sarcosine oxidase subunit gamma (SoxG) is part of a heterotetrameric enzyme that catalyzes the oxidative demethylation of sarcosine to yield glycine, hydrogen peroxide and 5,10-methylenetetrahydrofolate
sarcosine oxidase, gamma subunit family, heterotetrameric form; This model describes the gamma ...
60-206
5.25e-35
sarcosine oxidase, gamma subunit family, heterotetrameric form; This model describes the gamma subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. The gamma subunit is the most divergent between operons of the four subunits. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273586 [Multi-domain] Cd Length: 152 Bit Score: 121.08 E-value: 5.25e-35
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that ...
55-206
7.88e-14
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2.
Pssm-ID: 461245 Cd Length: 152 Bit Score: 66.31 E-value: 7.88e-14
sarcosine oxidase, gamma subunit family, heterotetrameric form; This model describes the gamma ...
60-206
5.25e-35
sarcosine oxidase, gamma subunit family, heterotetrameric form; This model describes the gamma subunit of a family of known and putative heterotetrameric sarcosine oxidases. Five operons of such oxidases are found in Mesorhizobium loti and three in Agrobacterium tumefaciens, a high enough copy number to suggest that not all members are share the same function. The model is designated as subfamily rather than equivalog for this reason. The gamma subunit is the most divergent between operons of the four subunits. Sarcosine oxidase catalyzes the oxidative demethylation of sarcosine to glycine. The reaction converts tetrahydrofolate to 5,10-methylene-tetrahydrofolate. The enzyme is known in monomeric and heterotetrameric (alpha,beta,gamma,delta) forms. [Energy metabolism, Amino acids and amines]
Pssm-ID: 273586 [Multi-domain] Cd Length: 152 Bit Score: 121.08 E-value: 5.25e-35
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that ...
55-206
7.88e-14
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2.
Pssm-ID: 461245 Cd Length: 152 Bit Score: 66.31 E-value: 7.88e-14
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, ...
93-208
8.83e-08
Aminomethyltransferase folate-binding domain; This is a family of glycine cleavage T-proteins, part of the glycine cleavage multienzyme complex (GCV) found in bacteria and the mitochondria of eukaryotes. GCV catalyzes the catabolism of glycine in eukaryotes. The T-protein is an aminomethyl transferase.
Pssm-ID: 460255 Cd Length: 254 Bit Score: 51.05 E-value: 8.83e-08
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that ...
7-147
2.10e-06
Sarcosine oxidase, gamma subunit family; Sarcosine oxidase is a hetero-tetrameric enzyme that contains both covalently bound FMN and non-covalently bound FAD and NAD(+). This enzyme catalyzes the oxidative demethylation of sarcosine to yield glycine, H2O2, and 5,10-CH2-tetrahydrofolate (H4folate) in a reaction requiring H4folate and O2.
Pssm-ID: 461245 Cd Length: 152 Bit Score: 45.90 E-value: 2.10e-06
Database: CDSEARCH/cdd Low complexity filter: no Composition Based Adjustment: yes E-value threshold: 0.01
References:
Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
of the residues that compose this conserved feature have been mapped to the query sequence.
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Functional characterization of the conserved domain architecture found on the query.
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if a domain or superfamily has been annotated with functional sites (conserved features),
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The table lists conserved domains identified on the query sequence. Click on the plus sign (+) on the left to display full descriptions, alignments, and scores.
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(labeled illustration) Standard Display shows only the best scoring domain model from each source, in each hit category listed below for each region on the query sequence.
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