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Conserved domains on  [gi|6912630|ref|NP_036552|]
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interferon-induced protein with tetratricopeptide repeats 5 [Homo sapiens]

Protein Classification

tetratricopeptide repeat protein( domain architecture ID 13821208)

tetratricopeptide repeat (TPR) protein such as human interferon-induced protein with tetratricopeptide repeats 5 (IFIT5), an interferon-induced RNA-binding protein involved in the innate immune response

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-423 4.39e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


:

Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.31  E-value: 4.39e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG2956  24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkgKDKLK 315
Cdd:COG2956  97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  316 vdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEfHRKSENT 395
Cdd:COG2956 163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ----DPDYLPALPRLAELYE-KLGDPEE 230

                       250       260
                ....*....|....*....|....*...
gi 6912630  396 AIHHYLEALKVKDRSPLRTKLTSALKKL 423
Cdd:COG2956 231 ALELLRKALELDPSDDLLLALADLLERK 258
TPR_12 pfam13424
Tetratricopeptide repeat;
49-116 4.16e-05

Tetratricopeptide repeat;


:

Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 4.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630     49 SRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHsDKEEVRSLVTWGNYAWVYYHMDQLEEAQKY 116
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLL-GPDHPLTATTLLNLGRLYLELGRYEEALEL 67
NrfG super family cl34742
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 434-475 2.93e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


The actual alignment was detected with superfamily member COG4235:

Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 2.93e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 6912630  434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:COG4235  16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-423 4.39e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.31  E-value: 4.39e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG2956  24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkgKDKLK 315
Cdd:COG2956  97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  316 vdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEfHRKSENT 395
Cdd:COG2956 163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ----DPDYLPALPRLAELYE-KLGDPEE 230

                       250       260
                ....*....|....*....|....*...
gi 6912630  396 AIHHYLEALKVKDRSPLRTKLTSALKKL 423
Cdd:COG2956 231 ALELLRKALELDPSDDLLLALADLLERK 258
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 157-470 8.46e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 8.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    157 QKAKAAFEKALEVEPDNPEfnigyaiTVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEK 236
Cdd:TIGR02917 618 NKAVSSFKKLLALQPDSAL-------ALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKK 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLhhqMGLcYRAQMiqikkATHNRPKGKDKLkv 316
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA---IKL-HRALL-----ASGNTAEAVKTL-- 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    317 delissaifhfKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitddHKHQIHYHYGRFQEFHRKSENTA 396
Cdd:TIGR02917 760 -----------EAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK------APDNAVVLNNLAWLYLELKDPRA 822

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6912630    397 IHHYLEALKVKDRSPlrtkltsalkklstkrlchnaldvQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470
Cdd:TIGR02917 823 LEYAERALKLAPNIP------------------------AILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAA 872
TPR_12 pfam13424
Tetratricopeptide repeat;
49-116 4.16e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 4.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630     49 SRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHsDKEEVRSLVTWGNYAWVYYHMDQLEEAQKY 116
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLL-GPDHPLTATTLLNLGRLYLELGRYEEALEL 67
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 434-475 2.93e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 2.93e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 6912630  434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:COG4235  16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 435-468 3.50e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 3.50e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6912630     435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
435-468 5.38e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 5.38e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6912630    435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Name Accession Description Interval E-value
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-423 4.39e-17

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 81.31  E-value: 4.39e-17
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG2956  24 PDKAIDLLEEALELDPETVEAHLALGNLYRRRGEYDR-------AIRIHQKLLERDPDRAEALLELAQDYLKAGLLDRAE 96

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkgKDKLK 315
Cdd:COG2956  97 ELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCELAELYLEQ--------------GDYDE 162

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  316 vdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEfHRKSENT 395
Cdd:COG2956 163 -------AIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQ----DPDYLPALPRLAELYE-KLGDPEE 230

                       250       260
                ....*....|....*....|....*...
gi 6912630  396 AIHHYLEALKVKDRSPLRTKLTSALKKL 423
Cdd:COG2956 231 ALELLRKALELDPSDDLLLALADLLERK 258
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 254-478 1.40e-12

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 67.83  E-value: 1.40e-12
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  254 YAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkgkdklkvdELISSAIFHFKAAMER 333
Cdd:COG2956  13 FKGLNYLLNGQPDKAIDLLEEALELDPETVEAHLALGNLYRRR---------------------GEYDRAIRIHQKLLER 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  334 DSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEFHRKSENtAIHHYLEALKVKDRSP-- 411
Cdd:COG2956  72 DPDRAEALLELAQDYLKAGLLDRAEELLEKLLEL----DPDDAEALRLLAEIYEQEGDWEK-AIEVLERLLKLGPENAha 146

                       170       180       190       200       210       220       230
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6912630  412 --------LRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCEL 478
Cdd:COG2956 147 ycelaelyLEQGDYDEAIEALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAEL 221
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 323-482 1.13e-11

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 66.94  E-value: 1.13e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEnitDDHkHQIHYHYGR-FQEFHRKSEntAIHHYL 401
Cdd:COG3914  97 ALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALN---PDF-AEAYLNLGEaLRRLGRLEE--AIAALR 170

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  402 EALKVKDRsplrtkltsalkklstkrlchnalDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLS 481
Cdd:COG3914 171 RALELDPD------------------------NAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQ 226


                .
gi 6912630  482 I 482
Cdd:COG3914 227 A 227
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 156-280 3.65e-11

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 60.98  E-value: 3.65e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG4783  20 YDEAEALLEKALELDPDNPEAFALLGEILLQLGDLDE-------AIVLLHEALELDPDEPEARLNLGLALLKAGDYDEAL 92

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*
gi 6912630  236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTP 280
Cdd:COG4783  93 ALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELDP 137
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
144-369 4.89e-10

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 60.02  E-value: 4.89e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  144 KGWALLKFGgkYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDsdREGSVKSFslgplRKAVTLNPDNSYIKVFLAL 223
Cdd:COG0457  14 LGLAYRRLG--RYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGR--YEEALADY-----EQALELDPDDAEALNNLGL 84

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  224 KLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMiQIKKA 303
Cdd:COG0457  85 ALQALGRYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEKLG-RYEEA 163

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 6912630  304 THNRPKGKDKLKVDELISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEN 369
Cdd:COG0457 164 LELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAILTLAALAELLLLALAL 229
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
208-472 1.78e-09

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 58.09  E-value: 1.78e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  208 VTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHH 287
Cdd:COG0457   1 LELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALELDPDDAEALN 80

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  288 QMGLCYRAQmiqikkathNRPKGkdklkvdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRL 367
Cdd:COG0457  81 NLGLALQAL---------GRYEE------------ALEDYDKALELDPDDAEALYNLGLALLELGRYDEAIEAYERALEL 139

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  368 enitDDHKHQIHYHYGR-FQEFHRKSEntAIHHYLEALKVKDRSPLRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYK 446
Cdd:COG0457 140 ----DPDDADALYNLGIaLEKLGRYEE--ALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQALRKKLAI 213

                       250       260
                ....*....|....*....|....*.
gi 6912630  447 LEGEKRQAAEYYEKAQKIDPENAEFL 472
Cdd:COG0457 214 LTLAALAELLLLALALLLALRLAALA 239
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 156-366 3.62e-09

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 57.82  E-value: 3.62e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG2956  92 LDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEK-------AIEVLERLLKLGPENAHAYCELAELYLEQGDYDEAI 164

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  236 KYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathNRPKGkdklk 315
Cdd:COG2956 165 EALEKALKLDPDCARALLLLAELYLEQGDYEEAIAALERALEQDPDYLPALPRLAELYEKL---------GDPEE----- 230

                       170       180       190       200       210
                ....*....|....*....|....*....|....*....|....*....|.
gi 6912630  316 vdelissAIFHFKAAMERDSMFAFAYTdLANMYAEGGQYSNAEDIFRKALR 366
Cdd:COG2956 231 -------ALELLRKALELDPSDDLLLA-LADLLERKEGLEAALALLERQLR 273
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 232-368 8.36e-09

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 54.04  E-value: 8.36e-09
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  232 AEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkGK 311
Cdd:COG4783  21 DEAEALLEKALELDPDNPEAFALLGEILLQLGDLDEAIVLLHEALELDPDEPEARLNLGLALLKA-------------GD 87

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*..
gi 6912630  312 dklkvdelISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLE 368
Cdd:COG4783  88 --------YDEALALLEKALKLDPEHPEAYLRLARAYRALGRPDEAIAALEKALELD 136
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
54-277 3.40e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 3.40e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630   54 YNLLAYVKHLKGQNKDALECLEQAEEIIQQEHsdkeevrslVTWGNYAWVYYHMDQLEEAQKYTGKIgnvckklsspSNY 133
Cdd:COG0457  11 YNNLGLAYRRLGRYEEAIEDYEKALELDPDDA---------EALYNLGLAYLRLGRYEEALADYEQA----------LEL 71

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  134 KLECPETDCEKGWALLKFGgkYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPD 213
Cdd:COG0457  72 DPDDAEALNNLGLALQALG--RYEEALEDYDKALELDPDDAEALYNLGLALLELGRYDE-------AIEAYERALELDPD 142

                       170       180       190       200       210       220
                ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6912630  214 NSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALE 277
Cdd:COG0457 143 DADALYNLGIALEKLGRYEEALELLEKLEAAALAALLAAALGEAALALAAAEVLLALLLALEQA 206
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 221-386 3.64e-08

