPQGLDEPRVADDAPEAPAPQEA 342
Cdd:PLN03237 1406 TNKETEssENVSGSSSSEKDEIDVSAKPRPQRA 1438
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
199-435 |
9.19e-04 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 43.77 E-value: 9.19e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 199 EPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVP-----------VPEAVPAVPV 267
Cdd:PHA03247 235 EPFVERRVVISHPLRGDIAAPAPPPVVGEGADRAPETARGATGPPPPPEAAAPNGAAAPpdgvwgaalagAPLALPAPPD 314
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 268 APTAPVTEPVQATAEDDAGPEEALAVPEA-QEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVAD-------DAPEAPAP 339
Cdd:PHA03247 315 PPPPAPAGDAEEEDDEDGAMEVVSPLPRPrQHYPLGFPKRRRPTWTPPSSLEDLSAGRHHPKRASlptrkrrSARHAATP 394
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 340 QEAPSSLAPEPTPGDAR-AVDAPVAAAEPEASAPEAAAPEPSVPEAAEP-GPAPSPAPEQPAPVQVEAAQPTPPEARPAP 417
Cdd:PHA03247 395 FARGPGGDDQTRPAAPVpASVPTPAPTPVPASAPPPPATPLPSAEPGSDdGPAPPPERQPPAPATEPAPDDPDDATRKAL 474
|
250
....*....|....*...
gi 7106671 418 EAAPHPQPDVQPAPQPAQ 435
Cdd:PHA03247 475 DALRERRPPEPPGADLAE 492
|
|
| PspC_subgroup_2 |
NF033839 |
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, ... |
213-536 |
9.63e-04 |
|
pneumococcal surface protein PspC, LPXTG-anchored form; The pneumococcal surface protein PspC, as described in Streptococcus pneumoniae, is a repetitive and highly variable protein, recognized by a conserved N-terminal domain and also by genomic location. This form, subgroup 2, is anchored covalently after cleavage by sortase at a C-terminal LPXTG site. The other form, subgroup 1, has variable numbers of a choline-binding repeat in the C-terminal region, and is also known as choline-binding protein A.
Pssm-ID: 468202 [Multi-domain] Cd Length: 557 Bit Score: 43.22 E-value: 9.63e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 213 TEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAP--------TAPVTEPVQATAEDD 284
Cdd:NF033839 137 DEAVSKFEKDSSSSSSSGSSTKPETPQPENPEHQKPTTPAPDTKPSPQPEGKKPSVPdinqekekAKLAVATYMSKILDD 216
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 285 AGPEEALAVPEAQEVPAQSAPEEAPAEVPAEV----PAQAPQGLDEPRVADD-----------APEAPAPQEAPSSLAPE 349
Cdd:NF033839 217 IQKHHLQKEKHRQIVALIKELDELKKQALSEIdnvnTKVEIENTVHKIFADMdavvtkfkkglTQDTPKEPGNKKPSAPK 296
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 350 PtpgdarAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPvQVEAAQPTP-PEARPAPEAaphPQPDVQ 428
Cdd:NF033839 297 P------GMQPSPQPEKKEVKPEPETPKPEVKPQLEKPKPEVKPQPEKPKP-EVKPQLETPkPEVKPQPEK---PKPEVK 366
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 429 P---APQPAQGPQslmdatmqqEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQE--PHPAQ 503
Cdd:NF033839 367 PqpeKPKPEVKPQ---------PETPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEVKPQPEKPKPEvkPQPEK 437
|
330 340 350
....*....|....*....|....*....|...
gi 7106671 504 PVGQFLPVDGGQVPTTPHLAPTPPEAVLVPPET 536
Cdd:NF033839 438 PKPEVKPQPEKPKPEVKPQPETPKPEVKPQPEK 470
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
401-565 |
9.64e-04 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 43.49 E-value: 9.64e-04
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 401 VQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAADA 480
Cdd:PRK10811 848 VRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPVVEAVAEVVEEPVVVAEPQPEEVVVVETTHPEVIAAPVTEQ 927
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 481 PATGAQEPAPVPAPVAQEPHPAQPVgQFLPVDGGQVPTTPHLAPTPPEAVLVPPETAAEPEPVAAAPAAEEAVAPVPAPR 560
Cdd:PRK10811 928 PQVITESDVAVAQEVAEHAEPVVEP-QDETADIEEAAETAEVVVAEPEVVAQPAAPVVAEVAAEVETVTAVEPEVAPAQV 1006
|
....*
gi 7106671 561 EADPE 565
Cdd:PRK10811 1007 PEATV 1011
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
287-468 |
1.10e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 43.32 E-value: 1.10e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 287 PEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQgldeprVADDAPEAPAPQEAPSSLAPEPTPGDARAvdapvaaae 366
Cdd:PRK07994 361 PAAPLPEPEVPPQSAAPAASAQATAAPTAAVAPPQA------PAVPPPPASAPQQAPAVPLPETTSQLLAA--------- 425
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 367 peasapeaaAPEPSVPEAAEPGPAPSPAPEQPAPvQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQ 446
Cdd:PRK07994 426 ---------RQQLQRAQGATKAKKSEPAAASRAR-PVNSALERLASVRPAPSALEKAPAKKEAYRWKATNPVEVKKEPVA 495
|
170 180
....*....|....*....|..
