NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|671617087|ref|WP_031585827|]
View 

GNAT family N-acetyltransferase [Staphylococcus aureus]

Protein Classification

GNAT family N-acetyltransferase( domain architecture ID 10006981)

GNAT family N-acetyltransferase catalyzes the transfer of an acetyl group from acetyl-CoA to a substrate

CATH:  3.40.630.30
EC:  2.3.-.-
Gene Ontology:  GO:0016746|GO:0008080
PubMed:  27367672|26818562|15581578|10940244
SCOP:  3000403

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
6-163 2.03e-21

Predicted N-acetyltransferase YhbS [General function prediction only];


:

Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 84.75  E-value: 2.03e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   6 IRLASEQDAEKLQQLMHEAFTPLRELGIdwpsvnanLDAVKENIDKNTTFVMTIDDEIISTItvRYPWRSVKSISGYPFV 85
Cdd:COG3153    1 IRPATPEDAEAIAALLRAAFGPGREAEL--------VDRLREDPAAGLSLVAEDDGEIVGHV--ALSPVDIDGEGPALLL 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 671617087  86 WWFATNPEYEGKGYGSQLLTYVEEAfLRDtLKSAAVTLGTSARLHPWllkiYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:COG3153   71 GPLAVDPEYRGQGIGRALMRAALEA-ARE-RGARAVVLLGDPSLLPF----YERFGFRPAGELGLTLGPDEVFLAKEL 142
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
6-163 2.03e-21

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 84.75  E-value: 2.03e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   6 IRLASEQDAEKLQQLMHEAFTPLRELGIdwpsvnanLDAVKENIDKNTTFVMTIDDEIISTItvRYPWRSVKSISGYPFV 85
Cdd:COG3153    1 IRPATPEDAEAIAALLRAAFGPGREAEL--------VDRLREDPAAGLSLVAEDDGEIVGHV--ALSPVDIDGEGPALLL 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 671617087  86 WWFATNPEYEGKGYGSQLLTYVEEAfLRDtLKSAAVTLGTSARLHPWllkiYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:COG3153   71 GPLAVDPEYRGQGIGRALMRAALEA-ARE-RGARAVVLLGDPSLLPF----YERFGFRPAGELGLTLGPDEVFLAKEL 142
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 43-163 2.27e-09

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 52.66  E-value: 2.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   43 DAVKENIDK--NTTFVMTIDDEIISTITVRYPWRsvksISGypfvwwFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAA 120
Cdd:pfam13673  20 EALRERIDQgeYFFFVAFEGGQIVGVIALRDRGH----ISL------LFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSE 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 671617087  121 VTLGTSarlhPWLLKIYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:pfam13673  90 LTVNAS----PYAVPFYEKLGFRATGPEQEFNGIRFVPMEKEL 128
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 55-109 9.02e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.19  E-value: 9.02e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 671617087  55 FVMTIDDEIISTITVRYPWRSvksiSGYPFVWWFATNPEYEGKGYGSQLLTYVEE 109
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGSG----GDTAYIGDLAVLPEYRGKGIGSALLEAAEE 52
 
Name Accession Description Interval E-value
yhbS COG3153
Predicted N-acetyltransferase YhbS [General function prediction only];
6-163 2.03e-21

Predicted N-acetyltransferase YhbS [General function prediction only];


Pssm-ID: 442387 [Multi-domain]  Cd Length: 142  Bit Score: 84.75  E-value: 2.03e-21
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   6 IRLASEQDAEKLQQLMHEAFTPLRELGIdwpsvnanLDAVKENIDKNTTFVMTIDDEIISTItvRYPWRSVKSISGYPFV 85
Cdd:COG3153    1 IRPATPEDAEAIAALLRAAFGPGREAEL--------VDRLREDPAAGLSLVAEDDGEIVGHV--ALSPVDIDGEGPALLL 70

                         90       100       110       120       130       140       150
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*...
gi 671617087  86 WWFATNPEYEGKGYGSQLLTYVEEAfLRDtLKSAAVTLGTSARLHPWllkiYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:COG3153   71 GPLAVDPEYRGQGIGRALMRAALEA-ARE-RGARAVVLLGDPSLLPF----YERFGFRPAGELGLTLGPDEVFLAKEL 142
ArgA COG1246
N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and ...
 5-163 9.70e-12

N-acetylglutamate synthase or related acetyltransferase, GNAT family [Amino acid transport and metabolism]; N-acetylglutamate synthase or related acetyltransferase, GNAT family is part of the Pathway/BioSystem: Arginine biosynthesis


