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Conserved domains on  [gi|671705155|gb|KFF57081|]
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membrane protein [Bacillus subtilis]

Protein Classification

helix-turn-helix domain-containing protein( domain architecture ID 11444466)

helix-turn-helix domain-containing protein with a DUF4115 domain, similar to cytoskeleton protein RodZ, an inner membrane protein which functions in cell-shape control through regulation of the length of the long axis

Graphical summary

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List of domain hits

 Name Accession Description Interval E-value
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 1-69 1.91e-25

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


:

Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 96.41  E-value: 1.91e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 671705155   1 MTELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEAVGLDADQLF 69
Cdd:COG1426    3 LETIGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDALPGPVYVRGFLRSYARALGLDPEELL 71
DUF4115 pfam13464
Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of ...
 220-279 2.07e-09

Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of proteins containing a helix-turn-helix domain. The function of this domain is unknown.


:

Pssm-ID: 433229 [Multi-domain]  Cd Length: 67  Bit Score: 52.96  E-value: 2.07e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 671705155  220 ELKAADSSWIRVRDENSSSLKEGTLKKDETYkkDITDQKQVEIRTGYAPNLKIKINGKVL 279
Cdd:pfam13464   1 VLTFTGDSWVEVRDADGKVLFEGLLKAGETR--TVTGKPPLTLVLGNAGAVEVSVNGKPV 58
 
Name Accession Description Interval E-value
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 1-69 1.91e-25

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 96.41  E-value: 1.91e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 671705155   1 MTELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEAVGLDADQLF 69
Cdd:COG1426    3 LETIGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDALPGPVYVRGFLRSYARALGLDPEELL 71
HTH_25 pfam13413
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 7-68 7.96e-24

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433187 [Multi-domain]  Cd Length: 62  Bit Score: 91.79  E-value: 7.96e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671705155    7 RLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEAVGLDADQL 68
Cdd:pfam13413   1 RLRAAREARGLSLEDVAERTKIRPRYLEALEEDDFDALPEPVYARGFLRSYARALGLDPEEL 62
DUF4115 pfam13464
Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of ...
 220-279 2.07e-09

Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of proteins containing a helix-turn-helix domain. The function of this domain is unknown.


Pssm-ID: 433229 [Multi-domain]  Cd Length: 67  Bit Score: 52.96  E-value: 2.07e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 671705155  220 ELKAADSSWIRVRDENSSSLKEGTLKKDETYkkDITDQKQVEIRTGYAPNLKIKINGKVL 279
Cdd:pfam13464   1 VLTFTGDSWVEVRDADGKVLFEGLLKAGETR--TVTGKPPLTLVLGNAGAVEVSVNGKPV 58
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-68 3.44e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 37.92  E-value: 3.44e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 671705155   5 GIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKfyvrafIKQYAEAVGLDADQL 68
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLET------LEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-68 3.98e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 37.88  E-value: 3.98e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671705155     7 RLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIipgkfyVRAFIKQYAEAVGLDADQL 68
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKP------SLETLKKLAKALGVSLDEL 56
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 2-44 5.57e-03

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 38.01  E-value: 5.57e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 671705155   2 TELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALE--EGNYDII 44
Cdd:PRK08154  27 AALGERVRTLRARRGMSRKVLAQASGVSERYLAQLEsgQGNVSIL 71
 
Name Accession Description Interval E-value
RodZ COG1426
Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell ...
 1-69 1.91e-25

Cytoskeletal protein RodZ, contains Xre-like HTH and DUF4115 domains [Cell cycle control, cell division, chromosome partitioning];


Pssm-ID: 441035 [Multi-domain]  Cd Length: 71  Bit Score: 96.41  E-value: 1.91e-25
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 671705155   1 MTELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEAVGLDADQLF 69
Cdd:COG1426    3 LETIGELLRQAREAKGLSLEDVAERTKISVSYLEAIEEGDFDALPGPVYVRGFLRSYARALGLDPEELL 71
HTH_25 pfam13413
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 7-68 7.96e-24

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433187 [Multi-domain]  Cd Length: 62  Bit Score: 91.79  E-value: 7.96e-24
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671705155    7 RLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYVRAFIKQYAEAVGLDADQL 68
Cdd:pfam13413   1 RLRAAREARGLSLEDVAERTKIRPRYLEALEEDDFDALPEPVYARGFLRSYARALGLDPEEL 62
DUF4115 pfam13464
Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of ...
 220-279 2.07e-09

Domain of unknown function (DUF4115); This short domain is often found at the C-terminus of proteins containing a helix-turn-helix domain. The function of this domain is unknown.


Pssm-ID: 433229 [Multi-domain]  Cd Length: 67  Bit Score: 52.96  E-value: 2.07e-09
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|
gi 671705155  220 ELKAADSSWIRVRDENSSSLKEGTLKKDETYkkDITDQKQVEIRTGYAPNLKIKINGKVL 279
Cdd:pfam13464   1 VLTFTGDSWVEVRDADGKVLFEGLLKAGETR--TVTGKPPLTLVLGNAGAVEVSVNGKPV 58
HTH_19 pfam12844
Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. ...
 5-69 3.65e-08

Helix-turn-helix domain; Members of this family contains a DNA-binding helix-turn-helix domain. This family contains many example antitoxins from bacterial toxin-antitoxin systems. These antitoxins are likely to be DNA-binding domains.


Pssm-ID: 463728 [Multi-domain]  Cd Length: 64  Bit Score: 49.21  E-value: 3.65e-08
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*
gi 671705155    5 GIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKFYvrafikQYAEAVGLDADQLF 69
Cdd:pfam12844   1 GERLRKAREERGLTQEELAERLGISRSQLSAIENGKSVPPAETLY------KIAELLGVPANWLL 59
HipB COG1396
Transcriptional regulator, contains XRE-family HTH domain [Transcription];
1-79 7.69e-06

Transcriptional regulator, contains XRE-family HTH domain [Transcription];


Pssm-ID: 441006 [Multi-domain]  Cd Length: 83  Bit Score: 43.45  E-value: 7.69e-06
                         10        20        30        40        50        60        70
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....
gi 671705155   1 MTELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPgkfyvrAFIKQYAEAVGLDADQLFEEHKKDIPNT 79
Cdd:COG1396    5 KKALGERLRELRKARGLTQEELAERLGVSRSTISRIERGRRNPSL------ETLLKLAKALGVSLDELLGGADEELPEA 77
HTH_XRE cd00093
Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the ...
 5-68 3.44e-04

Helix-turn-helix XRE-family like proteins. Prokaryotic DNA binding proteins belonging to the xenobiotic response element family of transcriptional regulators.


Pssm-ID: 238045 [Multi-domain]  Cd Length: 58  Bit Score: 37.92  E-value: 3.44e-04
                         10        20        30        40        50        60
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 671705155   5 GIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPGKfyvrafIKQYAEAVGLDADQL 68
Cdd:cd00093    1 GERLKELRKEKGLTQEELAEKLGVSRSTISRIENGKRNPSLET------LEKLAKALGVSLDEL 58
HTH_XRE smart00530
Helix-turn-helix XRE-family like proteins;
7-68 3.98e-04

Helix-turn-helix XRE-family like proteins;


Pssm-ID: 197775 [Multi-domain]  Cd Length: 56  Bit Score: 37.88  E-value: 3.98e-04
                           10        20        30        40        50        60
                   ....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671705155     7 RLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIipgkfyVRAFIKQYAEAVGLDADQL 68
Cdd:smart00530   1 RLKELREEKGLTQEELAEKLGVSRSTLSRIENGKRKP------SLETLKKLAKALGVSLDEL 56
HTH_31 pfam13560
Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.
 3-68 9.69e-04

Helix-turn-helix domain; This domain is a helix-turn-helix domain that probably binds to DNA.


Pssm-ID: 433309 [Multi-domain]  Cd Length: 64  Bit Score: 36.74  E-value: 9.69e-04
                          10        20        30        40        50        60
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*.
gi 671705155    3 ELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALEEGNYDIIPgkfyvRAFIKQYAEAVGLDADQL 68
Cdd:pfam13560   1 ELGARLRRLRERAGLSQEALARRLGVSRSTLSRLETGRRGRPS-----PAVVERLARALGVDGAER 61
PRK08154 PRK08154
anaerobic benzoate catabolism transcriptional regulator; Reviewed
 2-44 5.57e-03

anaerobic benzoate catabolism transcriptional regulator; Reviewed


Pssm-ID: 236167 [Multi-domain]  Cd Length: 309  Bit Score: 38.01  E-value: 5.57e-03
                         10        20        30        40
                 ....*....|....*....|....*....|....*....|....*
gi 671705155   2 TELGIRLKEAREEKAMSLDDLQAATKIQKRYLTALE--EGNYDII 44
Cdd:PRK08154  27 AALGERVRTLRARRGMSRKVLAQASGVSERYLAQLEsgQGNVSIL 71
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
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