NCBI Home Page NCBI Site Search page NCBI Guide that lists and describes the NCBI resources
Conserved domains on  [gi|671343612|gb|AII77128|]
View 

ABC transporter, permease protein [Bifidobacterium adolescentis]

Protein Classification

carbohydrate ABC transporter permease( domain architecture ID 10003067)

carbohydrate ABC transporter permease is the transmembrane (TM) subunit of a periplasmic binding protein (PBP)-dependent ATP-binding cassette (ABC) transporter responsible for the translocation across the membrane of one or more from a variety of carbohydrate substrates including trehalose, lactose, arabinose, and maltodextrin

Gene Ontology:  GO:0042626|GO:0140359|GO:0008643|GO:0055085
PubMed:  25750732|24638992|30626703
TCDB:  3.A.1.1.-

Graphical summary

 Zoom to residue level

show extra options »

Show site features     Horizontal zoom: ×

List of domain hits

 Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
7-305 1.90e-87

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


:

Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 263.53  E-value: 1.90e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   7 KTKTEGSGNVLRRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITskdlRTPFNVNFVGLDQYIALFHDRRFLHA 86
Cdd:COG1175    2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWN----LLGPPPEFVGLDNYARLFTDPRFWNA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  87 LGVTGIFVLVGLPITMVIALAFAVALNKGSKhLNAFFRAVFYAPVVASVVAVSVVWRYILQKD-GLLNSLLAVFGIAGPD 165
Cdd:COG1175   78 LGNTLLFTVVSVPLQLVLGLLLALLLNRKLR-GRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGLEPIN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 166 WLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQF 245
Cdd:COG1175  157 WLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQV 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 671343612 246 FEESFVMTQGGPLDSTLSAAYYVYQK-FGFGQYGIASAASWVLFIIIALVSVLQFRILKED 305
Cdd:COG1175  237 FDLVYVLTGGGPGNSTTTLVLYIYQTaFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
7-305 1.90e-87

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 263.53  E-value: 1.90e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   7 KTKTEGSGNVLRRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITskdlRTPFNVNFVGLDQYIALFHDRRFLHA 86
Cdd:COG1175    2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWN----LLGPPPEFVGLDNYARLFTDPRFWNA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  87 LGVTGIFVLVGLPITMVIALAFAVALNKGSKhLNAFFRAVFYAPVVASVVAVSVVWRYILQKD-GLLNSLLAVFGIAGPD 165
Cdd:COG1175   78 LGNTLLFTVVSVPLQLVLGLLLALLLNRKLR-GRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGLEPIN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 166 WLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQF 245
Cdd:COG1175  157 WLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQV 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 671343612 246 FEESFVMTQGGPLDSTLSAAYYVYQK-FGFGQYGIASAASWVLFIIIALVSVLQFRILKED 305
Cdd:COG1175  237 FDLVYVLTGGGPGNSTTTLVLYIYQTaFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
63-300 1.39e-16

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 77.94  E-value: 1.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  63 PFNVN--FVGLDQYIALFHDRRFLHALGVTGIFVLVGLPITMVIALAFAvALNKGSKHLNAFFRAVFYAPVVASVVAVSV 140
Cdd:PRK10561  31 PFGFSsqFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFA-ALVDYVVRGSRFYQTLMLLPYAVAPAVAAV 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 141 VWRYILQKD-GLLNSLLAVFGIagpDWLH--DTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWR 217
Cdd:PRK10561 110 LWIFLFNPGrGLITHFLAEFGY---DWNHaqNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIR 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 218 IFRSITLPLLKPTLLLGAVL-LSVAYLQFFEESFVMTQGGPLDSTLSAAYYVYQKfGFGQYGIASAA--SWVLFIIIALV 294
Cdd:PRK10561 187 RFFKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYRE-GFTGLDLSSSAaqSVVLMFLVIVL 265


