NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|702084490|gb|AIW06428|]
View 

putative isopenicillin-n-synthase [Ctenophora sp. W WRF-2014]

Protein Classification

isopenicillin N synthase family oxygenase( domain architecture ID 1002330)

isopenicillin N synthase family oxygenase similar to isopenicillin N synthase, which removes hydrogen atoms from delta-L-(alpha-aminoadipyl)-L-cysteinyl-D-valine (ACV) to form the azetidinone and thiazolidine rings of isopenicillin

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
PcbC super family cl34623
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 60-328 4.51e-24

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


The actual alignment was detected with superfamily member COG3491:

Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 100.65  E-value: 4.51e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  60 HSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDVKADVEIrahnpANANAYRGYCP----GLDD---IDatlqYKN 130
Cdd:COG3491   32 EACREVGFFYVTGhgIPAELIDRLYAAARRFFALPEEEKLKYAI-----PGSPGQRGYTPfggeTAKGakpPD----LKE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 131 IFNIGPHetRAPffdnslDDATEKLRydVQEPNVWPntdncDFDKEFKETFQAGFELRRGIARAFVRSISRALempGLPs 210
Cdd:COG3491  103 FFDIGRE--LPP------DDPDAGPP--LYGPNQWP-----EELPGFREAVLAYYAALEALGRRLLRAFALAL---GLP- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 211 lftEDEFSAM------GLR--KYPERRAvntnmysDFDGELLRELEHVDS-TVTILSTFENGGLQ-MLYNNEYKDAPNSG 280
Cdd:COG3491  164 ---EDYFDDLfddpnsILRliHYPPQPA-------PPPPGQVGAGAHTDYgLLTLLLQDDVGGLQvLTRDGEWIDAPPVP 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 702084490 281 NDFIVNIGKLVDDIIDNELVSVRHRVK--EVDFARYSITYFLGPSFDADI 328
Cdd:COG3491  234 GAFVVNIGDMLERWTNGRLRSTPHRVVnpAAGRERYSIPFFLHPNPDAVI 283
 
Name Accession Description Interval E-value
PcbC COG3491
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 60-328 4.51e-24

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 100.65  E-value: 4.51e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  60 HSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDVKADVEIrahnpANANAYRGYCP----GLDD---IDatlqYKN 130
Cdd:COG3491   32 EACREVGFFYVTGhgIPAELIDRLYAAARRFFALPEEEKLKYAI-----PGSPGQRGYTPfggeTAKGakpPD----LKE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 131 IFNIGPHetRAPffdnslDDATEKLRydVQEPNVWPntdncDFDKEFKETFQAGFELRRGIARAFVRSISRALempGLPs 210
Cdd:COG3491  103 FFDIGRE--LPP------DDPDAGPP--LYGPNQWP-----EELPGFREAVLAYYAALEALGRRLLRAFALAL---GLP- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 211 lftEDEFSAM------GLR--KYPERRAvntnmysDFDGELLRELEHVDS-TVTILSTFENGGLQ-MLYNNEYKDAPNSG 280
Cdd:COG3491  164 ---EDYFDDLfddpnsILRliHYPPQPA-------PPPPGQVGAGAHTDYgLLTLLLQDDVGGLQvLTRDGEWIDAPPVP 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 702084490 281 NDFIVNIGKLVDDIIDNELVSVRHRVK--EVDFARYSITYFLGPSFDADI 328
Cdd:COG3491  234 GAFVVNIGDMLERWTNGRLRSTPHRVVnpAAGRERYSIPFFLHPNPDAVI 283
PTZ00273 PTZ00273
oxidase reductase; Provisional
 60-329 5.67e-15