Pssm-ID: 440859 [Multi-domain]  Cd Length: 132  Bit Score: 59.24  E-value: 9.70e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   5 MIRLASEQDAEKLQQLMHEaftplrelgidwpsvnanlDAVKENIDknTTFVMTIDDEIISTITVRYPWrsvksiSGYPF 84
Cdd:COG1246    2 TIRPATPDDVPAILELIRP-------------------YALEEEIG--EFWVAEEDGEIVGCAALHPLD------EDLAE 54

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  85 VWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSaaVTLGTSARLHPWllkiYEKRGYEIYSEHENDDGDLG----VIMR 160
Cdd:COG1246   55 LRSLAVHPDYRGRGIGRRLLEALLAEARELGLKR--LFLLTTSAAIHF----YEKLGFEEIDKEDLPYAKVWqrdsVVME 128


                 ...
gi 671617087 161 KVL 163
Cdd:COG1246  129 KDL 131
ElaA COG2153
Predicted N-acyltransferase, GNAT family [General function prediction only];
50-163 1.04e-09

Predicted N-acyltransferase, GNAT family [General function prediction only];


Pssm-ID: 441756 [Multi-domain]  Cd Length: 134  Bit Score: 54.03  E-value: 1.04e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  50 DKNTT-FVMTIDDEIISTITVRYPWRSVKSISGypfvwwFATNPEYEGKGYGSQLLTYVEEAFLRdtLKSAAVTLgtSAR 128
Cdd:COG2153   31 DEDARhLLAYDDGELVATARLLPPGDGEAKIGR------VAVLPEYRGQGLGRALMEAAIEEARE--RGARRIVL--SAQ 100

                         90       100       110
                 ....*....|....*....|....*....|....*
gi 671617087 129 LHpwLLKIYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:COG2153  101 AH--AVGFYEKLGFVPVGEEFLEAGIPHIDMRKPL 133
RimI COG0456
Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal ...
 81-163 1.62e-09

Ribosomal protein S18 acetylase RimI and related acetyltransferases [Translation, ribosomal structure and biogenesis];


Pssm-ID: 440224 [Multi-domain]  Cd Length: 92  Bit Score: 52.35  E-value: 1.62e-09
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  81 GYPFVWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSaaVTLGTSARlHPWLLKIYEKRGYEIYSEHENDDGDLGVIMR 160
Cdd:COG0456   12 DEAEIEDLAVDPEYRGRGIGRALLEAALERARERGARR--LRLEVRED-NEAAIALYEKLGFEEVGERPNYYGDDALVME 88


                 ...
gi 671617087 161 KVL 163
Cdd:COG0456   89 KEL 91
Acetyltransf_10 pfam13673
Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase ...
 43-163 2.27e-09

Acetyltransferase (GNAT) domain; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 463953 [Multi-domain]  Cd Length: 128  Bit Score: 52.66  E-value: 2.27e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   43 DAVKENIDK--NTTFVMTIDDEIISTITVRYPWRsvksISGypfvwwFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAA 120
Cdd:pfam13673  20 EALRERIDQgeYFFFVAFEGGQIVGVIALRDRGH----ISL------LFVDPDYQGQGIGKALLEAVEDYAEKDGIKLSE 89

                          90       100       110       120
                  ....*....|....*....|....*....|....*....|...
gi 671617087  121 VTLGTSarlhPWLLKIYEKRGYEIYSEHENDDGDLGVIMRKVL 163
Cdd:pfam13673  90 LTVNAS----PYAVPFYEKLGFRATGPEQEFNGIRFVPMEKEL 128
Acetyltransf_7 pfam13508
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 50-144 4.51e-09

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 463905 [Multi-domain]  Cd Length: 84  Bit Score: 50.92  E-value: 4.51e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   50 DKNTTFVMTIDDEIISTITVRYPWRSvksisGYPFVWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAAVTLGTSARl 129
Cdd:pfam13508   1 PGGRFFVAEDDGKIVGFAALLPLDDE-----GALAELRLAVHPEYRGQGIGRALLEAAEAAAKEGGIKLLELETTNRAA- 74

                          90
                  ....*....|....*
gi 671617087  130 hpwllKIYEKRGYEI 144
Cdd:pfam13508  75 -----AFYEKLGFEE 84
MnaT COG1247
L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];
5-163 2.81e-08

L-amino acid N-acyltransferase MnaT [Amino acid transport and metabolism];