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 55.77  E-value: 3.64e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  221 LALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqi 300
Cdd:COG3914  84 AALLLQALGRYEEALALYRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRL---- 159

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  301 kkathNRPkgkdklkvDElissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEniTDDHKHQIHY 380
Cdd:COG3914 160 -----GRL--------EE----AIAALRRALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELD--PDNADAHSNL 220


                ....*.
gi 6912630  381 HYGRFQ 386
Cdd:COG3914 221 LFALRQ 226
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
323-481 3.77e-08

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 54.24  E-value: 3.77e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGR-FQEFHRKSEntAIHHYL 401
Cdd:COG0457  27 AIEDYEKALELDPDDAEALYNLGLAYLRLGRYEEALADYEQALEL----DPDDAEALNNLGLaLQALGRYEE--ALEDYD 100

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  402 EALKVkdrsplrtkltsalkklstkrlchNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLS 481
Cdd:COG0457 101 KALEL------------------------DPDDAEALYNLGLALLELGRYDEAIEAYERALELDPDDADALYNLGIALEK 156
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 323-470 7.61e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 7.61e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEFHRKSEnTAIHHYLE 402
Cdd:COG4235   2 AIARLRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRL----DPDNADALLDLAEALLAAGDTE-EAEELLER 76

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630  403 ALKVkdrsplrtkltsalkklstkrlchNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470
Cdd:COG4235  77 ALAL------------------------DPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADAP 120
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 158-283 7.83e-08

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 51.16  E-value: 7.83e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  158 KAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKY 237
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRLGRYDE-------ALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEEL 73

                        90       100       110       120
                ....*....|....*....|....*....|....*....|....*.
gi 6912630  238 IEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283
Cdd:COG4235  74 LERALALDPDNPEALYLLGLAAFQQGDYAEAIAAWQKLLALLPADA 119
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 157-470 8.46e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 8.46e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    157 QKAKAAFEKALEVEPDNPEfnigyaiTVYRLDDSDREGSVKSFSLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEK 236
Cdd:TIGR02917 618 NKAVSSFKKLLALQPDSAL-------ALLLLADAYAVMKNYAKAITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKK 690

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    237 YIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLhhqMGLcYRAQMiqikkATHNRPKGKDKLkv 316
Cdd:TIGR02917 691 IAKSLQKQHPKAALGFELEGDLYLRQKDYPAAIQAYRKALKRAPSSQNA---IKL-HRALL-----ASGNTAEAVKTL-- 759

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    317 delissaifhfKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitddHKHQIHYHYGRFQEFHRKSENTA 396
Cdd:TIGR02917 760 -----------EAWLKTHPNDAVLRTALAELYLAQKDYDKAIKHYQTVVKK------APDNAVVLNNLAWLYLELKDPRA 822

                         250       260       270       280       290       300       310
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....
gi 6912630    397 IHHYLEALKVKDRSPlrtkltsalkklstkrlchnaldvQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAE 470
Cdd:TIGR02917 823 LEYAERALKLAPNIP------------------------AILDTLGWLLVEKGEADRALPLLRKAVNIAPEAAA 872
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 151-475 8.61e-08

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 54.70  E-value: 8.61e-08
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    151 FGGKYYQKAKAAFEKALEVEPDNPE--FNIG-YAITVYRLDDS-DREGSV-----------------------KSFSLGP 203
Cdd:TIGR02917 476 LGKGDLAKAREAFEKALSIEPDFFPaaANLArIDIQEGNPDDAiQRFEKVltidpknlrailalaglylrtgnEEEAVAW 555

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283
Cdd:TIGR02917 556 LEKAAELNPQEIEPALALAQYYLGKGQLKKALAILNEAADAAPDSPEAWLMLGRAQLAAGDLNKAVSSFKKLLALQPDSA 635

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    284 FLHhqmglcyrAQMIQIKKATHNRPKgkdklkvdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRk 363
Cdd:TIGR02917 636 LAL--------LLLADAYAVMKNYAK-------------AITSLKRALELKPDNTEAQIGLAQLLLAAKRTESAKKIAK- 693

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    364 alRLENITDDHkHQIHYHYGRFQeFHRKSENTAIHHYLEALKVKDRSPLRTKLTSAL-----KKLSTKRLCH----NALD 434
Cdd:TIGR02917 694 --SLQKQHPKA-ALGFELEGDLY-LRQKDYPAAIQAYRKALKRAPSSQNAIKLHRALlasgnTAEAVKTLEAwlktHPND 769

                         330       340       350       360
                  ....*....|....*....|....*....|....*....|.
gi 6912630    435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:TIGR02917 770 AVLRTALAELYLAQKDYDKAIKHYQTVVKKAPDNAVVLNNL 810
TPR COG0457
Tetratricopeptide (TPR) repeat [General function prediction only];
332-480 2.54e-07

Tetratricopeptide (TPR) repeat [General function prediction only];


Pssm-ID: 440225 [Multi-domain]  Cd Length: 245  Bit Score: 51.93  E-value: 2.54e-07
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  332 ERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQEFHRKSENtAIHHYLEALKVKDRsp 411
Cdd:COG0457   2 ELDPDDAEAYNNLGLAYRRLGRYEEAIEDYEKALEL----DPDDAEALYNLGLAYLRLGRYEE-ALADYEQALELDPD-- 74

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 6912630  412 lrtkltsalkklstkrlchnalDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRL 480
Cdd:COG0457  75 ----------------------DAEALNNLGLALQALGRYEEALEDYDKALELDPDDAEALYNLGLALL 121
3a0801s09 TIGR00990
mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) ...
 130-368 1.13e-06

mitochondrial precursor proteins import receptor (72 kDa mitochondrial outermembrane protein) (mitochondrial import receptor for the ADP/ATP carrier) (translocase of outermembrane tom70); [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 273380 [Multi-domain]  Cd Length: 615  Bit Score: 51.14  E-value: 1.13e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    130 PSNYKlECPETDCEKGWALLKFG--------GKYYQKAKAAFEKALEVEPDNPEFNIGYAIT-VYRLDDSDREGSvksfs 200
Cdd:TIGR00990 277 PAGLE-DSNELDEETGNGQLQLGlkspeskaDESYEEAARAFEKALDLGKLGEKEAIALNLRgTFKCLKGKHLEA----- 350

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    201 LGPLRKAVTLNP--DNSYIKvfLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEV 278
Cdd:TIGR00990 351 LADLSKSIELDPrvTQSYIK--RASMNLELGDPDKAEEDFDKALKLNSEDPDIYYHRAQLHFIKGEFAQAGKDYQKSIDL 428

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    279 TPTSSFLHHQMG-LCYRAQMIQIKKATHNRPKGK----------------DKLKVDElissAIFHFKAAMERDSMFAFAY 341
Cdd:TIGR00990 429 DPDFIFSHIQLGvTQYKEGSIASSMATFRRCKKNfpeapdvynyygelllDQNKFDE----AIEKFDTAIELEKETKPMY 504

                         250       260       270
                  ....*....|....*....|....*....|....
gi 6912630    342 TDLANMYAEG-------GQYSNAEDIFRKALRLE 368
Cdd:TIGR00990 505 MNVLPLINKAlalfqwkQDFIEAENLCEKALIID 538
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 156-244 1.46e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 47.31  E-value: 1.46e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDREGSVksfslgpLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG4235  33 YDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEEL-------LERALALDPDNPEALYLLGLAAFQQGDYAEAI 105


                ....*....
gi 6912630  236 KYIEEILDQ 244
Cdd:COG4235 106 AAWQKLLAL 114
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 246-405 1.48e-06

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 47.49  E-value: 1.48e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  246 SSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkGkdklKVDElissAIF 325
Cdd:COG4783   1 AACAEALYALAQALLLAGDYDEAEALLEKALELDPDNPEAFALLGEILLQL-------------G----DLDE----AIV 59

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  326 HFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitdDHKH-QIHYHYGRFQEFHRKSENtAIHHYLEAL 404
Cdd:COG4783  60 LLHEALELDPDEPEARLNLGLALLKAGDYDEALALLEKALKL-----DPEHpEAYLRLARAYRALGRPDE-AIAALEKAL 133


                .
gi 6912630  405 K 405
Cdd:COG4783 134 E 134
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 204-369 2.45e-06

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 49.99  E-value: 2.45e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283
Cdd:COG3914 101 YRRALALNPDNAEALFNLGNLLLALGRLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLEEAIAALRRALELDPDNA 180

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  284 FLHHQMGLCYRAQMiqikkathnrpkgkdklKVDElissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRK 363
Cdd:COG3914 181 EALNNLGNALQDLG-----------------RLEE----AIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEEL 239


                ....*.
gi 6912630  364 ALRLEN 369
Cdd:COG3914 240 LAALAR 245
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 145-470 3.05e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 49.70  E-value: 3.05e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    145 GWALLKFGGkyYQKAKAAFEKALEVEPDNPEFNIGYAITvyRLDDSDREGSVKSfslgpLRKAVTLNPDNSYIKVFLALK 224
Cdd:TIGR02917 370 GEAYLALGD--FEKAAEYLAKATELDPENAAARTQLGIS--KLSQGDPSEAIAD-----LETAAQLDPELGRADLLLILS 440

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    225 lqdvhaeaegekyieeildqissqpyvlryaakfYRRKNSWNKALELLKKALEVTPTSSFLHHqmglcYRAQMIQIKKat 304
Cdd:TIGR02917 441 ----------------------------------YLRSGQFDKALAAAKKLEKKQPDNASLHN-----LLGAIYLGKG-- 479

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    305 hnrpkgkdklkvdeLISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRleniTDDHKHQIHYHYGR 384
Cdd:TIGR02917 480 --------------DLAKAREAFEKALSIEPDFFPAAANLARIDIQEGNPDDAIQRFEKVLT----IDPKNLRAILALAG 541

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    385 FQEFHRKSENTAIhhYLEALKVKDRSPLRTKLTSALKKLSTKRL------CHNALD-----VQSLSALGFVYKLEGEKRQ 453
Cdd:TIGR02917 542 LYLRTGNEEEAVA--WLEKAAELNPQEIEPALALAQYYLGKGQLkkalaiLNEAADaapdsPEAWLMLGRAQLAAGDLNK 619

                         330
                  ....*....|....*..
gi 6912630    454 AAEYYEKAQKIDPENAE 470
Cdd:TIGR02917 620 AVSSFKKLLALQPDSAL 636
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 267-423 4.50e-06

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 46.15  E-value: 4.50e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  267 KALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathNRPKGkdklkvdelissAIFHFKAAMERDSMFAFAYTDLAN 346
Cdd:COG4235   1 EAIARLRQALAANPNDAEGWLLLGRAYLRL---------GRYDE------------ALAAYEKALRLDPDNADALLDLAE 59

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630  347 MYAEGGQYSNAEDIFRKALRLenitdDHKH-QIHYHYGRFQeFHRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKL 423
Cdd:COG4235  60 ALLAAGDTEEAEELLERALAL-----DPDNpEALYLLGLAA-FQQGDYAEAIAAWQKLLALLPADAPARLLEASIAEA 131
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 158-481 5.30e-06

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 48.93  E-value: 5.30e-06
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    158 KAKAAFEKALEVEPDNPEFNIG---YAITVYRLDDS----------------------DREGSVKSF--SLGPLRKAVTL 210
Cdd:TIGR02917 143 LAQKSYEQALAIDPRSLYAKLGlaqLALAENRFDEAralidevltadpgnvdalllkgDLLLSLGNIelALAAYRKAIAL 222

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    211 NPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTP---------- 280
Cdd:TIGR02917 223 RPNNIAVLLALATILIEAGEFEEAEKHADALLKKAPNSPLAHYLKALVDFQKKNYEDARETLQDALKSAPeylpalllag 302

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    281 TSSFLHHQMGLCYrAQMIQIKKATHNRPKGKDKLKVDEL----ISSAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSN 356
Cdd:TIGR02917 303 ASEYQLGNLEQAY-QYLNQILKYAPNSHQARRLLASIQLrlgrVDEAIATLSPALGLDPDDPAALSLLGEAYLALGDFEK 381

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    357 AEDIFRKALRLENITDDHKHQIhyhyGRFQEFHRKSENtAIHHYLEALKVKDRSP----------LRT----KLTSALKK 422
Cdd:TIGR02917 382 AAEYLAKATELDPENAAARTQL----GISKLSQGDPSE-AIADLETAAQLDPELGradlllilsyLRSgqfdKALAAAKK 456

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 6912630    423 LSTKR----LCHNaldvqslsALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLS 481
Cdd:TIGR02917 457 LEKKQpdnaSLHN--------LLGAIYLGKGDLAKAREAFEKALSIEPDFFPAAANLARIDIQ 511
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
259-368 5.51e-06

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 44.78  E-value: 5.51e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  259 YRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQmiqikkathnrpkgkdkLKVDELISsaifhFKAAMERDSMFA 338
Cdd:COG3063   2 YLKLGDLEEAEEYYEKALELDPDNADALNNLGLLLLEQ-----------------GRYDEAIA-----LEKALKLDPNNA 59

                        90       100       110
                ....*....|....*....|....*....|
gi 6912630  339 FAYTDLANMYAEGGQYSNAEDIFRKALRLE 368
Cdd:COG3063  60 EALLNLAELLLELGDYDEALAYLERALELD 89
TadD COG5010
Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, ...
 204-370 1.20e-05

Flp pilus assembly protein TadD, contains TPR repeats [Intracellular trafficking, secretion, and vesicular transport, Extracellular structures];


Pssm-ID: 444034 [Multi-domain]  Cd Length: 155  Bit Score: 45.34  E-value: 1.20e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283
Cdd:COG5010   9 RLPLYLLLLTKLRTLVEKYEAALAGANNTKEDELAAAGRDKLAKAFAIESPSDNLYNKLGDFEESLALLEQALQLDPNNP 88

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  284 FLHHQMGLCYRAQmiqikkathNRPKGkdklkvdelissAIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRK 363
Cdd:COG5010  89 ELYYNLALLYSRS---------GDKDE------------AKEYYEKALALSPDNPNAYSNLAALLLSLGQDDEAKAALQR 147


                ....*..
gi 6912630  364 ALRLENI 370
Cdd:COG5010 148 ALGTSPL 154
Spy COG3914
Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational ...
 48-316 1.73e-05

Predicted O-linked N-acetylglucosamine transferase, SPINDLY family [Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443119 [Multi-domain]  Cd Length: 658  Bit Score: 47.30  E-value: 1.73e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630   48 KSRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHSDKEEvrslvtwgNYAWVYYHMDQLEEAQKYTGKIGNVCKKL 127
Cdd:COG3914  34 AAALAAALGLALLLLAALAEAAAAALLALAAGEAAAAAAALLL--------LAALLELAALLLQALGRYEEALALYRRAL 105

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  128 S-SPSNyklecPETDCEKGWALLKFGgkYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDregsvksFSLGPLRK 206
Cdd:COG3914 106 AlNPDN-----AEALFNLGNLLLALG--RLEEALAALRRALALNPDFAEAYLNLGEALRRLGRLE-------EAIAALRR 171

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  207 AVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLK-----KALEVTPT 281
Cdd:COG3914 172 ALELDPDNAEALNNLGNALQDLGRLEEAIAAYRRALELDPDNADAHSNLLFALRQACDWEVYDRFEEllaalARGPSELS 251

                       250       260       270       280
                ....*....|....*....|....*....|....*....|....*....
gi 6912630  282 SSFLHHQMGL-------CYR--AQMIQIK-----KATHNRPKGKDKLKV 316
Cdd:COG3914 252 PFALLYLPDDdpaellaLARawAQLVAAAaapelPPPPNPRDPDRKLRI 300
TPR_12 pfam13424
Tetratricopeptide repeat;
49-116 4.16e-05

Tetratricopeptide repeat;


Pssm-ID: 315987 [Multi-domain]  Cd Length: 77  Bit Score: 41.60  E-value: 4.16e-05
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630     49 SRLALYNLLAYVKHLKGQNKDALECLEQAEEIIQQEHsDKEEVRSLVTWGNYAWVYYHMDQLEEAQKY 116
Cdd:pfam13424   1 DVATALNNLAAVLRRLGRYDEALELLEKALEIARRLL-GPDHPLTATTLLNLGRLYLELGRYEEALEL 67
HemYx COG3071
Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to ...
 147-466 4.28e-05

Uncharacterized protein HemY, contains HemY_N domain and TPR repeats (unrelated to protoporphyrinogen oxidase HemY) [Function unknown];


Pssm-ID: 442305 [Multi-domain]  Cd Length: 323  Bit Score: 45.29  E-value: 4.28e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  147 ALLKFGGKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNS----YIKVFLA 222
Cdd:COG3071  23 GLLALAEGRYARAEKLLSKAAEHSEAPLLAYLLAARAAQALGDYER-------RDEYLAQALELAPEAElavlLTRAELL 95

                        90       100       110       120       130       140       150       160
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  223 LKLQDVHaeaEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALEL---LKKALEVTPTssflhHQMGLCYRAQMIQ 299
Cdd:COG3071  96 LDQGQAE---QALATLEALRAGAPRHPQVLRLLLQAYRQLGDWEELLELlpaLRKHKALSAE-----EAQALERRAYLGL 167

                       170       180       190       200       210       220       230       240
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  300 IKKATHnrpkGKDKLKvdelisSAIFHFKAAMERDSMFAFAYtdlANMYAEGGQYSNAEDIFRKALrlenitddhkhqih 379
Cdd:COG3071 168 LRQAAR----DAEALK------ALWKALPRAERRDPELAAAY---ARALIALGDHDEAERLLREAL-------------- 220

                       250       260       270       280       290       300       310       320
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  380 yhygrfqefhRKSENTAIHHYLEALKVKDRSPLRTKLTSALKKlstkrlchNALDVQSLSALGFVYKLEGEKRQAAEYYE 459
Cdd:COG3071 221 ----------KRQWDPRLVRLYGRLQGGDPAKQLKRAEKWLKK--------HPNDPDLLLALGRLCLRNQLWGKAREYLE 282


                ....*..
gi 6912630  460 KAQKIDP 466
Cdd:COG3071 283 AALALRP 289
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
323-461 6.22e-05

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 44.14  E-value: 6.22e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  323 AIFHFKAAMERDSMFAFAYTDLANMYAEGGQYSNAEDIFRKALRLEnitDDH------KHQIHYHYGRFQEfhrksentA 396
Cdd:COG4785  92 AIADFDQALELDPDLAEAYNNRGLAYLLLGDYDAALEDFDRALELD---PDYayaylnRGIALYYLGRYEL--------A 160

                        90       100       110       120       130       140
                ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 6912630  397 IHHYLEALKVKDRSPLRTKLTSalkkLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKA 461
Cdd:COG4785 161 IADLEKALELDPNDPERALWLY----LAERKLDPEKALALLLEDWATAYLLQGDTEEARELFKLA 221
LapB COG2956
Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal ...
 337-475 2.67e-04

Lipopolysaccharide biosynthesis regulator YciM/LapB, contains six TPR domains and a C-terminal metal-binding domain [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 442196 [Multi-domain]  Cd Length: 275  Bit Score: 42.79  E-value: 2.67e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  337 FAFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFqeFHRKSENT-AIHHYLEALKVKDRSP---- 411
Cdd:COG2956   7 AALGWYFKGLNYLLNGQPDKAIDLLEEALEL----DPETVEAHLALGNL--YRRRGEYDrAIRIHQKLLERDPDRAeall 80

                        90       100       110       120       130       140       150
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  412 ------LRTKLTSALKKLSTKRLCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:COG2956  81 elaqdyLKAGLLDRAEELLEKLLELDPDDAEALRLLAEIYEQEGDWEKAIEVLERLLKLGPENAHAYCEL 150
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 163-481 2.86e-04

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 43.53  E-value: 2.86e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    163 FEKALEVEPDNPEFNIGYAiTVYrLDDSDREGSVKSfslgpLRKAVTLNPDNSYIKVFLAL------KLQDVHAEAEGEK 236
Cdd:TIGR02917  45 LKNALQKDPNDAEARFLLG-KIY-LALGDYAAAEKE-----LRKALSLGYPKNQVLPLLARayllqgKFQQVLDELPGKT 117

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    237 yieeiLDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTssFLHHQMGLCYRAqmiqikkATHNRPKGKDKLkV 316
Cdd:TIGR02917 118 -----LLDDEGAAELLALRGLAYLGLGQLELAQKSYEQALAIDPR--SLYAKLGLAQLA-------LAENRFDEARAL-I 182

                         170       180       190       200       210       220       230       240
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    317 DELISSAIFHFKA-----------------------AMERDSMFAFAYTDLANMYAEGGQYSNAE---DIFRKALRLENI 370
Cdd:TIGR02917 183 DEVLTADPGNVDAlllkgdlllslgnielalaayrkAIALRPNNIAVLLALATILIEAGEFEEAEkhaDALLKKAPNSPL 262

                         250       260       270       280       290       300       310       320
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    371 TDDHKHQIHYHYGRFQ--------------------------EFHRKSENTAIHHYLEALKVKDRSPLRTKLTsALKKLS 424
Cdd:TIGR02917 263 AHYLKALVDFQKKNYEdaretlqdalksapeylpalllagasEYQLGNLEQAYQYLNQILKYAPNSHQARRLL-ASIQLR 341

                         330       340       350       360       370       380
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630    425 TKR-----------LCHNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTALCELRLS 481
Cdd:TIGR02917 342 LGRvdeaiatlspaLGLDPDDPAALSLLGEAYLALGDFEKAAEYLAKATELDPENAAARTQLGISKLS 409
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 434-475 2.93e-04

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 40.76  E-value: 2.93e-04
                        10        20        30        40
                ....*....|....*....|....*....|....*....|..
gi 6912630  434 DVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:COG4235  16 DAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDL 57
BepA COG4783
Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell ...
 338-475 3.98e-04

Outer membrane protein chaperone/metalloprotease BepA/YfgC, contains M48 and TPR domains [Cell wall/membrane/envelope biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443813 [Multi-domain]  Cd Length: 139  Bit Score: 40.56  E-value: 3.98e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  338 AFAYTDLANMYAEGGQYSNAEDIFRKALRLenitDDHKHQIHYHYGRFQeFHRKSENTAIHHYLEALKVkdrsplrtklt 417
Cdd:COG4783   4 AEALYALAQALLLAGDYDEAEALLEKALEL----DPDNPEAFALLGEIL-LQLGDLDEAIVLLHEALEL----------- 67

                        90       100       110       120       130
                ....*....|....*....|....*....|....*....|....*....|....*...
gi 6912630  418 salkklstkrlchNALDVQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPENAEFLTAL 475
Cdd:COG4783  68 -------------DPDEPEARLNLGLALLKAGDYDEALALLEKALKLDPEHPEAYLRL 112
PilF COG3063
Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];
156-243 8.81e-04

Type IV pilus assembly protein PilF/PilW [Cell motility, Extracellular structures];


Pssm-ID: 442297 [Multi-domain]  Cd Length: 94  Bit Score: 38.61  E-value: 8.81e-04
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  156 YQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfsLGPLRKAVTLNPDNSYIKVFLALKLQDVHAEAEGE 235
Cdd:COG3063   8 LEEAEEYYEKALELDPDNADALNNLGLLLLEQGRYDE--------AIALEKALKLDPNNAEALLNLAELLLELGDYDEAL 79


                ....*...
gi 6912630  236 KYIEEILD 243
Cdd:COG3063  80 AYLERALE 87
NlpI COG4785
Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];
259-367 1.90e-03

Lipoprotein NlpI, contains TPR repeats [Cell wall/membrane/envelope biogenesis];


Pssm-ID: 443815 [Multi-domain]  Cd Length: 223  Bit Score: 39.90  E-value: 1.90e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  259 YRRKNSWNKALELLKKALEVTPTSSFLHHQMGLCYRAQMiqikkathnrpkgkdklKVDElissAIFHFKAAMERDSMFA 338
Cdd:COG4785  83 YDSLGDYDLAIADFDQALELDPDLAEAYNNRGLAYLLLG-----------------DYDA----ALEDFDRALELDPDYA 141

                        90       100
                ....*....|....*....|....*....
gi 6912630  339 FAYTDLANMYAEGGQYSNAEDIFRKALRL 367
Cdd:COG4785 142 YAYLNRGIALYYLGRYELAIADLEKALEL 170
NrfG COG4235
Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, ...
 204-296 1.91e-03

Cytochrome c-type biogenesis protein CcmH/NrfG [Energy production and conversion, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 443378 [Multi-domain]  Cd Length: 131  Bit Score: 38.45  E-value: 1.91e-03
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630  204 LRKAVTLNPDNSYIKVFLALKLQDVHAEAEGEKYIEEILDQISSQPYVLRYAAKFYRRKNSWNKALELLKKALEVTPTSS 283
Cdd:COG4235   6 LRQALAANPNDAEGWLLLGRAYLRLGRYDEALAAYEKALRLDPDNADALLDLAEALLAAGDTEEAEELLERALALDPDNP 85

                        90
                ....*....|...
gi 6912630  284 FLHHQMGLCYRAQ 296
Cdd:COG4235  86 EALYLLGLAAFQQ 98
PEP_TPR_lipo TIGR02917
putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly ...
 146-243 2.63e-03

putative PEP-CTERM system TPR-repeat lipoprotein; This protein family occurs in strictly within a subset of Gram-negative bacterial species with the proposed PEP-CTERM/exosortase system, analogous to the LPXTG/sortase system common in Gram-positive bacteria. This protein occurs in a species if and only if a transmembrane histidine kinase (TIGR02916) and a DNA-binding response regulator (TIGR02915) also occur. The present of tetratricopeptide repeats (TPR) suggests protein-protein interaction, possibly for the regulation of PEP-CTERM protein expression, since many PEP-CTERM proteins in these genomes are preceded by a proposed DNA binding site for the response regulator.


Pssm-ID: 274350 [Multi-domain]  Cd Length: 899  Bit Score: 40.45  E-value: 2.63e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 6912630    146 WALLKfggKYYQKAKAAFEKALEVEPDNPEFNIGYAITVYRLDDSDRegsvksfSLGPLRKAVTLNPDNSYIKVFLALKL 225
Cdd:TIGR02917 812 WLYLE---LKDPRALEYAERALKLAPNIPAILDTLGWLLVEKGEADR-------ALPLLRKAVNIAPEAAAIRYHLALAL 881

                          90
                  ....*....|....*...
gi 6912630    226 QDVHAEAEGEKYIEEILD 243
Cdd:TIGR02917 882 LATGRKAEARKELDKLLN 899
TPR smart00028
Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum ...
 435-468 3.50e-03

Tetratricopeptide repeats; Repeats present in 4 or more copies in proteins. Contain a minimum of 34 amino acids each and self-associate via a "knobs and holes" mechanism.


Pssm-ID: 197478 [Multi-domain]  Cd Length: 34  Bit Score: 35.11  E-value: 3.50e-03
                           10        20        30
                   ....*....|....*....|....*....|....
gi 6912630     435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468
Cdd:smart00028   1 AEALYNLGNAYLKLGDYDEALEYYEKALELDPNN 34
TPR_1 pfam00515
Tetratricopeptide repeat;
435-468 5.38e-03

Tetratricopeptide repeat;


Pssm-ID: 459840 [Multi-domain]  Cd Length: 34  Bit Score: 34.70  E-value: 5.38e-03
                          10        20        30
                  ....*....|....*....|....*....|....
gi 6912630    435 VQSLSALGFVYKLEGEKRQAAEYYEKAQKIDPEN 468
Cdd:pfam00515   1 AKALYNLGNAYFKLGKYDEALEYYEKALELNPNN 34
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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