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Conserved domains on  [gi|695929226|gb|AIT26427|]
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binding--dependent transport system inner membrane component family protein [Bordetella holmesii 44057]

Protein Classification

ABC transporter permease( domain architecture ID 11439449)

ABC transporter permease is the transmembrane (TM) subunit in a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter which generally binds a type 2 PBP; similar to the permease subunit of ABC-type dipeptide/oligopeptide/nickel transport systems

Gene Ontology:  GO:0140359|GO:0042626
PubMed:  25750732|24638992
TCDB:  3.A.1

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 21-302 1.13e-97

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


:

Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 288.94  E-value: 1.13e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  21 RHAQILKKLRSRPTLRGSAFALFILIAVVLLAPFFAPQNPYDLanlNLLDGRLPPrspmmeGGIYWLGTDDQGRDMLSAI 100
Cdd:COG1173    4 RWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQ---DLAARLQPP------SAAHWLGTDQLGRDVLSRL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 101 LYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWA 180
Cdd:COG1173   75 LYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 181 HYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLL 260
Cdd:COG1173  155 GYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTM 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 695929226 261 IANGFQYLLSGdYWISLFPGLALLILILTINIVGDRLRESLD 302
Cdd:COG1173  235 LSEGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 21-302 1.13e-97

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 288.94  E-value: 1.13e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  21 RHAQILKKLRSRPTLRGSAFALFILIAVVLLAPFFAPQNPYDLanlNLLDGRLPPrspmmeGGIYWLGTDDQGRDMLSAI 100
Cdd:COG1173    4 RWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQ---DLAARLQPP------SAAHWLGTDQLGRDVLSRL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 101 LYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWA 180
Cdd:COG1173   75 LYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 181 HYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLL 260
Cdd:COG1173  155 GYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTM 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 695929226 261 IANGFQYLLSGdYWISLFPGLALLILILTINIVGDRLRESLD 302
Cdd:COG1173  235 LSEGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 42-302 9.41e-58

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 186.44  E-value: 9.41e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226   42 LFILIAVVLLAPFFAPQNPydlanlnlLDGRLPPR--SPMMEggiYWLGTDDQGRDMLSAILYGLRISLFVGLSAVALAT 119
Cdd:TIGR02790   8 IAVLFLLAIFAPWIAPHDP--------LAQNLPMRllGPSME---YWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  120 AIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYV 199
Cdd:TIGR02790  77 TIGLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  200 EAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGDYWIsLFP 279
Cdd:TIGR02790 157 LAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLM-IYP 235

                         250       260
                  ....*....|....*....|...
gi 695929226  280 GLALLILILTINIVGDRLRESLD 302
Cdd:TIGR02790 236 GLAILISVMAFNLLGDALRDHLG 258
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
44-304 2.41e-52

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 173.82  E-value: 2.41e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  44 ILIAVVLLAPFFAPQNPYDLANLNLLdgrLPPrsPMMEGGI--YWLGTDDQGRDMLSAILYGLRISLFVGLSAVALATAI 121
Cdd:PRK10913  41 IMLFIAIFANWIAPHNPAEQFRDALL---APP--VWQEGGSwaHILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVM 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 122 GSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYVEA 201
Cdd:PRK10913 116 GVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTA 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 202 AANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGdYWISLFPGL 281
Cdd:PRK10913 196 SRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSA-WWVVTFPGL 274

                        250       260
                 ....*....|....*....|...
gi 695929226 282 ALLILILTINIVGDRLRESLDPR 304
Cdd:PRK10913 275 AILLTVLAFNLMGDGLRDALDPK 297
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 104-271 7.32e-20

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 85.02  E-value: 7.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 104 LRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGR--------GVDKVILALV 175
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVllgwgilpGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 176 IVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEP 255
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170
                 ....*....|....*.
gi 695929226 256 SLGLLIANGFQYLLSG 271
Cdd:cd06261  161 TGLLLIFAILFPGDLG 176
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 122-271 1.12e-15

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 73.49  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  122 GSLVGLVAA-YTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKV----ILALVIVQWAHYARIMRGRALQERRK 196
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHgilpAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695929226  197 EYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFL----GVGVPVTEPSLGLLIANGFQYLLSG 271
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYPEIQGPVLAA 159
 
Name Accession Description Interval E-value
DppC COG1173
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 21-302 1.13e-97