gi 7106671 447 QEQEQEQEQEQEQEQEMAAVVV 468
Cdd:PRK07994 496 TPKALKKALEHEKTPELAAKLA 517
|
|
| PRK12678 |
PRK12678 |
transcription termination factor Rho; Provisional |
268-436 |
1.22e-03 |
|
transcription termination factor Rho; Provisional
Pssm-ID: 237171 [Multi-domain] Cd Length: 672 Bit Score: 42.97 E-value: 1.22e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 268 APTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQ---------------SAPEEA--PAEVPAEVPAQAPQGLDEPRVA 330
Cdd:PRK12678 3 PSDAAATATTDTAPRARGGGLAGMKLPELRALAKQlgikgtsgmrkgeliAAIKEArgGGAAAAAATPAAPAAAARRAAR 82
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 331 DDAPEAPAPQEAPsslAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTP 410
Cdd:PRK12678 83 AAAAARQAEQPAA---EAAAAKAEAAPAARAAAAAAAEAASAPEAAQARERRERGEAARRGAARKAGEGGEQPATEARAD 159
|
170 180
....*....|....*....|....*.
gi 7106671 411 PEARPAPEAAPHPQPDVQPAPQPAQG 436
Cdd:PRK12678 160 AAERTEEEERDERRRRGDREDRQAEA 185
|
|
| MSA-2c |
pfam12238 |
Merozoite surface antigen 2c; This family of proteins is found in eukaryotes. Proteins in this ... |
383-439 |
1.32e-03 |
|
Merozoite surface antigen 2c; This family of proteins is found in eukaryotes. Proteins in this family are typically between 263 and 318 amino acids in length. There is a conserved SFT sequence motif. MSA-2 is a plasma membrane glycoprotein which can be found in Babesia bovis species.
Pssm-ID: 289042 Cd Length: 216 Bit Score: 41.66 E-value: 1.32e-03
10 20 30 40 50
....*....|....*....|....*....|....*....|....*....|....*..
gi 7106671 383 EAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:pfam12238 148 ELQEKKPSRTSSTETPAPGDAESGVQQPPASTPPQGPAPTTPSPSPESSGNLQGQQA 204
|
|
| motB |
PRK05996 |
MotB family protein; |
154-270 |
1.36e-03 |
|
MotB family protein;
Pssm-ID: 235665 [Multi-domain] Cd Length: 423 Bit Score: 42.76 E-value: 1.36e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 154 QAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQAlvtrVATEAVAATGGTPADAGESGEPQ 233
Cdd:PRK05996 189 QVEVTTAGDLLPPGQAREQAQGAKSATAAPATVPQAAPLPQAQPKKAATEEEL----IADAKKAATGEPAANAAKAAKPE 264
|
90 100 110
....*....|....*....|....*....|....*..
gi 7106671 234 EAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPT 270
Cdd:PRK05996 265 PMPDDQQKEAEQLQAAIAQAIGGVAGKLAEGVTVTPV 301
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
88-216 |
1.43e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 42.65 E-value: 1.43e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 88 GGVR---LPDPAQDSATAPVPARRPLHLGPPIPDTSASPVRSLADRGPADAPVRHPGPPTACPEYLDVPQAAVPTPQAAA 164
Cdd:PRK06995 36 GGVEivaLADSDLAALAPPAAAAPAAAQPPPAAAPAAVSRPAAPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQA 115
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|...
gi 7106671 165 PWGAQTAPQAQEVPVNAGAGHAETV-VPVPEQQAAEPVGAAQALVTRVATEAV 216
Cdd:PRK06995 116 PAAPAERAAAENAARRLARAAAAAPrPRVPADAAAAVADAVKARIERIVNDTV 168
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
167-307 |
1.51e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 42.78 E-value: 1.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 167 GAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATggtpadagesgepqeAPAPEAAHTDAg 246
Cdd:PRK14951 369 AAEAAAPAEKKTPARPEAAAPAAAPVAQAAAAPAPAAAPAAAASAPAAPPAAA---------------PPAPVAAPAAA- 432
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106671 247 wPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEE 307
Cdd:PRK14951 433 -APAAAPAAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAARLTPTE 492
|
|
| PHA03247 |
PHA03247 |
large tegument protein UL36; Provisional |
137-321 |
1.83e-03 |
|
large tegument protein UL36; Provisional
Pssm-ID: 223021 [Multi-domain] Cd Length: 3151 Bit Score: 42.62 E-value: 1.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 137 VRHPGPPTACPEYLDVPQAAVPTPQAAAP---WGAQTA------PQAQEVPVNAGAGHA----------ETVVPVPEQQA 197
Cdd:PHA03247 266 DRAPETARGATGPPPPPEAAAPNGAAAPPdgvWGAALAgaplalPAPPDPPPPAPAGDAeeeddedgamEVVSPLPRPRQ 345
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 198 AEPVG--------------------------------AAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDA 245
Cdd:PHA03247 346 HYPLGfpkrrrptwtppssledlsagrhhpkraslptRKRRSARHAATPFARGPGGDDQTRPAAPVPASVPTPAPTPVPA 425