Pssm-ID: 440860 [Multi-domain]  Cd Length: 163  Bit Score: 50.76  E-value: 2.81e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   5 MIRLASEQDAEKLQQLMHEAftpLRELGIDWPSVNANLDAVKENIDKNT-----TFVMTIDDEIISTITVrYPWRSVKsi 79
Cdd:COG1247    3 TIRPATPEDAPAIAAIYNEA---IAEGTATFETEPPSEEEREAWFAAILapgrpVLVAEEDGEVVGFASL-GPFRPRP-- 76

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  80 sGYPFVWWFA--TNPEYEGKGYGSQLLTYVEEAFLRDTLKSA-AVTLGTSARlhpwLLKIYEKRGYEIYSEHENDDGDLG 156
Cdd:COG1247   77 -AYRGTAEESiyVDPDARGRGIGRALLEALIERARARGYRRLvAVVLADNEA----SIALYEKLGFEEVGTLPEVGFKFG 151

                        170
                 ....*....|..
gi 671617087 157 -----VIMRKVL 163
Cdd:COG1247  152 rwldlVLMQKRL 163
Eis COG4552
Predicted acetyltransferase [General function prediction only];
6-148 5.07e-08

Predicted acetyltransferase [General function prediction only];


Pssm-ID: 443616 [Multi-domain]  Cd Length: 393  Bit Score: 51.44  E-value: 5.07e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   6 IRLASEQDAEKLQQLMHEAFtplrelgiDWPSVNANLDAVKENIDKNTTFVMTIDDEIISTITVrYPWRSvkSISG--YP 83
Cdd:COG4552    3 IRPLTEDDLDAFARLLAYAF--------GPEPDDEELEAYRPLLEPGRVLGVFDDGELVGTLAL-YPFTL--NVGGarVP 71

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*..
gi 671617087  84 --FVWWFATNPEYEGKGYGSQLLTyveeAFLRDtLKSAAVTLGTsarLHPWLLKIYEKRGYEIYSEH 148
Cdd:COG4552   72 maGITGVAVAPEHRRRGVARALLR----EALAE-LRERGQPLSA---LYPFEPGFYRRFGYELAGDR 130
Acetyltransf_1 pfam00583
Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase ...
 29-142 1.56e-07

Acetyltransferase (GNAT) family; This family contains proteins with N-acetyltransferase functions such as Elp3-related proteins.


Pssm-ID: 395465 [Multi-domain]  Cd Length: 116  Bit Score: 47.51  E-value: 1.56e-07
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   29 RELGIDWPSVNANLDAVKENIDKNTTFVMTIDDEIISTITVRYPWRSVKsisgYPFVWWFATNPEYEGKGYGSQLLTYVE 108
Cdd:pfam00583  10 EEFPEPWPDEPLDLLEDWDEDASEGFFVAEEDGELVGFASLSIIDDEPP----VGEIEGLAVAPEYRGKGIGTALLQALL 85

                          90       100       110
                  ....*....|....*....|....*....|....
gi 671617087  109 EAFLRDTLKsaAVTLGTSARLHPwLLKIYEKRGY 142
Cdd:pfam00583  86 EWARERGCE--RIFLEVAADNLA-AIALYEKLGF 116
COG3393 COG3393
Predicted acetyltransferase, GNAT family [General function prediction only];
62-147 5.65e-07

Predicted acetyltransferase, GNAT family [General function prediction only];


Pssm-ID: 442620 [Multi-domain]  Cd Length: 86  Bit Score: 45.28  E-value: 5.65e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  62 EIISTITVRYPWRSVKSISGypfVWwfaTNPEYEGKGYGSQLLTYVEEAFLRDTLKSaaVTLGTSARlHPWLLKIYEKRG 141
Cdd:COG3393    1 ELVAMAGVRAESPGVAEISG---VY---THPEYRGRGLASALVAALAREALARGART--PFLYVDAD-NPAARRLYERLG 71


                 ....*.
gi 671617087 142 YEIYSE 147
Cdd:COG3393   72 FRPVGE 77
NAT_SF cd04301
N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer ...
 55-109 9.02e-07