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440786 [Multi-domain]  Cd Length: 275  Bit Score: 288.94  E-value: 1.13e-97
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  21 RHAQILKKLRSRPTLRGSAFALFILIAVVLLAPFFAPQNPYDLanlNLLDGRLPPrspmmeGGIYWLGTDDQGRDMLSAI 100
Cdd:COG1173    4 RWRRAWRRLRRNPLAVIGLVILLLLVLLALFAPLLAPYDPTAQ---DLAARLQPP------SAAHWLGTDQLGRDVLSRL 74

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 101 LYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWA 180
Cdd:COG1173   75 LYGARISLLVGLLAVLIALVIGVLLGLLAGYFGGWVDAVLMRLVDVLLAFPSLLLAIALVAVLGPGLLNVILALGLTGWP 154

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 181 HYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLL 260
Cdd:COG1173  155 GYARLVRAQVLSLREREYVEAARALGASPLRIIFRHILPNVLPPLIVQATLGIASAILAEAGLSFLGLGVQPPTPSWGTM 234

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|..
gi 695929226 261 IANGFQYLLSGdYWISLFPGLALLILILTINIVGDRLRESLD 302
Cdd:COG1173  235 LSEGRNYLLTA-PWLALFPGLAIVLTVLAFNLLGDGLRDALD 275
nickel_nikC TIGR02790
nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of ...
 42-302 9.41e-58

nickel ABC transporter, permease subunit NikC; This family consists of the NikC family of nickel ABC transporter permeases. Operons that contain this protein also contain a homologous permease subunit NikB. Nickel is used in cells as part of urease or certain hydrogenases or superoxide dismutases. [Transport and binding proteins, Cations and iron carrying compounds]


Pssm-ID: 131837 [Multi-domain]  Cd Length: 258  Bit Score: 186.44  E-value: 9.41e-58
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226   42 LFILIAVVLLAPFFAPQNPydlanlnlLDGRLPPR--SPMMEggiYWLGTDDQGRDMLSAILYGLRISLFVGLSAVALAT 119
Cdd:TIGR02790   8 IAVLFLLAIFAPWIAPHDP--------LAQNLPMRllGPSME---YWLGTDHLGRCIFSRLIFGARVSLGSALLVLGLVL 76

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  120 AIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYV 199
Cdd:TIGR02790  77 TIGLLIGGLAGYIGGRVDEAIMRVCDVFLSFPTIILSLAIVGILGPGLENVIIAIVLVHWAWYARMVRGMVVSLKQREFV 156

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  200 EAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGDYWIsLFP 279
Cdd:TIGR02790 157 LAARTSGASHWQIIRRHILPNILSPIIVLATLDIGHVILHIAGLSFLGLGIQPPTPEWGAMLSEAKQYIWTQPLLM-IYP 235

                         250       260
                  ....*....|....*....|...
gi 695929226  280 GLALLILILTINIVGDRLRESLD 302
Cdd:TIGR02790 236 GLAILISVMAFNLLGDALRDHLG 258
PRK10913 PRK10913
dipeptide ABC transporter permease DppC;
44-304 2.41e-52

dipeptide ABC transporter permease DppC;


Pssm-ID: 182833 [Multi-domain]  Cd Length: 300  Bit Score: 173.82  E-value: 2.41e-52
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  44 ILIAVVLLAPFFAPQNPYDLANLNLLdgrLPPrsPMMEGGI--YWLGTDDQGRDMLSAILYGLRISLFVGLSAVALATAI 121
Cdd:PRK10913  41 IMLFIAIFANWIAPHNPAEQFRDALL---APP--VWQEGGSwaHILGTDDVGRDVLSRLMYGARLSLLVGCLVVVLSLVM 115

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 122 GSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYVEA 201
Cdd:PRK10913 116 GVILGLIAGYFGGLVDNIIMRVVDIMLALPSLLLALVLVAIFGPSIVNAALALTFVALPHYVRLTRAAVLVEVNRDYVTA 195

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 202 AANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGdYWISLFPGL 281
Cdd:PRK10913 196 SRVAGAGAMRQMFINILPNCLAPLIVQASLGFSNAILDMAALGFLGMGAQPPTPEWGTMLSDVLQFAQSA-WWVVTFPGL 274

