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Conserved domains on  [gi|691192244|gb|AIR76500|]
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NADH dehydrogenase subunit 4L (mitochondrion) [Eozubovskya planicaudata]

Protein Classification

NADH dehydrogenase subunit 4L( domain architecture ID 10009597)

NADH dehydrogenase subunit 4L is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (complex I) that is believed to belong to the minimal assembly required for catalysis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.81e-22

NADH dehydrogenase subunit 4L; Provisional


:

Pssm-ID: 177218  Cd Length: 89  Bit Score: 82.89  E-value: 1.81e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  3 MFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 691192244 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.81e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 82.89  E-value: 1.81e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  3 MFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 691192244 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
24-94 4.19e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.71  E-value: 4.19e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 691192244  24 RKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDY--FFPVIFLIFSVCEGALGLSILVSMIRSHGNDFFNSFSL 94
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNL 92
 
Name Accession Description Interval E-value
ND4L MTH00162
NADH dehydrogenase subunit 4L; Provisional
 3-91 1.81e-22

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177218  Cd Length: 89  Bit Score: 82.89  E-value: 1.81e-22
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  3 MFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSMIR 82
Cdd:MTH00162  1 MMMLLIFLFMFFSGLLVFLSKRKHLLLMLLSLEFMVLSLFFLLFLYLSFFNYELYFLLFFLTFSVCEGALGLSILVSMIR 80


                ....*....
gi 691192244 83 SHGNDFFNS 91
Cdd:MTH00162 81 SHGNDYFSS 89
ND4L MTH00188
NADH dehydrogenase subunit 4L; Provisional
 1-97 8.96e-14

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177237  Cd Length: 97  Bit Score: 61.14  E-value: 8.96e-14
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  1 MFMFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSM 80
Cdd:MTH00188  1 MFFSMILVILLFVVLGLFTFLLNRKHLLMLLLSLEAIMLSLFWFLLVGLSYMEKELYLSLVLLTFAACEASVGLALLVSL 80

                        90
                ....*....|....*..
gi 691192244 81 IRSHGNDFFNSFSLSLC 97
Cdd:MTH00188 81 IRSHGSDYVSSLNLIKC 97
ND4L MTH00125
NADH dehydrogenase subunit 4L; Provisional
 24-97 1.92e-12

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177184  Cd Length: 98  Bit Score: 57.55  E-value: 1.92e-12
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 691192244 24 RKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFF--PVIFLIFSVCEGALGLSILVSMIRSHGNDFFNSFSLSLC 97
Cdd:MTH00125 23 RTHLMSALLCLESMMLSLFIMLSLWPITTQTPSFTpmPIILLTFSACEAGTGLALLVATTRTHGSDHLKNLNLLQC 98
ND4L MTH00149
NADH dehydrogenase subunit 4L; Provisional
 1-97 5.31e-11

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214434  Cd Length: 97  Bit Score: 54.08  E-value: 5.31e-11
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  1 MFMFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSM 80
Cdd:MTH00149  1 SMFMLLLLSLFGFLMGVFALLFQYKHLLSILLSLEALMLSLLVMMFSSSGLISFSSYLFLIILTFGACEASLGLSLLVSL 80

                        90
                ....*....|....*..
gi 691192244 81 IRSHGNDFFNSFSLSLC 97
Cdd:MTH00149 81 IRLHGNDYVSSLSSLKF 97
ND4L MTH00013
NADH dehydrogenase subunit 4L; Validated
 2-97 2.61e-10

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 133655  Cd Length: 97  Bit Score: 52.06  E-value: 2.61e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  2 FMFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFL-IEFDYDYFFPVIFLIFSVCEGALGLSILVSM 80
Cdd:MTH00013  1 MMSPLFILSISPFISMFNLSLQRKHLLMSLLSLEAMILSLALFIPLSLmFANQVNGMLAIVLLTFGACEASLGLSLLVLM 80

                        90
                ....*....|....*..
gi 691192244 81 IRSHGNDFFNSFSLSLC 97
Cdd:MTH00013 81 TRSYGNDMLKSLTSNKC 97
ND4L MTH00126
NADH dehydrogenase subunit 4L; Provisional
 4-97 2.70e-10

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177185  Cd Length: 98  Bit Score: 52.27  E-value: 2.70e-10
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  4 FSTFTSLLIYFAGVYIYsskRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYF--FPVIFLIFSVCEGALGLSILVSMI 81
Cdd:MTH00126  6 FSFSSAFILGLMGLAFH---RTHLLSALLCLEGMMLSLFIALSLWALQLESTSFsaAPMLLLAFSACEASAGLALLVATA 82

                        90
                ....*....|....*.
gi 691192244 82 RSHGNDFFNSFSLSLC 97
Cdd:MTH00126 83 RTHGTDRLQNLNLLQC 98
ND4L MTH00067
NADH dehydrogenase subunit 4L; Provisional
 24-97 1.73e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177139  Cd Length: 98  Bit Score: 47.68  E-value: 1.73e-08
                        10        20        30        40        50        60        70
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 691192244 24 RKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYFF--PVIFLIFSVCEGALGLSILVSMIRSHGNDFFNSFSLSLC 97
Cdd:MTH00067 23 RTHLLSALLCLEGMMLSLFIALSLWSTQFESLSYFslPMFMLTFSACEASTGLALMVATTRTHGTDHLKNLNLLQC 98
ND4L MTH00107
NADH dehydrogenase subunit 4L; Provisional
 11-97 7.61e-08

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 177169  Cd Length: 98  Bit Score: 45.69  E-value: 7.61e-08
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244 11 LIYFAGVYIYsskRKHLLMVLLSLEYIVLSLFML--IVIFLIEFDYDYFFPVIFLIFSVCEGALGLSILVSMIRSHGNDF 88
Cdd:MTH00107 13 TISLLGLLMY---RSHLMSSLLCLEGMMLSLFIMatLTILNTHFTLASMMPIILLVFAACEAAVGLALLVMVSNTYGTDY 89


                ....*....
gi 691192244 89 FNSFSLSLC 97
Cdd:MTH00107 90 VQNLNLLQC 98
Oxidored_q2 pfam00420
NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;
24-94 4.19e-07

NADH-ubiquinone/plastoquinone oxidoreductase chain 4L;


Pssm-ID: 425672  Cd Length: 95  Bit Score: 43.71  E-value: 4.19e-07
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|...
gi 691192244  24 RKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDY--FFPVIFLIFSVCEGALGLSILVSMIRSHGNDFFNSFSL 94
Cdd:pfam00420 20 RRNLLRVLLSLELMLNAVNLALVLFGRLTADPLpqALILTAIVIAAAEAAVGLALLVRIYRTHGTDDVDSLNL 92
ND4L MTH00181
NADH dehydrogenase subunit 4L; Provisional
 6-95 4.12e-06

NADH dehydrogenase subunit 4L; Provisional


Pssm-ID: 214450  Cd Length: 93  Bit Score: 41.47  E-value: 4.12e-06
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  6 TFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDY--DYFFPVIFLIFSVCEGALGLSILVSMIRS 83
Cdd:MTH00181  2 MFVFISAFILLLLGLSLYKTHLLSLLLCLEGMMLFLFLLLALFSLLSSSssMLMFGLILLTFSACEAVLGLSLLVATNRT 81

                        90
                ....*....|..
gi 691192244 84 HGNDFFNSFSLS 95
Cdd:MTH00181 82 HGSDHLLKFNLL 93
ND4L MTH00043
NADH dehydrogenase subunit 4L; Validated
 3-94 1.90e-05

NADH dehydrogenase subunit 4L; Validated


Pssm-ID: 214410  Cd Length: 98  Bit Score: 39.52  E-value: 1.90e-05
                        10        20        30        40        50        60        70        80
                ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 691192244  3 MFSTFTSLLIYFAGVYIYSSKRKHLLMVLLSLEYIVLSLFMLIVIFLIEFDYDYF--FPVIFLIFSVCEGALGLSILVSM 80
Cdd:MTH00043  2 NIILIIILSSFFLGLLGILINRLHLLSILLCLELLLISLFLNISIWSLNYGNFSNlsFSLLLLTLSACEASIGLSLMVLL 81

                        90
                ....*....|....
gi 691192244 81 IRSHGNDFFNSFSL 94
Cdd:MTH00043 82 SRNHNSDLVASLNL 95
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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