N-Acyltransferase superfamily: Various enzymes that characteristically catalyze the transfer of an acyl group to a substrate; NAT (N-Acyltransferase) is a large superfamily of enzymes that mostly catalyze the transfer of an acyl group to a substrate and are implicated in a variety of functions, ranging from bacterial antibiotic resistance to circadian rhythms in mammals. Members include GCN5-related N-Acetyltransferases (GNAT) such as Aminoglycoside N-acetyltransferases, Histone N-acetyltransferase (HAT) enzymes, and Serotonin N-acetyltransferase, which catalyze the transfer of an acetyl group to a substrate. The kinetic mechanism of most GNATs involves the ordered formation of a ternary complex: the reaction begins with Acetyl Coenzyme A (AcCoA) binding, followed by binding of substrate, then direct transfer of the acetyl group from AcCoA to the substrate, followed by product and subsequent CoA release. Other family members include Arginine/ornithine N-succinyltransferase, Myristoyl-CoA: protein N-myristoyltransferase, and Acyl-homoserinelactone synthase which have a similar catalytic mechanism but differ in types of acyl groups transferred. Leucyl/phenylalanyl-tRNA-protein transferase and FemXAB nonribosomal peptidyltransferases which catalyze similar peptidyltransferase reactions are also included.


Pssm-ID: 173926 [Multi-domain]  Cd Length: 65  Bit Score: 44.19  E-value: 9.02e-07
                         10        20        30        40        50
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 671617087  55 FVMTIDDEIISTITVRYPWRSvksiSGYPFVWWFATNPEYEGKGYGSQLLTYVEE 109
Cdd:cd04301    2 LVAEDDGEIVGFASLSPDGSG----GDTAYIGDLAVLPEYRGKGIGSALLEAAEE 52
PhnO COG0454
N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, ...
 84-163 1.65e-05

N-acetyltransferase, GNAT superfamily (includes histone acetyltransferase HPA2) [Transcription, General function prediction only];


Pssm-ID: 440222 [Multi-domain]  Cd Length: 136  Bit Score: 42.35  E-value: 1.65e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087  84 FVWWFATNPEYEGKGYGSQLLTYVEEAFLRDTLKSAAVTLGtsaRLHPWLLKIYEKRGYEIYSEHENddgDLGVIMRKVL 163
Cdd:COG0454   60 ELKRLYVLPEYRGKGIGKALLEALLEWARERGCTALELDTL---DGNPAAIRFYERLGFKEIERYVA---YVGGEFEKEL 133
RimL COG1670
Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, ...
 6-143 4.29e-04

Protein N-acetyltransferase, RimJ/RimL family [Translation, ribosomal structure and biogenesis, Posttranslational modification, protein turnover, chaperones];


Pssm-ID: 441276 [Multi-domain]  Cd Length: 173  Bit Score: 39.21  E-value: 4.29e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087   6 IRLASEQDAEKLQQLMH--EAFTPLRELGIDWPSVNANLDAVKENIDKNTTFVMTI----DDEIISTITVRYPWRSVKSI 79
Cdd:COG1670   10 LRPLRPEDAEALAELLNdpEVARYLPGPPYSLEEARAWLERLLADWADGGALPFAIedkeDGELIGVVGLYDIDRANRSA 89

                         90       100       110       120       130       140
                 ....*....|....*....|....*....|....*....|....*....|....*....|....
gi 671617087  80 SgypFVWWFAtnPEYEGKGYGSQLLTYVEEaFLRDTLKSAAVTLGTSARLHPWlLKIYEKRGYE 143
Cdd:COG1670   90 E---IGYWLA--PAYWGKGYATEALRALLD-YAFEELGLHRVEAEVDPDNTAS-IRVLEKLGFR 146
Acetyltransf_9 pfam13527
Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.
 6-144 6.08e-04

Acetyltransferase (GNAT) domain; This domain catalyzes N-acetyltransferase reactions.


Pssm-ID: 404421 [Multi-domain]  Cd Length: 124  Bit Score: 37.94  E-value: 6.08e-04
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671617087    6 IRLASEQDAEKLQQLMHEAFTPLRELGIDwpsvnanlDAVKENIDKNTTFVMTIDDEIISTITVrYPWRSvkSISGYPF- 84
Cdd:pfam13527   1 IRPLTEDEFDEVLRLLEYAFQDEDSPELR--------EYFRPLLEEGRVLGAFDDGELVSTLAL-YPFEL--NVPGKTLp 69

                          90       100       110       120       130       140
                  ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 671617087   85 ---VWWFATNPEYEGKGYGSQLLTYVEEaflrdTLKSAAVTLGTsarLHPWLLKIYEKRGYEI 144
Cdd:pfam13527  70 aagITGVATYPEYRGRGVMSRLLRRSLE-----EMRERGVPLSF---LYPSSYPIYRRFGYEI 124
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH