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Conserved domains on  [gi|685355389|ref|XP_009112719|]
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homeobox protein HD1 [Brassica rapa]

Protein Classification

KNOX2 and homeodomain domain-containing protein( domain architecture ID 11145408)

protein containing domains KNOX1, KNOX2, and homeodomain

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 238-276 1.94e-18

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


:

Pssm-ID: 428673  Cd Length: 39  Bit Score: 76.79  E-value: 1.94e-18
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389  238 WQQHCKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKR 276
Cdd:pfam05920   1 LYEHLHNPYPSEEEKAELAKETGLSRKQISNWFINARRR 39
KNOX2 pfam03791
KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 86-137 4.59e-16

KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


:

Pssm-ID: 427506  Cd Length: 48  Bit Score: 70.71  E-value: 4.59e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 685355389   86 SHHDRQELDNFLAQYVMVLCSFKEQLQQHVRvhavEAVMACREIENNLHSLT 137
Cdd:pfam03791   1 SVGADPELDQFMEAYCDVLVKYKEELTRPFE----EATEFLREIESQLNSLC 48
KNOX1 pfam03790
KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 31-69 3.26e-14

KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


:

Pssm-ID: 461051  Cd Length: 40  Bit Score: 65.39  E-value: 3.26e-14
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389   31 MKGEIATHPMYEQLLAAHVACLRVATPIDQLPIIEAQLS 69
Cdd:pfam03790   2 IKAKIASHPLYPSLLSAYVDCQKVGAPPEVAARLDEIAQ 40
 
Name Accession Description Interval E-value
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 238-276 1.94e-18

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 76.79  E-value: 1.94e-18
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389  238 WQQHCKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKR 276
Cdd:pfam05920   1 LYEHLHNPYPSEEEKAELAKETGLSRKQISNWFINARRR 39
KNOX2 pfam03791
KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 86-137 4.59e-16

KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


Pssm-ID: 427506  Cd Length: 48  Bit Score: 70.71  E-value: 4.59e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 685355389   86 SHHDRQELDNFLAQYVMVLCSFKEQLQQHVRvhavEAVMACREIENNLHSLT 137
Cdd:pfam03791   1 SVGADPELDQFMEAYCDVLVKYKEELTRPFE----EATEFLREIESQLNSLC 48
KNOX1 pfam03790
KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 31-69 3.26e-14

KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


Pssm-ID: 461051  Cd Length: 40  Bit Score: 65.39  E-value: 3.26e-14
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389   31 MKGEIATHPMYEQLLAAHVACLRVATPIDQLPIIEAQLS 69
Cdd:pfam03790   2 IKAKIASHPLYPSLLSAYVDCQKVGAPPEVAARLDEIAQ 40
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 220-281 4.17e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 57.25  E-value: 4.17e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 685355389 220 KRRAGKLPGDTTTVLKNWWQQHckwPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN 281
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKN---PYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 219-276 1.86e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 55.33  E-value: 1.86e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 685355389   219 RKRRAGKLPGDTTTVLKNWWQQHckwPYPTEDDKAKLVEETGLQLKQINNWFINQRKR 276
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKN---PYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
 
Name Accession Description Interval E-value
Homeobox_KN pfam05920
Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to ...
 238-276 1.94e-18

Homeobox KN domain; This is a homeobox transcription factor KN domain conserved from fungi to human and plants. They were first identified as TALE homeobox genes in eukaryotes, (including KNOX and MEIS genes). They have been recently classified.


Pssm-ID: 428673  Cd Length: 39  Bit Score: 76.79  E-value: 1.94e-18
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389  238 WQQHCKWPYPTEDDKAKLVEETGLQLKQINNWFINQRKR 276
Cdd:pfam05920   1 LYEHLHNPYPSEEEKAELAKETGLSRKQISNWFINARRR 39
KNOX2 pfam03791
KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 86-137 4.59e-16

KNOX2 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


Pssm-ID: 427506  Cd Length: 48  Bit Score: 70.71  E-value: 4.59e-16
                          10        20        30        40        50
                  ....*....|....*....|....*....|....*....|....*....|..
gi 685355389   86 SHHDRQELDNFLAQYVMVLCSFKEQLQQHVRvhavEAVMACREIENNLHSLT 137
Cdd:pfam03791   1 SVGADPELDQFMEAYCDVLVKYKEELTRPFE----EATEFLREIESQLNSLC 48
KNOX1 pfam03790
KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a ...
 31-69 3.26e-14

KNOX1 domain; The MEINOX region is comprised of two domains, KNOX1 and KNOX2. KNOX1 plays a role in suppressing target gene expression. KNOX2, essential for function, is thought to be necessary for homo-dimerization.


Pssm-ID: 461051  Cd Length: 40  Bit Score: 65.39  E-value: 3.26e-14
                          10        20        30
                  ....*....|....*....|....*....|....*....
gi 685355389   31 MKGEIATHPMYEQLLAAHVACLRVATPIDQLPIIEAQLS 69
Cdd:pfam03790   2 IKAKIASHPLYPSLLSAYVDCQKVGAPPEVAARLDEIAQ 40
homeodomain cd00086
Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic ...
 220-281 4.17e-11

Homeodomain; DNA binding domains involved in the transcriptional regulation of key eukaryotic developmental processes; may bind to DNA as monomers or as homo- and/or heterodimers, in a sequence-specific manner.


Pssm-ID: 238039 [Multi-domain]  Cd Length: 59  Bit Score: 57.25  E-value: 4.17e-11
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 685355389 220 KRRAGKLPGDTTTVLKNWWQQHckwPYPTEDDKAKLVEETGLQLKQINNWFINQRKRNWHNN 281
Cdd:cd00086    1 RRKRTRFTPEQLEELEKEFEKN---PYPSREEREELAKELGLTERQVKIWFQNRRAKLKRSE 59
HOX smart00389
Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key ...
 219-276 1.86e-10

Homeodomain; DNA-binding factors that are involved in the transcriptional regulation of key developmental processes


Pssm-ID: 197696 [Multi-domain]  Cd Length: 57  Bit Score: 55.33  E-value: 1.86e-10
                           10        20        30        40        50
                   ....*....|....*....|....*....|....*....|....*....|....*...
gi 685355389   219 RKRRAGKLPGDTTTVLKNWWQQHckwPYPTEDDKAKLVEETGLQLKQINNWFINQRKR 276
Cdd:smart00389   1 KRRKRTSFTPEQLEELEKEFQKN---PYPSREEREELAKKLGLSERQVKVWFQNRRAK 55
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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