oxidase reductase; Provisional


Pssm-ID: 140299 [Multi-domain]  Cd Length: 320  Bit Score: 74.79  E-value: 5.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  60 HSMKTYGFFYVV--DVPNYSAEAELELMTTFFGLPEDVKADVEIRahnpaNANAYRGY-CPGLDDID--ATLQYKNIFNI 134
Cdd:PTZ00273  31 EACRTWGFFYIVghPIPQERIEKVLKMAKTFFSLPMEEKLKIDIR-----KSRLHRGYgAFGAEQLDpsKPYDYKETFDM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 135 GPHETRapffDNSLDDATEKLRydvqEPNVWPNTdncdfDKEFKETFQAGFELRRGIARAFVRSISRALempGLPSLFTE 214
Cdd:PTZ00273 106 GCHLPK----DHPDVMAGKPLR----GPNNHPTQ-----VEGWMELMETHYRDMQALALVLLRALALAI---GLREDFFD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 215 DEF----SAMGLRKYPERRAVNtnmysdfDGELLReLEHVD-STVTILSTFENGGLQML-YNNEYKDAPNSGNDFIVNIG 288
Cdd:PTZ00273 170 SKFmeplSVFRMKHYPALPQTK-------KGRTVC-GEHTDyGIITLLYQDSVGGLQVRnLSGEWMDVPPLEGSFVVNIG 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 702084490 289 KLVDDIIDNELVSVRHRVKEVDFARYSITYFLGPSFDADIS 329
Cdd:PTZ00273 242 DMMEMWSNGRYRSTPHRVVNTGVERYSMPFFCEPNPNVIIK 282
2OG-FeII_Oxy pfam03171
2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and ...
 217-322 2.85e-11

2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB.


Pssm-ID: 397334 [Multi-domain]  Cd Length: 101  Bit Score: 59.39  E-value: 2.85e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  217 FSAMGLRKYPErravntnmYSDFDGELLRELEHVDSTVTILSTFENGGLQMLYNNEYKDAPNSGNDFIVNIGKLVDDIID 296
Cdd:pfam03171   2 DQCLVLNYYPP--------HPDPDLTLGLGPHTDASILTILLQDDVGGLQVFKDGKWIDVPPLPGALVVNIGDQLELLSN 73

                          90       100
                  ....*....|....*....|....*...
gi 702084490  297 NELVSVRHRVKEVD--FARYSITYFLGP 322
Cdd:pfam03171  74 GRYKSVLHRVLPVNkgKERISIAFFLRP 101
 
Name Accession Description Interval E-value
PcbC COG3491
Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, ...
 60-328 4.51e-24

Isopenicillin N synthase and related dioxygenases [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 442714 [Multi-domain]  Cd Length: 320  Bit Score: 100.65  E-value: 4.51e-24
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  60 HSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDVKADVEIrahnpANANAYRGYCP----GLDD---IDatlqYKN 130
Cdd:COG3491   32 EACREVGFFYVTGhgIPAELIDRLYAAARRFFALPEEEKLKYAI-----PGSPGQRGYTPfggeTAKGakpPD----LKE 102

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 131 IFNIGPHetRAPffdnslDDATEKLRydVQEPNVWPntdncDFDKEFKETFQAGFELRRGIARAFVRSISRALempGLPs 210
Cdd:COG3491  103 FFDIGRE--LPP------DDPDAGPP--LYGPNQWP-----EELPGFREAVLAYYAALEALGRRLLRAFALAL---GLP- 163

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 211 lftEDEFSAM------GLR--KYPERRAvntnmysDFDGELLRELEHVDS-TVTILSTFENGGLQ-MLYNNEYKDAPNSG 280
Cdd:COG3491  164 ---EDYFDDLfddpnsILRliHYPPQPA-------PPPPGQVGAGAHTDYgLLTLLLQDDVGGLQvLTRDGEWIDAPPVP 233

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 702084490 281 NDFIVNIGKLVDDIIDNELVSVRHRVK--EVDFARYSITYFLGPSFDADI 328
Cdd:COG3491  234 GAFVVNIGDMLERWTNGRLRSTPHRVVnpAAGRERYSIPFFLHPNPDAVI 283
PTZ00273 PTZ00273
oxidase reductase; Provisional
 60-329 5.67e-15

oxidase reductase; Provisional


Pssm-ID: 140299 [Multi-domain]  Cd Length: 320  Bit Score: 74.79  E-value: 5.67e-15
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  60 HSMKTYGFFYVV--DVPNYSAEAELELMTTFFGLPEDVKADVEIRahnpaNANAYRGY-CPGLDDID--ATLQYKNIFNI 134
Cdd:PTZ00273  31 EACRTWGFFYIVghPIPQERIEKVLKMAKTFFSLPMEEKLKIDIR-----KSRLHRGYgAFGAEQLDpsKPYDYKETFDM 105