                        250       260
                 ....*....|....*....|...
gi 695929226 282 ALLILILTINIVGDRLRESLDPR 304
Cdd:PRK10913 275 AILLTVLAFNLMGDGLRDALDPK 297
PRK09881 PRK09881
D,D-dipeptide ABC transporter permease;
1-304 4.66e-49

D,D-dipeptide ABC transporter permease;


Pssm-ID: 182131 [Multi-domain]  Cd Length: 296  Bit Score: 164.99  E-value: 4.66e-49
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226   1 MATPSSSGRTRTVAPLAETPRHAQILKklRSRPTLRGSAFALFILIAVVLlAPFFAPQNPydlaNLNLLDGRLPPRSpmm 80
Cdd:PRK09881   2 MLSEETSAVRPQKQTRFNGAKLVWMLK--GSPLTVTGAVIIVLMLLMMIF-SPWLATHDP----NAIDLTARLLPPS--- 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  81 egGIYWLGTDDQGRDMLSAILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLL 160
Cdd:PRK09881  72 --AAHWFGTDEVGRDLFSRVLVGSQQSILAGLVVVAIAGMIGSLLGCLSGVLGGRADAIIMRIMDIMLSIPSLVLTMALA 149

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 161 AMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLE 240
Cdd:PRK09881 150 AALGPSLFNAMLAIAIVRIPFYVRLARGQALVVRQYTYVQAAKTFGASRWHLISWHILRNSLPPLIVQASLDIGSAILMA 229

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 695929226 241 ATLSFLGVGVPVTEPSLGLLIANGFQYLLSgDYWISLFPGLALLILILTINIVGDRLRESLDPR 304
Cdd:PRK09881 230 ATLGFIGLGAQQPSAEWGAMVANGRNYVLD-QWWYCAFPGAAILLTAVGFNLFGDGIRDLLDPK 292
nikC PRK10417
nickel transporter permease NikC; Provisional
 30-303 2.27e-47

nickel transporter permease NikC; Provisional


Pssm-ID: 236687 [Multi-domain]  Cd Length: 272  Bit Score: 159.83  E-value: 2.27e-47
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  30 RSRPTLRGSAFALFILIAVVLLAPFFAPQNPYDLanlNLLDGRLPPrspmmeGGIYWLGTDDQGRDMLSAILYGLRISLF 109
Cdd:PRK10417   1 SSRWSVRLALIIIALLALIALTSQWWLPYDPQAI---DLPSRLLSP------DAQHWLGTDHLGRDIFSRLMAGTRVSLG 71

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 110 VGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGR 189
Cdd:PRK10417  72 SVMACLLLVLALGLVIGGSAGLLGGRVDQATMRVADMFMTFPTSILAFFMVGVLGTGLTNVIIAIALSHWAWYARMVRSL 151

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 190 ALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLL 269
Cdd:PRK10417 152 VISLRQREFVLAARLSGAGHVRVFIDHLLPAVIPQLLVLATLDIGHMMLHVAGLSFLGLGVTAPTAEWGVMINDARQYIW 231

                        250       260       270
                 ....*....|....*....|....*....|....
gi 695929226 270 SGDYWIsLFPGLALLILILTINIVGDRLRESLDP 303
Cdd:PRK10417 232 TQPLLM-FWPGLALFISVMAFNLLGDALRDHLDP 264
PRK15082 PRK15082
glutathione ABC transporter permease GsiD; Provisional
 27-304 1.63e-45

glutathione ABC transporter permease GsiD; Provisional


Pssm-ID: 185040 [Multi-domain]  Cd Length: 301  Bit Score: 156.04  E-value: 1.63e-45
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  27 KKLRSRPTLRGSAFALFILIAVVLLAPFFAP---QNPYDLANLNlldgrlppRSPMMeggIYWLGTDDQGRDMLSAILYG 103
Cdd:PRK15082  30 RRFRRQHVALVAGLFVLLLIVVAIFAPWIAPydaENYFDYDALN--------AGPSL---QHWFGVDSLGRDIFSRILVG 98

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 104 LRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYA 183
Cdd:PRK15082  99 ARISLAAGFFSVAIGAAIGTVLGLLAGYYEGWWDRIIMRICDVLFAFPGILLAIAVVAILGSGMANVIIAVAIFSIPAFA 178

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 184 RIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIAN 263
Cdd:PRK15082 179 RLVRGNTLVLKQQTYIESARSIGASDWTILLRHILPGTVSSIVVYFTMRIGTSIITAASLSFLGLGAQPPTPEWGAMLNE 258

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|.
gi 695929226 264 GFQYLLSGDYwISLFPGLALLILILTINIVGDRLRESLDPR 304
Cdd:PRK15082 259 ARADMVIAPH-VALFPSLAIFLTVLAFNLLGDGLRDALDPK 298
PRK15406 PRK15406
oligopeptide ABC transporter permease OppC; Provisional
 38-304 7.26e-43

oligopeptide ABC transporter permease OppC; Provisional


Pssm-ID: 185304 [Multi-domain]  Cd Length: 302  Bit Score: 149.22  E-value: 7.26e-43
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  38 SAFALFILIAVVLLAPFFAPQNpYDLANLNLLDGrlpprSPMMEGGiYWLGTDDQGRDMLSAILYGLRISLFVGLSAVAL 117
Cdd:PRK15406  42 SLIVLVLIALFVILAPMLSQFA-YDDTDWGMMSS-----APDMESG-HYFGTDSSGRDLLVRVAIGGRISLMVGVAAALV 114

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 118 ATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKE 197
Cdd:PRK15406 115 AVVVGTLYGSLSGYLGGKVDSVMMRLLEILNSFPFMFFVILLVTFFGQNILLIFVAIGMVSWLDMARIVRGQTLSLKRKE 194

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 198 YVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSGDyWISL 277
Cdd:PRK15406 195 FIEAAQVGGVSTRGIVLRHIVPNVLGVVVVYASLLVPSMILFESFLSFLGLGTQEPLSSWGALLSDGANSMEVSP-WLLL 273

                        250       260
                 ....*....|....*....|....*..
gi 695929226 278 FPGLALLILILTINIVGDRLRESLDPR 304
Cdd:PRK15406 274 FPAGFLVVTLFCFNFIGDGLRDALDPK 300
YejE COG4239
ABC-type microcin C transport system, permease component YejE [Secondary metabolites ...
 57-306 4.07e-42

ABC-type microcin C transport system, permease component YejE [Secondary metabolites biosynthesis, transport and catabolism];


Pssm-ID: 443381 [Multi-domain]  Cd Length: 342  Bit Score: 148.38  E-value: 4.07e-42
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  57 PQNPYDLANLNLLDGRLPPRSPMMEggiYWLGTDDQGRDMLSAILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGII 136
Cdd:COG4239   96 PPIPYSYDTINYDLPSPAPSPPSAE---NWLGTDDQGRDVLARLIYGFRISVLFGLALTVISSVIGVAAGAVQGYFGGRV 172

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 137 DAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFH 216
Cdd:COG4239  173 DLLFQRFIEIWSSMPELYLLIILSSIFQPSFWLLLGILLLFGWMGLVGVVRAEFLRARNLEYVRAARALGVSDRRIMFRH 252

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 217 LLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQYLLSgdYWISLFPGLALLILILTINIVGDR 296
Cdd:COG4239  253 ILPNAMVATLTFLPFILSGAITTLTSLDFLGFGLPPGSPSLGELLAQGKNNLQA--PWLGLSAFVVLALMLSLLVFIGEA 330

                        250
                 ....*....|
gi 695929226 297 LRESLDPRRA 306
Cdd:COG4239  331 VRDAFDPRKT 340
SapC COG4171
ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];
24-305 1.39e-31

ABC-type antimicrobial peptide export system, permease component SapC [Defense mechanisms];


Pssm-ID: 443331 [Multi-domain]  Cd Length: 296  Bit Score: 119.15  E-value: 1.39e-31
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  24 QILKKLRSRPTLRGSAFALFILIAVVLLAPFFAPQNPyDLANLNLLdgRLPPrSPMMEGGI-YWLGTDDQGRDMLSAILY 102
Cdd:COG4171   18 QIWQSFRKNPLAMIGLYGFLFLILLALFGPLLAPYSP-DQQFIGAL--LLPP-SWDDNGDVsFFLGTDDLGRDILSRLLY 93

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 103 GLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHY 182
Cdd:COG4171   94 GARYTFGSALLVVLAAAIIGGIIGILAGMSRGLKSSILNHLLDTLLSIPSLLLAIIIVALLGPGLENAMLAITLALLPQF 173

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 183 ARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIA 262
Cdd:COG4171  174 IHAIYQAVHQELKKEYVLAARLDGASNWQLLRYSILPNILEVLVTELTRALSIAILDISALGFLGLGAQLPSPEWGAMLG 253

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*
gi 695929226 263 NGFQ--YLLSgdyWISLFPGLALLILILTINIVGDRLRESLDPRR 305
Cdd:COG4171  254 DSLEliYLAP---WTVILPGLAIMFSVLIVNLVGDGLRRALNKGV 295
PRK15021 PRK15021
microcin C ABC transporter permease; Provisional
 86-306 1.85e-29

microcin C ABC transporter permease; Provisional


Pssm-ID: 184982 [Multi-domain]  Cd Length: 341  Bit Score: 114.70  E-value: 1.85e-29
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  86 WLGTDDQGRDMLSAILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGR 165
Cdd:PRK15021 122 WLGTDANGGDVLARILYGTRISVLFGLMLTLCSSVMGVLAGALQGYYGGKVDLWGQRFIEVWSGMPTLFLIILLSSVVQP 201

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 166 GVDKVILALVIVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSF 245
Cdd:PRK15021 202 NFWWLLAITVLFGWMSLVGVVRAEFLRTRNFDYIRAAQALGVSDRSIILRHMLPNAMVATLTFLPFILCSSITTLTSLDF 281

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 695929226 246 LGVGVPVTEPSLGLLIANGFQYLLSGdyWISLFPGLALLILILTINIVGDRLRESLDPRRA 306
Cdd:PRK15021 282 LGFGLPLGSPSLGELLLQGKNNLQAP--WLGITAFLSVAILLSLLIFIGEAVRDAFDPNKA 340
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 104-271 7.32e-20

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 85.02  E-value: 7.32e-20
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 104 LRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGR--------GVDKVILALV 175
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVllgwgilpGLGLPALILA 80

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 176 IVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEP 255
Cdd:cd06261   81 LLLIAPFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALGEFALVSFLGGGEAPGPG 160

                        170
                 ....*....|....*.
gi 695929226 256 SLGLLIANGFQYLLSG 271
Cdd:cd06261  161 TGLLLIFAILFPGDLG 176
PRK15111 PRK15111
peptide ABC transporter permease SapC;
40-302 4.03e-19

peptide ABC transporter permease SapC;


Pssm-ID: 185066 [Multi-domain]  Cd Length: 296  Bit Score: 85.52  E-value: 4.03e-19
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  40 FALFILIAVVLLAPFFAPqnpYDLANLNLLDGRLPPRSPMMEGGIYWLGTDDQGRDMLSAILYGLRISLFVGLSAVALAT 119
Cdd:PRK15111  34 YGCAGLALLCLFGGWLAP---YGIDQQFLGYQLLPPSWSRYGEVSFFLGTDDLGRDVLSRLLSGAAPTVGGAFVVTLAAT 110

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 120 AIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKVILALVIVQWAHYARIMRGRALQERRKEYV 199
Cdd:PRK15111 111 LCGLVLGVFAGATHGLRSAVLNHILDTLLSIPSLLLAIIVVAFAGPSLSHAMFAVWLALLPRMVRSIYSAVHDELEKEYV 190

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 200 EAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFLGVGVPVTEPSLGLLIANGFQyLLSGDYWISLFP 279
Cdd:PRK15111 191 IAARLDGASTLNILWYAVLPNITAGLVTEITRALSMAILDIAALGFLDLGAQLPSPEWGAMLGDSLE-LIYVAPWTVMLP 269

                        250       260
                 ....*....|....*....|...
gi 695929226 280 GLALLILILTINIVGDRLRESLD 302
Cdd:PRK15111 270 GAAIMLSVLLVNLLGDGIRRAII 292
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 122-271 1.12e-15

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 73.49  E-value: 1.12e-15
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  122 GSLVGLVAA-YTGGIIDAILMRIVDFILGFPTILVALVLLAMMGRGVDKV----ILALVIVQWAHYARIMRGRALQERRK 196
Cdd:pfam00528   1 GIPLGIIAAlRRGRRLDRLLRPLIDLLQALPSFVLAILLVVIAILSILGHgilpAIILALLGWAGYARLIRRAALRSLPS 80

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 695929226  197 EYVEAAANLGFPAWRIMLFHLLPNCLGPVMVFATIQIANAIVLEATLSFL----GVGVPVTEPSLGLLIANGFQYLLSG 271
Cdd:pfam00528  81 DLVEAARALGASRWQIFRKIILPNALPPILTGLALAFGGALGGAVLLEFLgswpGLGLLLIEAILGYDYPEIQGPVLAA 159
DppB COG0601
ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid ...
 92-249 2.31e-14

ABC-type dipeptide/oligopeptide/nickel transport system, permease component [Amino acid transport and metabolism, Inorganic ion transport and metabolism];


Pssm-ID: 440366 [Multi-domain]  Cd Length: 314  Bit Score: 72.02  E-value: 2.31e-14
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  92 QGRDMLSAILYGLRISLFVGLSAVALATAIGSLVGLVAAYT-GGIIDAILMRIVDFILGFPTILVALVLL---------- 160
Cdd:COG0601   83 YGRPVSDLIAERLPVTLELALLALLLALLIGIPLGILAALRrGSWLDRLITVLALLGISIPSFWLGLLLIllfavklgwl 162

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 161 ------AMMGRGVDKV------ILALVIVQWAHYARIMRGRALQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGPVMVF 228
Cdd:COG0601  163 pvsgrvSPWEDFLDALrhlilpALTLALGSLAGIARLTRSSMLEVLGQDYVRTARAKGLSERRVLLRHALRNALIPVVTV 242

                        170       180
                 ....*....|....*....|....*
gi 695929226 229 ATIQIAN----AIVLEATLSFLGVG 249
Cdd:COG0601  243 LGLQLGGllggAVVVETVFSWPGLG 267
HisM COG0765
ABC-type amino acid transport system, permease component [Amino acid transport and metabolism]; ...
 95-219 1.98e-07

ABC-type amino acid transport system, permease component [Amino acid transport and metabolism];


Pssm-ID: 440528 [Multi-domain]  Cd Length: 218  Bit Score: 50.84  E-value: 1.98e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  95 DMLSAILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVL---LAMMGRGVDK-- 169
Cdd:COG0765   10 DYLPLLLEGLLVTLLLTVLAIVLGLVLGLLLALARLSPNPVLRWLATAYVEFFRGTPLLVQLFFIyfgLPLLGIDLSPfv 89

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|.
gi 695929226 170 -VILALVIVQWAHYARIMRGrALQERRKEYVEAAANLGFPAWRIMLFHLLP 219
Cdd:COG0765   90 aAVIALTLNSAAYLAEIVRA-GIQSVPKGQWEAARALGLSRWQTMRRIILP 139
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 98-222 3.84e-04

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 41.25  E-value: 3.84e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226  98 SAILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGGIIDAILMRIVDFILGFPTILVALVLLAM-----MGRGVDKVIL 172
Cdd:COG1177   57 PRLLDALLNSLLIALLSTLLATVLGTPAALALARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLfsalgLSGGLWGLIL 136

                         90       100       110       120       130
                 ....*....|....*....|....*....|....*....|....*....|
gi 695929226 173 ALVIVQWAHYARIMRGRaLQERRKEYVEAAANLGFPAWRIMLFHLLPNCL 222
Cdd:COG1177  137 AHVVFTLPFVVLVVLAR-LQGFDPSLEEAARDLGASPWQTFRRVTLPLIA 185
TauC COG0600
ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion ...
 100-248 3.08e-03

ABC-type nitrate/sulfonate/bicarbonate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440365 [Multi-domain]  Cd Length: 254  Bit Score: 38.59  E-value: 3.08e-03
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 100 ILYGLRISLFVGLSAVALATAIGSLVGLVAAYTGgIIDAILMRIVDFILGFPTILVALVLLAMMGRG-VDKVILALVIVQ 178
Cdd:COG0600   59 LWEHLLASLLRVLLGFALAALLGVPLGLLLGLSR-LLRRLLDPLLVFLRPIPPLALAPLLILWFGIGeASKIFVIFLGAF 137

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 695929226 179 WAHYARIMRGraLQERRKEYVEAAANLGFPAWRIMLFHLLPNCLGpvMVFATIQIAnaivleATLSFLGV 248
Cdd:COG0600  138 FPILLNTAAG--VRSVDPELLELARSLGASRWQILRKVVLPAALP--YIFTGLRIA------LGLAWIGL 197
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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