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 7106671 246 GWPVDPAEeavPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAP 321
Cdd:PHA03247 426 SAPPPPAT---PLPSAEPGSDDGPAPPPERQPPAPATEPAPDDPDDATRKALDALRERRPPEPPGADLAELLGRHP 498
|
|
| PHA03169 |
PHA03169 |
hypothetical protein; Provisional |
217-439 |
1.92e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 223003 [Multi-domain] Cd Length: 413 Bit Score: 42.27 E-value: 1.92e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 217 AATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEAlavPEA 296
Cdd:PHA03169 61 VAEQGHRQTESDTETAEESRHGEKEERGQGGPSGSGSESVGSPTPSPSGSAEELASGLSPENTSGSSPESPASH---SPP 137
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 297 QEVPAQSAP-EEAPAEVPAEVPAQAPQGLDEPrvadDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAAAEPEasapeaa 375
Cdd:PHA03169 138 PSPPSHPGPhEPAPPESHNPSPNQQPSSFLQP----SHEDSPEEPEPPTSEPEPDSPGPPQSETPTSSPPPQS------- 206
|
170 180 190 200 210 220
....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 376 apepsvpEAAEPGPAPSPAPEQ-PAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:PHA03169 207 -------PPDEPGEPQSPTPQQaPSPNTQQAVEHEDEPTEPEREGPPFPGHRSHSYTVVGWKPST 264
|
|
| rne |
PRK10811 |
ribonuclease E; Reviewed |
273-535 |
1.96e-03 |
|
ribonuclease E; Reviewed
Pssm-ID: 236766 [Multi-domain] Cd Length: 1068 Bit Score: 42.72 E-value: 1.96e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 273 VTEPVQATAEDDAGPEEALAVPEAQEVPAQsAPEEAPAEVPAevPAQAPQGLDEPRVADDAPEAPAP------------- 339
Cdd:PRK10811 731 IEQSVAEEAVAPVVEETVAAEPVVQEVPAP-RTELVKVPLPV--VAQTAPEQDEENNAENRDNNGMPrrsrrsprhlrvs 807
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 340 -------------QEAPSSLA-----PEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPV 401
Cdd:PRK10811 808 gqrrrryrderypTQSPMPLTvacasPEMASGKVWIRYPVVRPQDVQVEEQREAEEVQVQPVVAEVPVAAAVEPVVSAPV 887
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 402 QVEAAQ---PTPPEARPAPEAAPH---PQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGP 475
Cdd:PRK10811 888 VEAVAEvveEPVVVAEPQPEEVVVvetTHPEVIAAPVTEQPQVITESDVAVAQEVAEHAEPVVEPQDETADIEEAAETAE 967
|
250 260 270 280 290 300
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 476 VAADAPATGAQEPAPVPAPVAQ---EPHPAQPVGQflPVDGGQVPTTPHLAPTP------PEAVLVPPE 535
Cdd:PRK10811 968 VVVAEPEVVAQPAAPVVAEVAAeveTVTAVEPEVA--PAQVPEATVEHNHATAPmtrapaPEYVPEAPR 1034
|
|
| PHA03379 |
PHA03379 |
EBNA-3A; Provisional |
153-527 |
2.01e-03 |
|
EBNA-3A; Provisional
Pssm-ID: 223066 [Multi-domain] Cd Length: 935 Bit Score: 42.35 E-value: 2.01e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 153 PQAAVPTPQAAAPWGAQTAPQAQEVPV-NAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATeavAATGGTPADAGESGE 231
Cdd:PHA03379 416 PRPPVEKPRPEVPQSLETATSHGSAQVpEPPPVHDLEPGPLHDQHSMAPCPVAQLPPGPLQD---LEPGDQLPGVVQDGR 492
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 232 PQEAPAPEAAhtdaGWPVDPAEeavPVPEAVPAVPVAPTAPVTEPVqataEDDAGPEEALavpeaqEVPAQSAPEEAPAE 311
Cdd:PHA03379 493 PACAPVPAPA----GPIVRPWE---ASLSQVPGVAFAPVMPQPMPV----EPVPVPTVAL------ERPVCPAPPLIAMQ 555
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 312 VPAEvpaqaPQGLDEPRVA-DDAPEAPAPQEAPSSLAPEPTPGDARAvDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPA 390
Cdd:PHA03379 556 GPGE-----TSGIVRVRERwRPAPWTPNPPRSPSQMSVRDRLARLRA-EAQPYQASVEVQPPQLTQVSPQQPMEYPLEPE 629
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 391 PSPAPEQPAPVQVEAAQ-PTPPEARPAPEAAPHPQPDVQPAPQpaqgpqSLMDATMQQEQEQEQEQEQEQEQEMAAVVVT 469
Cdd:PHA03379 630 QQMFPGSPFSQVADVMRaGGVPAMQPQYFDLPLQQPISQGAPL------APLRASMGPVPPVPATQPQYFDIPLTEPINQ 703
|
330 340 350 360 370
....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 470 DGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQP-VGQFLPVDGGQVPTTPHLAPTPP 527
Cdd:PHA03379 704 GASAAHFLPQQPMEGPLVPERWMFQGATLSQSVRPgVAQSQYFDLPLTQPINHGAPAAH 762
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
233-319 |
2.49e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 42.18 E-value: 2.49e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 233 QEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEddagPEEALAVPEAQEVPAQSAPEEAPAEV 312
Cdd:PRK12270 36 YGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPK----PAAAAAAAAAPAAPPAAAAAAAPAAA 111
|
....*..