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 135 GPHETRapffDNSLDDATEKLRydvqEPNVWPNTdncdfDKEFKETFQAGFELRRGIARAFVRSISRALempGLPSLFTE 214
Cdd:PTZ00273 106 GCHLPK----DHPDVMAGKPLR----GPNNHPTQ-----VEGWMELMETHYRDMQALALVLLRALALAI---GLREDFFD 169

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 215 DEF----SAMGLRKYPERRAVNtnmysdfDGELLReLEHVD-STVTILSTFENGGLQML-YNNEYKDAPNSGNDFIVNIG 288
Cdd:PTZ00273 170 SKFmeplSVFRMKHYPALPQTK-------KGRTVC-GEHTDyGIITLLYQDSVGGLQVRnLSGEWMDVPPLEGSFVVNIG 241

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 702084490 289 KLVDDIIDNELVSVRHRVKEVDFARYSITYFLGPSFDADIS 329
Cdd:PTZ00273 242 DMMEMWSNGRYRSTPHRVVNTGVERYSMPFFCEPNPNVIIK 282
2OG-FeII_Oxy pfam03171
2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and ...
 217-322 2.85e-11

2OG-Fe(II) oxygenase superfamily; This family contains members of the 2-oxoglutarate (2OG) and Fe(II)-dependent oxygenase superfamily. This family includes the C-terminal of prolyl 4-hydroxylase alpha subunit. The holoenzyme has the activity EC:1.14.11.2 catalysing the reaction: Procollagen L-proline + 2-oxoglutarate + O2 <=> procollagen trans- 4-hydroxy-L-proline + succinate + CO2. The full enzyme consists of a alpha2 beta2 complex with the alpha subunit contributing most of the parts of the active site. The family also includes lysyl hydrolases, isopenicillin synthases and AlkB.


Pssm-ID: 397334 [Multi-domain]  Cd Length: 101  Bit Score: 59.39  E-value: 2.85e-11
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  217 FSAMGLRKYPErravntnmYSDFDGELLRELEHVDSTVTILSTFENGGLQMLYNNEYKDAPNSGNDFIVNIGKLVDDIID 296
Cdd:pfam03171   2 DQCLVLNYYPP--------HPDPDLTLGLGPHTDASILTILLQDDVGGLQVFKDGKWIDVPPLPGALVVNIGDQLELLSN 73

                          90       100
                  ....*....|....*....|....*...
gi 702084490  297 NELVSVRHRVKEVD--FARYSITYFLGP 322
Cdd:pfam03171  74 GRYKSVLHRVLPVNkgKERISIAFFLRP 101
PLN02984 PLN02984
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 249-331 7.00e-10

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 215534 [Multi-domain]  Cd Length: 341  Bit Score: 59.88  E-value: 7.00e-10
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 249 HVDSTV-TILSTFENGGLQMLYNNEYKDAPNSGNDFIVNIGKLVDDIIDNELVSVRHRVKEV--DFARYSITYFLGPSFD 325
Cdd:PLN02984 222 HTDSSViSILNQDEVGGLEVMKDGEWFNVKPIANTLVVNLGDMMQVISDDEYKSVLHRVGKRnkKKERYSICYFVFPEED 301


                 ....*.
gi 702084490 326 ADISRS 331
Cdd:PLN02984 302 CVIKSS 307
PLN03002 PLN03002
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 39-325 6.21e-07

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 178579 [Multi-domain]  Cd Length: 332  Bit Score: 50.48  E-value: 6.21e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  39 VAKIPYTDLLNDNPYvdpfvlHSMKTY-------GFFYVVD--VPNYSAEAELELMTTFFGLPEDVKADVeirahnpANA 109
Cdd:PLN03002  12 VSSLNCIDLANDDLN------HSVASLkqacldcGFFYVINhgINEEFMDDVFEQSKKFFALPLEEKMKV-------LRN 78

