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hypothetical protein H70357_30950 [Paenibacillus sp. FSL H7-0357]
macro domain-containing protein( domain architecture ID 10121048)
macro domain-containing protein functions in the recognition, interpretation, and turnover of ADP-ribose (ADPr) signaling, such as ADP-ribose 1''-phosphate phosphatase that is involved in the metabolism of ADP-ribose 1''-phosphate (Appr1p) which is produced as a consequence of tRNA splicing
List of domain hits
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Name | Accession | Description | Interval | E-value | |||
Macro_Poa1p-like | cd02901 | macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse ... |
2-131 | 3.55e-46 | |||
macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation. : Pssm-ID: 394873 Cd Length: 135 Bit Score: 146.24 E-value: 3.55e-46
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Name | Accession | Description | Interval | E-value | |||
Macro_Poa1p-like | cd02901 | macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse ... |
2-131 | 3.55e-46 | |||
macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation. Pssm-ID: 394873 Cd Length: 135 Bit Score: 146.24 E-value: 3.55e-46
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YmdB | COG2110 | O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ... |
29-130 | 1.28e-09 | |||
O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]; Pssm-ID: 441713 Cd Length: 168 Bit Score: 53.26 E-value: 1.28e-09
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tk.4 | PHA02595 | hypothetical protein; Provisional |
1-137 | 1.58e-09 | |||
hypothetical protein; Provisional Pssm-ID: 222899 Cd Length: 154 Bit Score: 52.77 E-value: 1.58e-09
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A1pp | smart00506 | Appr-1"-p processing enzyme; Function determined by Martzen et al. Extended family detected by ... |
2-124 | 2.96e-09 | |||
Appr-1"-p processing enzyme; Function determined by Martzen et al. Extended family detected by reciprocal PSI-BLAST searches (unpublished results, and Pehrson _ Fuji). Pssm-ID: 214701 Cd Length: 133 Bit Score: 51.54 E-value: 2.96e-09
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Name | Accession | Description | Interval | E-value | |||
Macro_Poa1p-like | cd02901 | macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse ... |
2-131 | 3.55e-46 | |||
macrodomain, Poa1p-like family; Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Members of this family show similarity to the yeast protein Poa1p, reported to be a phosphatase specific for Appr-1"-p, a tRNA splicing metabolite. Poa1p may play a role in tRNA splicing regulation. Pssm-ID: 394873 Cd Length: 135 Bit Score: 146.24 E-value: 3.55e-46
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Macro_SF | cd02749 | macrodomain superfamily; Macrodomains are found in a variety of proteins with diverse cellular ... |
19-127 | 4.92e-12 | |||
macrodomain superfamily; Macrodomains are found in a variety of proteins with diverse cellular functions, as a stand-alone domain or in combination with other domains like in histone macroH2A and some PARPs (poly ADP-ribose polymerases). Macrodomains can recognize ADP-ribose (ADPr) in both its free and protein-linked forms, in related ligands, such as O-acyl-ADP-ribose (OAADPr), and even in ligands unrelated to ADPr. Macrodomains include the yeast macrodomain Poa1 which is a phosphatase of ADP-ribose-1"-phosphate, a by-product of tRNA splicing. Some macrodomains have ADPr-unrelated binding partners such as the coronavirus SUD-N (N-terminal subdomain) and SUD-M (middle subdomain) of the SARS-unique domain (SUD) which bind G-quadruplexes (unusual nucleic-acid structures formed by consecutive guanosine nucleotides). Macrodomains regulate a wide variety of cellular and organismal processes, including DNA damage repair, signal transduction, and immune response. Pssm-ID: 394871 Cd Length: 121 Bit Score: 58.56 E-value: 4.92e-12
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YmdB | COG2110 | O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ... |
29-130 | 1.28e-09 | |||
O-acetyl-ADP-ribose deacetylase (regulator of RNase III), contains Macro domain [Translation, ribosomal structure and biogenesis]; Pssm-ID: 441713 Cd Length: 168 Bit Score: 53.26 E-value: 1.28e-09
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tk.4 | PHA02595 | hypothetical protein; Provisional |
1-137 | 1.58e-09 | |||
hypothetical protein; Provisional Pssm-ID: 222899 Cd Length: 154 Bit Score: 52.77 E-value: 1.58e-09
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A1pp | smart00506 | Appr-1"-p processing enzyme; Function determined by Martzen et al. Extended family detected by ... |
2-124 | 2.96e-09 | |||
Appr-1"-p processing enzyme; Function determined by Martzen et al. Extended family detected by reciprocal PSI-BLAST searches (unpublished results, and Pehrson _ Fuji). Pssm-ID: 214701 Cd Length: 133 Bit Score: 51.54 E-value: 2.96e-09
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Blast search parameters | ||||
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