gi 7106671 313 PAEVPAQ 319
Cdd:PRK12270 112 AVEDEVT 118
|
|
| PLN03209 |
PLN03209 |
translocon at the inner envelope of chloroplast subunit 62; Provisional |
223-439 |
2.83e-03 |
|
translocon at the inner envelope of chloroplast subunit 62; Provisional
Pssm-ID: 178748 [Multi-domain] Cd Length: 576 Bit Score: 41.84 E-value: 2.83e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 223 PADAGESGEPQEAPAPEAAHTDAGWPVDPA---EEAVPVPEAVPAVPVAPTA------PVTEPV---QATAEDDAGPEEA 290
Cdd:PLN03209 324 PSQRVPPKESDAADGPKPVPTKPVTPEAPSppiEEEPPQPKAVVPRPLSPYTayedlkPPTSPIptpPSSSPASSKSVDA 403
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 291 LAVP-EAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADD--APEAPAPQEAPSSLAPEPTPGDARAV-DAPVAAAE 366
Cdd:PLN03209 404 VAKPaEPDVVPSPGSASNVPEVEPAQVEAKKTRPLSPYARYEDlkPPTSPSPTAPTGVSPSVSSTSSVPAVpDTAPATAA 483
|
170 180 190 200 210 220 230
....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 367 PEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQS 439
Cdd:PLN03209 484 TDAAAPPPANMRPLSPYAVYDDLKPPTSPSPAAPVGKVAPSSTNEVVKVGNSAPPTALADEQHHAQPKPRPLS 556
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
210-290 |
3.07e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.80 E-value: 3.07e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 210 RVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEE 289
Cdd:PRK12270 37 GPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDE 116
|
.
gi 7106671 290 A 290
Cdd:PRK12270 117 V 117
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
144-357 |
3.31e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 41.51 E-value: 3.31e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 144 TACPEYLDVPQAAVPTPQAAAPwgaQTAPQAQEVPVNAGAGHAETVvpvPEQQAAEPVGAAQALvTRVATEAVAATGGTP 223
Cdd:PRK12727 57 TARSDTPATAAAPAPAPQAPTK---PAAPVHAPLKLSANANMSQRQ---RVASAAEDMIAAMAL-RQPVSVPRQAPAAAP 129
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 224 ADAGESGEPQEApapEAAHTDAGWPVDPAEEAVP-VPEAVPAVPVApTAPVTEPVQAtaeddagpeeALAVPEAQEVPAQ 302
Cdd:PRK12727 130 VRAASIPSPAAQ---ALAHAAAVRTAPRQEHALSaVPEQLFADFLT-TAPVPRAPVQ----------APVVAAPAPVPAI 195
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 303 SAPEEAPAEVPAEVPAQapqgLDEPRVADDAPEAPApqeapssLAPEPTPGDARA 357
Cdd:PRK12727 196 AAALAAHAAYAQDDDEQ----LDDDGFDLDDALPQI-------LPPAALPPIVVA 239
|
|
| PRK12727 |
PRK12727 |
flagellar biosynthesis protein FlhF; |
36-218 |
3.51e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 237182 [Multi-domain] Cd Length: 559 Bit Score: 41.51 E-value: 3.51e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 36 ATAEDEDLL--LLPGAQSAWGNEVAPPAPEPVVETVhQPGPHEMSGRDSGSVDLGGVRLPDPAQDSATAPVPARRPLHLG 113
Cdd:PRK12727 43 ASNYDEELVqrALETARSDTPATAAAPAPAPQAPTK-PAAPVHAPLKLSANANMSQRQRVASAAEDMIAAMALRQPVSVP 121
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 114 PPIP-----DTSASPVRSLADRGP----------------------ADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPW 166
Cdd:PRK12727 122 RQAPaaapvRAASIPSPAAQALAHaaavrtaprqehalsavpeqlfADFLTTAPVPRAPVQAPVVAAPAPVPAIAAALAA 201
|
170 180 190 200 210
....*....|....*....|....*....|....*....|....*....|..
gi 7106671 167 GAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAA 218
Cdd:PRK12727 202 HAAYAQDDDEQLDDDGFDLDDALPQILPPAALPPIVVAPAAPAALAAVAAAA 253
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
285-422 |
3.90e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 40.91 E-value: 3.90e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 285 AGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSSLAPEPTPGDARAVDAPVAA 364
Cdd:NF040712 203 PRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPDEATRDAGEPPA 282
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*...
gi 7106671 365 AEPEASAPEAAApepsvPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPH 422
Cdd:NF040712 283 PGAAETPEAAEP-----PAPAPAAPAAPAAPEAEEPARPEPPPAPKPKRRRRRASVPS 335
|
|
| PRK09752 |
PRK09752 |
AIDA-I family autotransporter YfaL; |
404-443 |
4.57e-03 |
|
AIDA-I family autotransporter YfaL;
Pssm-ID: 182059 [Multi-domain] Cd Length: 1250 Bit Score: 41.20 E-value: 4.57e-03
10 20 30 40
....*....|....*....|....*....|....*....|
gi 7106671 404 EAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDA 443
Cdd:PRK09752 917 EVTPPSPPDPDPTPDPDPTPDPDPTPDPEPTPAYQPVLNA 956
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
382-442 |
4.64e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 41.27 E-value: 4.64e-03
10 20 30 40 50 60
....*....|....*....|....*....|....*....|....*....|....*....|.