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 110 NAYRGYCPGLDDidaTLQYKNIFNIGPHETRAPFFDNSLDDAT-EKLRYDvqePNVWPNTD-----NCDFDKEFKETFQA 183
Cdd:PLN03002  79 EKHRGYTPVLDE---KLDPKNQINGDHKEGYYIGIEVPKDDPHwDKPFYG---PNPWPDADvlpgwRETMEKYHQEALRV 152

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 184 GFELRRGIARAF---VRSISRAlEMPGLPslftedeFSAMGLRKY-----PERRAVNTNMYSDFdgellrelehvdSTVT 255
Cdd:PLN03002 153 SMAIAKLLALALdldVGYFDRT-EMLGKP-------IATMRLLRYqgisdPSKGIYACGAHSDF------------GMMT 212

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 702084490 256 ILSTFENGGLQMLYN-----NEYKDAPNSGNDFIVNIGKLVDDIIDNELVSVRHRVKEVDFARYSITYFLGPSFD 325
Cdd:PLN03002 213 LLATDGVMGLQICKDknampQKWEYVPPIKGAFIVNLGDMLERWSNGFFKSTLHRVLGNGQERYSIPFFVEPNHD 287
PLN02758 PLN02758
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 65-328 6.27e-07

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 215404 [Multi-domain]  Cd Length: 361  Bit Score: 50.60  E-value: 6.27e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  65 YGFFYVVdvpNYSAEAEL-----ELMTTFFGLPedvkadVEIRAHNPANANAYRGYCPG-LDDIDATLQYKNIFNIGPHe 138
Cdd:PLN02758  83 WGFFQVI---NHGIELELleeieKVAREFFMLP------LEEKQKYPMAPGTVQGYGQAfVFSEDQKLDWCNMFALGVE- 152

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 139 traPFFdnslddateklrydVQEPNVWPNTDncdfdKEFKETFQAGFELRRGIARAFVRSISRALempGLPSLFTEDEFS 218
Cdd:PLN02758 153 ---PHF--------------IRNPKLWPTKP-----ARFSETLEVYSREIRELCQRLLKYIAMTL---GLKEDRFEEMFG 207

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 219 AmglrkypERRAVNTNMYSDFDG-ELLRELE-HVD-STVTILSTFENG--GLQMLYNNEYKDAPNSGNDFIVNIGKLVDD 293
Cdd:PLN02758 208 E-------AVQAVRMNYYPPCSRpDLVLGLSpHSDgSALTVLQQGKGScvGLQILKDNTWVPVHPVPNALVINIGDTLEV 280

                        250       260       270
                 ....*....|....*....|....*....|....*...
gi 702084490 294 IIDNELVSVRHRV---KEVDfaRYSITYFLGPSFDADI 328
Cdd:PLN02758 281 LTNGKYKSVEHRAvtnKEKD--RLSIVTFYAPSYEVEL 316
PLN02912 PLN02912
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 31-329 6.63e-07

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 178500 [Multi-domain]  Cd Length: 348  Bit Score: 50.42  E-value: 6.63e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  31 ESTGvfDSVAKIPYTDLLNDN--PYVDPFVlHSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDvkadvEIRAHNP 106
Cdd:PLN02912  36 ETSG--DSIPLIDLRDLHGPNraDIINQFA-HACSSYGFFQIKNhgVPEETIKKMMNVAREFFHQSES-----ERVKHYS 107

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 107 AnanayrgycpgldDIDATLQYKNIFNIGPhetrapffdNSLDDATEKLR---YDVQE-PNVWPNTDNcdfdkEFKETFQ 182
Cdd:PLN02912 108 A-------------DTKKTTRLSTSFNVSK---------EKVSNWRDFLRlhcYPIEDfIEEWPSTPI-----SFREVTA 160

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 183 AGFELRRGIARAFVRSISRALempGLPSlfteDEFSAMgLRKYPERRAVNtnMYSDF-DGELLRELE-HVDSTV-TILST 259
Cdd:PLN02912 161 EYATSVRALVLTLLEAISESL---GLEK----DRVSNT-LGKHGQHMAIN--YYPPCpQPELTYGLPgHKDANLiTVLLQ 230