                 ....*.
gi 671343612 295 SVLQFR 300
Cdd:PRK10561 266 TVVQFR 271
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 23-222 6.23e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 56.61  E-value: 6.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   23 ILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITSkdlrtpfnvNFVGLDQYIALFHDRRFLHALGVTGIFVLVGLPITM 102
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDG---------DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  103 VIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLLAVFGIAGPdwlhdtryaLPALMVMTI 182
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIYGF---------WGIVIGEVF 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 671343612  183 WRNMGTLMIIfLAGLQAIPEELKEAAAIDGAGKWRIFRSI 222
Cdd:TIGR03262 143 YTFPHALMIL-VTALSLADGRLYEAARAMGASPWRTFFTV 181
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-293 2.19e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.19  E-value: 2.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  87 LGVTGIFVLVGLPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGllnsllavfgiagpDW 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLL--------------GW 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 167 LHDTRYALPALMVMTIWRnMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQff 246
Cdd:cd06261   67 GILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG-- 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 671343612 247 EESFVMTQGGPLDSTLSAAYYVYQKFGFGQYGIASAASWVLFIIIAL 293
Cdd:cd06261  144 EFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 152-303 1.99e-03

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 38.43  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  152 LNSLLAVFGIAGPDWLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTL 231
Cdd:pfam00528  30 LPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPI 109

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671343612  232 LLGAVLLSVAYLQFFEESFVMTQGGPLDSTLSAAYYVYqkfgfgQYGIASAASWVLFIIIALVSVLQFRILK 303
Cdd:pfam00528 110 LTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGY------DYPEIQGPVLAAALILLLLNLLVDILQR 175
 
Name Accession Description Interval E-value
UgpA COG1175
ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];
7-305 1.90e-87

ABC-type sugar transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440788 [Multi-domain]  Cd Length: 298  Bit Score: 263.53  E-value: 1.90e-87
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   7 KTKTEGSGNVLRRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITskdlRTPFNVNFVGLDQYIALFHDRRFLHA 86
Cdd:COG1175    2 TTTTSAAARRRRRRRRLAAYLFLLPALLLLLVFVLYPLLYTLYLSFTDWN----LLGPPPEFVGLDNYARLFTDPRFWNA 77

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  87 LGVTGIFVLVGLPITMVIALAFAVALNKGSKhLNAFFRAVFYAPVVASVVAVSVVWRYILQKD-GLLNSLLAVFGIAGPD 165
Cdd:COG1175   78 LGNTLLFTVVSVPLQLVLGLLLALLLNRKLR-GRGFFRTLFFLPWVISPVVVALIWKWLFNPDyGLLNALLGALGLEPIN 156

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 166 WLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQF 245
Cdd:COG1175  157 WLGDPSLALPAVIIVTVWKGTGFNMLIFLAGLQSIPRELYEAARIDGASPWQRFRRITLPLLRPTILFVLVLSTIGALQV 236

                        250       260       270       280       290       300
                 ....*....|....*....|....*....|....*....|....*....|....*....|.
gi 671343612 246 FEESFVMTQGGPLDSTLSAAYYVYQK-FGFGQYGIASAASWVLFIIIALVSVLQFRILKED 305
Cdd:COG1175  237 FDLVYVLTGGGPGNSTTTLVLYIYQTaFQQFDFGYASAIAVVLFLIILVLTLLQLRLLRRR 297
LplB COG4209
ABC-type polysaccharide transport system, permease component [Carbohydrate transport and ...
 5-222 4.10e-23

ABC-type polysaccharide transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 443357 [Multi-domain]  Cd Length: 316  Bit Score: 96.70  E-value: 4.10e-23
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   5 TRKTKTEGSGNVLRRRRTILAwgFALPFAVVFCVFMLIPLLSsMAMSFTDItsKDLRTPFNVNFVGLDQYIALFHDRRFL 84
Cdd:COG4209   11 KKKKRKKSFLKRLKRDWQLYL--MLLPGLIYLLIFSYLPMYG-IVIAFKDY--NPFKGIFGSPWVGLKNFKFLFSSPDFW 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  85 HALGVTGIFVLVGLPITMVIALAFAVALNK-GSKHLNAFFRAVFYAPVVASVVAVSVVWRYIL-QKDGLLNSLLAVFGIA 162
Cdd:COG4209   86 RVLRNTLLISLLKLVFGFPLPIILALLLNElRSKRFKKTVQTISYLPHFLSWVVVAGIVYQFLsPDTGLVNQLLRALGGE 165

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 163 GPDWLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSI 222
Cdd:COG4209  166 PINFLTEPKYFRPIYVFSGIWKEAGWGSIIYLAAITGIDPELYEAAAIDGAGRWQQIWHI 225
PotB COG1176
ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport ...
 18-305 1.95e-17

ABC-type spermidine/putrescine transport system, permease component I [Amino acid transport and metabolism];


Pssm-ID: 440789 [Multi-domain]  Cd Length: 287  Bit Score: 80.58  E-value: 1.95e-17
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  18 RRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITSKDLRTPFnvnfVGLDQYIALFHDRRFLHALGVTGIFVLVG 97
Cdd:COG1176    4 ALRRRLRPLLLLLPALLWLLLFFVLPLLLLLVYSFTTRDPYGGVVPG----FTLENYARLFTDPLYLKVLLRTLWIALLT 79

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  98 LPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLLAVFGIAGP--DWLHDTR---- 171
Cdd:COG1176   80 TLICLLLGYPIAYFLARAPPRWRNLLLLLVILPFWTSFLVRTYAWIVLLGRNGLLNSLLLALGLIDEplRLLYTEFavvi 159

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 172 ---YALPALMVMTIWrnmgtlmiiflAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQFFEE 248
Cdd:COG1176  160 glvYVYLPFMVLPLY-----------AALEKIDPSLLEAARDLGASPWQTFRRVILPLSLPGIIAGSLLVFIPALGAFVT 228

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....*...
gi 671343612 249 SFVMtqGGPldSTLSAAYYVYQKFG-FGQYGIASAASWVLFIIIALVSVLQFRILKED 305
Cdd:COG1176  229 PALL--GGG--KVLMIGNLIYQQFLsALNWPLAAALAVVLLLIVLLVLLLYLRLLRRR 282
PRK10561 PRK10561
sn-glycerol-3-phosphate ABC transporter permease UgpA;
63-300 1.39e-16

sn-glycerol-3-phosphate ABC transporter permease UgpA;


Pssm-ID: 182550 [Multi-domain]  Cd Length: 280  Bit Score: 77.94  E-value: 1.39e-16
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  63 PFNVN--FVGLDQYIALFHDRRFLHALGVTGIFVLVGLPITMVIALAFAvALNKGSKHLNAFFRAVFYAPVVASVVAVSV 140
Cdd:PRK10561  31 PFGFSsqFVGLDNFVALFHDSYYLDSFWTTIKFSTLVTVSGLLVSLFFA-ALVDYVVRGSRFYQTLMLLPYAVAPAVAAV 109

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 141 VWRYILQKD-GLLNSLLAVFGIagpDWLH--DTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWR 217
Cdd:PRK10561 110 LWIFLFNPGrGLITHFLAEFGY---DWNHaqNSGQAMFLVVFASVWKQISYNFLFFFAALQSIPRSLVEAAAIDGAGPIR 186

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 218 IFRSITLPLLKPTLLLGAVL-LSVAYLQFFEESFVMTQGGPLDSTLSAAYYVYQKfGFGQYGIASAA--SWVLFIIIALV 294
Cdd:PRK10561 187 RFFKLALPLIAPVSFFLLVVnLVYAFFDTFPVIDAATSGGPVQATTTLIYKIYRE-GFTGLDLSSSAaqSVVLMFLVIVL 265


                 ....*.
gi 671343612 295 SVLQFR 300
Cdd:PRK10561 266 TVVQFR 271
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
15-303 2.17e-12

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 67.11  E-value: 2.17e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  15 NVLRRRRTILAWGFAlpfAVVFCVFMLIPLLSSMAMSFTDitskdlrtpfnvnfvGLDQYIALFHDRRFLHALGVTGIFV 94
Cdd:COG1178    2 STRPRRRPRLLLLLL---ALLLALLVLLPLLALLLRAFTD---------------GLANFWALLSDPYLWRALGNTLLLA 63

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  95 LVGLPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLL-AVFGIAGPDWlhdtrYA 173
Cdd:COG1178   64 LLVTLLSLLLGVPLAWLLARTDFPGRRLLRWLLLLPLALPPYVVALAWIALFGPNGLLNTLLrALFGLEPPDI-----YG 138

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 174 LPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLsvaylqFFE--ESF- 250
Cdd:COG1178  139 LGGIILVLVLFNYPYVYLLLRAALRSIDASLEEAARSLGASPWRAFRRVTLPLLRPAIAAGALLV------FLLclADFg 212

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|....
gi 671343612 251 -VMTQGGPLDsTLSAAYYVyQKFGFGQYGIASAASWVLFIIIALVSVLQFRILK 303
Cdd:COG1178  213 tPLVLGGGYT-TLTTAIYQ-AWLGDFDLGAAAALALVLLLLVLLLLLLERRLRR 264
UgpE COG0395
ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and ...
 18-222 7.95e-12

ABC-type glycerol-3-phosphate transport system, permease component [Carbohydrate transport and metabolism];


Pssm-ID: 440164 [Multi-domain]  Cd Length: 282  Bit Score: 64.35  E-value: 7.95e-12
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  18 RRRRTILAWGFALpFAVVFCVFMLIPLLSSMAMSF---TDITSKDLRTPFNVnfVGLDQYIALFHDRRFLHALGVTGIFV 94
Cdd:COG0395    7 RRRRRLGRILLYL-LLILLALLFLFPLYWMVVTSFkppAEIFSGPPSLLPSE--FTLENYRAAFTDGPFGRYLLNSLIVA 83

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  95 LVGLPITMVIALAFAVAL----NKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYIlqkdGLLNSLLAVfgiagpdwlhdt 170
Cdd:COG0395   84 VVSTVLSLLLSSLAAYALarfrFRGRKLLFLLILATLMIPGQVLLIPLYLLFRQL----GLLNTYWGL------------ 147

                        170       180       190       200       210
                 ....*....|....*....|....*....|....*....|....*....|....*
gi 671343612 171 ryALPAL---MVMTIWrnmgtLMIIFLAGlqaIPEELKEAAAIDGAGKWRIFRSI 222
Cdd:COG0395  148 --ILPYLafgLPFGIF-----LLRQFFRS---IPRELEEAARIDGASEFRIFWRI 192
PotC COG1177
ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport ...
 32-303 4.90e-11

ABC-type spermidine/putrescine transport system, permease component II [Amino acid transport and metabolism];


Pssm-ID: 440790 [Multi-domain]  Cd Length: 262  Bit Score: 61.67  E-value: 4.90e-11
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  32 FAVVFCVFMLIPLLSSMAMSFTDitSKDLRTPFNVnfVGLDQYIALFHDRRFLHALGVTGIFVLVGLPITMVIALAFAVA 111
Cdd:COG1177   12 FLALVLLFLYLPILVLVLYSFND--SWFLTFPPEG--FTLRWYAELFSDPRLLDALLNSLLIALLSTLLATVLGTPAALA 87

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 112 LNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLLAVFGIagpdwlhdtrYALPALMVMtiwrnmgtlMI 191
Cdd:COG1177   88 LARYRFRGRRLLLALLLLPLVVPGIVLGVALLLLFSALGLSGGLWGLILA----------HVVFTLPFV---------VL 148

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 192 IFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLlsvAYLQFFEEsFVMTQ--GGPLDSTLSaaYYVY 269
Cdd:COG1177  149 VVLARLQGFDPSLEEAARDLGASPWQTFRRVTLPLIAPGILAGALL---AFTLSFDE-FVITLflAGPGVTTLP--VYIY 222

                        250       260       270
                 ....*....|....*....|....*....|....
gi 671343612 270 QKFGFGQYGIASAASWVLFIIIALVSVLQFRILK 303
Cdd:COG1177  223 SMIRRGISPEINALSTLLILLSLLLLLLAERLRR 256
PhnU2 TIGR03262
putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding ...
 23-222 6.23e-09

putative 2-aminoethylphosphonate ABC transporter, permease protein; [Transport and binding proteins, Amino acids, peptides and amines]


Pssm-ID: 274495 [Multi-domain]  Cd Length: 546  Bit Score: 56.61  E-value: 6.23e-09
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612   23 ILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITSkdlrtpfnvNFVGLDQYIALFHDRRFLHALGVTGIFVLVGLPITM 102
Cdd:TIGR03262   1 LIARLLLAGMILALLLFLLLPLLALLTKSVYDSDG---------DFIGLANFAEYFATPGLLQSLGNSLTVSAIVTAIVV 71

                          90       100       110       120       130       140       150       160
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  103 VIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLLAVFGIAGPdwlhdtryaLPALMVMTI 182
Cdd:TIGR03262  72 PLAFAFAYALTRSRIPGKGAFRLVALLPLLAPSLLPAISLIYLFGNQGLLKGLLGGFSIYGF---------WGIVIGEVF 142

                         170       180       190       200
                  ....*....|....*....|....*....|....*....|
gi 671343612  183 WRNMGTLMIIfLAGLQAIPEELKEAAAIDGAGKWRIFRSI 222
Cdd:TIGR03262 143 YTFPHALMIL-VTALSLADGRLYEAARAMGASPWRTFFTV 181
malF PRK10999
maltose ABC transporter permease MalF;
147-303 3.91e-08

maltose ABC transporter permease MalF;


Pssm-ID: 236816 [Multi-domain]  Cd Length: 520  Bit Score: 54.20  E-value: 3.91e-08
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 147 QKDGLLNSLL-AVFGIAgPDWLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLP 225
Cdd:PRK10999 348 QSFGEINMMLsALFGIK-PAWFSDPTLAKTMILIVNTWLGYPYMMILCMGLLKAIPDDLYEASAMDGAGPFQNFFKITLP 426

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 226 LLKPTLLLgavlLSVAYLQFFEESFVM----TQGGP--LDSTLSAAY------YVYQ-KF--GFGQ-YGIASAASWVLFI 289
Cdd:PRK10999 427 LLIKPLTP----LMIASFAFNFNNFVLiqllTNGGPdmIGTTTPAGYtdllvsYTYRiAFegGGGQdFGLAAAIATLIFL 502

                        170
                 ....*....|....
gi 671343612 290 IIALVSVLQFRILK 303
Cdd:PRK10999 503 LVGALAILNLKATK 516
FbpB COG1178
ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];
18-303 7.78e-07

ABC-type Fe3+ transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440791 [Multi-domain]  Cd Length: 538  Bit Score: 50.16  E-value: 7.78e-07
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  18 RRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITSKDLrtpfnvnfvGLDQYIALFHDRRFLHALGVTGIFVLVG 97
Cdd:COG1178  280 RVKLGRWRWLALALCLLLVLLGLLLPLLALLLWSLTKALDDNL---------TLDNYRFVLLDPSLLRALLNSLLLALLA 350

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  98 LPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVsvvwryilqkdGLlnSLLAVFGIAGPDWLHDTRYALPAL 177
Cdd:COG1178  351 ALLAVLLALLLAYLVRRRRGRLARLLDRLAMLPYAVPGIVL-----------GL--GLLLLFNRPLPLLLYGTLAILVLA 417

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 178 MVMtiwRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLlsvAYLQFFEE----SFVMT 253
Cdd:COG1178  418 YVV---RFLPFALRSLEAALAQIDPSLEEAARSLGASPLRTLRRVTLPLLRPGLLAAALL---VFVTSMKElsatLLLRP 491

                        250       260       270       280       290
                 ....*....|....*....|....*....|....*....|....*....|
gi 671343612 254 QGgpldsTLSAAYYVYQKFGFGQYGIASAASWVLFIIIALVSVLQFRILK 303
Cdd:COG1178  492 PG-----FETLAVLIYQLASSGRYGEAAALALLLVLVSLLPVLLLERLLG 536
MalG COG3833
ABC-type maltose transport system, permease component MalG [Carbohydrate transport and ...
 18-222 1.21e-05

ABC-type maltose transport system, permease component MalG [Carbohydrate transport and metabolism];


Pssm-ID: 443045 [Multi-domain]  Cd Length: 282  Bit Score: 45.91  E-value: 1.21e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  18 RRRRTILAWGFALPFAVVFCVFMLIPLLSSMAMSFTDITSKDLRTPFNVNFvGLDQYIALFHDRRFLHALGVTGIFVLVG 97
Cdd:COG3833    7 RKRRRRLKLGLRHLVLIILAIIALFPILWVVSASFNPGGSLYSSSLIPENF-TLENYKKLFTETPFLRWFLNSLIVAVVT 85

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  98 LPITMVIALAFAVALN----KGSKH-LNAF-----------FRAVFYapvvasvvavsvvwryILQKDGLLNSLLA--VF 159
Cdd:COG3833   86 AIISVFLAALAAYAFSrfrfKGRKAgLLALlllqmfpaflaLVALYL----------------LLSALGLLNTLLGliLV 149

                        170       180       190       200       210       220
                 ....*....|....*....|....*....|....*....|....*....|....*....|...
gi 671343612 160 GIAGpdwlhdtryALPalmvMTIWrnmgtLMIIFLaglQAIPEELKEAAAIDGAGKWRIFRSI 222
Cdd:COG3833  150 YLGG---------AIP----FNTW-----LMKGYF---DTIPKELDEAAKIDGASHFQIFFRI 191
TM_PBP2 cd06261
Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding ...
 87-293 2.19e-05

Transmembrane subunit (TM) found in Periplasmic Binding Protein (PBP)-dependent ATP-Binding Cassette (ABC) transporters which generally bind type 2 PBPs. These types of transporters consist of a PBP, two TMs, and two cytoplasmic ABC ATPase subunits, and are mainly involved in importing solutes from the environment. The solute is captured by the PBP which delivers it to a gated translocation pathway formed by the two TMs. The two ABCs bind and hydrolyze ATP and drive the transport reaction. For these transporters the ABCs and TMs are on independent polypeptide chains. These systems transport a diverse range of substrates. Most are specific for a single substrate or a group of related substrates; however some transporters are more promiscuous, transporting structurally diverse substrates such as the histidine/lysine and arginine transporter in Enterobacteriaceae. In the latter case, this is achieved through binding different PBPs with different specificities to the TMs. For other promiscuous transporters such as the multiple-sugar transporter Msm of Streptococcus mutans, the PBP has a wide substrate specificity. These transporters include the maltose-maltodextrin, phosphate and sulfate transporters, among others.


Pssm-ID: 119394 [Multi-domain]  Cd Length: 190  Bit Score: 44.19  E-value: 2.19e-05
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  87 LGVTGIFVLVGLPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGllnsllavfgiagpDW 166
Cdd:cd06261    1 LLNTLLLALIATLLALVLGLLLGIILARKRGKLDRLLRRIIDLLLSLPSLVLGLLLVLLFGVLL--------------GW 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 167 LHDTRYALPALMVMTIWRnMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLLSVAYLQff 246
Cdd:cd06261   67 GILPGLGLPALILALLLI-APFARLIRRAALESIPKDLVEAARALGASPWQIFRRIILPLALPPILTGLVLAFARALG-- 143

                        170       180       190       200
                 ....*....|....*....|....*....|....*....|....*..
gi 671343612 247 EESFVMTQGGPLDSTLSAAYYVYQKFGFGQYGIASAASWVLFIIIAL 293
Cdd:cd06261  144 EFALVSFLGGGEAPGPGTGLLLIFAILFPGDLGVAAAVALILLLLSL 190
CysU COG0555
ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism]; ...
 18-302 5.43e-04

ABC-type sulfate transport system, permease component [Inorganic ion transport and metabolism];


Pssm-ID: 440321 [Multi-domain]  Cd Length: 268  Bit Score: 40.89  E-value: 5.43e-04
                         10        20        30        40        50        60        70        80
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  18 RRRRTILAWGFALPfAVVFCVFMLIPLLSSMAMSFTditskdlrtpfnvnfVGLDQYIALFHDRRFLHALGVTGIFVLVG 97
Cdd:COG0555    3 RRVLPGFGLTLGLT-LLYLSLIVLLPLAALVLKAAG---------------LGWAEFWAVLTSPRVLAALKLSLGTALIA 66

                         90       100       110       120       130       140       150       160
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  98 LPITMVIALAFAVALNKGSKHLNAFFRAVFYAPVVASVVAVSVVWRYILQKDGLLNSLLAVFGIAGPdwlhdtrYALPAL 177
Cdd:COG0555   67 ALINLVFGLPLAWVLVRYRFPGKRLVDALVDLPFALPTAVAGIALLLLFGPNGWLGQLLAPLGIKVA-------FTPLGI 139

                        170       180       190       200       210       220       230       240
                 ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612 178 MVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTLLLGAVLlsvAYLQFFEE--SFVMTQG 255
Cdd:COG0555  140 VLAQTFVSLPFVVRTVQPVLEELDPELEEAAATLGASRWQTFRRVILPLLLPALLTGFAL---AFARALGEfgAVIFIAG 216

                        250       260       270       280
                 ....*....|....*....|....*....|....*....|....*..
gi 671343612 256 GPLDSTLSAAYYVYQKFGFGQYGIASAASWVLfIIIALVSVLQFRIL 302
Cdd:COG0555  217 NLPMKTEILPLLIYLKLEEGDYAGATAIALVL-LLISFLLLLLINLL 262
BPD_transp_1 pfam00528
Binding-protein-dependent transport system inner membrane component; The alignments cover the ...
 152-303 1.99e-03

Binding-protein-dependent transport system inner membrane component; The alignments cover the most conserved region of the proteins, which is thought to be located in a cytoplasmic loop between two transmembrane domains. The members of this family have a variable number of transmembrane helices.


Pssm-ID: 334128 [Multi-domain]  Cd Length: 183  Bit Score: 38.43  E-value: 1.99e-03
                          10        20        30        40        50        60        70        80
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|....*....|
gi 671343612  152 LNSLLAVFGIAGPDWLHDTRYALPALMVMTIWRNMGTLMIIFLAGLQAIPEELKEAAAIDGAGKWRIFRSITLPLLKPTL 231
Cdd:pfam00528  30 LPSFVLAILLVVIAILSILGHGILPAIILALLGWAGYARLIRRAALRSLPSDLVEAARALGASRWQIFRKIILPNALPPI 109

                          90       100       110       120       130       140       150
                  ....*....|....*....|....*....|....*....|....*....|....*....|....*....|..
gi 671343612  232 LLGAVLLSVAYLQFFEESFVMTQGGPLDSTLSAAYYVYqkfgfgQYGIASAASWVLFIIIALVSVLQFRILK 303
Cdd:pfam00528 110 LTGLALAFGGALGGAVLLEFLGSWPGLGLLLIEAILGY------DYPEIQGPVLAAALILLLLNLLVDILQR 175
 
Blast search parameters
Data Source: Precalculated data, version = cdd.v.3.21
Preset Options:Database: CDSEARCH/cdd   Low complexity filter: no  Composition Based Adjustment: yes   E-value threshold: 0.01

References:

  • Wang J et al. (2023), "The conserved domain database in 2023", Nucleic Acids Res.51(D)384-8.
  • Lu S et al. (2020), "The conserved domain database in 2020", Nucleic Acids Res.48(D)265-8.
  • Marchler-Bauer A et al. (2017), "CDD/SPARCLE: functional classification of proteins via subfamily domain architectures.", Nucleic Acids Res.45(D)200-3.
Help | Disclaimer | Write to the Help Desk
NCBI | NLM | NIH