gi 7106671 382 PEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMD 442
Cdd:PRK14965 395 AAPAAPPPAAAPPVPPAAPARPAAARPAPAPAPPAAAAPPARSADPAAAASAGDRWRAFVA 455
|
|
| PRK08691 |
PRK08691 |
DNA polymerase III subunits gamma and tau; Validated |
197-437 |
5.09e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236333 [Multi-domain] Cd Length: 709 Bit Score: 41.23 E-value: 5.09e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 197 AAEPVGAAQALVTRVA--TEAVAATGGTPADAGESGEPQEAPAPEAAHTdagwPVDPAEEAVPVPEAVPAvpvaptapvt 274
Cdd:PRK08691 357 AFAPLAAASCDANAVIenTELQSPSAQTAEKETAAKKPQPRPEAETAQT----PVQTASAAAMPSEGKTA---------- 422
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 275 EPVQATAEDDAGPEEAlaVPEAQEVPAQSAPEEAPAEVPAEVPAQAPqgldePRVADDAPEAPAPQEAPSSLAPEPTPGD 354
Cdd:PRK08691 423 GPVSNQENNDVPPWED--APDEAQTAAGTAQTSAKSIQTASEAETPP-----ENQVSKNKAADNETDAPLSEVPSENPIQ 495
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 355 ARAVDAPVAAAEPEAsapeaaapepsvpEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPA 434
Cdd:PRK08691 496 ATPNDEAVETETFAH-------------EAPAEPFYGYGFPDNDCPPEDGAEIPPPDWEHAAPADTAGGGADEEAEAGGI 562
|
...
gi 7106671 435 QGP 437
Cdd:PRK08691 563 GGN 565
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
383-477 |
5.55e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.03 E-value: 5.55e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 383 EAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQE 462
Cdd:PRK12270 34 ADYGPGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAV 113
|
90
....*....|....*
gi 7106671 463 MAAVVVTDGTAGPVA 477
Cdd:PRK12270 114 EDEVTPLRGAAAAVA 128
|
|
| PRK13108 |
PRK13108 |
prolipoprotein diacylglyceryl transferase; Reviewed |
259-428 |
5.68e-03 |
|
prolipoprotein diacylglyceryl transferase; Reviewed
Pssm-ID: 237284 [Multi-domain] Cd Length: 460 Bit Score: 40.73 E-value: 5.68e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 259 PEAVPAVPVAPTAPVT-EPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGLDEPRVADDAPEAP 337
Cdd:PRK13108 282 PGALRGSEYVVDEALErEPAELAAAAVASAASAVGPVGPGEPNQPDDVAEAVKAEVAEVTDEVAAESVVQVADRDGESTP 361
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 338 APQEAPSSLAPEPTPGDARAvdapvaaaepEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAP 417
Cdd:PRK13108 362 AVEETSEADIEREQPGDLAG----------QAPAAHQVDAEAASAAPEEPAALASEAHDETEPEVPEKAAPIPDPAKPDE 431
|
170
....*....|.
gi 7106671 418 EAAPHPQPDVQ 428
Cdd:PRK13108 432 LAVAGPGDDPA 442
|
|
| PRK10263 |
PRK10263 |
DNA translocase FtsK; Provisional |
22-534 |
5.69e-03 |
|
DNA translocase FtsK; Provisional
Pssm-ID: 236669 [Multi-domain] Cd Length: 1355 Bit Score: 41.22 E-value: 5.69e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 22 PGVPAPGAYTYLSEATAEDEDLlllPGAQSawGNEVAPPAPEPvvetvHQPGPHEMSGRDSGSVDLGGVRLPDPAQDSAT 101
Cdd:PRK10263 342 QTPPVASVDVPPAQPTVAWQPV---PGPQT--GEPVIAPAPEG-----YPQQSQYAQPAVQYNEPLQQPVQPQQPYYAPA 411
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 102 APVPARRPLHLGPPIPDTSASPVRSLADRGPADAPVRHPGP-PTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVN 180
Cdd:PRK10263 412 AEQPAQQPYYAPAPEQPAQQPYYAPAPEQPVAGNAWQAEEQqSTFAPQSTYQTEQTYQQPAAQEPLYQQPQPVEQQPVVE 491
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 181 AGAGHAETVVPVP----------------EQQAA------EPVGAAQALVTRVATEAVAATGGTPADAG----ESGEPQE 234
Cdd:PRK10263 492 PEPVVEETKPARPplyyfeeveekrarerEQLAAwyqpipEPVKEPEPIKSSLKAPSVAAVPPVEAAAAvsplASGVKKA 571
|
250 260 270 280 290 300 310 320
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 235 APAPEAAHTDAGWPVDPAEEAVPVPEA---------------VPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEV 299
Cdd:PRK10263 572 TLATGAAATVAAPVFSLANSGGPRPQVkegigpqlprpkrirVPTRRELASYGIKLPSQRAAEEKAREAQRNQYDSGDQY 651
|
330 340 350 360 370 380 390 400
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 300 PAQSAPEEAPAEVPAEVPAQAPQGL------DEPRVADDAPEAPAPQEAPSSLApepTPGDARAVDAPVAAAEPEASAPE 373
Cdd:PRK10263 652 NDDEIDAMQQDELARQFAQTQQQRYgeqyqhDVPVNAEDADAAAEAELARQFAQ---TQQQRYSGEQPAGANPFSLDDFE 728
|
410 420 430 440 450 460 470 480
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 374 AAAPEPSVPEA-AEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPDvQPAPQPAQGPQslmdatmqqeqeqe 452
Cdd:PRK10263 729 FSPMKALLDDGpHEPLFTPIVEPVQQPQQPVAPQQQYQQPQQPVAPQPQYQQPQ-QPVAPQPQYQQ-------------- 793
|
490 500 510 520 530 540 550 560
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 453 qeqeqeqeqEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQPVGQ---------FLPVDGGQVPTTPHLA 523
Cdd:PRK10263 794 ---------PQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPQPQYQQPQQPVAPqpqdtllhpLLMRNGDSRPLHKPTT 864
|
570
....*....|.
gi 7106671 524 PTPPEAVLVPP 534
Cdd:PRK10263 865 PLPSLDLLTPP 875
|
|
| PRK07994 |
PRK07994 |
DNA polymerase III subunits gamma and tau; Validated |
93-240 |
5.78e-03 |
|
DNA polymerase III subunits gamma and tau; Validated
Pssm-ID: 236138 [Multi-domain] Cd Length: 647 Bit Score: 41.00 E-value: 5.78e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 93 PDPAQDSATAPVPARRPLHLGPPIPDTSASPVRSLADRGPADAPVRHPGPPTAcpEYLDVPQAAVPTPQAAAPWGAQTAP 172
Cdd:PRK07994 368 PEVPPQSAAPAASAQATAAPTAAVAPPQAPAVPPPPASAPQQAPAVPLPETTS--QLLAARQQLQRAQGATKAKKSEPAA 445
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 173 QAQEVPVNAGAGHAETVVPVPEQQAAEPVGA-AQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEA 240
Cdd:PRK07994 446 ASRARPVNSALERLASVRPAPSALEKAPAKKeAYRWKATNPVEVKKEPVATPKALKKALEHEKTPELAA 514
|
|
| PRK14960 |
PRK14960 |
DNA polymerase III subunit gamma/tau; |
397-441 |
5.81e-03 |
|
DNA polymerase III subunit gamma/tau;
Pssm-ID: 237868 [Multi-domain] Cd Length: 702 Bit Score: 40.80 E-value: 5.81e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 7106671 397 QPAPVQVEAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGpQSLM 441
Cdd:PRK14960 406 QPAMVEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPEPQPN-QDLM 449
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
263-358 |
5.94e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 41.03 E-value: 5.94e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 263 PAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGldeprvADDAPEAPAPQEA 342
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAA------PPAAAAAAAPAAA 111
|
90
....*....|....*.
gi 7106671 343 PSSLAPEPTPGDARAV 358
Cdd:PRK12270 112 AVEDEVTPLRGAAAAV 127
|
|
| SepH |
NF040712 |
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces ... |
133-271 |
6.46e-03 |
|
septation protein SepH; Septation protein H (SepH) was firstly characterized in Streptomyces venezuelae, and homologs were identified in Mycobacterium smegmatis. SepH contains a N-terminal DUF3071 domain and a conserved C-terminal region. It binds directly to cell division protein FtsZ to stimulate the assembly of FtsZ protofilaments.
Pssm-ID: 468676 [Multi-domain] Cd Length: 346 Bit Score: 40.14 E-value: 6.46e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 133 ADAPVRHPGPPTACPEYLDVPQAAVPTPQAAAPWGAQTAPQAQEVPVNAGAGHAETVVPVPEQQAAEPVGAAQALVTRVA 212
Cdd:NF040712 192 FGRPLRPLATVPRLAREPADARPEEVEPAPAAEGAPATDSDPAEAGTPDDLASARRRRAGVEQPEDEPVGPGAAPAAEPD 271
|
90 100 110 120 130
....*....|....*....|....*....|....*....|....*....|....*....
gi 7106671 213 TEAVAATGGTPADAGESGEPQEAPAPEAAhtdagwPVDPAEEAVPVPEAVPAVPVAPTA 271
Cdd:NF040712 272 EATRDAGEPPAPGAAETPEAAEPPAPAPA------APAAPAAPEAEEPARPEPPPAPKP 324
|
|
| PRK14950 |
PRK14950 |
DNA polymerase III subunits gamma and tau; Provisional |
326-435 |
6.76e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237864 [Multi-domain] Cd Length: 585 Bit Score: 40.56 E-value: 6.76e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 326 EPRVADDAPEAPAPQEAPSSLAPEPTPGDARAvdapvaaaePEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPAPVQVEA 405
Cdd:PRK14950 357 EALLVPVPAPQPAKPTAAAPSPVRPTPAPSTR---------PKAAAAANIPPKEPVRETATPPPVPPRPVAPPVPHTPES 427
|
90 100 110
....*....|....*....|....*....|
gi 7106671 406 AQPTPPEARPAPEAAPHPqpdvQPAPQPAQ 435
Cdd:PRK14950 428 APKLTRAAIPVDEKPKYT----PPAPPKEE 453
|
|
| PLN03237 |
PLN03237 |
DNA topoisomerase 2; Provisional |
183-358 |
7.30e-03 |
|
DNA topoisomerase 2; Provisional
Pssm-ID: 215641 [Multi-domain] Cd Length: 1465 Bit Score: 40.62 E-value: 7.30e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 183 AGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVP---VP 259
Cdd:PLN03237 1214 ASESETTEETYGSSAMETENVAEVVKPKGRAGAKKKAPAAAKEKEEEDEILDLKDRLAAYNLDSAPAQSAKMEETvkaVP 1293
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 260 EAVPAVPVAPTAPVTEPVQATAE-DDAGPEEALAVPEAQEV---PAQSAPEEAPAEVPAEVPA---QAPQGLDEPRVADD 332
Cdd:PLN03237 1294 ARRAAARKKPLASVSVISDSDDDdDDFAVEVSLAERLKKKGgrkPAAANKKAAKPPAAAKKRGpatVQSGQKLLTEMLKP 1373
|
170 180
....*....|....*....|....*..
gi 7106671 333 APEA-PAPQEAPSSLAPEPTPGDARAV 358
Cdd:PLN03237 1374 AEAIgISPEKKVRKMRASPFNKKSGSV 1400
|
|
| PRK14965 |
PRK14965 |
DNA polymerase III subunits gamma and tau; Provisional |
266-355 |
7.54e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237871 [Multi-domain] Cd Length: 576 Bit Score: 40.50 E-value: 7.54e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 266 PVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQSAPEEAPaevPAEVPAQAPQGLDEPRVADDAPEAPAPQEAPSS 345
Cdd:PRK14965 363 PGAPVSELLDRLEALERGAPAPPSAAWGAPTPAAPAAPPPAAAP---PVPPAAPARPAAARPAPAPAPPAAAAPPARSAD 439
|
90
....*....|
gi 7106671 346 LAPEPTPGDA 355
Cdd:PRK14965 440 PAAAASAGDR 449
|
|
| PRK14951 |
PRK14951 |
DNA polymerase III subunits gamma and tau; Provisional |
382-504 |
7.80e-03 |
|
DNA polymerase III subunits gamma and tau; Provisional
Pssm-ID: 237865 [Multi-domain] Cd Length: 618 Bit Score: 40.47 E-value: 7.80e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 382 PEAAEPGPAPSPA-----PEQPAPVQVEAAQPTPPEARPAPEAAPHPQPdVQPAPQPAQGPQSlmdatmQQEQEQEQEQE 456
Cdd:PRK14951 366 PAAAAEAAAPAEKktparPEAAAPAAAPVAQAAAAPAPAAAPAAAASAP-AAPPAAAPPAPVA------APAAAAPAAAP 438
|
90 100 110 120
....*....|....*....|....*....|....*....|....*...
gi 7106671 457 QEQEQEMAAVVVTDGTAGPVAADAPATGAQEPAPVPAPVAQEPHPAQP 504
Cdd:PRK14951 439 AAAPAAVALAPAPPAQAAPETVAIPVRVAPEPAVASAAPAPAAAPAAA 486
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
399-504 |
8.28e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 40.33 E-value: 8.28e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 399 APVQVEAAQPTPPEARPAPEAAPHPQ-PDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVA 477
Cdd:PRK06995 52 APPAAAAPAAAQPPPAAAPAAVSRPAaPAAEPAPWLVEHAKRLTAQREQLVARAAAPAAPEAQAPAAPAERAAAENAARR 131
|
90 100
....*....|....*....|....*..
gi 7106671 478 ADAPATGAQEPaPVPAPVAQEPHPAQP 504
Cdd:PRK06995 132 LARAAAAAPRP-RVPADAAAAVADAVK 157
|
|
| kgd |
PRK12270 |
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine ... |
224-310 |
8.40e-03 |
|
multifunctional oxoglutarate decarboxylase/oxoglutarate dehydrogenase thiamine pyrophosphate-binding subunit/dihydrolipoyllysine-residue succinyltransferase subunit;
Pssm-ID: 237030 [Multi-domain] Cd Length: 1228 Bit Score: 40.64 E-value: 8.40e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 224 ADAGESGEPQEAPAPEAAHTDAGWPVDPAEEAVPVPEAVPAVPVAPTAPVTEPVQATAEDDAGPEEALAVPEAQEVPAQS 303
Cdd:PRK12270 38 PGSTAAPTAAAAAAAAAASAPAAAPAAKAPAAPAPAPPAAAAPAAPPKPAAAAAAAAAPAAPPAAAAAAAPAAAAVEDEV 117
|
....*..
gi 7106671 304 APEEAPA 310
Cdd:PRK12270 118 TPLRGAA 124
|
|
| NfsB-like |
cd02149 |
nitroreductase similar to Escherichia coli NfsB; NAD(P)H:FMN oxidoreductase family. This ... |
668-711 |
8.72e-03 |
|
nitroreductase similar to Escherichia coli NfsB; NAD(P)H:FMN oxidoreductase family. This domain catalyzes the reduction of flavin, nitrocompound, quinones and azo compounds using NADH or NADPH as an electron donor. The enzyme is a homodimer, and each monomer binds a FMN as co-factor. This family includes FRase I in Vibrio fischeri, wihich reduces FMN into FMNH2 as part of the bioluminescent reaction. The family also includes oxygen-insensitive nitroreductases that use NADH or NADPH as an electron donor in the ping pong bi bi mechanism. This type of nitroreductase can be used in cancer chemotherapy to activate a range of prodrugs.
Pssm-ID: 380324 [Multi-domain] Cd Length: 156 Bit Score: 38.39 E-value: 8.72e-03
10 20 30 40
....*....|....*....|....*....|....*....|....
gi 7106671 668 PIPHEVLLRVLEAAHTAPSVGHSQPWDFVVIRSADTRRAMHELA 711
Cdd:cd02149 20 KISDEDLETILEALRLSPSSFGLEPWKFLVVENPELKAKLAPAA 63
|
|
| COG5373 |
COG5373 |
Uncharacterized membrane protein [Function unknown]; |
382-426 |
8.95e-03 |
|
Uncharacterized membrane protein [Function unknown];
Pssm-ID: 444140 [Multi-domain] Cd Length: 854 Bit Score: 40.37 E-value: 8.95e-03
10 20 30 40
....*....|....*....|....*....|....*....|....*
gi 7106671 382 PEAAEPGPAPSPAPEQPAPVQVEAAQPTPPEARPAPEAAPHPQPD 426
Cdd:COG5373 58 ATAAAPEAAPAPVPEAPAAPPAAAEAPAPAAAAPPAEAEPAAAPA 102
|
|
| PHA03307 |
PHA03307 |
transcriptional regulator ICP4; Provisional |
180-494 |
9.02e-03 |
|
transcriptional regulator ICP4; Provisional
Pssm-ID: 223039 [Multi-domain] Cd Length: 1352 Bit Score: 40.54 E-value: 9.02e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 180 NAGAGHAETVVPVPEQQAAEPVGAAQALVTRVATEAVAATGGTPADAGESGEPQEAPAPEaahtdagwpvDPAEEAVPVP 259
Cdd:PHA03307 15 AEGGEFFPRPPATPGDAADDLLSGSQGQLVSDSAELAAVTVVAGAAACDRFEPPTGPPPG----------PGTEAPANES 84
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 260 EAVPAVPVAPTAPVTEPvqATAEDDAGPEEALAVPEAQEVPAQSAPEEAPAEVPAEVPAQAPQGldeprvADDAPEAPAP 339
Cdd:PHA03307 85 RSTPTWSLSTLAPASPA--REGSPTPPGPSSPDPPPPTPPPASPPPSPAPDLSEMLRPVGSPGP------PPAASPPAAG 156
|
170 180 190 200 210 220 230 240
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 340 QEAPSSLAPEPTPGDARAVDAPVAAAEPEASAPEAAAPEPSVPEAAEPGPAPSPAPEQPApvqveaaqptPPEARPAPEA 419
Cdd:PHA03307 157 ASPAAVASDAASSRQAALPLSSPEETARAPSSPPAEPPPSTPPAAASPRPPRRSSPISAS----------ASSPAPAPGR 226
|
250 260 270 280 290 300 310
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 7106671 420 APHPQPDVQPAPQPAQGPQSLMDATMQQEQEQEQEQEQEQEQEMAAVVVTDGTAGPVAAdAPATGAQEPAPVPAP 494
Cdd:PHA03307 227 SAADDAGASSSDSSSSESSGCGWGPENECPLPRPAPITLPTRIWEASGWNGPSSRPGPA-SSSSSPRERSPSPSP 300
|
|
| flhF |
PRK06995 |
flagellar biosynthesis protein FlhF; |
289-445 |
9.66e-03 |
|
flagellar biosynthesis protein FlhF;
Pssm-ID: 235904 [Multi-domain] Cd Length: 484 Bit Score: 39.95 E-value: 9.66e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 289 EALAVPE---AQEVPAQSAPEEAPAEVPAEVPAQAPqgldeprvaddAPEAPAPQEAPSSLAPEPTPGDARAVDAPVaaa 365
Cdd:PRK06995 39 EIVALADsdlAALAPPAAAAPAAAQPPPAAAPAAVS-----------RPAAPAAEPAPWLVEHAKRLTAQREQLVAR--- 104
|
90 100 110 120 130 140 150 160
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 366 epeasapeaaapepsvPEAAEPGPAPSPAPEQPAPvqveAAQPTPPEARPAPEAAPHPQPDVQPAPQPAQGPQSLMDATM 445
Cdd:PRK06995 105 ----------------AAAPAAPEAQAPAAPAERA----AAENAARRLARAAAAAPRPRVPADAAAAVADAVKARIERIV 164
|
|
| PRK04447 |
PRK04447 |
hypothetical protein; Provisional |
999-1127 |
9.77e-03 |
|
hypothetical protein; Provisional
Pssm-ID: 235300 Cd Length: 351 Bit Score: 39.79 E-value: 9.77e-03
10 20 30 40 50 60 70 80
....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 7106671 999 DMTTGTAMTReeAKQAIEVGIETARDLvAAGNKALLTGEM---GiaNTTASAALisvftgadpaevtgRGTGINDETL-- 1073
Cdd:PRK04447 119 DIRTGKAMPR--VEELFERGRLLGKSL-SRPYDYLVIGESvpgG--TTTALAVL--------------TALGYDAAGKvs 179
|
90 100 110 120 130 140
....*....|....*....|....*....|....*....|....*....|....*....|...
gi 7106671 1074 --------ARKTEVVRRALELHQPDPA-DPIGVLAAIGGFEHAAMVGLLLGgASLRTPVILDG 1127
Cdd:PRK04447 180 ssspenphELKRKVVEEGLKRAGLEPKdDPLEAVAAVGDPMQAVVAGLAIG-ASSGGPVLLAG 241
|
|
| |