                        250       260       270       280       290       300       310
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|.
gi 702084490 260 FENGGLQMLYNNEYKDAPNSGNDFIVNIGKLVDDIIDNELVSVRHR-VKEVDFARYSITYFLGPSFDADIS 329
Cdd:PLN02912 231 DEVSGLQVFKDGKWIAVNPIPNTFIVNLGDQMQVISNDKYKSVLHRaVVNTDKERISIPTFYCPSEDAVIG 301
DIOX_N pfam14226
non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal ...
 58-166 3.14e-06

non-haem dioxygenase in morphine synthesis N-terminal; This is the highly conserved N-terminal region of proteins with 2-oxoglutarate/Fe(II)-dependent dioxygenase activity.


Pssm-ID: 464110 [Multi-domain]  Cd Length: 116  Bit Score: 45.74  E-value: 3.14e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490   58 VLHSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDVKADVeirahnpANANAYRGYCPGLDDI--DATLQYKNIFN 133
Cdd:pfam14226  22 LREACREWGFFQLVNhgVPEELIDELFEAAREFFALPLEEKLKY-------ANPPSFRGYGRLGVEStdGKKLDWKEFFD 94

                          90       100       110
                  ....*....|....*....|....*....|...
gi 702084490  134 IGPHetrapffdnslddATEKLRYDVQEPNVWP 166
Cdd:pfam14226  95 LGTE-------------LPADPPLPLRGPNQWP 114
PLN02750 PLN02750
oxidoreductase, 2OG-Fe(II) oxygenase family protein
 22-328 1.28e-05

oxidoreductase, 2OG-Fe(II) oxygenase family protein


Pssm-ID: 178351 [Multi-domain]  Cd Length: 345  Bit Score: 46.51  E-value: 1.28e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  22 ALIEQLWPNESTGVFDSVAKIPYTDLLNDNPY----VDPFVLHSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLPEDV 95
Cdd:PLN02750   7 AFIQAPEHRPKFHLTNSDEEIPVIDLSVSTSHdkteVASKIGEACKKWGFFQVINhgVPSELRQRVEKVAKEFFDQTTEE 86

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  96 KADVEIRAHNPAnanayrgycpGLDDIDATLQ---YKNIFNIGPHE-TRAPFFDNSLDDATEKLrydvqePNVWPNtdnc 171
Cdd:PLN02750  87 KRKVKRDEVNPM----------GYHDSEHTKNirdWKEVFDFLVQDpTLVPASPDPEDTELRKL------TNQWPQ---- 146

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 172 dFDKEFKETFQAGFELRRGIARAFVRSISRALEMPG--LPSLFtEDEFSAMGLRKYPE----RRAVNTNMYSDfdgellr 245
Cdd:PLN02750 147 -NPSHFRELCQEYARQVEKLAFKLLELISLSLGLPAdrLNGYF-KDQISFARFNHYPPcpapHLALGVGRHKD------- 217

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 246 elehvDSTVTILSTFENGGLQMLYNNE-----YKDAPNSgndFIVNIGKLVDDIIDNELVSVRHRV-----KEvdfaRYS 315
Cdd:PLN02750 218 -----GGALTVLAQDDVGGLQISRRSDgewipVKPIPDA---FIINIGNCMQVWTNDLYWSAEHRVvvnsqKE----RFS 285

                        330
                 ....*....|...
gi 702084490 316 ITYFLGPSFDADI 328
Cdd:PLN02750 286 IPFFFFPSHYVNI 298
PLN02254 PLN02254
gibberellin 3-beta-dioxygenase
 42-329 5.68e-05

gibberellin 3-beta-dioxygenase


Pssm-ID: 215142 [Multi-domain]  Cd Length: 358  Bit Score: 44.69  E-value: 5.68e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490  42 IPYTDLlnDNPYVDPFVLHSMKTYGFFYVVD--VPNYSAEAELELMTTFFGLP--EDVKAdveirAHNPANANAYrgycp 117
Cdd:PLN02254  57 IPVIDL--SDPNALTLIGHACETWGVFQVTNhgIPLSLLDDIESQTRRLFSLPaqRKLKA-----ARSPDGVSGY----- 124

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 118 GLDDIdatlqyknifnigphetrAPFF------------DNSLDDATEklrydvqepnVWPN--TDNCDFDKEFKETFQa 183
Cdd:PLN02254 125 GVARI------------------SSFFnkkmwsegftimGSPLEHARQ----------LWPQdhTKFCDVMEEYQKEMK- 175

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 184 gfelrrGIARafvRSISRALEMPGLpslfTEDEFSAMGLRKYPE--RRAVNTNMYSDF-DGELLREL-EHVDSTV-TILS 258
Cdd:PLN02254 176 ------KLAE---RLMWLMLGSLGI----TEEDIKWAGPKSGSQgaQAALQLNSYPVCpDPDRAMGLaPHTDSSLlTILY 242

                        250       260       270       280       290       300       310       320
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 259 TFENGGLQMLynneyKDA-------PNSGNdFIVNIGKLVDdIIDNELV-SVRHR--VKEVDfARYSITYFLGPSFDADI 328
Cdd:PLN02254 243 QSNTSGLQVF-----REGvgwvtvpPVPGS-LVVNVGDLLH-ILSNGRFpSVLHRavVNKTR-HRISVAYFYGPPSDVQI 314


                 .
gi 702084490 329 S 329
Cdd:PLN02254 315 S 315
PLN02299 PLN02299
1-aminocyclopropane-1-carboxylate oxidase
 249-355 7.14e-05

1-aminocyclopropane-1-carboxylate oxidase


Pssm-ID: 215168 [Multi-domain]  Cd Length: 321  Bit Score: 43.99  E-value: 7.14e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 249 HVDSTVTILsTFEN---GGLQMLYNNEYKDAPNSGNDFIVNIGKLVDDIIDNELVSVRHRV-KEVDFARYSITYFLGPSF 324
Cdd:PLN02299 180 HTDAGGIIL-LFQDdkvSGLQLLKDGEWVDVPPMRHSIVVNLGDQLEVITNGKYKSVMHRVvAQTDGNRMSIASFYNPGS 258

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 702084490 325 DADIS--RSMSGEITEAGHKYT--IFGEWIKDYLG 355
Cdd:PLN02299 259 DAVIYpaPALVEKEAEEEQVYPkfVFEDYMKLYAG 293
PLN02156 PLN02156
gibberellin 2-beta-dioxygenase
 218-329 1.35e-03

gibberellin 2-beta-dioxygenase


Pssm-ID: 177816 [Multi-domain]  Cd Length: 335  Bit Score: 40.37  E-value: 1.35e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 218 SAMGLRKYPERRAVNTNMYSDFDgellrelEHVD-STVTILSTFENGGLQM-LYNNEYKDAPNSGNDFIVNIGKLVDDII 295
Cdd:PLN02156 178 SCLRMNHYPEKEETPEKVEIGFG-------EHTDpQLISLLRSNDTAGLQIcVKDGTWVDVPPDHSSFFVLVGDTLQVMT 250

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 702084490 296 DNELVSVRHRV-KEVDFARYSITYFLGPSFDADIS 329
Cdd:PLN02156 251 NGRFKSVKHRVvTNTKRSRISMIYFAGPPLSEKIA 285
PLN02403 PLN02403
aminocyclopropanecarboxylate oxidase
 242-329 8.27e-03

aminocyclopropanecarboxylate oxidase


Pssm-ID: 178025 [Multi-domain]  Cd Length: 303  Bit Score: 37.53  E-value: 8.27e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 702084490 242 ELLREL-EHVDSTVTILSTFEN--GGLQMLYNNEY-KDAPNSGNDFIVNIGKLVDDIIDNELVSVRHRVKEV-DFARYSI 316
Cdd:PLN02403 167 ELVRGLrEHTDAGGIILLLQDDqvPGLEFLKDGKWvPIPPSKNNTIFVNTGDQLEVLSNGRYKSTLHRVMADkNGSRLSI 246

                         90
                 ....*....|...
gi 702084490 317 TYFLGPSFDADIS 329
Cdd:PLN02403 247 ATFYNPAGDAIIS 259
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH